Hub : Genes

Fbxo47

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Fbxo47 0.04 0.04 7.8e-04 0.05 0.04 0.04 0.05 7.3e-05 7.1e-04 3.0e-04 8.7e-05
2 Brain gene expression Fbxo47 0.07 0.06 1.8e-06 0.04 0.06 0.05 0.05 8.6e-05 5.0e-06 1.5e-05 2.7e-05
3 Liver gene expression Fbxo47 0.05 0.04 8.7e-07 0.04 0.04 0.04 0.03 4.9e-05 2.6e-05 6.5e-05 1.1e-04
4 PL gene expression Fbxo47 0.03 0.02 3.5e-03 0.02 0.02 0.01 0.02 1.2e-03 3.6e-03 7.4e-03 1.9e-03
5 RMTg mRNA stability Fbxo47 0.11 0.1 8.5e-03 0.07 0.06 0.07 0.07 6.4e-03 8.7e-03 5.0e-03 7.9e-03
6 OFC gene expression Fbxo47 0.19 0.17 6.8e-03 0.06 0.01 0.05 0.04 1.9e-02 2.2e-01 3.1e-02 4.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
Bone: apparent density1.63.03.9-2.01.81.8-1.71.5-1.5
Area under the delay curve0.71.11.4-0.71.11.1-1.01.1-1.2
BMI with tail1.86.27.42.7-2.6-2.52.4-2.42.3
BMI without tail0.94.85.52.3-2.3-2.22.2-2.02.0
Body weight7.432.333.95.8-5.8-5.85.4-5.75.6
Weight adjusted by age0.10.20.30.6-0.4-0.40.5-0.50.5
Bone surface0.00.00.1-0.0-0.1-0.10.0-0.30.3
Bone volume0.00.10.2-0.50.30.3-0.20.0-0.0
Breakpoint value in progressive ratio session1.22.22.51.5-1.6-1.51.3-1.61.4
Number of licking bursts0.20.80.9-0.90.80.8-1.00.9-0.8
Context. condit. distance diff. score0.40.50.60.7-0.7-0.70.8-0.60.6
Locomotion velocity, session 11.21.41.90.9-1.1-1.11.4-1.21.3
Locomotion distance, session 13.95.05.62.4-2.3-2.32.2-2.02.1
Locomotion velocity, session 20.80.91.20.8-1.0-1.01.0-0.91.1
Locomotion distance, session 21.01.41.61.3-1.2-1.31.2-1.01.2
Locomotion velocity, session 30.10.20.20.4-0.4-0.40.3-0.40.4
Locomotion distance, session 30.50.60.70.8-0.8-0.80.8-0.70.8
Stereotopy head waving bouts, day 33.74.45.0-2.22.12.1-2.22.0-2.0
Stereotopy head waving duration, day 30.70.81.0-1.00.90.9-1.00.9-0.9
Locomotion velocity, session 70.60.71.01.0-0.9-0.90.9-0.60.6
Locomotion distance, session 70.10.10.10.3-0.3-0.30.4-0.10.0
Stereotopy head waving bouts, day 71.11.31.9-1.41.31.2-1.20.8-0.9
Stereotopy head waving duration, day 70.20.30.6-0.80.60.6-0.60.1-0.3
Locomotion velocity, session 86.78.18.73.0-2.9-2.92.8-2.72.8
Locomotion distance, session 81.82.62.81.7-1.6-1.61.6-1.61.6
Degree of sensitization distance0.10.10.20.4-0.4-0.40.5-0.30.2
Degree of sensitization stereotypy1.61.82.4-1.51.41.4-1.31.0-1.1
Conditioned locomotion0.20.20.3-0.40.50.5-0.50.5-0.5
Cocaine response after cond. corrected1.62.43.5-1.91.61.6-1.41.4-1.4
Cocaine response after cond. not corrected2.53.65.0-2.22.02.0-1.81.7-1.7
Cocaine response before conditioning0.70.91.3-0.90.90.9-1.20.9-0.9
Saline control response0.00.10.1-0.10.20.2-0.40.2-0.3
Bone: connectivity density2.43.84.3-2.12.12.0-2.01.8-1.8
Bone: cortical apparent density3.65.77.6-2.82.62.6-2.32.0-2.0
Bone: cortical area0.20.30.5-0.60.50.5-0.70.4-0.4
Bone: cortical porosity1.21.32.0-1.01.01.0-1.01.4-1.4
Bone: cortical porosity1.21.32.0-0.91.01.0-0.91.4-1.4
Bone: cortical thickness1.32.23.1-1.71.61.6-1.51.3-1.2
Bone: cortical thickness4.75.76.1-2.42.42.4-2.52.4-2.3
Bone: cortical tissue density3.65.77.6-2.82.62.6-2.32.0-2.0
Condit. Reinf. active minus inactive responses0.40.50.5-0.70.70.7-0.70.7-0.7
Condit. Reinf. active-inactive response ratio0.80.91.1-0.80.90.9-0.91.1-1.0
Condit. Reinf. active responses0.60.71.0-1.00.90.9-0.80.8-0.8
Condit. Reinf. inactive responses0.40.50.9-0.90.80.8-0.60.7-0.6
Incentive salience index mean1.31.61.8-1.31.21.2-1.31.3-1.3
Condit. Reinf. lever presses1.21.82.0-1.31.31.3-1.31.4-1.4
Condit. Reinf. active minus inactive responses0.60.91.2-0.80.80.9-1.11.1-1.1
Condit. Reinf. active-inactive response ratio0.30.40.5-0.60.60.6-0.60.6-0.7
Condit. Reinf. active responses1.11.52.0-1.01.11.1-1.41.4-1.3
Condit. Reinf. inactive responses1.72.52.9-1.41.51.5-1.71.7-1.6
Condit. Reinf. lever presses0.10.10.2-0.10.10.1-0.40.3-0.3
Condit. Reinf. lever reinforcers received1.01.51.9-1.01.11.1-1.41.3-1.3
Conditioned reinforcement - actives0.31.42.1-1.00.91.0-1.11.4-1.5
Conditioned reinforcement - inactives0.10.20.4-0.00.10.2-0.20.7-0.7
Conditioned locomotion1.42.02.5-1.31.41.4-1.31.6-1.6
Patch foraging indifference point 0 sec0.82.32.5-1.51.51.5-1.61.5-1.5
Patch foraging indifference point AUC0.10.10.4-0.1-0.1-0.10.3-0.60.6
Delay disc. indifference point, 0s delay1.92.12.5-1.61.51.5-1.21.4-1.5
Delay disc. indifference point, 16s delay0.40.60.7-0.70.80.8-0.80.5-0.7
Delay disc. indifference point, 2s delay2.62.93.2-1.71.71.7-1.51.8-1.7
Delay disc. indifference point, 24s delay0.00.00.1-0.10.20.1-0.3-0.30.2
Delay disc. indifference point, 4s delay0.50.50.8-0.60.90.9-0.40.7-0.6
Delay disc. indifference point, 8s delay0.50.81.4-0.20.90.9-0.71.1-1.2
Indifference point function ln k0.00.10.20.00.10.1-0.30.4-0.5
Indifference point function log k0.00.10.20.00.10.1-0.30.4-0.5
Patch foraging total patch changes 0 sec0.51.31.5-1.11.11.1-1.21.2-1.1
Patch foraging total patch changes 12 sec3.74.95.8-2.42.32.3-2.22.1-2.0
Patch foraging total patch changes 18 sec0.10.20.7-0.80.50.5-0.50.2-0.1
Patch foraging total patch changes 24 sec0.51.72.9-1.71.51.4-1.21.1-1.0
Patch foraging total patch changes 6 sec0.71.21.7-1.31.21.2-1.10.9-0.8
Patch foraging time to switch 0 sec0.00.10.2-0.00.10.2-0.10.3-0.4
Patch foraging water rate 0 sec0.00.00.0-0.10.00.0-0.2-0.10.2
Patch foraging water rate 12 sec0.10.40.50.7-0.7-0.70.7-0.50.7
Patch foraging water rate 18 sec0.40.81.3-0.60.90.9-0.81.1-1.1
Patch foraging water rate 24 sec0.30.40.5-0.30.60.6-0.70.7-0.7
Patch foraging water rate 6 sec0.81.21.4-1.11.11.1-1.21.0-1.0
Seeking ratio, delayed vs. immediate footshock0.20.30.5-0.0-0.5-0.50.5-0.70.7
Distance traveled before self-admin0.10.10.20.5-0.5-0.50.5-0.10.1
Distance traveled after self-admin0.50.81.10.9-1.1-1.00.7-0.90.8
Extensor digitorum longus weight8.333.033.75.8-5.8-5.85.7-5.75.7
Bone: elastic displacement0.00.00.1-0.10.20.2-0.00.3-0.3
Bone: elastic work0.00.00.0-0.10.00.00.00.0-0.0
Bone: endosteal estimation1.53.84.52.1-2.1-2.11.8-1.81.8
Bone: endosteal perimeter1.53.74.52.1-2.1-2.01.8-1.81.8
Epididymis fat weight0.00.20.20.3-0.4-0.40.2-0.50.4
Delta time in closed arm before/after self-admin4.13.84.52.1-2.0-2.01.7-2.01.9
Delta time in open arm before/after self-admin0.00.00.10.00.10.10.10.2-0.1
Diff in mean of infusions in LGA sessions0.10.20.40.7-0.4-0.40.2-0.20.1
Delay discount exponential model param0.50.60.80.4-0.9-0.90.7-0.90.9
Extinction: sum of active levers before priming0.40.60.90.9-0.7-0.70.5-0.90.7
Active lever presses in extinction session 60.00.00.1-0.00.10.1-0.2-0.30.1
Bone: final force1.22.02.3-1.51.41.4-1.51.3-1.3
Bone: final moment1.11.71.9-1.41.31.3-1.41.3-1.3
Food consumed during 24 hour testing period0.51.01.30.9-1.1-1.10.8-1.11.1
Glucose0.50.81.1-1.00.90.9-0.80.8-0.8
Heart weight3.35.36.92.6-2.3-2.32.3-2.22.2
Delay discount hyperbolic model param0.50.60.70.4-0.8-0.90.7-0.80.9
Intermittent access intake day 1-15 change0.00.10.30.3-0.5-0.50.3-0.20.2
Intermittent access intake escalation0.00.10.20.4-0.5-0.40.2-0.20.1
Intermittent access intake escalation 20.40.70.90.7-0.9-0.90.7-0.90.9
Intermitt. access day 1 inactive lever presses0.00.61.2-0.40.60.7-0.71.1-1.0
Intermitt. access day 15 inactive lever presses0.10.81.0-1.01.01.0-0.70.8-0.7
Intermitt. access escalation Index0.41.41.91.1-1.1-1.11.0-1.31.4
Intermittent access day 1 total infusions0.00.00.10.20.00.00.00.2-0.3
Intermittent access day 15 total infusions0.00.10.20.5-0.4-0.40.2-0.0-0.0
Intermittent access terminal intake (last 3 days)0.00.00.1-0.1-0.0-0.0-0.20.2-0.3
Intermittent access total infusions0.10.10.10.3-0.3-0.30.3-0.1-0.0
Intermittent access day 1 locomotion0.10.20.4-0.10.40.4-0.40.6-0.6
Intermittent access day 15 total locomotion0.20.91.3-0.70.90.9-1.01.1-1.1
Intermittent access total locomotion1.31.62.2-1.01.21.2-1.21.5-1.5
Intermittent access standard deviation0.00.10.1-0.40.20.2-0.30.2-0.3
Left kidney weight0.75.86.62.3-2.4-2.42.3-2.62.4
Right kidney weight0.10.71.10.6-0.8-0.80.7-1.00.9
Cocaine induced anxiety1.85.05.72.4-2.3-2.32.1-2.22.2
Post-drug Anxiety0.91.01.51.2-1.1-1.00.9-0.90.9
Baseline Anxiety2.44.14.4-2.02.12.1-2.02.0-2.0
Tail length1.36.87.32.5-2.6-2.62.6-2.72.6
Length with tail4.821.322.54.7-4.6-4.74.4-4.74.6
Length without tail2.110.911.53.4-3.3-3.33.1-3.43.3
Times rat made contact with spout0.91.01.4-1.11.01.0-1.20.9-0.9
Lifetime Intake0.00.00.10.3-0.2-0.20.10.0-0.1
Liver weight, left0.20.30.50.4-0.5-0.50.6-0.70.6
Liver weight, right0.30.40.7-0.80.70.7-0.60.5-0.7
Locomotor activity0.50.80.9-0.91.00.9-1.00.7-0.8
Locomotor testing distance2.04.85.9-2.12.22.2-2.42.0-2.2
Locomotor testing rearing1.97.08.3-2.62.82.8-2.92.4-2.5
Locomotion in novel chamber2.73.64.8-2.02.22.1-1.81.6-1.5
Locomotion in novel chamber post-restriction0.10.30.5-0.70.40.4-0.60.4-0.5
Fecal boli incidents, locomotor time 10.10.30.50.6-0.5-0.50.7-0.70.6
Change in fecal boli incidents, locomotor task0.50.50.7-0.60.70.7-0.80.7-0.7
Time >=10cm from walls, locomotor time 10.81.01.5-0.90.90.9-0.71.2-1.2
Bouts of movement, locomotor time 10.40.50.90.8-0.7-0.70.9-0.50.4
Total resting periods, locomotor time 10.50.60.90.9-0.8-0.81.0-0.50.5
Rest time, locomotor task time 10.00.00.10.1-0.2-0.20.30.2-0.2
Distance moved, locomotor task time 10.10.10.3-0.50.30.4-0.60.2-0.2
Vertical activity count, locomotor time 10.00.10.40.6-0.2-0.20.2-0.10.1
Time >=10cm from walls, locomotor time 20.72.02.7-1.21.41.5-1.11.6-1.6
Bouts of movement, locomotor time 20.00.10.30.00.30.3-0.10.3-0.5
Total resting periods, locomotor time 20.00.00.10.30.00.10.20.2-0.4
Rest time, locomotor task time 20.81.32.01.2-1.2-1.11.4-0.90.9
Distance moved, locomotor task time 20.00.00.00.00.00.0-0.1-0.10.1
Vertical activity count, locomotor time 20.00.10.30.5-0.2-0.10.00.0-0.0
Light reinforcement 10.62.83.3-1.51.61.6-1.71.8-1.8
Light reinforcement 20.40.81.0-0.90.90.9-1.00.9-0.9
Bone: marrow area1.53.64.32.1-2.0-2.01.8-1.71.7
Bone: maximum diameter0.00.00.1-0.1-0.0-0.0-0.2-0.00.0
Bone: maximum force0.00.00.1-0.30.10.1-0.30.2-0.1
Bone: maximum moment0.00.00.0-0.20.00.0-0.20.2-0.1
Mean time between licks in bursts0.42.53.11.7-1.6-1.61.7-1.41.4
Mean num. licks in bursts0.00.00.00.10.00.0-0.0-0.00.0
Cd content in liver1.01.11.51.2-1.2-1.20.9-0.90.9
Co content in liver2.42.83.01.6-1.6-1.61.6-1.71.7
Cu content in liver0.81.01.30.8-1.0-1.01.1-1.11.1
Fe content in liver2.22.72.91.6-1.6-1.61.6-1.71.7
K content in liver0.00.00.1-0.20.10.10.10.1-0.0
Mg content in liver0.10.10.2-0.40.30.3-0.00.1-0.1
Mn content in liver0.00.00.1-0.20.20.2-0.20.2-0.2
Na content in liver0.10.10.2-0.50.40.4-0.30.3-0.3
Rb content in liver1.41.61.8-1.21.31.3-1.21.3-1.3
Se content in liver3.13.64.4-2.12.02.0-1.81.8-1.8
Sr content in liver1.21.01.01.0-1.0-1.01.0-1.01.0
Zn content in liver1.51.71.8-1.31.31.3-1.21.3-1.3
Bone: minimum diameter0.40.91.01.0-1.0-1.00.6-1.01.0
Time in familiar zone, hab. session 10.50.50.8-0.50.70.7-0.90.7-0.8
Time in novel zone, hab. session 10.60.70.9-1.00.80.8-0.60.8-0.8
Total zone transitions, hab. session 12.23.03.31.8-1.8-1.81.8-1.61.6
Total locomotion distance, hab. session 10.00.00.00.2-0.2-0.20.00.10.0
Locomotion velocity, hab. session 10.50.70.91.0-0.9-0.90.7-0.60.7
Time in familiar zone, hab. session 20.60.70.9-0.70.80.8-0.81.0-1.0
Time in novel zone, hab. session 20.00.00.0-0.20.20.1-0.10.1-0.1
Total zone transitions, hab. session 20.50.71.01.0-0.9-0.90.8-0.60.7
Total locomotion distance, hab. session 20.10.10.20.5-0.4-0.30.1-0.10.1
Locomotion velocity, hab. session 20.20.30.50.7-0.6-0.60.3-0.30.4
Novel to familiar place preference ratio1.31.72.21.3-1.3-1.31.3-1.51.4
Novelty place preference0.81.01.31.0-1.0-1.01.0-1.11.0
Time in novel zone, NPP test0.20.30.40.5-0.5-0.50.5-0.60.5
Total zone transitions, NPP test0.20.40.50.7-0.7-0.70.5-0.40.5
Total locomotion distance, NPP test0.00.00.1-0.00.00.0-0.10.3-0.2
Locomotion velocity, NPP test0.20.30.40.6-0.7-0.70.5-0.40.5
Intraocular pressure1.32.22.71.6-1.4-1.41.2-1.61.5
Delta distance traveled before/after self-admin0.50.60.70.8-0.8-0.80.5-0.90.8
Delta ambulatory time before/after self-admin0.10.20.40.6-0.5-0.50.1-0.60.5
Parametrial fat weight0.51.21.6-0.91.01.0-1.21.2-1.3
Pavlov. Cond. lever latency2.73.44.01.8-1.8-1.82.0-1.81.7
Pavlov. Cond. magazine entry latency9.412.113.4-3.63.63.6-3.73.3-3.2
Pavlov. Cond. change in total contacts8.38.910.2-3.23.13.1-3.12.6-2.6
Pavlov. Cond. index score9.111.512.9-3.43.53.5-3.63.2-3.2
Pavlov. Cond. latency score7.09.010.2-3.03.13.1-3.22.8-2.8
Pavlov. Cond. lever contacts3.44.14.6-2.02.02.0-2.12.0-1.9
Pavlov. Cond. magazine entry number13.717.318.64.3-4.3-4.34.3-3.93.9
Pavlov. Cond. intertrial magazine entries1.41.72.01.3-1.3-1.31.4-1.21.2
Pavlov. Cond. lever-magazine prob. diff.10.613.214.7-3.73.73.7-3.83.4-3.4
Pavlov. Cond. response bias10.413.014.2-3.73.73.7-3.83.4-3.4
Pavlov. Cond. lever latency0.30.40.60.6-0.6-0.60.8-0.50.5
Pavlov. Cond. magazine entry latency0.00.00.10.1-0.1-0.20.1-0.10.2
Pavlov. Cond. change in total contacts0.30.60.8-0.70.70.8-0.80.9-0.8
Pavlov. Cond. index score0.10.20.3-0.40.40.4-0.60.4-0.3
Pavlov. Cond. latency score0.10.20.3-0.40.40.4-0.60.3-0.2
Pavlov. Cond. lever contacts0.50.71.0-0.80.80.8-1.00.8-0.7
Pavlov. Cond. magazine entry number0.20.20.30.4-0.4-0.40.5-0.50.4
Pavlov. Cond. intertrial magazine entries1.02.22.31.5-1.5-1.51.5-1.51.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.30.30.3-0.40.3-0.2
Pavlov. Cond. response bias0.71.01.2-1.01.01.0-1.11.0-0.9
Time in closed arm before self-admin1.32.32.9-1.71.41.4-1.61.5-1.4
Time in closed arm after self-admin0.30.40.50.7-0.6-0.60.3-0.70.6
Time in open arm before self-admin2.73.23.51.8-1.7-1.71.9-1.91.8
Time in open arm after self-admin0.50.50.80.6-0.7-0.70.9-0.60.8
Bone: periosteal estimation0.10.30.40.6-0.6-0.60.4-0.50.5
Bone: periosteal perimeter0.51.11.31.1-1.1-1.10.8-1.01.0
Bone: post-yield work0.50.91.21.1-1.0-1.00.9-0.80.8
Progressive ratio test 1 active lever presses0.30.50.7-0.70.70.7-0.80.7-0.8
Progressive ratio test 1 breakpoint0.30.50.7-0.70.60.6-0.80.7-0.8
Progressive ratio test 1 inactive lever presses0.10.10.40.10.10.1-0.30.6-0.6
Progressive ratio test 2 active lever presses0.40.60.8-0.80.70.7-0.70.8-0.9
Progressive ratio test 2 breakpoint0.50.70.9-0.90.80.8-0.70.9-1.0
Progressive ratio test 2 inactive lever presses0.00.10.30.3-0.4-0.30.6-0.30.2
Incentive Sensitization - Responses0.30.70.9-1.00.80.8-0.70.9-1.0
Incentive Sensitization - Breakpoint0.20.50.7-0.90.70.7-0.50.7-0.8
Sum of active levers in priming session hrs 5-60.10.10.2-0.30.40.4-0.40.2-0.4
Progressive ratio0.00.00.10.0-0.1-0.2-0.0-0.00.3
Food seeking constrained by brief footshock0.50.60.9-0.80.70.7-0.70.9-0.8
Seeking ratio, punishment vs. effort0.10.30.5-0.50.50.6-0.40.5-0.7
Retroperitoneal fat weight0.10.71.1-0.70.60.7-0.90.9-1.0
Reaction time number correct0.31.01.41.2-1.1-1.11.0-0.80.9
Reaction time mean minus median0.00.10.10.3-0.2-0.20.1-0.20.2
Reaction time mean minus median AUC0.10.40.5-0.60.60.6-0.70.7-0.7
Reaction time num false alarms0.61.01.2-1.00.90.9-1.01.0-1.1
Reaction time num false alarms AUC0.30.70.9-0.90.80.8-0.80.8-1.0
Reaction time trials correct on left0.31.01.41.2-1.1-1.11.0-0.80.9
Reaction time trials on left0.30.91.31.2-1.0-1.00.9-0.80.8
Reaction time mean0.00.00.0-0.10.10.10.0-0.10.1
Reaction time mean AUC0.00.00.00.00.00.00.2-0.20.2
Median of all reaction times0.10.10.3-0.50.50.5-0.30.2-0.2
Reaction time omissions0.30.50.5-0.70.60.6-0.70.7-0.7
Reaction time false alarm rate1.31.82.2-1.51.31.3-1.31.3-1.4
Reaction time premature initiation rate0.30.50.7-0.70.60.6-0.80.7-0.7
Reaction time premature initiations0.00.00.10.3-0.3-0.30.0-0.10.1
Std. dev. reaction times0.00.00.0-0.10.10.1-0.20.0-0.1
Reaction time trials completed0.30.91.31.2-1.0-1.00.9-0.80.8
Reaction time trials AUC0.20.81.11.1-0.9-0.90.9-0.70.8
Run reversals in cocaine runway, females1.11.31.61.3-1.2-1.21.1-0.91.0
Run reversals in cocaine runway, males0.30.30.5-0.20.50.5-0.50.7-0.7
Latency to leave start box in cocaine runway2.33.13.91.6-1.8-1.82.0-1.81.6
Latency to leave start box in cocaine runway, F2.93.64.21.7-2.0-2.02.0-1.91.8
Latency to leave start box in cocaine runway, M0.40.40.70.5-0.5-0.50.8-0.70.5
Std. dev. time between licks in bursts0.20.40.50.6-0.6-0.60.7-0.70.7
Total sessions with >9 infusions0.00.00.10.10.00.1-0.20.2-0.3
Short access day 1 total inactive lever presses0.61.11.6-0.81.01.0-1.01.2-1.3
Short access day 10 total inactive lever presses0.10.60.80.8-0.9-0.90.8-0.60.6
Short access day 1 total infusions0.00.00.0-0.10.20.1-0.00.0-0.0
Short access day 10 total infusions0.10.20.2-0.30.50.5-0.40.4-0.5
Short access total infusions0.00.00.00.2-0.1-0.10.1-0.10.0
Short access day 1 locomotion0.40.70.7-0.80.80.8-0.90.8-0.8
Short access day 10 total locomotion0.93.74.4-1.71.91.9-2.11.9-1.9
Short access total locomotion0.20.30.4-0.30.50.5-0.60.7-0.6
One hour access (0.3 mA shock)0.00.00.10.1-0.1-0.1-0.10.1-0.3
Compulsive drug intake0.10.20.4-0.60.40.4-0.40.4-0.4
One hour access (shock baseline)0.00.10.30.5-0.4-0.40.2-0.20.1
Social response proportion0.10.10.2-0.00.10.10.20.5-0.3
Social responses0.10.10.4-0.20.30.3-0.10.6-0.5
Social time0.00.00.00.2-0.1-0.10.1-0.10.1
Soleus weight0.51.41.7-1.31.21.2-1.21.0-1.0
Bone: stiffness0.00.00.1-0.30.10.1-0.30.1-0.1
Tibialis anterior weight1.44.75.12.1-2.1-2.12.1-2.32.2
Time to tail flick, vehicle, before self-admin0.20.30.4-0.40.60.6-0.60.4-0.5
Time to tail flick, vehicle, after self-admin0.00.10.4-0.20.20.2-0.6-0.00.1
Time to tail flick, test, before self-admin0.30.30.40.6-0.6-0.60.5-0.50.5
Time to tail flick, test, after self-admin0.10.10.1-0.30.30.3-0.20.0-0.2
Delta time to tail flick, vehicle, before/after SA0.30.40.5-0.60.60.6-0.70.6-0.5
Delta time to tail flick, test, before/after SA1.51.82.1-1.31.41.4-1.31.2-1.3
Tibia length0.72.02.51.3-1.4-1.41.2-1.61.6
Ambulatory time before self-admin0.20.61.00.8-0.8-0.81.0-0.40.5
Ambulatory time after self-admin1.52.42.81.5-1.7-1.71.4-1.61.5
Bone: tissue strength0.40.50.70.5-0.6-0.70.7-0.80.8
Total heroin consumption0.30.30.5-0.60.70.7-0.50.2-0.5
Bone: trabecular number4.48.39.2-3.03.03.0-2.92.7-2.7
Bone: trabecular spacing0.81.21.51.2-1.1-1.11.1-0.90.9
Bone: trabecular thickness0.00.00.1-0.20.10.1-0.0-0.10.1
Bone: trabecular tissue density0.00.00.00.0-0.1-0.10.2-0.10.1
Water consumed over 24 hours0.00.00.0-0.0-0.1-0.1-0.20.1-0.0
Number of responses in last shaping day0.10.10.30.1-0.3-0.30.3-0.50.5