Hub : Genes

Fxyd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr1_86289421_86289842 0.03 0.02 7.6e-03 0 -0 -0 -0 1.3e-01 5.7e-01 9.1e-01 9.0e-01
2 BLA isoform ratio XM_006228839.4 0.06 0.04 2.2e-03 0.03 0.03 0.01 0.03 6.4e-03 1.1e-02 7.3e-02 6.1e-03
3 Brain intron excision ratio chr1_86287668_86287965 0.07 0.05 2.8e-09 0.1 0.08 0.09 0.09 3.1e-09 6.9e-08 8.4e-09 8.3e-09
4 Brain intron excision ratio chr1_86287668_86288509 0.07 0.05 6.5e-09 0.09 0.08 0.09 0.09 5.2e-09 1.2e-07 1.5e-08 1.4e-08
5 Brain alternative TSS XM_039088784.1 0.02 0.02 2.3e-03 0.01 0.01 0.01 0.01 2.4e-02 2.8e-02 3.9e-02 3.6e-02
6 Brain isoform ratio XM_039088784.1 0.03 0.02 1.7e-03 0.02 0.02 0.01 0.02 7.9e-03 7.9e-03 2.4e-02 7.7e-03
7 PL isoform ratio XM_039088784.1 0.03 0.03 6.9e-03 0.02 0.02 0.01 0.02 2.1e-03 3.8e-03 4.6e-02 5.4e-03
8 PL intron excision ratio chr1_86287668_86287965 0.04 0.03 6.7e-04 0.03 0.02 0.02 0.02 6.8e-04 1.2e-03 2.4e-03 1.2e-03
9 PL intron excision ratio chr1_86287668_86288509 0.03 0.03 1.4e-03 0.02 0.02 0.02 0.02 1.6e-03 2.6e-03 5.9e-03 2.5e-03
10 Liver alternative TSS XM_006228839.4 0.02 0.02 7.4e-03 0 0.01 0.01 0 2.0e-01 2.7e-02 5.8e-02 1.8e-01
11 PL gene expression Fxyd1 0.08 0.05 1.6e-11 0.11 0.1 0.1 0.1 3.3e-12 5.9e-11 3.4e-11 2.2e-11
12 NAcc gene expression Fxyd1 0.04 0.02 1.7e-05 0.04 0.04 0.04 0.04 1.6e-05 8.6e-06 9.1e-06 1.8e-05
13 Liver alternative TSS XM_006228839.4 0.02 0.02 6.3e-03 0 0.01 0 0 1.9e-01 3.1e-02 8.9e-02 2.3e-01
14 Liver gene expression Fxyd1 0.09 0.05 9.4e-08 0.03 0.06 0.06 0.06 2.2e-04 2.7e-07 2.4e-07 1.5e-07
15 IL gene expression Fxyd1 0.14 0.1 3.2e-03 0.09 0.1 0.04 0.09 3.7e-03 2.9e-03 4.1e-02 3.0e-03
16 pVTA gene expression Fxyd1 0.23 0.14 1.8e-05 0.06 0.06 0.05 0.05 1.5e-03 1.1e-03 3.3e-03 3.7e-03
17 Brain gene expression Fxyd1 0.11 0.05 1.5e-12 0.14 0.14 0.15 0.15 9.2e-13 3.6e-13 1.7e-13 1.9e-13
18 NAcc isoform ratio NM_031648.2 0.07 0.05 5.0e-04 0.01 0.02 0.02 0.02 2.1e-02 7.7e-04 3.6e-03 3.3e-03
19 PL alternative TSS XM_039088778.1 0.04 0.03 1.1e-03 0.01 0.03 0.02 0.02 4.2e-02 7.6e-04 5.6e-03 9.4e-04
20 NAcc intron excision ratio chr1_86289906_86291110 0.03 0.03 6.3e-03 0.02 0.01 0.01 0.02 3.0e-03 6.9e-03 5.6e-02 4.4e-03
21 BLA isoform ratio NM_031648.2 0.05 0.04 7.5e-03 0.03 0.02 0.01 0.02 7.0e-03 3.0e-02 1.2e-01 3.3e-02
22 IL alternative TSS XM_039088778.1 0.12 0.09 6.6e-03 0.03 -0.01 -0.01 -0.01 8.1e-02 5.5e-01 8.5e-01 6.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.42.33.0-1.41.5-1.51.5-1.71.7-1.5-1.51.51.7-1.61.71.70.71.71.3-1.4-1.7-1.21.71.71.6
Area under the delay curve0.40.40.9-0.7-0.20.4-0.40.5-0.40.90.9-0.9-0.30.2-0.3-0.3-0.5-0.4-0.40.50.60.7-0.9-0.9-0.9
BMI with tail0.10.30.90.2-0.60.3-0.30.5-0.60.50.5-0.5-0.70.4-0.6-0.7-0.3-0.7-0.10.50.90.2-0.9-0.9-0.9
BMI without tail0.00.00.1-0.10.1-0.10.1-0.0-0.1-0.3-0.30.3-0.10.0-0.2-0.10.10.0-0.1-0.1-0.30.00.20.30.2
Body weight1.87.416.2-4.02.7-2.62.6-2.42.6-2.6-2.62.63.3-2.53.13.30.53.21.5-2.0-3.4-1.02.92.92.9
Weight adjusted by age0.20.30.7-0.40.4-0.90.9-0.70.7-0.6-0.60.60.4-0.20.30.4-0.20.50.1-0.3-0.60.20.50.50.5
Bone surface0.50.93.6-1.90.9-0.80.8-0.80.9-0.8-0.80.81.2-0.71.01.1-0.71.1-0.0-0.6-1.40.31.00.90.9
Bone volume0.91.64.6-2.11.2-1.11.1-1.21.4-1.1-1.11.11.6-1.11.41.5-0.31.50.4-0.9-1.7-0.11.41.31.3
Breakpoint value in progressive ratio session0.10.21.3-1.10.10.0-0.00.00.1-0.0-0.00.00.3-0.00.30.2-0.70.1-0.20.30.10.6-0.6-0.6-0.6
Number of licking bursts4.24.96.51.6-2.52.5-2.52.4-2.42.42.4-2.4-2.32.0-2.2-2.3-1.1-2.3-1.82.32.31.6-2.2-2.2-2.2
Context. condit. distance diff. score0.50.71.60.0-0.60.6-0.60.4-0.40.80.8-0.8-0.71.0-0.8-0.8-1.3-0.7-1.10.80.61.2-0.9-0.9-0.9
Locomotion velocity, session 10.10.10.30.60.1-0.30.3-0.00.1-0.2-0.20.20.2-0.00.20.20.10.20.4-0.5-0.3-0.60.60.50.5
Locomotion distance, session 10.40.54.1-1.2-0.40.3-0.30.3-0.10.30.3-0.30.10.7-0.1-0.0-2.0-0.0-1.10.6-0.51.4-0.1-0.0-0.0
Locomotion velocity, session 20.70.81.51.0-1.11.1-1.11.2-1.21.11.1-1.1-0.90.9-0.9-0.9-0.5-0.9-0.70.80.60.4-0.3-0.4-0.4
Locomotion distance, session 22.83.97.40.3-1.92.1-2.12.2-2.02.12.1-2.1-1.82.2-1.9-1.9-2.7-1.9-2.12.01.52.2-1.7-1.7-1.7
Locomotion velocity, session 30.50.61.00.2-0.70.8-0.80.9-0.90.90.9-0.9-0.80.9-0.9-0.8-1.0-0.7-1.00.80.20.9-0.3-0.3-0.3
Locomotion distance, session 31.21.36.0-2.2-0.60.9-0.91.0-0.71.01.0-1.0-0.20.9-0.4-0.3-2.5-0.3-1.81.3-0.22.3-0.7-0.6-0.6
Stereotopy head waving bouts, day 31.01.24.10.81.1-1.01.0-0.90.7-1.0-1.01.00.5-0.80.70.61.90.61.7-1.4-0.3-2.00.90.90.9
Stereotopy head waving duration, day 30.81.03.91.30.8-0.80.8-0.90.6-1.0-1.01.00.2-0.80.40.31.80.21.7-1.30.1-2.00.60.60.6
Locomotion velocity, session 70.40.41.6-0.9-0.50.5-0.50.6-0.30.70.7-0.7-0.00.5-0.1-0.1-1.3-0.2-0.80.90.11.2-0.4-0.5-0.5
Locomotion distance, session 70.10.21.0-0.8-0.10.3-0.30.20.00.00.0-0.00.30.30.10.2-1.00.2-0.60.3-0.60.70.30.30.3
Stereotopy head waving bouts, day 72.42.73.71.2-1.81.7-1.71.8-1.91.71.7-1.7-1.71.9-1.8-1.7-1.1-1.7-1.51.71.61.2-1.5-1.5-1.5
Stereotopy head waving duration, day 71.31.52.71.5-1.21.1-1.11.2-1.31.21.2-1.2-1.51.3-1.4-1.5-0.2-1.5-0.50.91.70.3-1.4-1.3-1.3
Locomotion velocity, session 84.14.96.22.3-2.12.1-2.12.2-2.22.42.4-2.4-2.52.2-2.5-2.5-1.8-2.5-1.91.92.31.8-2.3-2.3-2.3
Locomotion distance, session 83.65.310.20.6-2.22.4-2.42.2-2.02.32.3-2.3-2.12.7-2.3-2.2-3.2-2.2-2.82.41.62.9-2.1-2.1-2.1
Degree of sensitization distance0.70.72.11.10.7-0.50.5-0.70.6-0.9-0.90.90.5-0.70.60.61.50.61.0-0.9-0.4-1.40.80.80.8
Degree of sensitization stereotypy3.74.05.21.3-2.32.1-2.12.2-2.32.12.1-2.1-2.12.2-2.1-2.1-1.5-2.0-1.92.11.91.6-1.9-1.9-1.9
Conditioned locomotion0.50.61.60.7-0.60.8-0.80.6-0.70.60.6-0.6-0.90.7-0.8-0.90.1-0.9-0.20.41.30.1-1.1-1.1-1.1
Cocaine response after cond. corrected1.31.54.30.41.2-1.31.3-1.21.0-1.0-1.01.00.9-1.11.11.02.10.91.8-1.5-0.5-2.11.11.01.0
Cocaine response after cond. not corrected2.02.25.30.51.4-1.51.5-1.41.2-1.3-1.31.31.1-1.21.21.22.21.21.9-1.8-1.0-2.31.71.61.6
Cocaine response before conditioning0.30.41.9-0.40.1-0.20.2-0.10.2-0.3-0.30.30.50.10.20.5-0.70.6-0.6-0.1-1.40.41.21.11.1
Saline control response0.20.20.4-0.00.3-0.40.4-0.50.4-0.6-0.60.60.3-0.50.30.30.40.30.4-0.5-0.4-0.40.70.60.6
Bone: connectivity density0.20.30.5-0.50.4-0.40.4-0.50.6-0.5-0.50.50.6-0.50.60.6-0.00.60.3-0.4-0.7-0.20.70.70.6
Bone: cortical apparent density0.91.21.90.9-0.91.1-1.11.1-1.11.21.2-1.2-1.21.0-1.1-1.2-0.9-1.3-0.70.81.40.7-1.3-1.3-1.3
Bone: cortical area0.91.42.4-1.61.6-1.21.2-1.11.2-1.1-1.11.11.3-0.61.21.30.01.30.5-1.3-1.6-0.31.31.31.3
Bone: cortical porosity5.66.19.01.8-2.42.7-2.72.9-2.93.03.0-3.0-2.52.3-2.6-2.5-1.8-2.5-2.32.32.12.1-2.1-2.2-2.0
Bone: cortical porosity6.67.110.61.8-2.63.0-3.03.2-3.13.33.3-3.3-2.72.4-2.7-2.7-1.9-2.7-2.52.52.32.2-2.3-2.4-2.2
Bone: cortical thickness0.61.02.0-0.91.4-1.01.0-0.91.0-0.8-0.80.81.0-0.61.01.00.61.00.8-1.3-1.1-0.81.21.21.1
Bone: cortical thickness0.10.10.60.30.6-0.10.1-0.20.2-0.2-0.20.2-0.1-0.30.0-0.00.6-0.00.5-0.80.1-0.60.10.20.3
Bone: cortical tissue density1.11.52.31.0-1.01.2-1.21.2-1.21.41.4-1.4-1.31.1-1.2-1.3-1.0-1.4-0.70.91.50.8-1.5-1.4-1.5
Condit. Reinf. active minus inactive responses0.10.10.3-0.1-0.40.2-0.20.2-0.10.40.4-0.4-0.40.4-0.3-0.4-0.4-0.4-0.00.20.40.1-0.6-0.4-0.4
Condit. Reinf. active-inactive response ratio0.70.72.00.00.8-1.11.1-1.11.0-0.9-0.90.90.4-0.70.60.51.10.51.4-1.2-0.1-1.40.40.40.5
Condit. Reinf. active responses1.51.83.20.7-1.31.3-1.31.2-1.21.61.6-1.6-1.41.4-1.3-1.4-1.0-1.5-0.61.11.80.7-1.7-1.6-1.6
Condit. Reinf. inactive responses3.84.66.31.0-2.12.4-2.42.3-2.22.52.5-2.5-2.02.0-1.9-2.0-1.9-2.2-1.72.12.21.8-2.2-2.3-2.3
Incentive salience index mean0.40.40.7-0.1-0.60.6-0.60.6-0.50.80.8-0.8-0.60.7-0.5-0.6-0.8-0.7-0.30.50.70.5-0.9-0.7-0.7
Condit. Reinf. lever presses0.50.71.5-0.2-0.50.8-0.81.0-0.91.21.2-1.2-0.60.7-0.5-0.6-0.9-0.7-0.60.70.70.7-0.9-0.9-0.8
Condit. Reinf. active minus inactive responses0.30.41.4-1.20.5-0.40.4-0.40.6-0.4-0.40.40.7-0.30.50.6-0.80.6-0.2-0.3-1.00.40.70.70.7
Condit. Reinf. active-inactive response ratio0.00.00.1-0.00.2-0.10.1-0.10.10.20.2-0.2-0.10.2-0.1-0.1-0.3-0.1-0.2-0.2-0.10.20.00.00.0
Condit. Reinf. active responses0.50.72.5-1.60.4-0.40.4-0.40.7-0.5-0.50.51.0-0.30.81.0-1.20.9-0.50.0-1.40.70.90.90.9
Condit. Reinf. inactive responses0.30.42.0-1.3-0.30.4-0.40.4-0.20.10.1-0.10.50.10.30.5-1.40.4-1.00.9-0.81.20.20.20.2
Condit. Reinf. lever presses2.73.67.1-2.61.5-1.71.7-1.92.1-2.1-2.12.12.3-1.32.02.2-0.42.20.6-1.1-2.7-0.22.22.22.2
Condit. Reinf. lever reinforcers received0.40.62.6-1.60.2-0.10.1-0.20.4-0.2-0.20.20.80.00.50.7-1.60.7-0.90.3-1.31.20.70.70.7
Conditioned reinforcement - actives0.70.71.71.0-0.81.1-1.11.2-1.11.31.3-1.3-0.60.8-0.6-0.5-0.7-0.6-0.80.80.30.5-0.2-0.2-0.2
Conditioned reinforcement - inactives3.43.88.3-0.5-1.92.1-2.12.1-1.82.12.1-2.1-1.32.1-1.4-1.4-2.9-1.4-2.32.31.32.5-2.0-1.9-1.9
Conditioned locomotion3.64.37.21.8-1.82.3-2.32.4-2.42.72.7-2.7-1.91.7-1.8-2.0-1.2-2.1-1.41.72.31.2-2.2-2.1-2.1
Patch foraging indifference point 0 sec0.20.30.70.1-0.80.6-0.60.5-0.60.50.5-0.5-0.50.8-0.5-0.4-0.8-0.4-0.70.70.20.5-0.2-0.3-0.3
Patch foraging indifference point AUC0.10.10.60.8-0.00.1-0.10.1-0.20.30.3-0.3-0.1-0.30.0-0.00.7-0.10.5-0.10.3-0.7-0.1-0.0-0.0
Delay disc. indifference point, 0s delay1.31.43.1-1.1-0.70.8-0.81.0-0.71.41.4-1.4-0.60.7-0.5-0.7-1.7-0.8-0.91.21.21.5-1.8-1.7-1.7
Delay disc. indifference point, 16s delay0.30.40.9-0.7-0.10.4-0.40.6-0.50.90.9-0.9-0.20.1-0.1-0.2-0.5-0.3-0.30.50.70.6-0.9-0.9-0.9
Delay disc. indifference point, 2s delay0.30.43.3-1.8-0.00.2-0.20.30.00.30.3-0.30.40.00.40.3-1.20.2-0.40.5-0.00.9-0.6-0.5-0.5
Delay disc. indifference point, 24s delay0.30.22.2-1.50.5-0.30.3-0.20.40.20.2-0.20.7-0.50.60.6-0.50.5-0.00.1-0.30.5-0.1-0.2-0.2
Delay disc. indifference point, 4s delay1.51.52.70.3-1.21.3-1.31.5-1.41.71.7-1.7-1.01.2-1.1-1.1-1.2-1.1-1.21.31.01.1-1.2-1.2-1.2
Delay disc. indifference point, 8s delay0.10.10.3-0.3-0.10.2-0.20.2-0.20.50.5-0.5-0.10.1-0.2-0.1-0.0-0.1-0.40.30.00.4-0.1-0.2-0.2
Indifference point function ln k0.20.31.7-1.30.0-0.30.3-0.40.5-0.7-0.70.70.20.50.00.2-1.20.2-0.5-0.0-0.70.80.40.50.5
Indifference point function log k0.20.31.7-1.30.0-0.30.3-0.40.5-0.7-0.70.70.20.50.00.2-1.20.2-0.5-0.0-0.70.80.40.50.5
Patch foraging total patch changes 0 sec0.20.30.7-0.1-0.80.6-0.60.6-0.60.50.5-0.5-0.30.8-0.4-0.3-0.8-0.3-0.70.70.10.5-0.2-0.2-0.2
Patch foraging total patch changes 12 sec0.10.10.80.9-0.20.3-0.30.3-0.40.50.5-0.5-0.20.0-0.2-0.20.4-0.20.10.10.1-0.30.10.10.1
Patch foraging total patch changes 18 sec0.50.61.20.5-0.90.9-0.90.9-0.91.11.1-1.1-0.60.8-0.6-0.6-0.4-0.6-0.81.00.50.5-0.6-0.6-0.6
Patch foraging total patch changes 24 sec0.10.10.6-0.8-0.30.3-0.30.2-0.10.40.4-0.40.30.00.20.3-0.50.2-0.40.6-0.10.5-0.2-0.2-0.2
Patch foraging total patch changes 6 sec0.10.10.40.6-0.50.3-0.30.3-0.30.30.3-0.3-0.10.2-0.1-0.10.0-0.1-0.10.40.1-0.20.1-0.0-0.0
Patch foraging time to switch 0 sec0.40.64.91.60.70.0-0.00.1-0.3-0.0-0.00.0-0.2-0.90.1-0.12.2-0.11.1-0.80.6-1.50.0-0.0-0.0
Patch foraging water rate 0 sec0.81.23.70.4-1.41.1-1.11.0-0.80.90.9-0.9-1.11.6-1.1-1.1-1.9-1.2-1.11.10.91.2-1.0-1.0-1.0
Patch foraging water rate 12 sec0.71.15.0-0.2-1.51.1-1.10.9-0.70.50.5-0.5-0.41.5-0.7-0.4-2.2-0.4-2.01.5-0.61.80.10.10.1
Patch foraging water rate 18 sec0.40.51.20.8-1.00.9-0.90.7-0.60.40.4-0.4-0.71.0-0.8-0.7-1.1-0.7-0.90.80.30.7-0.4-0.3-0.3
Patch foraging water rate 24 sec3.54.913.5-0.2-2.72.2-2.21.9-1.61.81.8-1.8-1.72.6-2.0-1.8-3.7-1.8-3.02.91.13.3-1.9-1.8-1.8
Patch foraging water rate 6 sec0.81.27.1-1.2-1.31.1-1.10.8-0.50.60.6-0.6-0.21.2-0.5-0.3-2.7-0.4-1.81.5-0.22.1-0.5-0.5-0.5
Seeking ratio, delayed vs. immediate footshock0.50.51.9-1.4-0.40.7-0.70.7-0.40.60.6-0.60.00.4-0.1-0.0-1.4-0.1-1.00.9-0.01.4-0.7-0.6-0.5
Distance traveled before self-admin0.00.00.20.3-0.10.4-0.40.2-0.30.20.2-0.20.00.10.00.10.10.0-0.10.1-0.1-0.10.30.30.3
Distance traveled after self-admin0.40.52.0-1.30.4-0.20.2-0.30.5-0.2-0.20.20.9-0.40.60.8-0.40.9-0.60.1-1.40.70.90.90.9
Extensor digitorum longus weight1.03.97.9-1.62.4-2.12.1-2.32.2-2.1-2.12.11.7-2.12.01.71.91.62.8-2.6-0.7-2.41.01.01.1
Bone: elastic displacement0.20.20.60.10.2-0.30.3-0.10.1-0.3-0.30.30.4-0.30.40.50.70.50.5-0.3-0.5-0.80.60.80.8
Bone: elastic work1.21.62.6-1.61.3-1.21.2-1.01.1-1.1-1.11.11.6-1.21.61.60.71.61.0-1.0-1.5-0.81.31.41.4
Bone: endosteal estimation0.40.92.6-1.60.5-0.90.9-0.80.9-1.0-1.01.01.0-0.50.81.0-0.71.0-0.3-0.4-1.50.51.11.01.0
Bone: endosteal perimeter0.20.41.7-1.30.3-0.30.3-0.30.4-0.6-0.60.60.6-0.10.40.6-1.00.6-0.6-0.0-1.00.90.50.50.5
Epididymis fat weight0.10.10.9-0.8-0.10.2-0.20.3-0.10.10.1-0.10.20.40.10.2-1.00.2-0.50.3-0.40.70.20.20.2
Delta time in closed arm before/after self-admin2.82.74.9-2.21.7-1.91.9-1.92.0-1.6-1.61.61.8-1.71.71.70.81.81.2-1.3-1.7-0.71.51.41.4
Delta time in open arm before/after self-admin0.50.51.51.2-0.70.8-0.80.8-0.90.70.7-0.7-0.80.7-0.9-0.8-0.1-0.8-0.60.40.50.2-0.1-0.1-0.1
Diff in mean of infusions in LGA sessions1.21.32.81.0-1.11.1-1.10.9-0.90.90.9-0.9-1.31.1-1.2-1.3-0.5-1.3-0.81.01.50.8-1.6-1.6-1.7
Delay discount exponential model param0.20.20.50.70.1-0.20.2-0.40.3-0.7-0.70.70.2-0.10.20.20.40.20.4-0.4-0.4-0.60.70.70.7
Extinction: sum of active levers before priming4.14.15.5-2.12.2-2.12.1-2.12.1-2.2-2.22.22.3-2.12.32.31.32.31.8-1.8-1.9-1.51.71.71.7
Active lever presses in extinction session 66.36.17.5-1.42.7-2.62.6-2.52.4-2.1-2.12.12.6-2.72.62.62.52.62.5-2.6-2.5-2.52.62.62.6
Bone: final force0.71.14.1-2.01.3-1.21.2-1.11.2-0.9-0.90.91.2-0.91.21.2-0.11.20.5-0.8-1.20.00.90.80.8
Bone: final moment1.01.65.3-2.31.5-1.51.5-1.21.4-1.0-1.01.01.5-1.01.41.5-0.11.50.6-1.0-1.5-0.11.21.11.1
Food consumed during 24 hour testing period0.60.82.4-0.6-1.11.0-1.00.7-0.60.60.6-0.6-0.50.8-0.7-0.5-1.5-0.5-1.51.30.11.6-0.5-0.5-0.5
Glucose0.20.20.60.60.4-0.40.4-0.30.2-0.4-0.40.40.3-0.20.30.30.80.40.5-0.6-0.5-0.80.80.80.8
Heart weight0.30.42.9-0.6-0.70.2-0.20.4-0.20.60.6-0.6-0.20.8-0.3-0.2-1.7-0.3-0.80.80.21.2-0.6-0.6-0.6
Delay discount hyperbolic model param0.30.30.60.80.1-0.30.3-0.50.3-0.7-0.70.70.2-0.10.10.20.50.20.4-0.4-0.4-0.60.80.80.8
Intermittent access intake day 1-15 change1.31.32.7-1.71.1-1.21.2-1.21.3-1.2-1.21.21.5-1.01.41.40.21.40.6-0.7-1.3-0.31.01.01.0
Intermittent access intake escalation1.11.02.9-1.71.0-1.11.1-1.11.2-1.0-1.01.01.3-0.91.31.3-0.01.30.5-0.6-1.1-0.10.70.70.7
Intermittent access intake escalation 21.01.01.4-0.91.0-1.01.0-1.21.2-0.9-0.90.91.1-0.81.01.10.61.10.5-0.8-1.2-0.51.01.11.1
Intermitt. access day 1 inactive lever presses0.91.02.2-1.51.1-1.21.2-1.11.2-0.8-0.80.81.3-1.11.31.20.31.20.9-0.7-0.8-0.40.60.60.6
Intermitt. access day 15 inactive lever presses0.30.31.1-0.5-0.30.3-0.30.4-0.20.60.6-0.6-0.20.2-0.1-0.2-0.8-0.3-0.30.60.70.7-1.0-1.1-1.1
Intermitt. access escalation Index1.00.91.8-0.3-1.30.8-0.80.9-0.90.70.7-0.7-0.81.2-0.9-0.8-1.1-0.8-1.11.30.81.1-0.9-0.9-0.9
Intermittent access day 1 total infusions6.77.89.91.9-3.03.2-3.23.1-3.03.13.1-3.1-2.72.9-2.7-2.7-2.3-2.7-2.82.92.42.4-2.6-2.6-2.6
Intermittent access day 15 total infusions3.54.05.80.3-2.22.2-2.22.2-2.02.22.2-2.2-1.52.1-1.7-1.6-2.3-1.6-2.32.41.42.3-1.9-1.9-1.9
Intermittent access terminal intake (last 3 days)4.95.37.20.9-2.62.6-2.62.5-2.42.42.4-2.4-2.02.5-2.2-2.1-2.4-2.1-2.72.61.72.6-2.1-2.1-2.1
Intermittent access total infusions5.96.59.01.3-2.92.9-2.92.8-2.72.72.7-2.7-2.32.8-2.5-2.4-2.5-2.3-3.02.91.82.7-2.2-2.2-2.2
Intermittent access day 1 locomotion6.46.79.01.3-2.62.9-2.93.0-2.82.92.9-2.9-2.32.5-2.3-2.3-2.4-2.4-2.52.72.42.3-2.7-2.7-2.7
Intermittent access day 15 total locomotion3.53.86.40.3-2.32.1-2.12.1-1.82.12.1-2.1-1.32.1-1.5-1.4-2.5-1.5-2.22.41.42.1-2.0-2.0-2.0
Intermittent access total locomotion4.75.47.31.5-2.52.7-2.72.6-2.62.72.7-2.7-2.12.3-2.1-2.1-1.9-2.2-2.12.42.11.8-2.3-2.3-2.3
Intermittent access standard deviation0.40.42.9-1.70.1-0.20.2-0.20.40.20.2-0.20.7-0.10.50.7-0.90.7-0.80.5-1.11.20.30.40.4
Left kidney weight4.312.216.7-3.43.9-3.53.5-3.53.6-3.3-3.33.34.1-3.74.14.02.03.93.1-3.3-3.5-2.73.43.53.5
Right kidney weight5.214.720.7-4.24.0-3.83.8-3.63.9-3.7-3.73.74.6-4.04.44.51.84.43.0-3.3-4.2-2.43.94.04.0
Cocaine induced anxiety1.01.21.9-0.91.3-1.21.2-1.21.3-1.0-1.01.01.3-1.41.41.20.81.11.3-1.2-0.6-1.20.70.70.7
Post-drug Anxiety0.50.62.10.21.0-0.70.7-0.70.6-0.5-0.50.50.5-1.10.80.51.20.41.4-1.10.4-1.40.00.00.0
Baseline Anxiety1.51.62.31.0-1.11.4-1.41.4-1.51.51.5-1.5-1.51.2-1.4-1.4-0.4-1.4-0.81.01.40.7-1.3-1.3-1.3
Tail length2.57.614.8-3.12.7-2.52.5-2.52.7-2.8-2.82.83.2-2.42.93.20.83.31.2-2.1-3.9-1.03.43.43.4
Length with tail3.713.527.7-5.33.5-3.33.3-3.33.7-3.5-3.53.54.6-3.14.24.50.34.51.4-2.4-5.0-0.84.14.24.2
Length without tail2.45.216.0-4.01.9-2.02.0-2.02.4-1.9-1.91.93.1-1.92.93.0-0.52.90.9-1.1-3.0-0.22.22.32.3
Times rat made contact with spout0.40.51.00.10.2-0.50.5-0.90.8-1.0-1.01.00.5-0.60.40.50.80.50.6-0.6-0.7-0.80.90.90.9
Lifetime Intake3.84.36.21.3-2.42.3-2.32.3-2.22.22.2-2.2-2.02.4-2.1-2.0-2.1-1.9-2.52.31.42.2-1.7-1.7-1.7
Liver weight, left0.40.61.60.30.9-0.90.9-0.70.6-0.7-0.70.70.5-0.90.60.51.20.51.2-1.1-0.3-1.30.70.80.8
Liver weight, right0.10.10.50.30.00.1-0.10.3-0.30.10.1-0.10.1-0.60.20.20.30.10.4-0.2-0.2-0.60.70.60.7
Locomotor activity0.30.51.51.2-0.0-0.40.4-0.40.3-0.7-0.70.70.3-0.10.30.30.80.30.8-0.6-0.6-1.21.11.21.2
Locomotor testing distance0.10.21.51.2-0.5-0.00.00.0-0.1-0.3-0.30.3-0.10.4-0.2-0.10.2-0.00.1-0.0-0.4-0.50.80.80.8
Locomotor testing rearing0.61.02.71.6-1.40.9-0.91.0-1.10.70.7-0.7-1.21.5-1.3-1.2-0.9-1.1-0.90.90.60.6-0.3-0.3-0.3
Locomotion in novel chamber0.10.10.80.9-0.2-0.20.2-0.30.1-0.1-0.10.1-0.40.2-0.3-0.30.5-0.30.3-0.20.4-0.5-0.1-0.1-0.0
Locomotion in novel chamber post-restriction0.00.10.20.30.0-0.10.1-0.20.2-0.4-0.40.4-0.1-0.20.0-0.10.4-0.10.4-0.20.3-0.4-0.0-0.1-0.2
Fecal boli incidents, locomotor time 10.70.72.91.7-0.30.4-0.40.7-0.91.11.1-1.1-0.90.3-0.7-0.80.7-0.90.50.01.3-0.8-0.9-0.9-0.9
Change in fecal boli incidents, locomotor task1.91.82.8-0.21.5-1.41.4-1.41.4-1.5-1.51.51.1-1.51.31.21.71.21.6-1.7-0.9-1.61.11.11.1
Time >=10cm from walls, locomotor time 10.00.00.10.10.3-0.30.3-0.20.2-0.3-0.30.3-0.1-0.3-0.1-0.10.4-0.00.1-0.4-0.0-0.1-0.0-0.0-0.0
Bouts of movement, locomotor time 11.11.23.7-0.6-1.11.2-1.21.1-0.91.21.2-1.2-0.51.1-0.6-0.6-1.9-0.6-1.41.40.51.6-1.0-0.9-0.9
Total resting periods, locomotor time 10.80.92.4-0.4-0.91.0-1.01.1-0.91.11.1-1.1-0.40.9-0.5-0.5-1.5-0.5-1.11.20.41.2-0.9-0.8-0.8
Rest time, locomotor task time 10.30.41.11.00.20.1-0.10.2-0.20.60.6-0.6-0.3-0.2-0.0-0.30.8-0.40.9-0.41.1-1.0-0.8-0.8-0.8
Distance moved, locomotor task time 10.10.20.7-0.5-0.40.1-0.1-0.00.1-0.5-0.50.5-0.10.4-0.2-0.1-0.70.0-0.80.4-0.50.90.20.00.0
Vertical activity count, locomotor time 10.30.41.5-1.2-0.1-0.10.1-0.20.3-0.5-0.50.50.50.10.30.5-0.80.5-0.70.4-1.00.90.70.60.6
Time >=10cm from walls, locomotor time 21.31.42.01.4-1.01.0-1.01.3-1.31.31.3-1.3-1.41.0-1.3-1.4-0.4-1.4-0.70.81.30.5-1.3-1.3-1.3
Bouts of movement, locomotor time 20.50.51.30.3-1.00.9-0.90.7-0.60.60.6-0.6-0.61.0-0.8-0.6-0.9-0.5-1.21.00.01.0-0.1-0.1-0.1
Total resting periods, locomotor time 20.50.61.20.7-1.11.0-1.00.7-0.80.60.6-0.6-0.71.1-0.9-0.7-0.7-0.7-1.11.00.10.8-0.1-0.1-0.1
Rest time, locomotor task time 20.20.31.11.0-0.40.5-0.50.6-0.70.50.5-0.5-0.50.4-0.4-0.50.3-0.50.20.10.7-0.4-0.5-0.5-0.5
Distance moved, locomotor task time 20.40.51.6-0.3-0.70.6-0.60.6-0.50.40.4-0.4-0.50.7-0.7-0.6-1.1-0.5-1.10.80.11.3-0.4-0.5-0.5
Vertical activity count, locomotor time 20.20.21.5-1.20.00.1-0.10.10.10.10.1-0.10.3-0.00.10.2-0.90.2-0.70.4-0.41.00.10.00.0
Light reinforcement 10.81.42.20.3-1.31.4-1.41.5-1.41.21.2-1.2-1.11.4-1.2-1.1-1.3-1.1-1.51.30.61.3-0.9-0.8-0.8
Light reinforcement 20.81.12.40.8-0.81.0-1.00.8-0.90.70.7-0.7-1.41.1-1.2-1.4-0.9-1.4-0.40.41.50.5-1.3-1.3-1.3
Bone: marrow area0.40.92.4-1.60.6-1.01.0-0.91.0-1.0-1.01.01.1-0.60.81.0-0.61.1-0.2-0.5-1.50.41.21.11.1
Bone: maximum diameter0.71.32.2-1.51.5-1.21.2-1.11.2-1.2-1.21.21.3-0.91.21.30.11.30.5-1.2-1.4-0.31.01.11.1
Bone: maximum force1.01.76.3-2.51.6-1.41.4-1.31.5-1.1-1.11.11.6-1.01.51.5-0.41.50.4-0.9-1.50.11.21.11.1
Bone: maximum moment1.22.17.5-2.71.7-1.61.6-1.41.6-1.1-1.11.11.8-1.01.61.7-0.41.70.5-1.0-1.80.11.41.31.3
Mean time between licks in bursts0.40.52.1-0.0-0.90.6-0.60.5-0.40.40.4-0.4-0.71.0-0.8-0.8-1.4-0.7-0.90.80.51.1-0.7-0.7-0.7
Mean num. licks in bursts4.35.26.5-1.42.3-2.52.5-2.62.6-2.6-2.62.62.3-2.02.22.31.32.31.9-2.3-2.3-1.82.42.42.4
Cd content in liver0.20.20.70.10.4-0.30.3-0.20.1-0.0-0.00.00.4-0.60.30.40.80.50.2-0.4-0.6-0.40.60.60.6
Co content in liver0.10.10.70.60.2-0.20.2-0.30.2-0.2-0.20.2-0.1-0.30.1-0.10.8-0.10.7-0.30.6-0.6-0.3-0.3-0.3
Cu content in liver0.30.41.3-1.10.7-0.50.5-0.50.7-0.6-0.60.60.8-1.10.90.80.30.70.5-0.5-0.5-0.20.30.30.3
Fe content in liver0.10.10.20.4-0.30.3-0.30.2-0.20.40.4-0.4-0.40.2-0.4-0.4-0.1-0.3-0.30.20.30.3-0.4-0.4-0.4
K content in liver0.10.10.20.2-0.40.4-0.40.4-0.40.30.3-0.3-0.3-0.1-0.3-0.30.0-0.3-0.20.30.30.2-0.3-0.3-0.3
Mg content in liver0.10.10.40.6-0.40.1-0.10.2-0.20.10.1-0.1-0.4-0.1-0.2-0.40.4-0.40.40.00.7-0.4-0.4-0.4-0.4
Mn content in liver0.20.32.71.6-0.10.2-0.20.2-0.40.00.0-0.0-0.60.1-0.5-0.51.0-0.50.3-0.40.3-0.80.10.10.2
Na content in liver0.20.20.8-0.8-0.10.5-0.50.6-0.40.30.3-0.30.2-0.00.00.2-0.80.1-0.80.4-0.40.9-0.0-0.0-0.0
Rb content in liver0.30.41.8-0.4-0.50.1-0.10.1-0.00.50.5-0.5-0.5-0.2-0.3-0.6-0.0-0.6-0.00.51.20.5-1.3-1.3-1.3
Se content in liver1.31.65.62.4-0.71.0-1.01.0-1.21.01.0-1.0-1.70.8-1.4-1.60.4-1.70.30.12.1-0.5-1.4-1.4-1.4
Sr content in liver0.20.22.01.4-0.30.3-0.30.3-0.40.50.5-0.5-0.50.7-0.5-0.50.3-0.5-0.10.00.3-0.30.00.00.0
Zn content in liver0.10.10.4-0.30.4-0.20.2-0.20.30.10.1-0.10.1-0.30.30.10.3-0.00.6-0.30.5-0.4-0.4-0.4-0.4
Bone: minimum diameter0.30.53.4-1.90.4-0.20.2-0.10.4-0.2-0.20.20.8-0.10.50.7-1.20.8-0.80.1-1.11.10.60.50.4
Time in familiar zone, hab. session 14.74.46.2-1.62.2-2.22.2-2.42.5-2.3-2.32.32.2-2.42.32.11.32.12.2-2.2-1.7-1.81.81.81.8
Time in novel zone, hab. session 15.95.87.62.2-2.62.6-2.62.5-2.72.42.4-2.4-2.62.8-2.7-2.6-1.5-2.5-2.42.42.12.0-2.1-2.1-2.1
Total zone transitions, hab. session 10.71.03.0-0.3-1.10.8-0.80.9-0.81.11.1-1.1-0.81.2-0.9-0.8-1.7-0.8-1.31.20.41.5-0.8-0.7-0.7
Total locomotion distance, hab. session 10.50.72.3-0.0-1.00.8-0.80.8-0.80.90.9-0.9-0.51.0-0.8-0.5-1.2-0.4-1.51.0-0.51.30.10.20.2
Locomotion velocity, hab. session 10.20.31.10.2-0.70.5-0.50.5-0.60.60.6-0.6-0.30.7-0.5-0.3-0.6-0.2-1.00.6-0.60.70.40.40.4
Time in familiar zone, hab. session 22.72.84.2-0.31.4-1.81.8-2.11.9-2.0-2.02.01.6-1.81.61.61.91.61.7-1.7-1.3-1.71.41.41.4
Time in novel zone, hab. session 21.21.22.20.4-1.01.2-1.21.5-1.41.41.4-1.4-1.11.1-1.1-1.1-1.1-1.1-1.11.00.81.0-0.8-0.8-0.8
Total zone transitions, hab. session 23.54.66.71.9-2.52.1-2.12.1-2.12.02.0-2.0-2.52.6-2.5-2.5-2.1-2.4-2.12.01.81.9-1.8-1.8-1.8
Total locomotion distance, hab. session 22.33.14.91.4-2.11.8-1.81.7-1.71.61.6-1.6-1.92.2-2.1-1.9-1.8-1.8-2.21.91.11.9-1.3-1.3-1.3
Locomotion velocity, hab. session 21.82.44.11.3-1.91.6-1.61.5-1.51.31.3-1.3-1.72.0-1.9-1.7-1.6-1.6-1.91.61.01.6-1.2-1.1-1.1
Novel to familiar place preference ratio0.00.10.3-0.0-0.30.1-0.10.2-0.20.10.1-0.1-0.00.2-0.1-0.1-0.3-0.1-0.30.50.10.4-0.2-0.3-0.3
Novelty place preference0.20.20.50.2-0.50.3-0.30.5-0.40.30.3-0.3-0.20.4-0.3-0.3-0.5-0.3-0.60.70.20.6-0.4-0.4-0.4
Time in novel zone, NPP test0.30.30.80.3-0.70.5-0.50.6-0.60.50.5-0.5-0.40.6-0.5-0.5-0.6-0.5-0.70.90.40.8-0.5-0.5-0.5
Total zone transitions, NPP test0.20.21.3-0.4-0.50.3-0.30.4-0.30.50.5-0.5-0.30.7-0.4-0.3-1.1-0.3-0.70.4-0.10.8-0.1-0.0-0.0
Total locomotion distance, NPP test0.50.72.9-1.10.2-0.40.4-0.40.5-0.5-0.50.50.8-0.10.50.8-0.40.9-0.5-0.1-1.70.41.31.41.4
Locomotion velocity, NPP test0.50.73.1-1.00.4-0.60.6-0.60.6-0.7-0.70.70.9-0.30.60.9-0.21.0-0.4-0.3-1.70.21.41.51.5
Intraocular pressure0.30.40.70.4-0.90.3-0.30.2-0.40.20.2-0.2-0.80.8-0.8-0.8-0.3-0.6-0.70.80.70.6-0.7-0.8-0.9
Delta distance traveled before/after self-admin1.01.04.2-2.00.8-1.01.0-1.01.1-0.8-0.80.81.2-0.81.01.2-0.31.3-0.1-0.3-1.50.50.90.90.9
Delta ambulatory time before/after self-admin0.91.04.8-2.20.7-0.90.9-0.91.1-0.8-0.80.81.3-0.71.01.2-0.51.3-0.3-0.2-1.60.60.90.90.9
Parametrial fat weight3.77.212.1-0.62.8-2.72.7-2.72.5-2.8-2.82.82.2-2.82.52.33.22.33.4-3.2-1.8-3.52.72.72.6
Pavlov. Cond. lever latency1.41.82.7-0.91.3-1.61.6-1.61.6-1.6-1.61.61.4-1.61.61.41.31.31.6-1.2-0.7-1.30.80.70.7
Pavlov. Cond. magazine entry latency2.02.55.11.7-2.11.9-1.91.7-1.81.31.3-1.3-1.72.2-2.0-1.7-1.6-1.6-2.21.60.31.6-0.2-0.2-0.2
Pavlov. Cond. change in total contacts4.85.17.81.1-2.62.6-2.62.5-2.52.52.5-2.5-2.22.6-2.4-2.2-2.5-2.1-2.82.51.22.5-1.5-1.5-1.5
Pavlov. Cond. index score2.32.94.91.7-2.12.1-2.11.9-2.01.61.6-1.6-1.92.2-2.1-1.8-1.6-1.8-2.21.60.61.6-0.6-0.6-0.6
Pavlov. Cond. latency score2.22.84.61.4-1.92.0-2.01.9-1.91.61.6-1.6-1.82.1-2.0-1.7-1.7-1.7-2.11.60.71.7-0.7-0.7-0.7
Pavlov. Cond. lever contacts1.11.22.30.5-1.21.4-1.41.3-1.31.21.2-1.2-1.11.3-1.3-1.1-1.1-1.1-1.51.10.41.3-0.5-0.5-0.5
Pavlov. Cond. magazine entry number2.53.15.7-1.52.3-2.12.1-2.02.0-1.5-1.51.51.9-2.42.21.91.81.82.4-1.9-0.5-1.80.50.50.5
Pavlov. Cond. intertrial magazine entries0.10.10.50.30.20.1-0.10.1-0.00.20.2-0.20.00.00.2-0.0-0.2-0.20.6-0.10.7-0.4-0.5-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.3.03.76.21.8-2.32.3-2.32.2-2.21.81.8-1.8-2.12.5-2.4-2.1-1.8-2.0-2.51.90.81.9-0.8-0.8-0.8
Pavlov. Cond. response bias1.01.22.51.1-1.61.3-1.31.2-1.30.90.9-0.9-1.21.5-1.4-1.1-1.0-1.0-1.61.1-0.01.00.10.10.1
Pavlov. Cond. lever latency1.21.66.62.6-0.80.9-0.91.0-1.21.11.1-1.1-1.60.9-1.4-1.60.8-1.5-0.00.21.8-0.4-1.2-1.2-1.2
Pavlov. Cond. magazine entry latency0.40.41.4-1.20.3-0.40.4-0.40.6-0.5-0.50.50.9-0.60.80.9-0.50.8-0.1-0.1-1.00.20.70.70.7
Pavlov. Cond. change in total contacts1.31.88.6-2.90.9-0.90.9-1.01.3-1.2-1.21.21.8-1.01.51.7-1.01.7-0.3-0.1-2.00.81.11.11.1
Pavlov. Cond. index score0.91.25.1-2.20.6-0.70.7-0.71.0-1.0-1.01.01.5-0.91.21.4-0.81.4-0.2-0.1-1.70.51.21.21.2
Pavlov. Cond. latency score0.81.04.3-2.10.5-0.60.6-0.60.8-0.8-0.80.81.3-0.81.11.3-0.81.2-0.2-0.1-1.50.51.01.01.0
Pavlov. Cond. lever contacts0.91.26.1-2.50.6-0.70.7-0.81.1-0.9-0.90.91.5-0.81.31.4-0.91.4-0.2-0.0-1.60.61.11.01.0
Pavlov. Cond. magazine entry number1.11.34.62.1-0.80.8-0.80.9-1.11.11.1-1.1-1.51.1-1.2-1.40.7-1.40.10.41.8-0.4-1.2-1.3-1.3
Pavlov. Cond. intertrial magazine entries0.20.21.01.00.10.1-0.10.0-0.20.30.3-0.3-0.40.3-0.2-0.40.7-0.40.5-0.20.9-0.6-0.5-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.11.44.8-2.20.8-0.80.8-0.91.1-1.1-1.11.11.5-1.01.31.5-0.71.5-0.1-0.3-1.80.41.31.31.3
Pavlov. Cond. response bias0.91.36.8-2.60.5-0.60.6-0.71.0-0.8-0.80.81.5-0.61.21.4-1.31.3-0.40.1-1.70.91.01.01.0
Time in closed arm before self-admin3.43.95.32.1-1.92.1-2.12.2-2.32.32.3-2.3-2.01.9-1.9-2.0-1.2-2.0-1.41.82.11.2-2.0-1.9-1.9
Time in closed arm after self-admin0.10.10.4-0.20.0-0.20.20.00.00.40.4-0.4-0.3-0.0-0.2-0.3-0.1-0.3-0.10.20.40.5-0.6-0.6-0.5
Time in open arm before self-admin3.43.76.1-1.81.6-1.81.8-2.02.0-2.2-2.22.22.2-1.72.02.20.92.21.1-1.5-2.5-1.12.32.22.2
Time in open arm after self-admin0.60.62.1-0.50.3-0.30.3-0.40.4-0.8-0.80.80.9-0.40.60.90.10.9-0.1-0.4-1.4-0.31.51.41.4
Bone: periosteal estimation0.91.84.1-2.01.4-1.41.4-1.21.4-1.4-1.41.41.5-0.81.31.4-0.41.50.2-1.1-1.90.11.51.51.4
Bone: periosteal perimeter0.61.02.2-0.91.3-0.90.9-0.90.9-1.1-1.11.11.0-0.60.81.00.01.10.2-1.1-1.5-0.21.21.21.2
Bone: post-yield work0.40.52.9-1.4-0.50.2-0.20.00.10.30.3-0.30.10.5-0.10.1-1.70.1-1.11.0-0.31.5-0.3-0.3-0.4
Progressive ratio test 1 active lever presses1.92.03.9-0.3-1.71.6-1.61.6-1.41.71.7-1.7-0.71.5-0.8-0.7-2.0-0.8-1.81.90.61.7-1.1-1.1-1.1
Progressive ratio test 1 breakpoint1.01.02.5-0.5-1.21.2-1.21.2-1.01.31.3-1.3-0.31.0-0.4-0.3-1.6-0.4-1.41.50.31.3-0.7-0.7-0.7
Progressive ratio test 1 inactive lever presses2.52.75.7-0.4-1.81.5-1.51.6-1.31.91.9-1.9-1.21.5-1.3-1.3-2.2-1.3-2.02.11.02.4-1.6-1.6-1.6
Progressive ratio test 2 active lever presses2.32.54.10.4-1.81.9-1.91.8-1.61.81.8-1.8-1.01.7-1.2-1.1-2.0-1.1-2.01.90.81.8-1.2-1.2-1.2
Progressive ratio test 2 breakpoint2.12.43.70.6-1.81.9-1.91.8-1.61.81.8-1.8-1.11.7-1.2-1.1-1.9-1.1-1.91.90.71.7-1.1-1.1-1.1
Progressive ratio test 2 inactive lever presses4.04.69.1-0.8-2.22.0-2.02.0-1.72.12.1-2.1-1.52.2-1.6-1.6-3.0-1.7-2.42.61.72.9-2.5-2.5-2.5
Incentive Sensitization - Responses0.70.71.70.4-0.91.0-1.00.8-0.70.90.9-0.9-0.61.1-0.7-0.6-1.3-0.6-1.10.90.41.0-0.7-0.7-0.7
Incentive Sensitization - Breakpoint0.50.51.40.3-0.80.8-0.80.6-0.60.70.7-0.7-0.50.9-0.6-0.5-1.2-0.5-0.90.80.30.9-0.6-0.6-0.6
Sum of active levers in priming session hrs 5-60.20.20.4-0.60.6-0.60.6-0.50.6-0.5-0.50.50.6-0.60.60.50.30.50.5-0.5-0.4-0.30.10.20.2
Progressive ratio0.40.40.70.7-0.70.8-0.80.8-0.80.90.9-0.9-0.60.7-0.6-0.5-0.4-0.5-0.70.70.20.4-0.2-0.1-0.1
Food seeking constrained by brief footshock0.40.51.8-1.00.6-0.30.3-0.30.4-0.3-0.30.30.9-0.40.70.9-0.30.9-0.3-0.3-1.40.31.01.01.1
Seeking ratio, punishment vs. effort0.10.10.9-0.90.2-0.20.2-0.10.3-0.1-0.10.10.4-0.10.30.3-0.60.3-0.20.0-0.30.50.10.00.0
Retroperitoneal fat weight0.20.63.01.50.5-0.50.5-0.30.1-0.5-0.50.50.1-0.50.30.21.50.11.4-1.00.2-1.70.60.60.6
Reaction time number correct0.10.20.4-0.60.3-0.20.2-0.50.5-0.6-0.60.60.4-0.20.40.4-0.40.30.3-0.4-0.3-0.10.30.30.3
Reaction time mean minus median0.40.50.9-0.50.9-0.80.8-0.60.6-0.6-0.60.60.8-0.80.80.80.80.80.5-0.6-0.8-0.50.70.70.7
Reaction time mean minus median AUC1.21.51.9-1.01.4-1.21.2-1.11.1-1.2-1.21.21.4-1.41.41.41.11.41.0-1.1-1.3-1.01.21.21.2
Reaction time num false alarms0.30.51.11.1-0.30.6-0.60.5-0.60.70.7-0.7-0.80.1-0.7-0.80.6-0.8-0.20.31.00.0-0.9-0.9-0.9
Reaction time num false alarms AUC0.50.62.31.5-0.50.7-0.70.6-0.80.70.7-0.7-1.00.3-0.9-1.00.6-0.9-0.30.41.10.0-1.0-0.9-0.9
Reaction time trials correct on left0.10.20.4-0.60.3-0.20.2-0.50.5-0.6-0.60.60.4-0.20.40.4-0.40.30.3-0.4-0.3-0.10.30.30.3
Reaction time trials on left0.10.20.4-0.60.4-0.30.3-0.50.6-0.6-0.60.60.4-0.20.50.4-0.40.40.4-0.5-0.4-0.20.30.40.4
Reaction time mean0.10.10.4-0.3-0.0-0.20.20.0-0.0-0.1-0.10.10.20.10.00.2-0.20.3-0.40.2-0.60.40.30.40.4
Reaction time mean AUC0.00.10.3-0.0-0.1-0.20.20.0-0.1-0.1-0.10.10.10.1-0.10.1-0.10.2-0.40.2-0.60.20.30.40.4
Median of all reaction times0.10.10.60.0-0.50.2-0.20.4-0.40.20.2-0.2-0.20.5-0.4-0.2-0.5-0.1-0.80.5-0.30.70.00.10.1
Reaction time omissions0.20.20.50.20.1-0.70.7-0.70.5-0.6-0.60.60.2-0.10.10.20.40.30.3-0.4-0.5-0.40.60.70.7
Reaction time false alarm rate0.60.82.11.4-0.60.7-0.70.8-1.00.90.9-0.9-1.10.5-1.0-1.00.6-1.0-0.50.61.10.2-1.0-1.0-1.0
Reaction time premature initiation rate1.21.73.10.8-1.31.6-1.61.8-1.71.41.4-1.4-1.11.2-1.1-1.1-1.0-1.1-1.41.41.01.2-1.1-1.1-1.1
Reaction time premature initiations0.81.12.00.4-1.01.4-1.41.4-1.31.11.1-1.1-0.81.0-0.8-0.8-1.1-0.9-1.11.10.81.0-0.9-0.9-0.9
Std. dev. reaction times0.20.20.7-0.70.4-0.50.5-0.40.4-0.5-0.50.50.6-0.30.50.60.10.7-0.1-0.1-0.80.10.50.60.6
Reaction time trials completed0.10.20.4-0.60.4-0.30.3-0.50.6-0.6-0.60.60.4-0.20.50.4-0.40.40.4-0.5-0.4-0.20.30.40.4
Reaction time trials AUC0.30.40.8-0.50.6-0.60.6-0.80.8-0.9-0.90.90.6-0.50.70.6-0.00.50.7-0.8-0.5-0.50.50.60.6
Run reversals in cocaine runway, females0.20.20.9-0.90.4-0.30.3-0.30.4-0.4-0.40.40.6-0.20.50.5-0.60.5-0.1-0.1-0.50.50.00.10.1
Run reversals in cocaine runway, males2.72.64.80.91.4-1.81.8-1.91.7-1.2-1.21.21.1-1.41.21.22.11.31.9-1.9-1.3-2.21.91.91.9
Latency to leave start box in cocaine runway0.20.21.3-1.20.20.2-0.20.3-0.20.50.5-0.50.2-0.30.30.2-0.50.1-0.10.20.30.4-0.6-0.6-0.6
Latency to leave start box in cocaine runway, F0.30.31.0-1.0-0.20.2-0.20.3-0.20.70.7-0.7-0.10.1-0.1-0.2-0.9-0.3-0.30.50.60.8-0.9-0.9-0.9
Latency to leave start box in cocaine runway, M0.20.20.8-0.20.70.0-0.0-0.10.0-0.2-0.20.20.4-0.70.40.40.90.40.3-0.5-0.2-0.50.30.30.3
Std. dev. time between licks in bursts3.33.96.00.6-2.22.1-2.12.0-1.92.02.0-2.0-1.82.4-2.0-1.9-2.3-1.8-2.42.31.32.4-1.7-1.7-1.7
Total sessions with >9 infusions1.21.32.61.6-1.41.3-1.31.3-1.31.21.2-1.2-1.31.3-1.4-1.2-0.8-1.2-1.21.10.70.9-0.6-0.6-0.6
Short access day 1 total inactive lever presses3.13.55.7-0.3-1.62.0-2.02.0-1.72.12.1-2.1-1.31.5-1.3-1.4-2.4-1.5-1.82.11.72.2-2.3-2.2-2.2
Short access day 10 total inactive lever presses0.20.21.8-1.30.3-0.40.4-0.40.5-0.2-0.20.20.4-0.40.50.4-0.60.30.10.1-0.10.5-0.3-0.2-0.2
Short access day 1 total infusions0.90.92.50.4-1.10.9-0.90.9-0.80.90.9-0.9-0.91.3-1.0-0.9-1.6-0.9-1.41.10.31.4-0.5-0.5-0.5
Short access day 10 total infusions0.80.91.21.1-1.01.1-1.11.0-1.01.11.1-1.1-1.00.9-1.0-1.0-0.5-0.9-1.10.90.70.9-0.7-0.7-0.7
Short access total infusions1.01.11.81.3-1.31.2-1.21.1-1.11.11.1-1.1-1.11.2-1.2-1.1-0.9-1.0-1.21.00.60.9-0.6-0.5-0.5
Short access day 1 locomotion0.30.30.50.3-0.40.6-0.60.7-0.60.60.6-0.6-0.50.4-0.5-0.6-0.3-0.5-0.40.40.50.5-0.5-0.5-0.5
Short access day 10 total locomotion1.61.83.50.1-1.41.6-1.61.5-1.41.41.4-1.4-0.91.5-1.1-1.0-1.6-1.0-1.91.70.51.7-1.0-1.0-1.0
Short access total locomotion1.81.92.61.3-1.41.6-1.61.6-1.61.61.6-1.6-1.41.3-1.5-1.4-0.8-1.4-1.21.21.21.0-1.2-1.1-1.1
One hour access (0.3 mA shock)3.33.89.30.0-2.42.3-2.32.2-1.91.91.9-1.9-1.22.5-1.6-1.2-3.0-1.2-3.02.60.42.8-1.1-1.0-1.0
Compulsive drug intake0.10.10.40.1-0.3-0.00.0-0.00.10.30.3-0.30.10.20.00.1-0.60.1-0.20.2-0.20.20.20.20.2
One hour access (shock baseline)2.52.85.00.4-1.92.0-2.02.0-1.81.61.6-1.6-1.42.0-1.6-1.4-2.0-1.4-2.22.00.92.1-1.4-1.3-1.3
Social response proportion0.90.92.1-1.41.3-1.21.2-1.31.4-1.0-1.01.01.0-1.21.11.00.40.90.8-0.9-0.5-0.20.30.30.3
Social responses0.20.20.7-0.60.6-0.60.6-0.50.6-0.3-0.30.30.5-0.80.60.50.40.40.7-0.5-0.0-0.3-0.10.00.0
Social time0.50.64.2-2.10.2-0.40.4-0.50.8-0.8-0.80.80.8-0.30.60.7-1.30.7-0.60.2-0.91.20.20.30.3
Soleus weight0.10.20.7-0.10.6-0.50.5-0.40.4-0.5-0.50.50.3-0.20.40.30.40.30.8-0.80.0-0.80.20.20.2
Bone: stiffness0.71.14.0-2.01.4-1.21.2-1.41.5-1.0-1.01.01.1-0.81.11.0-0.31.00.4-0.9-0.90.20.70.50.4
Tibialis anterior weight1.34.46.9-1.52.4-2.32.3-2.32.2-2.2-2.22.21.9-2.12.11.92.11.92.6-2.6-1.4-2.41.61.71.8
Time to tail flick, vehicle, before self-admin0.80.81.20.9-1.11.0-1.01.0-1.00.70.7-0.7-0.91.1-0.9-0.9-0.8-1.0-0.60.91.00.5-0.9-0.8-0.8
Time to tail flick, vehicle, after self-admin0.20.21.21.1-0.30.4-0.40.5-0.60.50.5-0.5-0.70.3-0.7-0.60.5-0.5-0.50.20.20.1-0.1-0.0-0.0
Time to tail flick, test, before self-admin3.53.56.9-0.2-2.02.0-2.02.0-1.81.91.9-1.9-1.42.0-1.6-1.5-2.6-1.6-2.22.31.32.4-1.8-1.7-1.7
Time to tail flick, test, after self-admin0.20.20.60.0-0.70.5-0.50.5-0.4-0.1-0.10.1-0.30.7-0.4-0.3-0.8-0.3-0.70.60.20.6-0.3-0.3-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.30.40.00.1-0.10.1-0.20.20.2-0.2-0.1-0.0-0.2-0.00.50.1-0.40.1-0.50.10.50.40.4
Delta time to tail flick, test, before/after SA1.31.22.91.00.9-0.90.9-0.90.7-1.3-1.31.30.6-0.90.60.71.70.71.3-1.4-0.7-1.61.21.21.2
Tibia length1.64.414.6-3.82.0-2.12.1-2.02.3-2.1-2.12.12.5-1.52.32.4-0.72.40.6-1.2-2.70.12.02.02.0
Ambulatory time before self-admin0.10.10.30.5-0.20.5-0.50.3-0.40.30.3-0.3-0.10.1-0.1-0.10.2-0.2-0.00.10.2-0.2-0.0-0.0-0.0
Ambulatory time after self-admin0.91.05.1-2.30.8-0.60.6-0.81.0-0.5-0.50.51.4-0.81.21.3-0.51.3-0.3-0.1-1.60.70.80.90.9
Bone: tissue strength0.40.43.3-1.80.4-0.60.6-0.30.50.10.1-0.10.8-0.10.70.7-0.90.7-0.30.4-0.60.80.10.00.1
Total heroin consumption0.20.20.4-0.6-0.30.4-0.40.5-0.40.40.4-0.4-0.10.2-0.1-0.1-0.6-0.2-0.50.50.20.6-0.7-0.7-0.7
Bone: trabecular number0.71.23.8-1.90.9-0.90.9-1.11.3-1.0-1.01.01.4-1.01.31.3-0.41.30.4-0.5-1.3-0.11.01.01.0
Bone: trabecular spacing0.20.31.40.90.3-0.30.3-0.1-0.0-0.2-0.20.20.20.10.20.31.20.40.3-0.4-0.5-0.80.80.70.8
Bone: trabecular thickness0.20.21.3-1.10.5-0.40.4-0.30.4-0.3-0.30.30.5-0.60.60.5-0.30.50.4-0.4-0.3-0.10.10.20.2
Bone: trabecular tissue density0.81.24.01.81.0-0.90.9-0.80.5-0.8-0.80.80.3-0.90.40.42.00.41.5-1.6-0.4-2.01.01.01.1
Water consumed over 24 hours0.30.41.7-1.30.4-0.30.3-0.60.8-0.7-0.70.70.7-0.70.60.7-0.30.60.1-0.3-0.80.20.50.50.5
Number of responses in last shaping day3.63.86.70.3-2.22.1-2.12.0-1.82.12.1-2.1-1.62.3-1.8-1.7-2.6-1.7-2.42.31.12.4-1.5-1.6-1.6