Hub : Genes

Gfap

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Gfap 0.08 0.04 4.8e-08 0.03 0.06 0.05 0.04 2.2e-04 6.1e-07 1.1e-06 5.9e-05
2 IL mRNA stability Gfap 0.34 0.13 3.5e-04 0.06 0.13 0.17 0.14 1.6e-02 5.9e-04 7.2e-05 3.2e-04
3 IC gene expression Gfap 0.2 0.09 2.5e-06 0.07 0.15 0.14 0.13 6.7e-04 1.1e-06 2.4e-06 3.2e-06
4 Brain gene expression Gfap 0.21 0.11 5.3e-14 0.12 0.13 0.15 0.13 1.5e-11 4.2e-12 6.7e-14 4.5e-12
5 NAcc mRNA stability Gfap 0.28 0.08 0.0e+00 0.27 0.28 0.28 0.28 5.6e-41 1.0e-41 5.1e-43 1.1e-42
6 PL gene expression Gfap 0.18 0.07 1.7e-16 0.14 0.16 0.17 0.14 1.6e-15 5.3e-17 5.7e-18 2.6e-15
7 OFC gene expression Gfap 0.23 0.11 4.6e-04 0.11 0.08 0.14 0.12 1.2e-03 7.2e-03 2.8e-04 1.1e-03
8 PL mRNA stability Gfap 0.26 0.08 0.0e+00 0.24 0.24 0.26 0.26 1.9e-25 4.3e-26 2.4e-28 1.0e-28
9 BLA mRNA stability Gfap 0.34 0.1 0.0e+00 0.28 0.3 0.29 0.28 2.8e-15 2.5e-16 1.2e-15 3.3e-15
10 BLA gene expression Gfap 0.18 0.07 1.7e-08 0.12 0.13 0.12 0.12 9.4e-07 3.3e-07 9.5e-07 5.5e-07
11 IC mRNA stability Gfap 0.32 0.11 1.6e-12 0.13 0.26 0.26 0.27 3.4e-06 2.6e-11 2.2e-11 1.2e-11
12 NAcc gene expression Gfap 0.07 0.03 1.8e-10 0.07 0.06 0.07 0.06 2.4e-11 2.3e-09 3.0e-10 1.5e-09
13 RMTg mRNA stability Gfap 0.21 0.09 1.4e-04 0.14 0.05 0.07 0.08 1.2e-04 1.5e-02 5.3e-03 3.3e-03
14 IL gene expression Gfap 0.2 0.12 2.3e-03 0.08 0.06 0.04 0.08 5.2e-03 1.4e-02 3.2e-02 6.7e-03
15 LHb mRNA stability Gfap 0.61 0.12 2.2e-11 0.24 0.41 0.3 0.39 2.3e-06 8.5e-11 5.6e-08 3.3e-10
16 Brain mRNA stability Gfap 0.51 0.09 0.0e+00 0.34 0.57 0.56 0.56 1.5e-32 6.5e-64 5.0e-62 2.1e-63
17 OFC mRNA stability Gfap 0.47 0.14 4.5e-06 0.07 0.17 0.15 0.14 9.9e-03 7.2e-05 1.9e-04 3.9e-04
18 pVTA mRNA stability Gfap 0.5 0.09 0.0e+00 0.5 0.6 0.6 0.6 6.4e-46 5.7e-60 2.2e-59 2.9e-59
19 Adipose gene expression Gfap 0.03 0.02 4.6e-03 0 0 -0 -0 2.9e-01 7.7e-02 5.9e-01 4.0e-01
20 pVTA gene expression Gfap 0.07 0.05 2.6e-03 0.01 0.01 0.03 0.03 2.3e-02 2.2e-02 2.2e-03 1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.32.35.1-1.0-0.92.22.2-0.42.32.0-0.8-0.21.9-0.92.0-2.01.8-0.7-1.1-1.5-1.01.61.3
Area under the delay curve0.10.10.5-0.30.6-0.2-0.30.4-0.5-0.20.30.1-0.20.2-0.30.3-0.30.30.30.70.3-0.3-0.7
BMI with tail2.07.013.50.22.6-1.8-0.92.5-2.2-2.23.33.2-3.33.7-2.92.9-2.53.13.12.13.1-3.0-1.3
BMI without tail1.75.311.6-1.22.8-0.3-0.72.9-0.7-0.73.23.4-2.23.4-2.02.0-1.43.23.02.13.0-2.4-0.7
Body weight2.39.923.6-2.34.1-0.2-0.54.4-0.7-0.64.94.8-2.54.6-2.22.2-1.74.54.22.54.1-3.0-0.7
Weight adjusted by age0.20.31.4-1.01.2-0.2-0.00.9-0.30.10.60.20.10.3-0.20.2-0.10.30.51.00.6-0.2-1.0
Bone surface2.13.813.0-2.70.83.33.60.92.73.10.40.82.1-0.22.4-2.42.5-0.1-0.5-0.4-0.11.30.7
Bone volume1.62.912.4-1.90.22.83.50.42.32.6-0.00.41.9-0.52.1-2.12.1-0.4-0.8-0.8-0.41.40.8
Breakpoint value in progressive ratio session0.30.31.2-1.10.50.8-0.10.20.40.9-0.5-0.30.8-0.50.7-0.70.8-0.2-0.30.7-0.20.1-0.1
Number of licking bursts1.01.63.4-0.61.2-0.9-1.11.6-0.5-1.01.41.5-1.11.6-1.11.1-1.31.71.71.21.6-1.80.8
Context. condit. distance diff. score1.82.26.41.00.7-2.0-1.80.3-2.4-2.10.80.2-1.51.0-1.91.9-2.20.81.10.60.6-0.9-2.5
Locomotion velocity, session 10.40.40.90.3-0.70.40.5-0.60.20.5-0.6-0.70.6-0.40.7-0.70.4-0.9-0.8-0.9-0.71.0-0.4
Locomotion distance, session 10.20.31.00.6-1.00.20.2-0.70.20.0-0.4-0.40.1-0.40.3-0.3-0.1-0.7-0.7-0.7-0.50.70.6
Locomotion velocity, session 21.92.24.40.9-1.80.5-0.3-2.00.20.6-1.8-2.01.3-1.71.1-1.11.1-2.1-1.8-1.7-1.92.0-0.9
Locomotion distance, session 20.60.92.60.7-1.60.50.3-1.20.80.5-0.9-0.90.7-0.90.7-0.70.6-1.2-1.2-1.1-1.01.21.1
Locomotion velocity, session 30.10.10.60.3-0.3-0.00.8-0.0-0.1-0.0-0.1-0.00.00.10.2-0.2-0.0-0.2-0.2-0.7-0.20.4-0.6
Locomotion distance, session 30.20.20.5-0.20.2-0.4-0.00.5-0.3-0.50.50.4-0.40.6-0.30.3-0.70.60.60.40.5-0.40.0
Stereotopy head waving bouts, day 30.70.82.11.4-0.9-0.20.7-1.1-0.4-0.0-1.3-1.10.1-0.70.1-0.10.4-1.3-1.2-1.2-1.11.0-0.9
Stereotopy head waving duration, day 30.40.51.51.2-0.7-0.40.4-0.9-0.5-0.3-1.0-1.0-0.1-0.7-0.10.10.2-1.0-0.9-0.7-0.80.7-0.8
Locomotion velocity, session 70.60.73.41.4-0.2-1.1-0.6-0.6-1.3-1.0-0.5-0.5-0.6-0.0-0.70.7-0.8-0.2-0.1-0.9-0.50.1-1.8
Locomotion distance, session 70.30.41.90.9-0.3-0.8-0.6-0.6-1.0-0.8-0.2-0.6-0.3-0.2-0.60.6-0.6-0.3-0.1-0.4-0.40.3-1.4
Stereotopy head waving bouts, day 71.01.12.20.2-0.80.70.5-1.10.51.1-1.4-1.01.1-1.11.3-1.31.5-1.2-1.2-1.3-1.10.8-0.6
Stereotopy head waving duration, day 71.21.43.30.8-1.30.20.5-1.60.20.7-1.8-1.40.9-1.51.2-1.21.3-1.5-1.5-1.5-1.40.8-0.6
Locomotion velocity, session 80.70.82.21.00.3-0.8-0.50.4-1.1-1.01.01.0-1.51.2-1.11.1-1.20.50.7-0.10.8-0.6-0.8
Locomotion distance, session 80.50.71.91.4-0.8-1.0-1.0-0.9-1.2-1.1-0.3-0.8-0.4-0.4-0.70.7-1.0-0.6-0.4-0.5-0.50.5-1.2
Degree of sensitization distance0.20.21.90.20.6-0.3-0.50.2-0.7-0.30.50.1-0.30.4-0.70.7-0.30.20.40.10.20.1-1.4
Degree of sensitization stereotypy0.70.71.50.1-0.80.30.1-1.00.30.8-1.2-0.91.0-1.01.1-1.11.2-1.0-0.9-1.1-0.90.5-0.5
Conditioned locomotion0.00.00.60.00.0-0.0-0.70.1-0.1-0.2-0.2-0.00.10.0-0.10.1-0.10.10.1-0.1-0.10.1-0.1
Cocaine response after cond. corrected0.10.11.1-0.1-0.10.1-0.70.1-0.00.10.40.30.10.30.1-0.10.30.30.3-0.7-0.00.2-1.1
Cocaine response after cond. not corrected0.50.62.4-0.2-0.80.7-0.5-0.50.70.8-0.3-0.21.0-0.31.0-1.01.0-0.3-0.3-1.6-0.71.0-0.7
Cocaine response before conditioning1.01.21.90.0-1.21.00.4-1.01.11.1-1.1-0.81.2-1.11.4-1.41.1-1.2-1.2-1.3-1.01.10.9
Saline control response0.30.41.0-0.70.50.6-0.20.80.60.30.61.0-0.30.8-0.10.10.10.80.50.80.7-0.61.0
Bone: connectivity density2.13.37.4-1.7-0.52.72.5-0.32.52.6-0.7-0.42.4-1.22.5-2.52.3-1.0-1.3-1.2-1.11.81.0
Bone: cortical apparent density4.05.415.53.1-3.9-0.7-1.1-3.70.4-0.6-3.4-3.20.7-2.80.7-0.70.5-2.8-2.8-2.5-2.91.81.9
Bone: cortical area1.42.19.5-1.0-0.22.33.1-0.12.02.10.00.21.4-0.51.9-1.91.9-0.4-0.9-0.9-0.61.21.0
Bone: cortical porosity4.04.414.5-3.81.83.43.32.02.63.11.71.81.90.62.1-2.12.21.00.60.71.00.70.1
Bone: cortical porosity2.83.18.9-3.02.02.42.82.21.62.12.22.30.81.31.1-1.11.21.51.20.81.40.1-0.6
Bone: cortical thickness1.83.08.21.4-2.80.61.0-2.21.40.7-1.9-1.61.2-1.71.4-1.41.3-1.6-1.9-2.9-2.21.81.4
Bone: cortical thickness3.74.46.80.3-2.41.21.7-2.02.01.5-2.5-2.32.5-2.52.0-2.02.2-2.1-2.4-2.5-2.62.51.2
Bone: cortical tissue density4.05.415.23.0-3.9-0.6-1.1-3.60.4-0.6-3.4-3.20.8-2.80.7-0.70.5-2.8-2.9-2.4-2.91.81.9
Condit. Reinf. active minus inactive responses0.50.62.8-1.70.61.00.60.61.01.00.30.20.9-0.10.6-0.60.70.30.21.00.30.00.9
Condit. Reinf. active-inactive response ratio0.10.21.1-1.10.20.3-0.20.20.20.30.1-0.30.7-0.30.3-0.30.2-0.00.00.90.10.20.1
Condit. Reinf. active responses0.40.61.7-1.30.11.30.50.21.21.1-0.00.01.0-0.30.9-0.91.0-0.0-0.20.5-0.10.50.8
Condit. Reinf. inactive responses0.50.61.40.2-0.61.21.0-0.51.00.9-0.6-0.20.6-0.50.8-0.80.9-0.6-0.8-1.0-0.71.00.5
Incentive salience index mean0.60.82.5-1.60.31.40.60.21.31.3-0.00.01.2-0.41.1-1.11.2-0.1-0.20.60.00.30.8
Condit. Reinf. lever presses0.40.61.5-0.3-0.81.10.1-0.61.21.0-0.5-0.20.8-0.71.1-1.11.1-0.5-0.7-0.5-0.50.51.1
Condit. Reinf. active minus inactive responses2.43.28.3-2.2-0.22.81.5-0.02.52.9-0.5-0.62.7-1.12.3-2.32.5-1.1-1.2-0.5-0.92.00.5
Condit. Reinf. active-inactive response ratio1.92.26.5-2.40.22.30.80.42.22.60.1-0.12.1-0.61.9-1.92.2-0.6-0.60.1-0.31.11.0
Condit. Reinf. active responses2.73.88.7-2.3-0.22.92.4-0.22.53.0-0.7-0.82.9-1.42.5-2.52.7-1.3-1.4-0.4-1.12.20.4
Condit. Reinf. inactive responses1.21.53.3-0.1-0.91.31.8-1.10.91.1-1.3-1.21.4-1.41.4-1.41.3-1.4-1.5-0.9-1.31.6-0.1
Condit. Reinf. lever presses1.21.73.6-1.2-0.51.81.6-0.51.61.7-0.7-0.91.9-1.21.6-1.61.6-1.0-1.1-0.3-1.01.50.7
Condit. Reinf. lever reinforcers received2.43.47.5-2.0-0.32.72.4-0.32.22.7-0.9-1.02.7-1.42.3-2.32.5-1.3-1.4-0.5-1.22.20.3
Conditioned reinforcement - actives0.20.30.8-0.50.70.00.20.7-0.30.00.40.7-0.40.6-0.30.3-0.30.80.70.90.5-0.7-0.4
Conditioned reinforcement - inactives0.40.62.1-1.00.61.20.30.90.81.00.91.4-0.10.90.3-0.30.40.90.70.30.8-0.50.6
Conditioned locomotion1.01.43.7-1.71.70.30.91.90.10.21.41.4-0.31.2-0.60.6-0.41.61.41.71.4-1.00.1
Patch foraging indifference point 0 sec1.22.36.30.0-1.21.82.5-1.02.01.5-0.9-0.91.6-1.31.2-1.21.7-1.1-1.5-1.8-1.62.11.2
Patch foraging indifference point AUC0.30.41.3-1.10.70.2-1.00.7-0.00.11.10.80.10.50.2-0.2-0.51.01.00.60.7-0.4-0.4
Delay disc. indifference point, 0s delay0.10.20.60.0-0.2-0.10.3-0.3-0.2-0.1-0.6-0.70.4-0.70.3-0.30.1-0.5-0.40.2-0.40.4-0.4
Delay disc. indifference point, 16s delay1.01.11.6-0.31.1-0.8-0.51.1-1.0-0.91.21.0-1.11.2-1.11.1-1.11.21.31.31.2-1.1-1.0
Delay disc. indifference point, 2s delay0.80.91.9-0.9-0.11.40.9-0.31.01.2-0.6-0.51.3-0.91.4-1.41.2-0.8-0.8-0.2-0.61.10.2
Delay disc. indifference point, 24s delay0.20.20.8-0.80.9-0.10.00.8-0.20.10.50.40.00.5-0.20.2-0.10.50.60.70.5-0.3-0.7
Delay disc. indifference point, 4s delay0.20.21.5-0.10.8-0.2-0.0-0.0-0.7-0.3-0.2-0.40.0-0.2-0.20.2-0.3-0.1-0.00.6-0.10.1-1.2
Delay disc. indifference point, 8s delay0.10.10.40.3-0.2-0.0-0.6-0.5-0.10.0-0.6-0.50.1-0.30.1-0.10.2-0.5-0.4-0.2-0.50.2-0.2
Indifference point function ln k0.71.36.1-0.4-0.31.22.5-0.31.41.4-0.8-0.61.2-0.81.1-1.11.6-0.9-1.1-0.9-0.81.11.0
Indifference point function log k0.71.36.1-0.4-0.31.22.5-0.31.41.4-0.8-0.61.2-0.81.1-1.11.6-0.9-1.1-0.9-0.81.11.0
Patch foraging total patch changes 0 sec1.22.27.0-0.1-1.01.92.6-0.82.11.6-0.7-0.71.6-1.21.3-1.31.8-1.1-1.5-1.7-1.42.01.2
Patch foraging total patch changes 12 sec1.31.73.4-0.4-1.21.91.2-1.01.81.3-0.6-0.81.6-1.41.5-1.51.3-1.1-1.3-1.2-1.31.81.1
Patch foraging total patch changes 18 sec0.10.10.6-0.60.10.70.30.10.40.50.40.10.6-0.10.5-0.50.30.0-0.1-0.1-0.10.6-0.1
Patch foraging total patch changes 24 sec1.01.73.1-0.2-0.91.81.5-0.71.71.5-0.8-0.61.5-1.11.5-1.51.5-1.0-1.3-1.5-1.21.70.9
Patch foraging total patch changes 6 sec0.40.62.2-0.5-0.81.10.8-0.41.40.7-0.1-0.21.0-0.60.7-0.70.6-0.1-0.5-0.7-0.71.11.5
Patch foraging time to switch 0 sec0.10.10.40.5-0.7-0.4-0.6-0.4-0.3-0.6-0.2-0.5-0.1-0.2-0.30.3-0.5-0.3-0.10.0-0.20.2-0.0
Patch foraging water rate 0 sec0.00.10.2-0.10.30.20.30.30.20.30.50.4-0.10.3-0.10.10.20.20.1-0.20.20.0-0.2
Patch foraging water rate 12 sec0.00.00.2-0.10.2-0.5-0.40.2-0.1-0.1-0.4-0.30.2-0.1-0.10.10.00.00.0-0.2-0.10.2-0.4
Patch foraging water rate 18 sec1.21.96.31.2-1.50.50.5-1.40.90.9-1.9-1.31.0-1.20.8-0.81.5-1.7-1.7-2.5-1.71.8-0.0
Patch foraging water rate 24 sec0.71.02.41.3-1.5-0.2-0.0-1.40.30.1-1.5-1.50.5-1.10.0-0.00.7-1.4-1.4-1.2-1.41.20.1
Patch foraging water rate 6 sec0.40.61.9-0.70.11.10.50.11.11.4-0.5-0.21.0-0.41.0-1.01.3-0.5-0.6-0.7-0.40.7-0.0
Seeking ratio, delayed vs. immediate footshock3.13.86.1-0.92.3-1.0-1.72.2-1.8-1.12.32.0-1.72.3-1.91.9-1.82.32.52.42.2-1.9-1.9
Distance traveled before self-admin0.30.30.7-0.60.40.60.5-0.20.20.6-0.5-0.70.9-0.80.6-0.60.5-0.6-0.50.3-0.60.7-0.8
Distance traveled after self-admin0.00.00.20.10.0-0.30.1-0.1-0.2-0.3-0.1-0.3-0.1-0.4-0.20.2-0.2-0.1-0.10.5-0.20.1-0.1
Extensor digitorum longus weight4.316.827.71.33.0-5.1-4.22.6-4.9-5.13.12.4-4.94.0-5.35.3-5.23.74.24.03.7-4.5-2.6
Bone: elastic displacement0.40.51.1-0.5-0.50.60.6-0.10.80.8-0.6-0.41.1-0.71.0-1.00.6-0.3-0.5-0.9-0.60.60.7
Bone: elastic work1.01.34.3-1.3-0.31.62.10.11.71.6-0.30.11.5-0.61.4-1.41.2-0.0-0.4-0.8-0.60.91.0
Bone: endosteal estimation2.04.412.9-3.63.52.12.92.90.71.72.92.30.41.70.4-0.40.71.71.63.02.2-0.6-0.9
Bone: endosteal perimeter3.47.220.9-4.44.62.52.93.91.02.13.73.40.02.60.5-0.50.72.52.33.53.1-1.5-0.5
Epididymis fat weight0.20.82.0-0.11.0-0.3-0.41.0-0.8-0.31.11.3-1.01.4-0.60.6-0.40.81.00.51.3-0.9-0.9
Delta time in closed arm before/after self-admin1.71.55.72.4-0.6-1.6-1.2-0.5-1.6-1.90.40.5-2.10.9-1.51.5-1.50.50.5-0.60.3-1.0-0.5
Delta time in open arm before/after self-admin0.20.21.4-0.80.20.30.70.20.30.4-0.2-0.10.2-0.20.3-0.30.40.1-0.11.20.1-0.50.5
Diff in mean of infusions in LGA sessions0.20.20.6-0.70.50.70.20.00.40.8-0.3-0.20.7-0.40.6-0.60.7-0.3-0.30.2-0.30.3-0.4
Delay discount exponential model param0.20.20.70.4-0.80.10.3-0.50.40.2-0.4-0.30.3-0.40.3-0.30.4-0.5-0.5-0.8-0.40.40.6
Extinction: sum of active levers before priming0.10.11.0-0.10.2-0.1-0.70.40.3-0.3-0.30.1-0.20.2-0.20.2-0.40.50.20.50.0-0.41.0
Active lever presses in extinction session 61.81.76.4-2.51.91.20.52.01.01.31.61.60.31.00.5-0.50.51.51.21.81.4-1.00.6
Bone: final force1.62.59.4-0.1-1.31.93.1-1.21.61.7-1.0-0.71.6-1.11.9-1.91.7-1.2-1.6-1.9-1.51.90.1
Bone: final moment2.03.29.9-0.1-1.52.13.1-1.41.81.9-1.2-0.91.9-1.42.1-2.12.0-1.5-1.8-2.2-1.72.20.2
Food consumed during 24 hour testing period0.71.02.1-0.71.1-0.41.01.30.0-0.31.41.4-0.91.4-0.50.5-0.41.41.30.81.3-1.40.9
Glucose0.81.33.81.40.1-1.7-1.7-0.1-1.9-1.60.2-0.0-1.40.6-1.41.4-1.30.20.50.20.3-0.7-1.8
Heart weight3.24.910.1-1.23.1-0.8-0.13.2-1.0-0.82.63.2-2.13.0-1.91.9-1.63.02.91.72.9-2.5-0.9
Delay discount hyperbolic model param0.10.10.60.4-0.7-0.00.2-0.40.30.0-0.3-0.20.1-0.30.1-0.10.2-0.3-0.3-0.8-0.30.20.5
Intermittent access intake day 1-15 change0.71.43.51.40.1-1.3-1.00.2-1.4-1.51.00.7-1.81.2-1.91.9-1.50.70.70.40.9-1.0-0.5
Intermittent access intake escalation0.61.13.11.4-0.0-1.2-1.00.2-1.3-1.40.90.6-1.71.1-1.81.8-1.30.50.50.30.7-0.7-0.4
Intermittent access intake escalation 20.91.12.81.00.5-0.7-0.90.5-1.0-1.01.31.1-1.71.4-1.61.6-1.10.70.80.41.0-0.9-0.2
Intermitt. access day 1 inactive lever presses0.72.55.5-2.31.51.91.71.91.81.71.52.3-0.01.30.8-0.80.81.61.01.41.6-1.42.2
Intermitt. access day 15 inactive lever presses1.42.87.7-2.2-0.12.62.80.12.32.6-0.0-0.12.0-1.02.1-2.12.2-0.7-1.00.3-0.31.01.5
Intermitt. access escalation Index0.40.61.5-0.10.8-0.7-0.00.7-0.8-0.80.40.7-1.00.7-0.70.7-0.90.60.71.11.0-1.20.1
Intermittent access day 1 total infusions0.50.82.6-1.11.3-0.10.21.2-0.60.00.70.9-0.40.9-0.30.3-0.51.21.11.61.0-1.0-0.7
Intermittent access day 15 total infusions1.32.04.0-0.21.2-0.8-0.21.4-1.2-1.11.71.5-1.71.6-1.71.7-1.51.71.62.01.6-1.5-0.4
Intermittent access terminal intake (last 3 days)1.21.64.7-1.01.6-0.10.51.5-0.8-0.31.71.5-1.01.4-1.01.0-0.81.51.42.21.6-1.3-0.7
Intermittent access total infusions2.32.76.1-1.11.8-0.60.12.0-1.0-0.72.01.9-1.51.9-1.41.4-1.42.22.12.52.0-1.9-0.7
Intermittent access day 1 locomotion1.01.33.2-1.61.10.41.41.60.50.31.71.5-0.31.1-0.20.2-0.31.81.51.51.2-1.00.7
Intermittent access day 15 total locomotion0.61.12.5-0.20.8-0.70.21.0-0.8-0.81.61.2-1.11.3-1.31.3-1.11.51.41.21.1-0.9-0.7
Intermittent access total locomotion1.31.53.8-1.51.40.21.11.70.00.12.01.7-0.51.4-0.60.6-0.51.91.71.71.5-0.9-0.1
Intermittent access standard deviation0.10.20.80.4-0.20.2-0.20.0-0.3-0.10.50.9-0.90.7-0.30.3-0.20.50.30.20.6-0.80.1
Left kidney weight0.10.53.10.30.6-0.30.10.4-0.9-0.40.60.8-0.51.0-0.30.3-0.50.50.7-0.80.5-0.1-1.8
Right kidney weight0.41.73.7-0.71.8-0.5-0.51.8-1.0-0.61.71.8-0.91.9-0.90.9-1.11.81.80.31.5-1.1-1.7
Cocaine induced anxiety0.20.31.61.0-0.9-0.3-1.0-0.6-0.1-0.2-0.40.0-0.40.10.1-0.1-0.1-0.3-0.2-1.3-0.2-0.10.0
Post-drug Anxiety0.10.10.7-0.2-0.00.3-0.40.30.50.30.30.70.00.50.2-0.20.10.40.3-0.80.2-0.10.3
Baseline Anxiety0.91.15.2-2.31.61.01.31.40.91.01.00.90.70.50.4-0.40.41.00.81.40.8-0.10.3
Tail length0.51.95.9-2.41.02.30.61.02.12.40.70.91.60.21.6-1.61.90.50.2-0.40.20.60.5
Length with tail0.62.87.6-2.42.31.10.42.81.01.02.62.7-0.12.2-0.10.10.22.42.10.71.9-0.80.3
Length without tail0.82.66.1-0.71.8-1.0-0.62.2-0.9-1.12.52.1-1.42.3-1.41.4-1.42.22.30.81.9-1.3-0.6
Times rat made contact with spout0.20.20.6-0.1-0.0-0.10.30.40.1-0.00.30.7-0.40.8-0.00.0-0.00.70.5-0.30.4-0.80.6
Lifetime Intake1.92.35.5-1.52.0-0.10.32.1-0.7-0.21.71.9-1.01.8-1.01.0-1.02.11.92.31.9-1.7-0.6
Liver weight, left0.61.02.7-1.51.11.21.61.20.71.21.51.40.31.10.7-0.70.50.80.8-0.00.90.1-0.5
Liver weight, right0.30.62.70.3-1.10.40.8-0.80.60.7-0.5-0.20.6-0.21.0-1.00.9-0.5-0.6-1.6-0.70.70.3
Locomotor activity0.71.13.7-1.60.41.91.60.51.71.80.20.31.2-0.21.1-1.11.6-0.1-0.30.1-0.10.60.5
Locomotor testing distance0.71.34.4-1.80.72.11.60.61.51.90.20.21.4-0.31.1-1.11.5-0.2-0.40.6-0.10.8-0.0
Locomotor testing rearing0.30.62.0-1.3-0.11.40.60.11.21.10.1-0.21.1-0.40.7-0.70.9-0.2-0.30.7-0.30.80.6
Locomotion in novel chamber0.91.25.2-1.30.70.81.2-0.10.10.9-0.3-1.11.7-1.20.9-0.90.8-1.0-0.6-0.1-0.71.7-2.3
Locomotion in novel chamber post-restriction0.20.31.2-0.30.00.61.10.30.90.60.50.7-0.00.40.3-0.30.30.30.1-0.10.30.11.0
Fecal boli incidents, locomotor time 10.10.10.50.6-0.30.1-0.4-0.40.00.1-0.4-0.30.0-0.20.1-0.10.3-0.5-0.5-0.7-0.40.3-0.1
Change in fecal boli incidents, locomotor task0.10.10.6-0.40.80.20.40.4-0.10.00.20.30.10.3-0.10.1-0.10.40.40.10.20.0-0.7
Time >=10cm from walls, locomotor time 10.20.21.70.10.1-0.7-0.3-0.3-0.8-0.3-0.4-0.80.3-0.50.1-0.1-0.0-0.5-0.2-0.0-0.40.3-1.3
Bouts of movement, locomotor time 10.30.31.01.0-0.6-1.0-0.1-0.3-0.6-0.9-0.3-0.2-0.70.1-0.50.5-0.6-0.1-0.0-0.10.0-0.60.6
Total resting periods, locomotor time 10.30.31.10.9-0.4-1.1-0.3-0.1-0.6-0.9-0.00.1-0.80.4-0.60.6-0.70.20.2-0.10.3-0.80.6
Rest time, locomotor task time 10.20.21.50.3-0.7-0.1-0.2-0.50.30.1-0.6-0.50.3-0.40.2-0.20.2-0.5-0.5-0.4-0.40.11.2
Distance moved, locomotor task time 10.71.13.4-1.01.8-0.2-0.21.5-0.7-0.41.31.1-0.61.0-0.70.7-0.81.31.31.31.2-0.7-1.4
Vertical activity count, locomotor time 10.30.82.2-0.81.5-0.3-0.11.1-0.8-0.51.00.8-0.50.8-0.60.6-0.80.91.01.21.0-0.6-1.3
Time >=10cm from walls, locomotor time 20.20.41.9-0.70.60.61.00.00.00.7-0.1-0.20.8-0.30.7-0.70.7-0.3-0.2-0.1-0.20.5-1.4
Bouts of movement, locomotor time 20.20.30.7-0.3-0.60.70.1-0.30.80.6-0.5-0.10.6-0.40.7-0.70.8-0.3-0.4-0.4-0.30.40.7
Total resting periods, locomotor time 20.10.10.50.1-0.70.3-0.2-0.30.50.3-0.5-0.10.2-0.20.3-0.30.4-0.2-0.3-0.4-0.20.20.7
Rest time, locomotor task time 20.60.82.00.40.3-1.1-1.00.5-0.8-1.00.60.9-1.31.0-0.90.9-1.11.00.90.70.9-1.40.5
Distance moved, locomotor task time 20.10.11.1-0.40.60.10.60.3-0.20.10.1-0.10.3-0.20.1-0.10.00.00.10.30.00.4-1.1
Vertical activity count, locomotor time 20.30.41.2-0.6-0.10.81.1-0.20.80.7-0.4-0.50.9-0.80.7-0.70.8-0.5-0.60.1-0.50.80.4
Light reinforcement 10.71.74.6-0.6-0.71.72.1-0.32.11.5-0.8-0.31.3-1.01.5-1.51.6-0.7-1.1-0.8-0.81.12.0
Light reinforcement 20.91.42.8-0.4-0.61.61.7-0.61.41.4-0.9-0.51.3-1.01.7-1.71.4-1.0-1.2-1.0-0.91.10.6
Bone: marrow area2.04.312.4-3.53.52.02.82.90.71.72.92.30.31.70.4-0.40.61.71.62.92.2-0.7-0.9
Bone: maximum diameter1.12.110.6-2.01.42.43.31.01.52.11.01.01.00.21.5-1.51.60.2-0.10.60.50.40.2
Bone: maximum force0.61.08.2-0.90.21.72.90.41.21.30.50.70.70.21.0-1.00.90.2-0.2-0.4-0.00.90.0
Bone: maximum moment0.71.38.5-0.9-0.11.92.90.11.41.50.20.31.1-0.11.2-1.21.2-0.1-0.5-0.7-0.41.3-0.0
Mean time between licks in bursts2.25.39.60.31.8-1.9-2.52.1-2.0-2.02.52.6-2.93.1-2.62.6-2.42.62.71.62.6-2.7-0.8
Mean num. licks in bursts0.40.61.20.7-0.90.50.9-1.10.20.6-0.9-0.80.5-0.70.6-0.60.8-1.0-1.0-1.0-0.91.0-0.6
Cd content in liver1.71.95.82.4-0.6-2.4-1.3-0.9-2.2-2.3-0.9-0.9-1.60.0-1.71.7-1.9-0.4-0.10.1-0.2-0.6-0.6
Co content in liver0.30.41.9-0.91.0-0.7-0.80.4-0.8-0.30.0-0.60.5-0.3-0.20.2-0.40.10.40.90.1-0.1-1.4
Cu content in liver0.40.52.0-1.40.40.90.50.40.91.20.00.11.0-0.11.0-1.01.10.1-0.00.30.1-0.30.6
Fe content in liver0.50.71.51.1-0.3-0.9-1.0-0.8-1.0-0.8-1.2-1.20.1-0.9-0.30.3-0.3-0.7-0.6-0.8-0.90.2-1.2
K content in liver2.72.65.5-0.7-1.11.40.3-1.41.21.8-1.7-1.82.3-2.12.1-2.11.9-1.8-1.8-1.1-1.71.60.2
Mg content in liver5.35.411.10.9-2.60.60.2-3.10.91.3-3.2-3.32.4-3.22.2-2.22.1-3.1-3.0-2.1-3.02.10.6
Mn content in liver7.78.512.30.6-2.92.12.5-3.02.52.6-3.5-2.83.0-3.23.3-3.33.1-3.2-3.5-3.3-3.32.91.9
Na content in liver0.40.41.1-0.8-0.50.7-0.7-0.20.80.5-0.7-0.71.0-0.90.6-0.60.6-0.4-0.60.5-0.50.31.0
Rb content in liver3.33.87.50.6-2.30.7-0.4-2.50.91.1-2.5-2.72.2-2.51.8-1.81.8-2.7-2.4-1.9-2.52.30.3
Se content in liver0.50.61.81.1-0.1-1.4-1.3-0.4-0.9-1.1-0.5-0.2-0.90.2-0.70.7-0.80.20.20.10.1-1.20.6
Sr content in liver0.90.82.4-0.51.5-0.8-0.21.0-1.0-0.51.00.5-0.60.8-0.70.7-0.70.60.91.11.0-0.8-1.6
Zn content in liver0.20.30.70.2-0.6-0.0-0.7-0.7-0.10.1-0.8-0.80.6-0.50.4-0.40.3-0.6-0.5-0.5-0.70.3-0.3
Bone: minimum diameter2.85.114.4-3.83.13.13.82.71.92.82.72.61.01.51.5-1.51.61.61.21.81.9-0.1-0.2
Time in familiar zone, hab. session 10.90.92.21.10.1-1.2-1.20.0-1.0-1.20.60.5-1.50.7-1.41.4-1.10.60.70.50.6-1.0-0.1
Time in novel zone, hab. session 10.30.30.9-0.90.20.50.60.10.30.7-0.2-0.30.9-0.20.8-0.80.6-0.4-0.3-0.2-0.30.5-0.3
Total zone transitions, hab. session 10.81.23.01.00.1-1.7-0.70.3-1.4-1.60.90.4-1.50.8-1.61.6-1.70.70.80.40.7-0.9-0.3
Total locomotion distance, hab. session 10.10.10.5-0.30.10.40.70.30.30.40.40.20.20.00.0-0.00.20.10.0-0.10.10.5-0.2
Locomotion velocity, hab. session 10.10.10.7-0.50.20.50.80.50.40.40.60.40.20.10.0-0.00.10.20.10.00.20.4-0.1
Time in familiar zone, hab. session 21.11.22.50.70.2-1.2-1.60.4-0.9-1.30.91.0-1.41.2-1.41.4-1.41.31.20.40.8-1.2-0.3
Time in novel zone, hab. session 21.41.42.6-0.5-0.51.11.4-0.60.71.3-1.1-1.21.6-1.31.5-1.51.4-1.6-1.4-0.8-1.11.5-0.3
Total zone transitions, hab. session 20.70.93.11.0-0.2-1.8-1.0-0.3-1.7-1.50.0-0.5-0.80.1-1.21.2-1.30.10.40.20.1-0.4-1.4
Total locomotion distance, hab. session 20.30.41.40.8-0.4-1.2-0.7-0.3-1.0-1.00.0-0.3-0.60.1-1.01.0-0.90.10.20.00.0-0.3-0.6
Locomotion velocity, hab. session 20.40.51.61.0-0.3-1.3-0.6-0.3-1.2-1.10.0-0.3-0.80.1-1.11.1-1.00.10.20.10.0-0.3-0.7
Novel to familiar place preference ratio0.20.20.8-0.60.20.90.50.30.70.70.30.40.30.40.4-0.40.50.20.00.10.10.30.4
Novelty place preference0.20.20.8-0.50.10.90.70.20.60.70.00.20.50.10.6-0.60.6-0.1-0.2-0.1-0.10.50.3
Time in novel zone, NPP test0.20.20.8-0.40.00.80.90.10.60.7-0.10.10.50.00.6-0.60.7-0.2-0.3-0.3-0.20.50.1
Total zone transitions, NPP test0.71.03.61.9-1.2-1.3-0.6-1.3-1.3-1.1-0.7-1.1-0.6-0.5-0.70.7-0.8-1.1-0.7-0.8-0.70.4-1.0
Total locomotion distance, NPP test0.20.20.50.6-0.7-0.10.6-0.6-0.1-0.0-0.4-0.60.2-0.40.2-0.20.2-0.7-0.6-0.7-0.60.7-0.3
Locomotion velocity, NPP test0.10.10.40.6-0.6-0.30.0-0.4-0.2-0.3-0.0-0.3-0.2-0.0-0.20.2-0.2-0.4-0.3-0.3-0.20.3-0.1
Intraocular pressure0.71.02.2-0.61.5-0.4-0.61.2-0.7-0.61.01.2-0.91.1-0.60.6-0.71.11.21.31.3-1.4-0.6
Delta distance traveled before/after self-admin0.20.20.60.7-0.7-0.5-0.1-0.2-0.1-0.60.20.3-0.70.2-0.40.4-0.40.30.2-0.10.2-0.40.8
Delta ambulatory time before/after self-admin0.50.61.40.6-0.2-0.5-0.30.4-0.1-0.80.91.1-1.21.0-0.70.7-0.80.90.80.10.8-0.91.0
Parametrial fat weight0.30.82.20.1-0.21.11.0-0.70.61.0-0.4-0.40.9-0.51.0-1.01.1-0.9-0.8-1.5-0.81.2-0.8
Pavlov. Cond. lever latency1.01.23.71.9-0.4-1.9-0.3-0.9-1.9-1.7-0.9-1.0-1.1-0.4-1.21.2-1.2-0.6-0.30.0-0.4-0.5-1.2
Pavlov. Cond. magazine entry latency3.03.810.2-1.4-1.62.91.7-0.73.22.6-0.8-0.42.5-1.42.4-2.42.5-0.9-1.3-1.5-1.32.12.4
Pavlov. Cond. change in total contacts1.71.85.6-1.6-0.52.10.4-0.12.42.0-0.20.11.6-0.61.8-1.81.9-0.2-0.5-0.3-0.40.72.2
Pavlov. Cond. index score1.72.17.3-1.6-0.72.50.90.12.72.10.00.41.7-0.51.8-1.81.9-0.1-0.5-0.7-0.41.22.1
Pavlov. Cond. latency score1.51.86.4-1.7-0.52.30.80.22.52.00.20.51.6-0.31.7-1.71.80.0-0.3-0.6-0.31.11.9
Pavlov. Cond. lever contacts1.11.34.0-1.90.41.90.40.92.01.70.71.01.10.31.3-1.31.30.60.30.10.40.41.4
Pavlov. Cond. magazine entry number3.84.810.11.11.9-3.0-1.71.3-3.2-2.71.41.0-2.72.0-2.72.7-2.81.41.91.81.8-2.4-2.2
Pavlov. Cond. intertrial magazine entries1.01.22.6-0.41.1-0.5-0.71.2-0.3-0.61.11.3-1.21.2-0.90.9-0.91.31.21.61.4-1.61.4
Pavlov. Cond. lever-magazine prob. diff.2.12.68.1-1.8-0.72.71.1-0.02.82.4-0.10.22.0-0.72.1-2.12.1-0.3-0.7-0.7-0.51.42.1
Pavlov. Cond. response bias3.64.511.3-1.8-1.33.31.7-0.63.42.9-0.8-0.52.8-1.52.8-2.82.8-1.0-1.5-1.5-1.32.32.1
Pavlov. Cond. lever latency0.50.71.50.70.4-1.0-0.90.4-0.8-1.10.60.6-1.20.8-1.01.0-0.90.70.80.30.7-1.0-0.1
Pavlov. Cond. magazine entry latency0.30.41.10.6-0.1-1.0-0.9-0.3-1.0-1.0-0.1-0.4-0.50.0-0.70.7-0.8-0.00.10.3-0.1-0.2-0.7
Pavlov. Cond. change in total contacts0.50.82.6-1.50.11.10.50.01.01.1-0.5-0.81.6-0.91.1-1.10.9-0.6-0.60.4-0.50.80.6
Pavlov. Cond. index score0.20.20.7-0.70.00.50.6-0.10.30.6-0.3-0.60.9-0.50.6-0.60.4-0.4-0.40.2-0.30.6-0.1
Pavlov. Cond. latency score0.20.20.7-0.80.20.50.80.10.20.6-0.1-0.40.8-0.40.6-0.60.4-0.3-0.30.3-0.20.4-0.1
Pavlov. Cond. lever contacts0.60.81.6-0.5-0.61.00.9-0.60.91.1-0.8-0.81.3-0.91.1-1.11.0-0.9-0.9-0.6-0.91.10.3
Pavlov. Cond. magazine entry number0.30.41.3-0.70.80.70.40.90.60.60.81.1-0.20.70.2-0.20.40.70.60.30.8-0.60.6
Pavlov. Cond. intertrial magazine entries1.42.15.8-2.11.42.12.41.51.61.81.61.90.41.01.3-1.31.20.80.70.71.3-0.51.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.5-0.60.00.30.5-0.10.10.4-0.2-0.50.7-0.50.4-0.40.3-0.4-0.30.3-0.30.5-0.2
Pavlov. Cond. response bias0.60.81.4-0.0-0.90.70.3-0.90.50.7-1.0-1.11.1-1.10.9-0.90.8-1.1-1.1-0.7-1.11.20.1
Time in closed arm before self-admin1.11.43.31.3-1.7-0.0-0.1-1.70.70.2-1.8-1.40.6-1.30.7-0.70.7-1.3-1.4-1.8-1.51.00.8
Time in closed arm after self-admin2.32.513.13.6-2.1-2.0-1.2-2.1-1.5-2.1-1.1-1.2-1.4-0.5-1.21.2-1.1-0.9-0.8-1.9-1.20.1-0.5
Time in open arm before self-admin3.63.96.9-0.42.6-1.6-1.52.3-2.3-1.62.11.7-1.82.3-2.12.1-2.11.92.31.82.1-1.6-2.4
Time in open arm after self-admin3.13.48.5-2.72.90.30.32.9-0.10.32.32.3-0.62.0-0.70.7-0.62.32.32.82.4-1.7-0.3
Bone: periosteal estimation1.73.515.2-3.12.03.03.91.71.92.61.81.51.30.71.6-1.61.80.70.41.21.00.50.1
Bone: periosteal perimeter1.93.29.5-3.12.72.12.52.51.31.82.32.20.51.60.7-0.70.81.61.31.81.7-0.50.1
Bone: post-yield work2.63.89.7-1.82.80.10.32.8-0.4-0.23.12.7-1.32.6-1.21.2-0.92.52.52.32.6-1.6-0.8
Progressive ratio test 1 active lever presses0.70.93.0-1.71.30.61.31.40.10.60.91.00.00.80.0-0.00.01.00.91.71.1-0.7-0.2
Progressive ratio test 1 breakpoint0.91.13.3-1.81.40.81.41.50.30.71.11.2-0.00.90.1-0.10.11.21.01.81.2-0.90.1
Progressive ratio test 1 inactive lever presses1.31.95.0-2.21.01.92.21.51.81.71.01.60.50.61.1-1.11.01.20.71.21.0-0.71.8
Progressive ratio test 2 active lever presses0.80.92.9-1.71.40.71.31.30.20.71.31.00.10.7-0.00.00.11.00.91.61.0-0.6-0.4
Progressive ratio test 2 breakpoint0.80.92.9-1.71.50.71.31.30.20.61.31.00.10.7-0.10.10.11.00.91.71.0-0.5-0.4
Progressive ratio test 2 inactive lever presses1.01.63.7-1.91.51.00.81.70.70.81.41.9-0.31.3-0.00.00.01.71.21.71.5-1.40.8
Incentive Sensitization - Responses0.40.52.2-1.51.20.91.00.70.20.81.10.20.70.10.2-0.20.50.20.31.00.40.3-0.9
Incentive Sensitization - Breakpoint0.40.51.9-1.41.10.80.90.60.10.71.00.20.70.00.2-0.20.50.20.31.00.30.4-0.9
Sum of active levers in priming session hrs 5-60.30.31.2-0.50.3-0.4-1.1-0.1-0.6-0.3-0.4-0.90.4-0.6-0.10.1-0.2-0.4-0.21.1-0.30.0-0.7
Progressive ratio0.20.41.00.5-1.00.30.5-0.90.70.1-0.5-0.60.3-0.80.3-0.30.3-0.7-0.8-0.3-0.70.70.9
Food seeking constrained by brief footshock0.10.10.3-0.30.10.10.30.20.2-0.20.50.4-0.20.10.2-0.2-0.20.40.30.50.4-0.40.6
Seeking ratio, punishment vs. effort0.40.51.2-1.11.00.10.21.1-0.20.11.01.0-0.20.70.0-0.0-0.21.01.00.90.9-0.9-0.1
Retroperitoneal fat weight0.10.33.80.20.20.1-0.4-0.2-0.50.20.1-0.20.3-0.00.2-0.20.4-0.4-0.1-0.9-0.30.7-2.0
Reaction time number correct0.20.52.7-0.61.6-0.20.41.1-0.50.10.10.6-0.40.5-0.20.20.00.50.60.60.7-0.7-1.4
Reaction time mean minus median0.20.54.4-0.7-0.30.80.3-0.21.40.80.10.10.6-0.20.7-0.70.90.0-0.20.1-0.1-0.22.1
Reaction time mean minus median AUC0.61.43.3-0.1-1.20.90.5-1.21.51.2-1.2-1.11.3-1.41.3-1.31.5-1.2-1.3-0.8-1.20.71.8
Reaction time num false alarms1.01.43.2-1.31.80.41.71.70.30.31.51.7-0.61.2-0.10.1-0.21.41.21.31.5-1.30.7
Reaction time num false alarms AUC0.71.12.8-1.21.50.71.71.50.50.51.41.6-0.41.00.1-0.10.21.21.01.01.3-1.10.8
Reaction time trials correct on left0.20.52.7-0.61.6-0.20.41.1-0.50.10.10.6-0.40.5-0.20.20.00.50.60.60.7-0.7-1.4
Reaction time trials on left0.20.42.4-0.61.6-0.10.51.0-0.30.30.00.5-0.20.40.0-0.00.20.40.50.50.6-0.6-1.3
Reaction time mean1.42.25.1-0.6-1.51.40.6-1.32.01.4-1.4-1.21.8-1.61.9-1.91.6-1.2-1.4-0.7-1.41.12.2
Reaction time mean AUC1.42.25.4-0.5-1.51.20.7-1.41.91.2-1.5-1.41.8-1.71.8-1.81.5-1.2-1.5-0.6-1.51.12.3
Median of all reaction times1.62.34.2-0.7-1.51.50.7-1.32.01.4-1.4-1.32.0-1.72.0-2.01.6-1.3-1.5-0.7-1.51.32.0
Reaction time omissions4.16.011.3-1.7-1.32.92.7-1.33.43.1-1.5-1.63.3-2.43.2-3.23.4-2.0-2.2-1.3-1.92.32.2
Reaction time false alarm rate0.40.61.9-0.70.60.61.00.80.60.31.21.2-0.30.70.0-0.00.00.80.60.70.9-0.71.4
Reaction time premature initiation rate0.30.41.2-0.70.41.00.30.61.10.60.70.90.10.60.2-0.20.30.70.40.10.4-0.01.1
Reaction time premature initiations0.30.61.5-0.91.20.90.71.10.90.70.81.2-0.10.70.2-0.20.40.90.70.40.7-0.40.5
Std. dev. reaction times1.22.26.1-0.3-1.71.30.6-1.52.01.3-1.3-1.31.7-1.61.7-1.71.7-1.3-1.5-1.0-1.51.02.5
Reaction time trials completed0.20.42.4-0.61.6-0.10.51.0-0.30.30.00.5-0.20.40.0-0.00.20.40.50.50.6-0.6-1.3
Reaction time trials AUC0.20.42.3-0.61.5-0.10.70.9-0.30.3-0.00.5-0.20.30.0-0.00.20.40.50.50.5-0.6-1.3
Run reversals in cocaine runway, females1.41.42.40.20.7-0.9-1.00.9-1.2-1.11.51.3-1.51.6-1.41.4-1.31.21.40.81.5-1.4-0.2
Run reversals in cocaine runway, males0.30.31.7-0.60.41.00.70.20.10.70.20.40.50.10.9-0.90.5-0.0-0.0-0.40.10.4-1.3
Latency to leave start box in cocaine runway1.21.44.40.80.8-1.2-1.30.6-1.8-1.20.80.7-1.41.2-1.51.5-1.20.71.00.30.8-0.7-2.1
Latency to leave start box in cocaine runway, F4.85.58.60.62.3-2.1-2.01.9-2.9-2.32.22.0-2.82.8-2.92.9-2.62.12.41.72.3-2.2-2.7
Latency to leave start box in cocaine runway, M2.82.64.40.5-1.91.10.8-1.91.11.2-1.8-1.81.8-2.11.6-1.61.7-1.8-1.9-2.0-2.12.00.2
Std. dev. time between licks in bursts1.01.32.6-0.11.4-0.8-1.61.1-1.0-0.81.20.9-1.21.3-1.51.5-1.01.21.31.21.1-1.0-1.1
Total sessions with >9 infusions2.73.37.0-1.42.5-1.0-0.42.5-1.5-0.81.61.8-1.42.1-1.51.5-1.62.32.22.72.1-2.2-1.3
Short access day 1 total inactive lever presses0.50.62.6-1.61.40.81.11.10.20.90.30.60.70.60.6-0.60.30.50.50.60.50.1-0.6
Short access day 10 total inactive lever presses0.51.23.6-1.70.81.71.21.01.71.60.71.20.60.60.9-0.91.00.60.20.50.6-0.41.9
Short access day 1 total infusions0.40.61.9-1.31.40.50.41.2-0.10.7-0.10.70.00.70.3-0.30.10.70.51.30.7-0.9-0.3
Short access day 10 total infusions1.01.23.0-1.31.60.10.41.7-0.40.01.11.4-0.61.3-0.60.6-0.51.51.41.71.4-1.3-0.5
Short access total infusions0.91.23.1-1.51.80.20.31.7-0.40.30.71.3-0.41.3-0.30.3-0.41.41.21.71.3-1.3-0.6
Short access day 1 locomotion0.91.14.1-2.01.80.71.21.80.50.70.81.00.30.80.2-0.20.01.20.91.60.9-0.60.1
Short access day 10 total locomotion1.01.94.6-2.11.31.31.51.71.41.02.11.90.11.30.3-0.30.41.81.41.41.3-0.81.3
Short access total locomotion3.23.88.7-2.72.60.61.13.00.40.52.72.7-0.72.2-0.70.7-0.62.82.42.72.4-1.90.3
One hour access (0.3 mA shock)0.30.40.90.20.3-0.50.10.3-1.0-0.60.80.3-0.70.6-0.80.8-0.80.50.50.90.5-0.3-0.9
Compulsive drug intake0.40.51.20.6-0.9-0.1-0.5-0.90.2-0.1-0.8-1.10.6-0.80.3-0.30.2-0.9-0.7-1.1-1.01.10.1
One hour access (shock baseline)1.21.93.8-0.81.5-0.60.31.6-1.1-0.71.91.6-1.31.6-1.11.1-1.21.71.71.91.7-1.5-1.0
Social response proportion2.63.06.6-1.72.6-0.4-0.82.5-0.5-0.32.12.4-1.02.4-1.01.0-0.92.42.31.52.2-2.1-0.5
Social responses0.20.30.7-0.80.40.50.20.70.60.30.70.90.10.60.1-0.10.20.80.50.00.5-0.40.7
Social time1.92.67.5-2.72.40.90.12.50.80.92.02.3-0.01.70.1-0.10.22.11.91.62.0-1.50.4
Soleus weight0.51.43.1-0.81.5-0.6-0.71.6-0.5-0.51.81.5-1.01.6-0.70.7-0.81.51.51.31.6-1.50.0
Bone: stiffness0.10.21.40.50.1-0.01.2-0.0-0.4-0.50.40.3-0.50.5-0.40.4-0.50.20.10.10.10.1-0.7
Tibialis anterior weight0.82.84.8-1.02.1-1.0-0.42.1-0.9-0.92.11.9-1.52.0-1.41.4-1.32.22.22.02.1-2.0-0.5
Time to tail flick, vehicle, before self-admin1.21.23.11.5-1.4-0.6-0.1-1.8-0.5-0.5-1.2-1.70.4-1.40.2-0.20.1-1.6-1.3-1.3-1.41.1-0.7
Time to tail flick, vehicle, after self-admin0.30.41.2-0.6-0.41.00.6-0.21.10.80.1-0.00.7-0.40.7-0.70.6-0.1-0.4-0.2-0.30.41.0
Time to tail flick, test, before self-admin0.30.31.70.40.3-1.3-0.30.1-1.2-0.80.0-0.2-0.50.3-0.70.7-0.60.10.40.40.3-0.6-0.6
Time to tail flick, test, after self-admin0.00.00.1-0.20.20.10.40.1-0.10.30.10.2-0.10.20.2-0.20.3-0.1-0.00.10.2-0.40.1
Delta time to tail flick, vehicle, before/after SA1.00.92.8-1.70.31.61.00.81.51.40.81.00.70.30.8-0.80.90.60.30.60.5-0.11.3
Delta time to tail flick, test, before/after SA0.50.51.7-1.30.51.30.80.41.01.20.10.11.0-0.30.9-0.90.9-0.1-0.30.20.00.50.2
Tibia length0.30.82.21.5-0.4-0.9-0.1-0.0-0.8-1.00.41.0-1.31.1-1.01.0-0.71.00.8-1.20.2-0.5-1.1
Ambulatory time before self-admin0.30.41.0-0.80.40.80.7-0.10.50.9-0.5-0.61.0-0.90.7-0.70.7-0.4-0.50.3-0.60.7-0.3
Ambulatory time after self-admin0.10.10.5-0.2-0.00.40.40.00.50.2-0.20.10.1-0.20.2-0.20.10.2-0.00.1-0.10.20.7
Bone: tissue strength0.70.73.11.7-0.8-0.8-1.1-0.5-1.0-1.2-0.30.2-1.20.5-0.90.9-1.10.00.1-0.9-0.0-0.3-0.3
Total heroin consumption1.01.23.1-1.40.21.40.7-0.20.91.5-0.8-0.91.8-1.31.5-1.51.4-1.0-0.90.2-0.71.1-0.3
Bone: trabecular number2.33.79.2-1.7-0.73.02.7-0.32.92.8-0.8-0.22.5-1.22.6-2.62.3-0.9-1.2-1.6-1.22.01.1
Bone: trabecular spacing1.62.13.91.10.3-1.9-1.90.3-1.9-2.01.10.7-2.01.3-1.91.9-1.91.01.21.11.1-1.5-0.5
Bone: trabecular thickness0.70.94.3-1.61.01.32.11.21.21.10.50.90.70.40.7-0.70.60.70.40.20.50.10.5
Bone: trabecular tissue density0.60.93.31.4-1.8-0.0-0.6-1.50.3-0.2-1.2-0.90.2-0.60.3-0.30.1-1.1-1.1-1.6-1.10.90.7
Water consumed over 24 hours0.20.22.30.6-0.3-0.31.5-0.2-0.1-0.1-0.30.2-0.30.20.4-0.40.2-0.1-0.1-0.8-0.0-0.40.1
Number of responses in last shaping day1.71.85.3-1.51.70.70.72.00.30.31.82.3-0.81.7-0.40.4-0.41.91.51.51.9-1.40.5