Fndc3a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr15_47755611_47759381 0.02 0.02 7.3e-03 0 0.01 0 0 1.5e-01 4.9e-02 2.0e-01 1.3e-01
2 Adipose mRNA stability Fndc3a 0.04 0.03 4.8e-04 0.03 0.02 0.03 0.03 7.2e-04 1.6e-03 5.3e-04 5.9e-04
3 Adipose alternative TSS XM_006252300.4 0.03 0.02 8.3e-03 0.01 0 -0 0 4.9e-02 1.6e-01 6.0e-01 2.1e-01
4 Liver isoform ratio NM_001412039.1 0.02 0.02 9.2e-03 0.02 0 0.01 0.01 2.0e-03 1.2e-01 3.6e-02 4.6e-02
5 Adipose isoform ratio XM_006252300.4 0.03 0.02 5.5e-03 0.01 0 -0 0 2.3e-02 7.8e-02 5.4e-01 1.5e-01
6 Liver alternative TSS XM_006252300.4 0.04 0.03 3.9e-04 0.03 0.02 0.03 0.02 3.5e-04 3.4e-03 6.2e-04 2.7e-03
7 Liver isoform ratio XM_006252300.4 0.03 0.02 1.4e-03 0.03 0.01 0.02 0 4.3e-04 1.9e-02 4.5e-03 1.3e-01
8 NAcc gene expression Fndc3a 0.11 0.06 9.2e-11 0.07 0.09 0.09 0.09 1.8e-08 1.5e-10 9.0e-11 2.1e-10
9 Liver mRNA stability Fndc3a 0.02 0.02 8.4e-03 0 0 -0 0 1.4e-01 1.6e-01 3.9e-01 1.6e-01
10 Liver alternative TSS XM_006252298.4 0.02 0.02 7.7e-03 0.01 0.01 0 0.01 1.6e-02 3.4e-02 1.8e-01 6.9e-02
11 Liver alternative TSS XM_006252298.4 0.02 0.02 9.6e-03 0.02 0.01 0 0.01 6.2e-03 3.0e-02 1.1e-01 1.6e-02
12 Brain gene expression Fndc3a 0.14 0.07 4.3e-12 0.13 0.14 0.14 0.14 2.8e-12 1.2e-12 7.6e-13 9.2e-13
13 Adipose isoform ratio NM_001412039.1 0.03 0.02 1.9e-03 0.01 0.02 0.01 0.02 5.7e-02 1.6e-03 7.1e-03 5.2e-03
14 BLA isoform ratio XM_006252298.4 0.2 0.13 6.3e-03 0 0.03 0.03 0.01 2.3e-01 1.0e-02 1.1e-02 6.4e-02
15 BLA gene expression Fndc3a 0.27 0.12 8.8e-10 0.11 0.16 0.16 0.16 1.4e-06 1.2e-08 7.0e-09 1.1e-08
16 BLA alternative TSS XM_006252298.4 0.28 0.15 7.1e-04 0.01 0.06 0.06 0.04 9.9e-02 2.4e-04 6.4e-04 2.1e-03
17 BLA alternative TSS XM_006252298.4 0.29 0.15 6.6e-04 0.02 0.07 0.05 0.05 4.6e-02 1.9e-04 7.5e-04 1.2e-03
18 Adipose alternative TSS NM_001412039.1 0.03 0.02 2.2e-03 0.01 0.02 0.01 0.01 3.8e-02 2.3e-03 1.2e-02 9.5e-03
19 Adipose alternative TSS NM_001412039.1 0.03 0.02 2.4e-03 0.01 0.02 0.01 0.01 5.4e-02 3.4e-03 2.2e-02 9.9e-03
20 Liver alternative TSS XM_006252300.4 0.05 0.03 1.8e-05 0.04 0.03 0.04 0.03 1.5e-05 1.5e-04 8.9e-06 9.4e-05
21 PL gene expression Fndc3a 0.1 0.05 3.8e-09 0.08 0.08 0.08 0.08 5.9e-09 2.9e-09 3.9e-09 8.2e-09
22 Adipose gene expression Fndc3a 0.19 0.1 6.1e-11 0.06 0.09 0.08 0.07 1.7e-07 6.8e-10 2.3e-09 1.0e-08
23 BLA intron excision ratio chr15_47746789_47755535 0.2 0.14 2.3e-03 0.05 0.04 0.05 0.06 8.0e-04 2.7e-03 9.6e-04 3.3e-04
24 NAcc mRNA stability Fndc3a 0.03 0.02 5.9e-03 0.02 0.02 0.02 0.02 3.9e-03 3.9e-03 5.4e-03 5.6e-03
25 Liver gene expression Fndc3a 0.38 0.16 0.0e+00 0.17 0.27 0.26 0.27 3.7e-18 1.9e-29 1.1e-28 1.1e-29

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.30.52.2-0.91.21.5-0.50.50.50.5-0.50.5-0.2-0.2-0.60.70.9-0.30.91.00.70.70.20.60.0-0.9-0.3-0.0
Area under the delay curve0.30.41.1-1.01.00.6-0.80.80.80.8-0.51.1-0.1-0.1-0.10.3-0.9-0.4-0.9-0.80.20.20.10.10.30.2-0.1-0.6
BMI with tail0.20.53.11.2-1.6-1.80.3-0.3-0.3-0.30.3-1.00.60.60.1-0.5-0.60.0-0.7-0.8-0.5-0.4-0.8-0.20.40.6-0.10.8
BMI without tail0.51.03.00.4-0.10.0-0.50.50.50.5-0.8-1.4-0.3-0.3-1.21.11.3-1.01.31.31.11.1-0.61.31.1-1.4-1.41.7
Body weight0.31.35.2-0.80.5-0.2-0.90.90.90.9-1.10.8-1.3-1.3-0.70.5-2.2-1.2-2.2-2.30.50.51.00.41.50.6-0.7-0.1
Weight adjusted by age0.60.72.2-0.1-0.2-0.50.3-0.3-0.3-0.30.50.90.30.30.9-0.9-1.50.6-1.5-1.5-0.9-0.90.3-1.0-0.51.30.9-1.1
Bone surface0.20.41.8-1.11.21.4-0.80.80.80.8-0.60.9-0.2-0.2-0.50.60.1-0.30.10.20.60.60.40.30.1-0.5-0.1-0.4
Bone volume0.20.31.8-1.01.21.4-0.30.30.30.3-0.20.90.10.1-0.20.30.40.00.40.50.30.30.20.1-0.3-0.40.2-0.6
Breakpoint value in progressive ratio session1.21.32.70.8-0.6-0.51.2-1.2-1.2-1.21.5-0.11.31.31.4-1.30.51.40.50.5-1.3-1.3-1.5-1.3-1.70.71.4-0.6
Number of licking bursts0.20.31.00.4-0.5-0.5-0.30.30.30.3-0.5-0.8-0.1-0.1-0.70.50.2-0.70.20.20.50.6-0.10.70.9-0.4-1.00.9
Context. condit. distance diff. score1.92.29.12.3-1.9-1.70.7-0.7-0.7-0.70.0-3.00.90.9-0.80.52.1-0.52.12.00.60.6-1.71.20.9-1.3-1.52.8
Locomotion velocity, session 10.60.62.1-0.1-0.00.10.6-0.6-0.6-0.61.00.60.60.61.0-1.0-0.41.1-0.4-0.4-1.0-1.0-0.4-1.2-1.30.81.4-1.0
Locomotion distance, session 10.40.52.0-1.31.31.4-0.50.50.50.5-0.11.4-0.6-0.60.10.1-0.50.1-0.4-0.40.00.00.8-0.2-0.40.10.5-1.2
Locomotion velocity, session 20.30.41.4-1.11.21.2-0.60.60.60.6-0.21.0-0.5-0.5-0.20.2-0.4-0.1-0.4-0.30.10.10.6-0.1-0.2-0.10.4-0.8
Locomotion distance, session 21.01.45.9-2.12.22.2-0.70.70.70.7-0.22.4-0.9-0.90.3-0.0-0.90.2-0.8-0.8-0.1-0.11.2-0.6-0.80.31.1-2.1
Locomotion velocity, session 30.30.42.31.2-1.4-1.50.4-0.4-0.4-0.40.3-1.10.50.50.1-0.3-0.10.0-0.2-0.2-0.3-0.3-0.6-0.00.40.3-0.30.9
Locomotion distance, session 30.30.31.40.8-0.7-0.70.1-0.1-0.1-0.1-0.1-1.10.30.3-0.50.30.7-0.40.70.70.40.4-0.50.60.6-0.5-0.81.2
Stereotopy head waving bouts, day 30.60.71.30.3-0.5-0.50.9-0.9-0.9-0.91.00.40.80.81.1-1.0-0.51.0-0.5-0.5-1.0-1.0-0.1-1.1-1.01.11.0-1.0
Stereotopy head waving duration, day 31.21.43.50.0-0.5-0.80.8-0.8-0.8-0.81.01.00.50.51.4-1.4-1.81.1-1.8-1.8-1.4-1.40.2-1.5-1.01.91.4-1.5
Locomotion velocity, session 73.94.215.52.2-1.5-1.40.2-0.2-0.2-0.2-0.9-3.70.30.3-1.91.63.0-1.52.92.91.71.7-1.92.41.9-2.5-2.73.9
Locomotion distance, session 72.63.410.91.9-1.2-1.00.6-0.6-0.6-0.6-0.5-3.30.60.6-1.41.23.1-0.93.03.01.31.3-2.01.91.2-2.3-2.03.2
Stereotopy head waving bouts, day 70.70.83.9-0.70.1-0.2-0.60.60.60.6-0.21.2-0.5-0.50.2-0.3-2.0-0.1-2.0-2.0-0.4-0.41.0-0.60.21.10.4-0.9
Stereotopy head waving duration, day 70.70.94.3-0.2-0.4-0.7-0.10.10.10.10.31.0-0.0-0.00.7-0.8-2.00.3-2.1-2.1-0.9-0.90.6-1.0-0.21.50.8-1.0
Locomotion velocity, session 80.20.21.20.8-0.8-0.70.2-0.2-0.2-0.20.1-1.10.30.3-0.30.10.5-0.10.40.40.10.1-0.70.30.3-0.3-0.31.0
Locomotion distance, session 80.40.61.1-0.20.50.6-0.60.60.60.6-0.7-0.4-0.5-0.5-1.01.00.8-0.80.80.81.01.00.11.00.8-1.0-0.90.9
Degree of sensitization distance1.71.76.91.1-0.5-0.10.5-0.5-0.5-0.5-0.2-2.10.50.5-0.80.82.6-0.32.62.60.90.9-1.41.20.3-1.7-1.01.9
Degree of sensitization stereotypy0.40.52.5-0.3-0.1-0.4-0.60.60.60.6-0.30.6-0.5-0.5-0.0-0.1-1.5-0.3-1.6-1.6-0.1-0.10.7-0.20.50.70.1-0.2
Conditioned locomotion0.20.20.70.7-0.6-0.40.6-0.6-0.6-0.60.4-0.70.60.60.3-0.20.80.30.80.8-0.1-0.1-0.30.0-0.3-0.1-0.10.2
Cocaine response after cond. corrected2.32.64.81.9-1.7-1.72.2-2.2-2.2-2.21.8-1.32.02.01.5-1.41.01.61.01.0-1.4-1.4-2.0-1.1-1.40.70.90.1
Cocaine response after cond. not corrected0.70.81.51.2-1.1-1.11.2-1.2-1.2-1.20.9-0.91.21.20.8-0.80.60.80.50.5-0.7-0.7-1.1-0.5-0.70.40.40.2
Cocaine response before conditioning3.03.66.8-2.01.71.6-2.62.62.62.6-2.21.3-2.3-2.3-1.91.7-1.3-2.1-1.3-1.31.71.72.41.42.0-0.8-1.40.2
Saline control response0.30.41.0-0.90.91.0-0.90.90.90.9-0.70.5-0.7-0.7-0.70.70.1-0.60.10.10.70.70.50.50.4-0.6-0.4-0.1
Bone: connectivity density1.01.53.0-0.91.31.6-1.21.21.21.2-1.2-0.0-1.0-1.0-1.51.51.3-1.11.31.41.51.50.41.40.9-1.7-1.10.9
Bone: cortical apparent density1.31.74.92.1-2.0-1.81.5-1.5-1.5-1.51.0-2.21.41.40.4-0.61.40.71.41.3-0.5-0.5-1.8-0.1-0.4-0.2-0.01.4
Bone: cortical area0.00.00.2-0.30.30.4-0.20.20.20.20.00.50.30.30.00.0-0.00.10.00.00.00.00.3-0.0-0.10.00.0-0.4
Bone: cortical porosity2.32.56.3-1.91.51.0-1.91.91.91.9-1.42.1-1.9-1.9-0.70.7-2.5-1.2-2.5-2.50.60.62.10.31.20.6-0.4-1.0
Bone: cortical porosity1.82.04.1-1.91.61.3-1.71.71.71.7-1.22.0-1.5-1.5-0.60.7-2.0-1.0-2.0-1.90.60.61.90.30.90.4-0.3-1.1
Bone: cortical thickness0.10.20.4-0.20.30.3-0.50.50.50.5-0.40.00.30.3-0.50.50.2-0.50.20.20.50.50.10.50.5-0.4-0.60.2
Bone: cortical thickness0.40.41.41.0-0.8-0.70.6-0.6-0.6-0.60.3-1.20.70.7-0.10.00.90.10.90.90.00.0-0.90.30.1-0.3-0.40.9
Bone: cortical tissue density1.51.95.32.2-2.1-1.91.6-1.6-1.6-1.61.1-2.31.51.50.5-0.61.50.81.41.4-0.6-0.6-2.0-0.2-0.5-0.10.01.4
Condit. Reinf. active minus inactive responses0.80.92.2-1.10.70.5-1.01.01.01.0-0.91.1-1.2-1.2-0.40.4-1.5-0.7-1.5-1.50.40.41.40.20.80.3-0.3-0.5
Condit. Reinf. active-inactive response ratio0.50.61.50.5-0.9-1.10.7-0.7-0.7-0.70.60.10.40.40.9-0.8-1.10.5-1.1-1.1-0.8-0.80.0-0.8-0.31.20.4-0.5
Condit. Reinf. active responses2.02.44.6-1.81.61.3-1.91.91.91.9-1.81.3-2.1-2.1-1.31.4-1.4-1.6-1.4-1.41.31.31.91.01.6-0.4-1.0-0.0
Condit. Reinf. inactive responses4.14.98.2-2.72.92.8-2.82.82.82.8-2.51.4-2.8-2.8-2.32.3-0.2-2.3-0.2-0.12.32.32.01.91.9-1.9-1.40.3
Incentive salience index mean3.74.47.8-2.31.71.2-2.52.52.52.5-2.41.8-2.8-2.8-1.61.6-2.6-2.2-2.6-2.61.51.52.71.22.4-0.1-1.4-0.2
Condit. Reinf. lever presses6.18.113.7-2.92.51.8-3.63.63.63.6-3.42.0-3.7-3.7-2.72.5-2.7-3.3-2.7-2.72.52.53.22.13.4-0.8-2.20.2
Condit. Reinf. active minus inactive responses0.30.40.7-0.40.80.7-0.30.30.30.3-0.7-0.0-0.6-0.6-0.70.80.5-0.70.50.50.80.80.30.80.6-0.7-0.80.3
Condit. Reinf. active-inactive response ratio0.00.00.10.3-0.1-0.40.3-0.3-0.3-0.3-0.1-0.4-0.0-0.0-0.10.1-0.0-0.2-0.0-0.00.10.1-0.30.20.3-0.0-0.30.2
Condit. Reinf. active responses0.60.81.5-0.61.10.9-0.70.70.70.7-1.1-0.1-0.9-0.9-1.11.20.7-1.10.70.71.21.20.51.21.0-1.1-1.20.6
Condit. Reinf. inactive responses1.21.52.2-1.01.41.5-1.21.21.21.2-1.30.1-1.2-1.2-1.51.50.8-1.30.80.81.51.50.81.41.1-1.5-1.20.7
Condit. Reinf. lever presses2.33.25.1-2.22.21.8-2.22.22.22.2-2.01.6-2.3-2.3-1.71.6-1.4-1.8-1.4-1.41.51.52.01.21.7-0.7-1.0-0.2
Condit. Reinf. lever reinforcers received0.71.01.7-0.81.21.0-0.90.90.90.9-1.30.2-1.1-1.1-1.31.30.3-1.30.30.31.31.30.71.31.2-1.0-1.30.6
Conditioned reinforcement - actives1.61.66.41.4-0.70.00.2-0.2-0.2-0.20.6-2.01.81.8-0.20.12.50.42.52.50.10.1-1.30.4-0.4-1.3-0.31.7
Conditioned reinforcement - inactives1.82.14.2-1.32.01.9-1.31.31.31.3-1.70.1-0.6-0.6-1.91.90.8-1.70.90.91.91.9-0.11.81.4-1.9-1.61.1
Conditioned locomotion0.40.41.2-0.60.91.1-0.70.70.70.7-0.40.10.70.7-0.50.60.8-0.40.80.90.60.6-0.60.50.0-0.9-0.20.3
Patch foraging indifference point 0 sec3.96.310.6-2.93.22.8-2.72.72.72.7-3.11.2-3.0-3.0-2.92.9-0.3-3.0-0.3-0.32.92.92.02.52.6-2.3-2.30.5
Patch foraging indifference point AUC2.02.34.21.7-1.6-1.52.0-2.0-2.0-2.01.7-0.82.02.01.7-1.50.51.70.50.5-1.5-1.5-1.4-1.3-1.41.11.0-0.4
Delay disc. indifference point, 0s delay0.70.82.5-1.61.31.5-1.11.11.11.1-0.61.5-1.0-1.0-0.20.4-0.4-0.3-0.4-0.40.40.41.40.1-0.1-0.20.3-1.0
Delay disc. indifference point, 16s delay0.30.31.1-0.81.11.1-0.70.70.70.7-0.00.90.50.5-0.10.00.00.10.10.10.00.0-0.7-0.2-0.4-0.30.3-0.6
Delay disc. indifference point, 2s delay0.70.82.5-0.50.1-0.20.2-0.2-0.2-0.20.51.30.60.61.1-0.9-1.40.6-1.4-1.4-0.9-0.90.1-1.1-0.81.31.0-1.6
Delay disc. indifference point, 24s delay0.10.10.50.3-0.2-0.50.2-0.2-0.2-0.20.2-0.00.60.60.3-0.4-0.40.2-0.4-0.4-0.4-0.4-0.7-0.3-0.10.50.1-0.0
Delay disc. indifference point, 4s delay0.50.61.90.0-0.3-0.50.7-0.7-0.7-0.70.40.60.50.51.1-0.7-1.10.6-1.1-1.1-0.7-0.7-0.0-0.8-0.41.40.6-1.1
Delay disc. indifference point, 8s delay0.40.50.8-0.80.90.6-0.90.90.90.9-0.90.5-0.5-0.5-0.70.7-0.5-0.8-0.5-0.50.70.7-0.00.60.8-0.3-0.60.0
Indifference point function ln k1.92.66.1-1.71.51.1-1.91.91.91.9-1.90.9-2.5-2.5-1.81.5-1.2-1.8-1.2-1.21.51.51.81.31.9-0.8-1.30.2
Indifference point function log k1.92.66.1-1.71.51.1-1.91.91.91.9-1.90.9-2.5-2.5-1.81.5-1.2-1.8-1.2-1.21.51.51.81.31.9-0.8-1.30.2
Patch foraging total patch changes 0 sec3.65.810.6-2.93.32.8-2.62.62.62.6-2.91.3-2.9-2.9-2.82.8-0.4-2.8-0.4-0.42.72.71.92.42.4-2.1-2.10.3
Patch foraging total patch changes 12 sec0.81.03.2-1.51.81.7-0.90.90.90.9-1.11.0-1.3-1.3-0.91.10.0-0.90.10.11.01.00.90.80.6-0.9-0.6-0.4
Patch foraging total patch changes 18 sec0.50.62.2-0.20.70.8-0.10.10.10.1-0.5-0.4-0.0-0.0-0.80.91.4-0.61.51.50.90.9-0.80.90.3-1.4-0.70.7
Patch foraging total patch changes 24 sec0.81.02.2-1.51.41.1-1.21.21.21.2-1.21.2-0.3-0.3-0.91.0-0.9-1.1-0.9-0.90.90.90.80.71.0-0.3-0.7-0.6
Patch foraging total patch changes 6 sec0.81.23.2-0.20.50.3-0.90.90.90.9-1.3-0.6-0.9-0.9-1.41.40.4-1.50.40.41.41.40.41.51.6-1.2-1.81.1
Patch foraging time to switch 0 sec0.10.20.6-0.40.50.8-0.50.50.50.5-0.20.10.10.1-0.40.30.7-0.10.70.70.30.3-0.20.2-0.1-0.70.10.3
Patch foraging water rate 0 sec0.30.52.2-0.60.60.2-0.50.50.50.5-0.70.5-1.5-1.5-0.40.5-0.9-0.7-0.9-0.90.40.41.00.40.80.0-0.5-0.2
Patch foraging water rate 12 sec0.10.10.6-0.0-0.2-0.2-0.30.30.30.3-0.00.1-0.8-0.8-0.0-0.1-0.6-0.0-0.6-0.6-0.1-0.10.6-0.10.20.4-0.1-0.4
Patch foraging water rate 18 sec0.40.52.60.8-1.2-1.60.5-0.5-0.5-0.50.2-0.4-0.4-0.40.5-0.5-1.10.0-1.2-1.2-0.5-0.50.3-0.30.41.2-0.2-0.1
Patch foraging water rate 24 sec0.30.52.21.3-1.1-1.30.6-0.6-0.6-0.60.2-1.5-0.5-0.5-0.1-0.00.6-0.20.50.50.00.0-0.60.30.4-0.3-0.61.1
Patch foraging water rate 6 sec0.40.71.70.1-0.4-0.60.5-0.5-0.5-0.50.60.6-0.1-0.10.9-1.0-1.30.6-1.3-1.3-1.0-1.0-0.1-1.0-0.61.21.0-1.1
Seeking ratio, delayed vs. immediate footshock0.60.71.2-0.91.01.1-1.01.01.01.0-0.90.5-0.9-0.9-0.90.90.3-0.80.30.30.90.90.70.80.6-0.9-0.60.2
Distance traveled before self-admin1.21.33.6-0.4-0.3-0.20.4-0.4-0.4-0.41.11.40.60.61.3-1.3-1.11.5-1.0-1.0-1.4-1.40.0-1.6-1.61.41.8-1.9
Distance traveled after self-admin2.83.14.61.8-2.0-2.22.1-2.1-2.1-2.12.0-0.72.12.11.9-2.1-0.32.0-0.3-0.3-2.0-2.0-2.0-1.9-1.71.61.7-0.5
Extensor digitorum longus weight6.023.646.92.4-3.8-4.64.5-4.5-4.5-4.55.11.84.14.16.0-6.1-4.85.1-4.8-4.9-6.1-6.1-1.9-6.1-4.56.95.4-4.6
Bone: elastic displacement0.30.42.5-1.11.31.6-0.40.40.40.4-0.11.1-0.4-0.4-0.10.20.30.20.30.40.20.20.4-0.1-0.6-0.40.5-0.8
Bone: elastic work1.01.25.4-2.12.12.3-1.21.21.21.2-0.52.2-0.4-0.4-0.30.4-0.6-0.1-0.5-0.50.30.31.0-0.1-0.4-0.20.7-1.5
Bone: endosteal estimation0.10.31.0-0.40.3-0.00.4-0.4-0.4-0.40.10.8-0.3-0.30.5-0.4-1.00.2-1.0-1.0-0.4-0.40.3-0.5-0.20.80.5-0.8
Bone: endosteal perimeter0.10.31.0-0.60.40.2-0.00.00.00.00.11.0-0.4-0.40.4-0.3-0.90.3-0.8-0.8-0.4-0.40.7-0.5-0.30.60.6-1.0
Epididymis fat weight1.84.26.8-1.21.81.6-2.02.02.02.0-2.4-0.5-2.1-2.1-2.62.61.2-2.51.21.22.62.61.02.62.3-2.6-2.61.9
Delta time in closed arm before/after self-admin0.60.61.2-0.70.91.0-0.90.90.90.9-0.70.2-0.6-0.6-0.90.90.8-0.60.80.80.90.80.20.80.3-1.1-0.50.3
Delta time in open arm before/after self-admin0.10.10.30.2-0.2-0.3-0.20.20.20.2-0.2-0.3-0.2-0.2-0.30.20.0-0.20.00.00.20.20.10.30.4-0.3-0.30.6
Diff in mean of infusions in LGA sessions2.62.94.41.6-1.8-2.02.1-2.1-2.1-2.11.9-0.51.81.82.0-2.0-0.51.9-0.5-0.5-2.0-2.0-1.6-1.8-1.61.81.7-0.8
Delay discount exponential model param0.30.41.20.8-0.8-0.40.7-0.7-0.7-0.70.5-1.00.00.00.0-0.21.10.41.11.1-0.2-0.20.1-0.0-0.4-0.40.10.5
Extinction: sum of active levers before priming0.60.62.0-0.20.70.8-0.40.40.40.4-0.5-0.5-0.2-0.2-0.90.81.4-0.41.41.40.90.9-0.30.90.3-1.3-0.60.7
Active lever presses in extinction session 60.30.30.90.5-0.3-0.40.2-0.2-0.2-0.2-0.2-0.9-0.0-0.0-0.30.40.7-0.50.70.60.40.4-0.60.60.5-0.6-0.80.9
Bone: final force0.50.72.0-0.60.40.0-0.90.90.90.9-1.10.4-0.8-0.8-0.90.8-1.1-1.1-1.1-1.10.80.80.90.81.4-0.0-1.00.2
Bone: final moment0.50.81.5-0.90.80.4-0.90.90.90.9-1.10.8-0.7-0.7-0.90.8-1.1-1.1-1.1-1.10.80.80.90.71.20.0-0.8-0.1
Food consumed during 24 hour testing period0.40.51.3-1.11.10.9-0.80.80.80.8-0.80.9-1.0-1.0-0.60.6-0.5-0.7-0.5-0.50.60.60.90.40.6-0.2-0.3-0.2
Glucose1.01.52.71.6-1.4-1.11.5-1.5-1.5-1.51.4-1.21.61.61.0-0.91.31.21.41.4-0.8-0.8-1.3-0.6-1.10.20.40.2
Heart weight0.10.10.4-0.50.60.4-0.30.30.30.3-0.50.2-0.5-0.5-0.30.4-0.2-0.5-0.2-0.20.40.40.30.40.5-0.3-0.40.0
Delay discount hyperbolic model param0.40.41.70.8-0.7-0.20.4-0.4-0.4-0.40.2-1.2-0.1-0.1-0.40.11.30.11.31.30.20.2-0.00.3-0.1-0.7-0.20.9
Intermittent access intake day 1-15 change1.71.73.2-0.71.21.2-0.90.90.90.9-1.4-0.3-1.1-1.1-1.71.71.0-1.51.01.11.71.71.01.71.4-1.8-1.61.2
Intermittent access intake escalation1.01.02.1-0.30.90.8-0.50.50.50.5-1.0-0.5-0.8-0.8-1.21.31.0-1.11.11.11.31.30.61.31.0-1.4-1.31.1
Intermittent access intake escalation 20.40.40.8-0.10.50.3-0.10.10.10.1-0.6-0.4-0.8-0.8-0.70.80.8-0.70.80.80.80.80.70.90.6-0.9-0.90.8
Intermitt. access day 1 inactive lever presses0.30.30.8-0.30.50.20.1-0.1-0.1-0.1-0.8-0.2-0.5-0.5-0.60.7-0.1-0.9-0.1-0.10.70.7-0.50.80.9-0.3-0.90.6
Intermitt. access day 15 inactive lever presses0.70.82.0-1.00.70.5-0.90.90.90.9-1.10.5-1.3-1.3-0.81.0-0.5-1.2-0.5-0.51.01.01.40.91.0-0.4-0.90.0
Intermitt. access escalation Index0.70.61.20.5-0.9-0.80.7-0.7-0.7-0.71.00.20.80.81.0-1.1-0.21.1-0.2-0.2-1.1-1.1-0.2-1.1-1.00.91.1-0.7
Intermittent access day 1 total infusions0.30.30.7-0.20.40.2-0.70.70.70.7-0.7-0.30.10.1-0.80.70.2-0.80.20.10.70.7-0.40.70.8-0.6-0.80.8
Intermittent access day 15 total infusions1.01.12.2-0.30.80.7-0.80.80.80.8-1.2-0.6-0.5-0.5-1.41.41.0-1.31.01.01.41.40.11.51.2-1.5-1.51.4
Intermittent access terminal intake (last 3 days)0.40.51.30.10.20.0-0.30.30.30.3-0.7-0.80.00.0-0.80.90.8-0.90.80.80.90.9-0.01.00.8-0.9-1.01.1
Intermittent access total infusions0.80.92.0-0.10.50.3-0.70.70.70.7-1.0-0.8-0.2-0.2-1.21.20.8-1.30.80.71.21.20.11.31.2-1.1-1.41.4
Intermittent access day 1 locomotion1.41.43.1-1.01.20.9-1.41.41.41.4-1.60.1-0.7-0.7-1.61.5-0.1-1.8-0.1-0.21.51.50.01.51.7-1.1-1.51.0
Intermittent access day 15 total locomotion0.90.92.30.10.50.6-0.40.40.40.4-0.8-1.00.30.3-1.11.11.3-0.91.31.31.11.1-1.01.20.9-1.5-1.21.5
Intermittent access total locomotion0.91.02.2-0.81.00.7-1.01.01.01.0-1.3-0.1-0.5-0.5-1.31.40.3-1.50.30.31.41.40.11.31.3-1.1-1.40.9
Intermittent access standard deviation0.30.31.3-0.30.20.6-0.30.30.30.3-0.2-0.1-0.3-0.3-0.30.51.1-0.11.11.10.50.50.90.4-0.1-0.8-0.20.2
Left kidney weight1.85.29.8-2.21.70.9-2.32.32.32.3-2.91.4-3.1-3.1-2.12.1-2.6-2.8-2.6-2.72.02.02.61.83.1-0.2-2.00.2
Right kidney weight3.910.820.2-3.83.62.7-3.53.53.53.5-4.22.3-4.5-4.5-3.23.4-2.4-4.0-2.4-2.43.33.34.02.83.9-1.3-2.80.1
Cocaine induced anxiety1.51.76.2-1.91.11.2-1.51.51.51.5-0.22.5-0.4-0.40.3-0.3-1.70.2-1.7-1.6-0.4-0.41.8-0.8-0.60.91.2-2.1
Post-drug Anxiety1.11.25.0-1.10.60.7-1.61.61.61.6-1.10.6-1.3-1.3-1.11.0-0.3-1.1-0.3-0.31.01.02.20.90.9-0.6-0.80.2
Baseline Anxiety1.21.23.00.40.1-0.0-0.20.20.20.2-1.0-1.3-1.4-1.4-1.31.31.0-1.21.01.01.31.30.51.51.5-1.4-1.71.7
Tail length1.13.56.7-2.12.62.4-2.12.12.12.1-2.21.0-2.3-2.3-2.02.10.1-2.00.20.22.12.11.71.91.7-1.8-1.70.4
Length with tail0.41.53.3-1.81.71.1-0.90.90.90.9-1.31.7-1.7-1.7-0.60.7-1.8-1.1-1.8-1.80.70.71.60.41.00.2-0.5-0.9
Length without tail1.12.410.6-0.3-0.5-1.20.7-0.7-0.7-0.70.61.50.00.01.4-1.4-3.20.7-3.2-3.3-1.5-1.50.6-1.6-0.42.51.2-1.8
Times rat made contact with spout1.31.53.5-0.00.00.1-1.11.11.11.1-1.4-1.0-0.9-0.9-1.71.50.6-1.60.60.61.51.50.31.71.8-1.4-1.91.6
Lifetime Intake0.60.71.6-0.10.50.5-0.80.80.80.8-0.9-0.60.00.0-1.11.10.7-1.10.70.71.11.1-0.01.11.0-1.0-1.21.3
Liver weight, left0.50.83.00.2-0.7-1.00.3-0.3-0.3-0.30.50.70.30.30.9-0.9-1.70.4-1.7-1.7-0.9-0.90.5-0.9-0.31.60.6-0.9
Liver weight, right0.50.81.40.7-0.9-1.01.0-1.0-1.0-1.00.90.10.90.91.2-1.1-0.70.9-0.7-0.7-1.1-1.1-0.4-1.0-0.71.20.7-0.6
Locomotor activity2.64.118.1-3.02.52.2-0.90.90.90.90.04.3-0.0-0.01.2-0.9-3.00.8-2.9-2.8-1.0-1.01.6-1.7-1.32.02.2-3.9
Locomotor testing distance1.83.113.7-3.33.13.0-1.61.61.61.6-0.83.7-0.5-0.50.10.3-1.8-0.1-1.7-1.60.20.21.7-0.5-0.60.51.1-2.8
Locomotor testing rearing2.43.815.0-3.73.53.4-2.02.02.02.0-1.33.9-1.1-1.1-0.30.7-1.8-0.6-1.7-1.60.60.62.0-0.2-0.20.10.8-2.7
Locomotion in novel chamber0.40.52.7-1.21.51.6-0.90.90.90.9-0.41.2-0.4-0.4-0.10.3-0.2-0.1-0.2-0.20.30.30.8-0.0-0.2-0.20.3-0.8
Locomotion in novel chamber post-restriction0.40.51.60.7-0.5-0.70.7-0.7-0.7-0.70.7-0.21.31.30.7-0.7-0.10.6-0.1-0.1-0.7-0.7-1.1-0.6-0.60.70.4-0.4
Fecal boli incidents, locomotor time 10.50.62.1-0.70.40.1-0.20.20.20.20.21.30.10.10.6-0.6-1.40.3-1.4-1.4-0.6-0.60.1-0.8-0.41.10.9-1.1
Change in fecal boli incidents, locomotor task0.10.10.30.5-0.6-0.40.5-0.5-0.5-0.50.4-0.4-0.2-0.20.2-0.30.30.40.30.3-0.3-0.30.2-0.2-0.30.20.2-0.1
Time >=10cm from walls, locomotor time 11.11.11.8-1.21.31.3-1.31.31.31.3-1.20.6-1.3-1.3-1.21.20.1-1.10.10.11.21.20.71.00.9-1.0-0.60.5
Bouts of movement, locomotor time 11.71.94.81.4-1.7-2.21.7-1.7-1.7-1.71.1-0.71.11.11.4-1.5-1.21.0-1.2-1.3-1.5-1.4-1.4-1.2-0.61.80.8-0.5
Total resting periods, locomotor time 12.12.35.71.7-2.0-2.41.9-1.9-1.9-1.91.3-0.81.31.31.5-1.6-1.01.3-1.1-1.1-1.6-1.6-1.5-1.4-0.71.91.0-0.4
Rest time, locomotor task time 11.92.13.90.9-1.3-1.41.4-1.4-1.4-1.41.60.31.21.21.7-1.9-1.11.7-1.1-1.2-1.9-1.9-0.8-1.9-1.52.01.8-1.3
Distance moved, locomotor task time 11.61.74.5-0.51.01.1-1.11.11.11.1-1.3-0.6-0.9-0.9-1.61.61.4-1.51.41.41.61.60.01.71.2-2.1-1.71.4
Vertical activity count, locomotor time 10.30.41.7-0.70.91.3-0.50.50.50.50.30.80.40.40.1-0.00.70.30.80.8-0.0-0.0-0.0-0.2-0.9-0.60.4-0.8
Time >=10cm from walls, locomotor time 20.70.72.00.1-0.2-0.10.5-0.5-0.5-0.51.00.71.01.01.1-1.1-0.51.1-0.5-0.5-1.1-1.1-0.6-1.3-1.21.01.4-0.8
Bouts of movement, locomotor time 22.62.85.41.8-2.1-2.31.9-1.9-1.9-1.91.7-0.61.81.81.8-1.9-0.91.7-1.0-1.0-1.9-1.9-1.5-1.7-1.22.11.4-0.6
Total resting periods, locomotor time 22.62.85.71.7-2.1-2.41.9-1.9-1.9-1.91.7-0.61.71.71.8-1.9-1.11.6-1.1-1.1-1.9-1.9-1.3-1.7-1.12.11.3-0.6
Rest time, locomotor task time 21.01.22.11.2-1.4-1.41.3-1.3-1.3-1.31.2-0.51.01.01.2-1.3-0.11.1-0.2-0.2-1.3-1.3-0.9-1.1-1.01.20.9-0.3
Distance moved, locomotor task time 21.71.94.3-1.41.82.1-1.71.71.71.7-1.40.6-1.2-1.2-1.51.50.8-1.40.80.81.51.50.71.30.9-1.8-1.20.5
Vertical activity count, locomotor time 20.60.62.4-0.81.01.4-0.30.30.30.30.71.30.70.70.7-0.60.40.80.40.5-0.6-0.6-0.2-0.9-1.5-0.21.1-1.4
Light reinforcement 11.73.27.7-0.00.71.0-1.01.01.01.0-1.6-1.7-0.3-0.3-2.22.22.4-1.82.42.42.22.2-0.72.41.7-2.8-2.32.4
Light reinforcement 21.82.48.41.9-1.5-1.00.4-0.4-0.4-0.4-0.2-2.91.01.0-1.00.82.6-0.52.62.60.90.9-1.71.30.8-1.7-1.52.6
Bone: marrow area0.10.20.9-0.50.50.10.3-0.3-0.3-0.30.00.8-0.4-0.40.3-0.3-0.90.1-0.9-0.9-0.3-0.30.4-0.4-0.10.70.4-0.8
Bone: maximum diameter0.20.50.90.8-0.9-1.00.8-0.8-0.8-0.80.9-0.20.40.40.8-0.8-0.20.8-0.2-0.2-0.8-0.8-0.0-0.7-0.60.80.5-0.3
Bone: maximum force0.30.51.6-0.90.80.3-0.50.50.50.5-0.61.0-0.7-0.7-0.30.3-1.3-0.5-1.3-1.30.20.21.00.10.60.5-0.2-0.6
Bone: maximum moment0.40.72.1-1.31.30.8-0.60.60.60.6-0.71.4-0.8-0.8-0.30.4-1.3-0.5-1.3-1.20.30.31.10.10.50.4-0.1-1.0
Mean time between licks in bursts0.60.93.5-0.61.21.5-0.20.20.20.2-0.5-0.1-0.4-0.4-0.71.01.8-0.41.81.91.01.00.10.90.1-1.4-0.60.4
Mean num. licks in bursts0.10.10.2-0.20.30.4-0.20.20.20.2-0.1-0.0-0.2-0.2-0.20.30.4-0.20.40.40.30.3-0.00.30.0-0.5-0.10.2
Cd content in liver0.10.10.50.20.20.30.1-0.1-0.1-0.1-0.1-0.3-0.3-0.3-0.20.30.7-0.20.70.70.30.30.10.40.1-0.5-0.40.4
Co content in liver5.05.810.02.5-2.6-2.62.8-2.8-2.8-2.82.9-0.83.23.22.8-2.8-0.22.6-0.2-0.2-2.8-2.7-2.4-2.4-2.42.32.0-0.9
Cu content in liver1.01.22.20.7-0.8-0.71.3-1.3-1.3-1.31.50.10.80.81.5-1.4-0.11.4-0.1-0.1-1.4-1.4-0.5-1.4-1.51.11.3-0.9
Fe content in liver0.70.81.7-0.51.01.2-0.50.50.50.5-0.7-0.2-0.8-0.8-0.91.11.2-0.71.31.31.11.10.41.10.5-1.3-0.80.6
K content in liver0.70.61.60.10.10.0-0.40.40.40.4-0.9-0.9-0.7-0.7-1.01.00.7-1.00.60.61.01.00.11.11.1-1.0-1.31.3
Mg content in liver0.40.42.20.5-0.20.10.4-0.4-0.4-0.40.1-0.90.10.1-0.20.31.50.01.51.50.30.3-0.40.4-0.1-0.8-0.40.8
Mn content in liver0.50.53.30.20.30.60.3-0.3-0.3-0.30.1-0.6-0.5-0.5-0.20.31.80.11.81.80.40.3-0.00.4-0.4-1.0-0.20.4
Na content in liver2.83.010.0-2.72.42.0-1.61.61.61.6-1.03.2-1.7-1.7-0.10.3-2.5-0.5-2.5-2.40.20.22.3-0.40.10.90.7-2.2
Rb content in liver0.30.41.20.5-0.3-0.30.4-0.4-0.4-0.4-0.2-0.9-1.1-1.1-0.30.40.8-0.30.80.70.40.40.40.60.5-0.6-0.71.0
Se content in liver1.21.57.4-2.12.52.7-0.70.70.70.70.12.5-0.8-0.80.4-0.0-0.00.50.10.2-0.1-0.11.2-0.6-1.3-0.01.2-2.2
Sr content in liver0.30.31.4-0.20.40.50.1-0.1-0.1-0.10.30.11.21.20.1-0.10.60.40.60.6-0.1-0.1-1.0-0.2-0.6-0.30.5-0.2
Zn content in liver1.31.46.0-1.71.41.1-0.80.80.80.8-0.22.40.60.60.5-0.4-2.00.1-2.0-1.9-0.4-0.40.6-0.8-0.41.10.9-2.0
Bone: minimum diameter0.40.72.7-1.11.00.8-0.70.70.70.7-0.21.6-0.5-0.50.1-0.0-1.2-0.1-1.1-1.1-0.0-0.01.5-0.2-0.00.60.3-1.2
Time in familiar zone, hab. session 10.50.51.60.2-0.3-0.6-0.60.60.60.6-0.8-0.7-0.6-0.6-0.90.7-0.3-1.0-0.4-0.40.70.7-0.00.81.3-0.4-1.01.1
Time in novel zone, hab. session 14.03.96.21.7-1.9-1.62.3-2.3-2.3-2.32.5-0.52.42.42.4-2.30.42.50.40.4-2.3-2.3-1.5-2.1-2.41.62.0-1.1
Total zone transitions, hab. session 10.20.31.2-0.50.30.4-0.00.00.00.00.40.9-0.0-0.00.6-0.5-0.70.5-0.7-0.7-0.5-0.50.5-0.7-0.70.60.8-1.1
Total locomotion distance, hab. session 10.50.72.1-1.51.31.3-1.01.01.01.0-0.51.4-0.9-0.9-0.20.3-0.7-0.2-0.7-0.70.20.21.2-0.1-0.10.00.3-1.0
Locomotion velocity, hab. session 11.42.05.7-2.42.22.2-1.71.71.71.7-1.02.2-1.7-1.7-0.70.8-1.0-0.7-1.0-0.90.70.72.00.20.2-0.30.2-1.3
Time in familiar zone, hab. session 21.92.04.61.8-2.0-2.11.7-1.7-1.7-1.71.4-1.21.61.61.3-1.5-0.21.2-0.3-0.4-1.5-1.5-1.9-1.2-0.91.21.00.3
Time in novel zone, hab. session 20.30.31.4-0.91.01.2-0.50.50.50.5-0.30.8-0.4-0.4-0.20.40.3-0.10.40.40.40.40.90.2-0.2-0.4-0.0-0.6
Total zone transitions, hab. session 21.21.54.9-1.20.90.7-0.20.20.20.20.52.2-0.2-0.21.0-0.9-2.00.8-2.0-2.0-1.0-1.01.0-1.4-0.91.51.5-2.2
Total locomotion distance, hab. session 20.50.72.7-1.10.90.9-0.30.30.30.30.21.6-0.4-0.40.6-0.5-1.10.5-1.1-1.1-0.5-0.50.9-0.8-0.70.81.0-1.5
Locomotion velocity, hab. session 20.81.14.0-1.31.00.9-0.30.30.30.30.32.0-0.4-0.40.7-0.6-1.50.6-1.5-1.5-0.7-0.71.0-1.0-0.81.11.3-2.0
Novel to familiar place preference ratio0.90.92.1-1.11.31.4-1.11.11.11.1-1.00.5-1.0-1.0-1.21.10.5-0.90.50.51.11.10.91.00.7-1.0-0.70.2
Novelty place preference1.01.01.8-1.11.21.3-1.21.21.21.2-1.10.5-1.1-1.1-1.21.10.3-1.00.30.41.11.11.01.00.8-1.0-0.70.2
Time in novel zone, NPP test0.50.61.1-0.91.11.0-0.90.90.90.9-0.80.5-0.8-0.8-0.90.90.2-0.80.20.20.80.80.70.70.6-0.7-0.50.1
Total zone transitions, NPP test0.50.63.0-1.51.71.7-0.60.60.60.6-0.51.5-0.8-0.8-0.10.4-0.4-0.2-0.3-0.30.30.31.00.0-0.1-0.10.2-1.1
Total locomotion distance, NPP test1.31.87.7-2.12.52.8-1.31.31.31.3-1.11.4-1.4-1.4-1.01.30.7-0.80.80.81.31.31.40.90.2-1.3-0.5-0.6
Locomotion velocity, NPP test1.52.17.6-2.12.62.8-1.51.51.51.5-1.31.3-1.6-1.6-1.21.50.6-1.10.70.81.51.51.51.10.5-1.4-0.7-0.5
Intraocular pressure0.30.51.0-0.20.30.6-0.60.60.60.6-0.6-0.4-0.2-0.2-0.90.81.0-0.51.01.00.90.90.10.90.5-0.9-0.70.6
Delta distance traveled before/after self-admin2.93.17.62.8-2.3-2.72.4-2.4-2.4-2.41.6-2.12.02.01.3-1.60.11.20.0-0.0-1.5-1.5-2.6-1.0-0.61.20.51.0
Delta ambulatory time before/after self-admin1.81.95.42.1-2.0-2.31.9-1.9-1.9-1.91.2-1.61.51.51.1-1.3-0.30.9-0.3-0.4-1.2-1.2-1.7-0.9-0.41.10.40.6
Parametrial fat weight1.12.17.70.50.40.8-0.20.20.20.2-0.7-1.7-0.1-0.1-1.31.42.7-0.92.82.81.41.4-0.91.60.7-2.3-1.62.0
Pavlov. Cond. lever latency2.73.46.41.5-1.2-0.92.5-2.5-2.5-2.52.3-0.52.22.22.1-1.81.12.31.21.2-1.8-1.8-1.6-1.7-2.41.01.8-0.9
Pavlov. Cond. magazine entry latency0.70.91.9-0.40.30.2-1.31.31.31.3-1.2-0.2-1.0-1.0-1.21.1-0.2-1.3-0.2-0.21.11.10.51.11.4-0.8-1.20.9
Pavlov. Cond. change in total contacts1.41.43.1-1.10.60.3-1.71.71.71.7-1.30.9-1.4-1.4-0.90.7-1.7-1.3-1.7-1.80.70.71.30.51.30.1-0.8-0.1
Pavlov. Cond. index score2.22.85.4-1.30.90.7-2.32.32.32.3-2.10.5-2.0-2.0-1.81.6-1.3-2.1-1.3-1.31.61.61.51.52.2-0.8-1.70.8
Pavlov. Cond. latency score2.93.76.9-1.41.10.8-2.62.62.62.6-2.40.5-2.3-2.3-2.21.9-1.2-2.4-1.3-1.31.91.91.71.82.6-1.0-1.91.0
Pavlov. Cond. lever contacts2.93.46.5-1.61.31.1-2.52.52.52.5-2.20.7-2.2-2.2-2.01.8-1.1-2.2-1.1-1.21.81.81.71.62.3-1.0-1.70.7
Pavlov. Cond. magazine entry number0.20.30.80.20.10.20.8-0.8-0.8-0.80.6-0.20.50.50.4-0.30.90.60.90.9-0.3-0.3-0.5-0.3-0.8-0.20.5-0.2
Pavlov. Cond. intertrial magazine entries1.51.83.4-1.61.51.2-1.71.71.71.7-1.51.1-1.8-1.8-1.11.1-1.1-1.4-1.1-1.01.11.11.80.91.3-0.4-0.8-0.1
Pavlov. Cond. lever-magazine prob. diff.1.92.44.7-1.20.80.5-2.22.22.22.2-1.80.6-1.8-1.8-1.61.4-1.4-1.9-1.4-1.41.31.31.41.22.0-0.6-1.40.6
Pavlov. Cond. response bias0.80.92.0-0.70.40.2-1.41.41.41.4-1.20.4-1.1-1.1-1.00.8-0.9-1.2-0.9-0.90.80.80.90.81.3-0.3-1.00.4
Pavlov. Cond. lever latency1.31.73.61.8-1.4-1.11.6-1.6-1.6-1.61.2-1.81.61.60.8-0.61.91.01.91.9-0.6-0.6-1.6-0.2-0.9-0.20.20.9
Pavlov. Cond. magazine entry latency1.21.43.2-1.81.61.4-1.51.51.51.5-1.21.5-1.6-1.6-0.90.9-1.1-1.0-1.1-1.10.80.81.50.50.8-0.3-0.3-0.5
Pavlov. Cond. change in total contacts0.91.24.0-1.00.60.3-0.20.20.20.20.31.8-0.2-0.20.8-0.8-2.00.6-2.0-2.0-0.9-0.91.0-1.2-0.71.51.2-1.8
Pavlov. Cond. index score1.41.84.6-1.91.51.1-1.51.51.51.5-0.92.1-1.5-1.5-0.40.3-2.1-0.6-2.1-2.10.20.21.8-0.20.50.60.3-1.3
Pavlov. Cond. latency score1.72.14.8-2.11.71.4-1.71.71.71.7-1.12.2-1.7-1.7-0.60.5-2.1-0.8-2.1-2.10.40.41.90.00.60.40.2-1.3
Pavlov. Cond. lever contacts1.72.45.5-2.31.91.5-1.81.81.81.8-1.22.4-1.7-1.7-0.60.6-2.2-0.9-2.2-2.10.50.51.90.00.60.40.2-1.3
Pavlov. Cond. magazine entry number1.01.32.21.5-1.3-1.01.4-1.4-1.4-1.41.2-1.11.51.51.0-0.91.01.11.11.0-0.9-0.9-1.4-0.6-1.00.30.50.2
Pavlov. Cond. intertrial magazine entries2.93.88.0-0.61.21.7-1.61.61.61.6-1.9-1.0-1.3-1.3-2.32.42.3-2.02.32.42.52.50.62.61.8-2.8-2.51.9
Pavlov. Cond. lever-magazine prob. diff.1.21.64.3-1.71.31.0-1.31.31.31.3-0.82.0-1.3-1.3-0.30.2-2.1-0.6-2.1-2.10.20.21.7-0.20.40.70.3-1.2
Pavlov. Cond. response bias1.72.35.9-2.31.81.5-1.71.71.71.7-1.02.4-1.6-1.6-0.50.4-2.2-0.7-2.2-2.20.30.31.9-0.10.50.50.4-1.5
Time in closed arm before self-admin0.20.21.10.4-0.3-0.60.3-0.3-0.3-0.30.0-0.1-0.1-0.10.2-0.2-1.0-0.1-1.0-1.0-0.2-0.20.1-0.20.50.8-0.10.2
Time in closed arm after self-admin0.10.10.50.0-0.3-0.20.1-0.1-0.1-0.10.10.20.10.10.2-0.3-0.60.1-0.6-0.6-0.3-0.30.3-0.3-0.00.70.2-0.3
Time in open arm before self-admin0.70.82.00.6-0.8-0.80.9-0.9-0.9-0.91.1-0.21.11.10.9-1.00.11.10.10.1-1.0-1.0-1.4-1.0-1.20.61.1-0.7
Time in open arm after self-admin0.10.10.70.3-0.5-0.50.1-0.1-0.1-0.10.3-0.30.30.30.0-0.20.20.20.20.2-0.2-0.2-0.9-0.2-0.2-0.30.20.3
Bone: periosteal estimation0.10.10.5-0.30.30.10.2-0.2-0.2-0.20.20.70.00.00.3-0.2-0.60.2-0.5-0.5-0.3-0.30.4-0.3-0.20.50.3-0.7
Bone: periosteal perimeter0.00.10.2-0.10.10.10.1-0.1-0.1-0.10.20.4-0.1-0.10.3-0.2-0.20.2-0.1-0.1-0.2-0.20.5-0.2-0.30.30.2-0.5
Bone: post-yield work0.30.41.30.7-0.4-0.60.4-0.4-0.4-0.4-0.2-1.2-0.1-0.1-0.50.50.8-0.50.70.70.50.5-0.50.70.6-0.6-0.91.0
Progressive ratio test 1 active lever presses0.50.52.61.2-0.7-0.90.8-0.8-0.8-0.80.3-1.31.11.1-0.0-0.20.40.00.40.3-0.1-0.1-1.60.10.2-0.0-0.31.1
Progressive ratio test 1 breakpoint0.70.72.91.4-0.8-1.00.9-0.9-0.9-0.90.3-1.51.11.1-0.1-0.10.7-0.00.60.6-0.1-0.1-1.70.20.2-0.2-0.41.3
Progressive ratio test 1 inactive lever presses1.41.63.50.20.50.5-0.70.70.70.7-1.1-1.4-0.6-0.6-1.61.51.4-1.51.41.41.51.5-0.41.71.4-1.8-1.81.9
Progressive ratio test 2 active lever presses1.11.25.11.6-1.0-1.10.7-0.7-0.7-0.7-0.1-2.30.90.9-0.50.41.4-0.51.41.30.50.5-1.20.90.8-0.9-1.22.1
Progressive ratio test 2 breakpoint0.80.93.91.1-0.6-0.70.2-0.2-0.2-0.2-0.5-1.90.50.5-0.80.81.1-0.91.11.10.80.8-0.71.11.1-1.0-1.42.0
Progressive ratio test 2 inactive lever presses0.70.81.8-0.20.70.3-0.40.40.40.4-1.1-0.6-0.6-0.6-1.11.10.4-1.30.40.31.21.2-0.41.21.3-1.0-1.31.3
Incentive Sensitization - Responses0.90.93.00.5-0.3-0.2-0.40.40.40.4-0.9-1.40.10.1-1.11.11.0-1.11.01.01.11.1-0.31.41.3-1.3-1.51.7
Incentive Sensitization - Breakpoint1.21.23.20.2-0.00.0-0.60.60.60.6-1.1-1.3-0.2-0.2-1.41.41.0-1.41.01.01.41.40.01.61.5-1.5-1.81.8
Sum of active levers in priming session hrs 5-63.02.97.52.2-1.8-1.62.2-2.2-2.2-2.21.8-2.02.12.11.3-1.21.71.51.71.6-1.2-1.2-2.7-0.8-1.40.10.60.4
Progressive ratio1.21.44.11.5-1.1-0.91.4-1.4-1.4-1.41.2-1.41.41.40.8-0.81.41.01.41.4-0.7-0.7-2.0-0.5-1.00.10.50.5
Food seeking constrained by brief footshock7.39.015.33.8-3.4-3.33.6-3.6-3.6-3.63.7-2.23.23.22.9-3.31.43.31.41.3-3.2-3.2-3.9-2.7-3.21.62.60.1
Seeking ratio, punishment vs. effort0.30.41.00.6-0.9-1.00.5-0.5-0.5-0.50.60.00.10.10.6-0.8-0.70.5-0.7-0.7-0.8-0.80.2-0.7-0.40.80.5-0.2
Retroperitoneal fat weight0.20.82.50.30.0-0.2-0.20.20.20.2-1.0-1.0-0.7-0.7-1.01.10.6-1.20.60.51.11.10.11.31.4-1.0-1.61.5
Reaction time number correct1.52.23.81.9-2.0-1.71.9-1.9-1.9-1.91.8-1.21.21.21.6-1.60.81.70.80.8-1.5-1.5-1.1-1.2-1.50.91.0-0.2
Reaction time mean minus median0.91.24.3-1.71.21.1-1.21.21.21.2-0.42.10.10.10.1-0.2-1.8-0.0-1.8-1.8-0.2-0.21.0-0.6-0.20.80.9-1.4
Reaction time mean minus median AUC0.40.62.0-1.00.70.5-0.90.90.90.9-0.41.20.50.5-0.10.0-1.4-0.2-1.4-1.4-0.0-0.00.3-0.30.20.50.4-0.7
Reaction time num false alarms0.10.10.3-0.40.50.2-0.30.30.30.3-0.40.40.30.3-0.20.3-0.5-0.5-0.5-0.50.30.3-0.00.30.40.1-0.4-0.2
Reaction time num false alarms AUC0.20.20.7-0.40.50.2-0.40.40.40.4-0.70.10.40.4-0.50.6-0.2-0.8-0.2-0.20.60.6-0.20.60.7-0.3-0.80.1
Reaction time trials correct on left1.52.23.81.9-2.0-1.71.9-1.9-1.9-1.91.8-1.21.21.21.6-1.60.81.70.80.8-1.5-1.5-1.1-1.2-1.50.91.0-0.2
Reaction time trials on left1.42.13.71.9-1.9-1.61.9-1.9-1.9-1.91.8-1.31.31.31.5-1.50.91.60.90.9-1.4-1.4-1.2-1.1-1.40.80.9-0.1
Reaction time mean0.81.13.5-1.51.10.9-1.21.21.21.2-0.51.9-0.6-0.6-0.1-0.0-1.7-0.2-1.7-1.7-0.1-0.11.4-0.40.10.70.6-1.0
Reaction time mean AUC0.91.24.2-1.51.10.9-1.11.11.11.1-0.32.0-0.5-0.50.2-0.2-1.9-0.0-1.9-1.9-0.3-0.31.3-0.7-0.10.90.9-1.3
Median of all reaction times0.50.71.9-1.10.90.7-1.01.01.01.0-0.51.4-0.9-0.9-0.20.1-1.2-0.3-1.2-1.20.10.11.4-0.20.20.40.3-0.6
Reaction time omissions0.71.02.1-1.01.21.4-1.11.11.11.1-1.10.20.10.1-1.21.21.0-1.01.01.01.21.2-0.11.10.6-1.5-0.80.6
Reaction time false alarm rate0.71.02.0-1.01.10.8-1.21.21.21.2-1.30.5-0.2-0.2-1.11.2-0.4-1.4-0.4-0.41.21.20.31.11.3-0.7-1.20.4
Reaction time premature initiation rate0.50.73.51.4-1.7-1.90.8-0.8-0.8-0.80.6-1.10.60.60.5-0.6-0.40.4-0.5-0.5-0.6-0.6-0.5-0.30.20.8-0.00.6
Reaction time premature initiations1.62.27.22.4-2.6-2.71.8-1.8-1.8-1.81.5-1.81.31.31.3-1.40.11.20.0-0.0-1.4-1.4-1.1-0.9-0.61.30.50.5
Std. dev. reaction times0.60.82.9-1.20.90.7-0.80.80.80.8-0.21.70.10.10.3-0.3-1.60.1-1.6-1.6-0.3-0.30.9-0.7-0.30.90.9-1.2
Reaction time trials completed1.42.13.71.9-1.9-1.61.9-1.9-1.9-1.91.8-1.31.31.31.5-1.50.91.60.90.9-1.4-1.4-1.2-1.1-1.40.80.9-0.1
Reaction time trials AUC1.52.23.71.9-1.9-1.61.9-1.9-1.9-1.91.8-1.21.31.31.6-1.50.91.71.00.9-1.5-1.5-1.1-1.2-1.60.81.0-0.2
Run reversals in cocaine runway, females1.00.94.7-0.00.61.1-0.30.30.30.3-0.2-0.80.60.6-0.70.82.1-0.32.12.20.80.8-0.00.9-0.0-1.6-0.60.9
Run reversals in cocaine runway, males0.80.82.3-0.30.2-0.00.2-0.2-0.2-0.20.51.10.40.40.9-0.9-1.50.6-1.5-1.5-0.9-0.9-0.1-1.1-0.61.31.0-1.4
Latency to leave start box in cocaine runway0.91.02.30.1-0.3-0.20.7-0.7-0.7-0.71.20.71.01.01.3-1.2-0.41.4-0.4-0.4-1.3-1.3-0.5-1.4-1.51.11.5-1.3
Latency to leave start box in cocaine runway, F0.80.81.60.2-0.5-0.70.7-0.7-0.7-0.71.00.61.01.01.2-1.1-0.91.0-0.9-0.8-1.1-1.1-0.4-1.2-1.01.21.2-1.3
Latency to leave start box in cocaine runway, M0.30.31.6-0.50.81.3-0.60.60.60.60.00.4-0.1-0.1-0.20.20.80.20.80.90.20.20.10.1-0.5-0.50.3-0.1
Std. dev. time between licks in bursts3.33.99.4-2.73.03.1-2.42.42.42.4-2.02.0-2.3-2.3-1.71.9-0.2-1.7-0.1-0.11.91.92.51.51.2-1.3-1.2-0.7
Total sessions with >9 infusions0.20.30.90.20.40.3-0.20.20.20.2-0.6-0.6-0.1-0.1-0.70.60.3-0.70.30.30.60.6-0.20.70.8-0.5-0.91.0
Short access day 1 total inactive lever presses0.80.92.1-0.80.90.6-0.80.80.80.8-1.40.1-0.6-0.6-1.31.40.0-1.50.00.01.41.40.21.31.5-0.9-1.40.8
Short access day 10 total inactive lever presses0.30.41.0-0.0-0.2-0.1-0.20.20.20.2-0.7-0.6-0.5-0.5-0.60.80.5-0.80.50.50.80.80.70.90.9-0.6-1.00.7
Short access day 1 total infusions0.10.10.80.6-0.1-0.10.0-0.0-0.0-0.0-0.1-0.70.40.4-0.20.10.2-0.20.20.10.10.1-0.40.20.4-0.1-0.40.9
Short access day 10 total infusions0.40.41.1-1.00.80.9-1.11.11.11.1-0.60.90.20.2-0.40.5-0.3-0.5-0.3-0.30.50.50.60.30.3-0.2-0.1-0.3
Short access total infusions0.50.61.1-0.20.70.6-0.80.80.80.8-0.9-0.3-0.2-0.2-1.01.00.4-1.00.40.31.01.00.31.01.0-0.8-1.11.1
Short access day 1 locomotion0.80.92.6-1.31.21.1-1.21.21.21.2-0.71.3-1.0-1.0-0.40.3-1.2-0.6-1.2-1.20.30.31.60.00.40.20.1-0.6
Short access day 10 total locomotion1.21.32.4-1.41.51.4-1.61.61.61.6-1.30.8-0.9-0.9-1.21.2-0.3-1.3-0.3-0.31.21.20.91.01.1-0.9-0.80.3
Short access total locomotion2.22.33.8-1.72.01.7-1.81.81.81.8-1.90.8-1.5-1.5-1.71.7-0.4-1.8-0.4-0.41.71.71.21.51.6-1.2-1.30.6
One hour access (0.3 mA shock)0.10.20.8-0.10.40.10.1-0.1-0.1-0.1-0.2-0.20.70.7-0.20.30.5-0.30.50.50.30.3-0.90.30.1-0.5-0.20.5
Compulsive drug intake0.40.41.7-1.21.00.5-0.10.10.10.1-0.51.3-0.6-0.60.00.2-0.9-0.3-0.9-0.90.20.20.6-0.00.20.30.1-0.9
One hour access (shock baseline)0.30.41.40.9-0.6-0.40.2-0.2-0.2-0.20.7-0.81.21.20.4-0.50.70.50.70.7-0.5-0.5-0.9-0.4-0.6-0.00.40.5
Social response proportion2.02.15.82.4-2.4-2.21.5-1.5-1.5-1.51.4-2.11.91.90.9-1.11.21.11.21.1-1.0-1.0-1.7-0.6-0.80.40.51.3
Social responses0.50.72.40.6-0.4-0.1-0.10.10.10.1-0.2-1.21.11.1-0.50.51.5-0.31.51.50.60.6-0.80.80.3-1.0-0.61.3
Social time0.50.71.9-1.31.41.4-0.90.90.90.9-1.01.00.20.2-0.70.9-0.3-0.8-0.3-0.30.90.90.70.70.7-0.4-0.5-0.3
Soleus weight3.510.218.42.1-2.2-1.83.6-3.6-3.6-3.64.10.23.73.74.0-3.80.14.20.10.1-3.8-3.8-2.3-3.8-4.32.93.8-2.5
Bone: stiffness0.50.72.6-0.40.2-0.4-0.60.60.60.6-0.90.5-1.1-1.1-0.60.4-1.6-0.9-1.6-1.60.40.41.10.41.30.5-0.7-0.0
Tibialis anterior weight3.612.426.31.4-2.4-3.13.1-3.1-3.1-3.13.51.72.72.74.4-4.4-3.93.6-3.9-3.9-4.4-4.4-1.1-4.5-3.25.13.9-3.7
Time to tail flick, vehicle, before self-admin1.01.12.2-0.71.01.0-0.90.90.90.9-1.1-0.1-1.1-1.1-1.11.30.4-1.30.50.51.31.30.71.31.2-1.2-1.50.7
Time to tail flick, vehicle, after self-admin2.32.54.72.2-1.7-2.02.2-2.2-2.2-2.21.8-1.31.81.81.7-1.60.11.30.10.1-1.6-1.6-1.6-1.3-1.11.30.90.2
Time to tail flick, test, before self-admin0.80.72.3-1.21.01.3-1.11.11.11.1-0.90.8-1.0-1.0-0.70.8-0.1-0.7-0.1-0.10.80.81.50.60.5-0.5-0.5-0.1
Time to tail flick, test, after self-admin2.32.34.9-0.00.70.6-0.80.80.80.8-1.6-1.3-1.0-1.0-1.81.91.7-1.81.71.62.02.00.72.11.8-2.2-2.22.1
Delta time to tail flick, vehicle, before/after SA2.01.93.41.8-1.7-1.61.7-1.7-1.7-1.71.6-1.11.81.81.4-1.40.61.40.60.6-1.4-1.4-1.3-1.1-1.21.01.00.2
Delta time to tail flick, test, before/after SA1.11.03.81.2-0.7-0.90.6-0.6-0.6-0.6-0.3-1.90.30.3-0.60.71.4-0.61.41.40.70.7-0.91.10.9-1.1-1.31.8
Tibia length6.016.828.1-4.54.43.9-5.05.05.05.0-5.12.3-5.3-5.3-4.44.4-1.6-4.7-1.6-1.64.34.34.43.74.4-2.6-3.40.8
Ambulatory time before self-admin0.70.72.1-0.4-0.0-0.00.1-0.1-0.1-0.10.81.20.30.30.9-1.0-0.91.1-0.8-0.8-1.0-1.0-0.0-1.2-1.21.01.4-1.4
Ambulatory time after self-admin2.83.04.81.3-1.6-2.01.8-1.8-1.8-1.81.9-0.01.81.82.0-2.2-1.02.0-1.1-1.1-2.2-2.2-1.8-2.1-1.81.92.0-1.0
Bone: tissue strength0.70.72.0-1.11.11.0-0.80.80.80.8-0.90.8-1.4-1.4-0.70.7-0.4-0.8-0.4-0.40.70.71.00.50.6-0.4-0.4-0.2
Total heroin consumption0.81.02.50.2-0.5-0.40.9-0.9-0.9-0.91.30.50.60.61.5-1.2-0.21.3-0.1-0.1-1.2-1.2-0.0-1.3-1.60.91.5-1.2
Bone: trabecular number0.71.12.8-0.91.41.7-0.90.90.90.9-1.00.2-0.3-0.3-1.21.31.3-0.91.31.31.31.30.11.20.7-1.5-1.00.6
Bone: trabecular spacing0.81.02.40.6-0.9-1.11.0-1.0-1.0-1.01.00.30.10.11.3-1.3-1.21.0-1.2-1.2-1.3-1.30.2-1.3-0.81.51.1-0.9
Bone: trabecular thickness0.50.61.8-0.91.21.4-0.70.70.70.7-0.80.5-0.6-0.6-0.81.00.6-0.70.70.71.01.00.50.90.5-1.0-0.70.1
Bone: trabecular tissue density1.01.42.80.4-0.5-0.71.3-1.3-1.3-1.31.30.80.80.81.7-1.5-0.91.3-0.9-0.9-1.5-1.50.1-1.5-1.31.71.3-1.6
Water consumed over 24 hours0.30.42.1-0.3-0.1-0.4-0.30.30.30.3-0.20.6-0.3-0.30.1-0.2-1.4-0.2-1.4-1.5-0.2-0.20.5-0.30.30.80.0-0.5
Number of responses in last shaping day0.30.31.2-0.1-0.10.7-0.90.90.90.90.30.30.80.80.2-0.3-0.00.40.00.0-0.3-0.31.1-0.3-0.50.20.4-0.5