Hub : Genes

Gal3st1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Gal3st1 0.03 0.02 4.1e-04 0.01 0.04 0.03 0.02 1.0e-02 4.6e-05 4.4e-04 1.2e-03
2 NAcc mRNA stability Gal3st1 0.04 0.02 1.6e-06 0.06 0.05 0.06 0.02 1.2e-07 1.3e-06 4.1e-07 9.7e-04
3 Brain alternative TSS NM_001109447.1 0.07 0.04 6.7e-05 0.03 0.05 0.05 0.05 1.3e-03 2.7e-05 3.0e-05 2.0e-05
4 PL isoform ratio NM_001109447.1 0.09 0.05 2.4e-04 0.02 0.02 0.05 0.05 2.4e-03 2.6e-03 7.9e-06 3.5e-06
5 Brain alternative TSS XM_006251383.4 0.23 0.09 3.3e-10 0.08 0.12 0.13 0.13 1.1e-07 2.3e-11 8.5e-12 6.9e-12
6 Brain isoform ratio XM_006251383.4 0.07 0.04 8.3e-06 0.05 0.05 0.04 0.06 3.5e-05 1.6e-05 1.3e-04 7.5e-06
7 Brain gene expression Gal3st1 0.32 0.11 1.6e-15 0.13 0.18 0.19 0.2 2.2e-12 2.9e-16 1.2e-17 3.3e-18
8 PL isoform ratio XM_006251382.4 0.13 0.06 8.3e-07 0.05 0.04 0.06 0.06 1.3e-06 2.4e-05 7.4e-07 5.0e-07
9 Eye gene expression Gal3st1 0.36 0.15 2.7e-03 0.09 0.17 0.15 0.14 1.7e-02 1.4e-03 2.7e-03 4.3e-03
10 NAcc isoform ratio NM_001109447.1 0.08 0.05 5.2e-04 0.02 0.02 0.02 0.03 4.2e-03 1.2e-03 1.7e-03 3.0e-04
11 NAcc gene expression Gal3st1 0.12 0.06 3.7e-10 0.1 0.1 0.1 0.1 1.8e-11 4.6e-11 8.2e-12 7.6e-12
12 Brain isoform ratio NM_001109447.1 0.23 0.09 5.1e-14 0.15 0.17 0.18 0.18 4.1e-14 2.0e-15 8.7e-17 1.1e-16
13 Brain isoform ratio XM_006251382.4 0.24 0.09 3.3e-13 0.16 0.16 0.16 0.17 6.6e-15 4.0e-15 4.1e-15 1.1e-15
14 pVTA isoform ratio NM_001109447.1 0.31 0.12 2.5e-05 0.07 0.08 0.12 0.12 5.6e-04 2.8e-04 7.3e-06 6.5e-06
15 Brain mRNA stability Gal3st1 0.05 0.03 8.7e-05 0.03 0.05 0.06 0.05 8.8e-04 2.2e-05 3.9e-06 1.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.61.11.81.00.51.11.0-1.2-1.31.4-1.2-0.31.30.2-1.3-1.30.80.2
Area under the delay curve4.85.18.6-2.92.4-2.9-2.32.72.9-2.41.9-2.2-1.8-1.81.61.0-1.72.2
BMI with tail0.61.95.3-1.71.2-1.8-0.72.12.3-1.90.81.2-1.30.31.10.9-0.70.2
BMI without tail0.30.51.8-1.41.2-0.40.20.50.6-0.3-0.21.20.01.2-0.1-0.40.7-0.6
Body weight0.73.013.1-3.63.2-2.3-0.92.12.0-1.40.4-0.7-0.6-0.50.0-0.5-0.11.7
Weight adjusted by age0.50.62.9-1.71.2-1.1-0.51.01.0-0.80.40.2-0.50.10.4-0.1-0.00.4
Bone surface0.10.10.5-0.30.7-0.3-0.30.30.2-0.10.2-0.6-0.1-0.30.0-0.1-0.20.3
Bone volume0.10.20.6-0.10.80.20.1-0.4-0.40.5-0.4-0.70.6-0.1-0.6-0.70.30.3
Breakpoint value in progressive ratio session0.20.20.7-0.40.7-0.5-0.20.50.3-0.30.1-0.8-0.1-0.8-0.2-0.1-0.40.7
Number of licking bursts1.11.33.6-1.91.90.20.1-0.6-0.81.0-0.9-0.91.30.4-1.4-1.61.30.6
Context. condit. distance diff. score1.01.23.61.9-1.31.31.5-1.1-0.90.8-1.01.70.71.1-0.4-0.10.6-0.9
Locomotion velocity, session 11.41.53.50.9-1.7-0.6-1.30.70.8-1.11.5-0.4-1.5-1.01.71.9-1.6-0.3
Locomotion distance, session 10.40.63.01.7-1.00.90.7-0.7-0.60.5-0.41.00.20.5-0.10.1-0.0-0.7
Locomotion velocity, session 21.31.54.61.4-1.7-0.3-1.10.20.2-0.61.1-1.8-1.0-2.11.11.4-1.50.8
Locomotion distance, session 21.11.57.42.7-2.60.8-0.1-0.4-0.1-0.10.60.9-0.60.21.01.3-0.9-1.3
Locomotion velocity, session 30.30.42.01.4-0.80.50.9-0.3-0.30.1-0.21.0-0.10.4-0.00.2-0.30.2
Locomotion distance, session 31.31.42.5-0.2-0.4-1.1-1.31.31.3-1.41.6-0.4-1.6-0.71.51.5-1.50.3
Stereotopy head waving bouts, day 30.60.71.91.4-0.91.10.7-1.1-1.00.9-0.60.80.60.5-0.6-0.30.6-0.9
Stereotopy head waving duration, day 31.11.33.51.9-1.51.40.9-1.2-1.10.9-0.61.60.51.2-0.30.00.6-1.6
Locomotion velocity, session 70.80.91.50.1-0.6-1.0-1.21.01.0-1.11.1-0.4-1.1-1.20.91.0-0.9-0.0
Locomotion distance, session 70.40.52.61.6-1.30.1-0.30.30.4-0.50.50.6-0.6-0.20.81.0-0.8-0.5
Stereotopy head waving bouts, day 70.00.00.20.10.20.00.20.20.1-0.10.00.4-0.10.50.20.2-0.20.3
Stereotopy head waving duration, day 70.10.10.4-0.60.7-0.20.10.30.2-0.20.00.5-0.10.70.1-0.10.00.1
Locomotion velocity, session 80.70.84.32.0-2.11.10.3-1.0-0.90.6-0.00.30.1-0.10.20.6-0.1-0.9
Locomotion distance, session 83.04.515.33.9-3.22.61.9-2.1-1.91.6-1.22.81.01.8-0.40.10.9-2.4
Degree of sensitization distance2.62.65.82.4-1.62.01.6-2.0-1.81.7-1.51.51.51.1-1.2-0.81.3-1.6
Degree of sensitization stereotypy0.20.20.9-0.91.0-0.30.00.40.3-0.2-0.00.1-0.00.40.0-0.20.00.5
Conditioned locomotion0.40.41.20.90.20.80.8-0.4-0.30.6-0.70.90.71.1-0.5-0.50.3-0.1
Cocaine response after cond. corrected0.50.51.8-0.71.1-0.7-0.50.60.4-0.30.4-1.4-0.4-0.80.20.0-0.51.3
Cocaine response after cond. not corrected0.91.04.4-1.52.1-1.0-0.30.70.5-0.20.0-1.6-0.1-0.9-0.3-0.5-0.21.9
Cocaine response before conditioning0.20.20.7-0.70.8-0.40.40.20.1-0.0-0.60.00.2-0.3-0.5-0.50.40.7
Saline control response1.11.54.41.5-2.1-0.5-0.60.70.9-1.21.10.8-1.5-0.61.61.8-1.3-0.7
Bone: connectivity density0.30.40.80.90.20.80.8-0.7-0.80.8-0.80.20.70.4-0.7-0.70.40.1
Bone: cortical apparent density0.10.10.7-0.20.20.3-0.0-0.1-0.10.1-0.10.50.30.7-0.1-0.20.2-0.8
Bone: cortical area1.31.910.8-3.32.2-1.9-0.91.61.4-1.20.6-0.5-0.8-0.50.2-0.10.10.8
Bone: cortical porosity0.30.42.1-0.41.1-0.50.00.30.2-0.0-0.2-0.90.2-0.7-0.4-0.60.01.4
Bone: cortical porosity0.10.10.9-0.20.6-0.20.30.10.10.1-0.3-0.20.2-0.1-0.3-0.40.20.9
Bone: cortical thickness0.81.38.4-2.92.3-1.4-0.41.21.0-0.80.10.1-0.30.1-0.3-0.60.50.6
Bone: cortical thickness0.70.83.70.10.40.80.7-0.5-0.40.6-0.61.70.71.9-0.5-0.60.8-1.1
Bone: cortical tissue density0.10.10.6-0.20.20.2-0.1-0.0-0.00.1-0.00.40.20.6-0.1-0.20.2-0.8
Condit. Reinf. active minus inactive responses1.61.83.50.5-1.0-1.2-1.41.31.5-1.51.7-0.3-1.7-1.01.81.9-1.6-0.4
Condit. Reinf. active-inactive response ratio2.52.76.71.3-2.4-0.8-1.51.11.3-1.62.0-0.0-2.0-0.92.42.6-1.9-1.0
Condit. Reinf. active responses0.60.81.60.4-0.9-0.6-0.90.80.9-0.91.10.3-1.0-0.31.21.3-0.8-1.0
Condit. Reinf. inactive responses0.60.71.5-0.91.20.30.5-0.5-0.50.7-0.90.40.90.6-1.1-1.21.2-0.4
Incentive salience index mean1.61.93.0-0.4-0.3-1.6-1.61.71.7-1.71.7-0.5-1.7-1.21.71.6-1.5-0.1
Condit. Reinf. lever presses0.50.71.4-1.10.6-1.2-0.91.11.1-1.00.8-0.0-0.9-0.40.70.6-0.5-0.2
Condit. Reinf. active minus inactive responses0.20.21.10.5-0.90.20.3-0.3-0.30.1-0.11.0-0.10.2-0.10.10.2-0.7
Condit. Reinf. active-inactive response ratio0.30.30.70.2-0.3-0.5-0.50.70.7-0.70.70.0-0.8-0.40.70.7-0.80.1
Condit. Reinf. active responses0.50.73.81.6-1.90.20.3-0.1-0.0-0.30.21.3-0.5-0.10.40.7-0.4-0.8
Condit. Reinf. inactive responses0.70.94.01.7-2.00.80.7-0.7-0.60.3-0.41.50.10.40.00.30.2-1.1
Condit. Reinf. lever presses0.30.41.70.7-1.1-0.20.10.40.5-0.60.21.3-0.50.00.50.5-0.4-0.5
Condit. Reinf. lever reinforcers received0.50.73.41.5-1.8-0.00.10.20.3-0.60.31.4-0.8-0.10.70.9-0.7-0.5
Conditioned reinforcement - actives0.90.91.6-1.00.9-1.1-0.51.31.3-1.10.8-0.7-0.9-0.60.80.8-0.81.2
Conditioned reinforcement - inactives2.12.33.8-1.51.2-2.0-1.21.91.8-1.71.2-1.6-1.4-1.61.11.0-1.41.9
Conditioned locomotion0.30.41.6-1.11.3-0.7-0.30.40.5-0.2-0.1-0.7-0.0-0.50.0-0.20.30.9
Patch foraging indifference point 0 sec0.10.10.4-0.60.40.0-0.4-0.1-0.20.2-0.0-0.10.30.2-0.3-0.40.4-0.5
Patch foraging indifference point AUC1.31.52.81.0-1.4-0.8-1.40.80.9-1.21.6-0.3-1.6-1.21.51.7-1.3-1.1
Delay disc. indifference point, 0s delay3.03.37.3-2.02.6-2.1-1.22.52.6-1.91.2-1.2-1.2-0.61.10.6-1.52.7
Delay disc. indifference point, 16s delay3.53.66.3-2.01.5-2.3-2.02.12.1-1.81.6-2.5-1.5-2.31.31.0-1.72.2
Delay disc. indifference point, 2s delay2.73.06.8-2.42.6-2.2-1.32.22.3-1.71.1-1.5-1.1-0.80.90.4-1.12.4
Delay disc. indifference point, 24s delay2.82.74.5-1.41.6-1.9-1.51.92.1-1.71.4-1.8-1.4-1.41.31.0-1.72.1
Delay disc. indifference point, 4s delay3.63.86.7-2.22.0-2.6-1.72.42.5-2.11.5-1.8-1.7-1.71.30.8-1.52.3
Delay disc. indifference point, 8s delay1.61.73.1-1.50.4-1.7-1.71.51.6-1.51.5-0.8-1.4-0.91.31.2-1.10.0
Indifference point function ln k0.81.12.5-0.21.30.41.2-0.8-0.81.0-1.5-0.21.3-0.0-1.6-1.61.01.2
Indifference point function log k0.81.12.5-0.21.30.41.2-0.8-0.81.0-1.5-0.21.3-0.0-1.6-1.61.01.2
Patch foraging total patch changes 0 sec0.10.10.6-0.80.3-0.2-0.70.10.1-0.10.3-0.2-0.00.00.0-0.10.1-0.5
Patch foraging total patch changes 12 sec0.10.10.4-0.50.50.0-0.3-0.0-0.00.10.00.20.20.3-0.2-0.20.3-0.7
Patch foraging total patch changes 18 sec1.51.93.6-0.5-0.7-1.2-1.91.31.3-1.51.9-0.5-1.7-0.91.81.8-1.4-0.6
Patch foraging total patch changes 24 sec1.41.76.11.8-2.30.90.1-0.4-0.2-0.00.52.1-0.41.51.01.2-0.3-2.5
Patch foraging total patch changes 6 sec0.50.71.4-0.4-0.3-0.9-1.20.80.8-1.01.1-0.6-1.1-0.90.90.9-0.7-0.4
Patch foraging time to switch 0 sec2.13.29.0-0.30.72.02.0-1.6-1.51.9-1.91.72.33.0-1.7-1.72.0-0.9
Patch foraging water rate 0 sec1.42.24.4-1.40.0-2.1-2.01.51.3-1.61.7-1.0-1.9-2.11.31.2-0.90.2
Patch foraging water rate 12 sec0.40.61.6-0.3-0.6-0.9-0.90.70.7-0.90.90.3-1.3-0.70.90.9-0.4-0.4
Patch foraging water rate 18 sec1.82.44.8-0.00.51.31.6-1.7-1.71.7-1.81.51.61.5-1.9-1.92.2-0.8
Patch foraging water rate 24 sec0.20.20.8-0.8-0.7-0.3-0.3-0.2-0.2-0.10.20.8-0.5-0.00.10.30.6-0.9
Patch foraging water rate 6 sec0.10.10.9-0.90.0-0.5-0.4-0.0-0.1-0.10.10.5-0.3-0.2-0.1-0.10.6-0.5
Seeking ratio, delayed vs. immediate footshock0.60.73.50.7-0.7-0.5-0.50.20.2-0.40.5-1.3-0.7-1.90.40.5-0.81.1
Distance traveled before self-admin0.40.51.50.6-0.4-0.3-0.90.40.3-0.40.7-1.2-0.6-1.20.70.4-0.90.2
Distance traveled after self-admin0.30.40.90.00.1-0.4-0.90.70.7-0.60.8-0.6-0.6-0.50.80.4-0.90.1
Extensor digitorum longus weight1.14.318.1-4.33.3-2.8-2.22.22.0-1.61.2-1.9-1.1-1.60.4-0.2-0.41.6
Bone: elastic displacement1.41.62.40.10.41.31.4-1.4-1.41.4-1.41.11.41.4-1.5-1.41.6-0.7
Bone: elastic work2.12.75.6-1.31.71.01.4-1.4-1.61.7-1.80.91.81.7-2.1-2.12.4-0.9
Bone: endosteal estimation0.00.10.2-0.50.2-0.20.0-0.1-0.10.2-0.2-0.30.2-0.2-0.3-0.20.30.2
Bone: endosteal perimeter0.40.92.2-1.50.8-1.3-0.81.00.9-0.90.7-1.1-0.8-1.10.50.3-0.51.1
Epididymis fat weight0.71.73.0-0.71.61.01.6-0.9-0.91.3-1.50.71.51.5-1.6-1.71.60.4
Delta time in closed arm before/after self-admin2.02.04.62.1-0.31.62.1-1.5-1.51.5-1.81.11.40.7-1.5-1.20.90.2
Delta time in open arm before/after self-admin3.13.05.1-2.30.7-2.2-2.32.02.1-2.01.9-1.6-1.6-1.41.51.2-1.40.8
Diff in mean of infusions in LGA sessions0.10.10.60.30.1-0.10.20.40.4-0.30.2-0.2-0.20.10.30.2-0.80.7
Delay discount exponential model param4.64.88.32.9-2.32.92.3-2.7-2.82.4-1.92.11.81.7-1.6-1.11.7-2.0
Extinction: sum of active levers before priming2.72.74.7-0.20.3-1.7-1.41.81.7-1.71.5-1.8-1.6-2.11.41.4-2.22.1
Active lever presses in extinction session 61.00.96.3-0.61.6-0.7-0.00.70.5-0.3-0.2-1.40.1-1.1-0.4-0.5-0.62.5
Bone: final force0.20.31.3-1.20.2-0.3-0.10.20.2-0.10.11.0-0.10.90.00.00.6-1.0
Bone: final moment0.20.31.7-1.30.6-0.2-0.00.00.00.1-0.10.50.20.6-0.3-0.40.7-0.5
Food consumed during 24 hour testing period0.81.02.3-0.5-0.9-1.0-1.50.70.7-1.01.3-0.7-1.2-1.41.11.1-0.8-0.4
Glucose16.424.738.3-3.2-0.1-5.5-6.25.25.0-5.45.9-5.1-5.6-5.65.45.2-5.22.0
Heart weight0.20.20.90.6-1.00.50.4-0.4-0.40.3-0.00.7-0.10.60.10.40.1-0.8
Delay discount hyperbolic model param4.95.28.92.9-2.33.02.3-2.8-3.02.5-2.02.01.91.6-1.7-1.11.7-2.2
Intermittent access intake day 1-15 change1.31.21.8-0.60.2-1.3-1.11.31.3-1.31.2-1.0-1.3-1.01.31.3-1.10.8
Intermittent access intake escalation0.70.70.9-0.50.2-1.0-0.70.90.9-0.90.8-0.8-0.8-0.80.90.9-0.71.0
Intermittent access intake escalation 20.10.10.2-0.3-0.3-0.0-0.4-0.2-0.20.10.1-0.20.0-0.00.20.20.3-0.4
Intermitt. access day 1 inactive lever presses0.30.40.70.6-0.4-0.70.10.60.6-0.70.20.1-0.8-0.70.80.8-0.70.6
Intermitt. access day 15 inactive lever presses2.32.54.5-1.0-0.8-1.9-1.71.81.8-1.91.9-0.2-2.1-1.12.01.9-1.3-0.3
Intermitt. access escalation Index0.40.31.40.4-0.9-0.0-0.30.20.3-0.40.50.9-0.50.40.60.7-0.5-1.2
Intermittent access day 1 total infusions0.10.10.5-0.70.40.0-0.10.20.2-0.10.20.2-0.00.60.1-0.00.1-0.2
Intermittent access day 15 total infusions0.80.81.5-1.20.6-1.0-1.01.21.2-1.11.0-0.6-0.9-0.31.10.9-0.60.6
Intermittent access terminal intake (last 3 days)0.30.30.6-0.80.1-0.6-0.60.60.6-0.60.6-0.3-0.5-0.10.70.6-0.30.1
Intermittent access total infusions0.20.20.8-0.90.6-0.5-0.40.50.5-0.40.4-0.7-0.3-0.30.30.2-0.10.6
Intermittent access day 1 locomotion0.50.51.61.3-1.11.00.3-0.6-0.50.40.00.90.10.80.30.30.2-1.2
Intermittent access day 15 total locomotion0.91.03.0-1.71.3-1.3-0.91.41.4-1.10.8-0.3-0.8-0.10.90.6-0.40.5
Intermittent access total locomotion0.80.91.5-0.60.3-1.0-1.01.21.2-1.21.2-0.8-1.2-0.81.11.0-0.90.6
Intermittent access standard deviation0.30.31.10.4-0.80.40.3-0.4-0.20.2-0.01.1-0.10.80.40.40.5-1.0
Left kidney weight1.13.05.50.10.61.52.1-1.7-1.71.9-2.11.52.01.8-2.1-2.02.4-0.7
Right kidney weight1.85.09.40.71.12.13.1-2.1-1.92.4-3.01.82.72.3-2.7-2.72.5-0.1
Cocaine induced anxiety1.82.04.6-1.0-0.1-1.8-2.11.31.4-1.41.5-1.5-1.5-2.01.51.3-1.10.4
Post-drug Anxiety0.80.92.1-0.60.1-1.2-1.20.90.9-0.90.9-1.2-1.0-1.40.80.7-0.90.8
Baseline Anxiety0.30.30.8-0.50.90.40.7-0.2-0.20.4-0.5-0.10.70.8-0.8-0.70.10.6
Tail length0.51.55.6-2.12.4-0.30.1-0.3-0.70.8-0.8-1.30.9-0.3-1.4-1.81.30.8
Length with tail0.62.38.5-2.92.9-0.70.1-0.1-0.50.8-0.9-1.61.1-0.4-1.7-2.01.41.5
Length without tail0.40.83.6-1.91.4-1.1-0.60.70.6-0.30.2-1.3-0.1-0.9-0.2-0.3-0.01.3
Times rat made contact with spout1.82.03.80.6-2.0-0.9-1.60.91.0-1.31.7-1.1-1.7-1.81.81.9-1.6-0.2
Lifetime Intake0.20.20.7-0.80.8-0.4-0.30.40.3-0.30.2-0.7-0.1-0.30.0-0.0-0.00.7
Liver weight, left3.35.39.22.4-0.42.73.0-2.6-2.62.7-2.81.62.51.8-2.5-2.32.2-0.4
Liver weight, right3.65.912.92.2-1.22.82.9-2.4-2.22.3-2.53.62.23.3-1.9-1.72.3-2.0
Locomotor activity0.71.12.6-0.7-0.4-1.0-1.60.70.6-0.81.4-1.5-1.2-1.60.90.9-0.80.2
Locomotor testing distance0.20.31.3-1.21.0-0.5-0.40.30.1-0.10.0-0.40.0-0.4-0.5-0.60.40.3
Locomotor testing rearing1.21.83.4-1.91.0-1.8-1.51.41.2-1.31.2-1.7-1.2-1.70.80.6-0.91.2
Locomotion in novel chamber0.81.02.50.70.11.11.6-0.9-0.91.1-1.21.31.01.5-1.0-0.80.70.0
Locomotion in novel chamber post-restriction0.91.14.72.2-2.10.60.1-0.00.2-0.40.51.0-0.60.41.21.4-1.0-1.0
Fecal boli incidents, locomotor time 10.20.21.01.0-0.80.3-0.2-0.3-0.30.10.2-0.2-0.2-0.60.10.2-0.30.2
Change in fecal boli incidents, locomotor task0.50.42.11.0-1.40.1-0.4-0.1-0.1-0.20.60.1-0.6-0.20.91.0-0.5-0.6
Time >=10cm from walls, locomotor time 10.70.73.30.20.30.91.1-0.6-0.40.7-0.81.20.91.8-0.5-0.40.8-0.8
Bouts of movement, locomotor time 10.20.31.20.1-0.3-0.2-0.20.40.5-0.30.5-0.0-0.40.10.71.1-1.10.2
Total resting periods, locomotor time 10.70.82.50.1-0.5-0.6-0.50.90.9-0.90.9-0.1-1.0-0.11.31.6-1.50.2
Rest time, locomotor task time 10.60.71.50.4-1.0-0.5-0.80.60.6-0.91.00.2-1.2-0.51.21.2-1.0-0.2
Distance moved, locomotor task time 11.21.32.6-0.50.81.10.7-1.2-1.21.5-1.10.21.61.1-1.6-1.41.5-0.9
Vertical activity count, locomotor time 10.60.61.50.40.11.00.4-1.1-1.01.2-0.7-0.61.20.3-0.9-0.70.6-0.3
Time >=10cm from walls, locomotor time 20.10.10.50.7-0.50.40.5-0.3-0.10.2-0.30.40.20.2-0.00.3-0.0-0.0
Bouts of movement, locomotor time 20.20.30.8-0.20.5-0.80.40.70.8-0.6-0.20.4-0.3-0.20.10.2-0.50.9
Total resting periods, locomotor time 20.40.51.3-0.20.3-1.00.01.01.1-0.90.20.4-0.7-0.30.50.7-0.80.7
Rest time, locomotor task time 20.20.21.10.7-1.10.20.0-0.2-0.30.00.10.6-0.20.20.30.4-0.2-0.7
Distance moved, locomotor task time 20.40.51.0-0.00.30.80.5-0.7-0.70.8-0.60.40.81.0-0.7-0.50.9-0.7
Vertical activity count, locomotor time 20.10.10.50.30.50.20.0-0.2-0.20.3-0.1-0.70.2-0.2-0.2-0.40.10.5
Light reinforcement 10.10.31.6-1.30.9-0.3-0.10.20.00.0-0.00.5-0.00.7-0.2-0.20.4-0.4
Light reinforcement 20.81.12.2-0.90.40.70.6-0.9-1.01.0-0.71.20.91.5-1.2-1.11.5-1.2
Bone: marrow area0.00.00.1-0.40.1-0.2-0.0-0.10.00.1-0.1-0.30.1-0.2-0.2-0.10.20.2
Bone: maximum diameter2.03.714.2-3.81.9-2.8-2.02.32.1-2.01.6-1.5-1.7-1.61.00.8-0.70.9
Bone: maximum force0.20.41.4-1.20.50.00.3-0.2-0.30.3-0.40.70.40.8-0.5-0.61.1-0.9
Bone: maximum moment0.30.51.8-1.30.80.10.4-0.4-0.50.6-0.60.30.70.5-0.9-1.01.3-0.4
Mean time between licks in bursts0.60.92.60.8-1.6-0.1-1.1-0.0-0.1-0.31.0-0.8-0.9-0.91.01.3-0.6-1.3
Mean num. licks in bursts2.83.49.52.2-3.1-0.7-1.01.11.3-1.71.90.1-2.2-1.42.42.7-2.2-0.6
Cd content in liver1.01.12.71.1-0.71.40.7-1.1-1.11.0-0.61.30.81.5-0.5-0.40.9-1.7
Co content in liver0.50.62.0-0.10.4-1.0-0.51.01.1-0.90.5-0.5-0.7-1.00.40.4-1.01.4
Cu content in liver0.10.10.50.20.6-0.0-0.00.10.00.1-0.1-0.70.2-0.4-0.2-0.2-0.40.7
Fe content in liver0.91.14.21.5-2.0-0.2-0.70.20.2-0.51.0-0.7-1.0-1.31.11.4-1.2-0.1
K content in liver0.50.52.9-0.91.7-0.50.10.40.3-0.0-0.4-0.70.3-0.3-0.5-0.7-0.21.4
Mg content in liver1.11.23.8-1.91.9-1.4-0.51.11.0-0.70.2-1.2-0.3-1.1-0.1-0.2-0.51.6
Mn content in liver0.20.20.9-0.10.9-0.30.10.10.10.1-0.4-0.60.3-0.7-0.6-0.70.01.0
Na content in liver5.86.19.0-2.01.1-3.0-2.72.92.8-2.72.5-2.7-2.6-2.82.22.0-2.52.0
Rb content in liver0.40.51.6-1.31.2-0.6-0.90.60.5-0.30.4-1.0-0.1-0.40.1-0.1-0.40.6
Se content in liver0.91.13.8-1.91.9-1.0-0.40.60.4-0.2-0.0-1.8-0.0-1.2-0.3-0.5-0.01.5
Sr content in liver0.80.81.6-1.0-0.6-1.0-1.30.80.8-0.91.2-0.4-1.0-0.71.01.0-0.5-0.3
Zn content in liver0.40.41.2-1.10.40.0-0.2-0.5-0.70.7-0.4-0.30.5-0.1-0.8-0.81.0-0.9
Bone: minimum diameter0.10.20.5-0.60.40.10.5-0.3-0.40.4-0.60.30.40.2-0.7-0.60.70.1
Time in familiar zone, hab. session 11.11.13.41.1-1.31.30.6-1.1-1.00.9-0.41.10.71.3-0.2-0.10.8-1.9
Time in novel zone, hab. session 10.70.73.0-1.21.5-0.8-0.10.40.3-0.2-0.2-1.00.0-1.0-0.6-0.7-0.01.7
Total zone transitions, hab. session 10.50.63.11.2-1.80.2-0.60.00.1-0.40.70.4-0.7-0.10.91.0-0.7-0.9
Total locomotion distance, hab. session 10.50.71.30.8-0.8-0.5-0.80.60.6-0.80.9-0.7-0.9-1.01.01.0-1.10.5
Locomotion velocity, hab. session 10.60.91.90.9-1.1-0.6-0.80.70.8-1.01.1-0.2-1.2-0.81.31.4-1.30.1
Time in familiar zone, hab. session 22.72.75.02.2-1.32.22.0-1.9-1.71.7-1.51.81.51.9-1.0-0.71.2-1.4
Time in novel zone, hab. session 21.71.76.1-2.51.1-1.8-1.81.41.3-1.21.2-1.1-1.1-1.20.60.4-0.40.4
Total zone transitions, hab. session 20.81.12.5-0.1-0.8-0.9-1.60.80.9-1.01.4-0.1-1.3-0.61.41.3-0.9-0.9
Total locomotion distance, hab. session 21.01.33.2-0.6-0.6-1.2-1.81.01.1-1.21.5-0.5-1.4-0.91.51.4-0.9-0.7
Locomotion velocity, hab. session 21.21.63.7-0.8-0.3-1.4-1.91.21.2-1.31.6-0.8-1.5-1.11.51.4-1.1-0.3
Novel to familiar place preference ratio4.54.66.8-0.6-0.3-2.3-2.42.52.5-2.62.5-1.3-2.6-2.02.42.3-2.61.2
Novelty place preference3.94.05.8-0.7-0.2-2.2-2.22.32.3-2.42.3-1.3-2.4-2.02.22.1-2.41.3
Time in novel zone, NPP test3.53.65.4-0.7-0.3-2.1-2.12.22.2-2.32.2-1.2-2.3-1.92.12.0-2.21.1
Total zone transitions, NPP test0.10.10.30.50.10.20.4-0.2-0.10.2-0.40.50.30.3-0.3-0.30.1-0.0
Total locomotion distance, NPP test0.10.10.30.30.1-0.4-0.20.50.6-0.40.2-0.1-0.2-0.40.30.2-0.50.4
Locomotion velocity, NPP test0.20.30.50.20.4-0.5-0.40.60.7-0.50.3-0.5-0.4-0.60.40.3-0.70.7
Intraocular pressure1.21.63.3-0.0-1.7-0.7-1.50.81.0-1.21.70.6-1.60.01.81.8-1.0-1.6
Delta distance traveled before/after self-admin0.10.10.7-0.40.3-0.00.10.30.4-0.20.10.6-0.10.80.30.2-0.1-0.0
Delta ambulatory time before/after self-admin0.10.10.50.40.10.50.5-0.2-0.10.2-0.30.40.30.7-0.0-0.0-0.00.2
Parametrial fat weight2.44.68.2-0.5-0.7-2.1-2.52.22.4-2.42.6-1.5-2.5-2.02.72.5-2.90.6
Pavlov. Cond. lever latency0.40.51.9-0.30.2-0.5-0.50.40.3-0.40.5-1.4-0.5-1.00.50.4-0.71.2
Pavlov. Cond. magazine entry latency0.40.51.81.4-1.40.80.4-0.6-0.60.4-0.10.90.10.40.00.10.2-1.2
Pavlov. Cond. change in total contacts1.21.33.0-0.4-0.3-1.2-1.71.21.3-1.31.6-0.6-1.3-0.91.31.2-1.2-0.4
Pavlov. Cond. index score0.50.61.91.3-1.10.80.6-0.6-0.50.4-0.31.40.30.8-0.2-0.00.3-1.3
Pavlov. Cond. latency score0.60.82.31.2-1.10.90.7-0.7-0.60.5-0.51.50.41.0-0.3-0.20.5-1.5
Pavlov. Cond. lever contacts0.30.31.50.5-0.60.40.4-0.3-0.20.3-0.31.20.30.7-0.2-0.10.5-1.2
Pavlov. Cond. magazine entry number0.60.73.3-1.61.8-0.30.20.1-0.10.3-0.5-0.80.60.1-0.8-0.90.51.2
Pavlov. Cond. intertrial magazine entries0.70.83.5-0.71.9-0.20.8-0.0-0.10.4-1.1-0.20.9-0.0-1.3-1.40.71.2
Pavlov. Cond. lever-magazine prob. diff.0.50.62.01.3-1.10.80.7-0.6-0.50.5-0.41.40.40.8-0.3-0.10.4-1.3
Pavlov. Cond. response bias0.10.10.40.6-0.5-0.1-0.10.20.2-0.20.20.3-0.3-0.20.30.3-0.2-0.4
Pavlov. Cond. lever latency0.91.26.4-2.02.5-0.1-0.1-0.2-0.50.7-0.6-1.10.90.4-1.1-1.41.00.7
Pavlov. Cond. magazine entry latency0.00.00.1-0.3-0.1-0.2-0.00.20.3-0.20.20.3-0.20.10.10.1-0.20.1
Pavlov. Cond. change in total contacts0.50.63.21.1-1.80.0-0.10.20.4-0.50.51.1-0.70.00.70.9-0.6-0.8
Pavlov. Cond. index score0.40.52.91.2-1.70.10.20.10.3-0.40.31.1-0.60.10.60.8-0.5-0.7
Pavlov. Cond. latency score0.40.52.71.2-1.60.10.30.10.2-0.30.21.1-0.50.10.50.7-0.5-0.6
Pavlov. Cond. lever contacts1.11.47.62.3-2.80.10.10.20.5-0.70.61.2-0.9-0.41.11.4-1.1-0.9
Pavlov. Cond. magazine entry number0.00.00.20.40.40.0-0.0-0.0-0.00.0-0.1-0.30.2-0.2-0.1-0.10.00.2
Pavlov. Cond. intertrial magazine entries0.00.10.40.40.3-0.20.00.10.1-0.0-0.2-0.20.0-0.6-0.2-0.1-0.10.3
Pavlov. Cond. lever-magazine prob. diff.0.40.52.71.1-1.60.30.3-0.10.1-0.20.11.1-0.30.20.40.6-0.3-0.7
Pavlov. Cond. response bias0.50.74.01.4-2.00.0-0.00.20.5-0.60.50.9-0.7-0.30.81.0-0.8-0.6
Time in closed arm before self-admin0.70.81.9-0.3-0.20.80.4-1.1-1.01.0-0.70.90.91.1-0.8-0.71.2-1.4
Time in closed arm after self-admin2.92.94.81.3-0.01.92.2-1.9-2.02.0-2.11.41.91.2-2.0-1.81.9-0.7
Time in open arm before self-admin0.00.00.10.20.30.10.30.1-0.10.1-0.20.20.00.2-0.1-0.10.20.0
Time in open arm after self-admin2.02.23.6-0.7-0.5-1.6-1.71.71.7-1.81.8-0.6-1.8-1.01.91.9-1.60.1
Bone: periosteal estimation0.30.75.0-2.21.3-1.1-0.50.70.6-0.50.2-0.3-0.3-0.3-0.2-0.30.40.4
Bone: periosteal perimeter1.22.08.3-2.91.8-2.1-1.11.81.6-1.40.9-0.9-1.1-1.00.60.3-0.51.3
Bone: post-yield work0.20.31.5-0.40.30.1-0.0-0.5-0.50.5-0.3-1.20.5-0.8-0.6-0.70.30.8
Progressive ratio test 1 active lever presses1.71.83.2-0.70.7-1.5-1.01.61.5-1.41.2-1.7-1.3-1.61.01.0-1.61.8
Progressive ratio test 1 breakpoint1.21.33.2-0.50.7-1.2-0.61.41.3-1.20.8-1.4-1.0-1.30.80.8-1.41.8
Progressive ratio test 1 inactive lever presses2.62.95.2-1.81.4-2.3-1.72.01.9-1.81.3-2.0-1.5-2.01.10.7-1.31.9
Progressive ratio test 2 active lever presses0.40.40.8-0.70.5-0.6-0.70.70.6-0.60.7-0.9-0.5-0.40.50.5-0.50.7
Progressive ratio test 2 breakpoint0.60.61.1-0.60.2-0.7-1.00.90.8-0.91.1-0.9-0.9-0.60.90.9-0.80.4
Progressive ratio test 2 inactive lever presses1.82.14.8-2.20.5-1.7-1.61.81.8-1.71.7-0.5-1.5-0.41.61.4-0.90.2
Incentive Sensitization - Responses0.10.10.4-0.60.00.0-0.50.20.2-0.10.5-0.2-0.20.40.30.3-0.1-0.3
Incentive Sensitization - Breakpoint0.10.10.6-0.80.10.0-0.50.20.2-0.10.5-0.1-0.10.50.30.20.0-0.4
Sum of active levers in priming session hrs 5-60.50.52.5-0.81.2-0.70.00.90.7-0.4-0.1-0.7-0.1-0.4-0.1-0.1-0.51.6
Progressive ratio0.30.30.7-0.60.40.50.3-0.6-0.50.7-0.5-0.30.70.4-0.6-0.90.70.3
Food seeking constrained by brief footshock0.81.04.3-2.12.1-0.9-0.50.60.6-0.1-0.1-1.10.2-0.2-0.5-0.90.11.3
Seeking ratio, punishment vs. effort0.50.61.7-0.91.0-1.3-0.61.11.0-0.90.5-0.4-0.8-0.80.30.3-0.50.6
Retroperitoneal fat weight0.20.61.40.2-0.6-0.2-0.50.60.8-0.80.80.8-0.80.61.21.1-0.6-0.9
Reaction time number correct0.20.31.1-0.0-1.1-0.1-0.5-0.2-0.3-0.10.5-0.1-0.6-0.60.40.50.4-1.0
Reaction time mean minus median0.10.10.7-0.00.00.00.2-0.1-0.10.1-0.2-0.70.2-0.5-0.0-0.0-0.10.8
Reaction time mean minus median AUC0.10.10.6-0.70.7-0.20.20.20.2-0.1-0.2-0.20.2-0.0-0.1-0.20.10.6
Reaction time num false alarms0.30.41.0-0.90.9-0.6-0.30.91.0-0.70.30.2-0.20.40.2-0.1-0.40.7
Reaction time num false alarms AUC0.30.41.4-1.01.2-0.30.20.50.6-0.2-0.20.60.30.9-0.3-0.60.20.6
Reaction time trials correct on left0.20.31.1-0.0-1.1-0.1-0.5-0.2-0.3-0.10.5-0.1-0.6-0.60.40.50.4-1.0
Reaction time trials on left0.20.31.20.0-1.1-0.1-0.4-0.2-0.3-0.10.5-0.0-0.6-0.60.40.50.4-1.0
Reaction time mean0.20.30.70.30.40.70.7-0.5-0.50.7-0.7-0.30.80.2-0.6-0.60.40.7
Reaction time mean AUC0.40.51.00.40.50.81.0-0.7-0.70.8-0.9-0.11.00.4-0.8-0.80.60.7
Median of all reaction times0.30.50.90.50.50.80.9-0.6-0.60.8-0.9-0.10.90.4-0.8-0.80.50.7
Reaction time omissions0.10.10.50.7-0.30.00.60.10.1-0.1-0.10.1-0.2-0.10.20.3-0.40.6
Reaction time false alarm rate0.50.73.1-1.01.8-0.10.50.50.60.0-0.70.60.71.2-0.7-1.10.21.1
Reaction time premature initiation rate1.92.56.72.2-1.41.81.7-1.4-1.41.2-1.02.60.82.0-0.7-0.31.1-2.3
Reaction time premature initiations1.21.76.31.8-1.81.30.9-1.1-1.10.7-0.42.00.21.2-0.20.21.0-2.5
Std. dev. reaction times0.00.00.1-0.10.00.20.1-0.1-0.00.1-0.0-0.30.20.10.10.10.00.3
Reaction time trials completed0.20.31.20.0-1.1-0.1-0.4-0.2-0.3-0.10.5-0.0-0.6-0.60.40.50.4-1.0
Reaction time trials AUC0.20.20.8-0.1-0.9-0.1-0.5-0.2-0.3-0.10.4-0.2-0.5-0.70.20.40.4-0.9
Run reversals in cocaine runway, females0.30.31.10.9-0.70.80.3-0.3-0.00.20.10.60.11.00.50.4-0.3-0.6
Run reversals in cocaine runway, males0.10.10.2-0.40.1-0.4-0.10.30.2-0.30.1-0.2-0.2-0.20.20.1-0.0-0.2
Latency to leave start box in cocaine runway0.70.81.40.2-0.1-0.9-0.61.11.2-1.20.9-0.4-1.0-0.71.10.9-1.10.9
Latency to leave start box in cocaine runway, F0.30.30.7-0.70.2-0.6-0.10.80.8-0.70.30.7-0.50.40.60.3-0.1-0.1
Latency to leave start box in cocaine runway, M1.71.64.51.1-0.5-0.9-1.20.90.9-1.11.1-1.8-1.1-2.11.11.1-1.81.5
Std. dev. time between licks in bursts0.40.41.91.3-1.30.6-0.2-0.6-0.50.30.20.30.00.20.20.40.0-1.4
Total sessions with >9 infusions0.00.00.10.10.20.00.30.0-0.0-0.0-0.10.3-0.00.1-0.10.00.2-0.1
Short access day 1 total inactive lever presses0.80.93.2-1.81.2-1.2-1.20.80.7-0.70.6-1.2-0.5-1.10.1-0.10.00.7
Short access day 10 total inactive lever presses0.10.10.40.5-0.6-0.40.10.10.2-0.30.00.2-0.5-0.60.30.4-0.30.2
Short access day 1 total infusions0.20.20.6-0.20.80.10.7-0.1-0.20.3-0.6-0.00.50.2-0.7-0.60.40.6
Short access day 10 total infusions0.00.00.10.2-0.10.30.3-0.3-0.30.2-0.20.20.10.2-0.1-0.10.3-0.2
Short access total infusions0.20.30.6-0.20.60.40.7-0.4-0.50.5-0.60.10.60.3-0.8-0.70.70.2
Short access day 1 locomotion1.51.62.60.6-0.01.41.6-1.4-1.51.4-1.41.11.31.1-1.4-1.31.5-0.8
Short access day 10 total locomotion0.60.64.52.1-1.60.90.2-0.7-0.60.30.10.3-0.1-0.20.40.5-0.3-0.6
Short access total locomotion1.71.74.62.1-1.51.71.2-1.5-1.51.1-0.81.60.61.0-0.5-0.31.0-1.7
One hour access (0.3 mA shock)0.30.31.2-0.50.5-0.5-0.50.50.5-0.40.5-1.1-0.4-0.70.40.4-0.51.0
Compulsive drug intake2.02.07.02.6-1.21.82.0-1.6-1.51.4-1.51.21.10.8-1.0-0.70.60.0
One hour access (shock baseline)2.32.65.6-2.01.4-1.9-1.81.71.6-1.51.4-2.4-1.2-1.81.10.9-1.21.7
Social response proportion0.40.41.4-0.3-0.9-0.2-1.2-0.0-0.1-0.21.0-0.7-0.6-0.40.70.8-0.4-0.8
Social responses0.50.61.8-0.7-0.4-0.7-1.30.40.3-0.51.1-0.9-0.9-0.90.80.9-0.3-0.7
Social time0.30.41.00.7-0.91.00.5-1.0-0.90.8-0.40.00.60.4-0.3-0.20.5-0.6
Soleus weight0.51.57.4-2.72.2-0.60.1-0.1-0.30.5-0.8-0.50.8-0.1-1.4-1.71.50.9
Bone: stiffness0.20.20.90.2-0.5-0.4-0.10.60.7-0.60.30.9-0.50.20.50.6-0.2-0.5
Tibialis anterior weight0.72.39.1-3.01.9-2.0-1.61.61.5-1.31.0-1.6-0.9-1.20.50.1-0.41.6
Time to tail flick, vehicle, before self-admin0.30.31.2-0.70.50.30.4-0.2-0.10.3-0.40.80.41.1-0.4-0.50.70.1
Time to tail flick, vehicle, after self-admin0.10.10.60.8-0.60.30.3-0.00.1-0.10.10.3-0.20.20.50.4-0.60.5
Time to tail flick, test, before self-admin0.20.20.80.7-0.90.20.4-0.2-0.1-0.0-0.20.9-0.10.20.00.20.2-0.4
Time to tail flick, test, after self-admin0.60.63.8-2.00.8-1.2-1.00.70.5-0.60.4-0.4-0.4-0.6-0.1-0.30.5-0.4
Delta time to tail flick, vehicle, before/after SA0.40.41.51.2-1.00.2-0.20.00.1-0.20.4-0.3-0.4-0.40.70.8-1.00.2
Delta time to tail flick, test, before/after SA0.50.42.4-1.50.9-0.9-0.80.50.4-0.30.4-0.9-0.2-0.7-0.1-0.20.10.2
Tibia length1.13.25.5-0.41.31.52.0-1.6-1.61.9-2.21.22.21.9-2.3-2.32.3-0.5
Ambulatory time before self-admin0.30.31.40.60.0-0.1-0.60.10.0-0.10.3-1.2-0.1-1.10.2-0.2-0.60.6
Ambulatory time after self-admin0.20.31.00.60.1-0.0-0.60.30.3-0.20.5-1.0-0.2-0.70.50.0-0.80.6
Bone: tissue strength1.81.84.4-0.60.11.11.1-1.6-1.61.6-1.40.51.60.8-1.7-1.52.1-1.1
Total heroin consumption0.20.20.80.00.60.00.4-0.2-0.30.3-0.6-0.30.4-0.4-0.7-0.60.20.9
Bone: trabecular number0.71.02.10.41.00.91.0-1.0-1.11.2-1.3-0.21.30.4-1.4-1.40.90.3
Bone: trabecular spacing0.81.01.8-1.3-0.6-1.0-1.31.01.0-1.21.3-0.2-1.3-0.41.31.2-0.6-0.5
Bone: trabecular thickness2.83.35.71.20.91.92.1-2.0-2.12.3-2.30.42.41.1-2.4-2.21.70.1
Bone: trabecular tissue density0.10.10.70.6-0.80.10.0-0.00.2-0.10.10.1-0.0-0.10.30.4-0.2-0.3
Water consumed over 24 hours0.40.52.80.5-1.70.1-1.0-0.3-0.3-0.10.8-0.7-0.5-1.00.60.8-0.3-0.7
Number of responses in last shaping day0.20.20.60.7-0.50.20.10.00.2-0.10.10.8-0.00.60.40.2-0.1-0.5