Hub : Genes

Gamt

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Gamt 0.33 0.13 0.0e+00 0.3 0.29 0.3 0.3 8.0e-28 3.2e-27 1.1e-27 9.0e-28
2 Adipose gene expression Gamt 0.47 0.18 0.0e+00 0.35 0.35 0.35 0.35 4.7e-40 6.9e-40 3.0e-40 7.5e-40
3 pVTA alternative polyA NM_012793.3 0.15 0.1 6.5e-04 0.03 0.05 0.05 0.04 1.4e-02 3.6e-03 2.4e-03 5.1e-03
4 pVTA alternative polyA XM_039078453.1 0.13 0.09 2.2e-03 0.02 0.03 0.04 0.03 3.4e-02 1.3e-02 9.3e-03 1.7e-02
5 pVTA gene expression Gamt 0.46 0.17 0.0e+00 0.36 0.35 0.37 0.36 3.3e-16 3.7e-16 3.8e-17 1.1e-16
6 NAcc gene expression Gamt 0.28 0.11 0.0e+00 0.31 0.32 0.32 0.33 6.6e-37 1.4e-38 1.4e-38 1.2e-38
7 NAcc isoform ratio NM_012793.3 0.02 0.02 4.8e-03 0.02 0.01 0 0.02 9.9e-04 1.7e-02 1.9e-01 4.5e-03
8 BLA gene expression Gamt 0.28 0.13 5.6e-17 0.24 0.31 0.3 0.29 5.2e-13 7.2e-17 1.8e-16 5.8e-16
9 LHb gene expression Gamt 0.48 0.19 1.9e-10 0.33 0.34 0.34 0.34 1.3e-08 7.7e-09 6.8e-09 8.0e-09
10 Adipose mRNA stability Gamt 0.16 0.1 3.1e-10 0.03 0.07 0.07 0.06 1.3e-04 5.4e-08 4.7e-08 2.6e-07
11 Liver gene expression Gamt 0.27 0.15 0.0e+00 0.16 0.17 0.17 0.16 1.1e-17 4.7e-18 3.3e-18 8.0e-18
12 PL gene expression Gamt 0.19 0.1 0.0e+00 0.2 0.21 0.21 0.21 4.8e-22 2.5e-22 1.4e-22 9.3e-23
13 IL gene expression Gamt 0.15 0.11 2.9e-03 0.06 0.07 0.03 0.06 1.5e-02 8.2e-03 6.4e-02 1.3e-02
14 BLA mRNA stability Gamt 0.15 0.09 6.2e-04 0.03 0.04 0.01 0.03 7.3e-03 4.8e-03 8.5e-02 1.7e-02
15 OFC gene expression Gamt 0.18 0.12 2.2e-04 0.11 0.1 0.11 0.1 1.5e-03 2.0e-03 1.6e-03 1.8e-03
16 RMTg gene expression Gamt 0.18 0.12 8.3e-04 0.08 0.07 0.1 0.08 4.6e-03 6.3e-03 1.4e-03 3.4e-03
17 Brain mRNA stability Gamt 0.12 0.07 6.4e-06 0.06 0.05 0.05 0.04 2.2e-06 2.7e-05 2.7e-05 4.5e-05
18 pVTA mRNA stability Gamt 0.14 0.11 2.2e-03 0.07 0.04 0.05 0.05 4.5e-04 5.2e-03 4.1e-03 4.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density1.32.26.2-0.9-1.1-1.61.7-1.01.0-1.00.4-0.7-2.1-2.00.80.02.5-1.10.8-2.4-2.5
Area under the delay curve1.61.72.81.61.51.3-1.31.6-1.51.2-1.61.50.81.0-1.4-1.7-0.61.31.60.20.1
BMI with tail5.517.724.14.94.74.2-4.24.8-4.84.8-4.94.93.43.5-4.9-4.9-2.64.84.11.11.3
BMI without tail3.57.39.92.83.03.2-3.13.1-3.03.0-2.72.82.92.8-2.7-2.4-2.42.71.41.92.1
Body weight1.14.46.22.42.42.3-2.22.5-2.42.4-2.42.41.81.8-2.4-2.4-1.42.31.60.80.8
Weight adjusted by age1.51.72.61.31.41.5-1.51.3-1.31.2-1.01.11.61.5-1.0-0.8-1.61.0-0.51.51.5
Bone surface3.35.913.4-1.9-2.2-2.72.8-1.92.0-2.01.2-1.7-3.2-3.21.70.73.7-2.10.3-3.5-3.5
Bone volume3.25.512.9-1.7-2.0-2.62.7-1.81.9-1.91.1-1.6-3.1-3.11.70.63.6-2.10.1-3.4-3.4
Breakpoint value in progressive ratio session2.83.16.4-2.2-2.0-1.51.4-2.12.1-1.92.4-2.2-0.7-0.82.22.50.3-2.1-1.70.40.8
Number of licking bursts0.70.82.00.90.81.0-1.00.7-0.60.6-0.50.61.21.3-0.5-0.3-1.40.60.11.31.3
Context. condit. distance diff. score0.40.50.70.50.70.8-0.80.8-0.80.8-0.50.70.70.7-0.7-0.5-0.60.60.60.50.5
Locomotion velocity, session 11.61.82.9-1.3-1.3-1.51.5-1.21.2-1.31.0-1.1-1.6-1.71.10.81.6-1.2-0.9-1.5-1.5
Locomotion distance, session 12.53.37.6-1.6-1.7-2.02.1-1.41.4-1.41.1-1.1-2.5-2.30.90.62.8-0.90.8-2.8-2.7
Locomotion velocity, session 27.18.311.0-3.2-3.2-3.33.3-3.03.0-3.02.8-2.7-3.3-3.32.62.43.1-2.5-1.0-2.6-2.6
Locomotion distance, session 25.07.011.4-2.5-2.7-3.13.2-2.62.6-2.62.1-2.3-3.4-3.22.11.73.3-2.0-0.4-3.1-3.1
Locomotion velocity, session 34.04.67.9-2.5-2.4-1.91.9-2.52.5-2.52.7-2.6-1.3-1.42.62.80.7-2.5-2.30.10.1
Locomotion distance, session 30.10.10.30.20.30.4-0.50.3-0.30.3-0.10.20.50.4-0.1-0.1-0.50.1-0.50.60.5
Stereotopy head waving bouts, day 34.95.88.0-2.8-2.8-2.62.6-2.82.7-2.72.8-2.7-2.3-2.22.62.71.8-2.5-1.1-1.3-1.2
Stereotopy head waving duration, day 35.16.08.7-2.9-2.9-2.62.5-2.92.8-2.83.0-2.8-2.1-2.02.82.91.6-2.6-1.6-0.9-0.8
Locomotion velocity, session 70.50.65.2-0.7-0.4-0.10.1-0.40.5-0.40.6-0.60.1-0.40.90.70.0-1.1-2.30.40.4
Locomotion distance, session 70.91.22.20.91.11.3-1.31.0-0.91.0-0.70.81.51.2-0.6-0.5-1.30.6-0.91.51.5
Stereotopy head waving bouts, day 70.60.71.8-0.6-0.8-0.90.9-0.60.6-0.60.5-0.5-1.2-1.10.50.21.2-0.50.5-1.3-1.3
Stereotopy head waving duration, day 71.11.42.5-1.0-1.2-1.41.4-1.01.0-1.00.8-0.9-1.6-1.50.90.61.6-1.00.1-1.6-1.6
Locomotion velocity, session 82.53.05.3-1.6-1.7-2.02.0-1.51.6-1.61.3-1.4-2.3-2.21.31.02.3-1.4-0.0-2.2-2.2
Locomotion distance, session 80.60.81.5-1.0-1.0-1.01.0-0.80.8-0.80.8-0.7-1.2-1.00.60.61.2-0.50.5-1.2-1.1
Degree of sensitization distance0.30.30.40.50.60.5-0.50.6-0.60.6-0.70.60.40.3-0.6-0.7-0.20.50.40.10.1
Degree of sensitization stereotypy0.80.81.91.10.90.6-0.51.0-1.01.0-1.21.10.10.1-1.1-1.40.20.91.2-0.8-0.8
Conditioned locomotion2.83.24.12.02.02.0-2.01.8-1.81.8-1.71.82.02.0-1.7-1.5-1.91.80.91.61.6
Cocaine response after cond. corrected8.09.012.13.03.43.5-3.53.3-3.23.3-3.03.13.33.2-2.9-2.7-3.02.91.12.42.3
Cocaine response after cond. not corrected8.79.612.93.13.43.6-3.63.4-3.33.4-3.03.23.43.3-3.0-2.7-3.23.01.12.52.5
Cocaine response before conditioning0.50.61.1-0.8-0.8-0.80.8-0.80.8-0.80.9-0.9-0.6-0.80.90.80.6-0.9-1.1-0.3-0.2
Saline control response0.10.10.20.40.30.3-0.30.3-0.30.3-0.30.30.30.4-0.3-0.3-0.30.40.40.20.2
Bone: connectivity density0.60.93.2-0.4-0.5-0.90.9-0.40.4-0.4-0.1-0.1-1.3-1.20.2-0.41.8-0.41.0-1.8-1.8
Bone: cortical apparent density0.50.71.21.11.00.7-0.70.8-0.90.9-1.11.00.60.7-1.0-1.1-0.51.01.10.10.1
Bone: cortical area0.20.30.80.60.40.1-0.10.5-0.40.5-0.70.5-0.2-0.4-0.4-0.90.60.10.3-0.8-0.8
Bone: cortical porosity1.01.11.6-1.0-1.1-1.11.1-1.01.1-1.10.9-1.0-1.2-1.21.00.81.2-1.1-0.7-1.0-1.0
Bone: cortical porosity0.90.92.3-0.7-0.8-1.01.1-0.60.7-0.80.4-0.6-1.4-1.30.60.21.5-0.7-0.0-1.5-1.5
Bone: cortical thickness0.50.81.91.11.00.7-0.61.0-1.01.0-1.31.10.30.2-1.1-1.40.10.90.9-0.5-0.5
Bone: cortical thickness0.70.81.80.90.81.0-1.00.6-0.60.6-0.40.51.21.0-0.3-0.2-1.30.4-0.91.31.3
Bone: cortical tissue density0.40.50.80.90.80.6-0.60.7-0.80.7-0.90.80.50.6-0.8-0.9-0.50.80.90.20.2
Condit. Reinf. active minus inactive responses3.23.65.9-2.4-2.2-1.91.8-2.22.2-2.22.4-2.2-1.4-1.42.22.41.0-2.1-1.5-0.3-0.3
Condit. Reinf. active-inactive response ratio1.01.12.4-1.3-1.0-0.70.6-1.21.2-1.11.4-1.3-0.2-0.31.31.6-0.3-1.2-1.60.70.7
Condit. Reinf. active responses4.65.67.7-2.8-2.7-2.62.6-2.62.6-2.72.6-2.5-2.5-2.32.42.42.1-2.3-0.9-1.6-1.6
Condit. Reinf. inactive responses2.73.35.4-1.7-1.9-2.12.1-1.71.7-1.81.5-1.6-2.3-2.11.41.22.3-1.40.2-2.1-2.1
Incentive salience index mean2.93.55.1-2.3-2.2-2.12.1-2.02.0-2.12.1-2.0-1.9-1.81.91.91.7-1.8-0.6-1.3-1.3
Condit. Reinf. lever presses1.82.46.3-1.1-1.3-1.71.8-1.11.1-1.10.7-0.8-2.2-1.90.70.32.4-0.81.3-2.5-2.5
Condit. Reinf. active minus inactive responses0.91.13.7-0.6-0.8-0.60.5-1.11.1-1.11.2-1.30.0-0.11.41.5-0.6-1.3-1.91.00.9
Condit. Reinf. active-inactive response ratio0.50.51.80.80.50.7-0.70.3-0.30.2-0.20.20.91.0-0.20.1-1.30.4-0.41.31.2
Condit. Reinf. active responses1.11.55.7-0.8-1.1-0.80.8-1.31.3-1.31.4-1.5-0.4-0.51.61.6-0.1-1.7-2.40.60.5
Condit. Reinf. inactive responses0.81.04.6-0.8-0.9-0.70.7-1.01.0-0.91.1-1.1-0.4-0.81.31.10.3-1.5-2.10.10.1
Condit. Reinf. lever presses1.01.44.8-1.0-1.1-0.70.6-1.21.3-1.21.5-1.4-0.1-0.31.51.7-0.3-1.4-2.20.90.9
Condit. Reinf. lever reinforcers received0.71.05.6-0.4-0.6-0.40.3-0.90.9-0.91.0-1.10.1-0.11.31.3-0.6-1.3-2.41.00.9
Conditioned reinforcement - actives1.61.62.6-1.5-1.4-1.21.1-1.41.4-1.31.5-1.5-0.9-1.01.51.50.7-1.5-1.6-0.1-0.2
Conditioned reinforcement - inactives0.80.91.20.81.01.1-1.11.0-1.01.1-0.81.01.01.0-1.0-0.8-1.01.00.50.90.6
Conditioned locomotion4.95.99.0-2.9-2.7-2.32.3-2.82.8-2.73.0-2.9-1.7-1.82.93.01.2-2.8-2.6-0.2-0.3
Patch foraging indifference point 0 sec0.10.10.30.30.30.1-0.10.3-0.30.3-0.40.3-0.10.0-0.2-0.50.20.20.5-0.4-0.4
Patch foraging indifference point AUC0.50.51.4-0.8-0.8-0.60.6-0.80.9-0.80.9-0.9-0.4-0.50.81.00.2-0.7-1.20.00.2
Delay disc. indifference point, 0s delay3.03.312.01.71.40.7-0.61.8-1.71.5-2.22.0-0.4-0.0-2.1-2.61.12.03.5-1.9-2.0
Delay disc. indifference point, 16s delay0.10.10.40.30.30.3-0.30.3-0.20.3-0.30.30.20.3-0.3-0.3-0.20.30.60.10.0
Delay disc. indifference point, 2s delay3.13.46.62.22.01.6-1.52.1-2.22.0-2.42.30.91.0-2.2-2.6-0.22.02.5-0.6-0.4
Delay disc. indifference point, 24s delay1.00.91.61.01.11.1-1.11.1-1.11.2-1.11.01.00.9-0.9-1.0-0.80.90.20.50.6
Delay disc. indifference point, 4s delay0.50.52.80.80.70.5-0.50.8-0.70.6-0.90.80.20.4-0.7-1.00.00.61.7-0.2-0.4
Delay disc. indifference point, 8s delay1.61.72.61.61.51.6-1.51.6-1.41.0-1.41.41.31.3-1.2-1.3-1.21.20.61.00.8
Indifference point function ln k0.30.50.70.70.80.8-0.80.8-0.80.8-0.70.70.80.8-0.5-0.7-0.70.40.30.60.4
Indifference point function log k0.30.50.70.70.80.8-0.80.8-0.80.8-0.70.70.80.8-0.5-0.7-0.70.40.30.60.4
Patch foraging total patch changes 0 sec0.00.10.30.30.30.2-0.20.3-0.30.3-0.40.30.10.1-0.2-0.40.00.20.5-0.2-0.2
Patch foraging total patch changes 12 sec0.60.81.20.81.01.0-1.00.9-0.90.9-0.80.91.01.1-1.0-0.7-0.91.10.60.71.0
Patch foraging total patch changes 18 sec0.81.01.5-1.2-1.1-1.00.9-1.21.2-1.21.2-1.2-0.7-0.71.21.20.5-1.1-1.0-0.2-0.0
Patch foraging total patch changes 24 sec0.10.10.2-0.3-0.4-0.40.4-0.40.4-0.40.3-0.4-0.4-0.30.30.30.3-0.3-0.0-0.3-0.2
Patch foraging total patch changes 6 sec0.30.40.6-0.6-0.7-0.70.7-0.70.7-0.70.6-0.7-0.7-0.60.70.60.5-0.7-0.5-0.5-0.4
Patch foraging time to switch 0 sec0.81.36.10.1-0.0-0.50.50.3-0.30.3-0.60.6-1.1-0.9-0.9-1.01.60.82.5-2.0-2.0
Patch foraging water rate 0 sec1.42.25.71.21.31.7-1.71.1-1.01.1-0.70.82.11.9-0.5-0.3-2.30.5-1.22.32.4
Patch foraging water rate 12 sec3.14.87.22.32.42.5-2.62.1-2.22.2-1.91.92.72.6-1.8-1.5-2.71.80.22.32.3
Patch foraging water rate 18 sec2.93.911.11.41.62.1-2.21.2-1.21.2-0.70.92.82.7-0.7-0.1-3.21.0-0.93.33.3
Patch foraging water rate 24 sec3.95.411.22.02.22.7-2.81.9-1.92.0-1.51.73.13.0-1.5-0.9-3.31.7-0.43.23.3
Patch foraging water rate 6 sec1.01.45.10.60.71.2-1.20.5-0.40.5-0.10.21.71.5-0.00.3-2.00.1-1.52.22.2
Seeking ratio, delayed vs. immediate footshock4.04.66.5-2.4-2.4-2.22.2-2.42.4-2.42.4-2.5-1.8-1.92.52.31.4-2.5-1.8-0.8-0.8
Distance traveled before self-admin0.20.20.50.60.40.2-0.10.5-0.50.4-0.60.5-0.2-0.1-0.5-0.70.30.40.6-0.6-0.7
Distance traveled after self-admin0.60.70.9-0.9-0.9-0.90.9-0.90.8-0.80.9-0.9-0.8-0.90.90.80.8-0.9-0.6-0.6-0.5
Extensor digitorum longus weight4.818.924.34.84.94.7-4.64.9-4.94.9-4.84.94.04.1-4.8-4.6-3.34.73.42.22.1
Bone: elastic displacement0.30.30.5-0.4-0.5-0.60.6-0.60.6-0.60.5-0.6-0.5-0.60.60.50.3-0.7-0.7-0.3-0.3
Bone: elastic work0.10.10.30.60.50.3-0.30.5-0.40.4-0.60.40.1-0.1-0.2-0.6-0.10.0-0.4-0.2-0.2
Bone: endosteal estimation0.10.10.40.50.40.3-0.20.4-0.40.4-0.50.40.10.1-0.4-0.6-0.00.30.6-0.3-0.3
Bone: endosteal perimeter0.40.91.4-1.0-1.0-1.01.0-0.91.0-0.90.9-0.9-1.0-1.11.00.71.0-1.2-0.7-0.8-0.8
Epididymis fat weight0.10.20.7-0.7-0.6-0.40.3-0.60.6-0.60.8-0.6-0.10.10.40.8-0.1-0.10.30.40.5
Delta time in closed arm before/after self-admin3.93.86.71.81.92.3-2.31.8-1.81.7-1.41.62.52.5-1.5-1.0-2.61.70.12.42.3
Delta time in open arm before/after self-admin0.50.51.10.80.70.5-0.40.8-0.70.7-0.90.90.10.1-0.8-1.00.10.90.7-0.4-0.5
Diff in mean of infusions in LGA sessions1.31.52.5-1.5-1.4-1.21.2-1.51.4-1.41.6-1.5-0.8-0.81.41.60.6-1.4-0.6-0.20.0
Delay discount exponential model param1.61.72.6-1.6-1.5-1.31.3-1.61.5-1.21.6-1.5-0.9-1.01.41.60.7-1.3-1.4-0.3-0.2
Extinction: sum of active levers before priming0.40.41.3-0.7-0.5-0.10.1-0.60.6-0.40.9-0.70.30.30.61.0-0.4-0.5-0.60.71.1
Active lever presses in extinction session 62.12.03.0-1.7-1.6-1.51.4-1.61.6-1.51.7-1.7-1.2-1.21.71.71.0-1.7-1.1-0.6-0.4
Bone: final force0.50.92.31.31.10.8-0.71.2-1.01.1-1.41.20.30.1-1.0-1.50.10.80.6-0.5-0.5
Bone: final moment0.40.71.81.11.00.7-0.61.0-0.90.9-1.21.00.20.1-0.8-1.30.10.60.4-0.5-0.5
Food consumed during 24 hour testing period0.70.81.11.11.01.0-1.01.0-1.01.0-1.01.00.91.0-0.8-0.9-0.80.80.90.50.6
Glucose1.31.93.01.71.61.5-1.51.6-1.61.6-1.71.61.21.2-1.5-1.6-0.91.50.90.40.5
Heart weight0.10.20.8-0.2-0.10.2-0.2-0.10.2-0.20.4-0.30.40.40.30.5-0.6-0.2-0.90.90.8
Delay discount hyperbolic model param2.12.23.6-1.8-1.7-1.51.5-1.81.7-1.51.8-1.8-1.0-1.11.61.90.7-1.5-1.6-0.2-0.1
Intermittent access intake day 1-15 change3.93.96.8-2.3-2.1-1.71.6-2.22.2-2.22.5-2.4-1.1-1.22.42.60.6-2.4-2.40.20.3
Intermittent access intake escalation2.72.76.0-1.9-1.6-1.00.9-1.81.8-1.82.2-2.0-0.3-0.42.02.4-0.2-1.9-2.41.11.1
Intermittent access intake escalation 23.53.59.6-2.1-1.8-1.21.1-2.02.0-2.02.4-2.2-0.3-0.62.32.7-0.2-2.1-3.11.01.3
Intermitt. access day 1 inactive lever presses0.30.31.20.10.30.6-0.60.3-0.20.20.00.10.80.60.00.2-0.8-0.0-0.81.11.0
Intermitt. access day 15 inactive lever presses0.20.20.8-0.6-0.5-0.30.3-0.50.5-0.50.7-0.5-0.1-0.10.60.7-0.1-0.5-0.90.40.2
Intermitt. access escalation Index0.40.31.40.0-0.2-0.50.5-0.10.1-0.1-0.2-0.1-0.8-0.80.1-0.30.9-0.30.4-1.1-1.2
Intermittent access day 1 total infusions0.00.00.10.00.10.1-0.10.2-0.20.2-0.20.20.00.0-0.2-0.20.10.10.3-0.0-0.1
Intermittent access day 15 total infusions0.91.02.2-1.2-1.0-0.60.6-1.01.1-1.01.3-1.2-0.2-0.31.21.5-0.1-1.2-1.50.70.6
Intermittent access terminal intake (last 3 days)0.60.61.6-1.1-0.8-0.50.5-0.80.8-0.81.0-0.9-0.3-0.51.01.10.2-1.0-1.30.30.2
Intermittent access total infusions0.10.10.2-0.4-0.2-0.10.1-0.20.2-0.20.4-0.30.10.00.30.4-0.1-0.3-0.40.40.2
Intermittent access day 1 locomotion0.20.20.4-0.6-0.5-0.40.4-0.50.5-0.50.6-0.5-0.2-0.20.50.70.0-0.5-0.50.30.0
Intermittent access day 15 total locomotion2.32.44.2-2.0-1.8-1.51.5-1.81.8-1.82.0-1.9-1.1-1.11.82.10.6-1.6-1.40.1-0.1
Intermittent access total locomotion0.70.81.3-1.2-1.0-0.90.9-1.01.0-1.01.1-1.0-0.8-0.81.01.10.6-1.0-0.7-0.1-0.4
Intermittent access standard deviation1.31.34.7-1.2-1.1-0.70.7-1.21.2-1.21.5-1.3-0.3-0.51.31.6-0.2-1.3-2.20.70.6
Left kidney weight0.20.41.0-0.5-0.6-0.70.7-0.50.6-0.50.4-0.5-0.9-1.00.50.20.9-0.6-0.7-1.0-0.8
Right kidney weight1.13.25.8-1.9-1.9-1.71.7-1.92.0-2.02.0-2.0-1.4-1.62.12.01.0-2.1-2.4-0.5-0.3
Cocaine induced anxiety1.61.93.1-1.3-1.4-1.61.6-1.31.3-1.31.0-1.2-1.7-1.71.10.91.7-1.2-0.9-1.6-1.6
Post-drug Anxiety1.51.72.8-1.3-1.3-1.51.5-1.21.3-1.31.0-1.1-1.6-1.71.00.81.6-1.0-0.7-1.5-1.5
Baseline Anxiety0.20.21.10.00.10.3-0.4-0.0-0.00.00.2-0.00.60.60.00.3-0.90.1-0.41.01.0
Tail length1.75.19.6-2.8-2.5-1.81.7-2.42.6-2.52.9-2.7-1.0-1.32.83.10.7-2.7-3.10.50.6
Length with tail1.65.88.5-2.7-2.6-2.32.3-2.62.7-2.72.7-2.7-1.9-2.22.82.71.6-2.9-2.9-0.8-0.7
Length without tail0.51.22.3-0.8-1.0-1.31.3-1.00.9-0.90.6-0.8-1.5-1.50.80.41.4-0.9-0.2-1.5-1.5
Times rat made contact with spout0.70.81.50.90.91.0-1.00.9-0.90.8-0.70.81.11.1-0.7-0.6-1.20.80.41.10.8
Lifetime Intake0.00.00.1-0.3-0.2-0.10.1-0.10.2-0.10.3-0.2-0.0-0.00.20.3-0.0-0.2-0.20.20.0
Liver weight, left2.23.56.02.02.01.8-1.82.0-2.02.0-2.02.11.51.7-2.2-2.0-1.22.32.50.60.7
Liver weight, right1.01.74.01.41.31.0-1.01.4-1.41.4-1.51.60.60.8-1.7-1.6-0.31.82.0-0.3-0.3
Locomotor activity4.16.48.4-2.7-2.7-2.72.7-2.72.8-2.72.5-2.7-2.5-2.72.82.32.4-2.9-2.0-1.7-1.6
Locomotor testing distance2.13.54.7-2.0-2.0-2.01.9-2.02.1-2.11.9-2.1-1.7-1.82.11.81.7-2.2-1.6-1.1-1.0
Locomotor testing rearing0.20.30.90.30.40.5-0.60.3-0.20.3-0.10.20.70.6-0.00.0-0.80.1-0.70.91.0
Locomotion in novel chamber0.10.10.4-0.0-0.1-0.10.1-0.20.2-0.30.2-0.30.00.10.30.4-0.4-0.1-0.60.30.3
Locomotion in novel chamber post-restriction0.40.51.0-0.6-0.6-0.30.3-0.70.7-0.80.9-0.8-0.0-0.01.01.0-0.3-0.9-0.90.50.7
Fecal boli incidents, locomotor time 11.51.63.01.61.51.3-1.21.5-1.31.3-1.51.50.90.9-1.7-1.5-0.81.70.50.50.1
Change in fecal boli incidents, locomotor task0.20.21.0-0.4-0.3-0.30.3-0.30.2-0.20.3-0.5-0.3-0.40.70.30.5-1.0-0.8-0.4-0.2
Time >=10cm from walls, locomotor time 10.40.41.60.30.2-0.10.20.4-0.20.4-0.60.3-0.6-0.8-0.3-0.71.00.1-0.2-1.2-1.2
Bouts of movement, locomotor time 10.10.10.3-0.2-0.2-0.00.0-0.20.2-0.10.3-0.30.1-0.00.30.4-0.1-0.3-0.60.30.3
Total resting periods, locomotor time 10.10.10.3-0.4-0.4-0.30.3-0.40.4-0.30.5-0.4-0.1-0.30.50.50.1-0.5-0.50.20.1
Rest time, locomotor task time 10.30.40.6-0.7-0.7-0.70.7-0.70.7-0.50.7-0.6-0.6-0.60.50.60.7-0.5-0.0-0.4-0.5
Distance moved, locomotor task time 10.30.31.10.40.30.00.00.4-0.50.4-0.60.4-0.4-0.4-0.3-0.80.80.10.5-1.0-0.9
Vertical activity count, locomotor time 10.70.71.20.91.01.1-1.11.0-0.80.8-0.80.71.00.9-0.4-0.6-1.00.3-0.61.01.0
Time >=10cm from walls, locomotor time 21.71.82.91.71.61.6-1.61.7-1.51.5-1.61.51.31.1-1.3-1.4-1.01.2-0.10.70.7
Bouts of movement, locomotor time 21.61.72.5-1.3-1.4-1.51.5-1.31.3-1.41.1-1.1-1.6-1.61.00.91.5-1.0-0.3-1.4-1.3
Total resting periods, locomotor time 21.61.72.6-1.3-1.4-1.51.5-1.31.3-1.41.0-1.1-1.6-1.61.00.81.6-1.0-0.2-1.5-1.4
Rest time, locomotor task time 20.91.11.4-1.1-1.1-1.21.2-1.11.1-1.01.0-1.0-1.1-1.21.00.91.1-1.0-0.6-0.9-0.9
Distance moved, locomotor task time 20.91.11.41.11.11.2-1.11.2-1.21.2-1.11.11.01.1-1.1-1.0-0.91.10.90.60.6
Vertical activity count, locomotor time 21.81.92.81.41.51.7-1.71.5-1.41.4-1.21.31.61.6-1.2-1.0-1.61.30.41.41.2
Light reinforcement 15.810.514.6-3.8-3.7-3.43.4-3.73.7-3.73.7-3.7-2.9-2.93.53.62.4-3.4-2.4-1.4-1.3
Light reinforcement 22.33.14.2-2.0-2.0-1.91.9-2.01.9-2.01.9-1.9-1.6-1.71.91.81.4-1.8-1.5-0.8-0.9
Bone: marrow area0.10.20.40.50.40.3-0.30.5-0.40.4-0.50.50.10.1-0.4-0.6-0.00.30.6-0.3-0.3
Bone: maximum diameter1.32.33.2-1.5-1.6-1.71.7-1.51.6-1.51.4-1.5-1.7-1.81.61.21.7-1.7-1.0-1.3-1.3
Bone: maximum force0.71.12.51.41.31.1-1.01.4-1.21.3-1.51.30.60.4-1.1-1.6-0.30.90.4-0.1-0.2
Bone: maximum moment0.50.92.01.31.10.9-0.91.2-1.11.1-1.31.10.50.3-1.0-1.4-0.30.80.3-0.2-0.2
Mean time between licks in bursts2.43.46.0-2.0-2.0-1.61.6-2.22.2-2.22.3-2.3-1.0-1.12.22.50.5-2.1-2.20.20.3
Mean num. licks in bursts0.00.00.2-0.2-0.1-0.10.10.0-0.10.1-0.00.1-0.2-0.3-0.1-0.10.3-0.0-0.1-0.3-0.4
Cd content in liver0.10.10.50.70.40.2-0.20.3-0.30.3-0.60.40.0-0.0-0.3-0.60.00.3-0.0-0.2-0.2
Co content in liver0.30.30.6-0.5-0.6-0.50.5-0.70.7-0.70.7-0.7-0.3-0.30.70.80.1-0.6-0.70.20.2
Cu content in liver0.30.41.5-0.1-0.3-0.60.6-0.20.2-0.2-0.1-0.1-0.9-1.00.1-0.31.1-0.20.2-1.2-1.2
Fe content in liver0.10.10.30.10.10.3-0.30.1-0.10.10.10.00.40.3-0.10.2-0.40.1-0.20.50.5
K content in liver0.80.82.2-0.5-0.7-1.01.0-0.60.6-0.60.3-0.4-1.3-1.20.40.01.5-0.40.6-1.5-1.5
Mg content in liver0.80.82.3-0.4-0.7-1.01.0-0.60.6-0.60.2-0.4-1.3-1.20.4-0.01.5-0.50.5-1.5-1.5
Mn content in liver3.74.27.3-2.0-2.0-2.32.3-1.91.9-1.91.5-1.7-2.5-2.61.71.12.7-2.0-0.6-2.4-2.4
Na content in liver0.50.62.00.30.2-0.20.30.3-0.30.3-0.60.5-0.7-0.5-0.6-0.91.10.51.4-1.3-1.3
Rb content in liver0.40.51.90.1-0.1-0.50.50.00.0-0.0-0.30.1-0.9-0.9-0.2-0.61.20.00.6-1.4-1.4
Se content in liver0.30.30.5-0.7-0.7-0.60.6-0.60.6-0.60.7-0.5-0.5-0.50.50.60.6-0.50.0-0.4-0.4
Sr content in liver0.50.41.40.40.50.7-0.80.4-0.40.4-0.20.30.90.9-0.3-0.0-1.10.4-0.41.21.2
Zn content in liver0.80.93.1-0.5-0.30.2-0.2-0.60.5-0.50.9-0.70.80.80.71.2-1.3-0.5-1.21.81.8
Bone: minimum diameter0.10.10.3-0.1-0.2-0.30.3-0.10.2-0.10.0-0.1-0.4-0.50.3-0.10.5-0.40.1-0.6-0.6
Time in familiar zone, hab. session 11.11.02.2-1.2-1.0-0.60.5-1.11.1-1.11.3-1.2-0.1-0.21.31.5-0.2-1.2-1.40.80.8
Time in novel zone, hab. session 10.40.41.10.70.50.2-0.10.7-0.60.6-0.80.7-0.3-0.4-0.6-1.00.60.40.4-1.1-1.1
Total zone transitions, hab. session 12.73.85.9-2.0-2.0-2.32.3-1.91.9-1.91.6-1.7-2.4-2.31.61.32.3-1.6-0.4-2.2-2.2
Total locomotion distance, hab. session 13.95.59.1-2.3-2.4-2.72.7-2.22.2-2.21.8-2.0-3.0-3.01.91.43.0-2.0-0.5-2.8-2.8
Locomotion velocity, hab. session 14.26.09.2-2.5-2.6-2.92.9-2.42.4-2.42.1-2.2-3.0-2.92.01.73.0-2.0-0.4-2.7-2.7
Time in familiar zone, hab. session 23.03.16.9-2.1-1.9-1.21.2-2.02.0-1.92.4-2.2-0.4-0.52.22.6-0.1-2.0-2.21.11.1
Time in novel zone, hab. session 22.22.25.01.81.61.1-1.01.7-1.71.7-2.11.80.40.3-1.8-2.20.11.61.6-0.9-0.9
Total zone transitions, hab. session 22.12.78.9-1.0-1.2-1.81.8-0.90.9-1.00.4-0.6-2.4-2.20.3-0.12.6-0.31.2-3.0-3.0
Total locomotion distance, hab. session 23.24.26.7-2.1-2.2-2.42.4-2.02.0-2.01.7-1.7-2.6-2.41.51.42.5-1.40.0-2.4-2.3
Locomotion velocity, hab. session 24.05.49.1-2.3-2.4-2.72.8-2.22.2-2.21.8-1.9-3.0-2.81.61.43.0-1.50.2-2.9-2.9
Novel to familiar place preference ratio1.81.94.41.51.30.8-0.71.6-1.51.5-1.81.6-0.00.0-1.6-2.10.61.41.7-1.3-1.3
Novelty place preference1.11.12.51.00.90.5-0.41.1-1.11.1-1.31.2-0.2-0.2-1.2-1.60.71.01.3-1.3-1.3
Time in novel zone, NPP test1.21.33.01.21.10.7-0.61.3-1.31.3-1.51.40.0-0.0-1.3-1.70.51.11.3-1.1-1.1
Total zone transitions, NPP test1.31.85.0-1.0-1.1-1.51.6-1.00.9-1.00.6-0.7-1.9-1.70.40.22.0-0.31.0-2.2-2.2
Total locomotion distance, NPP test1.21.64.8-0.9-1.0-1.41.4-0.80.8-0.80.5-0.5-1.8-1.70.30.12.0-0.30.7-2.2-2.2
Locomotion velocity, NPP test1.42.05.0-1.2-1.3-1.61.7-1.11.0-1.10.8-0.8-2.0-1.90.60.42.1-0.60.5-2.2-2.2
Intraocular pressure1.01.44.00.70.91.2-1.30.7-0.70.7-0.40.51.61.6-0.5-0.1-1.90.7-0.52.02.0
Delta distance traveled before/after self-admin1.31.42.1-1.4-1.3-1.21.1-1.41.3-1.31.4-1.4-0.8-1.01.41.50.7-1.4-1.3-0.2-0.1
Delta ambulatory time before/after self-admin1.61.82.5-1.5-1.5-1.41.4-1.61.4-1.51.6-1.5-1.1-1.21.51.50.9-1.5-1.1-0.4-0.4
Parametrial fat weight0.20.31.5-0.5-0.4-0.10.1-0.40.5-0.40.7-0.60.1-0.00.70.8-0.2-0.7-1.20.50.6
Pavlov. Cond. lever latency0.70.82.30.80.70.9-1.00.5-0.50.5-0.40.41.21.1-0.3-0.1-1.50.4-1.01.51.5
Pavlov. Cond. magazine entry latency2.02.64.9-2.2-2.0-1.51.5-1.91.9-1.92.2-1.9-1.1-1.01.82.20.8-1.7-0.9-0.1-0.1
Pavlov. Cond. change in total contacts0.20.20.4-0.7-0.5-0.40.4-0.40.4-0.40.5-0.3-0.5-0.40.30.40.5-0.30.5-0.4-0.4
Pavlov. Cond. index score0.91.22.1-1.4-1.3-1.21.2-1.11.1-1.11.1-1.0-1.2-1.10.90.91.3-0.90.5-1.0-1.0
Pavlov. Cond. latency score1.31.72.9-1.6-1.4-1.41.5-1.21.2-1.21.2-1.1-1.6-1.41.00.91.7-1.10.6-1.4-1.4
Pavlov. Cond. lever contacts1.11.33.2-1.0-1.0-1.31.3-0.80.8-0.80.7-0.7-1.6-1.40.60.41.8-0.71.0-1.8-1.8
Pavlov. Cond. magazine entry number0.60.81.81.41.10.9-0.81.0-1.01.1-1.21.00.70.6-0.9-1.1-0.60.80.10.30.3
Pavlov. Cond. intertrial magazine entries0.20.31.00.20.20.4-0.40.0-0.10.00.1-0.00.60.70.00.2-0.90.1-0.61.01.0
Pavlov. Cond. lever-magazine prob. diff.1.21.52.7-1.6-1.5-1.31.3-1.31.3-1.31.4-1.2-1.3-1.21.21.21.3-1.10.2-0.9-0.9
Pavlov. Cond. response bias1.01.22.4-1.5-1.4-1.11.1-1.31.3-1.31.4-1.3-0.9-0.91.21.40.8-1.1-0.3-0.4-0.4
Pavlov. Cond. lever latency0.60.86.40.50.50.4-0.30.6-0.70.7-0.70.80.10.6-1.1-0.8-0.01.22.5-0.3-0.4
Pavlov. Cond. magazine entry latency0.30.42.1-0.7-0.5-0.30.3-0.50.5-0.50.6-0.6-0.2-0.40.70.70.2-0.8-1.50.10.2
Pavlov. Cond. change in total contacts0.40.64.4-0.4-0.5-0.30.3-0.60.7-0.70.7-0.8-0.0-0.31.00.8-0.2-1.0-2.10.50.5
Pavlov. Cond. index score0.60.75.6-0.6-0.5-0.30.3-0.60.7-0.60.8-0.8-0.0-0.41.00.9-0.1-1.1-2.40.40.5
Pavlov. Cond. latency score0.60.75.3-0.6-0.6-0.40.4-0.70.8-0.70.8-0.9-0.2-0.61.10.90.2-1.2-2.30.20.3
Pavlov. Cond. lever contacts0.40.65.5-0.3-0.3-0.10.0-0.40.5-0.50.6-0.70.3-0.10.90.8-0.4-0.9-2.30.80.8
Pavlov. Cond. magazine entry number0.50.62.90.80.70.5-0.50.7-0.80.7-0.90.90.30.6-1.0-0.9-0.21.11.7-0.1-0.3
Pavlov. Cond. intertrial magazine entries0.70.91.51.21.01.0-1.10.9-1.01.0-0.80.91.11.1-0.9-0.7-1.20.90.41.00.9
Pavlov. Cond. lever-magazine prob. diff.0.60.85.3-0.7-0.7-0.50.4-0.70.8-0.70.8-0.9-0.2-0.61.10.90.1-1.2-2.30.20.3
Pavlov. Cond. response bias0.91.38.1-0.8-0.8-0.50.4-0.91.0-0.91.2-1.20.0-0.41.41.4-0.3-1.4-2.90.80.9
Time in closed arm before self-admin0.60.72.70.1-0.1-0.50.60.1-0.00.0-0.40.3-1.0-0.9-0.4-0.71.30.31.2-1.6-1.7
Time in closed arm after self-admin0.00.00.1-0.00.00.1-0.1-0.00.0-0.00.1-0.00.10.20.00.1-0.2-0.0-0.10.20.2
Time in open arm before self-admin0.30.30.7-0.6-0.5-0.30.3-0.60.5-0.50.7-0.70.0-0.00.70.8-0.1-0.8-0.70.40.5
Time in open arm after self-admin0.60.71.01.01.00.9-0.91.0-0.90.9-1.01.00.70.7-0.9-1.0-0.50.90.70.30.3
Bone: periosteal estimation0.10.20.90.40.2-0.10.10.3-0.20.3-0.50.4-0.4-0.5-0.2-0.70.70.00.5-0.9-0.9
Bone: periosteal perimeter0.40.61.4-0.6-0.7-0.80.8-0.60.7-0.60.4-0.6-1.0-1.10.80.31.2-1.0-0.5-1.0-1.0
Bone: post-yield work0.60.81.11.01.01.0-1.01.0-1.01.0-1.01.00.90.8-0.9-0.9-0.80.90.40.60.6
Progressive ratio test 1 active lever presses0.30.30.60.40.50.6-0.60.5-0.50.5-0.30.50.70.7-0.4-0.3-0.80.50.20.80.5
Progressive ratio test 1 breakpoint0.30.30.60.50.60.6-0.60.6-0.60.6-0.40.60.70.7-0.5-0.4-0.80.60.40.70.4
Progressive ratio test 1 inactive lever presses0.00.00.1-0.3-0.2-0.20.2-0.20.2-0.10.2-0.1-0.2-0.10.10.20.1-0.10.00.1-0.3
Progressive ratio test 2 active lever presses0.20.20.8-0.00.10.3-0.40.1-0.10.10.2-0.00.60.50.00.3-0.7-0.0-0.50.90.7
Progressive ratio test 2 breakpoint0.10.10.2-0.3-0.2-0.00.0-0.20.2-0.20.4-0.30.10.00.30.4-0.2-0.3-0.50.50.3
Progressive ratio test 2 inactive lever presses0.10.10.2-0.5-0.3-0.30.3-0.20.3-0.20.3-0.2-0.3-0.30.10.20.4-0.20.1-0.2-0.4
Incentive Sensitization - Responses0.20.20.80.00.20.4-0.50.2-0.10.20.10.00.60.6-0.00.2-0.60.0-0.40.80.9
Incentive Sensitization - Breakpoint0.10.10.6-0.10.10.3-0.30.0-0.00.10.2-0.10.50.40.10.3-0.5-0.1-0.40.70.7
Sum of active levers in priming session hrs 5-60.00.00.1-0.1-0.1-0.10.1-0.1-0.00.00.0-0.0-0.1-0.1-0.00.00.20.00.3-0.2-0.2
Progressive ratio0.30.32.50.30.40.4-0.40.4-0.40.3-0.40.50.30.5-0.7-0.4-0.40.91.60.20.2
Food seeking constrained by brief footshock0.60.71.4-1.0-1.0-0.90.9-0.90.8-0.80.9-0.6-0.9-0.70.40.71.0-0.21.2-0.8-0.7
Seeking ratio, punishment vs. effort0.40.50.8-0.7-0.8-0.80.8-0.70.8-0.70.7-0.7-0.8-0.90.70.60.9-0.7-0.5-0.7-0.6
Retroperitoneal fat weight0.30.91.60.91.01.0-1.01.1-1.01.0-0.91.10.91.0-1.1-0.9-0.81.21.30.50.5
Reaction time number correct2.13.05.11.81.82.0-2.01.6-1.71.7-1.31.52.22.2-1.3-1.0-2.31.30.32.12.1
Reaction time mean minus median0.40.53.3-0.6-0.5-0.30.2-0.60.7-0.60.7-0.70.0-0.30.80.8-0.2-0.8-1.80.50.5
Reaction time mean minus median AUC0.20.30.7-0.4-0.4-0.50.5-0.30.4-0.40.2-0.3-0.7-0.80.40.00.8-0.5-0.6-0.8-0.8
Reaction time num false alarms1.01.42.80.91.21.4-1.51.1-1.01.1-0.80.81.61.4-0.5-0.5-1.50.4-0.61.71.7
Reaction time num false alarms AUC1.41.93.61.11.41.7-1.71.3-1.21.3-0.91.01.91.7-0.8-0.6-1.80.7-0.41.91.9
Reaction time trials correct on left2.13.05.11.81.82.0-2.01.6-1.71.7-1.31.52.22.2-1.3-1.0-2.31.30.32.12.1
Reaction time trials on left2.02.94.71.81.82.0-2.01.6-1.61.6-1.31.42.12.1-1.3-1.0-2.21.30.32.02.0
Reaction time mean0.10.11.00.1-0.0-0.20.2-0.10.1-0.1-0.1-0.1-0.3-0.50.2-0.10.3-0.3-1.0-0.4-0.5
Reaction time mean AUC0.10.11.00.10.0-0.20.2-0.00.1-0.0-0.2-0.0-0.3-0.50.1-0.20.3-0.2-1.0-0.5-0.5
Median of all reaction times0.10.10.40.40.30.00.00.3-0.30.3-0.50.3-0.2-0.3-0.3-0.60.30.1-0.2-0.6-0.6
Reaction time omissions0.40.50.8-0.6-0.8-0.90.9-0.80.8-0.80.6-0.8-0.8-0.90.70.60.6-0.7-0.7-0.6-0.6
Reaction time false alarm rate0.10.10.20.10.40.4-0.40.4-0.30.4-0.30.30.50.3-0.1-0.2-0.30.0-0.30.40.4
Reaction time premature initiation rate0.50.61.8-0.7-0.7-0.40.4-0.80.8-0.81.0-0.90.0-0.10.91.1-0.4-0.8-1.30.70.7
Reaction time premature initiations0.60.93.50.20.20.6-0.7-0.00.0-0.00.3-0.21.21.10.30.7-1.6-0.2-1.31.81.9
Std. dev. reaction times0.20.33.1-0.2-0.3-0.20.2-0.30.5-0.40.3-0.4-0.2-0.50.60.4-0.0-0.6-1.80.10.0
Reaction time trials completed2.02.94.71.81.82.0-2.01.6-1.61.6-1.31.42.12.1-1.3-1.0-2.21.30.32.02.0
Reaction time trials AUC2.33.35.91.91.92.1-2.11.7-1.71.7-1.31.52.42.3-1.3-1.0-2.41.40.22.32.2
Run reversals in cocaine runway, females0.40.40.7-0.8-0.7-0.70.7-0.80.7-0.70.7-0.7-0.6-0.60.70.70.5-0.70.4-0.3-0.3
Run reversals in cocaine runway, males1.61.62.2-1.5-1.5-1.41.4-1.51.4-1.51.4-1.4-1.2-1.11.31.30.9-1.3-0.0-0.6-0.7
Latency to leave start box in cocaine runway1.92.03.1-1.1-1.4-1.61.6-1.31.3-1.41.0-1.3-1.7-1.71.40.91.7-1.5-0.9-1.6-1.6
Latency to leave start box in cocaine runway, F1.31.44.6-0.3-0.7-1.21.3-0.60.6-0.70.1-0.5-1.7-1.70.5-0.11.9-0.70.1-2.1-2.1
Latency to leave start box in cocaine runway, M1.11.13.2-1.0-0.9-0.50.4-1.01.1-1.01.3-1.20.10.01.31.6-0.5-1.2-1.81.01.0
Std. dev. time between licks in bursts0.81.02.6-0.7-0.9-0.90.9-1.01.0-1.00.9-1.1-0.8-1.01.30.90.8-1.4-1.6-0.5-0.3
Total sessions with >9 infusions0.10.10.3-0.1-0.1-0.20.20.00.00.0-0.1-0.0-0.3-0.30.1-0.10.5-0.2-0.2-0.4-0.5
Short access day 1 total inactive lever presses0.10.10.3-0.5-0.4-0.40.4-0.30.4-0.30.4-0.3-0.4-0.40.20.30.3-0.1-0.1-0.1-0.5
Short access day 10 total inactive lever presses0.10.10.20.10.20.3-0.30.2-0.20.2-0.10.10.40.2-0.1-0.0-0.30.2-0.50.30.4
Short access day 1 total infusions0.70.71.3-1.0-0.9-1.01.0-0.80.8-0.70.7-0.7-1.1-1.10.60.51.1-0.7-0.4-0.8-1.1
Short access day 10 total infusions0.10.10.60.00.10.2-0.20.1-0.10.20.10.10.40.4-0.10.1-0.60.1-0.20.70.3
Short access total infusions0.00.00.1-0.2-0.1-0.10.1-0.00.10.00.1-0.0-0.2-0.20.00.00.2-0.1-0.1-0.1-0.3
Short access day 1 locomotion1.31.41.9-1.4-1.3-1.21.2-1.21.2-1.21.2-1.2-1.1-1.31.21.11.1-1.4-1.2-0.6-0.9
Short access day 10 total locomotion2.12.45.9-1.7-1.6-1.31.2-1.71.7-1.71.9-1.9-0.8-0.91.92.10.3-1.9-2.40.40.2
Short access total locomotion0.70.71.6-1.0-0.9-0.80.8-0.90.9-0.80.9-1.0-0.6-0.81.00.90.6-1.1-1.3-0.2-0.4
One hour access (0.3 mA shock)0.20.20.30.40.50.4-0.40.5-0.50.5-0.40.50.40.4-0.5-0.4-0.40.50.50.30.0
Compulsive drug intake0.60.61.30.90.70.4-0.40.8-0.80.8-1.00.90.00.1-0.9-1.20.30.81.1-0.7-0.6
One hour access (shock baseline)0.20.21.20.10.20.3-0.40.1-0.10.20.10.10.60.50.00.3-0.90.0-0.51.10.6
Social response proportion1.51.62.4-1.1-1.4-1.51.5-1.41.4-1.41.1-1.2-1.6-1.51.11.01.3-1.0-0.6-1.2-1.2
Social responses6.68.511.1-3.1-3.2-3.02.9-3.23.3-3.33.1-3.3-2.5-2.83.33.12.1-3.3-3.2-1.2-1.0
Social time0.30.41.60.70.50.3-0.30.6-0.60.5-0.70.70.00.2-0.9-0.80.11.01.3-0.5-0.4
Soleus weight7.020.629.65.35.14.6-4.55.2-5.25.2-5.45.33.63.7-5.2-5.4-2.54.94.41.21.2
Bone: stiffness1.72.75.11.91.91.7-1.62.1-1.92.0-2.12.01.11.0-1.9-2.3-0.51.71.5-0.0-0.0
Tibialis anterior weight1.03.44.72.02.01.9-1.92.2-2.12.1-2.12.11.51.6-2.1-2.1-1.02.02.10.50.5
Time to tail flick, vehicle, before self-admin1.31.32.1-1.1-1.2-1.31.3-1.01.2-1.20.9-1.0-1.4-1.41.00.81.4-1.0-0.3-1.3-1.3
Time to tail flick, vehicle, after self-admin0.40.52.20.10.30.6-0.70.2-0.10.20.10.11.01.0-0.00.3-1.10.2-0.51.41.5
Time to tail flick, test, before self-admin1.01.01.7-0.8-0.9-1.11.2-0.90.9-0.90.7-0.8-1.3-1.30.80.51.3-1.0-0.3-1.2-1.3
Time to tail flick, test, after self-admin0.50.60.9-0.8-0.8-0.90.9-0.80.9-1.00.7-0.7-0.9-0.80.80.60.7-0.7-0.2-0.6-0.7
Delta time to tail flick, vehicle, before/after SA2.02.03.91.21.41.6-1.71.2-1.21.3-0.91.11.91.9-1.0-0.6-1.91.20.31.92.0
Delta time to tail flick, test, before/after SA0.20.20.8-0.10.00.3-0.3-0.00.0-0.10.2-0.10.50.50.00.3-0.70.1-0.50.90.8
Tibia length0.61.62.9-1.4-1.3-1.21.1-1.51.5-1.41.5-1.5-0.7-0.91.51.60.4-1.5-1.70.10.0
Ambulatory time before self-admin0.20.20.50.60.40.2-0.20.5-0.50.5-0.60.5-0.00.0-0.5-0.70.20.40.6-0.4-0.5
Ambulatory time after self-admin0.40.40.5-0.6-0.7-0.70.7-0.70.6-0.60.6-0.7-0.7-0.70.60.60.6-0.7-0.4-0.5-0.5
Bone: tissue strength0.80.81.81.01.00.7-0.71.0-1.01.0-1.31.10.30.4-1.1-1.3-0.11.11.1-0.4-0.4
Total heroin consumption1.41.72.6-1.6-1.5-1.31.3-1.61.5-1.51.6-1.6-0.9-0.91.61.60.8-1.5-0.5-0.3-0.0
Bone: trabecular number1.72.74.3-1.7-1.7-1.81.9-1.61.6-1.61.3-1.5-1.9-2.01.51.12.1-1.6-0.6-1.7-1.7
Bone: trabecular spacing3.34.28.71.92.02.3-2.41.8-1.81.8-1.41.62.72.7-1.5-0.9-2.91.70.12.72.7
Bone: trabecular thickness3.54.211.3-1.3-1.6-2.22.3-1.31.4-1.40.6-1.1-2.8-2.81.20.13.4-1.60.6-3.3-3.4
Bone: trabecular tissue density1.62.33.81.71.61.5-1.41.6-1.51.5-1.61.61.21.5-1.7-1.6-1.21.92.00.60.6
Water consumed over 24 hours0.20.30.70.70.50.2-0.10.5-0.50.5-0.70.6-0.2-0.2-0.5-0.90.40.30.5-0.7-0.8
Number of responses in last shaping day0.10.10.2-0.4-0.3-0.20.2-0.20.2-0.20.3-0.3-0.1-0.10.30.30.1-0.4-0.30.2-0.1