Hub : Genes

Fndc3a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver isoform ratio XM_006252298.5 0.03 0.02 4.6e-03 0.01 0.01 0.01 0.01 1.2e-02 1.2e-02 3.1e-02 3.0e-02
2 Liver alternative TSS XM_006252298.5 0.03 0.02 6.7e-03 0.01 0.01 0.01 0.01 1.6e-02 1.4e-02 4.6e-02 2.3e-02
3 Liver intron excision ratio chr15_54165210_54168980 0.03 0.02 4.0e-03 0 0.01 -0 0 2.0e-01 3.0e-02 5.3e-01 1.8e-01
4 pVTA gene expression Fndc3a 0.07 0.04 2.4e-05 0.02 0.04 0.04 0.04 5.8e-03 2.6e-04 2.8e-04 4.8e-04
5 IC gene expression Fndc3a 0.11 0.06 1.3e-04 0.11 0.1 0.1 0.1 2.0e-05 6.3e-05 4.9e-05 7.6e-05
6 Liver alternative TSS XM_039093358.1 0.04 0.03 1.1e-03 0.02 0.02 0.01 0.02 1.3e-03 2.1e-03 3.5e-02 2.3e-03
7 Liver isoform ratio XM_039093358.1 0.04 0.03 1.1e-03 0.03 0.02 0.01 0.02 7.9e-04 1.3e-03 1.4e-02 1.4e-03
8 Liver alternative TSS XM_039093358.1 0.05 0.03 1.1e-04 0.03 0.03 0.03 0.03 9.2e-05 1.5e-04 4.1e-04 9.7e-05
9 NAcc gene expression Fndc3a 0.12 0.05 0.0e+00 0.11 0.11 0.11 0.11 2.9e-16 3.1e-16 3.6e-16 1.9e-16
10 BLA alternative TSS XM_006252298.5 0.22 0.16 7.1e-03 -0 0.04 0.06 0.02 4.5e-01 2.5e-03 4.5e-04 1.8e-02
11 Adipose mRNA stability Fndc3a 0.04 0.03 1.3e-04 0.03 0.03 0.03 0.03 2.1e-04 7.7e-04 3.0e-04 1.9e-04
12 BLA alternative TSS XM_006252298.5 0.23 0.16 6.1e-03 -0 0.04 0.06 0.03 4.3e-01 2.3e-03 5.1e-04 1.5e-02
13 Adipose alternative TSS NM_001412039.1 0.03 0.02 3.4e-03 0 0.02 0.01 0.01 1.4e-01 4.9e-03 2.6e-02 6.8e-02
14 Adipose alternative TSS NM_001412039.1 0.03 0.02 3.2e-03 0 0.02 0.01 0.01 1.2e-01 4.1e-03 2.3e-02 5.9e-02
15 Brain gene expression Fndc3a 0.15 0.07 2.6e-12 0.12 0.14 0.14 0.14 2.1e-11 7.8e-13 3.0e-13 3.3e-13
16 Liver mRNA stability Fndc3a 0.02 0.02 4.2e-03 0.01 0 0 0 1.0e-02 8.0e-02 1.6e-01 7.5e-02
17 Adipose isoform ratio NM_001412039.1 0.03 0.02 5.1e-03 0 0.02 0.01 0.01 1.4e-01 5.2e-03 1.8e-02 4.8e-02
18 NAcc mRNA stability Fndc3a 0.03 0.02 5.5e-04 0.01 0.02 0.01 0.01 3.1e-02 1.6e-03 2.3e-03 1.3e-02
19 PL gene expression Fndc3a 0.1 0.06 9.4e-09 0.07 0.08 0.08 0.08 1.8e-08 3.9e-09 3.7e-09 6.0e-09
20 BLA gene expression Fndc3a 0.24 0.12 2.2e-08 0.11 0.13 0.12 0.12 2.7e-06 2.5e-07 1.0e-06 3.7e-07
21 Adipose gene expression Fndc3a 0.19 0.1 4.2e-11 0.05 0.09 0.08 0.07 1.8e-06 4.8e-10 2.1e-09 1.4e-08
22 BLA intron excision ratio chr15_54156388_54165134 0.23 0.15 5.7e-04 0.05 0.05 0.06 0.06 1.3e-03 7.6e-04 6.2e-04 2.3e-04
23 Liver gene expression Fndc3a 0.4 0.16 0.0e+00 0.17 0.29 0.28 0.28 3.6e-18 5.1e-32 6.2e-31 1.9e-31

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.20.42.00.60.5-0.70.7-0.40.40.40.40.4-1.1-1.4-1.10.60.6-0.40.40.60.7-0.30.0-0.1-1.1-0.1
Area under the delay curve0.30.51.51.01.0-1.01.0-0.60.70.70.70.51.0-0.61.00.30.3-0.41.20.30.2-0.20.20.20.3-0.8
BMI with tail0.20.63.4-0.6-0.51.0-1.00.1-0.0-0.0-0.10.01.51.81.5-0.3-0.2-0.3-0.9-0.2-0.3-0.20.60.80.70.9
BMI without tail0.10.83.3-1.2-1.21.5-1.50.6-0.6-0.6-0.6-0.5-0.21.5-0.2-0.2-0.2-0.3-1.8-0.1-0.1-0.30.30.5-0.21.5
Body weight0.20.96.00.40.6-0.10.2-0.70.80.80.80.72.41.32.40.20.2-0.50.40.2-0.0-0.51.01.11.10.1
Weight adjusted by age0.20.61.8-0.10.1-0.10.20.4-0.2-0.2-0.2-0.60.90.60.8-0.9-0.91.00.9-0.9-1.01.0-0.7-0.81.4-1.2
Bone surface0.30.62.11.01.0-1.21.2-0.70.70.70.70.7-0.4-1.4-0.40.70.7-0.41.00.60.7-0.30.20.0-0.7-0.6
Bone volume0.20.42.10.80.7-1.01.0-0.40.40.40.40.3-0.8-1.4-0.80.40.4-0.10.90.40.4-0.1-0.1-0.3-0.6-0.7
Breakpoint value in progressive ratio session0.81.53.0-1.1-1.10.7-0.71.3-1.4-1.4-1.4-1.6-1.10.4-1.1-1.4-1.41.4-0.1-1.4-1.41.5-1.7-1.70.5-0.8
Number of licking bursts0.10.30.9-0.2-0.20.4-0.4-0.20.10.10.10.30.70.50.60.40.4-0.7-0.70.40.4-0.70.70.8-0.40.9
Context. condit. distance diff. score1.82.29.5-2.0-2.02.5-2.50.9-1.0-1.0-1.0-0.6-1.01.6-1.0-0.0-0.0-0.6-3.10.20.3-0.80.50.9-1.12.9
Locomotion velocity, session 10.50.61.7-0.2-0.2-0.20.10.7-0.6-0.6-0.6-0.8-0.6-0.2-0.6-0.9-0.91.00.5-1.0-0.91.2-1.2-1.30.6-1.2
Locomotion distance, session 10.50.62.21.11.1-1.41.4-0.50.60.60.70.4-0.2-1.5-0.20.30.30.11.40.20.20.1-0.2-0.4-0.1-1.3
Locomotion velocity, session 20.40.41.41.00.9-1.21.2-0.60.50.50.50.5-0.1-1.2-0.10.40.4-0.11.10.30.30.0-0.1-0.2-0.2-0.9
Locomotion distance, session 21.21.76.11.81.8-2.32.3-0.90.90.90.90.6-0.6-2.4-0.50.40.40.32.50.20.30.5-0.5-0.80.1-2.3
Locomotion velocity, session 30.50.62.6-1.0-0.91.2-1.20.5-0.5-0.5-0.5-0.40.71.60.6-0.5-0.40.0-1.1-0.4-0.4-0.10.10.30.40.9
Locomotion distance, session 30.30.31.6-0.7-0.70.9-0.90.1-0.3-0.3-0.30.0-0.10.7-0.10.10.2-0.4-1.20.20.3-0.50.50.6-0.41.3
Stereotopy head waving bouts, day 30.60.71.5-0.5-0.50.3-0.30.8-0.8-0.8-0.8-0.9-0.20.6-0.2-1.0-1.01.20.4-1.1-1.11.2-1.0-1.01.1-0.8
Stereotopy head waving duration, day 30.91.13.5-0.4-0.30.2-0.10.8-0.8-0.8-0.8-1.00.91.00.9-1.3-1.31.40.8-1.4-1.51.4-1.1-1.11.9-1.3
Locomotion velocity, session 73.03.315.8-1.7-1.82.4-2.50.2-0.3-0.3-0.30.3-1.41.3-1.41.01.0-1.6-3.71.21.3-1.81.51.9-2.24.0
Locomotion distance, session 72.12.611.3-1.6-1.72.1-2.20.4-0.6-0.6-0.6-0.0-2.00.8-2.00.70.7-1.1-3.40.91.1-1.31.01.2-2.23.3
Stereotopy head waving bouts, day 70.50.63.80.60.7-0.60.7-0.40.50.50.50.31.90.41.9-0.1-0.10.11.1-0.2-0.30.10.10.11.2-0.9
Stereotopy head waving duration, day 70.60.74.10.20.4-0.30.3-0.10.10.10.1-0.12.00.82.0-0.6-0.60.41.0-0.6-0.70.5-0.2-0.11.6-1.0
Locomotion velocity, session 80.20.21.2-0.6-0.60.7-0.80.2-0.2-0.2-0.2-0.1-0.20.6-0.2-0.0-0.0-0.3-1.10.00.1-0.20.20.3-0.40.9
Locomotion distance, session 80.30.51.20.40.3-0.20.2-0.60.60.60.60.7-0.5-0.8-0.50.90.9-0.9-0.40.91.0-0.90.80.8-1.10.8
Degree of sensitization distance1.31.45.9-1.0-1.11.2-1.20.4-0.5-0.5-0.5-0.2-2.4-0.2-2.40.50.5-0.5-2.10.60.8-0.60.30.3-1.91.9
Degree of sensitization stereotypy0.40.53.60.40.5-0.30.4-0.50.50.50.50.41.90.61.90.00.0-0.20.6-0.0-0.1-0.20.40.40.9-0.4
Conditioned locomotion0.30.40.8-0.9-0.90.9-0.90.8-0.7-0.7-0.7-0.7-0.70.5-0.7-0.4-0.40.3-0.9-0.3-0.30.2-0.3-0.3-0.10.6
Cocaine response after cond. corrected1.82.64.1-2.0-2.01.9-1.91.9-2.0-2.0-2.0-1.9-1.51.5-1.5-1.6-1.61.5-1.3-1.5-1.41.4-1.5-1.40.50.4
Cocaine response after cond. not corrected0.60.81.5-1.2-1.21.2-1.21.1-1.1-1.1-1.1-1.0-0.61.1-0.6-0.9-0.90.7-0.9-0.8-0.80.7-0.7-0.60.30.4
Cocaine response before conditioning3.23.95.62.22.2-1.91.9-2.42.32.32.32.32.3-1.32.32.02.0-2.01.31.91.8-2.02.12.0-0.70.0
Saline control response0.60.81.91.21.2-1.31.3-1.00.80.80.81.00.5-1.40.40.90.9-0.71.00.80.8-0.70.60.4-0.5-0.5
Bone: connectivity density0.71.13.20.80.6-0.70.6-0.90.90.90.91.0-1.0-1.5-1.01.31.3-1.2-0.11.31.4-1.20.80.8-1.80.7
Bone: cortical apparent density0.91.44.0-1.7-1.71.8-1.91.3-1.1-1.1-1.1-1.1-1.11.4-1.1-0.7-0.70.4-2.0-0.6-0.50.4-0.5-0.3-0.31.3
Bone: cortical area0.20.20.80.70.7-0.80.8-0.50.40.40.40.50.2-0.80.20.40.4-0.20.90.30.3-0.30.20.1-0.1-0.5
Bone: cortical porosity2.32.57.41.82.0-1.71.8-1.71.71.71.71.62.7-0.52.71.11.1-1.11.81.00.8-1.11.41.30.7-0.8
Bone: cortical porosity1.82.04.51.81.9-1.81.8-1.61.51.51.51.42.1-0.82.10.90.9-0.81.90.80.7-0.81.00.90.6-1.0
Bone: cortical thickness0.20.30.50.60.5-0.50.5-0.60.60.60.60.60.4-0.40.40.70.7-0.60.30.60.6-0.70.60.6-0.40.2
Bone: cortical thickness0.40.51.4-1.0-1.01.1-1.20.6-0.7-0.7-0.7-0.5-0.70.7-0.7-0.3-0.30.2-1.2-0.2-0.20.1-0.1-0.0-0.21.0
Bone: cortical tissue density1.01.54.6-1.8-1.81.9-2.01.3-1.2-1.2-1.2-1.1-1.11.5-1.2-0.7-0.70.4-2.1-0.6-0.50.3-0.5-0.3-0.41.5
Condit. Reinf. active minus inactive responses0.80.92.61.21.2-1.11.1-1.01.21.21.20.91.6-0.41.60.60.6-0.51.10.60.5-0.50.80.70.4-0.6
Condit. Reinf. active-inactive response ratio0.40.51.6-0.5-0.40.5-0.50.6-0.5-0.5-0.5-0.60.81.10.7-0.8-0.80.80.1-0.8-0.90.7-0.5-0.41.3-0.3
Condit. Reinf. active responses2.22.84.52.02.0-1.81.8-2.02.12.12.11.92.0-1.12.01.61.6-1.51.31.51.4-1.41.71.6-0.3-0.3
Condit. Reinf. inactive responses4.15.37.52.72.7-2.62.6-2.72.72.72.72.71.1-2.51.12.52.5-2.41.42.42.4-2.22.11.9-1.7-0.1
Incentive salience index mean4.05.212.72.52.7-2.22.2-2.62.82.82.82.53.6-0.83.51.91.9-2.01.81.81.6-1.92.32.30.2-0.4
Condit. Reinf. lever presses6.19.118.53.23.4-2.72.8-3.53.63.63.63.44.3-1.34.32.82.8-3.01.92.72.5-2.93.33.2-0.40.0
Condit. Reinf. active minus inactive responses0.30.40.70.50.5-0.40.4-0.60.60.60.60.6-0.4-0.7-0.30.80.8-0.7-0.00.80.8-0.80.70.7-0.80.5
Condit. Reinf. active-inactive response ratio0.00.10.2-0.0-0.00.1-0.1-0.10.20.20.20.10.10.30.10.20.2-0.3-0.30.20.2-0.30.40.4-0.10.4
Condit. Reinf. active responses0.50.81.40.70.6-0.50.5-0.90.80.80.80.9-0.3-0.9-0.31.11.1-1.0-0.11.21.2-1.11.01.0-1.10.7
Condit. Reinf. inactive responses0.71.11.90.90.8-0.80.8-1.21.01.01.01.2-0.2-1.3-0.21.41.4-1.30.01.41.4-1.31.11.1-1.30.7
Condit. Reinf. lever presses2.33.45.02.12.2-1.91.9-2.22.12.12.12.12.2-1.42.21.81.8-1.91.31.71.6-1.71.81.7-0.5-0.2
Condit. Reinf. lever reinforcers received0.81.11.80.90.9-0.70.7-1.21.11.11.11.20.3-0.90.31.31.3-1.30.11.31.3-1.31.31.3-1.00.7
Conditioned reinforcement - actives0.20.62.3-0.8-1.00.9-0.90.6-0.7-0.7-0.8-0.5-1.5-0.2-1.5-0.1-0.1-0.3-1.30.00.1-0.2-0.3-0.3-1.21.0
Conditioned reinforcement - inactives1.54.16.02.22.1-2.02.0-2.32.22.22.12.30.2-2.30.22.42.4-2.30.82.42.4-2.32.01.8-2.10.5
Conditioned locomotion0.10.10.50.20.1-0.40.40.0-0.2-0.2-0.2-0.1-0.3-0.7-0.3-0.1-0.1-0.10.4-0.1-0.10.1-0.5-0.6-0.4-0.5
Patch foraging indifference point 0 sec2.67.39.73.13.0-2.72.7-3.13.13.13.03.11.5-2.51.53.13.1-3.11.23.02.9-2.82.92.7-2.10.4
Patch foraging indifference point AUC0.71.72.6-1.6-1.61.5-1.41.6-1.4-1.4-1.4-1.6-1.31.1-1.2-1.3-1.31.5-0.8-1.3-1.31.3-1.2-1.10.80.1
Delay disc. indifference point, 0s delay0.91.13.01.51.5-1.71.7-0.90.90.90.90.80.5-1.70.50.70.7-0.71.60.60.6-0.40.2-0.0-0.6-1.2
Delay disc. indifference point, 16s delay0.20.21.00.60.6-0.80.8-0.10.20.20.20.00.0-1.00.00.10.1-0.20.90.10.1-0.1-0.3-0.4-0.3-0.8
Delay disc. indifference point, 2s delay0.50.52.10.40.5-0.60.70.2-0.1-0.1-0.1-0.31.00.21.0-0.6-0.60.61.3-0.7-0.80.8-0.6-0.71.1-1.4
Delay disc. indifference point, 24s delay0.10.10.4-0.4-0.40.4-0.40.4-0.3-0.3-0.3-0.40.20.60.3-0.4-0.40.3-0.1-0.4-0.40.3-0.3-0.20.60.0
Delay disc. indifference point, 4s delay0.30.42.2-0.00.1-0.10.10.2-0.2-0.2-0.2-0.30.60.80.6-0.6-0.60.80.7-0.7-0.80.8-0.4-0.41.5-0.8
Delay disc. indifference point, 8s delay0.30.50.70.80.8-0.70.7-0.80.80.80.80.80.7-0.60.70.70.7-0.80.50.70.7-0.80.70.7-0.4-0.0
Indifference point function ln k0.92.64.71.71.7-1.41.4-1.91.81.81.81.92.2-0.62.11.61.6-1.80.61.61.4-1.71.81.8-0.50.2
Indifference point function log k0.92.64.71.71.7-1.41.4-1.91.81.81.81.92.2-0.62.11.61.6-1.80.61.61.4-1.71.81.8-0.50.2
Patch foraging total patch changes 0 sec2.36.69.03.03.0-2.72.7-3.02.92.92.93.01.5-2.51.52.92.9-2.81.32.82.7-2.62.72.5-1.90.2
Patch foraging total patch changes 12 sec1.11.53.21.61.5-1.61.6-1.31.41.41.41.3-0.1-1.8-0.11.31.3-0.91.11.21.2-0.80.90.7-0.9-0.4
Patch foraging total patch changes 18 sec0.20.41.70.30.2-0.20.2-0.30.30.30.30.4-0.9-0.9-0.80.70.7-0.7-0.30.80.8-0.70.50.4-1.30.6
Patch foraging total patch changes 24 sec0.51.62.71.51.6-1.41.5-1.41.41.41.41.31.6-1.11.61.11.1-1.11.21.11.0-1.01.21.1-0.1-0.4
Patch foraging total patch changes 6 sec0.81.32.90.60.6-0.20.3-1.11.11.11.01.21.1-0.21.11.31.3-1.6-0.41.41.3-1.61.71.7-1.01.3
Patch foraging time to switch 0 sec0.00.10.60.20.2-0.30.3-0.10.10.10.10.2-0.7-0.7-0.70.30.3-0.30.10.30.3-0.2-0.1-0.2-0.8-0.1
Patch foraging water rate 0 sec0.10.41.10.60.6-0.40.5-0.70.70.70.70.61.0-0.01.00.50.5-0.50.30.50.4-0.60.80.80.20.1
Patch foraging water rate 12 sec0.00.10.9-0.00.00.1-0.00.1-0.0-0.00.0-0.10.90.20.8-0.1-0.1-0.10.1-0.1-0.2-0.10.10.10.3-0.0
Patch foraging water rate 18 sec0.30.73.4-0.9-0.81.1-1.00.6-0.6-0.6-0.6-0.61.41.81.3-0.7-0.70.4-0.6-0.7-0.80.30.00.21.30.4
Patch foraging water rate 24 sec0.40.51.9-1.0-1.01.3-1.30.5-0.6-0.6-0.6-0.50.11.30.0-0.3-0.3-0.1-1.4-0.2-0.2-0.20.20.3-0.01.2
Patch foraging water rate 6 sec0.30.51.6-0.1-0.0-0.00.10.4-0.5-0.5-0.6-0.51.00.50.9-0.8-0.80.70.7-0.9-1.00.8-0.7-0.71.3-1.0
Seeking ratio, delayed vs. immediate footshock0.40.61.80.80.8-0.80.8-1.00.60.60.60.8-0.3-1.4-0.40.90.9-0.80.30.90.9-0.80.60.5-1.10.1
Distance traveled before self-admin0.51.03.60.10.2-0.60.60.6-0.6-0.6-0.6-0.90.0-0.2-0.1-1.1-1.11.51.4-1.2-1.21.4-1.4-1.51.1-1.9
Distance traveled after self-admin1.83.24.8-1.7-1.61.4-1.42.0-2.0-2.0-2.0-2.1-0.21.9-0.2-2.2-2.22.1-0.3-2.2-2.22.1-2.0-1.81.9-0.8
Extensor digitorum longus weight5.120.449.0-2.9-2.52.1-1.94.2-4.1-4.1-4.1-4.62.44.52.3-5.8-5.85.72.0-5.9-6.25.8-4.9-4.87.0-4.4
Bone: elastic displacement0.40.52.20.80.7-1.11.0-0.30.30.30.30.2-1.2-1.5-1.20.30.30.11.00.20.30.3-0.4-0.6-0.5-1.0
Bone: elastic work1.11.44.61.71.6-2.12.1-0.90.90.90.90.7-0.5-2.1-0.50.50.50.02.10.40.40.2-0.3-0.6-0.3-1.8
Bone: endosteal estimation0.10.21.00.60.7-0.70.7-0.40.40.40.40.30.6-0.20.70.00.00.21.0-0.0-0.10.20.0-0.00.6-0.8
Bone: endosteal perimeter0.10.31.40.70.8-0.90.9-0.40.40.40.40.30.6-0.50.60.00.00.21.2-0.1-0.10.2-0.1-0.20.5-1.0
Epididymis fat weight0.42.03.21.41.3-1.21.1-1.61.51.51.51.6-0.5-1.6-0.41.81.8-1.60.21.81.8-1.51.51.4-1.70.7
Delta time in closed arm before/after self-admin1.81.73.31.31.2-1.21.2-1.41.21.21.21.4-0.6-1.7-0.71.61.6-1.40.21.61.7-1.51.21.0-1.80.5
Delta time in open arm before/after self-admin0.10.10.2-0.3-0.20.3-0.30.2-0.1-0.1-0.1-0.30.30.40.3-0.4-0.40.3-0.0-0.4-0.40.3-0.3-0.20.4-0.1
Diff in mean of infusions in LGA sessions0.40.81.4-0.8-0.70.6-0.60.8-0.9-0.9-0.9-0.9-0.11.0-0.2-1.1-1.11.2-0.0-1.1-1.11.1-1.0-0.91.1-0.6
Delay discount exponential model param0.30.51.7-0.8-0.90.9-0.90.5-0.6-0.6-0.6-0.4-1.20.2-1.3-0.2-0.20.2-1.2-0.1-0.00.1-0.2-0.1-0.60.9
Extinction: sum of active levers before priming0.30.41.70.70.5-0.70.7-0.40.40.40.40.4-0.7-1.3-0.70.80.8-0.60.20.70.8-0.70.20.1-1.10.0
Active lever presses in extinction session 60.10.10.6-0.3-0.30.4-0.40.10.00.00.0-0.1-0.20.2-0.20.30.3-0.5-0.80.30.3-0.40.30.3-0.60.7
Bone: final force1.11.84.81.31.3-1.01.0-1.51.61.61.61.52.2-0.22.21.21.2-1.40.81.21.1-1.41.61.60.10.3
Bone: final moment1.21.93.81.51.6-1.31.3-1.61.61.61.61.61.9-0.61.91.21.2-1.21.11.21.1-1.21.51.40.1-0.1
Food consumed during 24 hour testing period0.30.71.31.11.1-1.11.1-1.00.90.90.90.90.5-0.80.50.80.8-0.70.90.80.7-0.60.60.5-0.4-0.4
Glucose0.71.01.9-1.4-1.41.4-1.31.2-1.3-1.3-1.3-1.1-1.01.0-1.0-0.8-0.80.8-1.1-0.8-0.70.7-0.7-0.60.30.6
Heart weight0.20.30.50.50.4-0.40.4-0.60.50.50.50.6-0.3-0.6-0.30.70.7-0.6-0.10.70.7-0.50.50.4-0.60.3
Delay discount hyperbolic model param0.30.41.5-0.7-0.80.8-0.80.4-0.5-0.5-0.5-0.3-1.20.1-1.2-0.0-0.00.1-1.20.00.1-0.1-0.1-0.0-0.70.9
Intermittent access intake day 1-15 change0.31.54.20.60.5-0.40.3-0.91.01.01.11.0-0.9-1.2-0.81.61.6-1.5-0.71.61.7-1.61.41.3-2.01.4
Intermittent access intake escalation0.42.24.31.10.9-0.80.8-1.21.41.41.41.4-0.5-1.6-0.41.91.9-1.9-0.42.02.0-1.91.71.6-2.11.3
Intermittent access intake escalation 20.50.81.90.10.00.1-0.1-0.40.60.60.60.6-0.8-0.5-0.81.11.1-1.0-1.01.21.2-1.11.01.0-1.41.4
Intermitt. access day 1 inactive lever presses0.00.41.4-0.2-0.20.6-0.6-0.30.20.20.20.40.50.70.50.40.5-0.7-0.90.50.5-0.70.91.0-0.11.2
Intermitt. access day 15 inactive lever presses0.21.11.71.01.0-0.80.9-1.11.11.11.21.11.1-0.61.11.21.2-1.20.11.21.1-1.11.31.2-0.40.4
Intermitt. access escalation Index0.00.10.1-0.1-0.1-0.00.00.3-0.2-0.2-0.2-0.3-0.00.1-0.0-0.3-0.30.30.3-0.3-0.30.4-0.4-0.40.3-0.4
Intermittent access day 1 total infusions0.10.30.50.60.6-0.50.5-0.70.60.60.60.70.5-0.10.50.60.6-0.70.30.60.6-0.60.60.6-0.10.1
Intermittent access day 15 total infusions1.02.44.11.41.3-1.11.1-1.51.61.61.51.7-0.1-1.6-0.02.02.0-1.9-0.02.02.0-1.91.81.6-1.71.0
Intermittent access terminal intake (last 3 days)0.50.91.90.50.4-0.20.2-0.80.80.80.81.0-0.5-0.6-0.41.31.3-1.3-0.71.31.4-1.31.21.2-1.31.2
Intermittent access total infusions1.11.32.50.80.7-0.50.5-1.11.01.01.01.2-0.1-0.8-0.01.51.5-1.6-0.41.51.5-1.61.41.4-1.31.1
Intermittent access day 1 locomotion1.01.93.01.31.4-1.01.1-1.61.51.51.51.71.6-0.41.71.51.5-1.70.41.51.4-1.61.71.7-0.40.5
Intermittent access day 15 total locomotion0.10.20.7-0.1-0.20.3-0.3-0.10.10.10.10.2-0.5-0.1-0.50.40.4-0.6-0.70.50.5-0.50.50.5-0.70.8
Intermittent access total locomotion0.70.81.50.80.8-0.60.6-1.00.90.90.91.10.7-0.40.71.11.1-1.20.01.11.0-1.21.21.2-0.60.6
Intermittent access standard deviation0.10.52.5-0.3-0.40.1-0.10.6-0.7-0.7-0.7-0.6-1.6-0.4-1.6-0.4-0.50.80.1-0.5-0.40.7-0.9-1.0-0.3-0.4
Left kidney weight0.97.113.02.83.0-2.42.4-3.23.23.23.13.23.6-0.83.62.52.5-2.51.62.42.2-2.53.13.0-0.10.1
Right kidney weight1.28.113.53.53.7-3.33.4-3.43.43.43.43.33.6-1.93.62.42.4-2.32.82.32.1-2.12.62.40.0-1.1
Cocaine induced anxiety0.71.85.62.02.0-2.22.2-1.41.31.31.31.11.3-1.61.30.70.7-0.42.40.50.5-0.10.30.00.3-1.8
Post-drug Anxiety1.72.03.81.91.9-1.91.9-1.61.61.61.61.50.8-1.70.81.41.3-1.21.51.31.2-1.01.00.8-0.8-0.7
Baseline Anxiety0.40.73.1-0.5-0.50.8-0.8-0.10.20.20.20.3-0.30.5-0.30.70.7-1.0-1.50.80.8-1.11.01.2-1.11.8
Tail length0.21.12.41.21.1-1.21.2-1.01.11.11.11.0-0.7-1.6-0.71.21.2-0.90.61.21.2-0.90.80.6-1.10.0
Length with tail0.21.13.01.51.5-1.51.6-1.11.21.21.21.01.0-0.91.00.60.6-0.31.70.50.4-0.30.60.50.5-1.1
Length without tail0.31.46.20.30.5-0.40.50.1-0.1-0.1-0.1-0.22.21.12.2-1.0-1.01.11.6-1.1-1.31.2-0.5-0.52.5-1.7
Times rat made contact with spout1.01.12.80.30.30.1-0.1-0.90.80.80.81.10.40.00.31.31.3-1.5-1.01.31.3-1.51.61.7-1.21.6
Lifetime Intake0.70.81.70.60.5-0.40.4-0.90.80.80.81.0-0.1-0.6-0.01.21.2-1.3-0.31.21.2-1.31.11.1-1.10.9
Liver weight, left1.12.07.01.51.7-1.71.8-0.81.01.01.00.62.6-0.42.6-0.1-0.10.32.6-0.2-0.40.40.0-0.11.8-2.2
Liver weight, right0.71.22.1-0.8-0.70.5-0.51.2-1.1-1.1-1.1-1.3-0.10.7-0.1-1.4-1.41.40.4-1.4-1.41.4-1.4-1.41.2-1.0
Locomotor activity2.53.918.42.52.6-3.23.2-1.11.01.01.00.61.5-2.21.5-0.2-0.20.94.3-0.5-0.61.2-0.9-1.41.7-4.0
Locomotor testing distance1.64.014.33.03.0-3.53.5-1.71.71.71.61.40.8-3.10.80.90.9-0.23.80.70.60.1-0.1-0.50.1-3.1
Locomotor testing rearing1.45.316.13.43.4-3.93.9-2.22.22.22.21.80.9-3.31.01.41.3-0.54.01.11.0-0.30.4-0.1-0.0-3.0
Locomotion in novel chamber0.50.71.91.11.1-1.21.2-0.90.90.90.90.8-0.0-1.40.00.90.9-0.70.90.80.9-0.70.50.4-0.7-0.4
Locomotion in novel chamber post-restriction0.20.60.9-0.7-0.70.6-0.50.8-0.8-0.8-0.8-0.90.10.70.2-0.9-0.90.90.0-0.9-1.00.9-0.8-0.80.9-0.4
Fecal boli incidents, locomotor time 10.20.62.00.50.6-0.70.7-0.10.10.10.1-0.01.20.41.3-0.5-0.50.61.4-0.6-0.70.7-0.5-0.51.4-1.4
Change in fecal boli incidents, locomotor task0.20.20.3-0.5-0.50.5-0.40.4-0.5-0.5-0.5-0.4-0.20.4-0.2-0.4-0.40.4-0.3-0.4-0.40.3-0.3-0.30.30.0
Time >=10cm from walls, locomotor time 11.21.52.41.41.3-1.31.2-1.51.41.41.41.50.6-1.20.71.41.4-1.50.61.41.4-1.31.21.1-1.00.2
Bouts of movement, locomotor time 11.31.75.5-1.4-1.31.5-1.41.2-1.2-1.2-1.2-1.20.52.40.5-1.5-1.51.3-0.7-1.4-1.61.3-0.8-0.61.8-0.0
Total resting periods, locomotor time 11.82.16.1-1.6-1.51.7-1.61.4-1.4-1.4-1.4-1.40.22.50.2-1.7-1.71.5-0.9-1.6-1.71.5-1.0-0.81.90.0
Rest time, locomotor task time 11.11.72.9-1.2-1.11.0-1.01.4-1.3-1.3-1.3-1.4-0.11.5-0.1-1.7-1.71.6-0.1-1.7-1.71.6-1.4-1.41.6-0.7
Distance moved, locomotor task time 10.61.64.30.70.6-0.50.4-1.01.11.11.11.2-0.2-1.3-0.21.61.6-1.8-0.61.71.7-1.91.41.4-2.11.3
Vertical activity count, locomotor time 10.10.43.00.60.5-0.90.9-0.00.20.20.2-0.0-0.5-1.7-0.50.20.2-0.30.80.20.2-0.1-0.4-0.7-0.9-0.8
Time >=10cm from walls, locomotor time 20.30.71.6-0.5-0.40.2-0.20.8-0.7-0.7-0.7-1.00.00.50.0-1.1-1.11.10.6-1.1-1.11.2-1.2-1.21.1-1.0
Bouts of movement, locomotor time 20.93.06.0-1.9-1.71.8-1.71.8-1.8-1.8-1.8-1.90.42.40.4-2.1-2.12.0-0.5-2.1-2.21.9-1.5-1.32.3-0.4
Total resting periods, locomotor time 20.72.96.0-1.8-1.61.7-1.61.7-1.6-1.6-1.6-1.80.62.40.6-2.1-2.11.9-0.4-2.0-2.11.8-1.4-1.22.3-0.5
Rest time, locomotor task time 20.81.31.9-1.2-1.21.1-1.11.3-1.2-1.2-1.2-1.3-0.11.3-0.1-1.4-1.41.2-0.5-1.3-1.31.2-1.1-1.11.2-0.3
Distance moved, locomotor task time 21.52.04.61.41.3-1.31.3-1.31.41.41.41.3-0.1-2.2-0.11.71.7-1.80.41.71.7-1.61.21.1-2.00.4
Vertical activity count, locomotor time 20.20.52.80.40.3-0.80.80.4-0.3-0.3-0.3-0.5-0.7-1.7-0.7-0.3-0.30.31.1-0.4-0.30.5-1.0-1.3-0.5-1.3
Light reinforcement 10.52.26.40.50.3-0.10.0-1.11.01.01.01.3-1.2-1.1-1.21.81.8-1.9-1.41.92.0-2.01.71.7-2.52.0
Light reinforcement 20.81.87.9-1.6-1.71.9-2.00.8-0.8-0.8-0.8-0.4-1.90.9-1.90.20.2-0.4-2.80.40.5-0.70.40.7-1.42.5
Bone: marrow area0.10.31.00.70.8-0.80.8-0.50.50.50.50.40.6-0.30.60.10.10.11.00.10.00.10.10.00.5-0.8
Bone: maximum diameter0.20.30.5-0.5-0.50.4-0.40.6-0.6-0.6-0.6-0.60.20.60.2-0.7-0.70.70.1-0.7-0.70.6-0.6-0.60.7-0.3
Bone: maximum force0.61.33.41.41.5-1.31.4-1.21.21.21.31.11.8-0.51.80.70.7-0.71.40.70.6-0.60.90.80.5-0.7
Bone: maximum moment0.81.53.31.71.7-1.71.7-1.41.41.41.41.21.5-1.01.60.80.8-0.61.80.80.6-0.60.80.70.4-1.0
Mean time between licks in bursts0.10.83.70.50.3-0.50.5-0.40.30.30.30.4-1.9-1.6-1.90.90.9-0.5-0.10.91.0-0.60.20.1-1.60.4
Mean num. licks in bursts0.00.10.60.20.1-0.20.1-0.20.20.20.20.2-0.8-0.4-0.70.30.3-0.1-0.10.30.3-0.10.10.1-0.30.1
Cd content in liver1.21.34.80.20.2-0.70.70.7-0.7-0.7-0.4-0.9-0.2-0.5-0.1-1.1-1.21.61.7-1.3-1.31.7-1.5-1.71.5-2.2
Co content in liver5.26.18.9-2.5-2.32.1-2.12.8-2.8-2.8-2.9-2.9-0.52.4-0.5-3.0-3.02.9-0.4-3.0-3.02.9-2.6-2.52.5-1.0
Cu content in liver0.30.40.6-0.7-0.60.6-0.60.7-0.7-0.7-0.8-0.7-0.00.7-0.0-0.7-0.70.7-0.2-0.7-0.70.7-0.6-0.50.6-0.1
Fe content in liver0.60.71.50.60.5-0.50.5-0.70.80.80.70.8-1.1-1.2-1.11.11.1-0.8-0.11.11.1-0.80.80.7-1.20.6
K content in liver1.51.43.40.40.30.1-0.1-1.11.01.01.01.20.5-0.10.51.41.4-1.7-1.01.51.5-1.81.71.8-1.41.8
Mg content in liver0.60.62.40.10.00.0-0.1-0.40.30.30.30.6-1.1-0.8-1.10.90.9-0.9-0.81.01.1-1.00.70.7-1.61.1
Mn content in liver0.80.96.7-0.4-0.60.2-0.20.6-0.6-0.6-0.7-0.6-2.6-1.1-2.6-0.1-0.10.4-0.5-0.10.10.3-0.8-0.9-1.20.1
Na content in liver2.32.56.82.12.2-2.22.2-1.61.61.61.61.42.6-1.12.60.70.7-0.62.50.60.4-0.50.70.50.8-1.7
Rb content in liver0.10.10.6-0.4-0.40.5-0.50.2-0.3-0.3-0.4-0.2-0.70.3-0.7-0.1-0.10.2-0.5-0.1-0.10.1-0.00.0-0.10.4
Se content in liver1.51.88.11.61.5-2.22.2-0.50.50.50.50.3-1.4-2.8-1.30.30.30.52.40.10.20.6-0.8-1.2-0.4-2.2
Sr content in liver0.60.51.5-0.2-0.3-0.10.10.7-0.6-0.6-0.6-0.8-0.9-0.4-0.9-0.7-0.70.80.4-0.7-0.70.9-1.1-1.20.1-0.9
Zn content in liver0.30.41.70.70.6-1.01.0-0.10.10.10.10.0-0.4-1.3-0.50.00.00.41.2-0.1-0.00.3-0.5-0.7-0.1-1.1
Bone: minimum diameter0.40.83.41.21.2-1.31.4-0.80.70.70.70.61.0-0.91.00.30.30.11.90.20.1-0.00.2-0.00.6-1.2
Time in familiar zone, hab. session 10.50.51.40.00.10.3-0.3-0.60.60.60.60.71.10.81.10.60.6-0.9-0.70.60.6-0.91.11.2-0.21.0
Time in novel zone, hab. session 13.94.46.4-2.0-2.01.6-1.62.4-2.5-2.5-2.5-2.5-1.61.3-1.6-2.4-2.42.5-0.5-2.4-2.32.5-2.5-2.41.5-0.9
Total zone transitions, hab. session 10.20.31.20.30.3-0.60.60.2-0.0-0.0-0.0-0.3-0.1-0.4-0.1-0.4-0.40.60.9-0.4-0.40.6-0.6-0.70.5-1.1
Total locomotion distance, hab. session 10.50.82.21.31.3-1.51.5-0.80.90.90.90.60.1-1.30.20.50.5-0.21.40.40.4-0.10.1-0.1-0.1-1.2
Locomotion velocity, hab. session 11.62.25.82.22.2-2.42.4-1.51.61.61.61.30.5-2.20.61.11.1-0.72.21.00.9-0.60.50.2-0.4-1.6
Time in familiar zone, hab. session 21.71.93.8-1.7-1.61.7-1.71.5-1.5-1.5-1.5-1.5-0.11.9-0.1-1.6-1.61.1-1.2-1.5-1.51.2-1.1-0.91.10.2
Time in novel zone, hab. session 20.20.31.20.70.6-0.80.8-0.40.30.30.30.3-0.5-1.1-0.50.40.4-0.00.80.40.4-0.10.0-0.1-0.3-0.5
Total zone transitions, hab. session 20.81.15.00.91.0-1.31.3-0.10.20.20.2-0.10.9-0.50.9-0.6-0.60.92.2-0.7-0.81.1-0.8-1.01.4-2.2
Total locomotion distance, hab. session 20.40.62.70.91.0-1.21.2-0.30.40.40.40.10.2-0.70.3-0.2-0.20.51.7-0.3-0.30.7-0.5-0.70.7-1.6
Locomotion velocity, hab. session 20.70.94.21.11.1-1.51.5-0.30.40.40.40.10.4-0.80.5-0.3-0.30.72.0-0.4-0.50.8-0.6-0.81.0-2.0
Novel to familiar place preference ratio0.70.91.81.01.0-1.01.0-1.10.90.90.91.1-0.2-1.4-0.21.11.1-1.00.51.11.1-0.90.80.7-1.00.1
Novelty place preference0.70.91.51.11.0-1.01.0-1.21.01.01.01.20.1-1.20.11.11.1-1.00.51.11.1-1.00.90.8-0.90.1
Time in novel zone, NPP test0.50.60.90.90.8-0.80.8-0.90.80.80.80.90.2-0.90.20.90.9-0.80.50.80.8-0.70.70.6-0.60.0
Total zone transitions, NPP test0.50.82.91.31.3-1.51.5-0.80.80.80.80.6-0.4-1.7-0.30.60.6-0.11.50.50.5-0.00.1-0.1-0.2-1.1
Total locomotion distance, NPP test1.62.28.21.91.7-2.12.0-1.41.41.41.41.3-1.4-2.9-1.31.51.5-0.81.41.41.5-0.80.60.3-1.5-0.7
Locomotion velocity, NPP test1.72.48.01.91.8-2.12.1-1.51.61.61.61.5-1.2-2.8-1.11.71.6-1.01.31.61.6-1.00.80.5-1.5-0.6
Intraocular pressure0.20.30.90.30.2-0.20.2-0.40.50.50.50.4-0.7-0.6-0.70.70.7-0.5-0.30.70.8-0.50.50.5-0.90.5
Delta distance traveled before/after self-admin3.23.510.0-2.5-2.42.7-2.62.0-2.0-2.0-2.0-1.80.23.20.3-1.9-1.91.3-2.0-1.8-1.81.3-1.0-0.71.70.9
Delta ambulatory time before/after self-admin1.42.58.2-2.0-1.82.1-2.01.6-1.6-1.6-1.6-1.50.32.90.4-1.7-1.61.3-1.4-1.6-1.61.3-0.9-0.61.70.5
Parametrial fat weight0.71.64.40.60.5-0.30.2-1.11.11.11.11.2-0.7-0.9-0.71.61.6-1.8-0.81.71.7-1.81.41.5-2.11.5
Pavlov. Cond. lever latency2.73.45.7-1.7-1.81.3-1.32.1-2.1-2.1-2.1-2.2-2.40.7-2.3-1.9-1.92.2-0.5-1.8-1.72.1-2.2-2.20.8-0.6
Pavlov. Cond. magazine entry latency0.60.71.50.50.5-0.20.2-0.90.90.90.90.91.1-0.11.00.90.9-1.2-0.21.00.9-1.21.21.2-0.60.8
Pavlov. Cond. change in total contacts1.61.77.11.31.4-1.11.1-1.41.41.41.41.42.7-0.12.60.90.9-1.21.00.90.7-1.11.31.30.3-0.2
Pavlov. Cond. index score2.63.37.41.61.7-1.21.2-2.02.12.12.12.12.7-0.52.61.71.7-2.10.51.71.6-2.02.22.2-0.50.6
Pavlov. Cond. latency score3.34.28.41.81.9-1.31.3-2.32.32.32.32.42.9-0.52.82.02.0-2.50.42.01.9-2.42.52.6-0.80.8
Pavlov. Cond. lever contacts3.44.16.41.81.9-1.41.4-2.32.32.32.32.42.5-0.72.52.12.1-2.50.42.12.0-2.42.52.5-0.90.8
Pavlov. Cond. magazine entry number0.40.52.7-0.5-0.50.3-0.30.7-0.7-0.7-0.7-0.7-1.6-0.2-1.6-0.5-0.50.7-0.2-0.5-0.40.7-0.9-0.9-0.2-0.2
Pavlov. Cond. intertrial magazine entries1.72.03.01.71.7-1.61.6-1.71.71.71.71.61.7-1.01.71.31.3-1.31.21.31.2-1.21.41.3-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.2.32.87.41.51.6-1.11.1-1.91.91.91.91.92.7-0.32.61.51.5-1.90.51.51.4-1.82.02.0-0.30.5
Pavlov. Cond. response bias0.81.03.20.80.8-0.50.5-1.11.11.11.11.11.8-0.01.70.90.9-1.20.20.90.8-1.21.31.3-0.20.4
Pavlov. Cond. lever latency1.82.56.8-2.0-2.12.0-2.11.7-1.6-1.6-1.6-1.6-2.61.0-2.6-0.9-0.91.0-2.1-0.8-0.70.7-1.0-0.8-0.51.3
Pavlov. Cond. magazine entry latency1.21.73.11.71.8-1.71.7-1.51.61.61.61.41.5-1.11.51.11.1-1.01.41.00.9-0.80.90.8-0.1-0.8
Pavlov. Cond. change in total contacts0.40.93.50.70.9-1.01.0-0.20.10.10.1-0.01.6-0.11.6-0.6-0.60.71.9-0.7-0.80.8-0.6-0.71.5-1.8
Pavlov. Cond. index score1.22.05.81.81.9-1.91.9-1.41.41.41.41.22.4-0.82.40.60.6-0.62.10.50.3-0.30.60.40.8-1.5
Pavlov. Cond. latency score1.42.35.92.02.1-2.12.1-1.61.61.61.61.42.4-1.02.40.80.8-0.82.20.70.5-0.50.70.60.6-1.5
Pavlov. Cond. lever contacts1.72.55.92.12.2-2.12.1-1.81.61.61.61.62.4-1.22.41.01.0-1.02.10.90.7-0.70.90.80.4-1.3
Pavlov. Cond. magazine entry number0.91.22.5-1.4-1.41.3-1.31.3-1.3-1.3-1.3-1.2-1.60.7-1.6-0.9-0.90.9-1.1-0.8-0.70.8-0.9-0.8-0.00.5
Pavlov. Cond. intertrial magazine entries1.53.38.90.90.7-0.60.5-1.51.41.41.41.6-1.5-1.8-1.62.32.3-2.2-1.02.42.5-2.32.01.9-3.02.0
Pavlov. Cond. lever-magazine prob. diff.1.11.75.81.61.7-1.71.7-1.31.31.31.31.12.4-0.72.40.50.5-0.52.00.40.3-0.30.60.50.9-1.4
Pavlov. Cond. response bias1.72.35.32.02.1-2.12.1-1.61.61.61.61.42.3-1.12.30.80.8-0.82.20.70.6-0.50.80.60.5-1.5
Time in closed arm before self-admin0.10.31.1-0.5-0.40.6-0.60.3-0.1-0.1-0.1-0.01.01.01.0-0.4-0.40.1-0.2-0.3-0.40.10.20.40.80.3
Time in closed arm after self-admin0.10.10.30.10.1-0.00.0-0.30.30.30.30.50.20.10.20.30.3-0.4-0.10.30.3-0.30.50.5-0.10.4
Time in open arm before self-admin0.20.20.7-0.2-0.20.00.00.3-0.6-0.6-0.6-0.5-0.50.1-0.6-0.5-0.50.6-0.1-0.5-0.50.6-0.7-0.80.2-0.6
Time in open arm after self-admin0.10.10.3-0.2-0.20.1-0.10.3-0.4-0.4-0.4-0.5-0.10.1-0.1-0.4-0.40.4-0.1-0.4-0.40.3-0.5-0.50.0-0.3
Bone: periosteal estimation0.10.21.10.60.6-0.70.7-0.40.30.30.30.30.4-0.40.40.10.10.21.00.0-0.00.1-0.0-0.10.4-0.8
Bone: periosteal perimeter0.00.10.50.30.3-0.40.4-0.10.00.00.00.00.3-0.20.3-0.1-0.10.30.7-0.2-0.20.2-0.2-0.30.4-0.6
Bone: post-yield work0.10.21.2-0.6-0.60.7-0.70.2-0.2-0.2-0.2-0.1-0.30.5-0.30.20.2-0.3-1.10.20.2-0.40.30.4-0.51.0
Progressive ratio test 1 active lever presses0.20.31.1-0.8-0.81.0-1.00.3-0.4-0.4-0.4-0.3-0.01.00.0-0.2-0.2-0.2-1.0-0.2-0.2-0.10.10.2-0.10.9
Progressive ratio test 1 breakpoint0.20.41.3-0.9-0.91.0-1.10.4-0.5-0.5-0.5-0.40.01.20.1-0.4-0.4-0.1-1.0-0.3-0.3-0.0-0.00.1-0.00.8
Progressive ratio test 1 inactive lever presses0.30.83.3-0.3-0.40.7-0.6-0.30.20.20.20.5-0.50.1-0.40.90.9-1.3-1.51.01.0-1.31.11.2-1.31.8
Progressive ratio test 2 active lever presses0.20.31.4-0.6-0.60.8-0.90.2-0.2-0.2-0.2-0.0-0.20.6-0.10.10.2-0.5-1.10.20.2-0.50.40.6-0.41.2
Progressive ratio test 2 breakpoint0.20.21.1-0.4-0.40.7-0.70.0-0.0-0.0-0.10.1-0.10.5-0.00.20.2-0.5-0.90.30.3-0.50.50.6-0.31.0
Progressive ratio test 2 inactive lever presses0.20.81.80.50.4-0.20.1-1.00.80.80.81.00.3-0.10.41.11.1-1.2-0.41.11.1-1.21.31.3-0.81.1
Incentive Sensitization - Responses0.10.20.60.00.00.1-0.1-0.30.30.30.20.30.0-0.10.10.50.5-0.7-0.50.60.6-0.70.60.7-0.50.8
Incentive Sensitization - Breakpoint0.10.30.70.20.2-0.00.0-0.40.50.50.40.50.1-0.30.10.70.7-0.9-0.40.70.7-0.80.80.8-0.70.8
Sum of active levers in priming session hrs 5-62.32.23.5-1.8-1.91.7-1.61.8-1.8-1.8-1.8-1.8-1.81.1-1.8-1.3-1.31.2-1.4-1.2-1.11.1-1.4-1.4-0.00.4
Progressive ratio0.51.52.4-1.5-1.51.4-1.41.4-1.5-1.5-1.5-1.5-1.40.8-1.5-1.2-1.21.0-1.2-1.1-1.01.0-1.2-1.10.10.3
Food seeking constrained by brief footshock9.511.917.5-4.2-4.23.8-3.94.1-4.1-4.1-4.1-4.1-1.93.2-2.0-3.8-3.83.2-2.4-3.7-3.53.3-3.6-3.31.80.1
Seeking ratio, punishment vs. effort0.30.61.5-0.8-0.70.8-0.80.7-0.7-0.7-0.7-0.70.71.20.8-0.9-0.90.7-0.1-0.9-0.90.7-0.6-0.51.1-0.1
Retroperitoneal fat weight0.41.64.30.40.40.1-0.2-1.11.21.21.11.30.70.20.71.41.4-1.8-1.01.51.5-1.81.92.1-1.21.8
Reaction time number correct0.93.25.2-2.2-2.22.0-2.02.1-2.3-2.3-2.3-2.1-1.21.6-1.3-1.9-1.91.8-1.3-1.8-1.81.7-1.7-1.61.00.2
Reaction time mean minus median0.21.24.31.51.6-1.71.7-0.91.01.01.10.71.4-1.01.50.20.2-0.12.10.10.00.1-0.0-0.20.7-1.8
Reaction time mean minus median AUC0.10.61.90.91.0-1.01.0-0.70.80.80.80.51.3-0.41.40.20.2-0.31.20.20.1-0.10.20.20.5-0.9
Reaction time num false alarms0.20.31.10.60.7-0.60.6-0.60.50.50.50.61.0-0.21.00.40.4-0.50.70.30.3-0.40.50.40.1-0.3
Reaction time num false alarms AUC0.10.30.80.60.6-0.50.5-0.70.50.50.50.70.9-0.10.90.50.5-0.60.40.50.5-0.60.70.6-0.10.0
Reaction time trials correct on left0.93.25.2-2.2-2.22.0-2.02.1-2.3-2.3-2.3-2.1-1.21.6-1.3-1.9-1.91.8-1.3-1.8-1.81.7-1.7-1.61.00.2
Reaction time trials on left0.93.15.0-2.1-2.12.0-1.92.0-2.2-2.2-2.2-2.0-1.31.5-1.3-1.8-1.81.7-1.3-1.7-1.71.6-1.7-1.60.80.2
Reaction time mean0.51.13.31.31.4-1.51.5-0.91.01.01.00.81.6-0.81.70.30.3-0.21.80.20.1-0.00.20.10.7-1.4
Reaction time mean AUC0.51.13.91.31.4-1.51.5-0.80.80.80.90.61.7-0.71.70.10.10.02.0-0.0-0.10.2-0.1-0.20.9-1.7
Median of all reaction times0.40.62.01.01.0-1.11.0-0.70.70.70.80.61.4-0.51.40.20.2-0.21.40.10.1-0.00.20.10.6-1.0
Reaction time omissions0.40.71.80.70.6-0.80.7-0.70.70.70.70.8-0.9-1.4-0.81.01.0-0.90.11.01.0-0.80.50.4-1.30.2
Reaction time false alarm rate1.11.52.11.31.3-1.11.1-1.41.41.41.41.41.2-0.71.21.31.3-1.40.71.21.2-1.31.41.3-0.60.2
Reaction time premature initiation rate0.71.04.0-1.3-1.21.4-1.40.9-1.0-1.0-1.0-0.70.92.00.9-1.0-1.00.6-1.0-0.9-1.00.5-0.3-0.11.10.5
Reaction time premature initiations1.13.47.5-2.4-2.32.5-2.42.0-2.2-2.2-2.2-1.80.22.70.1-1.9-1.91.5-1.7-1.8-1.81.3-1.2-1.01.50.7
Std. dev. reaction times0.20.72.81.11.1-1.31.2-0.60.80.80.80.41.1-0.71.20.00.00.11.7-0.1-0.10.3-0.2-0.30.8-1.5
Reaction time trials completed0.93.15.0-2.1-2.12.0-1.92.0-2.2-2.2-2.2-2.0-1.31.5-1.3-1.8-1.81.7-1.3-1.7-1.71.6-1.7-1.60.80.2
Reaction time trials AUC0.93.15.1-2.1-2.11.9-1.92.1-2.2-2.2-2.2-2.0-1.31.4-1.4-1.8-1.81.7-1.3-1.7-1.71.6-1.7-1.60.80.2
Run reversals in cocaine runway, females0.40.53.0-0.0-0.2-0.10.00.20.00.00.0-0.1-1.7-1.1-1.70.40.4-0.3-0.50.40.6-0.3-0.2-0.3-1.40.4
Run reversals in cocaine runway, males0.50.52.10.30.4-0.50.6-0.00.00.00.0-0.21.00.11.0-0.6-0.60.81.1-0.7-0.80.9-0.5-0.61.4-1.4
Latency to leave start box in cocaine runway0.70.92.2-0.5-0.50.2-0.20.8-1.1-1.1-1.1-1.2-0.40.0-0.4-1.1-1.21.30.5-1.2-1.21.3-1.4-1.50.9-1.1
Latency to leave start box in cocaine runway, F0.70.91.8-0.5-0.40.2-0.20.8-0.9-0.9-0.9-1.10.20.40.2-1.2-1.21.30.6-1.2-1.31.3-1.2-1.31.3-1.1
Latency to leave start box in cocaine runway, M0.50.41.3-0.3-0.3-0.00.00.5-0.8-0.8-0.8-0.8-0.9-0.5-0.9-0.6-0.60.60.3-0.6-0.60.7-1.1-1.2-0.1-0.7
Std. dev. time between licks in bursts2.44.59.22.82.7-2.82.8-2.42.32.32.32.30.4-3.00.42.32.2-1.72.12.12.1-1.81.61.3-1.4-0.7
Total sessions with >9 infusions0.20.30.60.50.6-0.40.4-0.60.60.60.60.60.7-0.10.80.50.5-0.70.30.50.5-0.60.60.6-0.10.1
Short access day 1 total inactive lever presses0.91.83.21.81.8-1.81.8-1.51.61.61.61.41.2-1.41.21.31.3-1.11.51.21.1-1.01.10.9-0.4-0.6
Short access day 10 total inactive lever presses0.00.10.3-0.0-0.00.1-0.1-0.10.20.20.20.20.0-0.1-0.00.40.4-0.3-0.50.40.4-0.30.40.4-0.40.5
Short access day 1 total infusions0.10.20.60.30.3-0.20.2-0.50.40.40.40.50.70.00.80.40.4-0.60.10.40.3-0.50.50.5-0.00.2
Short access day 10 total infusions0.30.41.90.90.9-1.01.0-0.50.50.50.50.40.9-0.30.90.10.1-0.01.4-0.0-0.00.1-0.1-0.20.6-1.1
Short access total infusions0.10.10.30.40.5-0.40.4-0.50.40.40.40.50.5-0.10.50.30.3-0.40.40.30.3-0.30.30.30.1-0.1
Short access day 1 locomotion0.71.14.01.31.4-1.41.5-0.90.70.70.70.72.0-0.52.00.20.1-0.21.90.0-0.10.00.1-0.10.9-1.5
Short access day 10 total locomotion0.20.81.91.11.1-1.01.0-1.11.01.01.01.01.4-0.51.40.80.7-1.00.90.70.7-0.80.80.7-0.2-0.3
Short access total locomotion0.91.43.81.51.5-1.51.5-1.31.21.21.21.22.0-0.62.00.80.8-1.01.50.70.6-0.70.80.70.2-0.8
One hour access (0.3 mA shock)0.30.41.00.70.7-0.80.7-0.70.60.60.50.7-0.3-1.0-0.30.70.7-0.60.30.70.7-0.60.40.3-0.9-0.0
Compulsive drug intake1.52.23.31.71.7-1.51.6-1.71.81.81.71.80.6-1.40.61.71.7-1.30.81.71.6-1.51.71.5-0.90.2
One hour access (shock baseline)0.10.30.7-0.5-0.50.3-0.30.5-0.7-0.7-0.7-0.6-0.40.1-0.4-0.6-0.60.4-0.0-0.6-0.50.5-0.8-0.80.0-0.3
Social response proportion2.12.65.9-2.3-2.32.4-2.41.7-1.8-1.8-1.9-1.6-1.01.9-1.0-1.4-1.41.0-2.1-1.3-1.21.0-1.0-0.70.51.2
Social responses0.30.41.6-0.6-0.70.8-0.80.2-0.4-0.4-0.4-0.1-1.20.1-1.10.20.2-0.4-1.30.30.4-0.40.20.3-0.91.2
Social time0.71.01.81.31.3-1.31.3-1.21.11.11.21.20.2-1.30.21.11.1-0.81.01.01.0-0.70.80.7-0.5-0.3
Soleus weight4.011.819.8-2.8-2.82.0-2.03.9-3.8-3.8-3.9-4.1-2.71.6-2.6-4.0-4.04.40.2-4.0-3.94.3-4.4-4.42.7-2.3
Bone: stiffness1.01.99.51.11.3-0.90.9-1.41.41.41.41.33.10.33.00.90.9-1.10.90.80.7-1.11.41.50.7-0.0
Tibialis anterior weight3.110.527.8-1.7-1.41.1-0.92.8-2.7-2.7-2.8-3.22.13.02.0-4.1-4.14.12.0-4.2-4.54.2-3.5-3.55.3-3.6
Time to tail flick, vehicle, before self-admin0.70.81.50.40.4-0.10.2-0.70.90.90.90.9-0.6-0.5-0.51.21.2-1.0-0.61.21.2-1.21.21.2-1.21.2
Time to tail flick, vehicle, after self-admin2.24.58.0-2.8-2.72.8-2.82.4-2.3-2.3-2.3-2.3-1.02.8-1.0-2.1-2.12.0-1.9-2.0-2.01.8-1.6-1.31.30.8
Time to tail flick, test, before self-admin1.71.92.91.41.4-1.31.2-1.61.61.61.61.6-0.0-1.7-0.01.71.7-1.50.41.71.7-1.41.41.3-1.40.5
Time to tail flick, test, after self-admin1.11.13.8-0.1-0.20.4-0.5-0.40.50.50.50.8-0.8-0.2-0.71.21.2-1.4-1.41.31.4-1.51.31.4-1.72.0
Delta time to tail flick, vehicle, before/after SA2.12.33.8-1.9-1.91.9-1.91.8-1.8-1.8-1.8-1.7-0.71.8-0.7-1.6-1.61.3-1.2-1.5-1.41.3-1.3-1.20.90.4
Delta time to tail flick, test, before/after SA0.91.14.0-1.4-1.51.7-1.71.0-0.9-0.9-0.9-0.6-0.91.4-0.9-0.2-0.20.0-2.0-0.1-0.1-0.20.10.3-0.51.7
Tibia length7.420.630.85.15.1-4.64.5-5.55.55.55.65.43.7-3.73.74.94.9-4.82.54.84.6-4.54.84.5-2.40.3
Ambulatory time before self-admin0.20.62.00.10.2-0.50.50.5-0.4-0.4-0.4-0.70.1-0.5-0.0-0.8-0.81.01.1-0.8-0.80.9-1.1-1.20.7-1.4
Ambulatory time after self-admin2.33.76.6-1.4-1.31.1-1.02.0-1.9-1.9-1.9-2.20.41.90.4-2.5-2.52.50.4-2.5-2.62.4-2.2-2.22.5-1.6
Bone: tissue strength0.60.71.11.01.0-1.01.0-1.01.01.00.90.90.6-0.70.70.80.8-0.80.70.80.7-0.70.80.7-0.3-0.2
Total heroin consumption1.01.22.7-0.6-0.60.3-0.21.1-1.1-1.1-1.1-1.3-0.40.4-0.5-1.3-1.31.50.2-1.4-1.31.6-1.6-1.71.0-1.2
Bone: trabecular number0.50.92.80.80.7-0.80.8-0.80.80.80.80.8-1.1-1.7-1.11.11.1-0.90.21.11.2-0.90.60.5-1.60.4
Bone: trabecular spacing0.60.92.5-0.7-0.60.6-0.60.8-0.8-0.8-0.8-0.90.81.30.8-1.2-1.21.10.2-1.2-1.21.1-0.8-0.71.6-0.6
Bone: trabecular thickness0.50.72.20.90.9-1.00.9-0.80.90.90.90.8-0.6-1.5-0.51.01.0-0.80.51.01.0-0.70.60.5-1.10.0
Bone: trabecular tissue density0.50.92.5-0.4-0.30.1-0.10.8-0.8-0.8-0.8-1.00.40.60.3-1.2-1.21.40.8-1.2-1.31.3-1.1-1.11.6-1.2
Water consumed over 24 hours0.20.32.10.10.2-0.10.1-0.0-0.1-0.1-0.1-0.11.40.71.4-0.4-0.40.20.6-0.4-0.50.3-0.1-0.11.0-0.6
Number of responses in last shaping day0.40.51.0-0.6-0.60.5-0.40.8-0.9-0.9-0.8-0.80.30.40.3-0.9-0.90.8-0.1-0.9-0.90.8-0.8-0.91.0-0.5