Hub : Genes

Fn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Fn1 0.46 0.16 7.3e-12 0.32 0.41 0.36 0.42 2.3e-08 7.1e-11 1.9e-09 3.6e-11
2 Adipose mRNA stability Fn1 0.04 0.03 2.2e-04 0.01 0.02 0.01 0.02 1.4e-02 3.1e-03 1.4e-02 6.0e-03
3 Adipose isoform ratio XM_006245152.5 0.03 0.02 2.7e-03 0.01 0.02 0.02 0.01 2.5e-02 6.6e-03 5.5e-03 3.0e-02
4 PL intron excision ratio chr9_80674521_80675826 0.02 0.02 1.2e-03 0.04 0.02 0.01 0.03 4.1e-05 4.4e-03 4.0e-02 1.4e-04
5 LHb gene expression Fn1 0.43 0.16 4.6e-08 0.23 0.22 0.26 0.25 3.0e-06 7.2e-06 6.4e-07 1.1e-06
6 Adipose intron excision ratio chr9_80662594_80663712 0.04 0.03 3.9e-05 0.03 0.03 0.02 0.02 6.7e-04 2.7e-04 1.4e-03 1.7e-03
7 pVTA gene expression Fn1 0.4 0.11 0.0e+00 0.44 0.49 0.48 0.48 5.5e-39 1.1e-44 9.4e-43 2.2e-43
8 IL gene expression Fn1 0.29 0.16 4.7e-05 0.11 0.15 0.19 0.16 1.7e-03 2.1e-04 2.7e-05 1.2e-04
9 RMTg gene expression Fn1 0.18 0.11 2.6e-04 0.1 0.12 0.1 0.12 1.1e-03 4.9e-04 1.4e-03 5.2e-04
10 Adipose intron excision ratio chr9_80673142_80675826 0.02 0.02 7.1e-03 0.01 0.01 0 0.01 3.6e-02 3.6e-02 1.5e-01 3.1e-02
11 PL gene expression Fn1 0.27 0.1 0.0e+00 0.38 0.39 0.4 0.4 7.3e-44 1.0e-45 7.6e-46 3.8e-46
12 Adipose intron excision ratio chr9_80662594_80664810 0.13 0.08 3.6e-13 0.1 0.09 0.1 0.09 2.0e-11 2.4e-10 1.1e-10 1.2e-10
13 Adipose intron excision ratio chr9_80663981_80664810 0.15 0.09 1.5e-11 0.08 0.08 0.07 0.08 1.8e-09 3.2e-09 1.5e-08 2.0e-09
14 NAcc isoform ratio XM_006245156.5 0.03 0.03 8.0e-03 0.02 0.01 0.01 0.01 1.4e-03 7.2e-03 2.1e-03 3.9e-03
15 Liver intron excision ratio chr9_80657469_80658083 0.06 0.04 2.8e-05 0.03 0.03 0.02 0.02 1.8e-04 5.9e-04 2.9e-03 1.5e-03
16 Brain gene expression Fn1 0.58 0.01 0.0e+00 0.55 0.57 0.56 0.56 1.2e-60 6.9e-64 6.5e-63 8.3e-63
17 Adipose isoform ratio XM_006245156.5 0.38 0.27 2.8e-05 0.04 0.02 0.02 0.04 1.9e-05 4.3e-03 1.5e-03 2.7e-05
18 IC gene expression Fn1 0.53 0.1 0.0e+00 0.41 0.5 0.47 0.51 1.4e-18 5.8e-24 8.9e-22 2.3e-24
19 Adipose intron excision ratio chr9_80674521_80675826 0.03 0.02 1.1e-03 0.02 0.01 0.01 0.01 5.3e-03 2.4e-02 6.5e-02 3.1e-02
20 BLA gene expression Fn1 0.3 0.13 1.7e-15 0.24 0.26 0.26 0.26 4.2e-13 4.3e-14 6.6e-14 4.5e-14
21 NAcc gene expression Fn1 0.48 0 0.0e+00 0.32 0.34 0.33 0.34 3.0e-50 2.3e-53 2.7e-52 1.1e-52
22 BLA mRNA stability Fn1 0.24 0.15 8.4e-03 -0 0.02 0.03 0.01 8.5e-01 4.3e-02 1.1e-02 5.1e-02
23 Liver isoform ratio XM_006245156.5 0.06 0.04 5.6e-05 0.02 0.03 0.02 0.02 8.9e-04 4.1e-04 2.4e-03 2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.40.81.71.01.0-1.00.80.9-0.90.80.50.81.20.81.3-1.30.91.10.70.90.6-0.80.60.50.20.6
Area under the delay curve0.91.11.61.21.3-1.21.11.1-1.21.10.91.11.21.21.0-1.00.80.91.00.81.1-1.31.00.9-0.30.9
BMI with tail0.82.74.71.61.8-1.81.91.9-1.81.92.21.81.31.81.0-1.01.30.91.81.21.8-1.61.81.80.71.7
BMI without tail2.16.311.6-3.2-3.42.7-2.7-2.73.0-3.0-2.4-2.7-2.5-2.7-2.22.2-1.0-2.0-2.7-1.1-2.72.4-2.6-2.6-0.8-2.2
Body weight0.31.22.9-1.7-1.21.6-1.3-1.41.1-0.9-0.9-0.9-1.0-0.8-1.21.2-1.2-1.2-0.8-1.3-0.60.7-0.6-0.6-0.5-0.7
Weight adjusted by age1.11.63.31.41.5-1.71.81.5-1.41.41.21.31.21.31.1-1.10.91.01.20.91.2-1.31.21.20.81.1
Bone surface0.71.22.41.31.4-1.31.11.1-1.21.00.71.01.41.01.5-1.51.01.50.81.00.8-1.10.70.60.70.7
Bone volume0.40.81.71.01.1-1.00.70.8-1.00.90.40.91.20.91.3-1.30.81.20.80.80.8-0.90.70.60.20.7
Breakpoint value in progressive ratio session0.20.20.60.60.8-0.40.80.4-0.50.70.40.50.00.5-0.10.1-0.2-0.10.5-0.20.6-0.10.50.50.60.2
Number of licking bursts1.01.66.70.0-0.0-1.00.30.8-0.60.20.50.71.50.62.0-2.02.62.00.52.60.3-0.70.40.2-2.21.1
Context. condit. distance diff. score0.10.10.20.20.2-0.10.00.1-0.30.4-0.00.30.30.40.2-0.20.0-0.10.40.00.5-0.30.50.50.30.4
Locomotion velocity, session 10.10.10.2-0.1-0.50.2-0.2-0.20.3-0.2-0.1-0.2-0.3-0.1-0.30.3-0.3-0.5-0.1-0.3-0.20.1-0.1-0.0-0.1-0.1
Locomotion distance, session 10.20.20.6-0.4-0.70.3-0.5-0.40.5-0.7-0.5-0.5-0.0-0.30.2-0.20.30.2-0.60.3-0.50.2-0.6-0.6-0.5-0.4
Locomotion velocity, session 20.10.10.5-0.3-0.40.2-0.3-0.20.2-0.2-0.2-0.10.40.20.6-0.60.20.4-0.10.20.1-0.2-0.0-0.0-0.70.1
Locomotion distance, session 20.30.40.90.90.6-0.80.90.8-0.50.50.70.40.70.70.6-0.60.40.70.30.40.5-0.70.40.30.40.3
Locomotion velocity, session 30.20.20.6-0.5-0.60.6-0.8-0.70.4-0.4-0.6-0.3-0.1-0.40.1-0.1-0.10.2-0.2-0.1-0.40.3-0.2-0.2-0.8-0.1
Locomotion distance, session 30.30.41.2-1.1-0.80.8-1.0-0.90.6-0.6-0.7-0.4-0.4-0.6-0.20.2-0.20.0-0.3-0.2-0.60.5-0.4-0.3-1.0-0.2
Stereotopy head waving bouts, day 30.30.41.71.10.6-0.90.60.8-0.60.30.60.40.2-0.20.4-0.41.30.50.11.3-0.30.1-0.1-0.2-0.50.2
Stereotopy head waving duration, day 30.70.82.41.30.9-1.20.81.0-0.90.60.60.70.90.41.1-1.11.61.10.51.60.3-0.50.30.2-0.40.6
Locomotion velocity, session 70.10.11.20.4-0.10.00.30.10.2-0.10.2-0.2-0.4-0.3-0.40.4-0.5-0.3-0.2-0.5-0.20.2-0.2-0.11.1-0.3
Locomotion distance, session 70.30.41.80.40.5-0.00.50.2-0.30.60.40.3-0.30.4-0.80.8-1.1-0.70.6-1.10.6-0.30.70.81.30.2
Stereotopy head waving bouts, day 70.20.20.5-0.5-0.60.2-0.4-0.40.5-0.6-0.5-0.5-0.1-0.70.3-0.30.30.2-0.60.3-0.70.4-0.7-0.7-0.5-0.4
Stereotopy head waving duration, day 70.30.41.6-0.1-0.3-0.3-0.10.1-0.0-0.2-0.10.10.6-0.11.0-1.01.21.0-0.01.2-0.1-0.2-0.1-0.2-1.30.3
Locomotion velocity, session 82.73.24.32.11.9-2.12.02.1-1.92.01.91.91.82.01.8-1.81.41.41.91.41.7-1.71.81.90.31.8
Locomotion distance, session 80.50.71.20.90.8-0.80.70.8-0.90.90.50.91.01.10.7-0.70.70.50.90.71.1-1.10.90.90.30.8
Degree of sensitization distance0.70.72.11.11.1-0.71.00.8-0.81.00.90.70.31.0-0.10.1-0.5-0.20.9-0.51.0-0.71.01.01.40.5
Degree of sensitization stereotypy0.20.31.0-1.0-0.80.5-0.7-0.60.5-0.6-0.7-0.40.2-0.30.4-0.40.10.3-0.30.1-0.30.1-0.4-0.4-0.8-0.2
Conditioned locomotion0.91.01.5-1.0-1.11.0-0.9-1.01.1-1.2-0.7-1.1-1.1-1.2-1.21.2-0.6-1.2-1.2-0.7-1.10.9-1.1-1.1-0.4-1.1
Cocaine response after cond. corrected4.85.710.2-3.2-3.02.9-3.0-2.92.7-2.7-2.8-2.5-2.2-2.5-1.81.8-1.5-1.9-2.3-1.5-2.32.5-2.3-2.3-1.3-2.0
Cocaine response after cond. not corrected2.83.36.1-2.5-2.22.2-2.2-2.22.0-1.9-2.0-1.8-1.8-1.9-1.41.4-1.5-1.7-1.6-1.5-1.82.1-1.6-1.5-0.7-1.5
Cocaine response before conditioning3.03.65.52.22.3-2.22.32.2-2.12.22.22.01.81.81.8-1.81.11.72.01.11.7-1.71.92.01.11.7
Saline control response0.50.71.70.1-0.10.2-0.0-0.30.6-0.7-0.2-0.9-0.9-1.3-0.50.5-0.7-0.5-1.1-0.7-1.31.2-1.2-1.21.3-1.3
Bone: connectivity density0.30.51.50.80.9-0.90.70.7-0.70.50.40.50.90.51.2-1.20.71.20.30.70.2-0.50.20.10.50.2
Bone: cortical apparent density0.40.62.41.41.0-0.61.20.8-0.50.61.30.2-0.40.2-0.60.6-0.8-0.60.2-0.80.20.20.20.31.6-0.2
Bone: cortical area0.50.71.9-0.8-0.30.9-0.9-0.90.7-0.5-1.2-0.7-0.8-0.6-0.90.9-1.3-1.4-0.7-1.3-0.40.6-0.7-0.70.8-1.0
Bone: cortical porosity0.00.00.1-0.1-0.40.00.10.10.10.00.30.0-0.00.10.0-0.0-0.1-0.00.2-0.10.1-0.20.30.3-0.20.3
Bone: cortical porosity0.10.10.6-0.6-0.70.3-0.3-0.30.4-0.4-0.1-0.3-0.2-0.3-0.00.0-0.0-0.1-0.1-0.0-0.30.2-0.1-0.1-0.50.0
Bone: cortical thickness0.81.43.9-0.9-0.61.2-0.9-1.11.0-0.7-1.1-1.0-1.2-0.9-1.41.4-2.0-1.8-0.9-2.0-0.60.9-0.8-0.71.2-1.2
Bone: cortical thickness1.51.82.3-1.3-1.31.4-1.2-1.41.5-1.4-1.3-1.5-1.2-1.5-0.90.9-1.5-1.3-1.5-1.5-1.41.4-1.4-1.40.7-1.5
Bone: cortical tissue density0.50.62.51.61.1-0.81.30.9-0.60.71.40.4-0.30.3-0.50.5-0.6-0.50.3-0.60.30.10.40.41.5-0.0
Condit. Reinf. active minus inactive responses1.31.44.7-1.8-1.51.3-1.8-1.31.1-1.4-1.5-1.0-0.6-1.0-0.30.30.4-0.3-1.10.4-1.11.1-1.2-1.2-2.2-0.7
Condit. Reinf. active-inactive response ratio3.03.26.7-2.5-2.21.9-2.6-2.11.8-2.1-2.3-1.6-1.4-1.9-0.90.90.2-0.8-1.70.2-2.02.0-1.9-1.9-2.3-1.2
Condit. Reinf. active responses0.60.81.7-1.3-1.20.9-1.1-0.91.0-1.1-1.0-0.9-0.6-0.8-0.50.5-0.0-0.6-1.0-0.0-0.80.7-1.0-1.0-1.3-0.7
Condit. Reinf. inactive responses0.10.10.50.30.2-0.30.60.4-0.10.20.50.10.20.5-0.10.1-0.4-0.30.2-0.40.6-0.70.30.30.60.1
Incentive salience index mean0.70.83.0-1.5-1.21.1-1.5-1.10.8-1.0-1.2-0.7-0.5-0.6-0.30.30.2-0.3-0.80.2-0.60.8-0.8-0.8-1.7-0.4
Condit. Reinf. lever presses0.30.50.9-0.8-0.60.9-0.7-0.80.7-0.5-0.6-0.6-0.8-0.4-0.90.9-1.0-0.9-0.5-1.0-0.30.6-0.4-0.4-0.1-0.5
Condit. Reinf. active minus inactive responses0.00.00.00.1-0.10.0-0.0-0.00.1-0.0-0.0-0.0-0.1-0.1-0.00.0-0.0-0.00.0-0.0-0.20.1-0.00.00.10.0
Condit. Reinf. active-inactive response ratio0.10.10.4-0.4-0.60.4-0.4-0.30.3-0.3-0.2-0.2-0.1-0.10.1-0.1-0.10.1-0.0-0.1-0.20.10.00.1-0.60.1
Condit. Reinf. active responses0.50.62.91.31.1-0.91.21.0-0.80.90.90.70.40.50.4-0.4-0.10.50.7-0.10.5-0.50.60.71.70.4
Condit. Reinf. inactive responses3.24.28.83.03.0-2.62.82.5-2.32.32.21.91.81.71.7-1.71.01.81.81.01.6-1.61.61.62.41.2
Condit. Reinf. lever presses0.60.92.61.61.3-1.21.51.3-1.01.01.30.80.60.70.6-0.60.20.60.70.20.6-0.60.70.71.60.5
Condit. Reinf. lever reinforcers received0.20.32.50.90.7-0.60.80.6-0.50.50.60.30.20.20.2-0.2-0.20.30.4-0.20.2-0.20.30.41.60.1
Conditioned reinforcement - actives0.40.72.70.50.7-0.40.00.4-0.90.80.40.91.00.90.8-0.81.00.90.91.01.0-0.90.80.8-1.60.9
Conditioned reinforcement - inactives0.50.81.20.70.8-0.70.30.9-0.90.91.11.01.01.00.7-0.71.00.81.00.81.1-1.11.00.9-0.71.0
Conditioned locomotion4.86.27.82.42.3-2.21.62.2-2.72.52.22.72.82.62.5-2.52.72.42.72.82.6-2.62.62.5-2.12.8
Patch foraging indifference point 0 sec1.01.95.02.02.0-2.12.21.9-1.51.41.61.21.20.91.2-1.20.81.20.90.80.8-1.30.80.70.90.6
Patch foraging indifference point AUC1.42.13.71.51.4-1.21.21.4-1.51.61.41.61.51.71.2-1.21.01.11.70.91.9-1.61.81.70.11.6
Delay disc. indifference point, 0s delay1.21.33.91.71.6-1.52.01.4-1.21.31.31.10.71.20.5-0.50.10.41.00.11.0-1.01.01.11.40.7
Delay disc. indifference point, 16s delay0.10.10.40.30.3-0.70.50.5-0.30.30.20.30.40.40.5-0.50.30.40.30.30.3-0.50.30.20.20.3
Delay disc. indifference point, 2s delay4.14.65.82.42.4-2.21.82.1-2.42.42.22.42.32.41.9-1.91.71.82.31.72.2-2.42.32.3-0.62.2
Delay disc. indifference point, 24s delay1.11.23.50.10.2-0.70.00.5-0.70.40.00.91.40.81.7-1.71.91.70.81.90.7-1.00.70.6-1.51.1
Delay disc. indifference point, 4s delay2.02.13.91.92.0-1.61.71.5-1.71.81.61.61.31.61.0-1.00.50.91.60.61.5-1.61.61.60.61.3
Delay disc. indifference point, 8s delay0.00.00.10.30.4-0.20.40.1-0.20.1-0.20.00.30.20.4-0.4-0.10.3-0.0-0.10.1-0.3-0.1-0.10.2-0.2
Indifference point function ln k1.32.34.5-1.4-1.11.2-1.0-1.31.5-1.5-1.4-1.6-1.7-1.9-1.31.3-1.4-1.2-1.7-1.4-2.11.7-1.8-1.80.7-1.8
Indifference point function log k1.32.34.5-1.4-1.11.2-1.0-1.31.5-1.5-1.4-1.6-1.7-1.9-1.31.3-1.4-1.2-1.7-1.4-2.11.7-1.8-1.80.7-1.8
Patch foraging total patch changes 0 sec0.81.54.41.81.8-1.92.11.7-1.41.21.41.01.10.81.1-1.10.71.10.80.70.7-1.10.70.60.90.5
Patch foraging total patch changes 12 sec3.24.27.02.62.6-2.52.62.5-2.32.22.32.02.01.91.9-1.91.61.71.81.51.9-2.11.81.71.01.6
Patch foraging total patch changes 18 sec3.55.37.32.42.3-2.72.42.6-2.42.22.22.32.72.32.7-2.72.52.72.12.42.1-2.41.91.8-0.42.1
Patch foraging total patch changes 24 sec0.71.12.41.31.2-1.51.51.4-1.11.01.30.91.10.91.1-1.11.11.10.81.00.9-1.10.70.7-0.20.7
Patch foraging total patch changes 6 sec3.95.97.92.82.8-2.82.62.7-2.72.52.32.52.72.42.6-2.62.22.62.32.12.3-2.52.22.10.12.1
Patch foraging time to switch 0 sec0.81.62.71.11.1-1.20.81.2-1.31.21.01.31.51.51.4-1.41.61.31.21.61.5-1.31.21.1-0.61.3
Patch foraging water rate 0 sec0.61.32.1-1.5-1.41.1-0.8-1.11.4-1.3-1.0-1.3-1.2-1.3-1.01.0-1.2-0.9-1.2-1.2-1.41.1-1.1-1.00.4-1.1
Patch foraging water rate 12 sec0.20.41.1-0.4-0.40.4-0.6-0.50.5-0.6-0.7-0.6-0.5-0.9-0.30.30.2-0.2-0.70.2-1.00.8-0.8-0.9-0.5-0.6
Patch foraging water rate 18 sec0.60.92.3-1.0-0.80.6-0.7-0.80.9-1.1-1.1-1.1-0.7-1.3-0.40.40.0-0.2-1.2-0.0-1.51.1-1.4-1.4-0.1-1.1
Patch foraging water rate 24 sec0.10.20.50.30.2-0.30.10.2-0.30.2-0.10.30.50.20.7-0.70.70.70.20.70.0-0.20.10.1-0.50.3
Patch foraging water rate 6 sec0.91.32.3-1.0-1.00.8-0.7-0.91.1-1.2-1.0-1.3-1.2-1.4-1.11.1-0.8-1.0-1.4-0.8-1.51.4-1.4-1.40.2-1.4
Seeking ratio, delayed vs. immediate footshock0.60.71.10.91.0-1.01.10.8-1.00.90.50.90.90.80.8-0.80.80.70.80.80.8-0.90.80.70.40.8
Distance traveled before self-admin0.10.11.60.20.3-0.30.40.2-0.30.30.10.30.10.2-0.10.10.3-0.20.20.40.3-0.20.20.2-1.30.2
Distance traveled after self-admin0.30.42.51.01.0-0.81.60.6-0.60.70.50.40.20.5-0.10.1-0.0-0.30.4-0.10.6-0.40.40.4-0.10.1
Extensor digitorum longus weight0.10.42.30.10.2-0.5-0.00.3-0.2-0.20.00.00.4-0.50.9-0.91.50.7-0.31.5-0.60.3-0.5-0.6-1.1-0.1
Bone: elastic displacement0.20.21.11.10.4-0.70.90.7-0.30.20.70.20.10.00.1-0.10.20.10.00.20.1-0.20.00.00.7-0.0
Bone: elastic work0.70.92.81.71.0-1.41.41.3-0.90.81.20.70.90.60.9-0.91.00.80.51.00.6-0.90.50.40.40.5
Bone: endosteal estimation0.30.60.90.70.9-0.90.70.8-0.90.80.60.80.80.60.9-0.90.90.80.70.90.5-0.50.60.50.10.6
Bone: endosteal perimeter0.10.20.8-0.6-0.20.1-0.6-0.30.0-0.2-0.80.00.40.10.5-0.50.60.4-0.00.6-0.10.0-0.1-0.2-0.90.1
Epididymis fat weight0.62.03.9-2.0-1.91.9-1.6-1.61.7-1.5-1.1-1.4-1.5-1.1-1.61.6-1.4-1.6-1.2-1.4-0.81.0-1.0-0.9-0.2-1.0
Delta time in closed arm before/after self-admin1.71.63.00.50.7-1.00.71.1-1.11.00.91.21.51.31.7-1.71.51.71.31.41.2-1.21.31.2-1.11.5
Delta time in open arm before/after self-admin0.80.81.7-1.3-1.31.3-1.0-1.11.1-1.0-0.7-0.9-0.8-0.9-0.90.9-0.5-0.8-0.8-0.6-0.80.8-0.8-0.7-0.7-0.6
Diff in mean of infusions in LGA sessions6.47.79.63.13.1-2.92.93.0-3.13.13.13.02.83.02.6-2.62.42.52.92.62.9-2.72.82.8-0.52.7
Delay discount exponential model param1.51.72.5-1.3-1.41.4-1.2-1.31.4-1.4-1.0-1.4-1.6-1.5-1.41.4-1.1-1.3-1.3-1.1-1.41.6-1.3-1.20.5-1.2
Extinction: sum of active levers before priming0.20.20.80.50.80.10.40.1-0.40.60.20.3-0.30.3-0.60.6-0.6-0.70.4-0.80.50.10.40.40.9-0.0
Active lever presses in extinction session 60.10.10.60.20.30.3-0.2-0.2-0.10.20.10.0-0.30.0-0.40.4-0.2-0.30.0-0.30.20.40.00.00.8-0.1
Bone: final force0.10.20.4-0.5-0.20.4-0.4-0.40.4-0.4-0.6-0.5-0.3-0.5-0.20.2-0.4-0.5-0.5-0.4-0.40.4-0.6-0.60.3-0.6
Bone: final moment0.00.10.40.10.3-0.00.0-0.00.0-0.0-0.2-0.2-0.1-0.2-0.20.2-0.2-0.4-0.2-0.2-0.10.1-0.2-0.30.6-0.4
Food consumed during 24 hour testing period1.01.42.11.11.4-0.60.40.7-1.51.40.51.51.41.11.2-1.21.31.31.51.31.2-1.11.31.2-1.01.3
Glucose0.20.41.2-0.7-0.90.5-0.9-0.60.5-0.7-0.6-0.4-0.2-0.60.0-0.00.60.2-0.50.6-0.60.6-0.5-0.6-1.1-0.1
Heart weight0.20.31.10.70.8-0.51.00.6-0.50.50.70.30.30.30.3-0.3-0.00.50.3-0.10.3-0.20.20.21.10.0
Delay discount hyperbolic model param2.12.43.2-1.6-1.71.6-1.4-1.51.7-1.7-1.3-1.7-1.8-1.7-1.61.6-1.3-1.4-1.6-1.3-1.61.8-1.5-1.50.7-1.5
Intermittent access intake day 1-15 change1.42.910.60.60.4-1.30.61.1-1.10.70.81.31.90.92.4-2.43.32.61.13.20.5-0.80.90.7-3.21.7
Intermittent access intake escalation1.63.310.80.80.6-1.50.91.3-1.31.00.91.52.01.22.5-2.53.32.71.33.20.8-1.11.11.0-2.91.9
Intermittent access intake escalation 23.54.010.71.01.0-1.71.11.6-1.71.41.21.82.31.52.7-2.73.32.81.73.31.2-1.51.51.4-2.82.2
Intermitt. access day 1 inactive lever presses0.41.63.31.21.4-1.31.21.4-1.41.61.61.40.91.60.3-0.30.20.11.50.21.8-1.81.71.70.41.3
Intermitt. access day 15 inactive lever presses0.00.10.2-0.1-0.3-0.20.20.10.1-0.1-0.1-0.00.2-0.00.4-0.40.40.4-0.00.4-0.2-0.2-0.0-0.00.10.2
Intermitt. access escalation Index2.02.96.2-2.2-2.51.6-1.5-1.72.1-2.1-1.9-1.9-1.6-1.9-1.21.2-0.9-1.1-1.8-0.9-2.01.8-1.8-1.7-1.0-1.4
Intermittent access day 1 total infusions0.20.30.90.80.8-0.10.40.3-0.50.60.60.40.10.5-0.20.2-0.7-0.30.5-0.70.7-0.50.50.60.90.2
Intermittent access day 15 total infusions0.71.12.40.70.6-0.80.50.7-0.90.80.61.01.20.91.3-1.31.51.31.01.50.8-0.90.90.9-1.31.2
Intermittent access terminal intake (last 3 days)1.92.54.01.41.4-1.51.21.4-1.61.51.31.61.91.51.9-1.92.02.01.62.01.4-1.51.41.4-1.21.7
Intermittent access total infusions0.00.00.10.30.30.00.0-0.0-0.20.20.00.20.20.20.1-0.1-0.20.10.2-0.10.3-0.20.20.2-0.10.1
Intermittent access day 1 locomotion0.70.81.51.21.1-0.91.01.0-1.01.11.11.00.71.00.5-0.50.30.51.00.31.1-0.81.11.10.30.9
Intermittent access day 15 total locomotion2.44.36.51.92.0-2.21.92.1-2.22.01.92.22.32.02.3-2.32.52.32.12.41.9-1.91.91.8-1.32.1
Intermittent access total locomotion2.53.03.71.81.9-1.81.71.7-1.91.91.51.91.81.91.7-1.71.61.71.91.61.8-1.71.81.7-0.51.8
Intermittent access standard deviation0.71.53.90.80.6-1.00.31.0-1.00.80.91.11.50.91.8-1.81.82.01.11.90.8-1.00.90.9-1.21.3
Left kidney weight0.00.20.4-0.50.20.5-0.6-0.4-0.20.4-0.40.3-0.00.4-0.40.4-0.6-0.50.5-0.50.6-0.20.50.5-0.20.3
Right kidney weight0.41.93.41.31.7-1.11.51.3-1.51.81.61.51.11.60.8-0.8-0.00.91.7-0.01.7-1.31.81.81.21.3
Cocaine induced anxiety1.21.73.11.21.6-1.21.31.3-1.51.71.31.51.11.60.6-0.60.10.41.60.11.8-1.61.71.70.61.3
Post-drug Anxiety0.20.30.90.30.5-0.41.00.4-0.50.70.50.50.20.60.1-0.1-0.2-0.10.7-0.20.6-0.50.70.80.40.6
Baseline Anxiety0.10.20.6-0.4-0.70.3-0.2-0.40.4-0.5-0.2-0.3-0.2-0.50.0-0.00.40.2-0.30.4-0.50.5-0.3-0.3-0.8-0.1
Tail length5.220.332.5-5.6-5.75.3-5.5-5.45.2-5.3-5.2-4.8-4.0-4.8-3.43.4-3.2-3.1-4.7-3.0-4.64.0-4.5-4.5-1.6-4.0
Length with tail1.66.811.8-3.4-3.23.3-3.1-3.33.0-2.9-2.9-2.7-2.2-2.6-2.02.0-2.4-1.9-2.5-2.3-2.42.2-2.4-2.3-1.4-2.3
Length without tail0.51.63.00.61.2-0.60.70.8-1.31.40.91.41.61.61.3-1.30.31.41.60.21.7-1.41.61.7-0.61.4
Times rat made contact with spout0.50.51.2-0.6-0.70.5-0.4-0.60.8-0.8-0.5-0.9-0.5-1.00.0-0.0-0.7-0.0-0.9-0.7-1.10.9-0.9-0.90.8-0.9
Lifetime Intake0.00.10.20.30.40.00.10.0-0.20.30.10.20.10.20.0-0.0-0.40.00.2-0.40.3-0.20.20.30.30.1
Liver weight, left0.71.12.3-0.6-0.41.0-0.7-0.90.8-0.7-0.6-1.0-1.4-1.2-1.51.5-1.3-1.4-1.0-1.3-1.11.3-1.0-1.00.3-1.2
Liver weight, right0.20.40.9-0.5-0.20.7-0.5-0.60.4-0.4-0.2-0.6-0.9-0.7-1.01.0-0.7-1.0-0.6-0.7-0.50.7-0.7-0.70.4-0.7
Locomotor activity0.20.31.40.80.7-1.01.00.8-0.40.20.30.10.50.10.7-0.70.60.7-0.20.5-0.1-0.3-0.2-0.41.2-0.3
Locomotor testing distance0.71.22.81.51.2-1.71.61.5-0.90.71.00.71.10.61.4-1.41.21.50.41.20.4-0.90.30.11.30.3
Locomotor testing rearing0.30.64.31.10.9-1.11.31.0-0.60.50.80.30.40.40.4-0.40.10.30.20.10.3-0.60.20.22.1-0.0
Locomotion in novel chamber3.84.87.92.82.8-2.32.22.3-2.62.62.32.52.12.41.9-1.91.51.82.41.52.4-2.02.32.3-0.12.1
Locomotion in novel chamber post-restriction0.10.10.5-0.4-0.30.4-0.4-0.50.2-0.3-0.7-0.2-0.1-0.3-0.10.10.1-0.1-0.20.1-0.20.2-0.3-0.3-0.4-0.2
Fecal boli incidents, locomotor time 10.30.41.1-0.8-0.80.6-0.2-0.50.8-0.7-0.4-0.7-0.6-0.6-0.60.6-0.8-0.6-0.7-0.8-0.40.4-0.5-0.51.0-0.6
Change in fecal boli incidents, locomotor task2.02.02.71.41.4-1.61.21.5-1.51.41.41.51.61.41.6-1.61.31.61.41.31.3-1.61.41.3-0.31.4
Time >=10cm from walls, locomotor time 11.31.42.1-0.9-0.91.1-0.6-1.11.2-1.1-1.1-1.3-1.3-1.2-1.21.2-1.4-1.2-1.3-1.4-1.31.3-1.3-1.20.2-1.4
Bouts of movement, locomotor time 14.14.76.5-2.4-2.52.0-1.6-2.22.5-2.6-2.2-2.5-2.1-2.4-1.91.9-1.8-1.7-2.5-1.7-2.32.2-2.5-2.5-0.1-2.3
Total resting periods, locomotor time 14.34.87.2-2.5-2.62.1-1.8-2.32.6-2.7-2.3-2.6-2.0-2.5-1.71.7-1.4-1.5-2.6-1.4-2.32.2-2.6-2.6-0.5-2.3
Rest time, locomotor task time 10.50.66.9-1.1-1.20.6-0.6-0.50.7-0.8-0.4-0.5-0.3-0.4-0.30.30.3-0.1-0.40.4-0.20.3-0.4-0.4-2.60.0
Distance moved, locomotor task time 10.71.15.50.20.20.40.3-0.30.3-0.1-0.2-0.5-1.3-0.5-1.61.6-1.9-1.7-0.4-1.9-0.60.9-0.4-0.22.4-0.9
Vertical activity count, locomotor time 10.20.42.30.80.8-0.10.60.2-0.20.30.2-0.1-0.6-0.1-0.80.8-1.2-0.9-0.1-1.2-0.20.3-0.1-0.01.5-0.5
Time >=10cm from walls, locomotor time 20.20.30.50.60.6-0.50.30.5-0.60.60.70.60.50.70.4-0.40.10.30.60.10.6-0.70.60.6-0.40.5
Bouts of movement, locomotor time 20.10.10.4-0.1-0.2-0.1-0.0-0.00.3-0.3-0.1-0.3-0.4-0.4-0.20.2-0.30.0-0.3-0.3-0.60.7-0.4-0.40.7-0.4
Total resting periods, locomotor time 20.10.20.4-0.2-0.30.0-0.1-0.10.4-0.4-0.2-0.4-0.4-0.5-0.30.3-0.5-0.1-0.4-0.5-0.60.7-0.4-0.40.6-0.4
Rest time, locomotor task time 21.11.42.1-1.2-1.31.5-1.3-1.41.3-1.1-1.1-1.1-1.1-1.1-1.31.3-1.2-1.4-1.0-1.1-0.70.9-0.9-0.8-1.1-0.9
Distance moved, locomotor task time 20.91.01.71.21.3-1.31.21.3-1.21.31.21.20.61.10.5-0.50.80.51.20.70.9-0.61.11.1-0.11.0
Vertical activity count, locomotor time 21.41.92.81.31.4-1.71.61.6-1.51.51.61.51.21.51.2-1.21.41.21.51.41.1-1.11.31.3-1.11.5
Light reinforcement 10.41.11.91.01.2-1.11.11.1-1.11.00.91.01.30.91.4-1.41.21.40.91.20.7-1.00.80.60.20.8
Light reinforcement 20.71.11.61.11.2-1.21.21.2-1.11.11.01.01.20.91.3-1.30.81.21.00.80.8-1.10.90.80.60.8
Bone: marrow area0.30.60.90.81.0-0.90.80.8-0.90.80.70.80.70.60.9-0.90.80.80.70.80.5-0.50.60.60.20.6
Bone: maximum diameter0.10.21.2-0.50.10.5-0.6-0.50.2-0.2-1.1-0.3-0.3-0.2-0.40.4-0.7-0.7-0.4-0.7-0.20.3-0.4-0.50.4-0.6
Bone: maximum force0.20.40.80.60.8-0.70.70.7-0.70.60.50.60.80.50.9-0.90.50.60.50.50.6-0.80.50.40.50.4
Bone: maximum moment0.50.91.71.21.3-1.21.21.1-1.11.00.90.91.00.90.9-0.90.60.60.80.60.9-1.00.80.70.80.6
Mean time between licks in bursts0.10.31.10.20.10.00.2-0.00.3-0.30.3-0.5-0.9-0.7-0.90.9-0.4-1.0-0.7-0.4-0.70.7-0.7-0.70.4-0.8
Mean num. licks in bursts1.42.18.1-0.2-0.31.0-0.3-0.91.0-0.6-0.6-1.1-1.6-1.0-1.81.8-2.8-2.0-0.9-2.8-0.81.1-0.8-0.62.8-1.4
Cd content in liver2.12.34.7-2.0-2.21.8-1.7-1.71.8-1.8-1.4-1.7-1.4-1.6-1.11.1-0.9-1.0-1.6-0.9-1.61.6-1.5-1.4-1.0-1.2
Co content in liver3.33.95.8-2.4-2.12.4-2.3-2.32.1-2.0-2.1-2.0-2.0-1.8-1.91.9-2.0-1.8-1.8-2.0-1.72.1-1.8-1.7-0.6-1.8
Cu content in liver0.70.81.8-0.8-1.00.7-0.9-0.91.0-1.2-1.2-1.1-0.7-1.1-0.60.6-0.3-0.5-1.2-0.3-1.20.7-1.3-1.3-0.1-1.1
Fe content in liver0.10.10.5-0.1-0.20.1-0.3-0.20.2-0.3-0.3-0.3-0.3-0.5-0.10.10.3-0.0-0.40.3-0.60.7-0.5-0.5-0.4-0.3
K content in liver0.60.51.60.50.7-0.70.60.7-0.70.80.50.80.71.20.3-0.30.20.20.80.21.2-1.20.90.9-0.10.7
Mg content in liver0.50.51.10.50.6-0.90.70.8-0.60.60.50.61.00.90.7-0.70.60.80.50.60.9-1.00.60.5-0.00.6
Mn content in liver2.32.53.41.81.8-1.81.61.8-1.71.51.51.51.81.51.8-1.81.81.71.41.81.4-1.41.31.1-0.61.3
Na content in liver0.91.05.11.61.3-1.51.61.3-0.80.91.00.5-0.10.6-0.80.8-0.4-0.70.4-0.40.6-0.60.50.52.30.0
Rb content in liver0.10.10.60.70.7-0.30.50.3-0.30.20.30.1-0.2-0.0-0.30.3-0.2-0.3-0.1-0.20.00.1-0.1-0.20.2-0.3
Se content in liver0.40.40.8-0.6-0.90.6-0.7-0.60.7-0.9-0.6-0.7-0.6-0.8-0.40.40.2-0.2-0.80.2-0.80.7-0.8-0.9-0.6-0.6
Sr content in liver3.73.25.2-0.9-1.21.3-1.0-1.31.7-1.7-1.1-1.9-2.3-1.9-2.22.2-1.8-2.2-2.0-1.8-1.92.1-1.9-1.91.4-2.1
Zn content in liver0.20.30.6-0.7-0.70.4-0.4-0.40.6-0.6-0.5-0.6-0.5-0.3-0.80.8-0.6-0.5-0.5-0.6-0.20.1-0.4-0.40.4-0.4
Bone: minimum diameter0.20.30.80.20.6-0.40.10.3-0.60.5-0.00.60.90.60.9-0.90.50.40.50.50.7-0.80.50.4-0.20.5
Time in familiar zone, hab. session 10.10.10.8-0.4-0.50.4-0.5-0.30.2-0.2-0.4-0.00.10.10.1-0.10.20.10.10.20.20.00.10.1-0.90.2
Time in novel zone, hab. session 10.10.10.2-0.00.1-0.1-0.00.00.0-0.2-0.1-0.20.1-0.30.3-0.30.30.3-0.30.3-0.30.3-0.4-0.40.2-0.3
Total zone transitions, hab. session 10.81.11.61.10.8-1.01.11.1-0.91.01.11.01.11.31.1-1.10.80.91.00.81.2-1.11.11.1-0.11.1
Total locomotion distance, hab. session 10.40.61.5-1.0-1.20.9-0.9-0.91.0-1.1-0.8-0.9-0.4-0.7-0.00.0-0.2-0.4-0.9-0.2-0.70.6-0.9-0.9-0.5-0.7
Locomotion velocity, hab. session 10.60.81.7-1.1-1.31.0-0.9-1.01.2-1.2-0.8-1.1-0.8-0.9-0.50.5-0.5-0.8-1.1-0.5-1.00.7-1.1-1.1-0.3-0.9
Time in familiar zone, hab. session 20.20.21.0-0.8-0.50.6-0.9-0.60.2-0.2-0.9-0.00.20.20.1-0.10.10.10.10.10.2-0.10.10.1-1.00.2
Time in novel zone, hab. session 20.20.20.50.60.3-0.40.60.40.0-0.10.7-0.3-0.6-0.6-0.50.5-0.1-0.5-0.4-0.1-0.60.5-0.5-0.50.7-0.5
Total zone transitions, hab. session 20.00.10.3-0.3-0.20.3-0.4-0.40.2-0.3-0.5-0.20.1-0.00.2-0.2-0.20.0-0.2-0.2-0.1-0.1-0.2-0.2-0.0-0.2
Total locomotion distance, hab. session 20.91.23.0-1.6-1.41.5-1.7-1.51.2-1.3-1.7-1.1-0.5-0.9-0.20.2-0.4-0.5-1.0-0.4-1.00.8-1.1-1.1-1.0-0.9
Locomotion velocity, hab. session 20.91.12.9-1.6-1.31.5-1.7-1.51.2-1.3-1.6-1.1-0.5-0.8-0.20.2-0.5-0.5-1.0-0.5-0.90.8-1.0-1.1-0.9-0.9
Novel to familiar place preference ratio0.10.10.30.40.3-0.30.30.3-0.20.20.40.2-0.20.0-0.50.50.1-0.30.10.10.2-0.10.10.10.30.1
Novelty place preference0.00.00.30.20.1-0.10.10.1-0.0-0.00.2-0.0-0.3-0.2-0.60.60.1-0.3-0.10.1-0.00.1-0.1-0.10.1-0.1
Time in novel zone, NPP test0.10.10.30.30.1-0.20.10.2-0.0-0.00.2-0.0-0.4-0.3-0.60.60.3-0.3-0.10.3-0.10.2-0.2-0.2-0.1-0.1
Total zone transitions, NPP test0.10.20.30.50.3-0.40.40.4-0.30.40.30.30.40.50.5-0.50.10.40.40.10.4-0.40.40.40.30.3
Total locomotion distance, NPP test0.10.10.4-0.5-0.40.5-0.6-0.50.3-0.4-0.6-0.3-0.0-0.10.2-0.2-0.1-0.0-0.3-0.1-0.20.3-0.3-0.3-0.3-0.2
Locomotion velocity, NPP test0.00.00.2-0.2-0.10.2-0.4-0.30.1-0.1-0.4-0.10.20.10.4-0.40.00.2-0.10.00.00.0-0.1-0.1-0.2-0.1
Intraocular pressure0.10.10.70.3-0.1-0.10.50.30.10.00.8-0.0-0.10.1-0.30.3-0.2-0.0-0.0-0.10.1-0.20.10.10.70.1
Delta distance traveled before/after self-admin0.10.10.40.50.4-0.10.60.2-0.20.30.40.1-0.10.1-0.20.2-0.3-0.30.1-0.30.2-0.10.10.20.6-0.1
Delta ambulatory time before/after self-admin0.10.11.20.30.20.20.3-0.20.00.10.1-0.1-0.3-0.0-0.50.5-0.7-0.5-0.0-0.70.00.2-0.00.01.1-0.3
Parametrial fat weight2.96.911.3-3.0-2.83.4-3.0-3.12.8-2.5-2.5-2.6-3.0-2.5-2.92.9-2.6-2.9-2.3-2.6-2.22.6-2.2-2.0-0.0-2.2
Pavlov. Cond. lever latency0.20.30.90.50.4-0.80.60.6-0.50.30.40.40.70.20.9-0.91.00.80.21.00.2-0.30.10.1-0.10.3
Pavlov. Cond. magazine entry latency0.10.10.40.00.3-0.10.00.1-0.30.40.20.40.30.50.2-0.20.20.20.50.20.4-0.50.50.5-0.60.5
Pavlov. Cond. change in total contacts0.30.31.8-1.1-0.80.9-1.0-0.80.4-0.3-0.6-0.1-0.2-0.0-0.50.5-0.3-0.40.0-0.30.2-0.10.10.1-1.30.2
Pavlov. Cond. index score0.10.10.3-0.5-0.20.5-0.5-0.40.1-0.0-0.3-0.0-0.30.1-0.60.6-0.5-0.50.1-0.50.1-0.00.10.2-0.30.0
Pavlov. Cond. latency score0.10.10.3-0.3-0.10.4-0.4-0.30.00.1-0.20.1-0.20.2-0.50.5-0.5-0.50.2-0.50.2-0.20.30.3-0.30.1
Pavlov. Cond. lever contacts0.30.30.8-0.6-0.50.8-0.7-0.60.5-0.4-0.4-0.4-0.7-0.3-0.90.9-0.7-0.8-0.3-0.7-0.20.4-0.2-0.2-0.2-0.3
Pavlov. Cond. magazine entry number0.60.81.3-0.6-0.90.7-0.6-0.71.0-1.0-0.7-1.1-1.0-1.1-0.70.7-0.7-0.8-1.1-0.7-1.11.1-1.1-1.10.6-1.1
Pavlov. Cond. intertrial magazine entries1.61.93.2-1.1-1.41.1-0.9-1.11.5-1.6-1.1-1.6-1.5-1.6-1.41.4-0.8-1.3-1.8-0.8-1.51.4-1.7-1.80.3-1.6
Pavlov. Cond. lever-magazine prob. diff.0.10.20.4-0.6-0.30.6-0.6-0.50.3-0.2-0.4-0.2-0.4-0.1-0.60.6-0.5-0.6-0.1-0.5-0.00.10.00.1-0.3-0.1
Pavlov. Cond. response bias0.00.00.1-0.3-0.10.4-0.3-0.30.10.0-0.1-0.0-0.20.1-0.30.3-0.4-0.20.1-0.40.1-0.00.10.2-0.20.1
Pavlov. Cond. lever latency0.50.72.3-1.4-1.11.0-1.2-1.00.8-0.8-1.0-0.6-0.6-0.5-0.80.8-0.3-0.9-0.6-0.3-0.40.4-0.5-0.5-1.5-0.3
Pavlov. Cond. magazine entry latency0.40.51.90.20.2-0.40.20.4-0.50.40.40.51.00.71.4-1.40.91.30.60.90.5-0.50.50.5-0.50.7
Pavlov. Cond. change in total contacts0.10.11.40.70.5-0.40.50.4-0.30.30.30.10.20.10.4-0.4-0.00.30.1-0.0-0.00.10.00.01.2-0.1
Pavlov. Cond. index score0.30.51.81.10.9-0.81.00.8-0.60.60.90.50.50.50.8-0.80.10.70.40.10.3-0.20.40.41.30.2
Pavlov. Cond. latency score0.30.41.21.00.7-0.70.90.8-0.60.60.90.50.50.50.8-0.80.20.70.50.20.4-0.30.40.51.10.3
Pavlov. Cond. lever contacts0.60.82.11.41.2-1.01.21.1-0.90.91.00.70.80.61.0-1.00.41.00.60.40.5-0.50.60.61.40.4
Pavlov. Cond. magazine entry number0.20.20.7-0.5-0.50.4-0.4-0.40.4-0.4-0.4-0.3-0.5-0.3-0.90.9-0.3-0.7-0.3-0.3-0.30.1-0.3-0.3-0.4-0.3
Pavlov. Cond. intertrial magazine entries0.00.00.10.1-0.0-0.10.20.10.0-0.00.1-0.0-0.2-0.1-0.30.3-0.0-0.2-0.0-0.0-0.00.0-0.0-0.00.3-0.0
Pavlov. Cond. lever-magazine prob. diff.0.40.51.91.20.9-0.81.00.8-0.60.70.90.50.50.50.7-0.70.10.60.40.10.4-0.20.40.41.40.2
Pavlov. Cond. response bias0.71.02.21.51.3-1.21.31.2-1.01.01.00.81.00.81.2-1.20.51.20.80.50.6-0.60.70.71.50.5
Time in closed arm before self-admin0.81.12.2-0.8-0.90.9-0.5-0.91.0-0.9-0.8-1.0-1.3-1.0-1.31.3-1.5-1.4-1.0-1.3-0.90.9-0.9-0.80.8-1.0
Time in closed arm after self-admin0.10.10.3-0.3-0.30.1-0.1-0.10.3-0.2-0.2-0.3-0.5-0.2-0.50.5-0.6-0.5-0.2-0.4-0.20.3-0.2-0.10.6-0.2
Time in open arm before self-admin2.83.15.22.32.3-2.12.02.0-2.01.91.71.81.81.81.7-1.71.51.71.61.51.7-1.61.51.40.51.4
Time in open arm after self-admin0.00.00.10.00.00.20.1-0.1-0.00.00.2-0.00.20.10.2-0.2-0.00.30.0-0.10.10.00.00.00.2-0.0
Bone: periosteal estimation0.00.10.3-0.20.20.1-0.2-0.2-0.00.0-0.5-0.1-0.0-0.20.0-0.0-0.3-0.3-0.1-0.3-0.10.1-0.1-0.20.6-0.3
Bone: periosteal perimeter1.11.93.8-1.7-1.31.6-1.7-1.61.4-1.4-1.9-1.4-1.2-1.4-1.11.1-1.1-1.3-1.4-1.1-1.31.3-1.5-1.5-0.0-1.5
Bone: post-yield work0.10.10.20.20.3-0.30.30.3-0.30.40.30.40.40.40.4-0.40.20.30.40.20.4-0.40.40.40.20.4
Progressive ratio test 1 active lever presses0.10.21.20.20.20.3-0.2-0.20.10.0-0.0-0.1-0.20.0-0.40.4-0.9-0.3-0.0-0.90.20.10.00.11.1-0.3
Progressive ratio test 1 breakpoint0.10.21.60.40.40.10.0-0.0-0.10.20.10.0-0.10.2-0.30.3-0.9-0.30.1-0.80.30.00.10.21.3-0.2
Progressive ratio test 1 inactive lever presses0.20.20.8-0.1-0.10.5-0.6-0.40.3-0.2-0.1-0.3-0.5-0.2-0.80.8-0.7-0.9-0.3-0.8-0.00.2-0.2-0.20.1-0.4
Progressive ratio test 2 active lever presses0.20.20.70.70.8-0.40.60.4-0.60.70.40.50.20.5-0.10.1-0.0-0.10.5-0.10.6-0.40.50.5-0.30.3
Progressive ratio test 2 breakpoint0.20.30.90.80.9-0.50.80.5-0.70.70.50.50.20.5-0.10.1-0.0-0.10.5-0.10.6-0.40.50.5-0.10.3
Progressive ratio test 2 inactive lever presses0.30.40.60.70.7-0.70.60.7-0.70.80.70.70.60.60.5-0.50.60.40.80.40.6-0.70.70.7-0.40.7
Incentive Sensitization - Responses0.20.21.00.80.8-0.61.00.5-0.50.50.30.30.10.2-0.20.20.4-0.30.10.30.2-0.10.10.0-0.9-0.0
Incentive Sensitization - Breakpoint0.10.21.00.70.7-0.61.00.4-0.40.40.20.2-0.10.1-0.30.30.3-0.40.00.20.1-0.0-0.0-0.1-0.8-0.1
Sum of active levers in priming session hrs 5-60.10.10.70.50.6-0.30.60.2-0.30.30.20.1-0.10.0-0.10.1-0.0-0.00.1-0.10.10.20.0-0.00.8-0.1
Progressive ratio1.62.64.0-1.6-1.61.8-2.0-1.81.7-1.7-1.9-1.6-1.6-1.7-1.61.6-0.9-1.6-1.7-0.9-1.61.8-1.7-1.7-0.6-1.6
Food seeking constrained by brief footshock0.70.93.80.40.2-0.90.70.8-0.60.30.30.60.90.31.4-1.42.01.60.41.90.1-0.10.30.1-1.30.7
Seeking ratio, punishment vs. effort1.11.62.61.01.0-1.41.61.4-1.21.31.31.31.31.21.5-1.51.01.51.41.01.1-1.21.31.3-0.11.4
Retroperitoneal fat weight2.912.218.7-4.2-4.14.3-3.8-4.03.9-3.6-3.0-3.6-3.7-3.2-3.93.9-3.5-3.8-3.2-3.6-2.83.1-2.9-2.7-0.1-3.0
Reaction time number correct0.40.72.9-0.6-0.70.2-0.8-0.40.5-0.8-0.8-0.6-0.2-0.90.2-0.21.30.4-0.81.3-1.10.9-1.0-1.1-1.7-0.4
Reaction time mean minus median1.12.94.81.91.9-2.02.22.1-1.81.92.11.81.41.81.0-1.01.20.91.71.21.8-1.91.81.81.01.6
Reaction time mean minus median AUC0.71.94.31.71.7-1.92.11.9-1.51.51.81.31.01.30.8-0.81.10.71.21.01.2-1.51.21.21.21.0
Reaction time num false alarms0.20.32.4-0.4-0.40.3-0.7-0.30.0-0.2-0.30.10.4-0.00.6-0.60.90.60.00.9-0.0-0.1-0.0-0.1-1.60.3
Reaction time num false alarms AUC0.20.32.0-0.1-0.20.1-0.5-0.1-0.20.0-0.20.30.60.10.7-0.71.00.70.21.00.2-0.30.20.1-1.40.5
Reaction time trials correct on left0.40.72.9-0.6-0.70.2-0.8-0.40.5-0.8-0.8-0.6-0.2-0.90.2-0.21.30.4-0.81.3-1.10.9-1.0-1.1-1.7-0.4
Reaction time trials on left0.40.73.1-0.7-0.70.2-0.8-0.40.5-0.8-0.8-0.5-0.2-0.90.2-0.21.30.4-0.81.3-1.10.9-1.0-1.1-1.8-0.4
Reaction time mean0.20.31.6-0.5-0.50.5-0.2-0.40.6-0.4-0.3-0.5-0.6-0.3-0.70.7-1.0-0.7-0.4-0.9-0.20.2-0.3-0.21.3-0.5
Reaction time mean AUC0.30.53.9-0.4-0.30.40.1-0.30.5-0.2-0.1-0.5-0.7-0.2-0.80.8-1.3-0.9-0.3-1.2-0.20.2-0.2-0.12.0-0.5
Median of all reaction times1.21.83.1-1.4-1.41.5-1.1-1.41.5-1.3-1.2-1.4-1.4-1.1-1.41.4-1.8-1.4-1.2-1.7-1.11.1-1.1-1.01.1-1.3
Reaction time omissions0.10.10.7-0.8-0.60.5-0.5-0.40.4-0.4-0.3-0.3-0.3-0.2-0.30.30.0-0.3-0.30.1-0.20.1-0.3-0.3-0.5-0.2
Reaction time false alarm rate0.10.20.40.00.00.2-0.3-0.1-0.20.30.10.40.50.50.5-0.50.20.40.50.20.6-0.60.60.6-0.50.6
Reaction time premature initiation rate0.70.91.71.31.1-1.11.31.2-1.01.11.30.90.71.10.5-0.50.10.40.90.21.1-1.11.01.00.80.8
Reaction time premature initiations0.20.41.00.90.7-1.00.91.0-0.70.60.80.60.50.60.4-0.40.60.40.50.70.4-0.60.50.40.00.5
Std. dev. reaction times0.61.02.01.11.0-1.21.41.3-1.01.21.41.00.71.20.3-0.30.50.21.00.51.2-1.21.21.20.80.9
Reaction time trials completed0.40.73.1-0.7-0.70.2-0.8-0.40.5-0.8-0.8-0.5-0.2-0.90.2-0.21.30.4-0.81.3-1.10.9-1.0-1.1-1.8-0.4
Reaction time trials AUC0.61.13.7-1.0-1.10.5-1.1-0.70.8-1.2-1.1-0.8-0.4-1.20.0-0.01.20.3-1.11.2-1.41.2-1.3-1.4-1.9-0.7
Run reversals in cocaine runway, females0.30.31.0-0.7-1.00.3-0.8-0.40.7-0.9-0.6-0.6-0.2-0.70.2-0.20.60.4-0.70.5-0.70.6-0.7-0.8-0.1-0.4
Run reversals in cocaine runway, males0.30.30.50.20.1-0.50.50.6-0.40.40.70.50.60.60.6-0.60.50.60.50.50.7-0.70.60.6-0.00.6
Latency to leave start box in cocaine runway0.80.92.81.21.4-0.61.10.9-1.01.21.50.80.21.0-0.20.2-0.7-0.30.9-0.71.0-0.91.01.11.70.5
Latency to leave start box in cocaine runway, F0.60.73.01.01.3-0.61.10.8-0.81.01.20.60.20.9-0.10.1-0.6-0.30.7-0.60.9-0.90.80.81.70.3
Latency to leave start box in cocaine runway, M0.40.41.30.90.9-0.30.50.6-0.70.91.10.70.20.70.0-0.0-0.2-0.00.8-0.20.8-0.50.80.90.40.6
Std. dev. time between licks in bursts0.40.61.60.70.8-1.21.01.0-0.70.50.70.50.70.40.9-0.91.30.80.31.30.1-0.50.20.0-0.20.3
Total sessions with >9 infusions0.40.52.21.21.1-0.91.20.9-0.80.80.70.60.40.60.4-0.4-0.10.40.5-0.10.6-0.40.50.51.50.3
Short access day 1 total inactive lever presses0.60.74.31.31.1-0.91.51.0-0.70.91.10.50.10.6-0.20.2-0.5-0.20.6-0.60.7-0.40.60.72.10.2
Short access day 10 total inactive lever presses0.10.40.60.50.6-0.60.50.7-0.70.70.70.70.50.60.3-0.30.70.20.70.70.6-0.80.70.6-0.40.7
Short access day 1 total infusions0.30.42.11.11.0-0.91.40.9-0.60.70.50.40.20.30.2-0.2-0.10.20.3-0.20.3-0.10.30.31.40.0
Short access day 10 total infusions0.10.22.10.30.3-0.20.60.2-0.00.10.1-0.1-0.20.0-0.20.2-0.8-0.20.0-0.80.10.00.00.11.4-0.2
Short access total infusions0.30.42.21.00.9-0.61.00.7-0.60.70.50.50.30.50.3-0.3-0.40.30.5-0.40.6-0.40.50.51.50.2
Short access day 1 locomotion1.01.23.51.31.2-1.61.91.4-1.10.90.91.01.10.81.3-1.31.41.30.81.40.7-0.60.60.5-0.30.8
Short access day 10 total locomotion1.73.14.22.02.0-1.92.01.8-2.02.01.81.91.71.91.6-1.61.01.51.91.21.9-1.81.91.90.31.7
Short access total locomotion1.62.03.31.81.7-1.81.81.7-1.61.51.51.51.31.41.3-1.31.11.21.41.11.3-1.11.31.30.31.2
One hour access (0.3 mA shock)0.10.10.5-0.6-0.50.6-0.5-0.70.3-0.2-0.6-0.1-0.00.0-0.10.1-0.3-0.10.0-0.30.20.00.10.1-0.70.1
Compulsive drug intake1.11.32.0-0.9-1.01.1-0.8-1.11.2-1.1-1.3-1.2-1.1-1.1-1.01.0-1.3-1.2-1.2-1.4-1.01.0-1.1-1.11.1-1.3
One hour access (shock baseline)0.10.11.2-0.1-0.00.1-0.2-0.1-0.20.1-0.10.30.40.20.4-0.40.40.40.30.40.3-0.10.30.3-1.10.4
Social response proportion0.30.32.4-0.6-0.40.4-0.9-0.50.1-0.2-0.70.10.50.00.7-0.70.70.70.10.7-0.1-0.10.0-0.1-1.50.4
Social responses0.40.51.1-0.10.1-0.2-0.20.2-0.50.4-0.10.61.00.71.0-1.01.01.00.61.00.7-0.90.60.5-1.00.8
Social time1.21.72.8-1.5-1.31.5-1.6-1.61.3-1.4-1.7-1.3-1.2-1.4-1.01.0-0.9-1.0-1.3-0.9-1.41.2-1.4-1.4-0.3-1.3
Soleus weight0.20.61.30.60.9-0.90.70.8-0.90.70.70.80.80.60.9-0.91.10.70.61.10.4-0.90.50.4-0.60.6
Bone: stiffness0.10.10.4-0.6-0.20.4-0.4-0.40.2-0.2-0.6-0.20.3-0.10.6-0.6-0.20.3-0.1-0.2-0.10.0-0.2-0.20.2-0.2
Tibialis anterior weight0.31.22.90.61.0-1.00.40.9-1.21.10.61.31.10.81.0-1.01.70.71.21.70.9-1.11.00.9-1.41.3
Time to tail flick, vehicle, before self-admin0.30.30.80.70.9-0.50.40.6-0.70.80.90.70.40.70.3-0.3-0.10.30.70.20.6-0.40.70.7-0.50.5
Time to tail flick, vehicle, after self-admin0.50.71.8-0.9-0.91.3-1.0-1.10.9-0.7-0.5-0.7-0.6-0.5-0.90.9-1.1-1.1-0.6-1.3-0.3-0.0-0.4-0.3-0.1-0.6
Time to tail flick, test, before self-admin0.40.50.8-0.7-0.70.30.3-0.40.8-0.8-0.4-0.8-0.7-0.8-0.50.5-0.6-0.5-0.9-0.6-0.90.5-0.9-0.90.3-0.8
Time to tail flick, test, after self-admin0.00.00.40.0-0.00.10.20.1-0.10.10.30.10.00.2-0.10.1-0.2-0.20.2-0.10.3-0.10.20.3-0.60.2
Delta time to tail flick, vehicle, before/after SA1.41.32.4-1.4-1.61.4-1.1-1.31.4-1.3-1.2-1.3-0.9-1.1-0.90.9-0.9-1.0-1.2-1.3-0.90.5-1.0-1.01.0-1.0
Delta time to tail flick, test, before/after SA0.50.50.80.50.6-0.3-0.20.5-0.80.80.60.80.80.80.6-0.60.60.60.90.70.9-0.50.90.9-0.90.9
Tibia length0.61.63.21.51.8-1.31.61.3-1.41.51.31.21.11.40.7-0.7-0.10.61.3-0.11.4-1.41.31.31.60.8
Ambulatory time before self-admin0.00.10.90.10.1-0.20.50.2-0.10.20.10.2-0.00.1-0.20.20.2-0.30.10.30.2-0.20.20.2-0.90.2
Ambulatory time after self-admin0.20.32.00.70.7-0.41.40.3-0.30.50.30.2-0.30.2-0.50.5-0.4-0.70.2-0.40.3-0.00.20.30.5-0.1
Bone: tissue strength0.40.40.80.40.4-0.50.30.4-0.60.50.50.60.70.60.6-0.60.90.80.60.90.6-0.90.60.5-0.80.7
Total heroin consumption0.10.20.4-0.4-0.20.5-0.5-0.3-0.10.10.10.30.40.40.4-0.40.60.40.40.60.5-0.30.40.4-0.60.6
Bone: trabecular number1.52.54.41.51.5-1.61.51.5-1.61.51.31.52.01.72.1-2.11.42.11.51.41.5-1.81.41.30.01.4
Bone: trabecular spacing4.25.611.0-2.1-2.22.5-2.0-2.32.4-2.1-1.7-2.3-3.0-2.4-3.13.1-2.6-3.3-2.2-2.6-2.02.5-2.0-1.90.1-2.2
Bone: trabecular thickness0.10.10.6-0.3-0.10.3-0.6-0.40.1-0.2-0.8-0.10.2-0.10.2-0.20.20.2-0.10.2-0.20.0-0.2-0.3-0.5-0.1
Bone: trabecular tissue density0.50.81.50.0-0.30.5-0.2-0.50.7-0.6-0.4-0.9-1.1-0.9-1.21.2-1.2-1.0-0.9-1.2-0.91.0-0.9-0.91.2-1.1
Water consumed over 24 hours0.20.31.50.00.3-0.1-0.2-0.0-0.40.3-0.10.40.80.11.2-1.20.81.10.40.80.1-0.00.30.2-0.70.5
Number of responses in last shaping day0.10.10.50.60.4-0.30.70.2-0.20.20.10.1-0.1-0.0-0.10.1-0.1-0.10.1-0.2-0.00.20.00.00.2-0.1