Hub : Genes

Fkrp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Fkrp 0.16 0.13 5.6e-17 0.08 0.11 0.1 0.11 4.2e-12 4.3e-16 4.7e-15 7.4e-16
2 Adipose mRNA stability Fkrp 0.03 0.03 5.1e-03 0.01 0.01 0.02 0.02 1.5e-02 1.7e-02 2.4e-03 5.8e-03
3 Liver mRNA stability Fkrp 0.03 0.03 7.7e-04 0.03 0.02 0.01 0.02 6.1e-04 9.9e-04 9.4e-03 1.3e-03
4 NAcc mRNA stability Fkrp 0.04 0.03 1.8e-06 0.03 0.03 0.03 0.03 1.8e-05 5.7e-06 1.2e-05 1.9e-05
5 NAcc intron excision ratio chr1_86610552_86613321 0.02 0.02 1.8e-03 0.01 0.01 0 0.01 1.3e-02 7.6e-03 6.3e-02 2.4e-02
6 Adipose gene expression Fkrp 0.07 0.06 2.1e-08 0.07 0.07 0.06 0.07 3.9e-08 5.6e-08 1.1e-07 3.2e-08
7 Eye gene expression Fkrp 0.23 0.2 8.6e-03 0.06 0.13 0.12 0.11 3.9e-02 5.0e-03 8.0e-03 1.0e-02
8 NAcc intron excision ratio chr1_86596881_86613321 0.02 0.02 1.8e-03 0.01 0.01 0 0.01 1.5e-02 5.3e-03 6.3e-02 2.8e-02
9 Brain mRNA stability Fkrp 0.04 0.04 9.4e-04 0.03 0.02 0.02 0.02 2.1e-03 2.2e-03 5.6e-03 4.1e-03
10 Brain isoform ratio NM_001025678.1 0.03 0.03 3.8e-03 0.02 0.02 0.04 0.03 5.3e-03 2.7e-03 2.3e-04 1.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.10.60.40.20.20.2-0.20.3-0.20.20.8-0.6
Area under the delay curve0.50.81.7-1.3-1.1-1.0-0.90.9-0.90.9-0.90.30.0
BMI with tail1.13.85.12.32.22.02.0-2.01.9-2.02.0-1.90.5
BMI without tail1.05.36.42.42.52.42.4-2.42.3-2.42.4-2.50.9
Body weight2.08.511.43.43.43.03.1-3.03.0-3.03.0-2.60.7
Weight adjusted by age0.10.20.70.20.40.30.4-0.40.3-0.40.4-0.80.4
Bone surface0.50.91.61.31.11.01.0-1.01.1-1.01.0-0.2-0.2
Bone volume0.20.50.80.90.80.70.7-0.70.8-0.70.70.2-0.4
Breakpoint value in progressive ratio session1.83.25.6-2.4-1.9-2.0-1.91.9-1.91.9-1.90.7-0.2
Number of licking bursts1.33.95.12.22.32.02.1-2.02.0-2.12.0-1.90.4
Context. condit. distance diff. score0.00.00.10.40.20.10.2-0.20.2-0.20.20.1-0.0
Locomotion velocity, session 10.40.41.0-0.5-0.7-0.5-0.50.5-0.70.5-0.51.0-0.6
Locomotion distance, session 10.00.00.2-0.1-0.1-0.2-0.10.1-0.10.1-0.10.4-0.2
Locomotion velocity, session 21.62.02.61.61.61.51.5-1.51.5-1.51.5-1.10.2
Locomotion distance, session 20.40.60.80.80.90.70.8-0.80.8-0.80.8-0.90.4
Locomotion velocity, session 30.30.30.60.80.50.50.6-0.60.6-0.60.6-0.30.0
Locomotion distance, session 30.80.91.5-1.2-1.2-1.0-1.00.9-0.90.9-0.90.7-0.1
Stereotopy head waving bouts, day 30.70.91.61.31.10.91.0-1.00.9-1.01.0-0.6-0.0
Stereotopy head waving duration, day 30.60.71.51.21.00.80.8-0.80.8-0.80.8-0.4-0.1
Locomotion velocity, session 70.70.81.5-0.5-0.9-0.9-0.90.9-0.80.9-0.91.2-0.7
Locomotion distance, session 70.10.10.30.60.10.00.1-0.10.3-0.10.10.3-0.2
Stereotopy head waving bouts, day 70.40.50.70.50.70.90.8-0.80.6-0.80.8-0.60.1
Stereotopy head waving duration, day 70.40.50.70.50.70.80.8-0.80.7-0.80.8-0.60.2
Locomotion velocity, session 80.00.00.20.0-0.2-0.2-0.20.2-0.10.2-0.20.4-0.3
Locomotion distance, session 80.00.00.00.20.20.00.1-0.10.2-0.10.1-0.10.1
Degree of sensitization distance0.80.82.21.51.10.80.9-0.90.9-0.90.9-0.4-0.1
Degree of sensitization stereotypy0.50.60.90.50.71.00.9-0.90.8-0.90.9-0.80.3
Conditioned locomotion0.20.20.6-0.8-0.4-0.4-0.40.4-0.30.4-0.4-0.50.5
Cocaine response after cond. corrected0.20.40.50.60.60.60.6-0.60.7-0.60.6-0.70.2
Cocaine response after cond. not corrected0.81.21.51.11.21.11.1-1.11.1-1.11.1-1.20.5
Cocaine response before conditioning1.92.33.51.91.81.61.6-1.61.5-1.61.6-1.40.5
Saline control response1.21.62.21.51.41.31.4-1.41.4-1.41.4-1.10.3
Bone: connectivity density0.00.10.10.30.30.30.2-0.20.3-0.20.20.3-0.3
Bone: cortical apparent density0.00.10.1-0.2-0.4-0.2-0.30.3-0.20.3-0.30.30.1
Bone: cortical area1.62.64.22.01.91.71.7-1.71.7-1.71.7-0.90.0
Bone: cortical porosity0.10.10.1-0.2-0.1-0.4-0.30.4-0.30.3-0.40.0-0.1
Bone: cortical porosity0.00.00.20.20.30.10.1-0.10.1-0.10.1-0.40.1
Bone: cortical thickness0.50.81.41.21.10.90.9-0.91.0-0.90.9-0.1-0.2
Bone: cortical thickness0.81.01.51.21.11.01.1-1.11.1-1.11.1-0.3-0.0
Bone: cortical tissue density0.10.10.2-0.3-0.5-0.3-0.40.4-0.30.4-0.40.40.0
Condit. Reinf. active minus inactive responses0.81.01.11.01.01.01.0-1.00.9-1.01.0-1.10.3
Condit. Reinf. active-inactive response ratio0.90.91.70.91.01.01.0-1.00.8-1.01.0-1.30.5
Condit. Reinf. active responses0.50.60.80.90.80.80.8-0.80.7-0.80.8-0.80.2
Condit. Reinf. inactive responses0.10.10.50.0-0.3-0.2-0.30.3-0.20.3-0.30.7-0.4
Incentive salience index mean0.70.91.11.11.01.01.0-1.00.9-1.01.0-0.90.2
Condit. Reinf. lever presses0.20.30.50.70.60.70.6-0.60.6-0.60.6-0.40.0
Condit. Reinf. active minus inactive responses0.00.00.10.30.10.20.1-0.10.1-0.10.10.2-0.2
Condit. Reinf. active-inactive response ratio0.00.10.10.40.20.30.2-0.20.3-0.20.20.3-0.3
Condit. Reinf. active responses0.10.10.1-0.2-0.3-0.3-0.30.3-0.30.3-0.30.4-0.1
Condit. Reinf. inactive responses0.30.40.6-0.7-0.7-0.7-0.70.7-0.80.7-0.70.5-0.0
Condit. Reinf. lever presses0.10.20.50.40.50.40.4-0.40.4-0.40.4-0.70.4
Condit. Reinf. lever reinforcers received0.10.10.1-0.3-0.4-0.3-0.30.3-0.30.3-0.30.4-0.1
Conditioned reinforcement - actives1.03.95.92.42.32.02.0-2.02.0-2.02.0-1.80.4
Conditioned reinforcement - inactives1.12.95.02.22.01.81.8-1.81.8-1.81.8-1.20.1
Conditioned locomotion1.31.93.31.81.71.31.5-1.41.5-1.41.4-1.00.0
Patch foraging indifference point 0 sec0.10.40.70.80.70.70.7-0.70.6-0.70.7-0.3-0.2
Patch foraging indifference point AUC2.45.89.03.02.62.52.5-2.52.6-2.52.5-2.00.6
Delay disc. indifference point, 0s delay0.40.40.5-0.7-0.6-0.7-0.60.6-0.50.6-0.60.7-0.6
Delay disc. indifference point, 16s delay0.20.30.5-0.6-0.7-0.6-0.50.5-0.60.5-0.5-0.1-0.0
Delay disc. indifference point, 2s delay1.51.62.7-1.6-1.6-1.4-1.31.3-1.31.3-1.30.7-0.0
Delay disc. indifference point, 24s delay0.10.10.6-0.2-0.10.10.1-0.1-0.1-0.10.1-0.80.5
Delay disc. indifference point, 4s delay0.10.10.20.10.30.30.4-0.50.5-0.40.4-0.30.2
Delay disc. indifference point, 8s delay0.91.53.2-1.8-1.5-1.3-1.31.3-1.21.3-1.20.5-0.2
Indifference point function ln k1.13.24.3-2.1-2.0-1.9-1.81.8-1.81.8-1.81.9-0.5
Indifference point function log k1.13.24.3-2.1-2.0-1.9-1.81.8-1.81.8-1.81.9-0.5
Patch foraging total patch changes 0 sec0.20.50.70.80.80.80.8-0.80.7-0.80.8-0.3-0.2
Patch foraging total patch changes 12 sec2.23.05.52.31.91.81.8-1.81.8-1.81.8-1.30.2
Patch foraging total patch changes 18 sec1.22.84.82.21.81.81.8-1.81.7-1.81.8-1.10.1
Patch foraging total patch changes 24 sec0.51.72.31.51.51.31.3-1.31.3-1.31.3-1.20.1
Patch foraging total patch changes 6 sec2.03.45.62.42.01.91.9-1.91.9-1.91.9-1.30.3
Patch foraging time to switch 0 sec0.83.24.3-2.1-1.9-1.9-1.91.9-1.91.9-1.91.3-0.4
Patch foraging water rate 0 sec1.03.95.12.32.22.12.1-2.12.1-2.12.1-1.30.3
Patch foraging water rate 12 sec0.00.10.10.20.40.20.3-0.30.3-0.20.20.1-0.3
Patch foraging water rate 18 sec0.00.00.10.00.20.10.2-0.20.2-0.20.20.2-0.2
Patch foraging water rate 24 sec0.00.00.2-0.20.10.10.1-0.10.1-0.10.10.4-0.5
Patch foraging water rate 6 sec0.71.01.90.81.11.01.0-1.01.0-1.01.0-1.40.5
Seeking ratio, delayed vs. immediate footshock1.92.73.7-1.9-1.9-1.6-1.61.6-1.71.6-1.61.8-0.7
Distance traveled before self-admin0.00.00.1-0.1-0.1-0.1-0.0-0.0-0.0-0.00.0-0.20.1
Distance traveled after self-admin0.50.91.7-1.3-1.1-1.1-1.01.0-0.91.0-1.00.40.1
Extensor digitorum longus weight2.08.010.63.23.33.13.0-3.03.1-3.03.0-2.00.6
Bone: elastic displacement0.81.01.9-0.8-1.0-0.9-1.01.0-1.01.0-1.01.4-0.8
Bone: elastic work0.20.20.50.70.40.40.4-0.30.3-0.30.30.4-0.7
Bone: endosteal estimation0.00.00.00.1-0.10.00.00.00.0-0.0-0.0-0.0-0.1
Bone: endosteal perimeter0.10.10.20.50.40.30.4-0.40.3-0.40.4-0.2-0.2
Epididymis fat weight0.10.41.5-0.4-0.6-0.5-0.50.5-0.60.6-0.51.2-0.7
Delta time in closed arm before/after self-admin0.60.61.5-0.8-0.8-0.7-0.70.7-0.70.7-0.71.2-0.4
Delta time in open arm before/after self-admin0.20.30.70.30.50.50.5-0.50.5-0.50.5-0.80.4
Diff in mean of infusions in LGA sessions1.42.64.4-2.1-1.9-1.7-1.71.7-1.71.7-1.60.9-0.3
Delay discount exponential model param0.40.61.31.11.00.80.7-0.70.7-0.70.7-0.1-0.1
Extinction: sum of active levers before priming0.00.00.1-0.2-0.0-0.1-0.10.1-0.20.1-0.10.00.0
Active lever presses in extinction session 60.50.52.10.10.50.50.6-0.60.5-0.70.7-1.40.9
Bone: final force0.60.91.31.01.21.01.0-1.01.0-1.01.0-0.80.2
Bone: final moment0.81.41.91.31.41.21.2-1.31.2-1.21.2-0.80.1
Food consumed during 24 hour testing period3.26.37.8-2.8-2.7-2.7-2.62.6-2.72.6-2.62.4-0.9
Glucose0.71.22.1-1.0-1.2-1.0-1.11.1-0.91.1-1.11.4-0.8
Heart weight1.21.92.91.71.61.41.4-1.41.4-1.41.4-1.30.2
Delay discount hyperbolic model param0.30.41.11.00.90.70.6-0.60.6-0.60.6-0.1-0.1
Intermittent access intake day 1-15 change0.00.20.40.70.40.60.5-0.50.3-0.50.5-0.1-0.3
Intermittent access intake escalation0.10.40.70.80.60.80.7-0.70.5-0.70.7-0.3-0.2
Intermittent access intake escalation 20.10.10.2-0.2-0.4-0.2-0.20.2-0.30.2-0.20.5-0.3
Intermitt. access day 1 inactive lever presses0.00.61.51.00.70.70.7-0.70.6-0.80.7-1.20.5
Intermitt. access day 15 inactive lever presses0.10.50.90.80.60.60.7-0.70.4-0.70.7-1.00.4
Intermitt. access escalation Index0.10.41.0-0.8-0.9-0.7-0.60.6-1.00.6-0.6-0.00.1
Intermittent access day 1 total infusions1.33.95.72.42.42.12.1-2.02.2-2.02.0-1.4-0.1
Intermittent access day 15 total infusions0.71.72.71.61.51.51.4-1.41.3-1.31.3-0.7-0.4
Intermittent access terminal intake (last 3 days)0.81.42.31.51.41.31.2-1.21.3-1.21.2-0.5-0.4
Intermittent access total infusions2.42.94.32.02.11.91.8-1.81.8-1.71.8-1.1-0.2
Intermittent access day 1 locomotion0.50.92.01.41.30.91.0-0.91.0-0.90.9-0.3-0.4
Intermittent access day 15 total locomotion0.10.40.70.80.80.60.6-0.60.6-0.50.60.2-0.8
Intermittent access total locomotion1.72.13.71.91.81.51.5-1.51.5-1.51.5-0.5-0.5
Intermittent access standard deviation0.10.30.5-0.7-0.6-0.5-0.60.6-0.60.6-0.60.6-0.5
Left kidney weight3.124.933.35.85.85.25.2-5.25.3-5.25.2-4.21.4
Right kidney weight3.121.327.95.35.34.94.9-4.94.9-4.94.9-3.81.2
Cocaine induced anxiety0.00.00.2-0.1-0.0-0.2-0.20.20.20.2-0.20.4-0.0
Post-drug Anxiety0.10.10.1-0.3-0.2-0.3-0.30.3-0.10.3-0.30.4-0.1
Baseline Anxiety0.50.91.4-1.0-1.1-0.9-0.91.0-1.20.9-0.90.8-0.5
Tail length0.73.95.12.22.32.12.0-2.02.1-2.02.0-2.00.8
Length with tail0.73.14.22.02.11.91.8-1.81.9-1.81.8-1.40.4
Length without tail0.31.32.21.51.41.21.2-1.21.2-1.21.2-0.6-0.1
Times rat made contact with spout0.30.40.8-0.5-0.7-0.6-0.60.6-0.60.6-0.60.9-0.5
Lifetime Intake2.83.45.02.22.22.01.9-1.92.0-1.91.9-1.4-0.2
Liver weight, left2.74.66.42.02.32.12.2-2.22.1-2.22.2-2.51.3
Liver weight, right1.93.44.11.82.01.91.9-1.91.9-1.91.9-2.00.6
Locomotor activity1.72.73.51.71.91.71.7-1.71.6-1.71.7-1.70.5
Locomotor testing distance0.92.33.11.51.81.51.6-1.61.4-1.61.6-1.60.4
Locomotor testing rearing2.59.311.73.43.43.13.2-3.23.0-3.23.2-3.10.9
Locomotion in novel chamber0.91.21.6-1.1-1.3-1.1-1.11.1-1.21.1-1.11.2-0.4
Locomotion in novel chamber post-restriction0.51.42.3-1.5-1.4-1.2-1.21.2-1.31.2-1.20.9-0.1
Fecal boli incidents, locomotor time 10.10.30.60.80.60.50.6-0.60.4-0.60.60.4-0.5
Change in fecal boli incidents, locomotor task0.60.71.1-0.7-1.1-0.7-0.90.9-0.90.9-0.90.5-0.3
Time >=10cm from walls, locomotor time 10.00.00.1-0.1-0.1-0.3-0.00.0-0.2-0.0-0.0-0.1-0.1
Bouts of movement, locomotor time 12.63.34.7-2.0-2.2-1.9-2.02.0-2.02.0-2.01.1-0.6
Total resting periods, locomotor time 13.43.95.4-2.1-2.3-2.1-2.12.1-2.12.1-2.11.5-0.7
Rest time, locomotor task time 10.20.30.7-0.1-0.5-0.6-0.50.4-0.50.4-0.50.8-0.7
Distance moved, locomotor task time 10.30.91.90.41.01.00.9-0.90.9-0.90.9-1.41.0
Vertical activity count, locomotor time 10.00.30.70.30.40.70.4-0.40.3-0.40.4-0.80.7
Time >=10cm from walls, locomotor time 20.00.00.10.30.10.10.1-0.10.1-0.10.10.3-0.1
Bouts of movement, locomotor time 22.06.811.1-3.3-2.8-2.7-2.82.8-2.82.8-2.81.4-0.8
Total resting periods, locomotor time 21.66.610.3-3.2-2.8-2.7-2.72.7-2.82.7-2.71.6-1.0
Rest time, locomotor task time 20.40.61.7-0.4-0.7-0.9-0.70.7-0.60.7-0.71.3-0.8
Distance moved, locomotor task time 21.01.32.31.01.21.41.1-1.11.2-1.11.1-1.50.9
Vertical activity count, locomotor time 20.10.30.90.40.30.80.3-0.30.3-0.30.3-0.90.8
Light reinforcement 10.10.31.00.40.60.40.5-0.50.3-0.60.5-1.00.4
Light reinforcement 20.51.12.21.11.21.01.0-1.01.0-1.01.0-1.50.7
Bone: marrow area0.00.00.00.1-0.00.10.1-0.10.1-0.10.1-0.10.0
Bone: maximum diameter2.34.66.12.42.52.22.2-2.22.2-2.22.2-2.20.7
Bone: maximum force0.30.50.80.80.90.80.8-0.80.8-0.80.8-0.4-0.0
Bone: maximum moment0.40.81.21.11.10.90.9-0.91.0-0.90.9-0.3-0.1
Mean time between licks in bursts0.00.00.1-0.10.0-0.0-0.00.0-0.00.0-0.0-0.40.2
Mean num. licks in bursts2.15.87.5-2.6-2.7-2.5-2.52.5-2.52.5-2.52.5-0.7
Cd content in liver0.40.41.0-0.4-0.6-0.7-0.60.6-0.70.6-0.61.0-0.4
Co content in liver1.01.11.7-1.3-1.2-1.1-1.11.1-1.21.1-1.10.9-0.3
Cu content in liver0.50.50.80.70.80.80.7-0.70.9-0.70.7-0.80.5
Fe content in liver3.13.95.02.22.22.12.1-2.02.0-2.02.0-1.80.6
K content in liver0.30.30.60.30.50.60.6-0.60.6-0.60.6-0.80.4
Mg content in liver0.80.92.20.61.00.80.9-0.90.9-0.90.9-1.50.9
Mn content in liver0.91.01.41.01.01.11.0-1.01.2-1.01.0-0.90.5
Na content in liver0.00.00.1-0.3-0.20.0-0.10.00.10.1-0.00.10.2
Rb content in liver0.00.00.1-0.10.10.00.2-0.20.2-0.20.2-0.40.4
Se content in liver5.26.211.12.12.52.52.5-2.52.4-2.52.5-3.31.7
Sr content in liver0.10.10.20.50.40.30.3-0.30.3-0.30.3-0.1-0.3
Zn content in liver1.92.33.91.21.61.51.6-1.51.5-1.61.6-2.00.9
Bone: minimum diameter0.30.60.90.90.80.80.8-0.80.9-0.80.8-0.1-0.2
Time in familiar zone, hab. session 10.20.20.60.80.60.30.4-0.30.3-0.30.30.3-0.5
Time in novel zone, hab. session 10.70.81.50.70.80.90.9-0.80.9-0.90.8-1.20.7
Total zone transitions, hab. session 10.00.00.10.30.20.10.2-0.20.1-0.20.20.2-0.2
Total locomotion distance, hab. session 10.40.50.7-0.7-0.7-0.8-0.70.7-0.70.7-0.70.8-0.4
Locomotion velocity, hab. session 11.11.51.9-1.2-1.4-1.4-1.31.3-1.31.3-1.31.3-0.5
Time in familiar zone, hab. session 20.40.51.11.10.80.70.7-0.70.6-0.70.70.1-0.5
Time in novel zone, hab. session 20.40.51.3-1.1-0.7-0.7-0.60.6-0.60.6-0.6-0.40.5
Total zone transitions, hab. session 20.30.40.60.80.80.70.7-0.70.6-0.70.7-0.40.0
Total locomotion distance, hab. session 20.50.60.9-0.9-0.9-0.8-0.80.8-0.90.8-0.80.9-0.4
Locomotion velocity, hab. session 20.30.30.5-0.6-0.6-0.7-0.60.6-0.60.6-0.60.7-0.3
Novel to familiar place preference ratio0.50.61.00.70.80.80.8-0.80.8-0.80.8-1.00.5
Novelty place preference0.40.50.80.70.70.70.7-0.70.7-0.70.7-0.90.4
Time in novel zone, NPP test0.50.60.80.70.80.70.8-0.80.8-0.80.8-0.90.4
Total zone transitions, NPP test0.10.10.30.40.50.30.4-0.40.3-0.40.4-0.2-0.0
Total locomotion distance, NPP test0.00.00.10.30.20.10.2-0.20.1-0.20.2-0.0-0.1
Locomotion velocity, NPP test0.00.00.10.30.30.10.2-0.20.1-0.20.2-0.0-0.2
Intraocular pressure0.10.10.7-0.1-0.3-0.3-0.30.3-0.30.3-0.30.8-0.3
Delta distance traveled before/after self-admin0.80.91.6-1.3-1.1-1.0-1.01.0-0.91.0-1.00.50.0
Delta ambulatory time before/after self-admin0.10.20.3-0.6-0.5-0.4-0.50.5-0.40.5-0.50.50.1
Parametrial fat weight0.00.10.20.40.00.30.2-0.20.3-0.20.20.4-0.0
Pavlov. Cond. lever latency0.50.71.0-0.6-0.8-0.9-0.90.9-0.70.9-0.91.0-0.4
Pavlov. Cond. magazine entry latency0.30.40.90.30.60.60.6-0.60.5-0.60.6-1.00.6
Pavlov. Cond. change in total contacts0.40.41.0-1.0-0.7-0.6-0.60.6-0.80.6-0.60.10.1
Pavlov. Cond. index score0.40.51.30.40.70.70.7-0.70.6-0.70.7-1.10.6
Pavlov. Cond. latency score0.20.20.60.10.40.40.4-0.40.2-0.40.4-0.80.4
Pavlov. Cond. lever contacts0.40.40.80.50.70.70.7-0.70.5-0.70.7-0.90.3
Pavlov. Cond. magazine entry number0.20.20.6-0.1-0.4-0.4-0.40.4-0.30.4-0.40.8-0.6
Pavlov. Cond. intertrial magazine entries0.00.00.10.20.10.00.0-0.00.1-0.00.00.3-0.4
Pavlov. Cond. lever-magazine prob. diff.0.50.61.30.50.80.80.8-0.80.6-0.80.8-1.10.6
Pavlov. Cond. response bias1.21.52.31.11.31.31.3-1.31.1-1.31.3-1.50.7
Pavlov. Cond. lever latency0.10.10.2-0.5-0.4-0.4-0.40.4-0.30.4-0.40.3-0.2
Pavlov. Cond. magazine entry latency0.00.00.10.00.10.00.0-0.0-0.0-0.00.0-0.30.1
Pavlov. Cond. change in total contacts0.20.40.6-0.7-0.7-0.6-0.60.6-0.60.6-0.60.8-0.3
Pavlov. Cond. index score0.00.00.0-0.1-0.0-0.1-0.00.0-0.10.0-0.0-0.20.1
Pavlov. Cond. latency score0.00.00.0-0.2-0.1-0.2-0.20.2-0.20.2-0.20.00.0
Pavlov. Cond. lever contacts0.20.30.50.70.70.60.6-0.60.6-0.60.6-0.60.2
Pavlov. Cond. magazine entry number0.20.30.40.50.50.60.6-0.60.6-0.60.6-0.30.2
Pavlov. Cond. intertrial magazine entries0.00.00.10.20.00.10.1-0.10.1-0.10.10.3-0.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.10.20.10.1-0.10.0-0.10.1-0.30.1
Pavlov. Cond. response bias0.00.00.10.20.20.10.2-0.20.1-0.20.2-0.30.1
Time in closed arm before self-admin0.40.71.41.21.00.90.9-0.90.8-0.90.9-0.4-0.0
Time in closed arm after self-admin1.51.72.0-1.4-1.4-1.3-1.31.3-1.31.3-1.31.4-0.5
Time in open arm before self-admin0.30.40.7-0.9-0.7-0.7-0.60.6-0.70.6-0.60.4-0.3
Time in open arm after self-admin0.00.00.2-0.00.20.10.1-0.10.2-0.10.1-0.40.2
Bone: periosteal estimation0.30.81.21.11.00.90.9-0.91.0-0.90.9-0.60.1
Bone: periosteal perimeter0.51.11.91.41.21.01.1-1.11.0-1.11.1-0.5-0.1
Bone: post-yield work0.20.30.4-0.6-0.6-0.7-0.70.6-0.50.7-0.60.5-0.2
Progressive ratio test 1 active lever presses2.64.57.12.72.52.42.2-2.22.3-2.12.2-1.4-0.3
Progressive ratio test 1 breakpoint2.44.16.42.52.42.32.1-2.12.2-2.02.1-1.3-0.4
Progressive ratio test 1 inactive lever presses1.33.55.02.22.22.11.9-1.91.9-1.91.9-1.60.0
Progressive ratio test 2 active lever presses3.24.56.82.62.52.32.2-2.22.1-2.22.2-1.7-0.1
Progressive ratio test 2 breakpoint3.84.87.32.72.62.32.3-2.32.1-2.32.3-1.8-0.0
Progressive ratio test 2 inactive lever presses0.82.44.22.01.71.71.7-1.71.5-1.61.6-1.10.1
Incentive Sensitization - Responses1.02.84.42.12.01.71.8-1.81.5-1.81.8-1.30.1
Incentive Sensitization - Breakpoint1.22.64.32.11.91.71.7-1.71.5-1.71.7-1.30.1
Sum of active levers in priming session hrs 5-60.90.91.7-1.3-1.1-1.1-1.01.0-1.00.9-0.90.40.2
Progressive ratio0.61.73.4-1.9-1.5-1.4-1.41.3-1.41.3-1.30.5-0.2
Food seeking constrained by brief footshock3.24.05.4-2.3-2.3-2.1-2.01.9-2.22.0-1.92.1-0.8
Seeking ratio, punishment vs. effort0.10.20.9-0.1-0.4-0.3-0.30.3-0.30.3-0.31.0-0.4
Retroperitoneal fat weight0.00.10.20.30.20.50.2-0.20.3-0.20.20.5-0.2
Reaction time number correct1.13.85.12.02.32.02.0-2.02.1-2.02.0-1.70.9
Reaction time mean minus median0.21.31.8-1.1-1.3-1.1-1.21.2-1.21.2-1.21.2-0.3
Reaction time mean minus median AUC0.00.20.4-0.3-0.5-0.4-0.50.5-0.40.5-0.50.6-0.1
Reaction time num false alarms4.17.09.32.83.02.82.8-2.82.8-2.82.8-2.50.7
Reaction time num false alarms AUC2.86.48.32.72.92.72.7-2.62.7-2.62.6-2.30.6
Reaction time trials correct on left1.13.85.12.02.32.02.0-2.02.1-2.02.0-1.70.9
Reaction time trials on left1.13.85.32.02.32.02.0-2.02.1-2.02.0-1.80.9
Reaction time mean1.12.53.4-1.7-1.9-1.6-1.71.7-1.61.7-1.71.3-0.3
Reaction time mean AUC0.82.02.7-1.6-1.6-1.4-1.51.5-1.41.5-1.51.2-0.2
Median of all reaction times1.32.02.8-1.7-1.7-1.4-1.51.5-1.51.5-1.51.0-0.2
Reaction time omissions0.10.10.40.10.40.30.2-0.20.3-0.20.3-0.60.3
Reaction time false alarm rate0.60.91.21.01.11.01.0-1.01.0-1.01.0-0.9-0.0
Reaction time premature initiation rate0.30.40.9-0.5-0.7-0.5-0.60.6-0.60.6-0.60.9-0.7
Reaction time premature initiations0.00.10.10.30.30.40.3-0.30.3-0.30.30.2-0.2
Std. dev. reaction times0.41.31.8-1.2-1.3-1.1-1.21.2-1.11.2-1.21.1-0.3
Reaction time trials completed1.13.85.32.02.32.02.0-2.02.1-2.02.0-1.80.9
Reaction time trials AUC1.45.06.82.42.62.32.3-2.32.4-2.32.3-2.01.0
Run reversals in cocaine runway, females0.40.50.7-0.6-0.5-0.7-0.80.8-0.60.8-0.80.6-0.2
Run reversals in cocaine runway, males0.30.30.50.70.50.50.6-0.60.5-0.60.6-0.30.2
Latency to leave start box in cocaine runway0.20.20.8-0.1-0.3-0.3-0.40.4-0.20.4-0.40.8-0.9
Latency to leave start box in cocaine runway, F0.10.20.50.60.40.30.2-0.20.4-0.20.20.4-0.7
Latency to leave start box in cocaine runway, M0.20.20.2-0.4-0.4-0.4-0.40.4-0.40.4-0.40.3-0.2
Std. dev. time between licks in bursts0.10.30.80.20.40.50.5-0.40.5-0.50.5-0.90.6
Total sessions with >9 infusions3.34.05.72.32.42.22.1-2.12.2-2.12.1-1.6-0.1
Short access day 1 total inactive lever presses1.73.45.02.22.11.91.9-1.91.8-1.91.9-1.50.2
Short access day 10 total inactive lever presses0.11.01.4-1.1-1.0-1.2-1.11.1-1.01.0-1.10.9-0.3
Short access day 1 total infusions1.42.84.12.02.01.81.7-1.71.8-1.71.7-1.2-0.1
Short access day 10 total infusions3.25.36.82.62.62.42.4-2.42.4-2.42.4-2.20.4
Short access total infusions2.53.64.92.12.22.12.0-1.92.0-1.91.9-1.70.1
Short access day 1 locomotion3.04.97.12.42.72.42.3-2.32.5-2.32.3-1.80.2
Short access day 10 total locomotion0.00.10.50.1-0.1-0.3-0.20.2-0.30.2-0.20.6-0.7
Short access total locomotion0.61.01.61.31.21.01.0-1.01.0-1.01.0-0.5-0.3
One hour access (0.3 mA shock)0.20.20.40.60.60.50.4-0.40.5-0.40.4-0.2-0.5
Compulsive drug intake0.10.10.20.40.20.20.2-0.20.1-0.20.2-0.40.4
One hour access (shock baseline)0.61.52.51.31.61.31.2-1.21.5-1.21.2-0.8-0.4
Social response proportion0.50.61.50.60.70.60.7-0.70.8-0.70.7-1.20.8
Social responses0.81.02.80.50.90.91.0-1.00.8-1.01.0-1.71.1
Social time2.23.46.3-2.5-2.2-1.9-1.91.9-2.01.9-1.91.00.1
Soleus weight0.20.61.00.71.00.80.8-0.80.7-0.80.8-0.90.4
Bone: stiffness0.71.41.81.21.31.21.2-1.21.3-1.21.2-1.10.4
Tibialis anterior weight3.813.117.24.04.13.83.8-3.83.9-3.83.8-3.01.0
Time to tail flick, vehicle, before self-admin1.41.72.51.61.41.51.3-1.31.6-1.31.3-0.70.4
Time to tail flick, vehicle, after self-admin0.20.40.5-0.7-0.7-0.7-0.60.6-0.70.6-0.60.6-0.5
Time to tail flick, test, before self-admin0.70.82.4-0.7-0.8-0.7-0.80.8-0.50.9-0.81.5-0.7
Time to tail flick, test, after self-admin0.10.10.50.50.30.0-0.00.00.10.0-0.00.7-0.7
Delta time to tail flick, vehicle, before/after SA0.40.40.6-0.6-0.7-0.7-0.60.6-0.70.6-0.60.7-0.4
Delta time to tail flick, test, before/after SA0.91.22.31.51.31.01.1-1.10.9-1.11.1-0.80.1
Tibia length0.51.33.01.21.41.01.1-1.11.0-1.11.1-1.70.6
Ambulatory time before self-admin0.00.10.2-0.4-0.4-0.4-0.20.2-0.30.2-0.2-0.10.1
Ambulatory time after self-admin0.81.42.3-1.5-1.3-1.3-1.31.2-1.21.2-1.20.60.1
Bone: tissue strength0.40.40.6-0.8-0.6-0.7-0.60.6-0.70.6-0.60.6-0.3
Total heroin consumption0.10.10.5-0.10.10.10.2-0.20.1-0.20.2-0.70.5
Bone: trabecular number0.00.10.40.20.10.10.0-0.00.10.00.00.6-0.6
Bone: trabecular spacing0.00.00.2-0.3-0.1-0.0-0.0-0.0-0.1-0.00.0-0.40.5
Bone: trabecular thickness1.11.52.91.71.41.31.3-1.31.3-1.31.3-0.4-0.3
Bone: trabecular tissue density0.10.20.50.50.40.30.3-0.30.3-0.40.3-0.70.4
Water consumed over 24 hours0.40.71.4-0.8-0.9-0.9-0.80.8-0.90.9-0.81.2-0.6
Number of responses in last shaping day1.52.02.81.71.71.31.4-1.41.4-1.41.4-1.60.3