Hub : Genes

Gfral

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Gfral 0.7 0.1 1.7e-15 0.56 0.46 0.54 0.56 4.9e-16 2.1e-12 2.7e-15 4.0e-16
2 IC gene expression Gfral 0.67 0.09 0.0e+00 0.55 0.51 0.52 0.54 6.3e-27 1.8e-24 6.0e-25 3.6e-26
3 PL gene expression Gfral 0.65 0.11 0.0e+00 0.5 0.47 0.49 0.49 4.6e-62 8.2e-57 2.7e-60 2.0e-60
4 Brain intron excision ratio chr8_85837081_85839699 0.07 0.04 2.7e-04 0.02 0.03 0.03 0.04 9.5e-03 8.9e-04 2.1e-03 8.4e-05
5 PL alternative TSS XM_039081963.2 0.07 0.03 6.2e-06 0.06 0.05 0.05 0.05 3.2e-07 6.0e-06 4.2e-06 3.4e-06
6 Brain intron excision ratio chr8_85837426_85839699 0.06 0.04 1.9e-03 0.03 0.01 0.01 0.01 1.7e-03 5.2e-02 5.1e-02 1.7e-02
7 BLA alternative TSS XM_039081963.2 0.23 0.1 1.4e-05 0.07 0.07 0.04 0.06 8.0e-05 1.5e-04 2.3e-03 6.3e-04
8 IL gene expression Gfral 0.64 0.11 1.5e-10 0.34 0.24 0.3 0.3 7.0e-09 1.8e-06 8.1e-08 4.5e-08
9 Brain intron excision ratio chr8_85839833_85843480 0.04 0.02 6.9e-03 0.01 0.02 0.01 0.02 1.3e-02 3.9e-03 1.7e-02 1.0e-02
10 Brain gene expression Gfral 0.22 0.11 1.9e-09 0.09 0.11 0.1 0.09 1.7e-08 1.7e-10 7.1e-10 8.6e-09
11 BLA gene expression Gfral 0.52 0.1 0.0e+00 0.36 0.35 0.36 0.37 9.7e-20 2.0e-19 2.7e-20 1.3e-20
12 IC alternative TSS XM_039081963.2 0.14 0.07 4.3e-03 0.06 0.07 0.07 0.06 2.3e-03 5.0e-04 6.0e-04 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.40.81.80.6-0.9-0.9-1.10.8-0.90.9-0.9-0.30.51.0-1.3
Area under the delay curve0.50.71.4-1.20.80.80.7-0.90.9-1.01.00.90.6-0.8-0.1
BMI with tail3.612.523.4-4.23.93.93.4-4.03.9-3.53.54.8-0.7-3.1-1.1
BMI without tail0.63.18.2-2.12.02.01.1-2.01.7-1.61.62.90.4-1.3-1.2
Body weight3.816.630.7-4.64.84.73.8-4.64.4-4.04.05.5-1.1-3.7-0.5
Weight adjusted by age0.20.51.4-1.20.20.30.4-0.30.4-1.01.00.40.8-0.7-0.6
Bone surface0.61.15.2-0.2-0.7-0.7-0.90.7-0.70.7-0.70.11.81.1-2.3
Bone volume0.20.42.4-0.2-0.3-0.3-0.50.3-0.30.4-0.40.31.10.6-1.5
Breakpoint value in progressive ratio session0.10.32.0-0.30.20.2-0.5-0.4-0.20.1-0.10.11.40.4-0.6
Number of licking bursts0.10.31.6-0.80.20.20.1-0.30.2-0.30.30.61.30.0-1.1
Context. condit. distance diff. score0.10.10.5-0.50.20.20.5-0.20.3-0.30.3-0.30.4-0.20.7
Locomotion velocity, session 10.20.20.3-0.30.50.50.1-0.40.4-0.50.50.50.4-0.40.2
Locomotion distance, session 12.02.53.21.7-1.6-1.6-1.81.6-1.81.7-1.7-1.11.41.6-1.1
Locomotion velocity, session 20.20.22.0-0.0-0.2-0.1-0.50.2-0.20.0-0.0-0.11.40.2-0.3
Locomotion distance, session 20.91.22.91.0-0.9-0.9-1.50.9-1.11.0-1.0-0.21.71.0-1.2
Locomotion velocity, session 35.86.67.82.2-2.7-2.7-2.72.7-2.82.7-2.7-2.22.22.8-2.4
Locomotion distance, session 36.47.38.83.0-2.9-2.9-2.92.9-2.93.0-3.0-2.51.52.9-1.6
Stereotopy head waving bouts, day 30.10.20.80.2-0.3-0.30.30.3-0.30.2-0.2-0.9-0.70.10.4
Stereotopy head waving duration, day 30.60.81.9-0.70.70.71.3-0.70.7-0.70.7-0.0-1.4-0.81.1
Locomotion velocity, session 70.80.81.40.8-1.1-1.1-0.91.2-1.00.8-0.8-0.90.50.7-0.8
Locomotion distance, session 70.60.82.10.6-0.9-0.9-0.91.0-0.80.7-0.7-0.91.50.8-0.3
Stereotopy head waving bouts, day 72.32.73.71.5-1.7-1.7-1.51.7-1.71.8-1.8-1.61.11.9-1.3
Stereotopy head waving duration, day 72.12.63.71.4-1.6-1.6-1.61.7-1.61.8-1.8-1.31.11.9-1.8
Locomotion velocity, session 81.82.13.41.2-1.4-1.4-1.51.4-1.51.5-1.5-0.91.81.6-1.7
Locomotion distance, session 81.42.05.11.0-1.4-1.4-1.51.4-1.41.3-1.3-1.12.31.4-1.1
Degree of sensitization distance3.23.44.6-2.11.91.92.0-1.92.0-2.12.11.3-0.2-2.01.8
Degree of sensitization stereotypy2.42.73.91.5-1.6-1.7-1.71.7-1.61.8-1.8-1.41.32.0-1.5
Conditioned locomotion0.60.71.5-0.30.70.80.8-0.80.8-0.90.90.8-1.2-1.10.5
Cocaine response after cond. corrected0.91.32.0-1.41.31.41.2-1.41.3-1.21.21.00.2-1.00.6
Cocaine response after cond. not corrected2.73.95.3-2.22.32.32.2-2.32.2-2.02.01.7-0.6-1.91.3
Cocaine response before conditioning2.22.63.8-1.81.81.81.7-1.81.8-1.71.71.9-0.7-1.60.4
Saline control response0.40.61.60.7-0.8-0.7-0.10.7-0.80.9-0.9-1.3-0.40.70.3
Bone: connectivity density3.15.07.12.1-2.3-2.3-2.72.4-2.42.4-2.4-1.41.02.5-2.5
Bone: cortical apparent density0.40.63.50.9-0.2-0.10.10.1-0.20.3-0.3-0.7-1.6-0.11.9
Bone: cortical area0.40.72.8-0.70.60.61.2-0.60.7-0.50.5-0.2-0.9-0.61.7
Bone: cortical porosity0.10.10.7-0.0-0.1-0.10.20.2-0.00.1-0.1-0.0-0.8-0.1-0.3
Bone: cortical porosity0.20.20.30.3-0.5-0.5-0.30.6-0.40.4-0.4-0.4-0.50.3-0.4
Bone: cortical thickness0.71.26.30.40.20.30.9-0.30.3-0.20.2-0.7-2.3-0.72.5
Bone: cortical thickness1.82.24.6-1.01.41.31.6-1.41.3-1.41.40.7-2.1-1.62.0
Bone: cortical tissue density0.40.63.10.9-0.2-0.20.10.1-0.20.3-0.3-0.7-1.5-0.11.8
Condit. Reinf. active minus inactive responses0.40.42.00.0-0.2-0.2-0.90.2-0.20.1-0.10.71.40.3-1.4
Condit. Reinf. active-inactive response ratio0.91.01.3-1.11.11.11.1-1.11.0-1.11.10.9-0.5-1.10.6
Condit. Reinf. active responses1.41.86.00.7-1.0-1.0-1.81.0-1.00.9-0.90.12.41.2-2.3
Condit. Reinf. inactive responses2.43.26.11.5-1.7-1.6-2.31.6-1.61.5-1.5-0.72.51.9-2.1
Incentive salience index mean0.40.53.4-0.3-0.0-0.0-0.70.0-0.1-0.00.00.61.80.3-1.3
Condit. Reinf. lever presses0.20.43.0-0.40.10.1-0.4-0.1-0.10.1-0.10.21.70.4-0.9
Condit. Reinf. active minus inactive responses0.00.10.4-0.10.10.10.2-0.20.10.2-0.2-0.20.60.30.5
Condit. Reinf. active-inactive response ratio0.10.10.30.2-0.3-0.30.10.2-0.30.5-0.5-0.6-0.20.50.2
Condit. Reinf. active responses0.60.81.2-1.01.11.10.7-1.11.1-0.90.91.10.6-0.60.5
Condit. Reinf. inactive responses1.01.52.2-1.21.41.40.8-1.41.4-1.41.41.50.5-1.10.6
Condit. Reinf. lever presses0.91.32.7-1.31.21.11.5-1.31.2-1.01.00.3-0.1-0.91.6
Condit. Reinf. lever reinforcers received0.71.01.4-1.01.21.20.9-1.21.1-0.90.90.90.4-0.81.0
Conditioned reinforcement - actives0.31.02.2-0.81.41.51.3-1.11.5-0.40.41.3-0.2-0.40.0
Conditioned reinforcement - inactives0.10.30.9-0.40.70.50.5-0.70.7-0.20.20.9-0.1-0.2-0.3
Conditioned locomotion0.60.91.4-0.80.91.00.9-0.71.0-1.11.10.8-1.2-1.10.9
Patch foraging indifference point 0 sec0.00.10.30.20.10.10.20.2-0.20.2-0.2-0.50.20.10.5
Patch foraging indifference point AUC0.00.10.30.50.1-0.0-0.2-0.2-0.10.3-0.30.40.50.10.2
Delay disc. indifference point, 0s delay1.01.22.21.1-1.0-1.0-1.51.0-1.11.0-1.0-0.31.31.1-1.2
Delay disc. indifference point, 16s delay0.50.71.0-0.80.70.70.9-0.80.9-1.01.00.3-0.6-1.00.9
Delay disc. indifference point, 2s delay0.60.61.6-1.00.80.80.4-0.80.7-0.80.81.30.1-0.6-0.7
Delay disc. indifference point, 24s delay0.10.10.2-0.40.10.10.3-0.10.4-0.40.40.4-0.1-0.3-0.5
Delay disc. indifference point, 4s delay0.20.21.0-0.70.10.1-0.2-0.10.0-0.20.20.51.00.1-0.9
Delay disc. indifference point, 8s delay1.11.82.8-1.71.41.41.2-1.41.4-1.51.51.31.1-1.20.3
Indifference point function ln k0.00.10.5-0.70.10.10.4-0.10.1-0.20.2-0.40.1-0.10.1
Indifference point function log k0.00.10.5-0.70.10.10.4-0.10.1-0.20.2-0.40.1-0.10.1
Patch foraging total patch changes 0 sec0.00.10.70.10.40.40.5-0.20.2-0.10.1-0.3-0.3-0.20.9
Patch foraging total patch changes 12 sec0.20.31.21.1-0.1-0.2-0.00.3-0.50.6-0.6-0.6-0.20.21.0
Patch foraging total patch changes 18 sec0.20.41.50.00.70.50.8-0.50.4-0.20.20.1-0.9-0.41.2
Patch foraging total patch changes 24 sec0.10.40.80.9-0.5-0.6-0.80.7-0.60.6-0.6-0.30.80.6-0.3
Patch foraging total patch changes 6 sec1.22.03.01.7-1.3-1.3-1.61.5-1.51.5-1.5-1.11.31.4-0.7
Patch foraging time to switch 0 sec0.31.02.10.8-1.1-1.1-1.01.1-0.91.0-1.0-0.5-0.41.1-1.4
Patch foraging water rate 0 sec0.62.12.9-1.61.61.51.7-1.51.3-1.71.71.0-0.2-1.71.3
Patch foraging water rate 12 sec0.10.30.8-0.60.50.50.6-0.50.4-0.50.50.10.9-0.30.6
Patch foraging water rate 18 sec0.10.30.9-0.50.30.40.4-0.20.4-0.70.70.4-0.9-0.90.3
Patch foraging water rate 24 sec0.10.10.40.3-0.4-0.4-0.30.3-0.60.2-0.2-0.50.10.10.2
Patch foraging water rate 6 sec0.20.31.4-0.70.40.30.3-0.40.3-0.40.40.41.2-0.2-0.5
Seeking ratio, delayed vs. immediate footshock0.50.76.4-0.90.50.50.0-0.50.3-0.40.40.22.50.1-0.4
Distance traveled before self-admin0.20.42.0-0.1-0.3-0.3-0.30.3-0.30.4-0.4-0.11.40.7-1.3
Distance traveled after self-admin0.71.22.9-1.71.21.21.1-1.21.2-0.90.91.20.8-0.6-0.7
Extensor digitorum longus weight0.20.83.6-0.80.40.5-0.2-0.50.5-0.40.41.31.9-0.0-1.7
Bone: elastic displacement0.20.20.8-0.00.40.40.3-0.40.4-0.30.30.8-0.9-0.50.2
Bone: elastic work0.10.20.8-0.10.20.30.3-0.40.3-0.20.20.3-0.9-0.40.6
Bone: endosteal estimation0.51.14.3-1.70.70.70.4-0.70.7-0.60.60.92.10.0-1.6
Bone: endosteal perimeter0.30.72.2-1.30.50.60.4-0.40.6-0.40.40.81.5-0.0-1.4
Epididymis fat weight0.41.84.52.1-1.3-1.4-1.71.3-1.41.5-1.5-0.5-0.61.1-0.8
Delta time in closed arm before/after self-admin0.70.62.4-0.30.40.40.7-0.30.3-0.80.80.1-1.5-1.11.3
Delta time in open arm before/after self-admin3.64.26.62.3-2.1-2.1-1.71.9-2.02.6-2.6-2.30.82.5-0.6
Diff in mean of infusions in LGA sessions1.32.44.4-2.01.91.91.5-2.11.5-1.41.41.70.5-1.20.1
Delay discount exponential model param0.60.81.71.3-0.8-0.8-0.70.9-0.91.0-1.0-1.0-0.70.70.2
Extinction: sum of active levers before priming0.00.00.1-0.20.20.20.2-0.10.2-0.10.1-0.20.30.10.1
Active lever presses in extinction session 60.30.33.20.1-0.00.0-0.40.0-0.10.3-0.3-0.31.80.6-0.0
Bone: final force0.30.41.0-0.60.60.60.8-0.70.7-0.60.60.2-0.0-0.61.0
Bone: final moment0.40.61.6-0.70.80.81.0-0.80.8-0.70.70.2-0.6-0.81.3
Food consumed during 24 hour testing period3.16.29.7-3.12.72.72.9-2.72.7-2.72.72.1-0.5-2.51.4
Glucose0.10.10.50.3-0.4-0.4-0.30.4-0.30.3-0.3-0.1-0.00.3-0.7
Heart weight0.30.51.6-0.50.70.70.2-0.80.6-0.20.21.31.1-0.1-0.5
Delay discount hyperbolic model param0.81.02.01.4-1.0-1.0-0.71.1-1.01.1-1.1-1.2-0.50.80.3
Intermittent access intake day 1-15 change0.42.14.2-1.32.02.11.1-1.81.7-1.21.21.91.0-0.90.6
Intermittent access intake escalation0.31.73.5-1.11.81.91.0-1.61.5-1.01.01.61.1-0.80.7
Intermittent access intake escalation 21.11.83.2-1.41.71.80.9-1.41.5-1.11.11.51.8-0.70.2
Intermitt. access day 1 inactive lever presses0.00.41.5-0.4-0.1-0.20.3-0.1-0.0-0.70.7-0.6-0.8-0.91.2
Intermitt. access day 15 inactive lever presses0.00.10.20.2-0.2-0.4-0.50.0-0.30.2-0.20.20.30.0-0.3
Intermitt. access escalation Index1.75.48.0-2.12.72.62.6-2.82.7-2.12.12.8-1.9-2.00.2
Intermittent access day 1 total infusions0.10.32.1-0.20.30.30.4-0.30.3-0.10.10.6-1.5-0.3-0.5
Intermittent access day 15 total infusions0.30.81.9-0.81.21.10.7-1.01.0-0.60.61.4-0.5-0.5-0.3
Intermittent access terminal intake (last 3 days)1.01.83.2-1.61.71.71.1-1.41.4-1.31.31.8-0.4-1.2-0.2
Intermittent access total infusions0.50.60.9-0.80.90.90.8-0.70.8-0.60.60.8-0.9-0.6-0.1
Intermittent access day 1 locomotion0.40.73.4-0.60.60.60.4-0.60.6-0.70.70.9-1.9-0.90.0
Intermittent access day 15 total locomotion0.10.30.8-0.50.20.20.3-0.10.3-0.70.70.1-0.9-0.80.4
Intermittent access total locomotion0.70.81.8-1.30.80.80.8-0.70.9-1.21.20.6-0.5-1.00.4
Intermittent access standard deviation0.00.30.5-0.40.60.70.4-0.30.6-0.50.50.50.3-0.50.4
Left kidney weight1.08.210.7-3.13.33.23.0-3.23.1-3.03.02.7-1.1-2.91.9
Right kidney weight0.43.04.2-2.12.02.01.8-1.91.9-1.71.72.0-0.2-1.70.8
Cocaine induced anxiety0.10.32.60.0-0.1-0.3-0.5-0.0-0.10.4-0.40.5-0.40.5-1.6
Post-drug Anxiety0.80.91.41.0-1.1-1.1-0.80.9-0.81.1-1.1-0.5-0.11.1-1.2
Baseline Anxiety1.21.94.02.0-1.7-1.5-1.01.4-1.41.5-1.5-1.70.21.10.7
Tail length0.00.10.30.20.30.3-0.5-0.0-0.1-0.00.00.30.50.00.2
Length with tail0.31.54.0-1.01.61.60.8-1.41.2-1.01.02.0-0.2-1.0-0.0
Length without tail1.79.014.8-3.43.53.53.0-3.43.4-3.03.03.9-0.7-2.80.2
Times rat made contact with spout2.02.33.4-1.81.61.61.7-1.51.6-1.71.70.9-0.2-1.61.6
Lifetime Intake0.20.30.9-0.50.70.60.4-0.50.5-0.40.40.7-1.0-0.4-0.5
Liver weight, left1.01.73.0-1.11.71.71.2-1.71.5-1.11.11.7-0.6-1.00.4
Liver weight, right1.42.54.4-1.62.01.91.4-2.11.7-1.51.52.0-0.2-1.40.6
Locomotor activity0.40.61.0-0.50.70.81.0-0.90.9-0.70.70.8-0.9-0.80.6
Locomotor testing distance0.10.30.8-0.20.40.50.7-0.60.5-0.30.30.5-0.9-0.50.5
Locomotor testing rearing0.00.00.40.1-0.00.10.1-0.10.0-0.00.00.3-0.6-0.1-0.1
Locomotion in novel chamber0.20.21.0-0.3-0.3-0.3-0.30.3-0.4-0.10.1-0.90.5-0.01.0
Locomotion in novel chamber post-restriction0.10.20.70.20.30.30.1-0.30.10.4-0.40.8-0.60.1-0.7
Fecal boli incidents, locomotor time 10.51.43.3-1.31.21.20.7-1.11.4-1.31.31.80.1-0.9-1.1
Change in fecal boli incidents, locomotor task1.11.13.90.8-0.9-0.9-0.20.8-1.11.1-1.1-2.00.70.91.3
Time >=10cm from walls, locomotor time 10.20.22.0-0.50.10.1-0.1-0.1-0.0-0.00.00.50.40.1-1.4
Bouts of movement, locomotor time 10.30.40.7-0.50.60.60.6-0.50.5-0.70.70.30.3-0.80.8
Total resting periods, locomotor time 10.40.51.1-0.60.70.70.8-0.60.7-0.80.80.30.0-0.91.1
Rest time, locomotor task time 13.45.57.2-2.22.62.62.4-2.42.5-2.72.71.8-1.5-2.61.9
Distance moved, locomotor task time 10.61.72.51.6-1.4-1.4-1.51.2-1.41.5-1.5-0.80.71.4-1.0
Vertical activity count, locomotor time 10.21.11.51.2-1.2-1.2-1.21.1-1.11.1-1.1-0.80.61.1-0.6
Time >=10cm from walls, locomotor time 20.51.41.7-1.11.31.31.1-1.31.2-1.21.21.2-1.2-1.20.3
Bouts of movement, locomotor time 20.00.00.30.2-0.2-0.2-0.50.2-0.1-0.00.00.10.3-0.10.2
Total resting periods, locomotor time 20.00.00.10.1-0.1-0.1-0.30.1-0.0-0.10.10.00.3-0.20.4
Rest time, locomotor task time 20.40.73.1-0.00.40.40.7-0.30.5-0.50.5-0.3-1.5-0.81.8
Distance moved, locomotor task time 20.81.13.21.0-0.9-0.9-1.10.8-1.11.0-1.0-0.41.81.1-0.9
Vertical activity count, locomotor time 20.00.10.40.00.20.2-0.0-0.20.1-0.10.10.40.60.1-0.4
Light reinforcement 10.73.26.8-1.82.12.11.4-2.12.0-1.81.82.60.5-1.5-0.2
Light reinforcement 20.30.62.1-0.30.60.71.1-0.60.7-0.40.4-0.1-1.2-0.51.4
Bone: marrow area0.51.23.7-1.80.80.80.6-0.80.8-0.70.71.01.9-0.1-1.5
Bone: maximum diameter1.42.87.4-2.71.71.81.8-1.71.8-1.71.71.51.1-1.20.1
Bone: maximum force0.20.30.5-0.70.60.60.7-0.60.6-0.50.50.10.3-0.40.7
Bone: maximum moment0.30.51.1-0.80.70.70.9-0.70.8-0.60.60.2-0.2-0.61.0
Mean time between licks in bursts0.00.31.1-0.10.50.50.7-0.50.5-0.30.30.1-0.6-0.51.1
Mean num. licks in bursts0.51.43.8-0.61.01.01.3-0.91.0-1.01.00.3-1.6-1.32.0
Cd content in liver0.40.51.11.1-0.5-0.5-0.90.6-0.50.6-0.60.30.60.5-0.9
Co content in liver1.72.02.8-0.91.51.51.3-1.51.5-1.51.51.6-1.3-1.71.2
Cu content in liver0.30.30.5-0.60.60.60.7-0.60.6-0.50.50.6-0.5-0.60.3
Fe content in liver4.04.98.51.5-2.2-2.2-2.22.2-2.22.2-2.2-2.42.92.6-1.2
K content in liver0.00.00.2-0.1-0.2-0.2-0.10.2-0.20.2-0.2-0.10.30.1-0.4
Mg content in liver0.10.10.4-0.40.10.10.3-0.10.1-0.10.1-0.00.6-0.10.2
Mn content in liver0.50.51.3-0.70.50.51.1-0.50.5-0.50.5-0.2-1.1-0.61.1
Na content in liver2.22.55.50.7-1.6-1.6-1.61.5-1.61.5-1.5-1.12.31.8-1.7
Rb content in liver1.21.43.21.1-1.1-1.1-1.21.1-1.11.1-1.1-1.31.81.3-0.3
Se content in liver1.11.22.31.0-1.3-1.3-0.91.2-1.31.2-1.2-1.50.11.1-0.2
Sr content in liver0.30.30.60.5-0.5-0.5-0.50.5-0.50.5-0.5-0.30.80.5-0.5
Zn content in liver0.20.31.7-0.00.20.20.3-0.00.2-0.20.20.7-1.3-0.5-0.7
Bone: minimum diameter0.71.31.9-1.31.21.31.4-1.11.2-1.11.10.7-0.7-1.11.2
Time in familiar zone, hab. session 10.20.21.5-0.60.20.20.4-0.20.5-0.40.4-0.01.2-0.20.2
Time in novel zone, hab. session 10.70.83.5-0.30.80.80.7-0.80.7-0.70.70.9-1.9-1.00.4
Total zone transitions, hab. session 12.33.35.62.4-1.7-1.7-2.21.7-2.02.0-2.0-1.31.31.8-0.9
Total locomotion distance, hab. session 12.84.07.72.8-2.0-2.0-2.42.0-2.22.2-2.2-1.51.12.0-0.9
Locomotion velocity, hab. session 12.53.66.32.5-1.8-1.8-2.21.8-2.12.1-2.1-1.51.21.9-0.7
Time in familiar zone, hab. session 20.00.10.3-0.20.10.10.1-0.00.1-0.10.1-0.30.4-0.10.6
Time in novel zone, hab. session 20.20.20.7-0.40.30.30.6-0.30.4-0.40.40.5-0.8-0.5-0.2
Total zone transitions, hab. session 22.12.74.52.0-1.5-1.5-2.11.5-1.81.6-1.6-1.02.01.6-0.9
Total locomotion distance, hab. session 22.12.74.92.2-1.5-1.5-2.21.5-1.81.6-1.6-1.01.81.5-0.8
Locomotion velocity, hab. session 21.92.55.12.3-1.5-1.5-2.11.4-1.81.6-1.6-1.11.51.5-0.6
Novel to familiar place preference ratio0.60.81.2-1.01.11.10.8-1.10.9-0.90.91.00.1-0.70.3
Novelty place preference1.21.62.3-1.51.51.51.2-1.51.3-1.31.31.4-0.1-1.10.2
Time in novel zone, NPP test1.92.33.6-1.91.81.71.5-1.81.6-1.61.61.6-0.2-1.40.4
Total zone transitions, NPP test1.21.83.71.5-1.2-1.2-1.61.3-1.41.3-1.3-0.91.91.3-0.6
Total locomotion distance, NPP test1.82.64.51.7-1.5-1.5-2.11.5-1.71.5-1.5-0.92.11.6-1.2
Locomotion velocity, NPP test3.44.87.72.5-2.2-2.2-2.82.2-2.32.2-2.2-1.52.32.2-1.5
Intraocular pressure0.40.71.2-0.51.00.90.9-0.80.9-0.80.80.6-0.6-0.91.1
Delta distance traveled before/after self-admin3.43.84.9-2.12.22.22.0-2.12.2-2.02.02.0-1.1-1.90.9
Delta ambulatory time before/after self-admin2.54.35.4-2.22.32.32.3-2.22.3-2.22.21.9-1.4-2.11.3
Parametrial fat weight0.20.42.20.4-0.0-0.0-0.5-0.1-0.20.2-0.21.0-1.50.1-1.2
Pavlov. Cond. lever latency0.60.84.90.20.10.10.8-0.10.4-0.40.4-0.4-2.2-0.71.6
Pavlov. Cond. magazine entry latency0.20.31.50.3-0.2-0.2-0.70.2-0.40.4-0.40.30.60.5-1.2
Pavlov. Cond. change in total contacts0.20.21.2-0.10.20.2-0.4-0.2-0.10.0-0.00.70.80.1-1.1
Pavlov. Cond. index score0.50.62.80.3-0.3-0.3-1.00.3-0.60.6-0.60.31.40.7-1.7
Pavlov. Cond. latency score0.50.62.50.2-0.3-0.3-1.00.3-0.60.6-0.60.31.50.7-1.6
Pavlov. Cond. lever contacts0.40.52.5-0.40.10.1-0.5-0.1-0.20.1-0.10.61.60.3-1.5
Pavlov. Cond. magazine entry number0.20.31.1-0.50.30.30.8-0.30.5-0.50.5-0.1-0.6-0.51.1
Pavlov. Cond. intertrial magazine entries2.12.64.31.3-1.6-1.6-2.11.5-1.61.6-1.6-1.01.91.8-1.5
Pavlov. Cond. lever-magazine prob. diff.0.70.83.70.4-0.4-0.4-1.10.4-0.70.6-0.60.31.50.8-1.9
Pavlov. Cond. response bias0.40.52.70.2-0.2-0.2-0.80.2-0.40.3-0.30.51.10.5-1.7
Pavlov. Cond. lever latency0.50.71.41.2-0.8-0.8-0.91.0-0.80.7-0.7-0.4-1.10.4-0.8
Pavlov. Cond. magazine entry latency0.71.02.11.0-1.1-1.2-0.61.1-1.11.2-1.2-1.4-0.41.00.2
Pavlov. Cond. change in total contacts0.10.21.3-0.20.20.20.5-0.40.2-0.00.0-0.30.2-0.11.1
Pavlov. Cond. index score0.10.10.3-0.1-0.2-0.20.10.1-0.20.4-0.4-0.60.60.40.4
Pavlov. Cond. latency score0.10.20.5-0.2-0.2-0.20.30.0-0.10.3-0.3-0.70.70.30.7
Pavlov. Cond. lever contacts0.50.81.6-1.31.00.91.0-1.10.9-0.80.80.50.8-0.50.7
Pavlov. Cond. magazine entry number0.91.22.3-0.91.21.30.8-1.11.2-1.21.21.5-0.3-1.20.1
Pavlov. Cond. intertrial magazine entries0.20.40.8-0.60.40.60.0-0.40.6-0.90.90.70.6-0.6-0.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.0-0.2-0.20.10.1-0.20.3-0.3-0.60.60.40.5
Pavlov. Cond. response bias0.10.20.50.0-0.3-0.4-0.30.2-0.30.5-0.5-0.40.70.6-0.1
Time in closed arm before self-admin0.10.21.8-0.50.10.00.10.00.30.0-0.00.40.80.4-1.3
Time in closed arm after self-admin0.10.10.50.1-0.2-0.2-0.00.5-0.2-0.10.10.1-0.7-0.3-0.2
Time in open arm before self-admin2.32.84.5-2.11.71.81.5-1.71.5-2.12.11.0-0.1-1.91.6
Time in open arm after self-admin0.40.41.20.2-0.4-0.4-0.40.3-0.50.7-0.7-1.11.00.9-0.1
Bone: periosteal estimation0.51.13.4-1.81.11.11.1-1.11.1-1.01.00.90.9-0.6-0.2
Bone: periosteal perimeter0.10.20.7-0.90.30.30.6-0.30.3-0.20.20.10.5-0.0-0.3
Bone: post-yield work0.20.43.3-0.80.20.1-0.1-0.20.1-0.00.00.21.80.4-0.8
Progressive ratio test 1 active lever presses1.01.82.6-1.41.41.21.4-1.41.4-1.31.31.4-1.6-1.30.2
Progressive ratio test 1 breakpoint1.12.02.6-1.51.41.21.6-1.51.5-1.51.51.4-1.6-1.40.3
Progressive ratio test 1 inactive lever presses0.20.61.5-0.60.60.50.9-0.70.7-0.60.60.3-1.2-0.81.0
Progressive ratio test 2 active lever presses0.71.01.7-0.91.21.21.3-1.11.3-0.80.81.0-0.6-0.80.8
Progressive ratio test 2 breakpoint0.60.81.3-0.71.11.11.1-0.91.2-0.60.60.9-0.6-0.70.7
Progressive ratio test 2 inactive lever presses0.10.20.8-0.40.30.20.3-0.30.3-0.30.30.4-0.9-0.40.1
Incentive Sensitization - Responses0.20.51.6-0.60.80.80.7-0.60.7-0.60.60.3-0.0-0.61.3
Incentive Sensitization - Breakpoint0.20.41.4-0.40.70.70.5-0.50.6-0.50.50.3-0.0-0.61.2
Sum of active levers in priming session hrs 5-60.10.10.7-0.20.30.3-0.0-0.30.20.1-0.1-0.00.80.3-0.1
Progressive ratio0.30.91.8-1.21.11.10.4-1.00.9-1.11.11.30.2-0.8-0.6
Food seeking constrained by brief footshock1.41.83.9-2.01.31.31.4-1.41.5-1.41.41.21.1-1.0-0.0
Seeking ratio, punishment vs. effort0.20.41.00.2-0.6-0.6-0.10.7-0.40.6-0.6-0.81.00.70.1
Retroperitoneal fat weight0.10.72.71.6-0.2-0.3-0.80.1-0.50.8-0.80.6-1.70.3-0.1
Reaction time number correct0.31.21.70.9-1.2-1.2-1.21.1-1.11.1-1.1-0.81.21.3-1.3
Reaction time mean minus median0.00.21.40.60.30.20.2-0.10.10.4-0.40.2-1.20.10.4
Reaction time mean minus median AUC0.00.20.90.70.10.00.00.1-0.10.6-0.6-0.0-0.90.30.1
Reaction time num false alarms0.71.21.81.3-1.1-1.2-1.01.3-1.31.1-1.1-1.1-0.20.9-0.4
Reaction time num false alarms AUC0.81.72.61.5-1.4-1.5-1.21.6-1.61.4-1.4-1.4-0.21.1-0.6
Reaction time trials correct on left0.31.21.70.9-1.2-1.2-1.21.1-1.11.1-1.1-0.81.21.3-1.3
Reaction time trials on left0.41.51.91.0-1.3-1.3-1.31.2-1.21.2-1.2-0.91.21.4-1.4
Reaction time mean0.10.31.80.40.40.30.5-0.40.20.1-0.1-0.0-1.3-0.20.9
Reaction time mean AUC0.10.20.90.30.30.30.4-0.30.20.2-0.2-0.0-1.0-0.00.7
Median of all reaction times0.20.31.60.30.40.30.5-0.40.2-0.00.0-0.1-1.3-0.31.0
Reaction time omissions2.33.86.62.6-2.1-2.2-1.92.2-2.12.2-2.2-1.7-0.51.9-0.9
Reaction time false alarm rate0.30.41.00.9-0.6-0.7-0.40.8-0.70.6-0.6-0.7-1.00.20.2
Reaction time premature initiation rate0.30.51.8-0.60.70.80.3-0.70.7-0.60.61.3-0.4-0.5-0.7
Reaction time premature initiations0.10.21.4-0.10.20.2-0.2-0.20.2-0.00.00.90.10.1-1.2
Std. dev. reaction times0.10.41.71.0-0.0-0.1-0.10.2-0.30.8-0.8-0.3-1.30.40.3
Reaction time trials completed0.41.51.91.0-1.3-1.3-1.31.2-1.21.2-1.2-0.91.21.4-1.4
Reaction time trials AUC0.41.51.91.0-1.3-1.3-1.31.2-1.21.2-1.2-1.01.31.4-1.4
Run reversals in cocaine runway, females0.20.21.50.0-0.2-0.20.30.2-0.0-0.00.0-0.3-1.2-0.30.9
Run reversals in cocaine runway, males0.40.52.80.1-0.6-0.6-0.50.6-0.40.3-0.3-0.21.70.4-0.9
Latency to leave start box in cocaine runway0.60.92.10.7-0.9-0.9-0.50.8-0.71.0-1.0-1.41.51.00.6
Latency to leave start box in cocaine runway, F0.20.20.90.2-0.2-0.2-0.00.2-0.00.4-0.4-0.60.90.41.0
Latency to leave start box in cocaine runway, M1.21.22.40.9-1.1-1.1-0.81.0-1.11.2-1.2-1.61.11.1-0.1
Std. dev. time between licks in bursts0.40.83.60.6-0.6-0.6-0.70.6-0.60.9-0.9-0.71.91.0-0.0
Total sessions with >9 infusions0.40.50.9-1.00.70.60.4-0.60.5-0.90.90.7-0.7-0.7-0.3
Short access day 1 total inactive lever presses1.22.54.3-1.41.51.51.6-1.41.5-1.71.70.8-1.4-1.82.1
Short access day 10 total inactive lever presses0.00.10.4-0.10.30.30.1-0.20.2-0.20.20.20.0-0.30.6
Short access day 1 total infusions0.10.20.5-0.40.40.30.1-0.50.2-0.30.30.6-0.5-0.2-0.7
Short access day 10 total infusions0.10.21.8-0.2-0.0-0.10.20.3-0.10.0-0.0-0.1-1.40.0-0.8
Short access total infusions0.20.31.8-0.00.20.0-0.1-0.1-0.00.1-0.10.4-1.30.1-1.0
Short access day 1 locomotion0.81.32.8-1.41.31.20.9-1.21.2-1.11.11.7-0.1-1.0-0.6
Short access day 10 total locomotion0.00.20.6-0.6-0.4-0.3-0.10.4-0.2-0.60.6-0.80.2-0.40.4
Short access total locomotion0.60.92.0-1.30.70.60.7-0.70.7-1.41.40.4-1.1-1.30.5
One hour access (0.3 mA shock)0.30.30.6-0.70.60.60.7-0.40.6-0.50.50.8-0.5-0.6-0.2
Compulsive drug intake0.20.31.4-0.50.30.30.8-0.40.2-0.30.3-0.6-0.7-0.31.2
One hour access (shock baseline)0.10.11.2-0.1-0.0-0.1-0.40.3-0.10.1-0.10.40.40.1-1.1
Social response proportion1.11.38.10.10.60.61.3-0.60.8-0.50.5-0.6-1.8-0.92.8
Social responses0.20.31.4-0.20.40.40.6-0.50.5-0.50.50.0-0.6-0.61.2
Social time0.10.10.60.3-0.1-0.00.2-0.00.00.3-0.3-0.4-0.30.20.7
Soleus weight1.23.512.6-2.71.51.50.8-1.51.5-1.51.52.13.6-0.8-1.6
Bone: stiffness0.20.40.80.5-0.6-0.6-0.60.6-0.50.6-0.6-0.70.90.7-0.1
Tibialis anterior weight0.51.65.9-1.80.70.70.3-0.70.7-0.70.71.32.4-0.1-2.2
Time to tail flick, vehicle, before self-admin0.20.30.90.6-0.2-0.2-0.70.4-0.20.8-0.80.00.20.9-0.6
Time to tail flick, vehicle, after self-admin0.10.21.0-0.9-0.2-0.20.20.3-0.2-0.30.3-0.61.0-0.1-0.3
Time to tail flick, test, before self-admin0.10.10.3-0.10.10.20.1-0.20.2-0.40.40.6-0.0-0.5-0.2
Time to tail flick, test, after self-admin1.51.62.4-1.31.41.50.9-1.51.4-1.51.51.6-0.3-1.20.1
Delta time to tail flick, vehicle, before/after SA0.40.42.2-0.3-0.7-0.7-0.10.6-0.70.1-0.1-0.91.50.2-0.4
Delta time to tail flick, test, before/after SA1.01.21.6-1.21.31.31.3-1.21.3-1.11.10.7-0.6-0.90.8
Tibia length3.28.911.3-3.43.13.23.3-3.23.2-3.23.22.3-1.7-3.12.3
Ambulatory time before self-admin0.31.02.70.4-0.9-0.9-0.90.8-0.80.9-0.9-0.41.51.1-1.6
Ambulatory time after self-admin0.91.43.4-1.81.31.31.3-1.31.3-1.11.11.20.5-0.8-0.3
Bone: tissue strength0.20.21.70.40.0-0.10.20.1-0.00.1-0.1-0.7-0.7-0.11.3
Total heroin consumption0.70.91.8-0.91.11.20.6-1.31.0-0.80.80.71.3-0.40.6
Bone: trabecular number1.52.84.21.4-1.7-1.7-2.01.7-1.71.7-1.7-1.01.31.9-1.9
Bone: trabecular spacing0.20.42.50.50.20.20.4-0.20.2-0.10.1-0.2-1.0-0.51.6
Bone: trabecular thickness0.60.81.2-1.00.90.91.0-0.90.9-1.01.00.8-1.1-1.00.6
Bone: trabecular tissue density1.32.23.8-1.11.51.52.0-1.51.5-1.31.30.9-1.6-1.61.7
Water consumed over 24 hours1.01.93.7-1.91.41.41.5-1.41.4-1.61.61.00.3-1.40.9
Number of responses in last shaping day2.93.76.2-2.42.32.21.5-2.31.8-2.02.02.5-0.1-1.6-1.1