Hub : Genes

Gfm1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Gfm1 0.24 0.11 0.0e+00 0.13 0.14 0.15 0.15 4.2e-14 4.9e-15 2.2e-16 4.2e-16
2 Brain gene expression Gfm1 0.15 0.07 1.2e-15 0.15 0.16 0.17 0.15 3.1e-14 6.0e-15 1.6e-15 3.1e-14
3 PL gene expression Gfm1 0.15 0.06 0.0e+00 0.16 0.15 0.16 0.16 2.6e-17 1.7e-16 1.4e-16 9.3e-17
4 Brain mRNA stability Gfm1 0.39 0.12 0.0e+00 0.44 0.44 0.44 0.44 1.3e-44 7.0e-45 1.3e-44 9.9e-45
5 OFC mRNA stability Gfm1 0.24 0.14 8.0e-03 -0.01 -0.01 -0.01 -0.01 6.0e-01 8.2e-01 9.6e-01 9.6e-01
6 pVTA gene expression Gfm1 0.16 0.06 0.0e+00 0.23 0.22 0.21 0.22 2.8e-18 3.7e-17 4.1e-17 6.0e-18
7 PL mRNA stability Gfm1 0.35 0.13 0.0e+00 0.3 0.29 0.29 0.3 1.4e-33 2.3e-32 8.2e-32 1.0e-32
8 NAcc mRNA stability Gfm1 0.08 0.04 2.7e-14 0.11 0.1 0.1 0.1 5.5e-16 1.7e-15 6.9e-15 3.2e-15
9 BLA gene expression Gfm1 0.16 0.09 5.3e-05 0.04 0.03 0.04 0.04 5.3e-03 9.3e-03 3.0e-03 3.9e-03
10 Adipose intron excision ratio chr2_154014052_154016295 0.08 0.05 2.4e-07 0.07 0.06 0.05 0.07 3.7e-08 3.0e-07 1.7e-06 7.0e-08
11 pVTA mRNA stability Gfm1 0.16 0.07 5.6e-17 0.23 0.21 0.22 0.22 3.1e-18 1.9e-16 3.2e-17 2.3e-17
12 NAcc gene expression Gfm1 0.08 0.04 2.3e-15 0.11 0.1 0.11 0.12 1.5e-16 1.5e-15 7.0e-17 4.7e-17
13 BLA mRNA stability Gfm1 0.14 0.07 1.3e-05 0.11 0.09 0.1 0.11 1.6e-06 1.6e-05 9.9e-06 1.3e-06
14 IL mRNA stability Gfm1 0.19 0.11 6.6e-03 0.1 0.08 0.04 0.08 2.5e-03 7.1e-03 3.1e-02 5.3e-03
15 LHb gene expression Gfm1 0.23 0.12 8.3e-04 0.16 0.12 0.12 0.12 1.3e-04 1.0e-03 7.7e-04 7.8e-04
16 LHb mRNA stability Gfm1 0.63 0.14 2.0e-12 0.47 0.47 0.47 0.46 8.4e-13 7.4e-13 1.1e-12 2.9e-12
17 Liver gene expression Gfm1 0.2 0.1 1.1e-16 0.14 0.15 0.14 0.14 4.5e-15 3.2e-16 1.2e-15 2.5e-15
18 IC mRNA stability Gfm1 0.08 0.05 3.9e-04 0.08 0.07 0.06 0.05 3.7e-04 8.7e-04 2.0e-03 2.6e-03
19 Liver intron excision ratio chr2_154033738_154036228 0.07 0.04 1.1e-05 0.04 0.04 0.04 0.04 4.1e-05 2.0e-05 6.2e-05 3.2e-05
20 Liver intron excision ratio chr2_154036365_154037496 0.06 0.04 2.2e-05 0.04 0.04 0.04 0.04 6.6e-05 3.0e-05 7.3e-05 4.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.83.025.4-5.02.31.51.91.51.51.51.41.41.31.41.41.21.11.10.40.11.5-0.90.6
Area under the delay curve0.10.20.5-0.2-0.2-0.5-0.5-0.5-0.5-0.4-0.5-0.4-0.3-0.5-0.30.20.60.6-0.4-0.3-0.70.0-0.1
BMI with tail1.03.35.30.2-1.8-2.0-2.1-2.3-2.0-1.9-1.9-2.2-1.9-2.3-1.9-1.8-1.5-1.5-1.9-1.7-1.81.1-1.2
BMI without tail0.20.63.6-1.8-0.6-0.5-0.8-0.6-0.4-0.3-0.4-0.3-0.3-0.5-0.30.10.20.2-0.4-0.0-1.9-1.11.0
Body weight0.62.74.40.6-1.6-2.0-2.0-1.9-2.0-1.9-1.9-1.9-1.5-1.9-1.8-1.4-1.3-1.3-1.5-1.3-2.10.8-0.9
Weight adjusted by age0.20.22.1-1.40.1-0.5-0.3-0.5-0.5-0.5-0.6-0.50.2-0.4-0.3-0.0-0.2-0.2-0.5-0.5-0.50.1-0.2
Bone surface0.61.111.6-3.40.3-0.4-0.0-0.4-0.4-0.4-0.5-0.5-0.6-0.5-0.5-0.7-0.7-0.7-1.3-1.50.30.9-1.1
Bone volume0.71.217.7-4.21.20.40.90.40.40.40.30.30.20.30.30.1-0.0-0.0-0.7-1.01.10.4-0.6
Breakpoint value in progressive ratio session0.10.10.60.8-0.5-0.2-0.4-0.0-0.1-0.2-0.1-0.2-0.3-0.3-0.3-0.6-0.6-0.6-0.2-0.1-0.20.2-0.2
Number of licking bursts0.30.43.2-1.80.1-0.4-0.2-0.1-0.4-0.4-0.4-0.3-0.5-0.3-0.5-0.7-0.5-0.5-1.0-1.10.00.6-0.7
Context. condit. distance diff. score2.93.55.0-2.21.82.02.01.92.02.02.01.91.71.82.02.02.02.01.61.51.4-1.71.7
Locomotion velocity, session 10.10.10.30.10.10.40.30.60.40.40.40.50.40.50.40.30.20.20.40.40.3-0.30.3
Locomotion distance, session 10.70.91.61.2-0.8-0.9-0.8-0.9-0.9-0.9-0.9-1.0-0.8-0.9-1.0-1.2-1.1-1.1-0.8-0.9-0.01.2-1.2
Locomotion velocity, session 20.10.10.8-0.50.1-0.00.20.3-0.0-0.0-0.00.1-0.10.2-0.1-0.3-0.2-0.2-0.2-0.50.90.8-0.8
Locomotion distance, session 21.82.53.71.7-1.4-1.5-1.4-1.6-1.5-1.6-1.5-1.7-1.4-1.6-1.6-1.8-1.8-1.8-1.4-1.5-0.31.9-1.8
Locomotion velocity, session 31.11.22.3-1.0-0.9-1.0-0.8-0.9-1.0-1.0-1.0-1.0-0.9-1.0-1.1-1.4-1.4-1.4-1.4-1.5-0.41.2-1.3
Locomotion distance, session 30.30.34.4-2.10.50.40.50.40.40.30.40.30.50.30.30.10.10.1-0.2-0.30.4-0.10.0
Stereotopy head waving bouts, day 30.10.21.7-1.30.40.30.40.20.30.30.30.20.20.20.30.20.20.2-0.1-0.20.60.1-0.2
Stereotopy head waving duration, day 30.20.32.4-1.60.50.40.50.30.40.40.40.30.30.40.40.40.50.50.0-0.20.80.1-0.1
Locomotion velocity, session 70.20.21.81.4-0.4-0.2-0.2-0.2-0.2-0.2-0.2-0.4-0.2-0.5-0.2-0.3-0.3-0.3-0.0-0.10.30.5-0.4
Locomotion distance, session 71.01.32.10.61.01.21.11.11.21.31.21.11.21.11.10.90.90.91.41.40.8-1.11.2
Stereotopy head waving bouts, day 70.91.02.1-0.0-0.8-1.1-0.9-0.8-1.1-1.1-1.1-1.0-1.0-1.0-1.0-0.7-0.7-0.7-1.2-1.4-0.21.4-1.4
Stereotopy head waving duration, day 72.42.84.30.1-1.5-1.9-1.7-1.5-1.9-1.9-1.9-1.7-1.7-1.7-1.8-1.5-1.4-1.4-2.0-2.1-0.82.0-2.1
Locomotion velocity, session 80.50.60.90.4-0.7-0.9-0.9-0.7-0.9-0.9-0.9-0.7-0.9-0.7-0.8-0.8-0.7-0.7-0.8-0.8-0.70.6-0.6
Locomotion distance, session 80.10.10.40.6-0.2-0.1-0.1-0.2-0.1-0.2-0.1-0.3-0.3-0.3-0.3-0.5-0.6-0.6-0.2-0.30.30.5-0.5
Degree of sensitization distance0.80.97.02.60.30.60.30.50.60.70.60.60.60.60.60.70.70.71.31.40.0-0.91.0
Degree of sensitization stereotypy0.70.81.80.6-0.8-1.0-0.8-0.6-1.0-1.0-1.0-0.8-0.8-0.9-0.9-0.7-0.7-0.7-0.9-1.1-0.11.3-1.3
Conditioned locomotion0.50.61.0-0.1-0.4-0.8-0.8-0.6-0.8-0.9-0.8-0.7-0.9-0.8-0.8-0.8-0.6-0.6-0.9-1.0-0.50.8-0.9
Cocaine response after cond. corrected0.60.72.11.20.70.50.20.60.50.60.50.70.60.50.60.70.80.81.01.3-0.8-1.41.5
Cocaine response after cond. not corrected0.20.31.81.3-0.1-0.3-0.5-0.1-0.3-0.2-0.3-0.1-0.2-0.3-0.3-0.3-0.2-0.20.10.5-1.3-0.60.7
Cocaine response before conditioning0.60.71.5-0.9-0.9-0.8-0.7-0.7-0.8-0.8-0.8-0.7-0.8-0.6-0.9-1.1-1.2-1.2-1.1-1.0-0.50.8-0.8
Saline control response2.22.94.3-0.9-1.3-1.7-1.6-1.7-1.7-1.8-1.7-1.7-1.7-1.7-1.8-1.8-2.1-2.1-2.1-1.9-1.51.3-1.4
Bone: connectivity density0.71.112.7-3.61.40.81.00.70.80.80.70.70.50.70.70.50.60.60.0-0.10.5-0.60.4
Bone: cortical apparent density6.99.411.1-0.73.33.33.03.33.33.23.33.33.03.23.23.13.13.13.33.32.0-3.03.1
Bone: cortical area0.91.46.8-2.6-0.6-1.0-0.7-0.9-1.0-1.1-1.0-1.0-1.0-1.1-1.0-0.9-0.9-0.9-1.6-1.7-0.31.1-1.3
Bone: cortical porosity3.13.44.21.5-2.0-2.0-1.8-1.6-2.0-2.0-1.9-1.7-1.9-1.6-2.0-2.0-1.9-1.9-1.7-1.7-1.02.0-1.9
Bone: cortical porosity4.04.35.31.2-2.2-2.3-2.1-1.9-2.3-2.3-2.2-2.0-2.2-1.9-2.3-2.3-2.1-2.1-2.0-2.1-1.22.2-2.2
Bone: cortical thickness0.30.45.6-2.40.70.40.60.50.40.40.40.40.40.30.40.40.50.50.0-0.20.6-0.20.1
Bone: cortical thickness0.50.68.4-2.90.3-0.3-0.1-0.3-0.3-0.4-0.4-0.3-0.3-0.2-0.3-0.2-0.2-0.2-0.9-1.0-0.20.4-0.6
Bone: cortical tissue density6.79.110.8-0.63.23.23.03.33.23.23.23.33.03.23.23.03.03.03.33.31.9-3.03.1
Condit. Reinf. active minus inactive responses3.74.15.31.8-2.3-2.1-2.2-2.2-2.1-2.1-2.1-2.1-2.3-2.1-2.2-2.2-2.1-2.1-1.8-1.6-1.91.5-1.4
Condit. Reinf. active-inactive response ratio3.74.04.81.8-2.1-2.1-2.1-2.1-2.1-2.1-2.1-2.2-2.2-2.1-2.1-2.0-1.9-1.9-1.9-1.8-1.41.9-1.8
Condit. Reinf. active responses5.36.58.22.4-2.8-2.6-2.8-2.8-2.6-2.6-2.6-2.8-2.9-2.8-2.7-2.8-2.6-2.6-2.3-2.0-2.61.7-1.7
Condit. Reinf. inactive responses0.60.72.81.4-0.8-0.6-1.0-0.9-0.6-0.6-0.6-0.8-0.8-0.9-0.7-0.9-0.7-0.7-0.40.0-1.7-0.40.4
Incentive salience index mean2.22.74.32.1-2.0-1.6-1.7-1.7-1.6-1.6-1.6-1.7-1.9-1.8-1.7-1.8-1.8-1.8-1.3-1.1-1.41.2-1.1
Condit. Reinf. lever presses0.50.64.02.0-1.1-0.5-0.7-0.7-0.5-0.5-0.5-0.8-0.9-0.8-0.6-0.9-0.9-0.9-0.3-0.2-0.40.5-0.4
Condit. Reinf. active minus inactive responses0.60.81.4-0.4-0.6-0.9-1.0-1.2-0.9-1.0-0.9-1.1-0.8-1.1-0.9-0.7-0.8-0.8-1.1-0.9-1.10.4-0.5
Condit. Reinf. active-inactive response ratio0.10.20.9-0.40.10.2-0.1-0.20.20.10.2-0.00.1-0.10.20.20.00.00.10.5-0.9-1.00.9
Condit. Reinf. active responses1.31.82.8-0.4-1.0-1.4-1.2-1.5-1.4-1.4-1.4-1.5-1.3-1.4-1.4-1.3-1.5-1.5-1.6-1.7-0.61.4-1.5
Condit. Reinf. inactive responses1.11.53.20.0-0.8-1.2-0.8-1.1-1.2-1.2-1.2-1.2-1.0-1.1-1.2-1.2-1.2-1.2-1.4-1.60.21.8-1.8
Condit. Reinf. lever presses3.14.35.81.2-2.4-2.2-2.2-2.1-2.2-2.2-2.2-2.1-2.1-2.1-2.2-2.2-2.4-2.4-2.0-1.8-2.01.6-1.6
Condit. Reinf. lever reinforcers received1.01.42.3-0.4-0.9-1.2-1.0-1.4-1.2-1.2-1.2-1.4-1.1-1.3-1.2-1.1-1.3-1.3-1.5-1.5-0.51.3-1.4
Conditioned reinforcement - actives0.10.10.20.30.10.40.30.30.50.20.50.30.30.30.50.40.10.10.50.50.2-0.30.3
Conditioned reinforcement - inactives0.50.71.21.1-1.0-0.9-0.9-0.8-0.8-0.9-0.9-0.8-0.6-0.8-0.9-1.1-0.9-0.9-0.4-0.3-0.90.3-0.3
Conditioned locomotion0.20.21.00.31.0-0.00.50.10.2-0.10.20.01.00.10.40.70.60.60.50.30.3-0.10.1
Patch foraging indifference point 0 sec0.30.52.1-1.51.10.60.80.00.70.50.70.21.10.30.70.80.70.70.30.20.6-0.40.4
Patch foraging indifference point AUC0.30.51.71.3-1.0-0.5-0.6-0.6-0.5-0.5-0.5-0.7-0.7-0.8-0.6-0.8-0.8-0.8-0.4-0.4-0.20.7-0.6
Delay disc. indifference point, 0s delay0.30.41.8-0.80.6-0.40.1-0.2-0.3-0.1-0.3-0.3-0.0-0.2-0.20.00.10.1-0.9-1.20.61.3-1.3
Delay disc. indifference point, 16s delay0.50.52.2-0.0-0.20.70.10.40.50.50.50.60.10.40.50.40.60.60.81.1-0.7-1.51.5
Delay disc. indifference point, 2s delay0.70.82.2-0.50.1-1.1-0.5-0.9-0.9-0.9-0.9-1.0-0.6-0.9-0.7-0.3-0.1-0.1-1.2-1.5-0.11.4-1.5
Delay disc. indifference point, 24s delay0.30.31.40.3-0.60.0-0.20.10.10.10.10.30.20.10.20.50.70.70.60.9-0.8-1.21.2
Delay disc. indifference point, 4s delay0.30.31.1-0.8-0.0-0.6-0.5-0.5-0.6-0.4-0.6-0.5-0.5-0.5-0.5-0.2-0.1-0.1-0.9-1.0-0.30.8-0.8
Delay disc. indifference point, 8s delay0.10.20.90.10.1-0.4-0.3-0.3-0.3-0.3-0.3-0.30.2-0.3-0.00.61.01.0-0.0-0.0-0.5-0.10.1
Indifference point function ln k0.20.41.1-0.41.10.70.80.20.70.70.70.40.70.70.70.60.60.60.50.40.9-0.40.3
Indifference point function log k0.20.41.1-0.41.10.70.80.20.70.70.70.40.70.70.70.60.60.60.50.40.9-0.40.3
Patch foraging total patch changes 0 sec0.20.41.6-1.30.90.50.70.00.60.50.60.11.00.20.60.70.60.60.30.20.4-0.40.4
Patch foraging total patch changes 12 sec0.30.30.6-0.70.40.60.50.60.60.60.60.60.60.40.60.50.60.60.50.50.2-0.70.6
Patch foraging total patch changes 18 sec0.10.11.4-1.2-0.2-0.10.0-0.2-0.0-0.1-0.0-0.1-0.0-0.3-0.0-0.10.10.1-0.2-0.2-0.4-0.10.1
Patch foraging total patch changes 24 sec0.10.11.7-1.3-0.30.10.2-0.10.1-0.10.1-0.10.3-0.20.0-0.2-0.1-0.1-0.3-0.40.30.2-0.3
Patch foraging total patch changes 6 sec0.10.20.6-0.4-0.1-0.5-0.2-0.8-0.4-0.5-0.4-0.6-0.3-0.7-0.4-0.4-0.5-0.5-0.5-0.5-0.30.3-0.4
Patch foraging time to switch 0 sec0.51.12.3-1.20.70.70.61.30.81.00.81.40.61.20.80.91.11.10.91.1-0.3-1.51.5
Patch foraging water rate 0 sec0.61.22.01.2-1.0-1.0-1.0-1.3-1.0-1.1-1.0-1.4-0.8-1.4-1.1-1.2-1.2-1.2-1.0-0.8-0.80.8-0.8
Patch foraging water rate 12 sec0.10.32.3-1.50.70.50.70.70.50.40.50.50.40.60.40.20.00.00.1-0.00.6-0.10.0
Patch foraging water rate 18 sec0.20.20.60.6-0.0-0.4-0.3-0.6-0.5-0.6-0.5-0.8-0.0-0.7-0.3-0.0-0.1-0.1-0.5-0.60.00.7-0.7
Patch foraging water rate 24 sec0.20.20.6-0.80.70.60.70.60.60.60.60.40.50.50.50.20.00.00.10.00.7-0.10.1
Patch foraging water rate 6 sec0.40.51.9-1.4-0.4-0.4-0.3-0.3-0.4-0.5-0.4-0.5-0.5-0.4-0.5-0.9-1.0-1.0-1.0-1.10.10.9-1.0
Seeking ratio, delayed vs. immediate footshock1.62.02.7-1.11.51.41.41.51.31.41.31.51.41.41.41.61.61.61.51.40.6-1.51.5
Distance traveled before self-admin0.20.20.40.60.20.30.30.60.30.50.30.60.40.50.20.10.50.50.70.70.2-0.40.5
Distance traveled after self-admin1.21.53.0-0.21.11.21.41.71.21.21.21.61.11.41.10.80.90.91.51.50.8-1.21.2
Extensor digitorum longus weight3.513.718.03.2-3.7-3.9-3.9-4.2-3.9-3.9-3.9-4.2-3.7-4.2-3.8-3.6-3.5-3.5-3.6-3.4-2.63.4-3.4
Bone: elastic displacement0.30.41.0-1.0-0.7-0.4-0.2-0.6-0.4-0.4-0.4-0.6-0.5-0.6-0.4-0.5-0.5-0.5-0.8-0.90.50.9-0.9
Bone: elastic work1.01.43.9-2.0-0.6-0.9-0.4-0.9-0.9-0.9-0.9-1.1-0.9-1.1-0.9-0.8-0.8-0.8-1.5-1.90.71.7-1.8
Bone: endosteal estimation1.43.04.5-1.0-1.4-1.8-1.5-1.9-1.8-1.8-1.8-1.9-1.5-1.8-1.8-1.6-1.8-1.8-2.1-2.1-1.11.6-1.7
Bone: endosteal perimeter1.42.95.2-1.5-1.3-1.7-1.4-1.7-1.7-1.7-1.8-1.7-1.7-1.6-1.7-1.5-1.7-1.7-2.2-2.3-0.81.8-1.9
Epididymis fat weight0.31.02.4-1.00.70.60.50.80.80.80.80.90.90.70.80.91.41.41.01.2-0.3-1.61.5
Delta time in closed arm before/after self-admin0.20.20.6-0.0-0.5-0.3-0.2-0.0-0.3-0.1-0.3-0.0-0.70.0-0.4-0.7-0.8-0.8-0.3-0.2-0.00.2-0.2
Delta time in open arm before/after self-admin0.20.20.70.30.70.50.2-0.10.30.00.4-0.20.6-0.10.40.60.60.6-0.1-0.40.80.7-0.7
Diff in mean of infusions in LGA sessions0.60.71.30.3-0.8-0.9-1.0-1.0-0.8-1.1-0.8-1.1-0.5-1.2-0.7-0.5-0.2-0.2-0.9-0.9-0.60.9-0.9
Delay discount exponential model param0.30.30.80.00.40.70.70.70.70.60.70.60.40.70.5-0.0-0.3-0.30.50.40.9-0.20.2
Extinction: sum of active levers before priming1.01.22.91.7-0.8-1.3-1.2-1.1-1.4-1.3-1.4-1.3-0.6-1.5-1.1-0.5-0.1-0.1-0.7-0.6-1.30.8-0.7
Active lever presses in extinction session 60.10.10.40.1-0.1-0.4-0.30.1-0.4-0.3-0.3-0.1-0.3-0.4-0.4-0.6-0.3-0.3-0.2-0.0-0.7-0.20.2
Bone: final force1.21.97.7-2.8-0.3-1.2-0.7-1.1-1.2-1.2-1.2-1.3-0.8-1.2-1.1-0.9-0.8-0.8-1.9-2.20.21.7-1.9
Bone: final moment1.11.78.7-2.9-0.2-1.1-0.5-1.0-1.1-1.1-1.1-1.2-0.7-1.2-1.0-0.9-0.7-0.7-1.8-2.10.51.7-1.9
Food consumed during 24 hour testing period0.60.81.50.30.61.00.80.61.01.01.00.71.00.81.00.90.90.91.11.20.3-1.11.2
Glucose0.30.44.0-1.2-0.2-0.3-0.60.1-0.3-0.3-0.30.2-0.40.1-0.3-0.2-0.1-0.1-0.20.2-2.0-1.11.0
Heart weight0.20.31.70.2-0.2-0.5-0.7-0.7-0.4-0.5-0.4-0.6-0.3-0.6-0.3-0.1-0.0-0.0-0.10.1-1.3-0.50.5
Delay discount hyperbolic model param0.30.40.90.10.40.80.80.80.80.70.80.70.50.80.50.0-0.3-0.30.70.60.9-0.30.3
Intermittent access intake day 1-15 change0.20.41.01.0-0.5-0.3-0.7-0.7-0.5-0.7-0.5-0.6-1.0-0.7-0.6-0.8-0.6-0.6-0.5-0.4-0.60.3-0.3
Intermittent access intake escalation0.10.20.70.8-0.2-0.2-0.6-0.5-0.4-0.6-0.4-0.5-0.8-0.5-0.5-0.5-0.4-0.4-0.4-0.3-0.40.3-0.3
Intermittent access intake escalation 20.00.00.10.40.30.2-0.00.00.0-0.00.10.1-0.20.0-0.0-0.1-0.1-0.10.10.2-0.2-0.30.3
Intermitt. access day 1 inactive lever presses0.31.22.91.6-1.6-1.1-1.2-1.0-1.1-1.1-1.1-0.9-1.0-1.0-1.2-1.3-1.2-1.2-0.4-0.1-1.70.10.0
Intermitt. access day 15 inactive lever presses0.81.74.91.9-1.2-1.0-1.0-0.9-1.0-0.9-1.0-0.9-1.2-0.9-1.3-1.9-2.2-2.2-0.9-0.8-0.61.2-1.1
Intermitt. access escalation Index0.20.21.41.2-0.2-0.1-0.1-0.2-0.2-0.3-0.3-0.4-0.1-0.2-0.2-0.00.20.2-0.1-0.40.61.1-1.0
Intermittent access day 1 total infusions0.20.30.80.9-0.7-0.8-0.5-0.4-0.4-0.4-0.5-0.4-0.5-0.4-0.5-0.5-0.8-0.8-0.10.1-0.8-0.20.2
Intermittent access day 15 total infusions0.20.31.81.3-0.7-0.6-0.7-0.6-0.5-0.6-0.5-0.5-0.7-0.6-0.4-0.3-0.5-0.5-0.10.1-0.8-0.00.1
Intermittent access terminal intake (last 3 days)0.30.41.21.1-0.8-0.8-0.7-0.7-0.6-0.7-0.6-0.7-0.8-0.7-0.6-0.5-0.8-0.8-0.4-0.3-0.60.3-0.3
Intermittent access total infusions0.10.21.21.1-0.5-0.5-0.4-0.3-0.2-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.6-0.6-0.00.0-0.30.2-0.1
Intermittent access day 1 locomotion0.10.10.60.80.1-0.20.0-0.00.1-0.10.10.00.3-0.00.00.0-0.2-0.20.40.5-0.4-0.50.5
Intermittent access day 15 total locomotion0.00.10.40.3-0.1-0.3-0.3-0.2-0.2-0.3-0.3-0.2-0.1-0.2-0.2-0.1-0.2-0.2-0.00.1-0.6-0.40.4
Intermittent access total locomotion0.10.10.30.50.0-0.4-0.2-0.3-0.2-0.4-0.2-0.30.1-0.3-0.2-0.0-0.3-0.3-0.10.1-0.5-0.20.2
Intermittent access standard deviation1.22.43.90.11.71.61.41.51.61.41.71.61.61.51.71.71.31.31.82.00.5-1.81.9
Left kidney weight0.31.43.9-2.01.70.91.10.80.80.80.80.81.60.81.11.61.71.70.70.60.6-0.80.7
Right kidney weight0.10.52.6-1.60.90.60.70.40.50.40.50.30.90.40.60.91.01.00.2-0.10.80.1-0.1
Cocaine induced anxiety0.50.81.3-0.30.60.90.91.21.01.00.91.10.81.01.01.00.70.70.90.90.9-0.70.7
Post-drug Anxiety0.10.10.50.0-0.70.20.00.30.20.20.10.2-0.40.20.20.1-0.4-0.4-0.0-0.20.60.5-0.5
Baseline Anxiety2.02.33.41.1-1.7-1.2-1.5-1.5-1.3-1.4-1.3-1.5-1.8-1.4-1.5-1.9-1.8-1.8-1.5-1.5-0.71.6-1.6
Tail length0.10.63.0-1.70.50.30.40.60.30.40.20.70.90.70.51.01.01.00.50.5-0.4-0.80.7
Length with tail0.10.51.10.3-0.4-0.9-0.6-0.7-1.0-0.9-1.0-0.8-0.4-0.6-0.8-0.5-0.5-0.5-0.7-0.8-0.31.1-1.0
Length without tail0.61.83.91.7-0.8-1.3-0.9-1.2-1.3-1.3-1.3-1.4-1.2-1.2-1.4-1.6-1.3-1.3-1.2-1.40.12.0-1.9
Times rat made contact with spout2.12.43.1-1.81.41.71.71.61.71.71.71.71.61.61.61.21.21.21.41.50.9-1.71.6
Lifetime Intake0.10.10.70.8-0.4-0.4-0.2-0.1-0.1-0.1-0.1-0.1-0.4-0.1-0.2-0.4-0.6-0.6-0.00.0-0.00.1-0.1
Liver weight, left1.62.73.80.8-1.7-1.9-1.7-1.5-1.9-1.8-1.9-1.6-1.7-1.6-1.8-1.5-1.5-1.5-1.6-1.6-1.41.6-1.6
Liver weight, right0.20.41.2-0.9-0.2-0.6-0.2-0.3-0.6-0.4-0.6-0.4-0.5-0.3-0.6-0.5-0.3-0.3-0.8-1.00.31.1-1.1
Locomotor activity0.60.91.30.4-0.7-1.1-1.0-0.7-1.1-1.1-1.1-0.8-0.9-0.9-1.1-0.8-1.0-1.0-1.0-0.9-0.80.9-0.8
Locomotor testing distance1.62.93.90.8-1.7-2.0-1.8-1.4-2.0-1.8-2.0-1.5-1.7-1.7-1.9-1.8-2.0-2.0-1.7-1.5-1.71.2-1.2
Locomotor testing rearing0.50.91.7-1.0-0.8-1.0-0.7-0.5-1.0-0.9-1.0-0.6-1.0-0.5-1.0-1.0-1.2-1.2-1.2-1.3-0.31.0-1.1
Locomotion in novel chamber1.62.14.30.32.01.21.61.31.31.31.31.11.81.31.52.02.12.11.30.82.0-0.10.1
Locomotion in novel chamber post-restriction0.30.62.1-0.50.70.70.90.70.70.70.60.61.00.70.81.00.90.90.40.11.40.3-0.3
Fecal boli incidents, locomotor time 10.30.42.30.7-0.10.1-0.0-0.20.0-0.00.0-0.00.2-0.10.20.61.51.50.60.7-0.5-0.70.7
Change in fecal boli incidents, locomotor task1.71.72.4-1.31.51.11.21.51.21.31.21.41.51.31.31.61.11.11.21.20.5-1.41.4
Time >=10cm from walls, locomotor time 12.42.53.4-1.11.61.71.71.61.61.61.61.61.91.61.61.61.81.81.71.61.2-1.41.4
Bouts of movement, locomotor time 10.30.41.8-0.10.20.10.0-0.4-0.0-0.3-0.0-0.6-0.4-0.4-0.2-0.5-0.0-0.0-0.5-0.91.11.4-1.4
Total resting periods, locomotor time 10.30.32.1-0.70.60.60.50.10.50.20.5-0.0-0.10.10.3-0.10.40.4-0.1-0.61.50.9-0.9
Rest time, locomotor task time 10.60.73.5-1.60.90.81.00.60.90.70.90.50.20.70.5-0.20.60.6-0.0-0.51.90.7-0.7
Distance moved, locomotor task time 10.30.42.40.9-0.6-0.2-0.5-0.2-0.2-0.2-0.20.00.3-0.2-0.00.60.10.10.51.0-1.5-1.21.3
Vertical activity count, locomotor time 10.10.31.61.3-0.9-0.6-0.5-0.2-0.6-0.3-0.6-0.1-0.1-0.3-0.30.3-0.3-0.30.20.5-1.1-0.50.5
Time >=10cm from walls, locomotor time 20.20.30.9-0.30.60.40.70.70.60.60.60.60.70.70.50.40.50.50.40.20.90.1-0.1
Bouts of movement, locomotor time 20.20.21.21.10.10.10.20.30.10.10.10.1-0.20.2-0.0-0.2-0.5-0.50.1-0.21.11.0-0.9
Total resting periods, locomotor time 20.20.31.20.7-0.10.00.10.1-0.1-0.0-0.1-0.1-0.40.1-0.2-0.5-0.7-0.7-0.2-0.50.91.1-1.0
Rest time, locomotor task time 20.40.53.5-1.90.50.50.4-0.00.30.10.3-0.1-0.10.00.1-0.5-0.5-0.5-0.7-1.01.21.0-1.1
Distance moved, locomotor task time 20.20.31.61.0-0.5-0.6-0.5-0.2-0.5-0.3-0.5-0.10.0-0.2-0.30.20.40.40.20.5-1.3-0.70.7
Vertical activity count, locomotor time 20.10.20.60.8-0.1-0.40.00.4-0.20.2-0.20.40.20.3-0.10.30.40.40.50.7-0.6-0.60.6
Light reinforcement 10.30.84.20.9-0.5-0.8-1.2-1.3-0.9-1.0-0.9-1.1-0.4-1.3-0.7-0.3-0.0-0.0-0.4-0.0-2.0-0.50.4
Light reinforcement 20.30.56.02.4-0.2-0.5-0.7-0.6-0.5-0.5-0.5-0.50.0-0.6-0.20.40.40.40.30.4-0.9-0.10.2
Bone: marrow area1.32.84.3-1.1-1.3-1.7-1.5-1.8-1.7-1.7-1.8-1.8-1.5-1.7-1.7-1.6-1.8-1.8-2.1-2.1-1.01.6-1.7
Bone: maximum diameter0.30.57.9-2.80.1-0.20.10.1-0.2-0.2-0.20.1-0.30.1-0.2-0.1-0.3-0.3-0.7-0.80.10.3-0.4
Bone: maximum force1.42.55.5-2.1-0.7-1.5-1.1-1.6-1.5-1.6-1.6-1.7-1.2-1.6-1.4-1.2-1.2-1.2-2.1-2.3-0.21.9-2.0
Bone: maximum moment1.22.04.8-2.2-0.5-1.3-0.8-1.4-1.3-1.3-1.3-1.5-1.0-1.5-1.3-1.1-1.1-1.1-1.9-2.20.11.8-1.9
Mean time between licks in bursts2.35.77.72.7-2.7-2.7-2.8-2.5-2.7-2.7-2.7-2.5-2.3-2.6-2.5-2.1-2.1-2.1-2.0-1.7-2.51.8-1.7
Mean num. licks in bursts1.11.73.50.70.71.31.11.01.31.31.31.21.31.21.31.31.21.21.71.90.4-1.61.7
Cd content in liver0.40.41.1-0.80.70.70.80.50.70.70.70.50.70.50.70.70.60.60.50.31.1-0.20.2
Co content in liver0.50.60.91.0-0.7-0.9-0.9-0.7-0.9-0.9-0.9-0.7-0.6-0.9-0.8-0.7-0.8-0.8-0.6-0.5-0.90.5-0.4
Cu content in liver0.91.01.40.8-0.7-1.2-1.2-1.0-1.2-1.2-1.2-1.0-1.1-1.0-1.1-1.0-1.1-1.1-1.0-0.9-1.10.7-0.7
Fe content in liver0.60.71.8-0.90.90.70.50.80.70.70.70.90.90.80.81.00.80.80.70.9-0.6-1.31.3
K content in liver1.91.83.50.6-1.1-1.4-1.0-1.2-1.4-1.4-1.4-1.4-1.4-1.4-1.3-1.3-1.3-1.3-1.4-1.60.01.9-1.9
Mg content in liver2.12.12.81.7-1.3-1.6-1.6-1.4-1.6-1.6-1.6-1.4-1.5-1.5-1.6-1.4-1.6-1.6-1.3-1.2-1.21.3-1.2
Mn content in liver0.10.11.1-0.0-0.1-0.3-0.4-0.1-0.3-0.3-0.3-0.1-0.0-0.3-0.20.10.10.1-0.20.1-1.1-0.40.4
Na content in liver0.50.51.1-0.9-0.3-0.8-0.6-0.4-0.8-0.8-0.8-0.5-0.8-0.6-0.8-0.6-0.4-0.4-1.0-1.0-0.40.8-0.8
Rb content in liver0.30.43.60.6-0.1-0.3-0.7-0.6-0.3-0.3-0.3-0.4-0.2-0.4-0.3-0.10.10.1-0.00.4-1.9-1.01.0
Se content in liver0.70.82.0-0.30.30.70.51.00.70.70.71.01.00.80.80.90.80.81.01.2-0.5-1.41.4
Sr content in liver1.61.42.9-0.30.61.21.31.71.21.21.21.61.21.41.21.11.11.11.31.11.5-0.70.7
Zn content in liver0.10.20.40.60.10.50.30.40.50.50.50.40.40.40.40.2-0.0-0.00.60.60.3-0.40.5
Bone: minimum diameter3.46.39.5-1.4-2.1-2.7-2.3-2.6-2.7-2.7-2.8-2.6-2.4-2.6-2.6-2.3-2.4-2.4-3.1-3.1-1.72.4-2.5
Time in familiar zone, hab. session 11.91.82.5-1.41.21.41.41.61.41.41.41.61.31.61.41.51.41.41.21.11.0-1.21.1
Time in novel zone, hab. session 10.70.71.10.1-0.5-0.9-0.9-1.0-0.9-0.9-0.9-1.0-0.9-1.0-0.9-0.8-0.7-0.7-1.0-1.0-0.70.7-0.8
Total zone transitions, hab. session 11.72.43.11.4-1.7-1.6-1.7-1.7-1.6-1.6-1.6-1.7-1.7-1.7-1.6-1.6-1.5-1.5-1.4-1.3-1.31.2-1.2
Total locomotion distance, hab. session 10.71.03.51.9-1.2-1.0-1.0-0.9-1.0-1.0-1.0-1.0-1.1-1.0-1.0-1.1-1.0-1.0-0.6-0.6-0.60.9-0.8
Locomotion velocity, hab. session 11.01.46.32.5-1.4-1.0-1.1-1.0-1.0-1.1-1.0-1.1-1.2-1.2-1.1-1.3-1.2-1.2-0.6-0.5-0.61.0-0.9
Time in familiar zone, hab. session 26.87.19.7-3.12.72.93.12.82.92.92.92.72.82.82.92.82.62.62.21.83.1-1.61.6
Time in novel zone, hab. session 24.95.06.71.7-2.0-2.5-2.6-2.3-2.5-2.5-2.5-2.3-2.4-2.4-2.5-2.4-2.1-2.1-2.1-1.8-2.51.5-1.5
Total zone transitions, hab. session 21.11.52.11.4-1.2-1.1-1.1-1.2-1.1-1.1-1.1-1.3-1.2-1.3-1.2-1.5-1.3-1.3-1.0-1.1-0.31.4-1.3
Total locomotion distance, hab. session 20.91.13.92.0-1.2-0.9-1.1-0.9-0.9-0.9-0.9-1.0-1.1-1.1-1.1-1.4-1.3-1.3-0.6-0.4-0.90.6-0.5
Locomotion velocity, hab. session 21.01.35.32.3-1.3-1.0-1.1-1.0-1.0-1.0-1.0-1.1-1.1-1.2-1.1-1.4-1.4-1.4-0.6-0.5-0.80.8-0.7
Novel to familiar place preference ratio1.61.72.70.9-1.0-1.3-1.1-1.3-1.3-1.3-1.3-1.4-1.4-1.4-1.4-1.5-1.5-1.5-1.3-1.4-0.21.6-1.6
Novelty place preference1.41.52.90.7-0.9-1.1-0.9-1.1-1.1-1.2-1.1-1.3-1.2-1.2-1.2-1.4-1.4-1.4-1.2-1.40.11.7-1.7
Time in novel zone, NPP test1.41.53.20.4-0.8-1.1-0.8-1.1-1.1-1.2-1.1-1.3-1.2-1.2-1.2-1.3-1.3-1.3-1.3-1.50.21.8-1.8
Total zone transitions, NPP test1.21.84.32.1-1.4-1.1-1.2-1.4-1.1-1.2-1.1-1.4-1.3-1.3-1.3-1.6-1.6-1.6-0.9-1.0-0.31.4-1.3
Total locomotion distance, NPP test0.70.94.52.1-0.9-0.7-0.7-0.8-0.7-0.7-0.7-0.9-1.0-0.9-0.9-1.2-1.1-1.1-0.4-0.60.21.2-1.1
Locomotion velocity, NPP test0.71.06.02.5-0.9-0.6-0.6-0.8-0.6-0.7-0.6-0.9-0.9-0.8-0.8-1.1-1.1-1.1-0.3-0.40.21.1-1.0
Intraocular pressure0.30.50.80.40.40.80.50.60.90.60.80.60.60.60.80.70.80.80.90.80.6-0.50.5
Delta distance traveled before/after self-admin3.03.24.6-1.52.11.92.11.91.81.61.91.91.81.81.92.01.81.81.81.61.4-1.51.4
Delta ambulatory time before/after self-admin2.93.66.0-1.62.42.02.32.12.01.82.02.01.92.02.02.01.91.91.81.51.7-1.31.3
Parametrial fat weight0.00.10.2-0.2-0.2-0.3-0.3-0.3-0.3-0.3-0.3-0.4-0.3-0.4-0.3-0.5-0.2-0.2-0.3-0.40.00.4-0.4
Pavlov. Cond. lever latency0.50.61.6-0.51.00.60.60.80.60.60.60.80.90.80.81.11.21.20.70.70.1-0.80.8
Pavlov. Cond. magazine entry latency0.10.10.5-0.70.30.40.30.40.40.40.40.30.10.30.30.30.20.20.20.20.2-0.40.3
Pavlov. Cond. change in total contacts0.30.31.41.2-0.50.40.20.30.40.50.40.30.20.30.30.10.00.00.81.0-0.3-0.80.9
Pavlov. Cond. index score0.00.00.1-0.3-0.10.30.20.20.30.30.30.2-0.10.20.2-0.1-0.2-0.20.10.10.4-0.10.1
Pavlov. Cond. latency score0.00.00.1-0.2-0.10.30.20.20.30.30.30.2-0.10.20.2-0.1-0.3-0.30.20.20.3-0.20.2
Pavlov. Cond. lever contacts0.60.71.61.0-1.0-0.6-0.6-0.8-0.6-0.6-0.6-0.9-0.9-0.8-0.8-1.1-1.2-1.2-0.6-0.6-0.10.9-0.8
Pavlov. Cond. magazine entry number0.10.11.11.0-0.1-0.1-0.20.0-0.1-0.1-0.10.10.20.0-0.0-0.00.10.10.20.3-0.4-0.20.3
Pavlov. Cond. intertrial magazine entries1.01.18.93.0-1.0-0.9-1.1-0.8-0.9-0.9-0.9-0.8-0.9-0.9-1.0-1.1-1.0-1.0-0.3-0.1-1.10.5-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.2-0.00.40.30.30.40.40.40.3-0.10.30.30.0-0.2-0.20.30.30.3-0.30.3
Pavlov. Cond. response bias0.20.30.70.1-0.6-0.4-0.3-0.5-0.4-0.4-0.4-0.6-0.7-0.5-0.4-0.6-0.7-0.7-0.5-0.70.40.8-0.8
Pavlov. Cond. lever latency1.62.23.0-1.31.71.61.71.61.61.71.61.51.41.51.61.41.51.51.41.21.5-1.11.0
Pavlov. Cond. magazine entry latency0.30.42.5-1.6-0.2-0.30.0-0.0-0.3-0.3-0.3-0.2-0.4-0.3-0.3-0.3-0.4-0.4-0.8-1.00.61.0-1.0
Pavlov. Cond. change in total contacts1.11.82.50.8-1.4-1.6-1.5-1.2-1.6-1.6-1.6-1.3-1.3-1.4-1.5-1.2-1.4-1.4-1.4-1.3-1.41.1-1.1
Pavlov. Cond. index score1.31.82.40.1-1.4-1.4-1.3-1.2-1.4-1.5-1.4-1.3-1.3-1.4-1.4-1.3-1.4-1.4-1.5-1.5-0.81.4-1.4
Pavlov. Cond. latency score1.31.82.40.0-1.3-1.4-1.3-1.2-1.4-1.5-1.4-1.3-1.3-1.3-1.4-1.3-1.4-1.4-1.5-1.6-0.81.4-1.4
Pavlov. Cond. lever contacts1.21.62.31.1-1.5-1.4-1.4-1.2-1.4-1.4-1.4-1.2-1.2-1.3-1.3-1.2-1.4-1.4-1.2-1.0-1.30.9-0.9
Pavlov. Cond. magazine entry number0.20.21.11.10.20.30.10.10.30.30.30.20.30.30.30.20.30.30.60.7-0.2-0.60.7
Pavlov. Cond. intertrial magazine entries0.10.10.60.8-0.00.20.00.20.20.10.20.30.20.40.10.1-0.0-0.00.40.5-0.1-0.30.4
Pavlov. Cond. lever-magazine prob. diff.0.91.21.60.1-1.2-1.2-1.1-1.0-1.2-1.2-1.2-1.1-1.1-1.1-1.2-1.1-1.2-1.2-1.3-1.2-0.71.1-1.1
Pavlov. Cond. response bias1.21.62.10.4-1.4-1.4-1.3-1.3-1.4-1.5-1.4-1.3-1.2-1.3-1.3-1.2-1.3-1.3-1.4-1.3-1.01.2-1.2
Time in closed arm before self-admin0.10.20.9-0.50.90.20.50.30.20.10.20.10.20.20.30.40.10.1-0.3-0.50.70.6-0.6
Time in closed arm after self-admin0.10.10.50.70.40.10.30.40.10.20.20.2-0.00.30.10.0-0.2-0.20.0-0.10.70.4-0.4
Time in open arm before self-admin0.80.92.80.0-1.7-1.0-1.0-0.8-1.0-0.7-1.0-0.6-1.5-0.6-1.1-1.4-1.0-1.0-0.5-0.2-1.4-0.30.3
Time in open arm after self-admin0.10.10.8-0.9-0.10.1-0.1-0.20.0-0.10.0-0.20.1-0.2-0.0-0.20.20.2-0.3-0.40.20.3-0.3
Bone: periosteal estimation1.73.56.2-2.0-1.4-1.9-1.5-1.9-1.9-1.9-1.9-2.0-1.7-2.0-1.9-1.8-1.9-1.9-2.4-2.5-1.01.9-2.0
Bone: periosteal perimeter0.91.65.8-2.4-0.6-1.1-0.7-1.1-1.1-1.1-1.1-1.2-1.1-1.1-1.1-0.9-1.0-1.0-1.7-1.9-0.01.4-1.6
Bone: post-yield work1.82.63.91.1-1.6-1.7-1.7-2.0-1.7-1.7-1.7-1.9-1.6-1.9-1.7-1.7-1.6-1.6-1.6-1.4-1.51.3-1.3
Progressive ratio test 1 active lever presses0.00.00.20.30.0-0.5-0.1-0.2-0.2-0.3-0.3-0.30.0-0.2-0.2-0.2-0.1-0.1-0.0-0.1-0.10.1-0.1
Progressive ratio test 1 breakpoint0.00.00.10.30.1-0.4-0.0-0.1-0.1-0.2-0.2-0.10.1-0.1-0.1-0.1-0.0-0.00.10.0-0.00.1-0.0
Progressive ratio test 1 inactive lever presses0.71.01.91.4-1.4-1.2-1.1-1.0-1.0-1.0-1.1-0.9-1.0-1.0-1.1-1.2-0.9-0.9-0.4-0.2-1.30.2-0.1
Progressive ratio test 2 active lever presses0.70.93.10.5-0.9-1.3-1.3-1.1-1.1-1.3-1.1-1.0-0.8-1.1-0.8-0.3-0.0-0.0-0.6-0.2-1.8-0.40.3
Progressive ratio test 2 breakpoint0.80.93.30.5-0.9-1.3-1.3-1.1-1.1-1.2-1.1-1.0-0.8-1.1-0.8-0.2-0.0-0.0-0.6-0.2-1.8-0.40.4
Progressive ratio test 2 inactive lever presses0.00.10.10.20.2-0.3-0.1-0.20.0-0.1-0.1-0.20.3-0.20.10.30.30.30.20.2-0.2-0.30.3
Incentive Sensitization - Responses1.52.15.60.6-1.7-1.8-2.0-1.8-1.8-1.9-1.7-1.6-1.6-1.8-1.5-0.6-0.4-0.4-1.2-0.8-2.40.0-0.1
Incentive Sensitization - Breakpoint1.52.05.20.6-1.7-1.8-2.0-1.7-1.8-1.9-1.7-1.6-1.5-1.7-1.4-0.6-0.4-0.4-1.2-0.8-2.30.1-0.1
Sum of active levers in priming session hrs 5-60.30.31.91.4-0.6-0.1-0.5-0.2-0.2-0.3-0.1-0.20.1-0.4-0.2-0.1-0.3-0.30.30.7-1.1-0.70.7
Progressive ratio0.10.20.8-0.4-0.6-0.0-0.30.00.10.20.00.2-0.60.10.0-0.0-0.1-0.10.00.4-0.9-0.90.8
Food seeking constrained by brief footshock0.20.31.10.10.80.30.40.30.40.20.30.20.30.20.50.81.01.00.2-0.00.80.3-0.3
Seeking ratio, punishment vs. effort0.10.20.60.70.5-0.00.2-0.0-0.0-0.3-0.1-0.20.5-0.20.00.10.20.20.1-0.20.80.7-0.7
Retroperitoneal fat weight0.31.47.7-0.6-0.9-1.4-1.5-1.1-1.4-1.2-1.3-0.9-0.7-1.2-1.2-0.9-0.4-0.4-0.9-0.3-2.8-0.90.8
Reaction time number correct2.03.88.2-2.92.12.22.12.32.12.02.12.02.02.02.01.91.91.91.41.12.0-1.11.0
Reaction time mean minus median1.43.46.41.3-2.5-2.0-2.3-1.8-1.9-2.0-1.9-1.7-2.0-1.7-2.0-2.1-1.9-1.9-1.6-1.3-2.11.0-1.0
Reaction time mean minus median AUC2.66.613.92.0-3.7-2.5-3.1-2.4-2.5-2.7-2.5-2.4-3.0-2.5-2.7-3.0-2.7-2.7-2.2-1.8-2.81.4-1.4
Reaction time num false alarms0.40.53.7-1.90.2-0.5-0.4-0.6-0.6-0.8-0.6-0.7-0.1-0.7-0.40.20.10.1-1.0-1.0-0.60.4-0.5
Reaction time num false alarms AUC0.30.54.2-2.00.1-0.5-0.4-0.5-0.6-0.7-0.6-0.6-0.2-0.6-0.40.10.00.0-1.0-1.1-0.40.5-0.6
Reaction time trials correct on left2.03.88.2-2.92.12.22.12.32.12.02.12.02.02.02.01.91.91.91.41.12.0-1.11.0
Reaction time trials on left1.93.57.8-2.82.02.12.02.32.01.92.02.01.91.91.91.81.81.81.31.01.9-1.11.0
Reaction time mean1.82.94.91.6-1.9-1.7-1.8-1.8-1.7-1.7-1.7-1.6-2.2-1.5-1.8-2.2-2.0-2.0-1.4-1.2-1.61.1-1.1
Reaction time mean AUC3.04.77.42.0-2.5-2.2-2.3-2.2-2.2-2.2-2.2-2.1-2.7-2.0-2.4-2.7-2.5-2.5-1.8-1.6-1.91.5-1.5
Median of all reaction times1.42.03.51.4-1.5-1.4-1.4-1.5-1.3-1.3-1.3-1.3-1.9-1.2-1.5-1.8-1.7-1.7-1.2-1.0-1.21.0-1.0
Reaction time omissions3.65.38.92.2-3.0-2.4-2.7-2.1-2.4-2.3-2.4-2.1-3.0-2.2-2.4-2.5-2.4-2.4-1.9-1.4-2.81.0-1.0
Reaction time false alarm rate1.11.52.4-0.5-0.8-1.5-1.4-1.6-1.5-1.6-1.5-1.5-1.0-1.5-1.2-0.7-0.7-0.7-1.5-1.4-1.40.8-0.9
Reaction time premature initiation rate0.30.41.8-1.30.50.70.80.40.70.70.70.50.40.60.60.20.20.20.1-0.11.20.1-0.1
Reaction time premature initiations1.22.17.2-2.71.41.61.71.61.61.51.61.51.31.51.51.11.01.00.70.42.1-0.50.4
Std. dev. reaction times3.05.69.11.4-2.7-2.4-2.5-2.2-2.3-2.3-2.3-2.2-3.0-2.1-2.5-2.9-2.9-2.9-2.3-2.1-1.71.9-1.9
Reaction time trials completed1.93.57.8-2.82.02.12.02.32.01.92.02.01.91.91.91.81.81.81.31.01.9-1.11.0
Reaction time trials AUC1.73.37.3-2.72.02.02.02.21.91.81.92.01.81.91.91.71.71.71.31.01.8-1.11.0
Run reversals in cocaine runway, females0.20.22.51.6-0.1-0.1-0.2-0.2-0.3-0.3-0.3-0.2-0.0-0.2-0.10.30.50.50.20.2-0.10.3-0.2
Run reversals in cocaine runway, males0.20.20.60.40.70.20.40.10.30.20.30.20.80.10.40.70.70.70.50.50.2-0.30.3
Latency to leave start box in cocaine runway0.30.41.90.50.30.30.10.30.30.40.30.50.20.40.2-0.1-0.1-0.10.71.1-0.8-1.41.4
Latency to leave start box in cocaine runway, F0.40.52.1-0.40.80.60.40.40.60.50.60.50.70.50.50.20.50.50.81.0-0.5-1.41.4
Latency to leave start box in cocaine runway, M0.30.31.81.3-0.5-0.5-0.5-0.3-0.5-0.2-0.4-0.2-0.6-0.3-0.5-0.5-0.6-0.6-0.10.2-0.9-0.30.3
Std. dev. time between licks in bursts5.47.310.01.8-2.4-3.0-3.2-3.0-3.0-3.1-3.0-2.9-2.7-3.0-2.9-2.5-2.7-2.7-2.7-2.3-3.11.8-1.8
Total sessions with >9 infusions0.50.61.31.0-0.9-1.0-0.7-0.7-0.6-0.7-0.7-0.6-0.8-0.7-0.8-1.1-1.0-1.0-0.3-0.2-0.80.1-0.1
Short access day 1 total inactive lever presses0.10.10.30.6-0.1-0.5-0.2-0.5-0.3-0.4-0.4-0.5-0.2-0.5-0.3-0.3-0.1-0.1-0.0-0.1-0.30.1-0.1
Short access day 10 total inactive lever presses0.41.02.50.5-1.2-1.1-1.2-1.2-1.2-1.1-1.2-1.1-0.9-1.2-1.1-1.0-0.7-0.7-0.7-0.4-1.60.0-0.0
Short access day 1 total infusions0.10.20.80.9-0.0-0.10.30.30.30.30.20.30.20.30.1-0.2-0.4-0.40.60.70.0-0.50.5
Short access day 10 total infusions0.20.30.80.6-0.3-0.6-0.3-0.3-0.3-0.3-0.4-0.3-0.6-0.3-0.5-0.9-0.9-0.9-0.5-0.60.20.8-0.8
Short access total infusions0.30.41.30.7-0.7-0.8-0.5-0.5-0.4-0.4-0.5-0.5-0.7-0.5-0.6-1.0-1.1-1.1-0.5-0.4-0.20.5-0.5
Short access day 1 locomotion0.10.10.5-0.20.4-0.00.30.10.20.10.10.10.20.1-0.1-0.7-0.6-0.60.00.10.0-0.20.2
Short access day 10 total locomotion1.12.03.3-0.71.51.31.51.41.41.21.41.41.81.41.41.51.41.41.61.60.7-1.51.5
Short access total locomotion0.10.10.3-0.30.4-0.00.40.30.30.30.20.30.50.30.30.10.10.10.30.30.3-0.30.3
One hour access (0.3 mA shock)0.10.10.50.1-0.1-0.1-0.2-0.2-0.0-0.20.0-0.10.2-0.20.20.70.60.60.20.4-0.5-0.60.6
Compulsive drug intake0.81.02.0-0.9-0.8-1.0-1.1-1.2-1.2-1.1-1.1-1.2-0.8-1.2-0.80.1-0.1-0.1-1.4-1.4-0.81.0-1.1
One hour access (shock baseline)0.20.31.10.60.00.40.30.40.60.40.50.50.30.40.40.00.20.20.91.0-0.1-1.01.0
Social response proportion0.20.31.10.50.2-0.3-0.1-0.5-0.3-0.4-0.3-0.6-0.2-0.5-0.3-0.4-0.2-0.2-0.5-0.70.71.0-1.0
Social responses0.20.21.8-1.30.1-0.10.1-0.2-0.2-0.2-0.2-0.4-0.1-0.3-0.2-0.40.10.1-0.6-0.80.50.6-0.7
Social time0.10.10.9-0.10.20.10.1-0.10.00.20.0-0.10.4-0.10.20.60.90.90.20.10.1-0.10.1
Soleus weight0.31.02.9-1.51.31.01.30.81.01.00.90.81.01.00.90.90.90.90.60.21.7-0.0-0.0
Bone: stiffness0.30.51.2-0.8-0.3-0.7-0.4-0.6-0.7-0.8-0.7-0.7-0.5-0.5-0.6-0.4-0.4-0.4-0.9-1.10.11.1-1.1
Tibialis anterior weight0.30.91.2-0.71.11.11.00.81.11.01.10.81.00.91.01.01.01.00.90.80.8-0.80.8
Time to tail flick, vehicle, before self-admin0.10.11.1-1.0-0.20.0-0.1-0.40.1-0.10.1-0.20.2-0.3-0.0-0.3-0.5-0.5-0.20.0-0.5-0.50.5
Time to tail flick, vehicle, after self-admin1.11.43.41.4-1.4-1.3-1.5-1.6-1.3-1.4-1.3-1.5-0.6-1.6-1.2-1.0-0.8-0.8-0.7-0.3-1.90.1-0.1
Time to tail flick, test, before self-admin0.80.82.41.0-1.1-1.2-1.1-1.0-1.1-1.3-1.1-1.0-0.3-1.2-1.0-0.6-0.6-0.6-0.5-0.2-1.6-0.10.1
Time to tail flick, test, after self-admin0.40.51.90.21.10.50.60.50.50.40.50.41.40.40.61.01.01.00.60.60.3-0.40.4
Delta time to tail flick, vehicle, before/after SA0.20.21.81.4-0.1-0.5-0.3-0.4-0.5-0.4-0.5-0.40.0-0.4-0.30.00.40.40.20.1-0.40.2-0.2
Delta time to tail flick, test, before/after SA1.21.22.0-0.81.41.11.11.11.11.21.01.01.41.11.11.21.21.21.11.00.7-0.90.9
Tibia length0.00.10.60.8-0.1-0.2-0.1-0.2-0.2-0.3-0.2-0.3-0.1-0.3-0.2-0.1-0.3-0.3-0.1-0.30.60.7-0.7
Ambulatory time before self-admin0.10.10.80.9-0.4-0.2-0.20.2-0.2-0.0-0.20.1-0.10.0-0.2-0.30.10.10.20.4-0.4-0.30.4
Ambulatory time after self-admin3.13.76.4-0.92.12.02.22.52.02.02.02.32.02.11.91.81.61.62.01.91.5-1.61.6
Bone: tissue strength0.00.00.40.6-0.00.00.10.00.0-0.00.1-0.00.2-0.10.0-0.1-0.0-0.00.10.10.50.2-0.2
Total heroin consumption0.10.20.8-0.20.1-0.3-0.20.1-0.2-0.2-0.2-0.30.2-0.4-0.10.1-0.3-0.3-0.6-0.80.30.9-0.9
Bone: trabecular number1.82.927.6-5.32.41.31.81.31.31.41.31.31.31.31.31.11.01.00.2-0.21.5-0.60.4
Bone: trabecular spacing1.11.513.83.7-1.7-1.0-1.1-0.8-1.0-1.0-1.0-0.8-1.0-0.7-1.0-0.9-0.9-0.9-0.2-0.2-0.41.1-0.9
Bone: trabecular thickness5.56.821.3-4.63.62.63.02.62.62.62.62.52.62.62.62.52.32.31.71.32.5-1.71.5
Bone: trabecular tissue density0.30.51.71.30.50.60.40.70.60.50.70.70.70.60.60.50.50.50.91.00.3-0.70.7
Water consumed over 24 hours0.40.53.5-1.90.70.70.70.50.70.70.70.60.60.60.60.40.50.50.20.20.5-0.60.5
Number of responses in last shaping day0.60.71.4-0.40.50.60.70.80.90.90.80.80.80.80.80.80.70.71.01.10.1-1.21.2