Hub : Genes

Gfap

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Gfap 0.08 0.04 4.8e-08 0.03 0.06 0.06 0.04 2.2e-04 6.1e-07 9.6e-07 6.6e-05
2 IL mRNA stability Gfap 0.34 0.13 3.5e-04 0.06 0.13 0.17 0.14 1.6e-02 5.9e-04 7.2e-05 3.5e-04
3 IC gene expression Gfap 0.2 0.09 2.5e-06 0.07 0.15 0.14 0.13 6.7e-04 1.1e-06 2.4e-06 3.2e-06
4 NAcc mRNA stability Gfap 0.28 0.08 0.0e+00 0.27 0.28 0.28 0.28 5.6e-41 1.0e-41 5.7e-43 1.1e-42
5 PL gene expression Gfap 0.18 0.07 1.7e-16 0.14 0.16 0.17 0.14 1.6e-15 5.3e-17 5.7e-18 2.7e-15
6 Brain gene expression Gfap 0.21 0.11 5.3e-14 0.12 0.13 0.15 0.13 1.5e-11 4.2e-12 7.8e-14 4.3e-12
7 OFC gene expression Gfap 0.23 0.11 4.6e-04 0.11 0.08 0.15 0.12 1.2e-03 7.2e-03 2.5e-04 1.1e-03
8 PL mRNA stability Gfap 0.26 0.08 0.0e+00 0.24 0.24 0.26 0.26 1.9e-25 4.3e-26 2.4e-28 1.0e-28
9 BLA mRNA stability Gfap 0.34 0.1 0.0e+00 0.28 0.3 0.29 0.28 2.8e-15 2.5e-16 1.2e-15 3.3e-15
10 BLA gene expression Gfap 0.18 0.07 1.7e-08 0.12 0.13 0.12 0.12 9.4e-07 3.3e-07 9.5e-07 5.6e-07
11 IC mRNA stability Gfap 0.32 0.11 1.6e-12 0.13 0.26 0.25 0.27 3.4e-06 2.6e-11 5.8e-11 1.3e-11
12 NAcc gene expression Gfap 0.07 0.03 1.8e-10 0.07 0.06 0.07 0.06 2.4e-11 2.3e-09 3.0e-10 1.3e-09
13 RMTg mRNA stability Gfap 0.21 0.09 1.4e-04 0.14 0.05 0.07 0.08 1.2e-04 1.5e-02 5.3e-03 3.2e-03
14 IL gene expression Gfap 0.2 0.12 2.3e-03 0.08 0.06 0.04 0.08 5.2e-03 1.4e-02 3.3e-02 6.4e-03
15 LHb mRNA stability Gfap 0.61 0.12 2.2e-11 0.24 0.41 0.3 0.39 2.3e-06 8.5e-11 6.5e-08 3.5e-10
16 Brain mRNA stability Gfap 0.51 0.09 0.0e+00 0.34 0.57 0.56 0.56 1.5e-32 6.5e-64 6.3e-62 2.1e-63
17 OFC mRNA stability Gfap 0.47 0.14 4.5e-06 0.07 0.17 0.15 0.14 9.9e-03 7.2e-05 2.0e-04 4.3e-04
18 pVTA mRNA stability Gfap 0.5 0.09 0.0e+00 0.5 0.6 0.6 0.6 6.4e-46 5.7e-60 2.3e-59 2.9e-59
19 Adipose gene expression Gfap 0.03 0.02 4.6e-03 0 0 -0 -0 2.9e-01 7.7e-02 5.9e-01 4.2e-01
20 pVTA gene expression Gfap 0.07 0.05 2.6e-03 0.01 0.01 0.03 0.03 2.3e-02 2.2e-02 2.2e-03 2.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.32.35.1-1.00.92.20.4-2.3-2.0-2.0-0.8-0.21.9-0.9-2.02.0-1.8-0.7-1.1-1.5-1.01.6-1.5
Area under the delay curve0.10.10.5-0.3-0.6-0.2-0.30.50.30.20.30.1-0.20.30.3-0.30.30.30.30.70.3-0.30.7
BMI with tail2.07.113.50.2-2.6-1.8-2.52.21.22.23.33.2-3.33.72.9-2.92.53.13.12.13.1-3.01.5
BMI without tail1.05.311.6-1.2-2.8-0.3-2.90.71.20.73.23.4-2.23.42.0-2.01.43.23.02.13.0-2.40.8
Body weight2.310.023.7-2.3-4.1-0.2-4.40.71.10.64.94.8-2.54.62.2-2.21.74.54.22.54.1-3.00.7
Weight adjusted by age0.10.31.4-1.0-1.2-0.2-0.90.3-0.1-0.10.60.20.10.30.2-0.20.10.30.51.00.6-0.21.1
Bone surface1.93.711.4-2.7-0.83.3-0.9-2.7-3.4-3.10.40.82.1-0.2-2.42.4-2.5-0.1-0.5-0.4-0.11.3-1.0
Bone volume1.42.811.0-1.9-0.22.8-0.4-2.3-3.3-2.6-0.00.41.9-0.5-2.12.1-2.1-0.4-0.8-0.8-0.41.4-1.1
Breakpoint value in progressive ratio session0.20.31.2-1.1-0.50.8-0.2-0.4-0.1-0.9-0.5-0.30.8-0.5-0.70.7-0.8-0.2-0.30.7-0.20.10.1
Number of licking bursts0.51.73.4-0.6-1.2-0.9-1.60.51.21.01.41.5-1.11.61.1-1.11.31.71.71.21.6-1.8-0.7
Context. condit. distance diff. score1.92.37.01.0-0.7-2.0-0.32.41.92.10.80.2-1.51.01.9-1.92.20.81.10.60.6-0.92.6
Locomotion velocity, session 10.30.40.90.30.70.40.6-0.2-0.6-0.5-0.6-0.70.6-0.4-0.70.7-0.4-0.9-0.8-0.9-0.71.00.3
Locomotion distance, session 10.20.31.00.61.00.20.7-0.2-0.2-0.0-0.4-0.40.1-0.4-0.30.30.1-0.7-0.7-0.7-0.50.7-0.6
Locomotion velocity, session 21.82.24.40.91.80.52.0-0.20.2-0.6-1.8-2.01.3-1.7-1.11.1-1.1-2.1-1.8-1.7-1.92.00.7
Locomotion distance, session 20.60.92.60.71.60.51.2-0.8-0.3-0.5-0.9-0.90.7-0.9-0.70.7-0.6-1.2-1.2-1.1-1.01.2-1.1
Locomotion velocity, session 30.10.10.60.30.3-0.00.00.1-0.70.0-0.1-0.00.00.1-0.20.20.0-0.2-0.2-0.7-0.20.40.5
Locomotion distance, session 30.20.20.5-0.2-0.2-0.4-0.50.30.10.50.50.4-0.40.60.3-0.30.70.60.60.40.5-0.4-0.1
Stereotopy head waving bouts, day 30.70.82.11.40.9-0.21.10.4-0.80.0-1.3-1.10.1-0.7-0.10.1-0.4-1.3-1.2-1.2-1.11.00.8
Stereotopy head waving duration, day 30.40.51.51.20.7-0.40.90.5-0.50.3-1.0-1.0-0.1-0.70.1-0.1-0.2-1.0-0.9-0.7-0.80.70.8
Locomotion velocity, session 70.60.73.21.40.2-1.10.61.30.71.0-0.5-0.5-0.6-0.00.7-0.70.8-0.2-0.1-0.9-0.50.11.8
Locomotion distance, session 70.30.41.90.90.3-0.80.61.00.60.8-0.2-0.6-0.3-0.20.6-0.60.6-0.3-0.1-0.4-0.40.31.4
Stereotopy head waving bouts, day 70.91.12.20.20.80.71.1-0.5-0.6-1.1-1.4-1.01.1-1.1-1.31.3-1.5-1.2-1.2-1.3-1.10.80.3
Stereotopy head waving duration, day 71.21.43.30.81.30.21.6-0.2-0.7-0.7-1.8-1.40.9-1.5-1.21.2-1.3-1.5-1.5-1.5-1.40.80.3
Locomotion velocity, session 80.70.82.21.0-0.3-0.8-0.41.10.81.01.01.0-1.51.21.1-1.11.20.50.7-0.10.8-0.60.8
Locomotion distance, session 80.50.71.91.40.8-1.00.91.21.01.1-0.3-0.8-0.4-0.40.7-0.71.0-0.6-0.4-0.5-0.50.51.2
Degree of sensitization distance0.20.32.10.2-0.6-0.3-0.20.70.60.30.50.1-0.30.40.7-0.70.30.20.40.10.20.11.4
Degree of sensitization stereotypy0.70.71.50.10.80.31.0-0.3-0.2-0.8-1.2-0.91.0-1.0-1.11.1-1.2-1.0-0.9-1.1-0.90.50.2
Conditioned locomotion0.00.00.60.0-0.0-0.0-0.10.10.80.2-0.2-0.00.10.00.1-0.10.10.10.1-0.1-0.10.10.1
Cocaine response after cond. corrected0.10.10.9-0.10.10.1-0.10.00.8-0.10.40.30.10.3-0.10.1-0.30.30.3-0.7-0.00.20.9
Cocaine response after cond. not corrected0.40.62.4-0.20.80.70.5-0.70.6-0.8-0.3-0.21.0-0.3-1.01.0-1.0-0.3-0.3-1.6-0.71.00.4
Cocaine response before conditioning1.01.21.90.01.21.01.0-1.1-0.4-1.1-1.1-0.81.2-1.1-1.41.4-1.1-1.2-1.2-1.3-1.01.1-1.2
Saline control response0.30.41.0-0.7-0.50.6-0.8-0.60.3-0.30.61.0-0.30.80.1-0.1-0.10.80.50.80.7-0.6-0.9
Bone: connectivity density2.13.37.4-1.70.52.70.3-2.5-2.4-2.6-0.7-0.42.4-1.2-2.52.5-2.3-1.0-1.3-1.2-1.11.8-1.2
Bone: cortical apparent density3.45.415.53.13.9-0.73.7-0.40.70.6-3.4-3.20.7-2.8-0.70.7-0.5-2.8-2.8-2.5-2.91.8-1.8
Bone: cortical area1.32.18.6-1.00.22.30.1-2.0-2.9-2.10.00.21.4-0.5-1.91.9-1.9-0.4-0.9-0.9-0.61.2-1.3
Bone: cortical porosity3.94.314.5-3.8-1.83.4-2.1-2.6-3.0-3.11.71.81.90.6-2.12.1-2.21.00.60.71.00.7-0.3
Bone: cortical porosity2.73.08.9-3.0-2.02.4-2.3-1.6-2.4-2.12.22.30.81.3-1.11.1-1.21.51.20.81.40.10.3
Bone: cortical thickness1.83.08.21.42.80.62.2-1.4-1.0-0.7-1.9-1.61.2-1.7-1.41.4-1.3-1.6-1.9-2.9-2.21.8-1.7
Bone: cortical thickness3.64.46.80.32.41.22.0-2.0-1.8-1.5-2.5-2.32.5-2.5-2.02.0-2.2-2.1-2.4-2.5-2.62.5-1.4
Bone: cortical tissue density3.45.415.23.03.9-0.63.6-0.40.70.6-3.4-3.20.8-2.8-0.70.7-0.5-2.8-2.9-2.4-2.91.8-1.8
Condit. Reinf. active minus inactive responses0.50.62.8-1.7-0.61.0-0.6-1.0-0.7-1.00.30.20.9-0.1-0.60.6-0.70.30.21.00.30.0-0.8
Condit. Reinf. active-inactive response ratio0.10.21.1-1.1-0.20.3-0.2-0.20.0-0.30.1-0.30.7-0.3-0.30.3-0.2-0.00.00.90.10.2-0.1
Condit. Reinf. active responses0.40.61.7-1.3-0.11.3-0.2-1.2-0.6-1.1-0.00.01.0-0.3-0.90.9-1.0-0.0-0.20.5-0.10.5-0.8
Condit. Reinf. inactive responses0.40.61.40.20.61.20.5-1.0-0.9-0.9-0.6-0.20.6-0.5-0.80.8-0.9-0.6-0.8-1.0-0.71.0-0.6
Incentive salience index mean0.60.82.5-1.6-0.31.4-0.2-1.3-0.7-1.3-0.00.01.2-0.4-1.11.1-1.2-0.1-0.20.60.00.3-0.9
Condit. Reinf. lever presses0.40.61.5-0.30.81.10.6-1.2-0.1-1.0-0.5-0.20.8-0.7-1.11.1-1.1-0.5-0.7-0.5-0.50.5-1.2
Condit. Reinf. active minus inactive responses2.13.28.3-2.20.22.80.0-2.5-1.6-2.9-0.5-0.62.7-1.1-2.32.3-2.5-1.1-1.2-0.5-0.92.0-0.7
Condit. Reinf. active-inactive response ratio1.42.26.5-2.4-0.22.3-0.4-2.2-0.9-2.60.1-0.12.1-0.6-1.91.9-2.2-0.6-0.60.1-0.31.1-1.1
Condit. Reinf. active responses2.63.88.7-2.30.22.90.2-2.5-2.5-3.0-0.7-0.82.9-1.4-2.52.5-2.7-1.3-1.4-0.4-1.12.2-0.5
Condit. Reinf. inactive responses1.11.63.7-0.10.91.31.1-0.9-1.9-1.1-1.3-1.21.4-1.4-1.41.4-1.3-1.4-1.5-0.9-1.31.6-0.0
Condit. Reinf. lever presses1.21.73.6-1.20.51.80.5-1.6-1.7-1.7-0.7-0.91.9-1.2-1.61.6-1.6-1.0-1.1-0.3-1.01.5-0.7
Condit. Reinf. lever reinforcers received2.43.47.5-2.00.32.70.3-2.2-2.5-2.7-0.8-1.02.7-1.4-2.32.3-2.5-1.3-1.4-0.5-1.22.2-0.5
Conditioned reinforcement - actives0.10.30.8-0.5-0.70.0-0.70.3-0.2-0.00.40.7-0.40.60.3-0.30.30.80.70.90.5-0.70.4
Conditioned reinforcement - inactives0.20.62.1-1.0-0.61.2-0.9-0.8-0.0-1.00.91.4-0.10.9-0.30.3-0.40.90.70.30.8-0.5-0.8
Conditioned locomotion0.91.43.7-1.7-1.70.3-1.9-0.1-0.8-0.21.41.4-0.31.20.6-0.60.41.61.41.71.4-1.0-0.1
Patch foraging indifference point 0 sec0.82.25.90.01.21.80.9-2.0-2.4-1.5-0.9-0.91.6-1.3-1.21.2-1.7-1.1-1.5-1.8-1.62.1-1.3
Patch foraging indifference point AUC0.20.51.3-1.1-0.70.2-0.70.01.1-0.11.10.80.10.5-0.20.20.51.01.00.60.7-0.40.4
Delay disc. indifference point, 0s delay0.10.20.60.00.2-0.10.40.2-0.50.1-0.6-0.70.4-0.7-0.30.3-0.1-0.5-0.40.2-0.40.40.4
Delay disc. indifference point, 16s delay0.81.11.6-0.3-1.1-0.8-1.11.00.50.91.21.0-1.11.21.1-1.11.11.21.31.31.2-1.11.1
Delay disc. indifference point, 2s delay0.80.91.9-0.90.11.40.3-1.0-0.9-1.2-0.6-0.51.3-0.9-1.41.4-1.2-0.8-0.8-0.2-0.61.1-0.2
Delay disc. indifference point, 24s delay0.10.20.8-0.8-0.9-0.1-0.80.2-0.1-0.10.50.40.00.50.2-0.20.10.50.60.70.5-0.30.7
Delay disc. indifference point, 4s delay0.20.21.7-0.1-0.8-0.20.00.7-0.10.3-0.2-0.40.0-0.20.2-0.20.3-0.1-0.00.6-0.10.11.3
Delay disc. indifference point, 8s delay0.10.10.30.30.2-0.00.50.10.5-0.0-0.6-0.50.1-0.3-0.10.1-0.2-0.5-0.4-0.2-0.50.20.2
Indifference point function ln k0.41.36.3-0.40.31.20.3-1.4-2.5-1.4-0.8-0.61.2-0.8-1.11.1-1.6-0.9-1.1-0.9-0.81.1-1.1
Indifference point function log k0.41.36.3-0.40.31.20.3-1.4-2.5-1.4-0.8-0.61.2-0.8-1.11.1-1.6-0.9-1.1-0.9-0.81.1-1.1
Patch foraging total patch changes 0 sec0.82.26.3-0.11.01.90.8-2.1-2.5-1.6-0.7-0.71.6-1.2-1.31.3-1.8-1.1-1.5-1.7-1.42.0-1.2
Patch foraging total patch changes 12 sec1.31.73.4-0.41.21.91.0-1.8-1.2-1.3-0.6-0.81.6-1.4-1.51.5-1.3-1.1-1.3-1.2-1.31.8-1.1
Patch foraging total patch changes 18 sec0.10.10.6-0.6-0.10.7-0.1-0.4-0.2-0.50.40.10.6-0.1-0.50.5-0.30.0-0.1-0.1-0.10.60.2
Patch foraging total patch changes 24 sec0.51.63.1-0.20.91.80.7-1.7-1.4-1.5-0.8-0.61.5-1.1-1.51.5-1.5-1.0-1.3-1.5-1.21.7-0.9
Patch foraging total patch changes 6 sec0.40.62.0-0.50.81.10.4-1.4-0.8-0.7-0.1-0.21.0-0.6-0.70.7-0.6-0.1-0.5-0.7-0.71.1-1.4
Patch foraging time to switch 0 sec0.00.10.40.50.7-0.40.40.30.50.6-0.2-0.5-0.1-0.20.3-0.30.5-0.3-0.10.0-0.20.20.1
Patch foraging water rate 0 sec0.00.10.2-0.1-0.30.2-0.3-0.2-0.2-0.30.50.4-0.10.30.1-0.1-0.20.20.1-0.20.20.00.1
Patch foraging water rate 12 sec0.00.00.2-0.1-0.2-0.5-0.20.10.30.1-0.4-0.30.2-0.10.1-0.1-0.00.00.0-0.2-0.10.20.4
Patch foraging water rate 18 sec0.81.96.31.21.50.51.4-0.9-0.4-0.9-1.9-1.31.0-1.2-0.80.8-1.5-1.7-1.7-2.5-1.71.8-0.2
Patch foraging water rate 24 sec0.71.02.41.31.5-0.21.4-0.3-0.1-0.1-1.5-1.50.5-1.0-0.00.0-0.7-1.4-1.4-1.2-1.41.2-0.1
Patch foraging water rate 6 sec0.40.61.9-0.7-0.11.1-0.1-1.1-0.5-1.4-0.5-0.21.0-0.4-1.01.0-1.3-0.5-0.6-0.7-0.40.7-0.2
Seeking ratio, delayed vs. immediate footshock2.73.96.1-0.9-2.3-1.0-2.21.71.71.12.32.0-1.72.31.9-1.91.82.32.52.42.2-1.92.0
Distance traveled before self-admin0.20.40.7-0.6-0.40.60.2-0.2-0.7-0.6-0.5-0.70.9-0.8-0.60.6-0.5-0.6-0.50.3-0.60.70.8
Distance traveled after self-admin0.00.10.20.1-0.0-0.30.10.2-0.20.3-0.1-0.3-0.1-0.40.2-0.20.2-0.1-0.10.5-0.20.10.2
Extensor digitorum longus weight4.216.927.71.3-3.0-5.1-2.64.94.15.13.12.4-4.94.05.3-5.35.23.74.24.03.7-4.53.2
Bone: elastic displacement0.40.51.1-0.50.50.60.1-0.8-0.6-0.8-0.6-0.41.1-0.7-1.01.0-0.6-0.3-0.5-0.9-0.60.6-0.8
Bone: elastic work1.01.33.8-1.30.31.6-0.1-1.7-1.9-1.6-0.30.11.5-0.6-1.41.4-1.2-0.0-0.4-0.8-0.60.9-1.1
Bone: endosteal estimation1.84.412.9-3.6-3.52.1-2.9-0.7-2.7-1.72.92.30.41.7-0.40.4-0.71.71.63.02.2-0.60.9
Bone: endosteal perimeter2.97.120.9-4.4-4.62.5-3.9-1.0-2.7-2.13.73.40.02.6-0.50.5-0.72.52.33.53.1-1.50.5
Epididymis fat weight0.20.82.0-0.1-1.0-0.3-1.00.80.60.31.11.3-1.01.40.6-0.60.40.81.00.51.3-0.90.8
Delta time in closed arm before/after self-admin1.71.65.72.40.6-1.60.51.61.31.90.40.5-2.10.91.5-1.51.50.50.5-0.60.3-1.00.5
Delta time in open arm before/after self-admin0.20.21.4-0.8-0.20.3-0.2-0.3-0.9-0.4-0.2-0.10.2-0.2-0.30.3-0.40.1-0.11.20.1-0.5-0.5
Diff in mean of infusions in LGA sessions0.10.20.6-0.7-0.50.7-0.0-0.4-0.3-0.8-0.3-0.20.7-0.4-0.60.6-0.7-0.3-0.30.2-0.30.30.4
Delay discount exponential model param0.10.20.70.40.80.10.5-0.4-0.3-0.2-0.4-0.30.3-0.4-0.30.3-0.4-0.5-0.5-0.8-0.40.4-0.7
Extinction: sum of active levers before priming0.10.10.7-0.1-0.2-0.1-0.4-0.30.60.3-0.30.1-0.20.20.2-0.20.40.50.20.50.0-0.4-0.9
Active lever presses in extinction session 61.71.76.4-2.5-1.91.2-2.0-1.0-0.5-1.31.61.60.31.0-0.50.5-0.51.51.21.81.4-1.0-0.5
Bone: final force1.52.58.6-0.11.31.91.2-1.6-2.9-1.7-1.0-0.71.6-1.1-1.91.9-1.7-1.2-1.6-1.9-1.51.9-0.4
Bone: final moment2.03.29.1-0.11.52.11.4-1.8-3.0-1.9-1.2-0.91.9-1.4-2.12.1-2.0-1.5-1.8-2.2-1.72.2-0.5
Food consumed during 24 hour testing period0.51.02.1-0.7-1.1-0.4-1.3-0.0-0.90.31.41.4-0.91.40.5-0.50.41.41.30.81.3-1.4-0.8
Glucose0.81.33.81.4-0.1-1.70.11.91.61.60.2-0.0-1.40.61.4-1.41.30.20.50.20.3-0.71.9
Heart weight3.14.910.1-1.2-3.1-0.8-3.21.00.50.82.63.2-2.13.01.9-1.91.63.02.91.72.9-2.50.9
Delay discount hyperbolic model param0.10.10.60.40.7-0.00.4-0.3-0.1-0.0-0.3-0.20.1-0.3-0.10.1-0.2-0.3-0.3-0.8-0.30.2-0.6
Intermittent access intake day 1-15 change0.31.43.51.4-0.1-1.3-0.21.41.01.51.00.7-1.81.21.9-1.91.50.70.70.40.9-1.00.6
Intermittent access intake escalation0.21.13.11.40.0-1.2-0.21.31.11.40.90.6-1.71.11.8-1.81.30.50.50.30.7-0.70.5
Intermittent access intake escalation 20.71.12.81.0-0.5-0.7-0.51.01.01.01.31.1-1.71.41.6-1.61.10.70.80.41.0-0.90.3
Intermitt. access day 1 inactive lever presses0.22.55.5-2.3-1.51.9-1.9-1.8-1.5-1.71.52.3-0.01.3-0.80.8-0.81.61.01.41.6-1.4-2.2
Intermitt. access day 15 inactive lever presses0.52.88.0-2.20.12.6-0.1-2.3-2.8-2.6-0.0-0.12.0-1.0-2.12.1-2.2-0.7-1.00.3-0.31.0-1.7
Intermitt. access escalation Index0.20.61.5-0.1-0.8-0.7-0.70.80.00.80.40.7-1.00.70.7-0.70.90.60.71.11.0-1.2-0.0
Intermittent access day 1 total infusions0.30.82.6-1.1-1.3-0.1-1.20.6-0.2-0.00.70.9-0.40.90.3-0.30.51.21.11.61.0-1.00.8
Intermittent access day 15 total infusions0.82.04.0-0.2-1.2-0.8-1.41.20.21.11.71.5-1.71.61.7-1.71.51.71.62.01.6-1.50.7
Intermittent access terminal intake (last 3 days)0.91.64.7-1.0-1.6-0.1-1.50.8-0.50.31.71.5-1.01.41.0-1.00.81.51.42.21.6-1.30.8
Intermittent access total infusions2.32.76.1-1.1-1.8-0.6-2.01.0-0.10.72.01.9-1.51.91.4-1.41.42.22.12.52.0-1.90.8
Intermittent access day 1 locomotion0.71.33.2-1.6-1.10.4-1.6-0.5-1.3-0.31.71.5-0.31.10.2-0.20.31.81.51.51.2-1.0-0.6
Intermittent access day 15 total locomotion0.31.12.5-0.2-0.8-0.7-1.00.8-0.10.81.61.2-1.11.31.3-1.31.11.51.41.21.1-0.90.8
Intermittent access total locomotion1.31.53.8-1.5-1.40.2-1.7-0.0-1.0-0.12.01.7-0.51.40.6-0.60.51.91.71.71.5-0.90.2
Intermittent access standard deviation0.00.20.80.40.20.2-0.00.30.30.10.50.9-0.90.60.3-0.30.20.50.30.20.6-0.8-0.1
Left kidney weight0.10.42.40.3-0.6-0.3-0.40.90.20.40.60.8-0.51.00.3-0.30.50.50.7-0.80.5-0.11.6
Right kidney weight0.21.73.7-0.7-1.8-0.5-1.81.00.80.61.71.8-0.91.90.9-0.91.11.81.80.31.5-1.11.5
Cocaine induced anxiety0.10.31.61.00.9-0.30.60.11.20.2-0.40.0-0.40.1-0.10.10.1-0.3-0.2-1.3-0.2-0.1-0.1
Post-drug Anxiety0.10.10.7-0.20.00.3-0.3-0.50.6-0.30.30.70.00.5-0.20.2-0.10.40.3-0.80.2-0.1-0.4
Baseline Anxiety0.61.15.2-2.3-1.61.0-1.4-0.9-1.3-1.01.00.90.70.5-0.40.4-0.41.00.81.40.8-0.1-0.2
Tail length0.31.95.9-2.4-1.02.3-1.0-2.1-0.4-2.40.70.91.60.2-1.61.6-1.90.50.2-0.40.20.6-0.8
Length with tail0.62.87.7-2.4-2.31.1-2.8-1.0-0.0-1.02.62.7-0.12.20.1-0.1-0.22.42.10.71.9-0.8-0.4
Length without tail0.52.66.1-0.7-1.8-1.0-2.20.90.81.12.52.1-1.42.31.4-1.41.42.22.30.81.9-1.30.7
Times rat made contact with spout0.20.20.6-0.10.0-0.1-0.4-0.1-0.10.00.30.7-0.40.80.0-0.00.00.70.5-0.30.4-0.8-0.7
Lifetime Intake1.82.35.5-1.5-2.0-0.1-2.10.7-0.20.21.71.9-1.01.81.0-1.01.02.11.92.31.9-1.70.7
Liver weight, left0.50.92.4-1.5-1.11.2-1.2-0.7-1.3-1.21.51.40.31.1-0.70.7-0.50.80.8-0.00.90.10.2
Liver weight, right0.30.62.70.31.10.40.8-0.6-0.7-0.7-0.5-0.20.6-0.2-1.01.0-0.9-0.5-0.6-1.6-0.70.7-0.6
Locomotor activity0.71.13.7-1.6-0.41.9-0.5-1.7-1.5-1.80.20.31.2-0.2-1.11.1-1.6-0.1-0.30.1-0.10.6-0.6
Locomotor testing distance0.51.34.4-1.8-0.72.1-0.6-1.5-1.6-1.90.20.21.4-0.3-1.11.1-1.5-0.2-0.40.6-0.10.80.0
Locomotor testing rearing0.20.62.0-1.30.11.4-0.1-1.2-0.8-1.10.1-0.21.1-0.4-0.70.7-0.9-0.2-0.30.7-0.30.8-0.5
Locomotion in novel chamber0.91.24.9-1.3-0.70.80.1-0.1-1.4-0.9-0.3-1.11.7-1.1-0.90.9-0.8-1.0-0.6-0.1-0.71.72.2
Locomotion in novel chamber post-restriction0.10.31.1-0.3-0.00.6-0.3-0.9-0.9-0.60.50.7-0.00.4-0.30.3-0.30.30.1-0.10.30.1-1.1
Fecal boli incidents, locomotor time 10.00.10.50.60.30.10.4-0.00.4-0.1-0.4-0.30.0-0.2-0.10.1-0.3-0.5-0.5-0.7-0.40.30.1
Change in fecal boli incidents, locomotor task0.10.10.6-0.4-0.80.2-0.40.1-0.3-0.00.20.30.10.30.1-0.10.10.40.40.10.20.00.6
Time >=10cm from walls, locomotor time 10.20.21.50.1-0.1-0.70.30.80.20.3-0.4-0.80.3-0.5-0.10.10.0-0.5-0.2-0.0-0.40.31.2
Bouts of movement, locomotor time 10.20.31.01.00.6-1.00.30.60.10.9-0.3-0.2-0.70.10.5-0.50.6-0.1-0.0-0.10.0-0.6-0.6
Total resting periods, locomotor time 10.30.31.10.90.4-1.10.10.60.30.9-0.10.1-0.80.40.6-0.60.70.20.2-0.10.3-0.8-0.5
Rest time, locomotor task time 10.10.21.40.30.7-0.10.5-0.30.2-0.1-0.6-0.50.3-0.4-0.20.2-0.2-0.5-0.5-0.4-0.40.1-1.2
Distance moved, locomotor task time 10.41.13.4-1.0-1.8-0.2-1.50.70.20.41.31.1-0.61.10.7-0.70.81.31.31.31.2-0.71.4
Vertical activity count, locomotor time 10.10.82.2-0.8-1.5-0.3-1.10.80.10.51.00.8-0.50.80.6-0.60.80.91.01.21.0-0.61.3
Time >=10cm from walls, locomotor time 20.10.31.5-0.7-0.60.6-0.0-0.0-1.0-0.7-0.1-0.20.8-0.3-0.70.7-0.7-0.3-0.2-0.1-0.20.51.2
Bouts of movement, locomotor time 20.10.30.7-0.30.60.70.3-0.8-0.1-0.6-0.5-0.10.6-0.4-0.70.7-0.8-0.3-0.4-0.4-0.30.4-0.8
Total resting periods, locomotor time 20.00.10.60.10.70.30.3-0.50.3-0.3-0.5-0.10.2-0.2-0.30.3-0.4-0.2-0.3-0.4-0.20.2-0.7
Rest time, locomotor task time 20.50.82.00.4-0.3-1.1-0.50.81.01.00.60.9-1.31.00.9-0.91.11.00.90.70.9-1.4-0.4
Distance moved, locomotor task time 20.10.11.1-0.4-0.60.1-0.30.2-0.6-0.10.1-0.10.3-0.2-0.10.1-0.00.00.10.30.00.41.1
Vertical activity count, locomotor time 20.20.41.5-0.60.10.80.2-0.8-1.2-0.7-0.4-0.50.9-0.8-0.70.7-0.8-0.5-0.60.1-0.50.8-0.3
Light reinforcement 10.41.74.5-0.60.71.70.3-2.1-2.1-1.5-0.8-0.31.3-1.0-1.51.5-1.6-0.7-1.1-0.8-0.81.1-2.0
Light reinforcement 20.61.42.8-0.40.61.60.6-1.4-1.6-1.4-0.9-0.51.3-1.0-1.71.7-1.4-1.0-1.2-1.0-0.91.1-0.7
Bone: marrow area1.74.212.4-3.5-3.52.0-2.9-0.7-2.7-1.72.92.30.31.7-0.40.4-0.61.71.62.92.2-0.70.9
Bone: maximum diameter1.02.09.8-2.0-1.42.4-1.0-1.5-3.1-2.11.01.01.00.2-1.51.5-1.60.2-0.10.60.50.4-0.4
Bone: maximum force0.51.07.0-0.9-0.21.7-0.4-1.2-2.7-1.30.50.70.70.2-1.01.0-0.90.2-0.2-0.4-0.00.9-0.2
Bone: maximum moment0.61.27.3-0.90.11.9-0.1-1.4-2.7-1.50.20.31.1-0.1-1.21.2-1.2-0.1-0.5-0.7-0.41.3-0.2
Mean time between licks in bursts0.95.49.60.3-1.8-1.9-2.12.02.82.02.52.6-2.93.12.6-2.62.42.62.71.62.6-2.71.0
Mean num. licks in bursts0.20.61.20.70.90.51.1-0.2-0.9-0.6-0.9-0.80.5-0.7-0.60.6-0.8-1.0-1.0-1.0-0.91.00.4
Cd content in liver1.71.95.82.40.6-2.40.92.21.12.3-0.9-0.9-1.60.01.7-1.71.9-0.4-0.10.1-0.2-0.60.9
Co content in liver0.30.42.2-0.9-1.0-0.7-0.40.80.50.30.0-0.60.5-0.30.2-0.20.40.10.40.90.1-0.11.5
Cu content in liver0.40.52.0-1.4-0.40.9-0.4-0.9-0.5-1.20.00.11.0-0.1-1.01.0-1.10.1-0.00.30.1-0.3-0.7
Fe content in liver0.50.61.51.10.3-0.90.81.00.90.8-1.2-1.20.1-0.90.3-0.30.3-0.7-0.6-0.8-0.90.21.2
K content in liver2.72.65.5-0.71.11.41.4-1.2-0.6-1.8-1.7-1.82.3-2.1-2.12.1-1.9-1.8-1.8-1.1-1.71.6-0.4
Mg content in liver4.95.411.10.92.60.63.1-0.9-0.6-1.3-3.2-3.32.4-3.2-2.22.2-2.1-3.1-3.0-2.1-3.02.1-0.8
Mn content in liver7.78.612.30.62.92.13.0-2.5-2.7-2.6-3.5-2.83.0-3.2-3.33.3-3.1-3.2-3.5-3.3-3.32.9-2.2
Na content in liver0.40.41.0-0.80.50.70.2-0.80.5-0.5-0.7-0.71.0-0.9-0.60.6-0.6-0.4-0.60.5-0.50.3-1.0
Rb content in liver3.33.87.50.62.30.72.5-0.90.1-1.1-2.5-2.72.2-2.5-1.81.8-1.8-2.7-2.4-1.9-2.52.3-0.4
Se content in liver0.50.61.81.10.1-1.40.40.91.21.1-0.5-0.2-0.90.20.7-0.70.80.20.20.10.1-1.2-0.5
Sr content in liver0.90.82.6-0.5-1.5-0.8-1.01.00.10.51.00.5-0.60.80.7-0.70.70.60.91.11.0-0.81.6
Zn content in liver0.20.30.70.20.6-0.00.70.10.6-0.1-0.8-0.80.6-0.5-0.40.4-0.3-0.6-0.5-0.5-0.70.30.2
Bone: minimum diameter2.65.014.4-3.8-3.13.1-2.7-1.9-3.5-2.82.72.61.01.5-1.51.5-1.61.61.21.81.9-0.1-0.0
Time in familiar zone, hab. session 10.80.92.21.1-0.1-1.20.01.01.11.20.60.5-1.50.71.4-1.41.10.60.70.50.6-1.00.3
Time in novel zone, hab. session 10.20.30.9-0.9-0.20.5-0.1-0.3-0.6-0.7-0.2-0.30.9-0.2-0.80.8-0.6-0.4-0.3-0.2-0.30.50.1
Total zone transitions, hab. session 10.81.23.01.0-0.1-1.7-0.31.40.81.60.90.4-1.50.81.6-1.61.70.70.80.40.7-0.90.5
Total locomotion distance, hab. session 10.10.10.4-0.3-0.10.4-0.3-0.3-0.6-0.40.40.20.20.0-0.00.0-0.20.10.0-0.10.10.50.2
Locomotion velocity, hab. session 10.10.10.5-0.5-0.20.5-0.5-0.4-0.7-0.40.60.40.20.1-0.00.0-0.10.20.10.00.20.40.1
Time in familiar zone, hab. session 21.11.23.10.7-0.2-1.2-0.40.91.81.30.91.0-1.41.21.4-1.41.41.31.20.40.8-1.20.4
Time in novel zone, hab. session 21.31.42.6-0.50.51.10.6-0.7-1.5-1.3-1.1-1.21.6-1.3-1.51.5-1.4-1.6-1.4-0.8-1.11.50.1
Total zone transitions, hab. session 20.70.93.11.00.2-1.80.31.70.81.50.0-0.5-0.80.11.2-1.21.30.10.40.20.1-0.41.5
Total locomotion distance, hab. session 20.30.41.40.80.4-1.20.31.00.71.00.0-0.3-0.60.11.0-1.00.90.10.20.00.0-0.30.7
Locomotion velocity, hab. session 20.40.51.61.00.3-1.30.31.20.51.10.0-0.3-0.80.11.1-1.11.00.10.20.10.0-0.30.8
Novel to familiar place preference ratio0.20.20.8-0.6-0.20.9-0.3-0.7-0.5-0.70.30.40.30.4-0.40.4-0.50.20.00.10.10.3-0.5
Novelty place preference0.20.20.8-0.5-0.10.9-0.2-0.6-0.7-0.70.00.20.50.1-0.60.6-0.6-0.1-0.2-0.1-0.10.5-0.4
Time in novel zone, NPP test0.20.20.7-0.4-0.00.8-0.1-0.6-0.9-0.7-0.10.10.50.0-0.60.6-0.7-0.2-0.3-0.3-0.20.5-0.3
Total zone transitions, NPP test0.71.03.61.91.2-1.31.31.30.51.1-0.7-1.1-0.6-0.50.7-0.70.8-1.1-0.7-0.8-0.70.41.1
Total locomotion distance, NPP test0.20.20.50.60.7-0.10.60.1-0.60.0-0.4-0.60.2-0.4-0.20.2-0.2-0.7-0.6-0.7-0.60.70.3
Locomotion velocity, NPP test0.10.10.40.60.6-0.30.40.2-0.00.3-0.0-0.3-0.2-0.00.2-0.20.2-0.4-0.3-0.3-0.20.30.1
Intraocular pressure0.61.02.2-0.6-1.5-0.4-1.20.70.70.61.01.2-0.91.10.6-0.60.71.11.21.31.3-1.40.5
Delta distance traveled before/after self-admin0.20.20.60.70.7-0.50.20.10.10.60.20.3-0.70.20.4-0.40.40.30.2-0.10.2-0.4-0.7
Delta ambulatory time before/after self-admin0.30.61.40.60.2-0.5-0.40.10.50.80.91.1-1.21.00.7-0.70.80.90.80.10.8-0.9-1.0
Parametrial fat weight0.30.72.20.10.21.10.7-0.6-0.8-1.0-0.4-0.40.9-0.5-1.01.0-1.1-0.9-0.8-1.5-0.81.20.5
Pavlov. Cond. lever latency1.01.23.71.90.4-1.90.91.90.11.7-0.9-1.0-1.1-0.41.2-1.21.2-0.6-0.30.0-0.4-0.51.3
Pavlov. Cond. magazine entry latency3.03.910.2-1.41.62.90.7-3.2-1.6-2.6-0.8-0.42.5-1.4-2.42.4-2.5-0.9-1.3-1.5-1.32.1-2.6
Pavlov. Cond. change in total contacts1.71.85.6-1.60.52.10.1-2.4-0.4-2.0-0.20.11.6-0.6-1.81.8-1.9-0.2-0.5-0.3-0.40.7-2.3
Pavlov. Cond. index score1.72.17.3-1.60.72.5-0.1-2.7-0.8-2.10.00.41.7-0.5-1.81.8-1.9-0.1-0.5-0.7-0.41.2-2.3
Pavlov. Cond. latency score1.51.96.4-1.70.52.3-0.2-2.5-0.6-2.00.20.51.6-0.3-1.71.7-1.80.0-0.3-0.6-0.31.1-2.0
Pavlov. Cond. lever contacts1.11.34.0-1.9-0.41.9-0.9-2.0-0.2-1.70.71.01.10.3-1.31.3-1.30.60.30.10.40.4-1.5
Pavlov. Cond. magazine entry number3.84.810.11.1-1.9-3.0-1.33.21.72.71.41.0-2.72.02.7-2.72.81.41.91.81.8-2.42.4
Pavlov. Cond. intertrial magazine entries1.01.22.6-0.4-1.1-0.5-1.20.30.80.61.11.3-1.21.20.9-0.90.91.31.21.61.4-1.6-1.1
Pavlov. Cond. lever-magazine prob. diff.2.12.68.1-1.80.72.70.0-2.8-0.9-2.4-0.10.22.0-0.7-2.12.1-2.1-0.3-0.7-0.7-0.51.4-2.3
Pavlov. Cond. response bias3.64.511.3-1.81.33.30.6-3.4-1.6-2.9-0.8-0.52.8-1.5-2.82.8-2.8-1.0-1.5-1.5-1.32.3-2.3
Pavlov. Cond. lever latency0.50.71.50.7-0.4-1.0-0.40.81.01.10.60.6-1.20.81.0-1.00.90.70.80.30.7-1.00.2
Pavlov. Cond. magazine entry latency0.30.41.10.60.1-1.00.31.00.81.0-0.1-0.4-0.50.00.7-0.70.8-0.00.10.3-0.1-0.20.9
Pavlov. Cond. change in total contacts0.30.82.6-1.5-0.11.1-0.0-1.0-0.7-1.1-0.5-0.81.6-0.9-1.11.1-0.9-0.6-0.60.4-0.50.8-0.5
Pavlov. Cond. index score0.20.20.7-0.7-0.00.50.1-0.3-0.8-0.6-0.3-0.60.9-0.5-0.60.6-0.4-0.4-0.40.2-0.30.60.1
Pavlov. Cond. latency score0.10.20.8-0.8-0.20.5-0.1-0.2-0.9-0.6-0.1-0.40.8-0.4-0.60.6-0.4-0.3-0.30.3-0.20.40.1
Pavlov. Cond. lever contacts0.50.81.6-0.50.61.00.6-0.9-1.0-1.1-0.8-0.81.3-0.9-1.11.1-1.0-0.9-0.9-0.6-0.91.1-0.4
Pavlov. Cond. magazine entry number0.30.41.3-0.7-0.80.7-0.9-0.6-0.2-0.60.81.1-0.20.7-0.20.2-0.40.70.60.30.8-0.6-0.7
Pavlov. Cond. intertrial magazine entries1.02.14.6-2.1-1.42.1-1.5-1.6-2.1-1.81.61.90.41.0-1.31.3-1.20.80.70.71.3-0.5-1.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.5-0.6-0.00.30.1-0.1-0.6-0.4-0.2-0.50.7-0.5-0.40.4-0.3-0.4-0.30.3-0.30.50.3
Pavlov. Cond. response bias0.60.81.4-0.00.90.70.9-0.5-0.4-0.7-1.0-1.11.1-1.1-0.90.9-0.8-1.1-1.1-0.7-1.11.2-0.1
Time in closed arm before self-admin0.81.43.31.31.7-0.01.7-0.70.1-0.2-1.8-1.40.6-1.3-0.70.7-0.7-1.3-1.4-1.8-1.51.0-0.9
Time in closed arm after self-admin2.22.513.13.62.1-2.02.11.51.22.1-1.1-1.2-1.4-0.51.2-1.21.1-0.9-0.8-1.9-1.20.10.5
Time in open arm before self-admin3.34.06.9-0.4-2.6-1.6-2.32.31.51.62.11.7-1.82.32.1-2.12.11.92.31.82.1-1.62.5
Time in open arm after self-admin3.13.48.5-2.7-2.90.3-2.90.1-0.2-0.32.32.3-0.62.00.7-0.70.62.32.32.82.4-1.70.4
Bone: periosteal estimation1.53.513.8-3.1-2.03.0-1.7-1.9-3.7-2.61.81.51.30.7-1.61.6-1.80.70.41.21.00.5-0.3
Bone: periosteal perimeter1.63.29.5-3.1-2.72.1-2.5-1.3-2.3-1.82.32.20.51.6-0.70.7-0.81.61.31.81.7-0.5-0.2
Bone: post-yield work2.23.89.7-1.8-2.80.1-2.80.4-0.10.23.12.7-1.32.61.2-1.20.92.52.52.32.6-1.60.8
Progressive ratio test 1 active lever presses0.50.93.0-1.7-1.30.6-1.4-0.1-1.4-0.60.91.00.00.8-0.00.0-0.01.00.91.71.1-0.70.2
Progressive ratio test 1 breakpoint0.61.13.3-1.8-1.40.8-1.5-0.3-1.4-0.71.11.2-0.00.9-0.10.1-0.11.21.01.81.2-0.9-0.0
Progressive ratio test 1 inactive lever presses0.71.95.0-2.2-1.01.9-1.5-1.8-2.1-1.71.01.60.50.6-1.11.1-1.01.20.71.21.0-0.7-1.8
Progressive ratio test 2 active lever presses0.70.92.9-1.7-1.40.7-1.3-0.2-1.3-0.71.31.00.10.70.0-0.0-0.11.00.91.61.0-0.60.4
Progressive ratio test 2 breakpoint0.70.92.9-1.7-1.50.7-1.3-0.2-1.3-0.61.41.00.10.70.1-0.1-0.11.00.91.71.0-0.50.5
Progressive ratio test 2 inactive lever presses0.51.63.7-1.9-1.51.0-1.7-0.7-0.7-0.81.41.9-0.31.30.0-0.0-0.01.71.21.71.5-1.4-0.8
Incentive Sensitization - Responses0.20.52.2-1.5-1.20.9-0.7-0.2-1.1-0.81.10.20.70.1-0.20.2-0.50.20.31.00.40.30.9
Incentive Sensitization - Breakpoint0.20.51.9-1.4-1.10.8-0.6-0.1-1.0-0.71.00.20.70.0-0.20.2-0.50.20.31.00.30.40.9
Sum of active levers in priming session hrs 5-60.30.31.2-0.5-0.3-0.40.10.60.70.3-0.4-0.90.4-0.60.1-0.10.2-0.4-0.21.1-0.30.00.9
Progressive ratio0.10.41.00.51.00.30.9-0.7-0.5-0.1-0.5-0.60.3-0.8-0.30.3-0.3-0.7-0.8-0.3-0.70.7-0.8
Food seeking constrained by brief footshock0.10.10.3-0.3-0.10.1-0.2-0.2-0.40.20.50.4-0.20.1-0.20.20.20.40.30.50.4-0.4-0.5
Seeking ratio, punishment vs. effort0.20.51.2-1.1-1.00.1-1.10.2-0.2-0.11.01.0-0.20.7-0.00.00.21.01.00.90.9-0.90.0
Retroperitoneal fat weight0.10.33.10.2-0.20.10.20.50.5-0.20.1-0.20.3-0.0-0.20.2-0.4-0.4-0.1-0.9-0.30.71.8
Reaction time number correct0.10.52.7-0.6-1.6-0.2-1.10.5-0.3-0.10.10.6-0.40.50.2-0.2-0.00.50.60.60.7-0.71.3
Reaction time mean minus median0.10.54.2-0.70.30.80.2-1.4-0.3-0.80.10.10.6-0.2-0.70.7-0.90.0-0.20.1-0.1-0.2-2.1
Reaction time mean minus median AUC0.21.53.5-0.11.20.91.2-1.5-0.6-1.2-1.2-1.11.3-1.4-1.31.3-1.5-1.2-1.3-0.8-1.20.7-1.9
Reaction time num false alarms0.81.33.2-1.3-1.80.4-1.7-0.3-1.6-0.31.51.7-0.61.20.1-0.10.21.41.21.31.5-1.3-0.6
Reaction time num false alarms AUC0.51.12.6-1.2-1.50.7-1.5-0.5-1.5-0.51.41.6-0.41.0-0.10.1-0.21.21.01.01.3-1.1-0.8
Reaction time trials correct on left0.10.52.7-0.6-1.6-0.2-1.10.5-0.3-0.10.10.6-0.40.50.2-0.2-0.00.50.60.60.7-0.71.3
Reaction time trials on left0.10.42.4-0.6-1.6-0.1-1.00.3-0.4-0.30.00.5-0.20.4-0.00.0-0.20.40.50.50.6-0.61.2
Reaction time mean1.02.25.2-0.61.51.41.3-2.0-0.8-1.4-1.3-1.21.8-1.6-1.91.9-1.6-1.2-1.4-0.7-1.41.1-2.3
Reaction time mean AUC0.92.25.4-0.51.51.21.4-1.9-0.9-1.2-1.5-1.41.8-1.7-1.81.8-1.5-1.2-1.5-0.6-1.51.1-2.3
Median of all reaction times1.52.34.2-0.71.51.51.3-2.0-0.9-1.4-1.4-1.32.0-1.7-2.02.0-1.6-1.3-1.5-0.7-1.51.3-2.1
Reaction time omissions3.86.111.3-1.71.32.91.3-3.4-2.9-3.1-1.5-1.63.3-2.4-3.23.2-3.4-2.0-2.2-1.3-1.92.3-2.4
Reaction time false alarm rate0.40.61.7-0.7-0.60.6-0.8-0.6-1.0-0.31.21.2-0.30.7-0.00.0-0.00.80.60.70.9-0.7-1.3
Reaction time premature initiation rate0.20.41.2-0.7-0.41.0-0.6-1.1-0.1-0.60.70.90.10.6-0.20.2-0.30.70.40.10.4-0.0-1.1
Reaction time premature initiations0.20.51.5-0.9-1.20.9-1.1-0.9-0.5-0.70.81.2-0.10.7-0.20.2-0.40.90.70.40.7-0.4-0.5
Std. dev. reaction times0.72.36.2-0.31.71.31.5-2.0-0.8-1.3-1.3-1.31.7-1.6-1.71.7-1.7-1.3-1.5-1.0-1.51.0-2.5
Reaction time trials completed0.10.42.4-0.6-1.6-0.1-1.00.3-0.4-0.30.00.5-0.20.4-0.00.0-0.20.40.50.50.6-0.61.2
Reaction time trials AUC0.10.42.3-0.6-1.5-0.1-0.90.3-0.6-0.3-0.00.5-0.20.3-0.00.0-0.20.40.50.50.5-0.61.2
Run reversals in cocaine runway, females1.31.42.40.2-0.7-0.9-0.91.21.21.11.51.3-1.51.61.4-1.41.31.21.40.81.5-1.40.3
Run reversals in cocaine runway, males0.30.31.2-0.6-0.41.0-0.2-0.1-0.5-0.70.20.40.50.1-0.90.9-0.5-0.0-0.0-0.40.10.41.1
Latency to leave start box in cocaine runway1.01.44.10.8-0.8-1.2-0.51.81.51.20.80.7-1.41.21.5-1.51.20.71.00.30.8-0.72.0
Latency to leave start box in cocaine runway, F4.55.68.60.6-2.3-2.1-1.92.92.22.32.22.0-2.82.82.9-2.92.62.12.41.72.3-2.22.8
Latency to leave start box in cocaine runway, M2.82.64.40.51.91.11.9-1.1-0.9-1.2-1.8-1.81.8-2.1-1.61.6-1.7-1.8-1.9-2.0-2.12.0-0.4
Std. dev. time between licks in bursts0.71.42.8-0.1-1.4-0.8-1.11.01.70.81.20.9-1.21.31.5-1.51.01.21.31.21.1-1.01.2
Total sessions with >9 infusions2.73.37.0-1.4-2.5-1.0-2.51.50.40.81.61.8-1.42.11.5-1.51.62.32.22.72.1-2.21.4
Short access day 1 total inactive lever presses0.30.62.6-1.6-1.40.8-1.2-0.2-1.0-0.90.30.60.70.6-0.60.6-0.30.50.50.60.50.10.5
Short access day 10 total inactive lever presses0.21.23.7-1.7-0.81.7-1.0-1.7-1.1-1.60.71.20.60.6-0.90.9-1.00.60.20.50.6-0.4-1.9
Short access day 1 total infusions0.30.61.9-1.3-1.40.5-1.20.1-0.4-0.7-0.10.70.00.7-0.30.3-0.10.70.51.30.7-0.90.2
Short access day 10 total infusions0.71.23.0-1.3-1.60.1-1.70.4-0.4-0.01.11.4-0.61.30.6-0.60.51.51.41.71.4-1.30.5
Short access total infusions0.81.23.1-1.5-1.80.2-1.70.4-0.3-0.30.71.3-0.41.30.3-0.30.41.41.21.71.3-1.30.6
Short access day 1 locomotion0.71.14.1-2.0-1.80.7-1.8-0.5-1.2-0.70.81.00.30.8-0.20.2-0.01.20.91.60.9-0.6-0.1
Short access day 10 total locomotion0.51.84.6-2.1-1.31.3-1.8-1.4-1.4-1.02.21.90.11.3-0.30.3-0.41.81.41.41.3-0.8-1.3
Short access total locomotion2.53.88.7-2.7-2.60.6-3.0-0.4-1.0-0.52.72.7-0.72.20.7-0.70.62.82.42.72.4-1.9-0.2
One hour access (0.3 mA shock)0.30.41.00.2-0.3-0.5-0.21.0-0.20.60.80.3-0.70.60.8-0.80.80.50.50.90.5-0.31.0
Compulsive drug intake0.30.51.20.60.9-0.10.9-0.20.50.1-0.8-1.10.6-0.8-0.30.3-0.2-0.9-0.7-1.1-1.01.1-0.1
One hour access (shock baseline)0.71.93.8-0.8-1.5-0.6-1.61.1-0.30.71.91.6-1.31.61.1-1.11.21.71.71.91.7-1.51.1
Social response proportion2.33.06.6-1.7-2.6-0.4-2.50.50.90.32.12.4-1.02.41.0-1.00.92.42.31.52.2-2.10.6
Social responses0.20.30.7-0.8-0.40.5-0.7-0.6-0.1-0.30.70.90.10.6-0.10.1-0.20.80.50.00.5-0.4-0.8
Social time1.62.67.5-2.7-2.40.9-2.5-0.80.1-0.92.02.3-0.01.7-0.10.1-0.22.11.91.62.0-1.5-0.3
Soleus weight0.51.43.1-0.8-1.5-0.6-1.60.50.80.51.81.5-1.01.60.7-0.70.81.51.51.31.6-1.5-0.0
Bone: stiffness0.10.21.30.5-0.1-0.00.00.4-1.10.50.40.3-0.50.50.4-0.40.50.20.10.10.10.10.7
Tibialis anterior weight0.82.84.8-1.0-2.1-1.0-2.10.90.50.92.11.9-1.52.01.4-1.41.32.22.22.02.1-2.00.7
Time to tail flick, vehicle, before self-admin1.01.23.11.51.4-0.61.80.5-0.10.5-1.2-1.70.4-1.4-0.20.2-0.1-1.6-1.3-1.3-1.41.10.6
Time to tail flick, vehicle, after self-admin0.20.41.2-0.60.41.00.2-1.1-0.6-0.80.1-0.00.7-0.4-0.70.7-0.6-0.1-0.4-0.2-0.30.4-0.9
Time to tail flick, test, before self-admin0.30.31.70.4-0.3-1.3-0.11.20.20.80.0-0.2-0.50.30.7-0.70.60.10.40.40.3-0.60.7
Time to tail flick, test, after self-admin0.00.00.2-0.2-0.20.1-0.10.1-0.4-0.30.10.2-0.10.2-0.20.2-0.3-0.1-0.00.10.2-0.4-0.2
Delta time to tail flick, vehicle, before/after SA0.90.92.8-1.7-0.31.6-0.8-1.5-0.9-1.40.81.00.70.3-0.80.8-0.90.60.30.60.5-0.1-1.3
Delta time to tail flick, test, before/after SA0.40.61.7-1.3-0.51.3-0.4-1.0-0.8-1.20.10.11.0-0.3-0.90.9-0.9-0.1-0.30.20.00.5-0.3
Tibia length0.30.82.21.50.4-0.9-0.00.80.41.00.41.0-1.31.11.0-1.00.71.00.8-1.20.2-0.51.0
Ambulatory time before self-admin0.10.41.0-0.8-0.40.80.1-0.5-0.9-0.9-0.5-0.61.0-0.9-0.70.7-0.7-0.4-0.50.3-0.60.70.3
Ambulatory time after self-admin0.00.10.4-0.20.00.4-0.0-0.5-0.4-0.2-0.20.10.1-0.2-0.20.2-0.10.2-0.00.1-0.10.2-0.6
Bone: tissue strength0.70.73.11.70.8-0.80.51.01.31.2-0.30.2-1.20.50.9-0.91.10.00.1-0.9-0.0-0.30.3
Total heroin consumption1.01.23.1-1.4-0.21.40.2-0.9-0.9-1.5-0.8-0.91.8-1.3-1.51.5-1.4-1.0-0.90.2-0.71.10.2
Bone: trabecular number2.03.79.2-1.70.73.00.3-2.9-2.5-2.8-0.8-0.22.5-1.2-2.62.6-2.3-0.9-1.2-1.6-1.22.0-1.4
Bone: trabecular spacing1.42.13.91.1-0.3-1.9-0.31.91.82.01.00.7-2.01.31.9-1.91.91.01.21.11.1-1.50.7
Bone: trabecular thickness0.60.93.7-1.6-1.01.3-1.2-1.2-1.9-1.10.50.90.70.4-0.70.7-0.60.70.40.20.50.1-0.5
Bone: trabecular tissue density0.50.93.31.41.8-0.01.5-0.30.60.2-1.2-0.90.2-0.6-0.30.3-0.1-1.1-1.1-1.6-1.10.9-0.8
Water consumed over 24 hours0.10.22.00.60.3-0.30.20.1-1.40.1-0.30.2-0.30.2-0.40.4-0.2-0.1-0.1-0.8-0.0-0.4-0.3
Number of responses in last shaping day1.41.85.3-1.5-1.70.7-2.0-0.3-0.5-0.31.82.3-0.81.70.4-0.40.41.91.51.51.9-1.4-0.5