Hub : Genes

Fbxo42

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr5_158734430_158735406 0.06 0.04 6.4e-04 0.01 0.01 0.02 0.01 1.2e-02 2.3e-02 4.8e-03 2.0e-02
2 BLA mRNA stability Fbxo42 0.16 0.07 1.6e-06 0.06 0.09 0.09 0.07 5.7e-04 1.3e-05 2.3e-05 1.0e-04
3 pVTA mRNA stability Fbxo42 0.13 0.05 1.6e-10 0.13 0.15 0.13 0.14 1.5e-10 5.0e-12 9.7e-11 1.4e-11
4 Liver mRNA stability Fbxo42 0.31 0.1 0.0e+00 0.23 0.23 0.21 0.22 9.4e-25 5.8e-25 2.9e-23 8.8e-24
5 PL gene expression Fbxo42 0.49 0.1 0.0e+00 0.25 0.31 0.31 0.31 3.2e-27 1.3e-34 2.4e-34 6.4e-35
6 Liver gene expression Fbxo42 0.04 0.03 2.4e-03 0.02 0.02 0.01 0.01 2.1e-03 4.3e-03 6.8e-02 7.3e-03
7 Brain mRNA stability Fbxo42 0.12 0.05 4.0e-12 0.13 0.13 0.13 0.14 8.1e-12 3.0e-12 2.3e-12 1.4e-12
8 NAcc mRNA stability Fbxo42 0.2 0.07 0.0e+00 0.2 0.2 0.19 0.21 5.8e-30 1.7e-29 2.8e-28 9.2e-31
9 PL mRNA stability Fbxo42 0.16 0.06 3.3e-16 0.14 0.16 0.16 0.16 4.8e-15 2.2e-17 1.8e-17 4.0e-17
10 NAcc intron excision ratio chr5_158734430_158754882 0.13 0.05 0.0e+00 0.11 0.12 0.11 0.11 1.9e-16 1.9e-17 1.1e-16 7.4e-16
11 IC mRNA stability Fbxo42 0.22 0.11 5.3e-07 0.2 0.16 0.17 0.18 7.7e-09 2.0e-07 1.3e-07 5.3e-08
12 RMTg gene expression Fbxo42 0.22 0.12 6.7e-03 0.08 0.07 0.03 0.06 4.6e-03 5.4e-03 6.5e-02 1.1e-02
13 NAcc gene expression Fbxo42 0.28 0.08 0.0e+00 0.12 0.24 0.25 0.26 3.1e-18 1.6e-36 4.1e-38 1.2e-38
14 pVTA intron excision ratio chr5_158734430_158754882 0.14 0.06 3.5e-12 0.16 0.16 0.16 0.16 5.8e-13 7.2e-13 1.9e-12 1.3e-12
15 Adipose mRNA stability Fbxo42 0.2 0.09 0.0e+00 0.07 0.16 0.15 0.15 4.7e-08 4.5e-17 1.4e-16 1.1e-16
16 BLA gene expression Fbxo42 0.6 0.12 0.0e+00 0.27 0.38 0.36 0.4 2.1e-14 4.3e-21 5.7e-20 2.2e-22
17 Brain gene expression Fbxo42 0.35 0.1 0.0e+00 0.34 0.37 0.37 0.38 1.1e-32 7.0e-36 1.6e-36 1.0e-36
18 IL mRNA stability Fbxo42 0.29 0.16 6.6e-03 0.04 0 -0 0.01 3.5e-02 2.8e-01 4.1e-01 1.4e-01
19 pVTA gene expression Fbxo42 0.23 0.08 1.3e-13 0.15 0.19 0.18 0.19 4.7e-12 3.1e-15 2.7e-14 3.2e-15
20 Adipose gene expression Fbxo42 0.31 0.1 0.0e+00 0.22 0.26 0.26 0.26 3.2e-24 2.6e-29 2.0e-28 2.3e-29
21 IC gene expression Fbxo42 0.25 0.13 2.2e-04 0.03 0.08 0.05 0.05 3.0e-02 2.9e-04 4.0e-03 2.8e-03
22 IL gene expression Fbxo42 0.32 0.12 1.3e-05 0.07 0 0.11 0.08 8.8e-03 2.5e-01 1.2e-03 6.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.73.16.1-2.52.22.02.1-2.4-1.81.41.8-1.22.2-2.02.01.2-2.0-1.5-1.6-1.5-1.2-1.6-0.9-1.70.8
Area under the delay curve0.50.82.3-1.1-0.1-0.4-0.1-1.5-0.1-0.7-0.70.80.0-0.00.0-0.6-0.1-1.4-1.4-1.20.6-1.5-0.4-1.51.3
BMI with tail0.41.55.40.1-1.3-1.0-0.7-1.10.7-1.3-0.41.50.70.8-0.8-2.30.5-1.0-1.5-1.61.1-1.4-1.5-0.92.0
BMI without tail0.10.63.50.2-0.7-0.20.0-0.70.2-0.60.30.41.10.00.0-1.9-0.2-0.3-1.1-1.20.3-0.8-0.8-0.51.5
Body weight0.72.97.7-1.7-0.5-0.20.3-2.4-0.2-1.1-0.11.31.6-0.20.2-1.8-0.3-2.3-2.7-2.81.4-2.6-2.0-2.42.8
Weight adjusted by age0.31.03.40.7-0.6-0.10.2-1.20.4-0.7-0.00.91.40.9-0.9-1.50.5-0.9-1.5-1.60.4-1.3-0.7-0.61.9
Bone surface1.83.67.2-2.22.32.32.4-2.6-2.01.52.0-1.22.7-1.91.91.0-2.0-1.8-1.9-1.7-1.1-1.9-1.0-1.91.1
Bone volume1.73.37.1-2.42.32.02.1-2.7-1.71.31.7-1.02.3-1.91.91.3-1.9-2.0-1.9-1.7-1.1-1.9-1.2-1.81.0
Breakpoint value in progressive ratio session0.10.20.70.40.0-0.3-0.30.50.30.20.1-0.2-0.60.2-0.20.30.30.70.60.7-0.20.70.90.7-0.6
Number of licking bursts0.51.64.00.61.61.30.80.5-0.41.71.4-1.50.4-0.70.62.0-0.60.91.21.6-1.91.30.81.6-1.5
Context. condit. distance diff. score0.91.14.00.31.51.20.70.7-0.81.20.7-1.60.1-0.60.62.0-0.40.51.31.4-1.11.10.11.0-1.7
Locomotion velocity, session 11.92.15.91.40.6-0.0-0.61.70.70.7-0.3-0.7-1.40.9-0.92.31.11.22.12.3-0.72.11.12.3-2.4
Locomotion distance, session 11.01.33.30.30.4-0.3-0.71.40.60.2-0.7-0.4-1.70.5-0.61.70.71.21.61.8-0.31.81.41.7-1.8
Locomotion velocity, session 21.61.95.11.0-0.5-1.0-1.32.00.9-0.3-1.10.0-2.31.1-1.10.81.11.52.02.0-0.21.91.31.7-1.9
Locomotion distance, session 21.31.84.80.4-1.5-1.9-2.00.51.6-1.8-2.21.6-2.11.5-1.5-0.61.7-0.10.10.21.70.3-0.20.5-0.0
Locomotion velocity, session 30.30.31.0-0.30.30.2-0.10.8-0.00.30.0-0.6-0.4-0.10.10.4-0.10.80.90.9-0.61.00.40.9-0.8
Locomotion distance, session 30.30.41.20.40.50.50.20.7-0.20.40.1-0.8-0.1-0.40.51.1-0.30.30.90.9-0.80.80.10.8-1.0
Stereotopy head waving bouts, day 30.80.92.30.1-1.3-1.5-1.40.21.1-1.2-1.31.2-1.31.1-1.2-1.01.10.4-0.1-0.11.40.10.50.10.5
Stereotopy head waving duration, day 30.50.61.50.2-0.8-1.1-1.10.70.8-0.5-0.60.5-1.20.8-0.8-0.80.81.20.50.50.50.81.10.7-0.1
Locomotion velocity, session 71.21.33.40.31.31.71.50.6-1.31.31.4-1.81.3-1.31.30.5-1.30.50.80.8-1.60.6-0.30.5-0.9
Locomotion distance, session 70.50.61.80.71.21.31.10.0-0.70.90.7-1.21.0-0.80.80.9-0.7-0.10.30.5-0.90.2-0.10.4-0.6
Stereotopy head waving bouts, day 70.30.41.0-0.71.00.70.6-0.4-0.40.90.9-0.80.6-0.70.70.7-0.80.2-0.20.0-0.80.20.30.2-0.1
Stereotopy head waving duration, day 70.60.71.9-0.71.30.80.6-0.0-0.31.31.1-1.10.4-0.70.61.4-0.70.50.30.5-1.20.60.60.7-0.7
Locomotion velocity, session 80.91.12.71.4-0.8-1.1-1.41.01.0-1.1-1.60.6-1.61.1-1.10.61.20.10.91.00.30.8-0.51.0-1.0
Locomotion distance, session 80.20.42.6-0.71.20.70.3-0.2-0.50.4-0.1-0.7-0.0-0.30.31.6-0.2-0.40.20.5-0.10.3-0.50.3-0.8
Degree of sensitization distance0.20.21.01.0-0.4-0.20.0-0.30.3-0.3-0.10.40.30.6-0.6-1.00.5-0.1-0.4-0.30.8-0.4-0.1-0.10.6
Degree of sensitization stereotypy0.91.02.1-1.21.51.31.3-0.9-1.11.21.4-1.11.3-1.31.30.7-1.3-0.1-0.6-0.4-1.0-0.30.0-0.30.2
Conditioned locomotion0.50.51.7-1.0-0.5-0.3-0.21.2-0.7-0.3-0.70.0-1.3-0.40.4-0.6-0.41.30.80.60.20.91.3-0.3-0.4
Cocaine response after cond. corrected2.84.211.22.7-3.3-2.7-2.40.32.6-2.6-2.02.7-1.02.2-2.2-3.32.2-0.1-0.8-0.82.4-0.5-0.70.31.6
Cocaine response after cond. not corrected1.42.18.12.2-2.5-1.8-1.60.41.7-1.8-1.11.8-0.51.4-1.4-2.91.30.3-0.5-0.51.5-0.2-0.00.31.3
Cocaine response before conditioning2.22.75.7-1.12.42.01.70.5-1.52.31.9-2.30.7-1.51.52.3-1.51.11.21.3-2.21.11.60.7-1.6
Saline control response1.21.75.5-2.31.41.51.8-0.8-1.91.21.5-0.91.3-1.71.7-0.2-1.80.0-0.6-0.8-0.7-0.70.7-1.50.6
Bone: connectivity density1.83.06.7-2.22.22.22.3-2.2-1.71.72.3-1.42.6-1.71.70.8-1.7-1.0-1.6-1.4-1.1-1.3-0.4-1.31.0
Bone: cortical apparent density1.01.54.50.10.30.40.22.1-0.21.10.7-1.1-0.6-0.00.00.5-0.02.12.01.8-0.91.82.11.4-1.6
Bone: cortical area2.23.67.9-2.82.82.62.5-1.7-2.42.02.2-1.92.1-2.22.22.0-2.1-0.9-1.0-0.7-1.4-0.9-0.2-1.30.1
Bone: cortical porosity0.30.32.3-0.7-0.5-0.6-0.40.2-0.1-0.6-0.70.5-1.0-0.10.2-0.1-0.20.7-0.2-0.10.40.21.5-0.40.3
Bone: cortical porosity1.11.22.90.4-1.5-1.7-1.40.21.1-1.6-1.71.6-1.60.9-0.9-0.61.00.3-0.3-0.21.50.00.9-0.10.5
Bone: cortical thickness3.15.211.0-3.33.23.02.9-0.6-3.02.83.0-2.81.8-2.82.92.2-2.70.70.10.3-2.30.31.2-0.7-0.7
Bone: cortical thickness1.92.44.8-2.12.12.02.1-1.2-2.21.51.4-1.51.6-2.12.11.3-2.1-0.6-0.7-0.4-1.1-0.7-0.1-1.40.1
Bone: cortical tissue density0.91.54.60.50.20.30.12.1-0.11.00.6-1.0-0.60.1-0.10.30.12.12.01.8-0.81.82.11.5-1.5
Condit. Reinf. active minus inactive responses0.50.61.60.5-0.1-0.4-0.60.90.90.3-0.30.0-0.90.4-0.40.90.30.81.01.1-0.51.01.01.2-1.0
Condit. Reinf. active-inactive response ratio0.30.31.1-0.0-0.3-0.7-0.80.31.0-0.1-0.40.5-0.70.7-0.70.20.60.30.20.30.40.40.70.8-0.2
Condit. Reinf. active responses0.91.23.20.70.40.0-0.31.40.50.80.2-0.7-0.90.1-0.11.40.11.31.61.8-1.41.61.31.7-1.7
Condit. Reinf. inactive responses0.40.51.50.80.30.40.21.0-0.10.50.4-0.8-0.2-0.00.00.7-0.00.81.11.2-1.21.00.40.9-1.1
Incentive salience index mean0.81.13.00.10.4-0.1-0.51.20.70.8-0.0-0.5-1.10.4-0.41.70.41.11.41.6-0.91.41.41.6-1.6
Condit. Reinf. lever presses0.91.45.4-0.41.10.70.31.10.01.40.8-1.2-0.5-0.10.12.3-0.01.01.51.5-1.61.41.31.5-1.9
Condit. Reinf. active minus inactive responses0.20.30.7-0.60.00.20.3-0.6-0.3-0.20.10.00.7-0.40.4-0.6-0.3-0.6-0.8-0.80.3-0.7-0.7-0.60.7
Condit. Reinf. active-inactive response ratio0.10.10.80.8-0.6-0.5-0.40.10.5-0.4-0.20.3-0.10.1-0.1-0.90.10.3-0.1-0.00.20.1-0.10.30.3
Condit. Reinf. active responses0.40.51.6-1.30.70.70.8-0.8-1.00.20.1-0.30.6-0.90.80.4-0.8-0.9-0.6-0.8-0.1-0.8-0.6-1.10.3
Condit. Reinf. inactive responses0.71.04.6-2.11.51.11.2-0.7-1.40.80.4-0.80.4-1.01.01.6-1.0-0.7-0.3-0.4-0.5-0.60.3-1.1-0.2
Condit. Reinf. lever presses0.30.51.2-0.81.10.90.8-1.1-0.60.50.3-0.50.9-0.50.50.8-0.6-1.1-0.7-0.5-0.3-0.7-0.5-0.50.2
Condit. Reinf. lever reinforcers received0.60.82.0-1.20.60.70.8-1.2-1.0-0.10.1-0.10.9-0.90.90.1-0.8-1.3-1.0-1.20.1-1.2-1.0-1.40.8
Conditioned reinforcement - actives0.00.20.7-0.10.30.10.00.10.20.60.6-0.30.0-0.20.2-0.0-0.30.60.20.4-0.80.40.80.6-0.3
Conditioned reinforcement - inactives0.10.31.70.2-0.9-0.8-0.80.00.8-0.7-0.40.8-0.40.5-0.5-1.30.50.1-0.3-0.10.3-0.1-0.10.20.5
Conditioned locomotion0.10.20.70.6-0.0-0.4-0.50.10.70.10.10.2-0.30.7-0.7-0.30.50.50.10.4-0.10.40.80.7-0.1
Patch foraging indifference point 0 sec1.44.014.3-3.82.22.42.50.0-2.92.32.3-2.31.3-2.62.50.3-2.51.60.20.2-1.60.62.3-0.8-0.3
Patch foraging indifference point AUC1.63.89.6-0.83.13.02.7-1.0-2.02.62.5-2.52.3-2.12.12.6-2.1-0.50.00.4-2.4-0.10.1-0.1-0.9
Delay disc. indifference point, 0s delay0.40.41.30.0-0.0-0.8-0.8-0.60.4-0.6-1.20.8-1.00.7-0.70.90.6-1.0-0.30.00.9-0.5-0.6-0.3-0.1
Delay disc. indifference point, 16s delay0.50.71.9-0.8-0.2-0.6-0.4-1.20.2-0.8-0.70.9-0.10.1-0.1-0.50.1-1.4-1.2-1.00.7-1.3-0.6-1.31.1
Delay disc. indifference point, 2s delay0.91.03.2-1.40.00.00.4-1.6-0.7-0.5-0.40.60.6-0.40.4-0.8-0.3-1.3-1.6-1.50.6-1.6-0.5-1.81.6
Delay disc. indifference point, 24s delay0.20.31.2-1.1-0.0-0.10.2-0.5-0.4-0.3-0.10.2-0.1-0.80.8-0.5-0.8-0.2-0.6-0.40.2-0.60.5-1.00.7
Delay disc. indifference point, 4s delay0.80.82.2-0.6-0.6-0.7-0.4-1.20.2-1.0-0.71.0-0.10.6-0.6-1.00.5-1.0-1.4-1.40.7-1.2-0.5-1.21.5
Delay disc. indifference point, 8s delay0.61.01.9-0.2-0.7-1.2-0.9-1.20.8-1.2-1.21.4-0.50.7-0.7-0.80.6-1.3-1.2-0.91.3-1.2-0.6-0.91.2
Indifference point function ln k1.75.211.81.5-3.2-3.4-3.31.42.6-2.9-3.02.8-3.02.8-2.8-1.82.80.60.40.12.70.60.30.80.3
Indifference point function log k1.75.211.81.5-3.2-3.4-3.31.42.6-2.9-3.02.8-3.02.8-2.8-1.82.80.60.40.12.70.60.30.80.3
Patch foraging total patch changes 0 sec1.23.513.3-3.62.12.32.30.1-2.72.22.2-2.21.1-2.42.40.3-2.31.50.20.3-1.50.72.3-0.7-0.3
Patch foraging total patch changes 12 sec5.47.314.9-3.53.93.73.5-1.0-3.33.53.4-3.42.4-3.43.42.4-3.40.40.00.4-3.10.21.3-0.8-0.9
Patch foraging total patch changes 18 sec5.914.028.8-4.45.15.45.2-0.4-5.04.94.8-4.93.2-4.54.53.0-4.41.50.81.2-4.20.72.5-1.0-1.6
Patch foraging total patch changes 24 sec2.48.317.6-3.74.14.24.2-2.2-3.73.43.6-3.13.4-3.63.62.0-3.4-0.5-1.1-0.6-2.3-0.80.8-1.60.1
Patch foraging total patch changes 6 sec4.57.716.0-3.53.84.03.9-1.2-3.53.53.7-3.33.0-3.43.41.7-3.40.5-0.4-0.1-2.8-0.11.6-1.0-0.3
Patch foraging time to switch 0 sec0.00.11.30.1-0.8-0.3-0.10.4-0.1-0.4-0.20.1-0.0-0.10.1-1.2-0.20.30.0-0.2-0.0-0.10.0-0.30.4
Patch foraging water rate 0 sec0.41.74.2-0.72.01.71.4-0.1-1.02.11.8-1.60.8-1.01.02.0-1.00.80.51.0-1.50.91.30.8-1.1
Patch foraging water rate 12 sec0.10.21.1-1.00.80.40.4-1.0-0.30.60.6-0.00.4-0.10.10.5-0.2-0.3-0.7-0.3-0.1-0.20.1-0.20.3
Patch foraging water rate 18 sec0.51.13.20.6-0.7-1.3-1.4-0.61.8-0.8-0.91.2-0.81.7-1.70.51.6-0.5-0.5-0.21.3-0.0-0.20.80.2
Patch foraging water rate 24 sec0.20.31.31.2-0.5-0.5-0.60.40.7-0.5-0.30.4-0.50.8-0.80.30.70.40.30.50.40.50.50.7-0.2
Patch foraging water rate 6 sec0.40.61.7-1.31.10.90.9-0.9-0.80.91.1-0.50.7-0.90.90.7-0.90.1-0.6-0.4-0.3-0.20.7-0.30.3
Seeking ratio, delayed vs. immediate footshock0.50.72.30.7-0.2-0.6-0.7-0.91.2-0.6-0.50.90.21.1-1.10.20.6-1.3-0.8-0.80.6-0.8-1.50.10.5
Distance traveled before self-admin1.12.46.1-0.62.52.01.6-0.1-1.42.52.2-2.31.2-1.41.42.0-1.60.60.81.1-2.20.80.50.8-1.4
Distance traveled after self-admin1.22.24.6-0.81.51.61.31.1-1.32.01.9-2.00.6-1.11.10.9-1.21.81.41.5-2.21.41.91.0-1.3
Extensor digitorum longus weight0.00.20.7-0.80.70.40.3-0.5-0.00.50.6-0.40.50.1-0.10.60.0-0.3-0.2-0.0-0.3-0.1-0.20.2-0.0
Bone: elastic displacement1.82.34.9-0.71.82.01.90.7-2.01.91.9-2.20.9-1.71.70.6-1.71.70.91.0-1.71.02.20.1-0.9
Bone: elastic work2.33.16.3-1.32.42.52.5-0.1-2.42.32.2-2.41.4-2.22.21.1-2.21.00.50.5-1.80.41.8-0.5-0.7
Bone: endosteal estimation1.53.710.90.6-1.0-0.9-0.7-2.61.3-1.8-1.42.11.11.3-1.3-1.21.1-3.2-2.6-2.52.1-2.6-3.3-1.32.4
Bone: endosteal perimeter0.82.05.30.5-1.2-1.3-1.2-1.41.3-1.8-1.51.8-0.01.3-1.3-0.81.3-2.1-1.5-1.51.8-1.5-2.3-0.71.4
Epididymis fat weight0.41.94.80.4-1.3-1.6-1.5-1.21.4-1.7-1.51.8-0.41.3-1.3-1.21.3-1.6-1.5-1.41.6-1.2-2.2-0.41.3
Delta time in closed arm before/after self-admin4.44.110.60.6-1.6-1.8-1.6-2.11.5-2.5-2.32.7-0.21.4-1.4-1.11.5-3.1-2.3-2.32.4-2.4-3.3-1.52.1
Delta time in open arm before/after self-admin2.52.95.62.1-1.6-1.7-2.02.41.9-0.8-1.30.7-2.22.0-2.00.22.11.62.01.80.61.90.92.1-1.5
Diff in mean of infusions in LGA sessions0.10.20.40.00.10.50.6-0.2-0.60.20.3-0.30.6-0.60.6-0.4-0.5-0.2-0.2-0.2-0.5-0.4-0.1-0.50.3
Delay discount exponential model param0.81.03.01.20.10.40.01.70.20.80.6-0.9-0.20.2-0.20.90.21.41.71.4-0.71.70.61.7-1.6
Extinction: sum of active levers before priming1.31.96.30.9-0.8-1.5-1.61.11.5-0.5-1.10.9-2.31.7-1.70.51.71.50.91.30.61.42.51.4-0.8
Active lever presses in extinction session 61.81.83.61.9-1.8-1.8-1.80.91.8-1.5-1.81.4-1.71.7-1.7-0.51.50.30.50.61.30.50.50.8-0.2
Bone: final force2.03.26.0-2.42.32.32.4-2.1-2.21.61.9-1.52.3-2.02.11.0-2.0-1.2-1.4-1.3-0.9-1.4-0.5-1.70.7
Bone: final moment1.62.54.9-2.02.22.12.2-1.9-2.01.41.7-1.42.0-1.81.81.1-1.7-1.2-1.2-1.1-0.8-1.2-0.6-1.40.5
Food consumed during 24 hour testing period0.40.72.6-0.70.10.00.1-1.50.2-0.30.10.60.90.1-0.1-0.40.1-1.5-1.3-1.30.6-1.3-1.6-0.81.0
Glucose0.00.10.2-0.10.20.20.3-0.3-0.40.30.5-0.20.40.00.0-0.2-0.10.1-0.3-0.1-0.1-0.10.2-0.10.2
Heart weight1.32.05.7-1.32.11.81.8-1.9-0.92.02.4-1.32.1-1.11.11.2-1.3-0.7-1.1-0.8-1.4-0.90.3-0.50.5
Delay discount hyperbolic model param0.91.13.51.30.20.40.01.70.30.90.7-0.9-0.20.2-0.20.90.21.51.71.5-0.71.70.61.9-1.6
Intermittent access intake day 1-15 change0.00.30.9-0.90.00.50.6-0.0-0.60.30.7-0.40.9-0.40.4-0.9-0.50.5-0.2-0.3-0.6-0.0-0.1-0.10.5
Intermittent access intake escalation0.00.10.8-0.6-0.20.30.30.1-0.30.10.5-0.20.6-0.20.2-0.9-0.20.5-0.1-0.3-0.40.0-0.20.00.5
Intermittent access intake escalation 20.00.00.2-0.3-0.30.0-0.00.30.0-0.10.0-0.00.20.1-0.1-0.40.20.40.10.1-0.10.30.00.30.1
Intermitt. access day 1 inactive lever presses0.00.10.5-0.00.0-0.2-0.30.60.10.1-0.1-0.1-0.5-0.20.20.5-0.00.40.70.6-0.20.60.00.6-0.7
Intermitt. access day 15 inactive lever presses0.00.10.40.1-0.2-0.3-0.4-0.10.6-0.3-0.50.4-0.20.5-0.50.10.7-0.4-0.10.00.5-0.2-0.50.2-0.0
Intermitt. access escalation Index0.20.71.4-0.11.11.11.2-0.1-1.21.11.1-1.10.6-1.01.00.6-1.10.40.10.1-1.00.01.1-0.4-0.3
Intermittent access day 1 total infusions0.51.63.51.9-1.3-1.5-1.61.41.9-0.8-1.10.9-1.71.3-1.3-0.21.30.71.21.30.71.00.81.4-0.9
Intermittent access day 15 total infusions0.51.23.01.4-1.7-1.4-1.50.91.7-1.1-0.91.1-0.91.4-1.4-1.21.20.50.50.60.70.5-0.11.10.0
Intermittent access terminal intake (last 3 days)0.61.02.31.2-1.3-1.0-1.21.51.5-0.6-0.60.6-0.91.1-1.1-0.60.90.91.21.20.21.00.31.5-0.7
Intermittent access total infusions2.32.86.02.5-2.0-2.0-2.21.92.4-1.3-1.31.3-1.82.0-2.0-0.81.81.11.51.50.81.30.61.9-0.9
Intermittent access day 1 locomotion0.40.72.61.6-1.0-0.9-1.01.11.0-0.6-0.70.6-0.90.9-0.9-0.50.90.60.80.80.50.70.40.9-0.5
Intermittent access day 15 total locomotion0.10.51.90.4-1.1-0.9-0.8-0.00.9-0.8-0.50.9-0.20.9-0.9-1.40.8-0.1-0.4-0.40.6-0.2-0.30.10.7
Intermittent access total locomotion0.40.52.21.0-1.1-0.6-0.51.10.6-0.4-0.10.3-0.30.7-0.7-1.50.51.10.60.50.10.60.80.60.0
Intermittent access standard deviation0.20.82.81.0-0.5-0.9-1.21.11.2-0.2-0.40.2-1.10.9-0.90.50.90.71.11.1-0.01.2-0.21.7-1.1
Left kidney weight0.32.26.7-2.21.91.31.4-2.6-0.71.11.4-0.41.9-0.80.91.2-1.0-2.0-1.9-1.7-0.8-1.8-0.7-1.41.1
Right kidney weight0.21.55.4-1.71.20.70.8-2.3-0.30.40.60.11.4-0.40.40.7-0.5-2.0-1.8-1.70.0-1.7-1.0-1.31.2
Cocaine induced anxiety0.71.93.7-1.51.81.91.9-0.6-1.71.81.9-1.71.6-1.71.60.8-1.80.3-0.2-0.2-1.7-0.10.7-0.5-0.1
Post-drug Anxiety3.13.58.1-2.82.62.62.5-1.4-1.92.42.5-2.12.4-2.02.01.5-2.2-0.4-0.7-0.5-2.2-0.50.1-0.60.1
Baseline Anxiety0.40.71.9-1.41.21.11.0-0.3-0.61.21.0-1.00.8-0.60.71.4-0.6-0.40.10.1-1.1-0.0-0.40.0-0.5
Tail length0.10.71.8-0.30.10.50.7-1.1-0.5-0.3-0.00.21.0-0.50.6-0.2-0.5-1.3-1.1-1.20.5-1.3-1.0-1.31.0
Length with tail0.62.57.5-2.00.10.51.0-2.2-1.0-0.6-0.10.71.5-0.90.9-0.8-0.8-2.2-2.3-2.41.1-2.4-1.4-2.72.1
Length without tail0.63.29.3-2.1-0.5-0.10.5-2.4-0.8-1.2-0.51.51.3-0.50.5-1.7-0.6-2.4-2.7-2.81.5-2.8-1.7-3.02.8
Times rat made contact with spout0.30.32.9-0.40.80.1-0.1-0.30.20.60.0-0.2-0.60.3-0.31.70.5-0.10.40.7-0.10.40.40.6-0.8
Lifetime Intake2.73.48.42.9-2.0-1.9-2.22.42.5-1.2-1.31.1-2.12.0-2.0-0.31.91.42.02.00.71.70.72.3-1.4
Liver weight, left1.11.94.5-0.2-0.4-1.3-1.3-1.71.7-1.3-1.31.7-0.41.9-1.90.41.8-2.1-1.5-1.31.5-1.4-1.7-0.31.0
Liver weight, right1.01.74.00.7-1.6-1.6-1.4-0.31.2-1.8-1.61.8-0.61.6-1.6-1.51.5-1.0-0.8-1.02.0-0.9-1.2-0.51.1
Locomotor activity2.13.310.8-3.32.82.32.1-1.6-2.02.42.7-2.01.8-1.91.91.4-1.90.1-0.8-0.5-1.9-0.20.5-0.60.1
Locomotor testing distance1.43.58.7-1.72.52.01.60.5-1.22.92.8-2.40.6-1.21.12.2-1.12.01.21.6-2.51.72.51.4-1.6
Locomotor testing rearing0.93.58.2-0.52.41.71.20.9-0.82.92.5-2.40.3-0.70.62.7-0.62.11.72.0-2.42.12.32.0-2.2
Locomotion in novel chamber1.31.83.9-1.81.11.41.8-1.5-1.90.71.0-0.81.5-1.71.7-0.3-1.5-0.7-1.3-1.2-0.6-1.30.1-2.01.2
Locomotion in novel chamber post-restriction0.51.62.8-1.61.61.41.5-1.7-1.41.21.4-1.01.6-1.51.40.7-1.4-0.9-1.2-0.9-1.0-1.0-0.5-1.10.7
Fecal boli incidents, locomotor time 10.40.92.9-1.2-0.20.30.6-1.1-0.6-0.20.60.21.3-0.60.6-1.6-0.8-0.5-1.4-1.60.3-1.1-0.8-1.31.7
Change in fecal boli incidents, locomotor task0.50.62.21.5-0.9-1.0-1.00.31.1-0.7-0.80.7-0.90.9-0.9-0.60.90.2-0.00.20.40.20.60.50.0
Time >=10cm from walls, locomotor time 10.81.03.4-1.80.71.21.20.0-1.50.81.2-1.11.3-1.31.3-0.3-1.50.2-0.1-0.4-1.1-0.2-0.5-0.70.3
Bouts of movement, locomotor time 10.81.03.2-0.7-0.50.40.9-0.7-0.9-0.40.50.01.4-1.01.0-1.8-0.9-0.4-1.1-1.3-0.1-1.3-0.3-1.61.7
Total resting periods, locomotor time 11.21.43.4-0.6-0.30.71.3-0.8-1.2-0.30.7-0.21.8-1.31.3-1.8-1.2-0.4-1.2-1.5-0.2-1.4-0.2-1.81.9
Rest time, locomotor task time 10.40.72.20.6-0.00.71.0-0.3-1.00.00.7-0.31.5-1.01.0-1.4-1.2-0.1-0.7-0.9-0.1-0.8-0.3-1.01.1
Distance moved, locomotor task time 10.51.35.4-1.51.20.4-0.10.7-0.11.20.3-0.9-1.2-0.00.02.30.30.91.31.5-1.01.51.31.3-1.9
Vertical activity count, locomotor time 10.21.55.8-1.11.00.2-0.41.00.31.10.2-0.7-1.30.3-0.32.40.61.11.61.9-1.11.71.31.8-2.1
Time >=10cm from walls, locomotor time 20.41.15.10.2-0.20.40.22.3-0.70.40.3-0.9-0.2-0.80.7-0.4-0.81.91.81.4-1.21.40.80.8-1.0
Bouts of movement, locomotor time 20.10.41.6-0.9-0.40.10.4-0.1-0.6-0.40.10.10.4-0.60.5-1.3-0.50.1-0.4-0.40.6-0.60.7-1.21.1
Total resting periods, locomotor time 20.10.41.3-1.00.10.40.7-0.3-0.80.00.5-0.30.7-0.80.7-0.9-0.80.1-0.4-0.30.3-0.60.8-1.10.9
Rest time, locomotor task time 20.71.23.3-0.40.81.21.5-1.3-1.20.71.4-0.81.8-1.21.2-0.4-1.6-0.3-1.2-1.1-0.2-1.00.1-1.11.1
Distance moved, locomotor task time 20.20.31.2-1.10.70.60.50.2-0.70.60.3-0.60.1-0.70.70.6-0.10.30.40.3-0.70.40.10.0-0.5
Vertical activity count, locomotor time 20.40.81.7-1.20.80.50.21.0-0.31.00.5-0.9-0.4-0.50.51.3-0.21.11.21.2-1.21.20.81.0-1.3
Light reinforcement 10.62.57.0-1.92.62.32.1-1.5-1.72.32.4-1.81.9-1.41.41.8-1.3-0.2-0.7-0.2-1.7-0.30.5-0.4-0.2
Light reinforcement 20.10.20.90.90.10.1-0.20.60.40.20.2-0.10.10.4-0.50.30.50.20.50.6-0.40.5-0.20.9-0.5
Bone: marrow area1.53.711.00.6-1.0-1.0-0.7-2.61.3-1.8-1.42.11.11.2-1.2-1.31.1-3.2-2.6-2.52.2-2.7-3.3-1.42.4
Bone: maximum diameter0.40.92.5-1.41.30.90.8-1.6-0.60.50.5-0.20.9-0.60.61.6-0.6-1.4-1.1-0.9-0.1-1.0-0.8-0.80.4
Bone: maximum force1.42.85.4-2.32.32.22.2-2.0-1.91.61.9-1.42.3-1.81.81.1-1.7-1.3-1.3-1.2-0.8-1.2-0.7-1.40.6
Bone: maximum moment1.12.14.5-1.92.11.91.9-1.9-1.61.31.6-1.21.9-1.51.51.1-1.4-1.2-1.2-1.0-0.6-1.1-0.9-1.10.4
Mean time between licks in bursts0.00.20.6-0.20.0-0.4-0.4-0.60.4-0.3-0.50.4-0.30.5-0.50.50.4-0.8-0.3-0.20.3-0.4-0.4-0.20.0
Mean num. licks in bursts0.30.93.1-0.6-1.0-1.1-0.8-0.40.5-1.2-1.31.3-0.80.8-0.8-0.90.9-0.7-0.8-1.01.8-0.9-0.3-1.00.8
Cd content in liver1.41.65.6-0.8-0.40.50.8-0.8-1.4-0.60.60.11.5-1.51.5-2.4-1.5-0.5-1.5-1.70.1-1.3-1.2-1.71.9
Co content in liver0.10.20.4-0.60.60.30.1-0.0-0.20.70.5-0.6-0.00.1-0.10.60.00.20.40.4-0.70.3-0.30.3-0.6
Cu content in liver1.51.89.9-3.21.01.31.4-0.0-2.01.21.4-1.60.7-2.02.0-0.2-1.90.90.0-0.2-1.30.20.5-0.9-0.0
Fe content in liver0.20.32.60.20.90.50.3-0.60.30.70.2-0.30.30.2-0.21.60.2-0.80.10.2-0.1-0.2-0.30.4-0.6
K content in liver0.20.20.6-0.6-0.3-0.4-0.50.70.1-0.3-0.50.1-0.80.1-0.20.00.10.40.60.3-0.00.60.10.3-0.5
Mg content in liver0.30.43.5-1.90.30.30.40.0-0.80.30.5-0.5-0.0-0.90.9-0.1-0.90.5-0.0-0.1-0.30.20.5-0.40.1
Mn content in liver0.70.82.2-1.2-0.0-0.10.0-1.40.1-0.5-0.00.50.8-0.10.1-0.5-0.1-1.3-1.5-1.40.5-1.2-1.4-0.91.2
Na content in liver0.50.62.7-1.60.90.40.4-1.4-0.40.2-0.20.20.2-0.10.11.1-0.1-1.4-0.8-0.80.4-0.9-0.6-0.80.3
Rb content in liver0.40.41.10.9-1.0-0.7-0.61.00.4-0.5-0.50.2-0.80.4-0.5-1.00.40.90.70.60.10.70.40.5-0.3
Se content in liver0.70.81.9-1.0-1.2-1.1-0.9-0.50.3-1.3-1.01.4-0.60.4-0.4-1.00.4-0.6-0.9-1.11.3-0.8-0.6-1.11.1
Sr content in liver0.30.30.8-0.40.1-0.0-0.1-0.60.4-0.2-0.10.50.30.9-0.90.00.9-0.7-0.7-0.50.5-0.4-0.4-0.00.5
Zn content in liver0.80.95.6-2.40.50.50.7-1.0-1.10.20.7-0.30.8-1.21.1-0.6-1.2-0.4-1.1-1.2-0.4-0.7-0.4-1.11.1
Bone: minimum diameter1.01.85.6-0.70.10.30.5-2.2-0.4-0.60.00.81.6-0.20.2-0.6-0.2-2.4-2.0-2.00.9-2.2-2.3-1.71.7
Time in familiar zone, hab. session 12.02.24.3-2.11.91.81.9-0.9-1.91.82.0-1.61.4-2.02.01.0-2.00.1-0.5-0.4-1.8-0.30.4-0.80.0
Time in novel zone, hab. session 10.80.92.80.9-1.0-0.7-0.81.70.6-0.6-0.80.3-1.00.7-0.7-1.10.81.31.21.00.61.11.00.9-0.6
Total zone transitions, hab. session 10.20.31.9-0.10.80.40.30.1-0.20.4-0.1-0.5-0.4-0.40.41.4-0.10.00.40.7-0.60.40.70.3-0.8
Total locomotion distance, hab. session 10.10.21.70.40.60.20.2-0.5-0.2-0.1-0.6-0.0-0.3-0.10.11.30.1-0.9-0.10.20.1-0.3-0.2-0.2-0.4
Locomotion velocity, hab. session 10.30.42.80.50.5-0.1-0.1-0.80.3-0.4-0.90.4-0.50.3-0.31.70.6-1.3-0.4-0.00.5-0.5-0.4-0.3-0.3
Time in familiar zone, hab. session 21.31.54.1-0.41.01.41.30.8-1.21.71.9-1.70.7-1.11.20.7-1.11.41.00.9-2.00.91.20.4-1.0
Time in novel zone, hab. session 20.50.62.20.6-0.8-0.9-0.9-0.10.8-1.1-1.21.1-0.60.7-0.7-1.00.6-0.4-0.4-0.31.5-0.2-0.3-0.00.6
Total zone transitions, hab. session 20.50.71.61.2-0.6-0.8-1.00.71.3-0.6-0.90.6-0.91.0-1.0-0.11.30.40.50.70.60.70.31.2-0.4
Total locomotion distance, hab. session 20.10.20.50.3-0.1-0.4-0.5-0.00.5-0.6-0.70.4-0.50.5-0.5-0.00.6-0.1-0.00.20.70.20.10.4-0.0
Locomotion velocity, hab. session 20.20.20.70.1-0.1-0.4-0.5-0.40.6-0.6-0.80.6-0.40.5-0.50.20.7-0.5-0.3-0.10.8-0.1-0.10.20.1
Novel to familiar place preference ratio1.82.38.32.9-2.4-1.7-1.71.91.4-1.8-1.71.3-1.11.5-1.5-2.11.50.71.10.51.40.7-0.20.9-0.1
Novelty place preference1.52.07.22.7-2.2-1.5-1.51.61.3-1.7-1.61.3-0.91.4-1.4-2.11.50.50.80.41.40.4-0.50.70.0
Time in novel zone, NPP test1.41.77.02.7-2.0-1.3-1.31.91.1-1.4-1.41.0-0.91.3-1.3-1.91.30.81.10.71.10.7-0.20.9-0.2
Total zone transitions, NPP test0.81.22.9-0.40.90.30.01.4-0.40.6-0.3-0.9-1.3-0.40.41.7-0.31.31.51.7-1.01.61.71.0-1.7
Total locomotion distance, NPP test0.20.30.8-0.50.80.50.50.3-0.70.1-0.2-0.6-0.4-0.60.60.8-0.50.40.40.6-0.30.50.9-0.1-0.6
Locomotion velocity, NPP test0.10.20.5-0.60.40.30.3-0.3-0.7-0.4-0.6-0.1-0.3-0.50.50.4-0.4-0.3-0.3-0.10.3-0.20.3-0.70.1
Intraocular pressure0.71.14.8-0.0-0.1-0.10.0-1.80.5-0.5-0.30.61.10.8-0.8-0.50.9-1.8-1.5-1.40.8-1.5-2.2-0.61.2
Delta distance traveled before/after self-admin0.50.52.50.6-1.4-0.5-0.31.10.4-0.6-0.30.5-0.10.6-0.6-1.60.60.90.40.30.20.31.10.20.4
Delta ambulatory time before/after self-admin0.71.24.71.2-2.1-1.3-1.11.31.0-1.4-1.01.1-0.61.2-1.2-2.21.20.70.40.10.80.30.30.30.5
Parametrial fat weight0.71.74.01.3-1.5-1.7-1.70.51.7-1.3-1.51.5-1.62.0-2.0-0.31.90.00.20.41.40.20.40.7-0.1
Pavlov. Cond. lever latency0.20.32.10.4-0.5-0.10.10.7-0.30.00.5-0.30.1-0.10.1-1.4-0.11.30.20.20.40.51.00.00.4
Pavlov. Cond. magazine entry latency0.50.62.5-0.40.4-0.1-0.1-1.60.8-0.0-0.30.80.40.6-0.61.00.5-1.6-1.2-0.80.8-1.1-0.7-0.20.6
Pavlov. Cond. change in total contacts0.50.62.8-0.0-0.1-0.2-0.1-1.20.4-0.6-0.71.00.30.4-0.40.20.3-1.7-1.0-0.80.5-1.2-1.1-0.70.7
Pavlov. Cond. index score0.40.53.4-0.30.90.20.0-1.10.60.3-0.20.30.20.4-0.41.90.3-1.5-0.5-0.2-0.1-0.6-0.70.2-0.2
Pavlov. Cond. latency score0.40.42.6-0.50.70.1-0.0-1.20.40.0-0.30.50.20.3-0.31.50.2-1.6-0.7-0.40.1-0.8-1.0-0.20.0
Pavlov. Cond. lever contacts0.30.42.2-0.20.3-0.3-0.5-0.30.7-0.3-0.90.6-0.70.6-0.61.50.6-1.00.10.20.0-0.2-0.40.2-0.6
Pavlov. Cond. magazine entry number0.91.15.00.8-1.0-0.5-0.62.2-0.2-0.2-0.0-0.5-1.1-0.10.1-1.3-0.02.11.61.2-0.71.51.00.7-0.8
Pavlov. Cond. intertrial magazine entries3.03.612.21.2-0.6-0.5-0.83.50.10.3-0.3-1.1-2.20.1-0.10.20.13.43.12.8-1.33.03.02.0-2.4
Pavlov. Cond. lever-magazine prob. diff.0.30.43.3-0.20.80.1-0.1-0.90.70.3-0.30.30.00.5-0.51.80.4-1.2-0.30.0-0.1-0.4-0.50.3-0.4
Pavlov. Cond. response bias0.50.65.0-0.21.20.50.3-1.40.50.5-0.10.10.40.4-0.42.20.3-1.7-0.6-0.20.0-0.7-0.60.2-0.3
Pavlov. Cond. lever latency0.60.92.11.5-1.0-1.1-1.1-0.31.2-0.9-0.91.2-0.51.3-1.3-0.21.4-0.6-0.3-0.31.1-0.3-0.90.30.3
Pavlov. Cond. magazine entry latency0.50.71.90.7-1.4-1.3-1.20.81.1-1.2-1.11.0-1.10.9-0.9-0.60.80.20.40.10.40.10.20.20.0
Pavlov. Cond. change in total contacts0.30.71.6-0.80.20.60.7-1.0-0.6-0.10.4-0.01.3-0.80.8-0.8-0.9-0.9-1.1-1.1-0.4-1.1-0.7-1.11.1
Pavlov. Cond. index score0.10.20.9-1.00.20.40.5-0.0-0.60.00.3-0.30.4-0.80.7-0.3-0.8-0.1-0.2-0.3-0.5-0.30.1-0.60.3
Pavlov. Cond. latency score0.10.20.6-0.7-0.10.20.40.0-0.5-0.20.2-0.10.4-0.70.7-0.6-0.8-0.1-0.2-0.4-0.4-0.3-0.0-0.70.4
Pavlov. Cond. lever contacts0.50.72.0-1.41.01.11.00.2-1.10.90.8-1.10.4-1.11.10.5-1.20.50.20.3-0.90.30.9-0.2-0.4
Pavlov. Cond. magazine entry number0.00.10.20.30.30.30.3-0.4-0.30.20.2-0.10.5-0.00.0-0.20.1-0.1-0.3-0.20.4-0.1-0.1-0.10.3
Pavlov. Cond. intertrial magazine entries0.20.41.3-0.90.90.70.8-0.7-0.50.91.1-0.80.8-0.30.30.5-0.10.3-0.5-0.2-0.4-0.00.5-0.00.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-0.90.20.50.6-0.1-0.60.10.4-0.40.6-0.80.8-0.3-0.9-0.1-0.2-0.3-0.6-0.30.0-0.60.3
Pavlov. Cond. response bias0.20.21.4-1.20.50.50.40.1-0.50.30.2-0.5-0.0-0.70.70.4-0.70.10.10.1-0.50.10.5-0.3-0.3
Time in closed arm before self-admin2.23.77.5-1.21.92.21.91.5-1.42.72.5-2.70.8-1.41.31.5-1.42.31.92.0-2.51.92.71.3-1.9
Time in closed arm after self-admin0.20.20.80.5-0.4-0.2-0.1-0.20.1-0.5-0.50.50.20.4-0.4-0.30.5-0.9-0.2-0.30.4-0.6-0.9-0.50.2
Time in open arm before self-admin3.94.712.0-0.3-0.6-0.50.1-3.40.0-1.7-1.01.91.50.1-0.1-1.5-0.1-3.4-3.5-3.51.8-3.4-3.3-2.83.1
Time in open arm after self-admin1.11.22.51.3-1.1-1.4-1.51.11.5-0.8-1.00.8-1.61.4-1.40.01.40.90.70.70.71.00.61.3-0.5
Bone: periosteal estimation0.92.27.4-1.21.00.91.0-2.7-0.5-0.00.40.31.9-0.40.50.4-0.5-2.7-2.2-2.10.6-2.2-2.3-1.61.6
Bone: periosteal perimeter0.81.64.4-1.61.11.01.1-2.1-0.80.30.8-0.21.7-0.70.70.6-0.8-1.9-1.8-1.6-0.1-1.6-1.7-1.31.1
Bone: post-yield work0.71.22.90.4-0.9-1.2-1.3-0.31.6-1.2-1.21.3-0.61.6-1.5-0.31.6-0.9-0.6-0.51.7-0.4-1.10.50.4
Progressive ratio test 1 active lever presses0.81.43.11.8-1.6-1.5-1.60.81.7-1.3-1.31.3-1.11.4-1.4-0.91.40.00.40.61.20.3-0.10.8-0.1
Progressive ratio test 1 breakpoint0.61.02.71.6-1.4-1.3-1.30.61.6-1.1-1.11.2-0.91.3-1.3-0.81.2-0.00.30.51.00.2-0.10.70.0
Progressive ratio test 1 inactive lever presses0.10.31.00.9-0.4-0.4-0.51.00.5-0.1-0.10.1-0.50.3-0.30.00.30.60.90.8-0.20.70.10.8-0.8
Progressive ratio test 2 active lever presses0.40.51.31.1-0.8-0.7-0.80.91.1-0.3-0.20.5-0.50.7-0.7-0.60.60.80.71.0-0.10.70.61.1-0.3
Progressive ratio test 2 breakpoint0.40.51.11.1-0.8-0.6-0.70.91.0-0.3-0.20.4-0.40.7-0.7-0.60.50.80.60.9-0.10.70.51.0-0.3
Progressive ratio test 2 inactive lever presses0.00.10.5-0.6-0.4-0.2-0.30.30.40.00.30.1-0.1-0.10.1-0.7-0.20.50.20.3-0.40.30.20.40.0
Incentive Sensitization - Responses0.20.41.20.6-0.8-0.5-0.51.10.7-0.3-0.20.3-0.70.3-0.3-0.60.31.00.81.0-0.10.81.00.8-0.4
Incentive Sensitization - Breakpoint0.20.41.20.4-0.8-0.4-0.41.10.5-0.2-0.10.2-0.60.2-0.2-0.60.21.10.81.0-0.20.81.10.7-0.4
Sum of active levers in priming session hrs 5-60.30.30.80.1-0.6-0.4-0.1-0.40.1-0.7-0.60.7-0.10.1-0.1-0.60.10.0-0.7-0.60.7-0.50.8-0.70.9
Progressive ratio0.20.71.5-1.20.81.01.0-0.8-1.10.40.5-0.61.0-1.11.20.5-1.0-0.6-0.5-0.6-0.6-0.7-0.5-0.80.3
Food seeking constrained by brief footshock0.40.51.9-1.40.60.70.70.2-0.80.70.8-1.00.4-0.90.90.2-0.90.80.2-0.0-0.80.41.00.0-0.2
Seeking ratio, punishment vs. effort0.30.61.20.7-0.6-0.7-0.81.10.8-0.2-0.30.3-1.10.8-0.9-0.30.81.00.90.90.31.01.00.9-0.7
Retroperitoneal fat weight0.10.51.60.5-0.3-0.2-0.1-0.90.3-0.4-0.10.60.80.6-0.6-0.70.5-1.0-1.1-0.80.6-0.9-1.3-0.31.0
Reaction time number correct0.41.53.60.9-0.1-0.4-0.81.70.90.3-0.3-0.2-1.41.1-1.11.21.21.51.81.9-0.51.81.51.9-1.8
Reaction time mean minus median0.00.21.1-0.30.20.50.5-0.4-0.10.20.6-0.51.0-0.10.0-0.2-0.2-0.1-0.4-0.6-0.5-0.3-0.2-0.10.6
Reaction time mean minus median AUC0.21.45.3-0.90.71.41.5-1.3-1.10.61.4-0.92.3-1.21.2-0.6-1.2-0.8-1.2-1.3-1.0-1.2-1.0-1.01.3
Reaction time num false alarms0.50.82.10.40.2-0.5-0.70.71.00.50.00.0-1.11.0-1.01.11.00.81.01.3-0.31.11.31.4-1.2
Reaction time num false alarms AUC0.51.12.50.9-0.0-0.8-1.10.91.30.2-0.30.3-1.41.2-1.21.11.20.81.11.4-0.11.21.21.6-1.2
Reaction time trials correct on left0.41.53.60.9-0.1-0.4-0.81.70.90.3-0.3-0.2-1.41.1-1.11.21.21.51.81.9-0.51.81.51.9-1.8
Reaction time trials on left0.51.63.60.9-0.2-0.5-0.81.70.90.2-0.4-0.2-1.51.1-1.11.21.31.41.81.9-0.41.81.41.9-1.8
Reaction time mean0.40.82.40.8-1.4-1.0-0.90.01.0-1.3-0.81.1-0.01.0-1.0-1.60.9-0.4-0.4-0.81.0-0.5-1.0-0.01.0
Reaction time mean AUC0.71.63.61.2-1.8-1.5-1.3-0.11.4-1.8-1.31.5-0.21.4-1.4-1.91.4-0.6-0.7-0.91.4-0.7-1.2-0.11.3
Median of all reaction times1.32.14.31.5-2.1-1.9-1.80.11.7-2.0-1.71.9-0.71.6-1.7-1.91.6-0.6-0.5-0.81.7-0.5-1.30.11.1
Reaction time omissions0.91.42.50.9-1.5-1.6-1.4-0.51.3-1.6-1.21.5-0.61.4-1.5-1.11.4-0.7-1.0-1.01.2-0.7-1.0-0.21.2
Reaction time false alarm rate0.20.30.80.6-0.4-0.8-0.90.10.9-0.3-0.40.6-0.70.8-0.80.10.70.00.10.30.50.20.20.5-0.1
Reaction time premature initiation rate0.91.55.8-0.50.40.60.51.8-0.80.90.7-1.2-0.7-0.60.70.6-0.52.21.71.6-1.41.72.40.7-1.3
Reaction time premature initiations0.82.38.5-0.30.50.60.42.3-0.61.10.7-1.4-1.0-0.40.41.1-0.32.62.22.1-1.62.22.91.3-1.9
Std. dev. reaction times0.00.10.7-0.2-0.00.30.4-0.0-0.20.10.5-0.40.8-0.10.1-0.5-0.20.1-0.2-0.5-0.5-0.2-0.1-0.10.5
Reaction time trials completed0.51.63.60.9-0.2-0.5-0.81.70.90.2-0.4-0.2-1.51.1-1.11.21.31.41.81.9-0.41.81.41.9-1.8
Reaction time trials AUC0.41.43.40.70.0-0.3-0.71.50.80.3-0.3-0.3-1.41.0-1.01.41.21.31.71.8-0.51.81.41.9-1.8
Run reversals in cocaine runway, females1.21.32.9-1.31.31.21.20.2-1.61.31.5-1.70.6-1.61.50.5-1.71.10.40.0-1.50.60.8-0.2-0.5
Run reversals in cocaine runway, males0.40.41.10.7-0.4-0.3-0.4-0.41.0-0.4-0.20.60.41.0-1.0-0.20.7-0.9-0.4-0.50.5-0.5-1.00.30.4
Latency to leave start box in cocaine runway0.30.41.3-0.0-0.0-0.5-0.6-0.70.7-0.3-0.90.8-0.60.6-0.71.20.6-1.1-0.30.10.7-0.5-0.5-0.2-0.1
Latency to leave start box in cocaine runway, F0.40.52.5-0.60.3-0.0-0.0-1.30.4-0.1-0.40.60.30.5-0.60.90.5-1.6-1.0-0.50.4-1.1-0.7-0.70.5
Latency to leave start box in cocaine runway, M0.80.73.00.7-0.7-1.1-1.20.90.8-0.6-1.20.8-1.70.7-0.70.60.60.30.90.80.70.70.30.7-0.9
Std. dev. time between licks in bursts2.34.38.5-2.32.82.92.8-1.0-2.82.32.5-2.52.3-2.92.91.1-2.9-0.1-0.2-0.1-2.5-0.30.0-0.9-0.3
Total sessions with >9 infusions0.60.82.81.7-1.1-0.9-1.01.21.1-0.6-0.70.6-0.90.9-0.9-0.20.80.51.01.00.50.7-0.11.0-0.7
Short access day 1 total inactive lever presses0.91.74.62.0-0.5-0.9-1.31.71.40.0-0.40.1-1.51.0-1.00.81.01.21.82.0-0.21.70.72.1-1.7
Short access day 10 total inactive lever presses0.00.10.6-0.50.3-0.1-0.3-0.2-0.10.10.0-0.1-0.2-0.20.20.3-0.1-0.1-0.1-0.2-0.10.1-0.80.2-0.2
Short access day 1 total infusions1.22.57.02.6-1.7-1.9-2.11.52.1-1.4-1.71.4-2.01.9-1.9-0.11.70.41.21.11.20.9-0.11.5-0.9
Short access day 10 total infusions3.25.213.23.6-2.9-2.9-3.12.13.2-2.3-2.52.3-2.52.9-2.9-0.72.80.41.51.41.91.1-0.32.1-0.9
Short access total infusions2.63.710.33.2-2.1-2.1-2.42.22.5-1.4-1.71.4-2.32.2-2.20.02.10.91.91.81.11.50.22.1-1.5
Short access day 1 locomotion0.10.20.50.5-0.10.30.30.7-0.50.30.3-0.40.2-0.40.4-0.3-0.60.60.50.3-0.20.30.00.0-0.3
Short access day 10 total locomotion0.21.03.71.9-1.3-1.2-1.20.61.3-1.0-0.81.0-0.71.4-1.4-1.11.30.30.30.40.70.30.00.80.1
Short access total locomotion0.60.83.92.0-1.3-1.1-1.10.91.0-1.0-0.70.8-0.71.1-1.1-1.21.00.50.50.30.70.4-0.20.60.0
One hour access (0.3 mA shock)1.31.53.91.1-0.9-1.0-1.31.91.5-0.1-0.30.1-1.41.0-1.0-0.11.01.61.71.7-0.11.71.22.0-1.4
Compulsive drug intake0.40.61.7-1.10.80.80.9-1.3-0.70.60.8-0.31.0-0.70.70.0-0.7-0.6-1.0-0.9-0.4-0.8-0.2-0.80.8
One hour access (shock baseline)0.51.43.21.4-0.9-1.0-1.31.71.5-0.3-0.60.3-1.31.1-1.10.21.11.11.51.50.11.40.51.8-1.3
Social response proportion0.60.83.7-1.0-0.6-0.10.4-0.6-0.6-0.60.10.30.7-0.50.5-1.9-0.5-0.1-1.1-1.50.6-1.00.0-1.41.6
Social responses1.11.45.5-2.41.31.41.6-0.3-1.61.31.7-1.41.1-1.31.40.1-1.20.8-0.3-0.4-1.20.01.2-0.60.3
Social time0.71.22.60.5-1.6-1.6-1.40.01.2-1.5-1.01.5-1.01.2-1.2-1.61.20.1-0.5-0.61.3-0.30.4-0.11.0
Soleus weight0.30.85.20.31.30.4-0.0-1.10.90.60.0-0.20.41.1-1.12.31.0-1.4-0.30.2-0.2-0.2-0.91.0-0.6
Bone: stiffness1.32.48.5-2.00.60.10.3-2.8-0.1-0.5-0.20.81.1-0.10.10.4-0.0-2.9-2.3-2.31.1-2.3-2.6-1.81.6
Tibialis anterior weight0.10.31.2-0.90.90.50.3-0.7-0.10.50.4-0.30.5-0.00.01.10.0-0.7-0.4-0.3-0.4-0.3-0.5-0.0-0.0
Time to tail flick, vehicle, before self-admin0.50.72.21.5-0.6-0.9-1.00.81.1-0.4-0.70.4-0.91.1-1.10.30.90.30.80.60.10.7-0.31.2-0.7
Time to tail flick, vehicle, after self-admin0.71.44.50.5-1.0-0.50.0-1.3-0.0-1.2-0.51.20.9-0.20.2-2.1-0.1-1.1-1.7-1.81.4-1.7-1.3-1.52.0
Time to tail flick, test, before self-admin1.82.15.40.20.60.50.12.2-0.21.30.7-1.3-0.9-0.10.11.7-0.12.12.32.3-1.32.12.01.7-2.2
Time to tail flick, test, after self-admin0.60.61.50.4-0.3-1.0-1.0-0.61.0-0.7-1.20.9-1.00.8-0.90.90.9-1.0-0.5-0.31.2-0.4-0.4-0.1-0.0
Delta time to tail flick, vehicle, before/after SA1.61.75.0-0.1-1.4-1.1-0.6-1.10.2-1.8-1.31.7-0.10.1-0.1-2.20.3-1.1-1.6-1.62.1-1.5-0.7-1.72.0
Delta time to tail flick, test, before/after SA1.72.15.9-0.4-0.5-1.0-0.8-2.20.8-1.4-1.31.60.00.6-0.5-0.60.6-2.4-2.1-2.01.7-1.9-2.1-1.41.6
Tibia length1.44.011.5-1.00.30.41.0-3.4-0.6-0.8-0.11.22.2-0.70.7-0.6-0.6-3.4-3.2-3.31.1-3.4-2.3-2.92.7
Ambulatory time before self-admin1.03.07.0-0.62.62.11.70.1-1.52.72.3-2.51.0-1.71.62.3-1.80.91.01.4-2.31.11.10.9-1.6
Ambulatory time after self-admin1.11.75.50.00.50.90.71.6-0.61.41.5-1.50.1-0.70.7-0.0-0.82.31.61.7-1.71.72.31.3-1.1
Bone: tissue strength0.60.61.60.8-1.0-0.9-0.8-0.20.6-1.3-1.01.0-0.30.7-0.7-1.00.6-0.5-0.6-0.61.2-0.5-0.7-0.40.8
Total heroin consumption0.30.41.9-0.5-0.1-0.8-0.80.10.7-0.3-0.90.5-1.40.7-0.70.50.90.10.20.40.60.30.90.3-0.4
Bone: trabecular number1.12.04.7-2.21.81.81.8-1.8-1.51.31.8-1.21.9-1.51.50.7-1.5-0.9-1.2-1.2-1.2-1.1-0.4-1.10.6
Bone: trabecular spacing0.71.02.71.4-0.8-1.2-1.40.61.4-0.6-1.00.9-1.21.5-1.5-0.01.60.20.40.71.00.60.21.1-0.4
Bone: trabecular thickness1.92.65.2-2.32.22.02.0-1.5-1.91.51.7-1.61.7-2.12.11.3-2.2-1.0-0.8-0.8-1.6-1.0-0.5-1.40.2
Bone: trabecular tissue density0.30.51.4-0.20.40.20.11.0-0.40.60.2-0.7-0.7-0.20.21.0-0.41.01.20.9-1.10.90.80.4-1.2
Water consumed over 24 hours0.30.53.2-0.10.80.1-0.3-0.20.90.90.4-0.1-0.30.8-0.81.80.8-0.10.50.8-0.40.50.31.2-0.9
Number of responses in last shaping day0.40.51.10.6-0.8-1.0-1.00.00.7-1.0-1.00.9-0.70.8-0.8-0.40.8-0.6-0.2-0.11.1-0.2-1.0-0.00.2