Hub : Genes

Fhl2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Fhl2 0.03 0.03 3.4e-03 0.01 0.01 0.02 0.01 6.3e-02 1.2e-02 9.8e-04 2.8e-02
2 IC mRNA stability Fhl2 0.15 0.11 2.1e-03 0.04 0.04 0.03 0.03 1.1e-02 1.1e-02 1.4e-02 1.7e-02
3 Liver mRNA stability Fhl2 0.06 0.06 7.8e-03 0.01 0.01 0 0.01 1.1e-02 1.6e-02 1.5e-01 2.9e-02
4 Brain mRNA stability Fhl2 0.08 0.05 1.7e-04 0.03 0.04 0.04 0.04 9.3e-04 8.9e-05 1.5e-04 1.0e-04
5 PL mRNA stability Fhl2 0.31 0.11 0.0e+00 0.16 0.23 0.22 0.22 1.8e-17 9.3e-25 1.7e-23 1.7e-23
6 Adipose gene expression Fhl2 0.61 0.12 0.0e+00 0.4 0.47 0.48 0.47 1.8e-47 8.1e-58 1.4e-59 1.1e-58
7 BLA mRNA stability Fhl2 0.11 0.07 1.1e-03 0.05 0.07 0.05 0.06 1.0e-03 1.6e-04 1.3e-03 7.4e-04
8 PL isoform ratio NM_031677.2 0.05 0.05 6.5e-03 0.02 0.02 0.01 0.02 1.2e-03 3.5e-03 1.2e-02 2.6e-03
9 PL alternative TSS NM_031677.2 0.04 0.04 6.1e-03 0.01 0.02 0.02 0.02 1.4e-02 2.9e-03 6.3e-03 3.5e-03
10 OFC gene expression Fhl2 0.38 0.17 1.6e-03 0.1 0.12 0.06 0.09 2.3e-03 1.1e-03 1.5e-02 3.4e-03
11 NAcc mRNA stability Fhl2 0.12 0.07 5.2e-12 0.08 0.08 0.07 0.07 1.3e-11 1.2e-11 1.8e-10 2.4e-11
12 BLA gene expression Fhl2 0.08 0.06 2.5e-03 0.04 0.04 0.03 0.04 2.9e-03 4.8e-03 1.3e-02 5.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.11.86.2-0.4-2.5-2.1-0.7-0.7-0.40.21.52.2-0.60.8-1.4
Area under the delay curve2.22.63.90.5-0.2-0.8-1.5-1.51.9-1.8-2.0-1.91.9-1.92.0
BMI with tail0.10.31.80.20.71.30.70.3-0.30.0-0.4-0.40.2-0.10.4
BMI without tail0.72.22.81.6-0.9-0.8-1.5-1.51.7-1.7-1.6-1.21.7-1.61.6
Body weight0.10.51.81.3-0.9-0.3-0.7-0.90.6-0.8-0.4-0.00.7-0.60.5
Weight adjusted by age1.72.64.3-0.91.81.82.02.1-1.71.81.20.7-1.71.6-1.4
Bone surface0.30.52.9-1.7-0.9-0.7-0.3-0.4-0.2-0.10.80.7-0.10.1-0.3
Bone volume0.61.13.6-1.2-1.9-1.6-0.6-0.6-0.20.01.21.6-0.30.5-0.9
Breakpoint value in progressive ratio session1.21.43.92.0-1.5-1.1-1.5-1.41.3-1.2-0.6-0.21.0-1.00.7
Number of licking bursts0.40.61.0-0.8-0.3-0.7-1.0-0.81.0-0.9-0.4-0.70.8-0.90.8
Context. condit. distance diff. score0.50.61.90.0-1.0-0.60.10.0-0.60.51.21.4-0.60.8-0.9
Locomotion velocity, session 10.10.10.70.8-0.2-0.2-0.3-0.30.3-0.3-0.2-0.10.2-0.20.1
Locomotion distance, session 10.70.92.70.41.41.71.31.2-1.01.00.40.0-0.80.8-0.5
Locomotion velocity, session 21.11.34.7-1.12.22.11.21.2-0.50.6-0.0-1.0-0.30.10.4
Locomotion distance, session 20.60.82.9-0.71.71.70.80.7-0.20.1-0.5-1.10.1-0.20.7
Locomotion velocity, session 30.30.30.60.60.00.30.40.4-0.50.50.80.6-0.60.6-0.6
Locomotion distance, session 30.10.21.31.2-0.3-0.1-0.00.0-0.10.10.30.4-0.20.2-0.3
Stereotopy head waving bouts, day 30.20.20.8-0.4-0.7-0.9-0.5-0.60.3-0.4-0.20.10.3-0.30.2
Stereotopy head waving duration, day 30.20.30.7-0.3-0.5-0.9-0.7-0.60.6-0.5-0.4-0.30.5-0.50.4
Locomotion velocity, session 72.32.54.1-1.42.02.01.92.0-1.61.71.20.3-1.51.4-0.9
Locomotion distance, session 70.30.41.2-0.51.11.10.70.7-0.40.40.2-0.4-0.20.20.1
Stereotopy head waving bouts, day 70.10.10.20.2-0.4-0.3-0.0-0.0-0.10.10.30.5-0.20.2-0.3
Stereotopy head waving duration, day 70.50.71.30.0-0.00.30.70.7-0.90.91.21.0-1.01.0-1.0
Locomotion velocity, session 82.02.43.4-0.80.71.21.61.6-1.81.71.81.5-1.81.8-1.8
Locomotion distance, session 81.21.72.5-0.90.81.41.61.4-1.61.41.51.1-1.31.4-1.2
Degree of sensitization distance0.50.51.7-0.61.00.70.00.00.4-0.4-0.7-1.30.6-0.71.0
Degree of sensitization stereotypy0.20.20.60.0-0.20.10.40.3-0.50.50.60.8-0.60.6-0.6
Conditioned locomotion0.60.71.90.5-1.4-1.2-0.9-1.10.7-0.9-0.30.30.7-0.60.4
Cocaine response after cond. corrected1.31.62.50.3-0.2-0.5-1.2-1.21.5-1.5-1.4-1.51.6-1.61.6
Cocaine response after cond. not corrected0.60.71.10.3-0.0-0.1-0.7-0.80.9-1.0-0.9-1.01.0-1.11.0
Cocaine response before conditioning1.41.72.30.10.81.31.41.5-1.51.51.31.1-1.51.5-1.4
Saline control response1.01.42.6-1.61.01.01.41.2-1.31.21.10.7-1.11.1-1.0
Bone: connectivity density0.30.51.7-1.0-1.3-1.2-0.6-0.60.1-0.30.60.70.1-0.0-0.3
Bone: cortical apparent density3.14.29.4-1.02.83.12.62.6-2.12.21.30.2-1.81.7-1.2
Bone: cortical area0.30.41.4-1.2-0.00.40.60.4-0.70.50.90.7-0.50.6-0.6
Bone: cortical porosity0.20.20.8-0.3-0.9-0.9-0.4-0.3-0.00.00.60.7-0.20.2-0.4
Bone: cortical porosity0.40.51.2-0.3-1.0-0.9-0.2-0.1-0.40.31.11.1-0.50.6-0.8
Bone: cortical thickness0.40.72.4-1.6-0.00.30.60.5-0.80.61.10.9-0.70.7-0.8
Bone: cortical thickness0.10.10.5-0.6-0.00.10.40.2-0.40.30.70.5-0.30.3-0.3
Bone: cortical tissue density3.24.39.1-1.02.73.02.72.6-2.22.21.40.3-1.91.8-1.3
Condit. Reinf. active minus inactive responses1.01.12.00.8-0.3-0.7-1.0-1.01.2-1.2-1.4-1.11.2-1.21.2
Condit. Reinf. active-inactive response ratio1.01.01.41.2-0.5-0.9-1.0-1.01.1-1.1-1.2-0.81.1-1.00.9
Condit. Reinf. active responses0.30.40.60.4-0.0-0.2-0.5-0.50.6-0.6-0.8-0.70.7-0.70.7
Condit. Reinf. inactive responses0.10.20.80.30.80.90.40.4-0.20.20.0-0.4-0.00.00.2
Incentive salience index mean0.10.20.3-0.0-0.3-0.4-0.5-0.50.5-0.5-0.4-0.30.5-0.40.4
Condit. Reinf. lever presses0.40.51.2-0.6-0.30.00.50.4-0.70.71.11.1-0.80.8-0.9
Condit. Reinf. active minus inactive responses0.91.12.01.4-0.7-1.1-1.2-1.11.1-1.1-1.0-0.71.0-1.00.9
Condit. Reinf. active-inactive response ratio1.11.32.91.6-1.5-1.7-1.3-1.31.0-1.0-0.90.10.8-0.70.5
Condit. Reinf. active responses0.60.81.30.5-0.0-0.4-0.8-0.81.0-1.0-0.9-1.11.1-1.11.1
Condit. Reinf. inactive responses0.50.72.3-1.11.51.40.90.9-0.60.50.4-0.7-0.30.20.1
Condit. Reinf. lever presses0.20.30.50.2-0.4-0.7-0.7-0.60.6-0.5-0.2-0.40.5-0.50.4
Condit. Reinf. lever reinforcers received0.70.91.80.60.2-0.3-0.8-0.81.0-1.0-1.0-1.31.1-1.21.3
Conditioned reinforcement - actives0.50.95.92.4-0.20.4-0.6-0.50.7-0.7-0.8-0.70.7-0.70.8
Conditioned reinforcement - inactives0.91.38.02.80.21.30.90.8-0.80.90.70.8-0.80.9-0.6
Conditioned locomotion0.81.02.81.60.71.71.31.0-1.10.90.50.4-0.70.8-0.5
Patch foraging indifference point 0 sec0.81.53.2-1.81.01.11.41.4-1.41.31.20.6-1.21.2-1.0
Patch foraging indifference point AUC0.20.42.01.40.30.5-0.1-0.20.3-0.4-0.7-0.70.5-0.50.4
Delay disc. indifference point, 0s delay1.11.22.80.21.41.71.41.4-1.11.20.70.2-1.01.0-0.8
Delay disc. indifference point, 16s delay2.83.14.21.1-1.4-1.8-2.0-2.02.0-2.0-1.8-1.21.9-1.81.7
Delay disc. indifference point, 2s delay0.91.01.70.5-0.2-0.2-0.8-0.91.1-1.1-1.3-1.11.2-1.21.3
Delay disc. indifference point, 24s delay0.20.20.40.0-0.1-0.5-0.6-0.50.7-0.5-0.6-0.60.5-0.50.5
Delay disc. indifference point, 4s delay0.10.10.30.30.50.60.20.10.1-0.1-0.3-0.50.2-0.30.4
Delay disc. indifference point, 8s delay1.61.82.7-0.3-0.2-1.0-1.4-1.31.6-1.5-1.6-1.61.6-1.61.6
Indifference point function ln k0.40.72.9-1.71.61.00.40.7-0.00.2-0.1-1.1-0.0-0.10.5
Indifference point function log k0.40.72.9-1.71.61.00.40.7-0.00.2-0.1-1.1-0.0-0.10.5
Patch foraging total patch changes 0 sec0.50.92.8-1.70.90.91.11.0-1.00.90.80.3-0.70.7-0.5
Patch foraging total patch changes 12 sec1.01.32.60.2-0.20.61.10.8-1.41.11.61.5-1.21.2-1.4
Patch foraging total patch changes 18 sec0.10.20.4-0.40.60.40.20.0-0.0-0.2-0.6-0.60.3-0.30.3
Patch foraging total patch changes 24 sec0.61.01.80.40.41.01.31.0-1.31.10.90.9-1.01.1-1.1
Patch foraging total patch changes 6 sec0.30.50.8-0.70.40.40.90.8-0.90.80.60.5-0.70.7-0.7
Patch foraging time to switch 0 sec0.20.41.10.0-0.6-0.50.10.2-0.40.50.71.1-0.70.7-0.9
Patch foraging water rate 0 sec0.51.12.00.6-0.1-0.1-0.9-1.01.2-1.3-1.1-1.31.3-1.31.4
Patch foraging water rate 12 sec0.30.61.8-1.30.5-0.2-0.3-0.20.6-0.5-0.9-1.10.6-0.70.9
Patch foraging water rate 18 sec0.10.21.4-1.20.4-0.1-0.20.10.3-0.1-0.0-0.50.1-0.20.4
Patch foraging water rate 24 sec0.20.21.6-1.20.6-0.2-0.00.10.2-0.1-0.4-0.60.2-0.20.4
Patch foraging water rate 6 sec0.60.82.5-0.80.90.2-0.5-0.21.0-0.7-1.1-1.60.8-0.91.0
Seeking ratio, delayed vs. immediate footshock0.80.96.62.6-1.3-0.2-0.2-0.3-0.20.10.51.2-0.30.4-0.8
Distance traveled before self-admin0.30.41.70.0-1.3-0.7-0.4-0.4-0.10.00.61.0-0.20.3-0.6
Distance traveled after self-admin1.92.37.00.6-1.7-0.70.40.4-1.31.22.12.6-1.61.7-2.1
Extensor digitorum longus weight2.18.332.9-1.85.75.23.33.2-1.51.7-0.8-2.6-0.90.60.8
Bone: elastic displacement1.21.42.80.2-1.3-1.7-1.6-1.41.3-1.3-0.9-0.51.1-1.10.8
Bone: elastic work0.50.62.1-0.4-1.4-1.4-0.9-1.00.5-0.60.10.50.4-0.4-0.0
Bone: endosteal estimation0.10.20.30.1-0.5-0.4-0.5-0.50.4-0.5-0.2-0.10.5-0.40.4
Bone: endosteal perimeter0.10.10.20.5-0.4-0.3-0.4-0.50.4-0.4-0.2-0.10.4-0.40.3
Epididymis fat weight0.10.20.60.70.40.5-0.1-0.10.3-0.3-0.6-0.70.5-0.40.6
Delta time in closed arm before/after self-admin0.40.41.7-1.3-0.0-0.7-0.6-0.40.6-0.5-0.5-0.60.5-0.50.5
Delta time in open arm before/after self-admin0.30.33.1-1.8-0.2-0.7-0.1-0.2-0.1-0.00.20.2-0.00.1-0.1
Diff in mean of infusions in LGA sessions0.50.61.5-0.3-1.2-1.0-1.0-1.00.8-0.8-0.40.10.6-0.60.4
Delay discount exponential model param2.42.74.0-0.40.30.81.61.6-1.91.82.01.9-2.02.0-2.0
Extinction: sum of active levers before priming2.02.28.61.6-2.9-2.1-1.5-1.90.9-1.2-0.31.10.9-0.60.2
Active lever presses in extinction session 61.31.31.91.4-0.6-0.1-1.0-1.21.2-1.3-1.4-1.01.4-1.31.4
Bone: final force0.61.02.1-0.8-0.00.51.00.8-1.21.01.41.3-1.11.1-1.1
Bone: final moment0.50.81.7-0.80.00.50.90.7-1.10.81.31.0-0.90.9-0.9
Food consumed during 24 hour testing period0.20.31.21.10.30.5-0.1-0.20.4-0.4-0.4-0.70.5-0.50.7
Glucose0.81.21.70.6-1.0-1.3-1.3-1.31.3-1.2-1.1-0.61.2-1.11.0
Heart weight0.20.30.7-0.30.40.1-0.4-0.20.6-0.5-0.6-0.80.5-0.60.6
Delay discount hyperbolic model param2.22.43.8-0.30.20.71.41.4-1.81.71.91.9-1.91.9-1.9
Intermittent access intake day 1-15 change0.20.42.41.6-0.40.20.20.3-0.40.50.60.7-0.50.6-0.5
Intermittent access intake escalation0.20.41.31.1-0.20.30.30.5-0.50.70.80.8-0.70.7-0.7
Intermittent access intake escalation 20.20.32.11.5-0.7-0.4-0.5-0.20.2-0.00.20.4-0.10.1-0.1
Intermitt. access day 1 inactive lever presses0.10.41.71.3-1.2-0.4-0.1-0.4-0.10.00.51.1-0.10.3-0.3
Intermitt. access day 15 inactive lever presses0.51.01.4-1.10.70.71.21.1-1.11.20.90.8-1.11.1-0.9
Intermitt. access escalation Index0.20.30.7-0.80.80.30.50.7-0.50.60.4-0.0-0.50.4-0.5
Intermittent access day 1 total infusions3.86.116.14.0-1.9-1.3-2.4-2.62.5-2.6-2.5-1.42.6-2.42.3
Intermittent access day 15 total infusions1.11.612.33.5-0.9-0.2-1.0-0.90.9-0.8-0.8-0.40.8-0.70.8
Intermittent access terminal intake (last 3 days)1.92.516.84.1-1.2-0.2-1.2-1.31.2-1.2-1.2-0.61.2-1.11.2
Intermittent access total infusions2.42.812.73.6-1.2-0.6-1.5-1.51.6-1.5-1.5-0.91.5-1.41.5
Intermittent access day 1 locomotion1.01.26.62.6-0.50.3-0.7-0.90.9-1.0-1.2-0.71.0-1.01.0
Intermittent access day 15 total locomotion0.30.64.02.00.81.40.50.6-0.30.3-0.0-0.3-0.20.10.1
Intermittent access total locomotion0.50.64.82.20.30.9-0.1-0.10.2-0.3-0.6-0.60.4-0.40.5
Intermittent access standard deviation0.40.84.42.1-1.4-0.8-0.8-0.90.5-0.5-0.10.50.4-0.20.2
Left kidney weight0.10.41.41.0-0.50.10.10.2-0.40.41.20.9-0.60.6-0.8
Right kidney weight0.62.54.70.50.51.71.61.5-1.81.62.21.6-1.71.7-1.8
Cocaine induced anxiety1.31.85.4-2.31.40.91.51.5-1.41.41.00.5-1.31.2-1.1
Post-drug Anxiety1.31.42.9-1.71.11.01.51.3-1.41.20.90.6-1.11.1-0.9
Baseline Anxiety0.80.93.31.8-0.6-0.4-0.7-1.00.9-1.0-1.0-0.51.0-1.01.0
Tail length1.14.47.22.3-2.4-2.6-2.7-2.52.3-2.2-1.3-0.62.0-1.91.4
Length with tail0.41.84.81.8-2.2-1.9-1.6-1.61.1-1.2-0.10.50.9-0.80.3
Length without tail0.10.20.5-0.0-0.20.30.40.2-0.60.30.70.7-0.40.4-0.5
Times rat made contact with spout2.52.84.40.7-1.5-1.8-2.1-2.02.0-1.9-1.4-1.01.8-1.81.6
Lifetime Intake1.72.19.73.1-1.0-0.3-1.2-1.31.3-1.3-1.4-0.81.4-1.31.3
Liver weight, left1.32.23.4-0.2-1.3-1.2-1.8-1.91.7-1.8-1.0-1.01.8-1.71.5
Liver weight, right0.91.53.5-0.4-1.7-1.9-1.5-1.71.2-1.4-0.7-0.11.2-1.10.9
Locomotor activity0.10.20.50.7-0.6-0.5-0.6-0.50.4-0.4-0.4-0.00.3-0.30.2
Locomotor testing distance0.20.31.20.4-1.1-1.0-0.4-0.3-0.00.00.40.9-0.20.3-0.6
Locomotor testing rearing0.40.82.1-0.4-0.9-0.80.10.2-0.60.71.31.4-0.90.9-1.2
Locomotion in novel chamber1.01.35.5-0.32.12.31.00.8-0.10.1-0.7-1.40.3-0.31.0
Locomotion in novel chamber post-restriction0.30.52.90.71.01.70.80.5-0.30.2-0.1-0.50.00.00.4
Fecal boli incidents, locomotor time 10.50.83.5-1.90.70.1-0.2-0.40.6-0.7-0.8-1.20.8-0.90.9
Change in fecal boli incidents, locomotor task0.30.31.81.3-0.50.10.1-0.0-0.30.20.50.7-0.30.3-0.4
Time >=10cm from walls, locomotor time 11.41.55.8-2.32.41.41.01.2-0.20.5-0.4-1.4-0.2-0.00.4
Bouts of movement, locomotor time 13.03.48.8-1.01.50.4-0.6-0.81.5-1.7-2.6-3.02.1-2.22.5
Total resting periods, locomotor time 12.52.87.4-1.31.70.6-0.3-0.51.2-1.4-2.3-2.71.7-1.92.2
Rest time, locomotor task time 12.83.44.71.7-1.1-1.4-1.9-2.12.0-2.2-2.0-1.52.2-2.21.9
Distance moved, locomotor task time 10.10.10.4-0.40.70.40.20.5-0.10.40.1-0.3-0.30.3-0.1
Vertical activity count, locomotor time 10.61.43.0-1.70.20.10.81.1-1.11.31.21.2-1.41.4-1.4
Time >=10cm from walls, locomotor time 20.10.21.5-1.2-0.1-0.3-0.3-0.30.3-0.3-0.3-0.20.3-0.30.2
Bouts of movement, locomotor time 20.30.51.40.81.11.20.40.20.1-0.2-0.8-1.00.4-0.50.8
Total resting periods, locomotor time 20.30.51.81.30.91.20.40.20.0-0.1-0.7-0.80.3-0.30.7
Rest time, locomotor task time 20.10.20.90.9-0.4-0.6-0.4-0.40.3-0.3-0.3-0.10.3-0.30.1
Distance moved, locomotor task time 20.40.52.0-1.41.00.70.10.30.3-0.1-0.6-1.00.3-0.40.5
Vertical activity count, locomotor time 20.40.62.5-1.60.70.80.80.8-0.70.70.40.3-0.70.6-0.6
Light reinforcement 10.61.56.40.51.92.51.71.3-1.20.90.1-0.4-0.50.50.1
Light reinforcement 20.10.20.8-0.50.40.90.40.1-0.2-0.1-0.3-0.30.3-0.20.4
Bone: marrow area0.10.10.20.1-0.4-0.3-0.4-0.50.3-0.4-0.2-0.10.4-0.40.4
Bone: maximum diameter0.10.10.5-0.5-0.7-0.4-0.2-0.3-0.1-0.00.50.6-0.10.1-0.3
Bone: maximum force0.50.81.5-1.20.00.50.90.6-1.10.81.21.1-0.80.9-0.9
Bone: maximum moment0.30.61.5-1.20.10.50.80.5-0.90.71.10.8-0.60.7-0.7
Mean time between licks in bursts0.40.93.0-0.71.61.71.21.2-0.70.80.4-0.4-0.60.5-0.1
Mean num. licks in bursts0.10.21.31.1-0.2-0.0-0.1-0.20.1-0.3-0.5-0.20.3-0.20.3
Cd content in liver2.52.89.63.1-2.3-2.1-1.9-1.81.4-1.4-0.50.21.1-1.00.5
Co content in liver1.31.57.62.8-1.3-1.3-1.3-1.21.0-1.0-0.5-0.10.8-0.80.5
Cu content in liver0.10.20.70.9-0.6-0.5-0.4-0.40.3-0.30.00.10.3-0.20.1
Fe content in liver0.81.04.0-0.1-2.0-1.8-0.8-0.80.0-0.20.81.4-0.10.2-0.8
K content in liver1.21.16.0-2.51.41.21.11.0-0.70.70.2-0.3-0.50.5-0.1
Mg content in liver0.50.52.2-1.50.70.60.70.7-0.60.60.50.1-0.50.5-0.3
Mn content in liver0.80.91.6-0.41.00.91.31.2-1.11.10.30.5-1.01.0-0.8
Na content in liver1.31.44.3-2.1-0.4-0.30.60.6-1.01.01.71.4-1.11.2-1.3
Rb content in liver0.91.14.3-0.32.12.01.31.0-0.60.5-0.7-1.0-0.20.10.4
Se content in liver0.10.10.20.00.00.2-0.1-0.30.3-0.4-0.5-0.40.4-0.40.4
Sr content in liver0.50.40.90.9-0.0-0.4-0.7-0.50.7-0.7-0.6-0.80.7-0.80.7
Zn content in liver0.00.00.30.5-0.2-0.1-0.2-0.10.2-0.10.2-0.00.1-0.10.1
Bone: minimum diameter0.20.30.7-0.80.50.80.70.5-0.60.50.50.2-0.40.4-0.2
Time in familiar zone, hab. session 12.22.13.21.0-1.5-1.5-1.7-1.81.6-1.7-1.2-0.71.6-1.51.3
Time in novel zone, hab. session 10.00.00.20.3-0.3-0.4-0.3-0.10.20.0-0.00.2-0.10.1-0.2
Total zone transitions, hab. session 12.23.14.3-0.51.21.62.02.0-2.02.11.91.4-2.02.0-1.8
Total locomotion distance, hab. session 10.50.72.0-0.11.31.41.11.0-0.70.80.4-0.2-0.60.5-0.3
Locomotion velocity, hab. session 10.91.22.7-0.51.41.61.41.4-1.11.20.80.2-1.00.9-0.7
Time in familiar zone, hab. session 20.20.20.40.4-0.6-0.6-0.7-0.50.5-0.4-0.1-0.00.4-0.40.2
Time in novel zone, hab. session 20.00.00.0-0.0-0.1-0.10.1-0.0-0.10.1-0.00.2-0.00.1-0.1
Total zone transitions, hab. session 20.10.10.60.80.20.50.10.10.0-0.1-0.3-0.20.1-0.10.1
Total locomotion distance, hab. session 20.70.92.41.01.00.8-0.2-0.20.7-0.7-1.2-1.60.9-0.91.2
Locomotion velocity, hab. session 20.40.61.51.01.11.00.10.10.4-0.3-0.8-1.20.5-0.60.8
Novel to familiar place preference ratio2.52.83.8-1.0-1.1-1.5-1.9-1.91.8-2.0-1.5-1.31.9-1.91.7
Novelty place preference2.42.63.6-0.9-1.1-1.5-1.8-1.91.8-1.9-1.5-1.21.9-1.81.7
Time in novel zone, NPP test2.93.14.4-0.8-1.4-1.8-2.1-2.12.0-2.1-1.6-1.22.0-1.91.7
Total zone transitions, NPP test0.30.41.60.71.11.30.70.8-0.40.50.2-0.2-0.50.4-0.2
Total locomotion distance, NPP test0.30.41.40.31.21.00.30.40.10.0-0.4-1.00.2-0.30.5
Locomotion velocity, NPP test0.50.72.9-0.11.71.60.91.0-0.40.5-0.0-0.8-0.30.10.2
Intraocular pressure0.50.72.21.31.21.50.50.40.2-0.1-0.6-1.10.4-0.40.7
Delta distance traveled before/after self-admin0.60.61.00.40.10.30.70.8-0.80.91.00.9-1.01.0-1.0
Delta ambulatory time before/after self-admin0.50.60.80.70.20.50.80.8-0.80.90.80.8-0.90.9-0.9
Parametrial fat weight0.10.11.01.0-0.40.1-0.0-0.3-0.0-0.3-0.20.20.2-0.10.1
Pavlov. Cond. lever latency0.60.82.0-0.00.60.1-0.4-0.40.8-0.7-1.3-1.40.9-1.01.3
Pavlov. Cond. magazine entry latency0.10.10.3-0.3-0.5-0.5-0.2-0.30.1-0.1-0.30.20.1-0.0-0.1
Pavlov. Cond. change in total contacts0.10.10.20.0-0.2-0.2-0.3-0.50.4-0.5-0.4-0.20.4-0.40.4
Pavlov. Cond. index score0.10.20.7-0.2-0.8-0.7-0.3-0.40.1-0.10.20.6-0.00.1-0.3
Pavlov. Cond. latency score0.20.20.7-0.1-0.9-0.6-0.2-0.2-0.10.10.50.8-0.20.3-0.6
Pavlov. Cond. lever contacts0.40.51.2-0.1-0.4-0.00.40.3-0.60.61.01.1-0.80.8-1.0
Pavlov. Cond. magazine entry number0.20.20.80.10.90.90.40.4-0.10.10.0-0.5-0.0-0.10.3
Pavlov. Cond. intertrial magazine entries0.50.61.2-0.40.1-0.1-0.8-0.70.9-0.9-0.6-1.11.0-1.01.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.2-0.7-0.6-0.4-0.50.2-0.3-0.10.30.2-0.1-0.0
Pavlov. Cond. response bias0.10.10.5-0.5-0.7-0.6-0.2-0.3-0.0-0.10.10.6-0.00.1-0.3
Pavlov. Cond. lever latency0.10.10.3-0.40.20.2-0.1-0.20.3-0.4-0.5-0.50.4-0.40.5
Pavlov. Cond. magazine entry latency1.31.52.40.30.30.51.21.3-1.51.51.31.3-1.51.5-1.5
Pavlov. Cond. change in total contacts0.10.10.60.0-0.7-0.8-0.5-0.40.2-0.20.30.20.2-0.1-0.0
Pavlov. Cond. index score0.20.30.60.5-0.4-0.20.20.3-0.50.50.60.8-0.50.6-0.7
Pavlov. Cond. latency score0.20.30.40.5-0.10.00.40.4-0.60.60.60.6-0.60.6-0.7
Pavlov. Cond. lever contacts0.10.10.50.6-0.6-0.7-0.3-0.20.10.00.30.4-0.10.1-0.3
Pavlov. Cond. magazine entry number0.70.81.4-0.60.0-0.1-0.7-0.81.0-1.1-1.0-1.11.1-1.11.2
Pavlov. Cond. intertrial magazine entries0.71.02.70.71.31.20.10.00.6-0.5-1.3-1.60.8-0.91.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.3-0.2-0.10.30.4-0.50.50.60.7-0.60.6-0.7
Pavlov. Cond. response bias0.60.81.60.2-0.5-0.30.40.6-0.80.91.21.2-1.01.1-1.2
Time in closed arm before self-admin1.31.74.02.0-1.6-1.4-1.4-1.51.3-1.3-0.8-0.11.1-1.00.8
Time in closed arm after self-admin0.40.42.31.5-1.1-0.6-0.4-0.40.1-0.00.50.8-0.10.2-0.4
Time in open arm before self-admin0.30.41.80.01.11.30.60.7-0.30.3-0.2-0.6-0.10.10.1
Time in open arm after self-admin0.40.53.4-1.80.30.00.50.5-0.60.50.50.4-0.60.5-0.5
Bone: periosteal estimation0.10.10.4-0.5-0.6-0.2-0.0-0.2-0.20.00.60.6-0.10.2-0.3
Bone: periosteal perimeter0.20.40.8-0.3-0.9-0.7-0.7-0.80.6-0.7-0.10.00.6-0.50.4
Bone: post-yield work0.60.91.6-0.80.30.71.00.9-1.11.01.31.0-1.01.1-1.0
Progressive ratio test 1 active lever presses0.81.04.92.20.00.9-0.4-0.50.6-0.7-1.1-0.90.9-0.91.0
Progressive ratio test 1 breakpoint0.91.04.72.2-0.10.7-0.5-0.70.7-0.9-1.2-0.91.0-1.01.1
Progressive ratio test 1 inactive lever presses0.60.93.92.0-0.40.90.80.5-0.90.70.81.2-0.70.8-0.7
Progressive ratio test 2 active lever presses0.60.76.02.40.71.30.30.5-0.10.2-0.1-0.5-0.1-0.00.2
Progressive ratio test 2 breakpoint0.60.75.42.30.81.40.30.5-0.10.2-0.1-0.6-0.0-0.10.3
Progressive ratio test 2 inactive lever presses0.71.15.62.4-0.01.30.80.8-0.80.90.80.9-0.90.9-0.7
Incentive Sensitization - Responses0.40.51.0-0.30.90.70.61.0-0.60.90.80.2-0.90.7-0.6
Incentive Sensitization - Breakpoint0.50.71.3-0.11.00.80.81.1-0.71.00.90.2-1.00.8-0.7
Sum of active levers in priming session hrs 5-62.72.54.40.5-1.7-1.7-2.1-2.01.9-1.8-1.3-0.71.6-1.61.3
Progressive ratio0.81.33.40.41.10.3-0.4-0.41.0-1.0-1.8-1.81.2-1.31.6
Food seeking constrained by brief footshock0.10.10.40.10.70.10.30.4-0.20.3-0.5-0.2-0.20.2-0.1
Seeking ratio, punishment vs. effort0.50.81.6-0.5-0.4-0.00.60.6-0.90.91.11.3-1.01.0-1.2
Retroperitoneal fat weight0.10.52.21.00.61.51.00.6-0.90.50.20.1-0.30.4-0.2
Reaction time number correct0.20.41.9-0.41.41.10.80.8-0.50.4-0.2-0.6-0.20.10.3
Reaction time mean minus median0.20.51.20.6-1.1-1.0-1.1-0.80.7-0.6-0.10.10.4-0.40.0
Reaction time mean minus median AUC0.10.41.01.0-0.9-0.8-0.9-0.60.6-0.4-0.00.10.3-0.3-0.0
Reaction time num false alarms0.40.51.90.11.41.40.90.8-0.50.4-0.2-0.6-0.20.20.3
Reaction time num false alarms AUC0.60.92.9-0.31.71.71.21.1-0.70.70.0-0.6-0.40.40.2
Reaction time trials correct on left0.20.41.9-0.41.41.10.80.8-0.50.4-0.2-0.6-0.20.10.3
Reaction time trials on left0.20.41.7-0.41.31.00.80.7-0.40.3-0.2-0.6-0.10.00.3
Reaction time mean1.01.63.91.8-2.0-2.0-1.6-1.51.1-1.0-0.30.30.8-0.70.1
Reaction time mean AUC0.91.53.21.7-1.8-1.8-1.5-1.41.1-1.1-0.50.10.9-0.80.3
Median of all reaction times1.31.84.42.0-2.1-2.1-1.6-1.61.1-1.1-0.40.30.9-0.80.2
Reaction time omissions0.10.20.50.5-0.7-0.5-0.4-0.20.10.00.70.5-0.20.2-0.3
Reaction time false alarm rate0.30.31.2-0.10.91.10.80.7-0.50.50.2-0.1-0.40.4-0.1
Reaction time premature initiation rate0.10.10.3-0.3-0.4-0.40.10.0-0.20.20.20.5-0.30.4-0.3
Reaction time premature initiations0.00.10.3-0.60.2-0.00.40.3-0.40.30.10.2-0.30.3-0.2
Std. dev. reaction times0.30.61.81.0-1.2-1.3-1.1-0.80.7-0.50.20.30.2-0.2-0.2
Reaction time trials completed0.20.41.7-0.41.31.00.80.7-0.40.3-0.2-0.6-0.10.00.3
Reaction time trials AUC0.20.41.6-0.41.30.90.70.7-0.40.3-0.2-0.6-0.10.00.3
Run reversals in cocaine runway, females0.30.31.7-1.30.90.60.50.5-0.20.3-0.1-0.3-0.20.20.1
Run reversals in cocaine runway, males0.40.43.41.9-0.30.3-0.3-0.40.4-0.5-0.4-0.30.5-0.50.4
Latency to leave start box in cocaine runway2.12.44.0-1.31.22.01.91.7-1.81.61.40.9-1.51.5-1.2
Latency to leave start box in cocaine runway, F2.32.63.6-1.20.91.31.91.7-1.91.81.61.4-1.81.8-1.7
Latency to leave start box in cocaine runway, M1.00.94.8-0.71.52.21.10.9-0.60.50.3-0.5-0.30.30.1
Std. dev. time between licks in bursts0.30.41.7-1.30.70.4-0.0-0.10.4-0.4-0.4-1.00.5-0.60.8
Total sessions with >9 infusions0.20.30.60.7-0.10.7-0.1-0.40.2-0.5-0.8-0.50.6-0.60.6
Short access day 1 total inactive lever presses0.50.72.00.60.51.41.10.9-1.00.90.60.5-0.70.7-0.5
Short access day 10 total inactive lever presses0.20.41.10.3-0.4-0.10.40.3-0.60.60.91.0-0.70.8-0.8
Short access day 1 total infusions0.40.63.51.90.51.60.40.3-0.10.0-0.4-0.40.1-0.20.3
Short access day 10 total infusions4.15.39.83.1-1.1-0.7-2.1-2.22.3-2.4-2.7-2.02.6-2.52.5
Short access total infusions1.62.04.72.2-0.60.1-1.1-1.31.3-1.5-1.7-1.21.6-1.51.6
Short access day 1 locomotion0.30.42.2-0.01.01.50.90.7-0.60.4-0.1-0.3-0.20.20.0
Short access day 10 total locomotion0.10.20.70.8-0.20.2-0.4-0.40.4-0.4-0.5-0.40.5-0.40.4
Short access total locomotion0.30.41.8-0.31.11.30.70.6-0.40.3-0.3-0.5-0.0-0.00.2
One hour access (0.3 mA shock)5.46.211.23.3-2.1-1.4-2.7-2.82.7-2.8-2.3-1.42.7-2.52.4
Compulsive drug intake1.01.29.6-3.11.10.30.70.9-0.60.70.5-0.1-0.60.5-0.5
One hour access (shock baseline)3.14.816.44.0-1.9-1.0-2.2-2.32.2-2.2-1.9-1.02.1-2.02.0
Social response proportion0.60.74.22.1-1.1-0.5-0.7-0.80.6-0.6-0.50.30.4-0.30.2
Social responses0.71.02.81.1-1.7-1.4-1.2-1.20.8-0.8-0.50.40.7-0.50.4
Social time1.31.87.51.4-2.7-2.1-1.4-1.40.5-0.60.81.60.10.0-0.6
Soleus weight0.61.65.0-1.62.22.21.51.5-0.91.00.2-0.7-0.70.6-0.1
Bone: stiffness1.42.23.2-0.30.71.31.81.5-1.81.71.81.5-1.61.7-1.5
Tibialis anterior weight1.24.016.2-1.24.03.62.22.3-0.91.2-0.7-1.9-0.70.40.5
Time to tail flick, vehicle, before self-admin0.70.71.7-1.0-1.1-1.3-0.9-1.10.7-0.9-0.40.00.7-0.60.5
Time to tail flick, vehicle, after self-admin0.40.53.2-1.8-0.6-1.1-0.5-0.50.4-0.40.00.20.2-0.20.1
Time to tail flick, test, before self-admin1.21.25.50.82.41.70.71.1-0.00.3-0.7-1.70.0-0.20.6
Time to tail flick, test, after self-admin0.20.20.60.50.50.80.50.1-0.2-0.1-0.5-0.40.3-0.20.5
Delta time to tail flick, vehicle, before/after SA0.10.10.6-0.80.40.20.20.3-0.20.30.2-0.0-0.20.2-0.2
Delta time to tail flick, test, before/after SA0.50.52.9-0.2-1.7-1.0-0.3-0.9-0.1-0.40.21.10.3-0.0-0.1
Tibia length0.41.14.0-2.0-1.0-0.50.30.1-0.80.61.51.6-0.80.9-1.1
Ambulatory time before self-admin0.20.31.40.1-1.2-0.8-0.5-0.50.1-0.10.30.7-0.00.1-0.4
Ambulatory time after self-admin1.31.53.81.1-1.0-0.10.50.5-1.11.11.61.9-1.31.4-1.7
Bone: tissue strength0.00.00.3-0.50.30.30.20.1-0.10.10.1-0.1-0.00.00.1
Total heroin consumption4.65.47.82.0-2.1-2.0-2.6-2.82.6-2.7-2.2-1.32.6-2.42.2
Bone: trabecular number1.11.95.4-0.5-2.3-1.9-0.4-0.4-0.70.51.72.3-0.91.0-1.6
Bone: trabecular spacing0.60.83.11.01.71.80.90.9-0.20.4-0.4-0.8-0.20.10.2
Bone: trabecular thickness1.31.76.8-0.0-2.6-2.6-1.4-1.30.4-0.50.61.40.10.0-0.6
Bone: trabecular tissue density1.01.52.20.91.01.21.31.5-1.31.41.10.7-1.41.3-1.2
Water consumed over 24 hours0.30.41.21.1-0.5-0.3-0.6-0.60.6-0.6-0.4-0.30.6-0.50.5
Number of responses in last shaping day0.10.10.20.5-0.4-0.30.0-0.1-0.1-0.0-0.00.4-0.00.0-0.1