Hub : Genes

Fhl2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Fhl2 0.03 0.03 3.4e-03 0.01 0.01 0.02 0.01 6.3e-02 1.2e-02 9.3e-04 2.8e-02
2 IC mRNA stability Fhl2 0.15 0.11 2.1e-03 0.04 0.04 0.03 0.03 1.1e-02 1.1e-02 1.4e-02 1.7e-02
3 Liver mRNA stability Fhl2 0.06 0.06 7.8e-03 0.01 0.01 0 0.01 1.1e-02 1.6e-02 1.5e-01 2.9e-02
4 Brain mRNA stability Fhl2 0.08 0.05 1.7e-04 0.03 0.04 0.04 0.04 9.3e-04 8.9e-05 1.5e-04 1.0e-04
5 PL mRNA stability Fhl2 0.31 0.11 0.0e+00 0.16 0.23 0.22 0.22 1.8e-17 9.3e-25 1.8e-23 1.8e-23
6 Adipose gene expression Fhl2 0.61 0.12 0.0e+00 0.4 0.47 0.48 0.47 1.8e-47 8.1e-58 1.5e-59 1.1e-58
7 BLA mRNA stability Fhl2 0.11 0.07 1.1e-03 0.05 0.07 0.05 0.06 1.0e-03 1.6e-04 1.4e-03 7.0e-04
8 PL isoform ratio NM_031677.2 0.05 0.05 6.5e-03 0.02 0.02 0.01 0.02 1.2e-03 3.5e-03 1.2e-02 2.7e-03
9 PL alternative TSS NM_031677.2 0.04 0.04 6.1e-03 0.01 0.02 0.02 0.02 1.4e-02 2.9e-03 6.3e-03 3.4e-03
10 OFC gene expression Fhl2 0.38 0.17 1.6e-03 0.1 0.12 0.06 0.09 2.3e-03 1.1e-03 1.5e-02 3.1e-03
11 NAcc mRNA stability Fhl2 0.12 0.07 5.2e-12 0.08 0.08 0.07 0.07 1.3e-11 1.2e-11 1.8e-10 2.5e-11
12 BLA gene expression Fhl2 0.08 0.06 2.5e-03 0.04 0.04 0.03 0.04 2.9e-03 4.8e-03 1.3e-02 5.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.01.86.20.4-2.52.1-0.7-0.70.40.2-1.52.2-0.60.81.4
Area under the delay curve1.72.63.9-0.5-0.20.8-1.5-1.5-1.9-1.82.0-1.91.9-1.9-2.0
BMI with tail0.10.31.8-0.20.7-1.30.70.30.30.00.4-0.40.2-0.1-0.4
BMI without tail0.42.22.8-1.6-0.90.8-1.5-1.5-1.7-1.71.6-1.21.7-1.6-1.6
Body weight0.10.51.8-1.3-0.90.3-0.7-0.9-0.6-0.80.4-0.00.7-0.6-0.5
Weight adjusted by age0.92.64.31.01.8-1.82.02.11.81.8-1.20.7-1.71.61.4
Bone surface0.20.52.91.7-0.90.7-0.3-0.40.2-0.1-0.80.7-0.10.10.3
Bone volume0.61.13.61.2-1.91.6-0.6-0.60.20.0-1.21.6-0.30.50.9
Breakpoint value in progressive ratio session0.81.43.9-2.0-1.51.1-1.5-1.4-1.3-1.20.6-0.21.0-1.0-0.7
Number of licking bursts0.20.61.00.8-0.30.7-1.0-0.8-1.0-0.90.4-0.70.8-0.9-0.8
Context. condit. distance diff. score0.50.61.90.0-1.00.60.10.00.60.5-1.21.4-0.60.80.9
Locomotion velocity, session 10.10.10.7-0.8-0.20.2-0.3-0.3-0.3-0.30.2-0.10.2-0.2-0.1
Locomotion distance, session 10.70.92.7-0.31.4-1.71.31.21.01.0-0.40.0-0.80.80.5
Locomotion velocity, session 21.01.34.71.12.2-2.11.21.20.50.60.0-1.0-0.30.1-0.4
Locomotion distance, session 20.60.82.90.61.7-1.70.80.70.20.10.5-1.10.1-0.2-0.7
Locomotion velocity, session 30.30.30.6-0.60.0-0.30.40.40.50.5-0.80.6-0.60.60.6
Locomotion distance, session 30.10.21.3-1.1-0.30.1-0.00.00.10.1-0.30.4-0.20.20.3
Stereotopy head waving bouts, day 30.20.20.80.4-0.70.9-0.5-0.6-0.3-0.40.20.10.3-0.3-0.2
Stereotopy head waving duration, day 30.20.30.70.3-0.50.9-0.7-0.6-0.6-0.50.4-0.30.5-0.5-0.4
Locomotion velocity, session 72.32.54.11.42.0-2.01.92.01.61.7-1.20.3-1.51.40.9
Locomotion distance, session 70.30.41.20.51.1-1.10.70.70.40.4-0.2-0.4-0.20.2-0.1
Stereotopy head waving bouts, day 70.10.10.2-0.1-0.40.3-0.0-0.00.10.1-0.30.5-0.20.20.3
Stereotopy head waving duration, day 70.50.71.30.0-0.0-0.30.70.70.90.9-1.21.0-1.01.01.0
Locomotion velocity, session 82.02.43.40.80.7-1.21.61.61.81.7-1.81.5-1.81.81.8
Locomotion distance, session 81.21.72.50.90.8-1.41.61.41.61.4-1.51.1-1.31.41.2
Degree of sensitization distance0.50.51.70.61.0-0.70.00.0-0.4-0.40.7-1.30.6-0.7-1.0
Degree of sensitization stereotypy0.20.20.60.0-0.2-0.10.40.30.50.5-0.60.8-0.60.60.6
Conditioned locomotion0.60.71.9-0.5-1.41.2-0.9-1.1-0.7-0.90.30.30.7-0.6-0.4
Cocaine response after cond. corrected1.11.62.5-0.3-0.20.5-1.2-1.2-1.5-1.51.4-1.51.6-1.6-1.6
Cocaine response after cond. not corrected0.50.71.1-0.3-0.00.1-0.7-0.8-0.9-1.00.9-1.01.0-1.1-1.0
Cocaine response before conditioning1.41.72.3-0.10.8-1.31.41.51.51.5-1.31.1-1.51.51.4
Saline control response1.01.42.71.61.0-1.01.41.21.31.2-1.10.7-1.11.11.0
Bone: connectivity density0.30.51.71.0-1.31.2-0.6-0.6-0.1-0.3-0.60.70.1-0.00.3
Bone: cortical apparent density2.74.29.41.12.8-3.12.62.62.12.2-1.30.2-1.81.71.2
Bone: cortical area0.30.41.41.2-0.0-0.40.60.40.70.5-0.90.7-0.50.60.6
Bone: cortical porosity0.20.20.80.3-0.90.9-0.4-0.30.00.0-0.60.7-0.20.20.4
Bone: cortical porosity0.40.51.20.3-1.00.9-0.2-0.10.40.3-1.11.1-0.50.60.8
Bone: cortical thickness0.40.72.41.6-0.0-0.30.60.50.80.6-1.10.9-0.70.70.8
Bone: cortical thickness0.10.10.50.6-0.0-0.10.40.20.40.3-0.70.5-0.30.30.3
Bone: cortical tissue density2.74.39.11.12.7-3.02.72.62.22.2-1.40.3-1.91.81.3
Condit. Reinf. active minus inactive responses1.01.12.0-0.8-0.30.7-1.0-1.0-1.2-1.21.4-1.11.2-1.2-1.2
Condit. Reinf. active-inactive response ratio0.91.01.4-1.2-0.50.9-1.0-1.0-1.1-1.11.2-0.81.1-1.0-0.9
Condit. Reinf. active responses0.30.40.6-0.4-0.00.2-0.5-0.5-0.7-0.60.8-0.70.7-0.7-0.7
Condit. Reinf. inactive responses0.10.20.8-0.30.8-0.90.40.40.20.2-0.0-0.4-0.00.0-0.2
Incentive salience index mean0.10.20.30.0-0.30.4-0.5-0.5-0.5-0.50.4-0.30.5-0.4-0.4
Condit. Reinf. lever presses0.40.51.20.7-0.3-0.00.50.40.70.7-1.11.1-0.80.80.9
Condit. Reinf. active minus inactive responses0.71.12.0-1.4-0.71.1-1.2-1.1-1.1-1.11.0-0.71.0-1.0-0.9
Condit. Reinf. active-inactive response ratio0.81.32.9-1.6-1.51.7-1.3-1.3-1.1-1.00.90.10.8-0.7-0.5
Condit. Reinf. active responses0.60.81.3-0.6-0.00.4-0.8-0.8-1.0-1.00.9-1.11.1-1.1-1.1
Condit. Reinf. inactive responses0.50.72.31.11.5-1.40.90.90.60.5-0.4-0.7-0.30.2-0.1
Condit. Reinf. lever presses0.20.30.5-0.2-0.40.7-0.7-0.6-0.6-0.50.2-0.40.5-0.5-0.4
Condit. Reinf. lever reinforcers received0.70.91.8-0.60.20.3-0.8-0.8-1.0-1.01.0-1.31.1-1.2-1.3
Conditioned reinforcement - actives0.20.96.0-2.4-0.2-0.4-0.6-0.5-0.7-0.70.8-0.70.7-0.7-0.8
Conditioned reinforcement - inactives0.51.37.7-2.80.2-1.30.90.80.80.9-0.70.8-0.80.90.6
Conditioned locomotion0.71.02.8-1.50.7-1.71.31.01.10.9-0.50.4-0.70.80.5
Patch foraging indifference point 0 sec0.61.63.41.81.0-1.11.41.41.41.3-1.20.6-1.21.21.0
Patch foraging indifference point AUC0.10.42.0-1.40.3-0.5-0.1-0.2-0.3-0.40.7-0.70.5-0.5-0.4
Delay disc. indifference point, 0s delay1.11.22.8-0.11.4-1.71.41.41.11.2-0.70.2-1.01.00.8
Delay disc. indifference point, 16s delay2.23.14.2-1.1-1.41.8-2.0-2.0-2.0-2.01.8-1.21.9-1.8-1.7
Delay disc. indifference point, 2s delay0.91.01.7-0.5-0.20.2-0.8-0.9-1.1-1.11.3-1.11.2-1.2-1.3
Delay disc. indifference point, 24s delay0.20.20.4-0.1-0.10.5-0.6-0.5-0.7-0.50.6-0.60.5-0.5-0.5
Delay disc. indifference point, 4s delay0.10.10.3-0.20.5-0.60.20.1-0.1-0.10.3-0.50.2-0.3-0.4
Delay disc. indifference point, 8s delay1.11.82.70.3-0.21.0-1.4-1.3-1.6-1.51.6-1.61.6-1.6-1.6
Indifference point function ln k0.20.72.81.71.6-1.00.40.70.00.20.1-1.1-0.0-0.1-0.5
Indifference point function log k0.20.72.81.71.6-1.00.40.70.00.20.1-1.1-0.0-0.1-0.5
Patch foraging total patch changes 0 sec0.30.92.81.70.9-0.91.11.01.00.9-0.80.3-0.70.70.5
Patch foraging total patch changes 12 sec0.91.32.6-0.1-0.2-0.61.10.81.41.1-1.61.5-1.21.21.4
Patch foraging total patch changes 18 sec0.10.20.40.40.6-0.40.20.00.0-0.20.6-0.60.3-0.3-0.3
Patch foraging total patch changes 24 sec0.31.01.8-0.30.4-1.01.31.01.31.1-0.90.9-1.01.11.1
Patch foraging total patch changes 6 sec0.30.50.80.70.4-0.40.90.80.90.8-0.60.5-0.70.70.7
Patch foraging time to switch 0 sec0.10.41.10.0-0.60.50.10.20.40.5-0.71.1-0.70.70.9
Patch foraging water rate 0 sec0.31.12.0-0.6-0.10.1-0.9-1.0-1.2-1.31.1-1.31.3-1.3-1.4
Patch foraging water rate 12 sec0.10.61.71.30.50.2-0.3-0.2-0.6-0.50.9-1.10.6-0.7-0.9
Patch foraging water rate 18 sec0.10.21.41.20.40.1-0.20.1-0.3-0.10.0-0.50.1-0.2-0.4
Patch foraging water rate 24 sec0.20.21.61.30.60.2-0.00.1-0.2-0.10.4-0.60.2-0.2-0.4
Patch foraging water rate 6 sec0.50.82.50.80.9-0.2-0.5-0.2-1.0-0.71.1-1.60.8-0.9-1.0
Seeking ratio, delayed vs. immediate footshock0.60.96.4-2.5-1.30.2-0.2-0.30.20.1-0.51.2-0.30.40.8
Distance traveled before self-admin0.20.41.7-0.0-1.30.7-0.4-0.40.10.0-0.61.0-0.20.30.6
Distance traveled after self-admin1.32.37.0-0.5-1.70.70.40.41.31.2-2.12.6-1.61.72.1
Extensor digitorum longus weight2.18.332.91.85.7-5.23.33.21.51.70.8-2.6-0.90.6-0.8
Bone: elastic displacement1.11.42.8-0.2-1.31.7-1.6-1.4-1.3-1.30.9-0.51.1-1.1-0.8
Bone: elastic work0.50.62.10.4-1.41.4-0.9-1.0-0.5-0.6-0.10.50.4-0.40.0
Bone: endosteal estimation0.10.20.3-0.1-0.50.4-0.5-0.5-0.4-0.50.2-0.10.5-0.4-0.4
Bone: endosteal perimeter0.10.10.2-0.5-0.40.3-0.4-0.5-0.4-0.40.2-0.10.4-0.4-0.3
Epididymis fat weight0.00.20.6-0.70.4-0.5-0.1-0.1-0.3-0.30.6-0.70.5-0.4-0.6
Delta time in closed arm before/after self-admin0.40.41.71.3-0.00.7-0.6-0.4-0.6-0.50.5-0.60.5-0.5-0.5
Delta time in open arm before/after self-admin0.30.33.11.8-0.20.7-0.1-0.20.1-0.0-0.20.2-0.00.10.1
Diff in mean of infusions in LGA sessions0.30.61.50.3-1.21.0-1.0-1.0-0.8-0.80.40.10.6-0.6-0.4
Delay discount exponential model param2.02.74.00.50.3-0.81.61.61.91.8-2.01.9-2.02.02.0
Extinction: sum of active levers before priming1.42.28.6-1.6-2.92.1-1.5-1.9-0.9-1.20.31.10.9-0.6-0.2
Active lever presses in extinction session 61.31.32.0-1.4-0.60.1-1.0-1.2-1.2-1.31.4-1.01.4-1.3-1.4
Bone: final force0.61.02.10.8-0.0-0.51.00.81.21.0-1.41.3-1.11.11.1
Bone: final moment0.50.81.70.80.0-0.50.90.71.10.8-1.31.0-0.90.90.9
Food consumed during 24 hour testing period0.10.31.3-1.10.3-0.5-0.1-0.2-0.4-0.40.4-0.70.5-0.5-0.7
Glucose0.81.21.7-0.6-1.01.3-1.3-1.3-1.3-1.21.1-0.61.2-1.1-1.0
Heart weight0.20.30.70.30.4-0.1-0.4-0.2-0.6-0.50.6-0.80.5-0.6-0.6
Delay discount hyperbolic model param1.92.43.80.40.2-0.71.41.41.81.7-1.91.9-1.91.91.9
Intermittent access intake day 1-15 change0.10.42.4-1.6-0.4-0.20.20.30.40.5-0.60.7-0.50.60.5
Intermittent access intake escalation0.10.41.3-1.1-0.2-0.30.30.50.50.7-0.80.8-0.70.70.7
Intermittent access intake escalation 20.20.32.2-1.5-0.70.4-0.5-0.2-0.2-0.0-0.20.4-0.10.10.1
Intermitt. access day 1 inactive lever presses0.00.41.7-1.3-1.20.4-0.1-0.40.10.0-0.51.1-0.10.30.3
Intermitt. access day 15 inactive lever presses0.21.01.41.10.7-0.71.21.11.11.2-0.90.8-1.11.10.9
Intermitt. access escalation Index0.10.30.70.80.8-0.30.50.70.50.6-0.4-0.0-0.50.40.5
Intermittent access day 1 total infusions2.06.116.3-4.0-1.91.3-2.4-2.6-2.5-2.62.5-1.42.6-2.4-2.3
Intermittent access day 15 total infusions0.61.612.4-3.5-0.90.2-1.0-0.9-0.9-0.80.8-0.40.8-0.7-0.8
Intermittent access terminal intake (last 3 days)1.42.517.1-4.1-1.20.2-1.2-1.3-1.2-1.21.2-0.61.2-1.1-1.2
Intermittent access total infusions2.42.812.9-3.6-1.20.6-1.5-1.5-1.6-1.51.5-0.91.5-1.4-1.5
Intermittent access day 1 locomotion0.71.26.6-2.6-0.5-0.3-0.7-0.9-0.9-1.01.2-0.71.0-1.0-1.0
Intermittent access day 15 total locomotion0.20.63.9-2.00.8-1.40.50.60.30.30.0-0.3-0.20.1-0.1
Intermittent access total locomotion0.50.64.9-2.20.3-0.9-0.1-0.1-0.2-0.30.6-0.60.4-0.4-0.5
Intermittent access standard deviation0.10.84.5-2.1-1.40.8-0.8-0.9-0.5-0.50.10.50.4-0.2-0.2
Left kidney weight0.10.41.4-1.0-0.5-0.10.10.20.40.4-1.20.9-0.60.60.8
Right kidney weight0.42.54.7-0.40.5-1.71.61.51.81.6-2.21.6-1.71.71.8
Cocaine induced anxiety0.71.85.42.31.4-0.91.51.51.41.4-1.00.5-1.31.21.1
Post-drug Anxiety1.21.42.91.71.1-1.01.51.31.41.2-0.90.6-1.11.10.9
Baseline Anxiety0.60.93.3-1.8-0.60.4-0.7-1.0-0.9-1.01.0-0.51.0-1.0-1.0
Tail length0.84.47.2-2.3-2.42.6-2.7-2.5-2.3-2.21.3-0.62.0-1.9-1.4
Length with tail0.41.84.8-1.8-2.21.9-1.6-1.6-1.1-1.20.10.50.9-0.8-0.3
Length without tail0.00.20.50.0-0.2-0.30.40.20.60.3-0.70.7-0.40.40.5
Times rat made contact with spout2.52.94.4-0.7-1.51.8-2.1-2.0-2.0-1.91.4-1.01.8-1.8-1.6
Lifetime Intake1.72.19.9-3.1-1.00.3-1.2-1.3-1.3-1.31.4-0.81.4-1.3-1.3
Liver weight, left1.32.23.40.2-1.31.2-1.8-1.9-1.7-1.81.0-1.01.8-1.7-1.5
Liver weight, right0.91.53.50.4-1.71.9-1.5-1.7-1.2-1.40.7-0.11.2-1.1-0.9
Locomotor activity0.10.20.5-0.7-0.60.5-0.6-0.5-0.4-0.40.4-0.00.3-0.3-0.2
Locomotor testing distance0.10.31.2-0.3-1.11.0-0.4-0.30.00.0-0.40.9-0.20.30.6
Locomotor testing rearing0.20.82.10.5-0.90.80.10.20.60.7-1.31.4-0.90.91.2
Locomotion in novel chamber0.91.35.50.32.1-2.31.00.80.10.10.7-1.40.3-0.3-1.0
Locomotion in novel chamber post-restriction0.20.52.9-0.71.0-1.70.80.50.30.20.1-0.50.00.0-0.4
Fecal boli incidents, locomotor time 10.30.83.41.80.7-0.1-0.2-0.4-0.6-0.70.8-1.20.8-0.9-0.9
Change in fecal boli incidents, locomotor task0.30.31.8-1.3-0.5-0.10.1-0.00.30.2-0.50.7-0.30.30.4
Time >=10cm from walls, locomotor time 11.21.55.82.32.4-1.41.01.20.20.50.4-1.4-0.2-0.0-0.4
Bouts of movement, locomotor time 12.63.48.81.01.5-0.4-0.6-0.8-1.5-1.72.6-3.02.1-2.2-2.5
Total resting periods, locomotor time 12.42.77.41.31.7-0.6-0.3-0.5-1.2-1.42.3-2.71.7-1.9-2.2
Rest time, locomotor task time 12.23.54.7-1.8-1.11.4-1.9-2.1-2.0-2.22.0-1.52.2-2.2-1.9
Distance moved, locomotor task time 10.00.10.40.40.7-0.40.20.50.10.4-0.1-0.3-0.30.30.1
Vertical activity count, locomotor time 10.21.43.01.70.2-0.10.81.11.11.3-1.21.2-1.41.41.4
Time >=10cm from walls, locomotor time 20.10.21.41.2-0.10.3-0.3-0.3-0.3-0.30.3-0.20.3-0.3-0.2
Bouts of movement, locomotor time 20.20.51.4-0.81.1-1.20.40.2-0.1-0.20.8-1.00.4-0.5-0.8
Total resting periods, locomotor time 20.10.51.8-1.30.9-1.20.40.2-0.0-0.10.7-0.80.3-0.3-0.7
Rest time, locomotor task time 20.10.20.9-0.9-0.40.6-0.4-0.4-0.3-0.30.3-0.10.3-0.3-0.1
Distance moved, locomotor task time 20.30.51.91.41.0-0.70.10.3-0.3-0.10.6-1.00.3-0.4-0.5
Vertical activity count, locomotor time 20.30.62.51.60.7-0.80.80.80.70.7-0.40.3-0.70.60.6
Light reinforcement 10.31.56.4-0.41.9-2.51.71.31.20.9-0.1-0.4-0.50.5-0.1
Light reinforcement 20.10.20.80.50.4-0.90.40.10.2-0.10.3-0.30.3-0.2-0.4
Bone: marrow area0.10.10.2-0.1-0.40.3-0.4-0.5-0.3-0.40.2-0.10.4-0.4-0.4
Bone: maximum diameter0.10.10.50.5-0.70.4-0.2-0.30.1-0.0-0.50.6-0.10.10.3
Bone: maximum force0.40.81.51.20.0-0.50.90.61.10.8-1.21.1-0.80.90.9
Bone: maximum moment0.30.61.61.20.1-0.50.80.50.90.7-1.10.8-0.60.70.7
Mean time between licks in bursts0.20.93.00.71.6-1.71.21.20.70.8-0.4-0.4-0.60.50.1
Mean num. licks in bursts0.10.21.3-1.2-0.20.0-0.1-0.2-0.1-0.30.5-0.20.3-0.2-0.3
Cd content in liver2.52.89.7-3.1-2.32.1-1.9-1.8-1.4-1.40.50.21.1-1.0-0.5
Co content in liver1.31.57.7-2.8-1.31.3-1.3-1.2-1.0-1.00.5-0.10.8-0.8-0.5
Cu content in liver0.10.20.7-0.9-0.60.5-0.4-0.4-0.3-0.3-0.00.10.3-0.2-0.1
Fe content in liver0.81.04.00.2-2.01.8-0.8-0.8-0.0-0.2-0.81.4-0.10.20.8
K content in liver1.11.16.02.51.4-1.21.11.00.70.7-0.2-0.3-0.50.50.1
Mg content in liver0.40.52.21.50.7-0.60.70.70.60.6-0.50.1-0.50.50.3
Mn content in liver0.80.91.60.41.0-0.91.31.21.11.1-0.30.5-1.01.00.8
Na content in liver1.21.44.42.1-0.40.30.60.61.01.0-1.71.4-1.11.21.3
Rb content in liver0.91.14.30.32.1-2.01.31.00.60.50.7-1.0-0.20.1-0.4
Se content in liver0.10.10.2-0.00.0-0.2-0.1-0.3-0.3-0.40.5-0.40.4-0.4-0.4
Sr content in liver0.50.41.0-1.0-0.00.4-0.7-0.5-0.7-0.70.6-0.80.7-0.8-0.7
Zn content in liver0.00.00.3-0.5-0.20.1-0.2-0.1-0.2-0.1-0.2-0.00.1-0.1-0.1
Bone: minimum diameter0.20.30.70.80.5-0.80.70.50.60.5-0.50.2-0.40.40.2
Time in familiar zone, hab. session 11.92.13.2-1.1-1.51.5-1.7-1.8-1.6-1.71.2-0.71.6-1.5-1.3
Time in novel zone, hab. session 10.00.00.2-0.3-0.30.4-0.3-0.1-0.20.00.00.2-0.10.10.2
Total zone transitions, hab. session 12.23.14.30.61.2-1.62.02.02.02.1-1.91.4-2.02.01.8
Total locomotion distance, hab. session 10.50.72.00.11.3-1.41.11.00.70.8-0.4-0.2-0.60.50.3
Locomotion velocity, hab. session 10.81.22.70.51.4-1.61.41.41.11.2-0.80.2-1.00.90.7
Time in familiar zone, hab. session 20.20.20.4-0.4-0.60.6-0.7-0.5-0.5-0.40.1-0.00.4-0.4-0.2
Time in novel zone, hab. session 20.00.00.00.0-0.10.10.1-0.00.10.10.00.2-0.00.10.1
Total zone transitions, hab. session 20.10.10.7-0.80.2-0.50.10.1-0.0-0.10.3-0.20.1-0.1-0.1
Total locomotion distance, hab. session 20.70.92.4-1.01.0-0.8-0.2-0.2-0.7-0.71.2-1.60.9-0.9-1.2
Locomotion velocity, hab. session 20.40.61.5-1.01.1-1.00.10.1-0.4-0.30.8-1.20.5-0.6-0.8
Novel to familiar place preference ratio2.12.73.80.9-1.11.5-1.9-1.9-1.8-2.01.5-1.31.9-1.9-1.7
Novelty place preference2.02.63.60.9-1.11.5-1.8-1.9-1.8-1.91.5-1.21.9-1.8-1.7
Time in novel zone, NPP test2.53.14.40.7-1.41.8-2.1-2.1-2.0-2.11.6-1.22.0-1.9-1.7
Total zone transitions, NPP test0.30.41.6-0.71.1-1.30.70.80.40.5-0.2-0.2-0.50.40.2
Total locomotion distance, NPP test0.30.41.4-0.31.2-1.00.30.4-0.10.00.4-1.00.2-0.3-0.5
Locomotion velocity, NPP test0.50.72.90.11.7-1.60.91.00.40.50.0-0.8-0.30.1-0.2
Intraocular pressure0.40.72.2-1.31.2-1.50.50.4-0.2-0.10.6-1.10.4-0.4-0.7
Delta distance traveled before/after self-admin0.60.61.0-0.30.1-0.30.70.80.80.9-1.00.9-1.01.01.0
Delta ambulatory time before/after self-admin0.30.60.8-0.60.2-0.50.80.80.80.9-0.80.8-0.90.90.9
Parametrial fat weight0.10.11.0-1.0-0.4-0.1-0.0-0.30.0-0.30.20.20.2-0.1-0.1
Pavlov. Cond. lever latency0.60.82.00.00.6-0.1-0.4-0.4-0.8-0.71.3-1.40.9-1.0-1.3
Pavlov. Cond. magazine entry latency0.10.10.30.3-0.50.5-0.2-0.3-0.1-0.10.30.20.1-0.00.1
Pavlov. Cond. change in total contacts0.10.10.2-0.0-0.20.2-0.3-0.5-0.4-0.50.4-0.20.4-0.4-0.4
Pavlov. Cond. index score0.10.20.70.2-0.80.7-0.3-0.4-0.1-0.1-0.20.6-0.00.10.3
Pavlov. Cond. latency score0.20.20.70.1-0.90.6-0.2-0.20.10.1-0.50.8-0.20.30.6
Pavlov. Cond. lever contacts0.40.51.20.1-0.40.00.40.30.60.6-1.01.1-0.80.81.0
Pavlov. Cond. magazine entry number0.20.20.8-0.10.9-0.90.40.40.10.1-0.0-0.5-0.0-0.1-0.3
Pavlov. Cond. intertrial magazine entries0.50.61.20.30.10.1-0.8-0.7-0.9-0.90.6-1.11.0-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.2-0.70.6-0.4-0.5-0.2-0.30.10.30.2-0.10.0
Pavlov. Cond. response bias0.10.10.50.5-0.70.6-0.2-0.30.0-0.1-0.10.6-0.00.10.3
Pavlov. Cond. lever latency0.10.10.30.40.2-0.2-0.1-0.2-0.3-0.40.5-0.50.4-0.4-0.5
Pavlov. Cond. magazine entry latency1.11.52.4-0.20.3-0.51.21.31.51.5-1.31.3-1.51.51.5
Pavlov. Cond. change in total contacts0.10.10.6-0.0-0.70.8-0.5-0.4-0.2-0.2-0.30.20.2-0.10.0
Pavlov. Cond. index score0.20.30.6-0.5-0.40.20.20.30.50.5-0.60.8-0.50.60.7
Pavlov. Cond. latency score0.20.20.4-0.5-0.1-0.00.40.40.60.6-0.60.6-0.60.60.7
Pavlov. Cond. lever contacts0.10.10.5-0.5-0.60.7-0.3-0.2-0.10.0-0.30.4-0.10.10.3
Pavlov. Cond. magazine entry number0.60.81.40.50.00.1-0.7-0.8-1.0-1.11.0-1.11.1-1.1-1.2
Pavlov. Cond. intertrial magazine entries0.51.02.7-0.71.3-1.20.10.0-0.6-0.51.3-1.60.8-0.9-1.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.2-0.20.10.30.40.50.5-0.60.7-0.60.60.7
Pavlov. Cond. response bias0.50.81.6-0.2-0.50.30.40.60.80.9-1.21.2-1.01.11.2
Time in closed arm before self-admin1.01.74.1-2.0-1.61.4-1.4-1.5-1.3-1.30.8-0.11.1-1.0-0.8
Time in closed arm after self-admin0.40.42.3-1.5-1.10.6-0.4-0.4-0.1-0.0-0.50.8-0.10.20.4
Time in open arm before self-admin0.30.41.8-0.01.1-1.30.60.70.30.30.2-0.6-0.10.1-0.1
Time in open arm after self-admin0.40.53.41.80.3-0.00.50.50.60.5-0.50.4-0.60.50.5
Bone: periosteal estimation0.10.10.40.5-0.60.2-0.0-0.20.20.0-0.60.6-0.10.20.3
Bone: periosteal perimeter0.20.40.80.3-0.90.7-0.7-0.8-0.6-0.70.10.00.6-0.5-0.4
Bone: post-yield work0.50.91.60.80.3-0.71.00.91.11.0-1.31.0-1.01.11.0
Progressive ratio test 1 active lever presses0.61.05.0-2.20.0-0.9-0.4-0.5-0.6-0.71.1-0.90.9-0.9-1.0
Progressive ratio test 1 breakpoint0.61.14.8-2.2-0.1-0.7-0.5-0.7-0.7-0.91.2-0.91.0-1.0-1.1
Progressive ratio test 1 inactive lever presses0.30.93.7-1.9-0.4-0.90.80.50.90.7-0.81.2-0.70.80.7
Progressive ratio test 2 active lever presses0.50.76.0-2.40.7-1.30.30.50.10.20.1-0.5-0.1-0.0-0.2
Progressive ratio test 2 breakpoint0.60.75.4-2.30.8-1.40.30.50.10.20.1-0.6-0.0-0.1-0.3
Progressive ratio test 2 inactive lever presses0.41.15.4-2.3-0.0-1.30.80.80.80.9-0.80.9-0.90.90.7
Incentive Sensitization - Responses0.20.51.00.30.9-0.70.61.00.60.9-0.80.2-0.90.70.6
Incentive Sensitization - Breakpoint0.30.71.30.11.0-0.80.81.10.71.0-0.90.2-1.00.80.7
Sum of active levers in priming session hrs 5-62.72.54.4-0.5-1.71.7-2.1-2.0-1.9-1.81.3-0.71.6-1.6-1.3
Progressive ratio0.41.33.4-0.41.1-0.3-0.4-0.4-1.0-1.01.8-1.81.2-1.3-1.6
Food seeking constrained by brief footshock0.10.10.4-0.10.7-0.10.30.40.20.30.5-0.2-0.20.20.1
Seeking ratio, punishment vs. effort0.30.81.60.6-0.40.00.60.60.90.9-1.11.3-1.01.01.2
Retroperitoneal fat weight0.10.52.2-1.00.6-1.51.00.60.90.5-0.20.1-0.30.40.2
Reaction time number correct0.10.41.90.41.4-1.10.80.80.50.40.2-0.6-0.20.1-0.3
Reaction time mean minus median0.10.51.2-0.6-1.11.0-1.1-0.8-0.7-0.60.10.10.4-0.4-0.0
Reaction time mean minus median AUC0.10.40.9-1.0-0.90.8-0.9-0.6-0.6-0.40.00.10.3-0.30.0
Reaction time num false alarms0.30.51.9-0.11.4-1.40.90.80.50.40.2-0.6-0.20.2-0.3
Reaction time num false alarms AUC0.40.92.90.31.7-1.71.21.10.70.7-0.0-0.6-0.40.4-0.2
Reaction time trials correct on left0.10.41.90.41.4-1.10.80.80.50.40.2-0.6-0.20.1-0.3
Reaction time trials on left0.10.41.70.41.3-1.00.80.70.40.30.2-0.6-0.10.0-0.3
Reaction time mean0.71.63.9-1.8-2.02.0-1.6-1.5-1.1-1.00.30.30.8-0.7-0.1
Reaction time mean AUC0.61.53.2-1.7-1.81.8-1.5-1.4-1.1-1.10.50.10.9-0.8-0.3
Median of all reaction times1.21.84.4-2.0-2.12.1-1.6-1.6-1.1-1.10.40.30.9-0.8-0.2
Reaction time omissions0.10.20.5-0.5-0.70.5-0.4-0.2-0.10.0-0.70.5-0.20.20.3
Reaction time false alarm rate0.20.31.20.10.9-1.10.80.70.50.5-0.2-0.1-0.40.40.1
Reaction time premature initiation rate0.10.10.30.3-0.40.40.10.00.20.2-0.20.5-0.30.40.3
Reaction time premature initiations0.00.10.30.60.20.00.40.30.40.3-0.10.2-0.30.30.2
Std. dev. reaction times0.20.61.8-1.0-1.21.3-1.1-0.8-0.7-0.5-0.20.30.2-0.20.2
Reaction time trials completed0.10.41.70.41.3-1.00.80.70.40.30.2-0.6-0.10.0-0.3
Reaction time trials AUC0.10.41.60.41.3-0.90.70.70.40.30.2-0.6-0.10.0-0.3
Run reversals in cocaine runway, females0.30.31.71.30.9-0.60.50.50.20.30.1-0.3-0.20.2-0.1
Run reversals in cocaine runway, males0.40.43.4-1.8-0.3-0.3-0.3-0.4-0.4-0.50.4-0.30.5-0.5-0.4
Latency to leave start box in cocaine runway1.72.44.01.31.2-2.01.91.71.81.6-1.40.9-1.51.51.2
Latency to leave start box in cocaine runway, F2.12.63.61.30.9-1.31.91.71.91.8-1.61.4-1.81.81.7
Latency to leave start box in cocaine runway, M1.00.94.80.71.5-2.21.10.90.60.5-0.3-0.5-0.30.3-0.1
Std. dev. time between licks in bursts0.20.41.61.30.7-0.4-0.0-0.1-0.4-0.40.4-1.00.5-0.6-0.8
Total sessions with >9 infusions0.20.30.6-0.7-0.1-0.7-0.1-0.4-0.2-0.50.8-0.50.6-0.6-0.6
Short access day 1 total inactive lever presses0.30.72.0-0.60.5-1.41.10.91.00.9-0.60.5-0.70.70.5
Short access day 10 total inactive lever presses0.10.41.1-0.3-0.40.10.40.30.60.6-0.91.0-0.70.80.8
Short access day 1 total infusions0.30.63.4-1.80.5-1.60.40.30.10.00.4-0.40.1-0.2-0.3
Short access day 10 total infusions3.25.310.1-3.2-1.10.7-2.1-2.2-2.3-2.42.7-2.02.6-2.5-2.5
Short access total infusions1.42.04.8-2.2-0.6-0.1-1.1-1.3-1.3-1.51.7-1.21.6-1.5-1.6
Short access day 1 locomotion0.30.42.20.01.0-1.50.90.70.60.40.1-0.3-0.20.2-0.0
Short access day 10 total locomotion0.00.20.7-0.8-0.2-0.2-0.4-0.4-0.4-0.40.5-0.40.5-0.4-0.4
Short access total locomotion0.30.41.80.31.1-1.30.70.60.40.30.3-0.5-0.0-0.0-0.2
One hour access (0.3 mA shock)5.36.211.6-3.4-2.11.4-2.7-2.8-2.7-2.82.3-1.42.7-2.5-2.4
Compulsive drug intake0.81.29.73.11.1-0.30.70.90.60.7-0.5-0.1-0.60.50.5
One hour access (shock baseline)1.84.816.8-4.1-1.91.0-2.2-2.3-2.2-2.21.9-1.02.1-2.0-2.0
Social response proportion0.50.74.2-2.0-1.10.5-0.7-0.8-0.6-0.60.50.30.4-0.3-0.2
Social responses0.71.02.8-1.1-1.71.4-1.2-1.2-0.8-0.80.50.40.7-0.5-0.4
Social time1.21.87.5-1.4-2.72.1-1.4-1.4-0.5-0.6-0.81.60.10.00.6
Soleus weight0.61.65.01.52.2-2.21.51.50.91.0-0.2-0.7-0.70.60.1
Bone: stiffness1.22.23.20.40.7-1.31.81.51.81.7-1.81.5-1.61.71.5
Tibialis anterior weight1.24.016.21.24.0-3.62.22.30.91.20.7-1.9-0.70.4-0.5
Time to tail flick, vehicle, before self-admin0.60.71.71.0-1.11.3-0.9-1.1-0.7-0.90.40.00.7-0.6-0.5
Time to tail flick, vehicle, after self-admin0.20.53.11.8-0.61.1-0.5-0.5-0.4-0.4-0.00.20.2-0.2-0.1
Time to tail flick, test, before self-admin1.11.25.5-0.82.4-1.70.71.10.00.30.7-1.70.0-0.2-0.6
Time to tail flick, test, after self-admin0.20.20.6-0.50.5-0.80.50.10.2-0.10.5-0.40.3-0.2-0.5
Delta time to tail flick, vehicle, before/after SA0.10.10.60.80.4-0.20.20.30.20.3-0.2-0.0-0.20.20.2
Delta time to tail flick, test, before/after SA0.40.52.90.2-1.71.0-0.3-0.90.1-0.4-0.21.10.3-0.00.1
Tibia length0.41.14.02.0-1.00.50.30.10.80.6-1.51.6-0.80.91.1
Ambulatory time before self-admin0.10.31.4-0.1-1.20.8-0.5-0.5-0.1-0.1-0.30.7-0.00.10.4
Ambulatory time after self-admin0.91.53.8-1.1-1.00.10.50.51.11.1-1.61.9-1.31.41.7
Bone: tissue strength0.00.00.30.50.3-0.30.20.10.10.1-0.1-0.1-0.00.0-0.1
Total heroin consumption4.65.47.8-2.1-2.12.0-2.6-2.8-2.6-2.72.2-1.32.6-2.4-2.2
Bone: trabecular number1.01.95.40.5-2.31.9-0.4-0.40.70.5-1.72.3-0.91.01.6
Bone: trabecular spacing0.60.83.1-1.01.7-1.80.90.90.20.40.4-0.8-0.20.1-0.2
Bone: trabecular thickness1.21.76.80.0-2.62.6-1.4-1.3-0.4-0.5-0.61.40.10.00.6
Bone: trabecular tissue density0.81.52.2-0.91.0-1.21.31.51.31.4-1.10.7-1.41.31.2
Water consumed over 24 hours0.20.41.2-1.1-0.50.3-0.6-0.6-0.6-0.60.4-0.30.6-0.5-0.5
Number of responses in last shaping day0.00.10.2-0.5-0.40.30.0-0.10.1-0.00.00.4-0.00.00.1