Hub : Genes

Fbxo42

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr5_158734430_158735406 0.06 0.04 6.4e-04 0.01 0.01 0.02 0.01 1.2e-02 2.3e-02 4.8e-03 1.9e-02
2 BLA mRNA stability Fbxo42 0.16 0.07 1.6e-06 0.06 0.09 0.09 0.07 5.7e-04 1.3e-05 2.3e-05 9.9e-05
3 pVTA mRNA stability Fbxo42 0.13 0.05 1.6e-10 0.13 0.15 0.13 0.14 1.5e-10 5.0e-12 9.7e-11 1.4e-11
4 Liver mRNA stability Fbxo42 0.31 0.1 0.0e+00 0.23 0.23 0.21 0.22 9.4e-25 5.8e-25 2.7e-23 9.9e-24
5 PL gene expression Fbxo42 0.49 0.1 0.0e+00 0.25 0.31 0.31 0.31 3.2e-27 1.3e-34 2.5e-34 6.7e-35
6 Liver gene expression Fbxo42 0.04 0.03 2.4e-03 0.02 0.02 0.01 0.01 2.1e-03 4.3e-03 6.8e-02 7.3e-03
7 Brain mRNA stability Fbxo42 0.12 0.05 4.0e-12 0.13 0.13 0.13 0.14 8.1e-12 3.0e-12 2.2e-12 1.4e-12
8 NAcc mRNA stability Fbxo42 0.2 0.07 0.0e+00 0.2 0.2 0.19 0.21 5.8e-30 1.7e-29 2.6e-28 9.1e-31
9 PL mRNA stability Fbxo42 0.16 0.06 3.3e-16 0.14 0.16 0.16 0.16 4.8e-15 2.2e-17 1.8e-17 4.1e-17
10 NAcc intron excision ratio chr5_158734430_158754882 0.13 0.05 0.0e+00 0.11 0.12 0.11 0.11 1.9e-16 1.9e-17 1.1e-16 6.7e-16
11 IC mRNA stability Fbxo42 0.22 0.11 5.3e-07 0.2 0.16 0.17 0.18 7.7e-09 2.0e-07 1.3e-07 5.5e-08
12 RMTg gene expression Fbxo42 0.22 0.12 6.7e-03 0.08 0.07 0.03 0.06 4.6e-03 5.4e-03 6.5e-02 1.1e-02
13 NAcc gene expression Fbxo42 0.28 0.08 0.0e+00 0.12 0.24 0.25 0.26 3.1e-18 1.6e-36 4.0e-38 1.2e-38
14 pVTA intron excision ratio chr5_158734430_158754882 0.14 0.06 3.5e-12 0.16 0.16 0.16 0.16 5.8e-13 7.2e-13 1.9e-12 1.2e-12
15 Adipose mRNA stability Fbxo42 0.2 0.09 0.0e+00 0.07 0.16 0.15 0.15 4.7e-08 4.5e-17 1.4e-16 1.1e-16
16 BLA gene expression Fbxo42 0.6 0.12 0.0e+00 0.27 0.38 0.36 0.4 2.1e-14 4.3e-21 5.6e-20 2.1e-22
17 Brain gene expression Fbxo42 0.35 0.1 0.0e+00 0.34 0.37 0.37 0.38 1.1e-32 7.0e-36 1.6e-36 1.1e-36
18 IL mRNA stability Fbxo42 0.29 0.16 6.6e-03 0.04 0 -0 0.01 3.5e-02 2.8e-01 4.1e-01 1.4e-01
19 pVTA gene expression Fbxo42 0.23 0.08 1.3e-13 0.15 0.19 0.18 0.19 4.7e-12 3.1e-15 2.7e-14 3.1e-15
20 Adipose gene expression Fbxo42 0.31 0.1 0.0e+00 0.22 0.26 0.26 0.26 3.2e-24 2.6e-29 2.0e-28 2.4e-29
21 IC gene expression Fbxo42 0.25 0.13 2.2e-04 0.03 0.08 0.05 0.06 3.0e-02 2.9e-04 4.2e-03 2.6e-03
22 IL gene expression Fbxo42 0.32 0.12 1.3e-05 0.07 0 0.11 0.08 8.8e-03 2.5e-01 1.1e-03 6.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.83.16.12.52.22.02.1-2.41.81.41.81.22.22.0-2.01.22.0-1.5-1.6-1.51.2-1.6-0.9-1.7-0.8
Area under the delay curve0.70.82.31.1-0.1-0.4-0.1-1.50.1-0.7-0.7-0.80.00.0-0.0-0.60.1-1.4-1.4-1.2-0.6-1.5-0.4-1.5-1.3
BMI with tail0.41.55.4-0.1-1.3-1.0-0.7-1.1-0.7-1.3-0.4-1.50.7-0.80.8-2.3-0.5-1.0-1.5-1.6-1.1-1.4-1.5-0.9-2.0
BMI without tail0.20.63.5-0.2-0.7-0.20.0-0.7-0.2-0.60.3-0.41.1-0.0-0.0-1.90.2-0.3-1.1-1.2-0.3-0.8-0.8-0.5-1.5
Body weight0.72.97.71.7-0.5-0.20.3-2.40.2-1.1-0.1-1.31.60.2-0.2-1.80.3-2.3-2.7-2.8-1.4-2.6-2.0-2.4-2.8
Weight adjusted by age0.61.03.4-0.7-0.6-0.10.2-1.2-0.4-0.7-0.0-0.91.4-0.90.9-1.5-0.5-0.9-1.5-1.6-0.4-1.3-0.7-0.6-1.9
Bone surface2.03.67.22.22.32.32.4-2.62.01.52.01.22.71.9-1.91.02.0-1.8-1.9-1.71.1-1.9-1.0-1.9-1.1
Bone volume1.93.37.22.42.32.02.1-2.71.71.31.71.02.31.9-1.91.31.9-2.0-1.9-1.71.1-1.9-1.2-1.8-1.0
Breakpoint value in progressive ratio session0.20.20.7-0.40.0-0.3-0.30.5-0.30.20.10.2-0.6-0.20.20.3-0.30.70.60.70.20.70.90.70.6
Number of licking bursts1.01.54.0-0.61.61.30.80.40.41.71.41.50.40.7-0.62.00.60.91.21.61.91.30.81.61.5
Context. condit. distance diff. score0.91.14.0-0.31.51.20.70.70.81.20.71.60.10.6-0.62.00.40.51.31.41.11.10.11.01.7
Locomotion velocity, session 11.92.15.9-1.40.6-0.0-0.61.7-0.70.7-0.30.7-1.4-0.90.92.3-1.11.22.12.30.72.11.12.32.4
Locomotion distance, session 11.11.33.3-0.30.4-0.3-0.71.4-0.60.2-0.70.4-1.7-0.50.61.7-0.71.21.61.80.31.81.41.71.8
Locomotion velocity, session 21.61.95.1-1.0-0.5-1.0-1.32.0-0.9-0.3-1.1-0.0-2.3-1.11.10.8-1.11.52.02.00.21.91.31.71.9
Locomotion distance, session 21.31.84.8-0.4-1.5-1.9-2.00.5-1.6-1.8-2.2-1.6-2.1-1.51.5-0.6-1.7-0.10.10.2-1.70.3-0.20.50.0
Locomotion velocity, session 30.30.31.00.30.30.2-0.10.80.00.30.00.6-0.40.1-0.10.40.10.80.90.90.61.00.40.90.8
Locomotion distance, session 30.40.41.2-0.40.50.50.20.70.20.40.10.8-0.10.4-0.51.10.30.30.90.90.80.80.10.81.0
Stereotopy head waving bouts, day 30.80.92.3-0.1-1.3-1.5-1.40.2-1.1-1.2-1.3-1.2-1.3-1.11.2-1.0-1.10.4-0.1-0.1-1.40.10.50.1-0.5
Stereotopy head waving duration, day 30.50.61.5-0.2-0.8-1.1-1.10.7-0.8-0.5-0.6-0.5-1.2-0.80.8-0.8-0.81.20.50.5-0.50.81.10.70.1
Locomotion velocity, session 71.21.33.4-0.31.31.71.50.61.31.31.41.81.31.3-1.30.51.30.50.80.81.60.6-0.30.50.9
Locomotion distance, session 70.50.61.8-0.71.21.31.10.00.70.90.71.21.00.8-0.80.90.7-0.10.30.50.90.2-0.10.40.6
Stereotopy head waving bouts, day 70.30.41.00.71.00.70.6-0.40.40.90.90.80.60.7-0.70.70.80.2-0.20.00.80.20.30.20.1
Stereotopy head waving duration, day 70.60.71.90.71.30.80.6-0.00.31.31.11.10.40.7-0.61.40.70.50.30.51.20.60.60.70.7
Locomotion velocity, session 80.91.12.7-1.4-0.8-1.1-1.41.0-1.0-1.1-1.6-0.6-1.6-1.11.10.6-1.20.10.91.0-0.30.8-0.51.01.0
Locomotion distance, session 80.20.42.60.71.20.70.3-0.20.50.4-0.10.7-0.00.3-0.31.60.2-0.40.20.50.10.3-0.50.30.8
Degree of sensitization distance0.20.21.0-1.0-0.4-0.20.0-0.3-0.3-0.3-0.1-0.40.3-0.60.6-1.0-0.5-0.1-0.4-0.3-0.8-0.4-0.1-0.1-0.6
Degree of sensitization stereotypy1.01.02.11.21.51.31.3-0.91.11.21.41.11.31.3-1.30.71.3-0.1-0.6-0.41.0-0.30.0-0.3-0.2
Conditioned locomotion0.50.51.71.0-0.5-0.3-0.21.20.7-0.3-0.7-0.0-1.30.4-0.4-0.60.41.30.80.6-0.20.91.3-0.30.4
Cocaine response after cond. corrected3.54.211.2-2.7-3.3-2.7-2.40.3-2.6-2.6-2.0-2.7-1.0-2.22.2-3.3-2.2-0.1-0.8-0.8-2.4-0.5-0.70.3-1.6
Cocaine response after cond. not corrected1.82.18.1-2.2-2.5-1.8-1.60.5-1.7-1.8-1.1-1.8-0.5-1.41.4-2.9-1.30.3-0.5-0.5-1.5-0.2-0.00.3-1.3
Cocaine response before conditioning2.32.75.71.12.42.01.70.51.52.31.92.30.71.5-1.52.31.51.11.21.32.21.11.60.71.6
Saline control response1.31.75.52.31.41.51.8-0.81.91.21.50.91.31.7-1.7-0.21.80.0-0.6-0.80.7-0.70.7-1.5-0.6
Bone: connectivity density1.93.06.72.22.22.22.3-2.21.71.72.31.32.61.7-1.70.81.7-1.0-1.7-1.41.1-1.3-0.4-1.3-1.0
Bone: cortical apparent density1.11.54.5-0.10.30.40.22.10.21.10.71.1-0.60.0-0.00.50.02.12.01.80.91.82.11.41.6
Bone: cortical area2.43.67.92.82.82.62.5-1.82.42.02.21.92.12.2-2.22.02.1-0.9-1.0-0.71.4-0.9-0.2-1.3-0.1
Bone: cortical porosity0.30.32.30.7-0.5-0.6-0.40.20.1-0.6-0.7-0.5-1.00.1-0.2-0.10.20.7-0.2-0.1-0.40.21.5-0.4-0.3
Bone: cortical porosity1.11.22.9-0.4-1.5-1.7-1.40.2-1.1-1.6-1.7-1.6-1.6-0.90.9-0.6-1.00.3-0.3-0.2-1.50.00.9-0.1-0.5
Bone: cortical thickness3.15.211.03.33.23.02.9-0.63.02.83.02.81.82.8-2.92.22.70.70.10.32.30.31.2-0.70.7
Bone: cortical thickness2.02.44.82.12.12.02.1-1.22.21.51.41.51.62.1-2.11.32.1-0.6-0.7-0.41.1-0.7-0.1-1.4-0.1
Bone: cortical tissue density1.11.54.6-0.50.20.30.12.20.11.00.61.0-0.6-0.10.10.3-0.12.12.01.80.81.82.11.51.5
Condit. Reinf. active minus inactive responses0.50.61.6-0.5-0.1-0.4-0.60.9-0.90.3-0.3-0.0-0.9-0.40.40.9-0.30.81.01.10.51.01.01.21.0
Condit. Reinf. active-inactive response ratio0.30.31.10.0-0.3-0.7-0.80.3-1.0-0.1-0.4-0.5-0.7-0.70.70.2-0.60.30.20.3-0.40.40.70.80.2
Condit. Reinf. active responses1.01.23.2-0.70.40.0-0.31.4-0.50.80.20.7-0.9-0.10.11.4-0.11.31.61.81.41.61.31.71.7
Condit. Reinf. inactive responses0.40.51.5-0.80.30.40.21.00.10.50.40.8-0.20.0-0.00.70.00.81.11.21.21.00.40.91.1
Incentive salience index mean0.91.13.0-0.10.4-0.1-0.51.2-0.70.8-0.00.5-1.1-0.40.41.7-0.41.11.41.60.91.41.41.61.6
Condit. Reinf. lever presses1.01.45.40.41.10.70.31.1-0.01.40.81.2-0.50.1-0.12.30.01.01.51.51.61.41.31.51.9
Condit. Reinf. active minus inactive responses0.20.30.70.60.00.20.3-0.60.3-0.20.1-0.00.70.4-0.4-0.60.3-0.6-0.8-0.8-0.3-0.7-0.7-0.6-0.7
Condit. Reinf. active-inactive response ratio0.10.10.8-0.8-0.6-0.5-0.40.1-0.5-0.4-0.2-0.3-0.1-0.10.1-0.9-0.10.3-0.1-0.0-0.20.1-0.10.3-0.3
Condit. Reinf. active responses0.40.51.61.30.70.70.8-0.81.00.20.10.30.60.9-0.80.40.8-0.9-0.6-0.80.1-0.8-0.6-1.1-0.3
Condit. Reinf. inactive responses0.81.04.62.11.51.11.2-0.81.40.80.40.80.41.0-1.01.61.0-0.7-0.3-0.40.5-0.60.3-1.10.2
Condit. Reinf. lever presses0.40.51.30.81.10.90.8-1.10.60.50.30.50.90.5-0.50.80.6-1.1-0.7-0.50.3-0.7-0.5-0.5-0.2
Condit. Reinf. lever reinforcers received0.60.82.01.20.60.70.8-1.21.0-0.10.10.10.90.9-0.90.10.8-1.3-1.0-1.2-0.1-1.2-1.0-1.4-0.8
Conditioned reinforcement - actives0.10.20.70.10.30.10.00.1-0.20.60.60.30.00.2-0.2-0.00.30.60.20.40.80.40.80.60.3
Conditioned reinforcement - inactives0.20.31.7-0.2-0.9-0.8-0.80.0-0.8-0.7-0.4-0.8-0.4-0.50.5-1.3-0.50.1-0.3-0.1-0.3-0.1-0.10.2-0.5
Conditioned locomotion0.20.20.7-0.6-0.0-0.4-0.50.1-0.70.10.1-0.2-0.3-0.70.7-0.3-0.50.50.10.40.10.40.80.70.1
Patch foraging indifference point 0 sec2.24.014.33.82.22.42.50.02.92.32.32.31.32.6-2.50.32.51.60.20.21.60.62.3-0.80.3
Patch foraging indifference point AUC2.63.89.60.83.13.02.7-1.02.02.62.52.52.32.1-2.12.62.1-0.50.00.42.4-0.10.1-0.10.9
Delay disc. indifference point, 0s delay0.40.41.3-0.0-0.0-0.8-0.8-0.6-0.4-0.6-1.2-0.8-1.0-0.70.70.9-0.6-1.0-0.30.0-0.9-0.5-0.6-0.30.1
Delay disc. indifference point, 16s delay0.60.71.90.8-0.2-0.6-0.4-1.2-0.2-0.8-0.7-0.9-0.1-0.10.1-0.5-0.1-1.4-1.2-1.0-0.7-1.3-0.6-1.3-1.1
Delay disc. indifference point, 2s delay0.91.03.21.40.00.00.4-1.60.7-0.5-0.4-0.60.60.4-0.4-0.80.3-1.3-1.6-1.5-0.6-1.6-0.5-1.8-1.6
Delay disc. indifference point, 24s delay0.30.31.21.1-0.0-0.10.2-0.50.4-0.3-0.1-0.2-0.10.8-0.8-0.50.8-0.2-0.6-0.4-0.2-0.60.5-1.0-0.7
Delay disc. indifference point, 4s delay0.80.82.20.6-0.6-0.7-0.4-1.2-0.2-1.0-0.7-1.0-0.1-0.60.6-1.0-0.5-1.0-1.4-1.4-0.7-1.2-0.5-1.2-1.5
Delay disc. indifference point, 8s delay0.81.01.90.2-0.7-1.2-0.9-1.2-0.8-1.2-1.2-1.4-0.5-0.70.7-0.8-0.6-1.3-1.2-0.9-1.3-1.2-0.6-0.9-1.2
Indifference point function ln k3.05.211.8-1.5-3.2-3.4-3.31.4-2.6-2.9-3.0-2.8-3.0-2.82.8-1.8-2.80.60.40.1-2.70.60.30.8-0.3
Indifference point function log k3.05.211.8-1.5-3.2-3.4-3.31.4-2.6-2.9-3.0-2.8-3.0-2.82.8-1.8-2.80.60.40.1-2.70.60.30.8-0.3
Patch foraging total patch changes 0 sec1.93.513.33.62.12.32.30.12.72.22.22.21.12.4-2.40.32.31.50.20.31.50.72.3-0.70.3
Patch foraging total patch changes 12 sec5.67.314.93.53.93.73.5-1.03.33.53.43.42.43.4-3.42.43.40.40.00.43.10.21.3-0.80.9
Patch foraging total patch changes 18 sec9.214.028.84.45.15.45.2-0.45.04.94.84.93.24.5-4.53.04.41.50.81.24.20.72.5-1.01.6
Patch foraging total patch changes 24 sec4.88.317.63.74.14.24.2-2.23.73.43.63.13.43.6-3.62.03.4-0.5-1.1-0.62.3-0.80.8-1.6-0.1
Patch foraging total patch changes 6 sec5.07.716.03.53.84.03.9-1.33.53.53.73.33.03.4-3.41.73.40.5-0.4-0.12.8-0.11.6-1.00.3
Patch foraging time to switch 0 sec0.10.11.3-0.1-0.8-0.3-0.10.40.1-0.4-0.2-0.1-0.00.1-0.1-1.20.20.30.0-0.20.0-0.10.0-0.3-0.4
Patch foraging water rate 0 sec0.81.74.20.72.01.71.4-0.11.02.11.81.60.81.0-1.02.01.00.80.51.01.50.91.30.81.1
Patch foraging water rate 12 sec0.10.21.11.00.80.40.4-1.00.30.60.60.00.40.1-0.10.50.2-0.3-0.7-0.30.1-0.20.1-0.2-0.3
Patch foraging water rate 18 sec0.71.13.2-0.6-0.7-1.3-1.4-0.5-1.8-0.8-0.9-1.2-0.8-1.71.70.5-1.6-0.5-0.5-0.2-1.3-0.0-0.20.8-0.2
Patch foraging water rate 24 sec0.20.31.3-1.2-0.5-0.5-0.60.4-0.7-0.4-0.3-0.4-0.5-0.80.80.3-0.70.40.30.5-0.40.50.50.70.2
Patch foraging water rate 6 sec0.40.61.71.31.10.90.9-0.90.80.91.10.50.70.9-0.90.70.90.1-0.6-0.40.3-0.20.7-0.3-0.3
Seeking ratio, delayed vs. immediate footshock0.50.72.3-0.7-0.2-0.6-0.7-0.9-1.2-0.6-0.5-0.90.2-1.11.10.2-0.6-1.3-0.8-0.8-0.6-0.8-1.50.1-0.5
Distance traveled before self-admin1.92.46.10.62.52.01.6-0.11.42.52.22.31.21.4-1.42.01.60.60.81.12.20.80.50.81.4
Distance traveled after self-admin1.82.24.60.81.51.61.31.11.32.01.92.00.61.1-1.10.91.21.81.41.52.21.41.91.01.3
Extensor digitorum longus weight0.00.20.70.80.70.40.3-0.50.00.50.60.40.5-0.10.10.6-0.0-0.3-0.2-0.00.3-0.1-0.20.20.0
Bone: elastic displacement2.02.34.90.71.82.01.90.72.01.91.92.20.91.7-1.70.61.71.70.91.01.71.02.20.10.9
Bone: elastic work2.43.16.31.32.42.52.5-0.12.42.22.22.41.42.2-2.21.12.21.00.50.51.80.41.8-0.50.7
Bone: endosteal estimation1.73.710.9-0.6-1.0-0.9-0.7-2.6-1.3-1.8-1.4-2.11.1-1.31.3-1.2-1.1-3.2-2.6-2.5-2.1-2.6-3.3-1.3-2.4
Bone: endosteal perimeter1.02.05.3-0.4-1.2-1.3-1.2-1.4-1.3-1.8-1.5-1.8-0.0-1.31.3-0.8-1.3-2.1-1.5-1.5-1.8-1.5-2.3-0.7-1.4
Epididymis fat weight0.61.94.8-0.4-1.3-1.6-1.5-1.2-1.4-1.7-1.5-1.8-0.4-1.31.3-1.2-1.3-1.6-1.5-1.4-1.6-1.2-2.2-0.4-1.3
Delta time in closed arm before/after self-admin4.44.110.6-0.6-1.6-1.8-1.6-2.1-1.5-2.5-2.3-2.7-0.2-1.41.4-1.1-1.5-3.1-2.3-2.3-2.4-2.4-3.3-1.5-2.1
Delta time in open arm before/after self-admin3.02.95.7-2.1-1.6-1.7-2.02.4-1.9-0.8-1.3-0.7-2.2-2.02.00.2-2.11.62.01.8-0.61.90.92.11.5
Diff in mean of infusions in LGA sessions0.10.20.4-0.00.10.50.6-0.20.60.20.30.30.60.6-0.6-0.40.5-0.2-0.2-0.20.5-0.4-0.1-0.5-0.3
Delay discount exponential model param0.91.03.0-1.20.10.40.01.7-0.20.80.60.9-0.2-0.20.20.9-0.21.41.71.40.71.70.61.71.6
Extinction: sum of active levers before priming1.71.96.3-0.9-0.8-1.5-1.61.1-1.5-0.5-1.1-0.9-2.3-1.71.70.5-1.71.50.91.3-0.61.42.51.40.8
Active lever presses in extinction session 61.81.83.6-1.9-1.8-1.8-1.80.9-1.8-1.5-1.8-1.4-1.7-1.71.7-0.5-1.50.30.50.6-1.30.50.50.80.2
Bone: final force2.03.26.02.42.32.32.4-2.12.21.61.91.52.32.0-2.11.02.0-1.2-1.4-1.30.9-1.4-0.5-1.7-0.7
Bone: final moment1.62.54.92.02.22.12.2-1.92.01.41.71.42.01.8-1.81.11.7-1.2-1.2-1.10.8-1.2-0.6-1.4-0.5
Food consumed during 24 hour testing period0.50.72.60.70.10.00.1-1.5-0.2-0.30.1-0.60.9-0.10.1-0.4-0.1-1.5-1.3-1.3-0.6-1.3-1.6-0.8-1.0
Glucose0.00.10.20.10.20.20.3-0.30.40.30.50.20.4-0.0-0.0-0.20.10.1-0.3-0.10.1-0.10.2-0.1-0.2
Heart weight1.32.05.61.32.11.81.8-1.90.92.02.41.32.11.1-1.11.21.3-0.7-1.1-0.81.4-0.90.3-0.5-0.5
Delay discount hyperbolic model param1.01.13.5-1.30.20.40.01.7-0.30.90.70.9-0.2-0.20.20.9-0.21.51.71.50.71.70.61.91.6
Intermittent access intake day 1-15 change0.10.30.90.90.00.50.6-0.00.60.30.70.40.90.4-0.4-0.90.50.5-0.2-0.30.6-0.0-0.1-0.1-0.5
Intermittent access intake escalation0.10.10.80.6-0.20.30.30.10.30.10.50.20.60.2-0.2-0.90.20.5-0.1-0.30.40.0-0.20.0-0.5
Intermittent access intake escalation 20.00.00.20.3-0.30.0-0.00.3-0.0-0.10.00.00.2-0.10.1-0.4-0.20.40.10.10.10.30.00.3-0.1
Intermitt. access day 1 inactive lever presses0.00.10.50.00.0-0.2-0.30.6-0.10.1-0.10.1-0.50.2-0.20.50.00.40.70.60.20.60.00.60.7
Intermitt. access day 15 inactive lever presses0.10.10.4-0.1-0.2-0.3-0.4-0.1-0.6-0.3-0.5-0.4-0.2-0.50.50.1-0.7-0.4-0.10.0-0.5-0.2-0.50.20.0
Intermitt. access escalation Index0.50.71.40.11.11.11.2-0.11.21.11.11.10.61.0-1.00.61.10.40.10.11.00.01.1-0.40.3
Intermittent access day 1 total infusions1.01.63.5-1.9-1.3-1.5-1.61.4-1.9-0.8-1.1-0.9-1.7-1.31.3-0.2-1.30.71.21.3-0.71.00.81.40.9
Intermittent access day 15 total infusions0.81.23.0-1.4-1.7-1.4-1.51.0-1.7-1.1-0.9-1.1-0.9-1.41.4-1.2-1.20.50.50.6-0.70.5-0.11.1-0.0
Intermittent access terminal intake (last 3 days)0.81.02.3-1.2-1.3-1.0-1.21.5-1.5-0.6-0.6-0.6-0.9-1.11.1-0.6-0.90.91.21.2-0.21.00.31.50.7
Intermittent access total infusions2.32.86.0-2.5-2.0-2.0-2.22.0-2.4-1.3-1.3-1.3-1.8-2.02.0-0.8-1.81.11.51.5-0.81.30.61.90.9
Intermittent access day 1 locomotion0.60.72.6-1.6-1.0-0.9-1.01.1-1.0-0.6-0.7-0.6-0.9-0.90.9-0.5-0.90.60.80.8-0.50.70.40.90.5
Intermittent access day 15 total locomotion0.30.51.9-0.4-1.1-0.9-0.8-0.0-0.9-0.8-0.5-0.9-0.2-0.90.9-1.4-0.8-0.1-0.4-0.4-0.6-0.2-0.30.1-0.7
Intermittent access total locomotion0.40.52.2-1.0-1.1-0.6-0.51.1-0.6-0.4-0.1-0.3-0.3-0.70.7-1.5-0.51.10.60.5-0.10.60.80.6-0.0
Intermittent access standard deviation0.40.82.8-1.0-0.5-0.9-1.21.1-1.2-0.2-0.4-0.2-1.1-0.90.90.5-0.90.71.11.10.01.2-0.21.71.1
Left kidney weight0.52.26.72.21.91.31.4-2.60.71.11.40.41.90.8-0.91.21.0-2.0-1.9-1.60.8-1.8-0.7-1.4-1.1
Right kidney weight0.31.55.41.71.20.70.8-2.30.30.40.6-0.11.40.4-0.40.70.5-2.0-1.8-1.7-0.0-1.7-1.0-1.3-1.2
Cocaine induced anxiety1.31.93.71.51.81.91.9-0.61.71.81.91.71.61.7-1.60.81.80.3-0.3-0.21.7-0.10.7-0.50.1
Post-drug Anxiety3.33.58.12.82.62.62.5-1.51.92.42.52.12.42.0-2.01.52.2-0.4-0.7-0.52.2-0.50.1-0.6-0.1
Baseline Anxiety0.60.71.91.41.21.11.0-0.40.61.11.01.00.80.6-0.71.40.6-0.40.10.11.1-0.0-0.40.00.5
Tail length0.20.71.80.30.10.50.7-1.10.5-0.3-0.0-0.21.00.5-0.6-0.20.5-1.3-1.1-1.2-0.5-1.3-1.0-1.3-1.0
Length with tail0.62.57.52.00.10.51.0-2.21.0-0.6-0.1-0.71.50.9-0.9-0.80.8-2.2-2.3-2.4-1.1-2.4-1.4-2.7-2.1
Length without tail1.03.29.32.1-0.5-0.10.5-2.40.8-1.2-0.5-1.51.30.5-0.5-1.70.6-2.4-2.7-2.8-1.5-2.8-1.7-3.0-2.8
Times rat made contact with spout0.30.32.90.40.80.1-0.1-0.3-0.20.60.00.2-0.6-0.30.31.7-0.5-0.10.40.70.10.40.40.60.8
Lifetime Intake2.83.48.4-2.9-2.0-1.9-2.22.4-2.5-1.2-1.3-1.1-2.1-2.02.0-0.3-1.91.42.02.0-0.71.70.72.31.4
Liver weight, left1.21.94.50.2-0.4-1.3-1.3-1.7-1.7-1.3-1.3-1.7-0.4-1.91.90.4-1.8-2.1-1.5-1.3-1.5-1.4-1.7-0.3-1.0
Liver weight, right1.01.74.0-0.7-1.6-1.6-1.4-0.3-1.2-1.8-1.6-1.8-0.6-1.61.6-1.5-1.5-1.0-0.8-1.0-2.0-0.9-1.2-0.5-1.1
Locomotor activity2.13.310.83.32.82.32.1-1.62.02.42.72.01.81.9-1.91.41.90.1-0.8-0.51.9-0.20.5-0.6-0.1
Locomotor testing distance1.93.58.71.72.52.01.60.51.22.92.82.40.61.2-1.12.21.12.01.21.62.51.72.51.41.6
Locomotor testing rearing1.73.58.20.52.41.71.20.90.82.92.52.40.30.7-0.62.70.62.11.72.02.42.12.32.02.2
Locomotion in novel chamber1.41.83.91.81.11.41.8-1.51.90.71.00.81.51.7-1.7-0.31.5-0.7-1.3-1.20.6-1.30.1-2.0-1.2
Locomotion in novel chamber post-restriction1.01.62.81.61.61.41.5-1.71.41.21.41.01.61.5-1.40.71.4-0.9-1.2-0.91.0-1.0-0.5-1.1-0.7
Fecal boli incidents, locomotor time 10.70.92.91.2-0.20.30.6-1.10.6-0.20.6-0.21.30.6-0.6-1.60.8-0.5-1.4-1.6-0.3-1.1-0.8-1.3-1.7
Change in fecal boli incidents, locomotor task0.60.62.2-1.5-0.9-1.0-1.00.3-1.1-0.7-0.8-0.7-0.9-0.90.9-0.6-0.90.2-0.00.2-0.40.20.60.5-0.0
Time >=10cm from walls, locomotor time 10.91.03.41.80.71.21.20.01.50.81.21.11.31.3-1.3-0.31.50.2-0.1-0.41.1-0.2-0.5-0.7-0.3
Bouts of movement, locomotor time 10.91.03.20.7-0.50.40.9-0.60.9-0.40.5-0.01.41.0-1.0-1.80.9-0.4-1.1-1.30.1-1.3-0.3-1.6-1.7
Total resting periods, locomotor time 11.21.43.40.6-0.30.71.3-0.81.2-0.30.70.21.81.3-1.3-1.81.2-0.4-1.2-1.50.2-1.4-0.2-1.8-1.9
Rest time, locomotor task time 10.60.72.2-0.6-0.00.71.0-0.31.00.00.70.31.51.0-1.0-1.41.2-0.1-0.7-0.90.1-0.8-0.3-1.0-1.1
Distance moved, locomotor task time 10.91.35.41.51.20.4-0.10.70.11.20.30.9-1.20.0-0.02.3-0.30.91.31.51.01.51.31.31.9
Vertical activity count, locomotor time 10.61.55.81.11.00.2-0.41.0-0.31.10.20.7-1.3-0.30.32.4-0.61.11.61.91.11.71.31.82.1
Time >=10cm from walls, locomotor time 20.71.15.1-0.2-0.20.40.22.30.70.40.30.9-0.20.8-0.7-0.40.81.91.91.41.21.40.80.81.0
Bouts of movement, locomotor time 20.20.41.60.9-0.40.10.4-0.10.6-0.40.1-0.10.40.6-0.5-1.30.50.1-0.4-0.4-0.6-0.60.7-1.2-1.1
Total resting periods, locomotor time 20.20.41.31.00.10.40.7-0.30.80.00.50.30.70.8-0.7-0.90.80.1-0.4-0.3-0.3-0.60.8-1.1-0.9
Rest time, locomotor task time 20.91.23.30.40.81.21.5-1.31.20.71.40.81.81.2-1.2-0.41.6-0.3-1.2-1.10.2-1.00.1-1.1-1.1
Distance moved, locomotor task time 20.20.31.21.10.70.60.50.20.70.60.30.60.10.7-0.70.60.10.30.40.30.70.40.10.00.5
Vertical activity count, locomotor time 20.60.81.71.20.80.50.21.00.31.00.50.9-0.40.5-0.51.30.21.11.21.21.21.20.81.01.3
Light reinforcement 11.02.57.01.92.62.32.1-1.51.72.32.41.81.91.4-1.41.81.3-0.2-0.7-0.21.7-0.30.5-0.40.2
Light reinforcement 20.10.20.9-0.90.10.1-0.20.6-0.40.20.10.10.1-0.40.50.3-0.50.20.50.60.40.5-0.20.90.5
Bone: marrow area1.73.711.0-0.6-1.0-1.0-0.7-2.6-1.3-1.8-1.4-2.21.1-1.21.2-1.3-1.1-3.2-2.6-2.5-2.2-2.7-3.3-1.4-2.4
Bone: maximum diameter0.50.92.61.41.30.90.8-1.60.60.50.50.20.90.6-0.61.60.6-1.4-1.1-0.90.1-1.0-0.8-0.8-0.4
Bone: maximum force1.62.85.42.32.32.22.2-2.11.91.61.91.42.31.8-1.81.11.7-1.3-1.3-1.20.8-1.2-0.7-1.4-0.6
Bone: maximum moment1.22.14.51.92.11.91.9-1.91.61.31.61.21.91.5-1.51.11.4-1.2-1.2-1.00.6-1.1-0.9-1.1-0.4
Mean time between licks in bursts0.10.20.60.20.0-0.4-0.4-0.6-0.4-0.3-0.5-0.4-0.3-0.50.50.5-0.4-0.8-0.3-0.2-0.3-0.4-0.4-0.2-0.0
Mean num. licks in bursts0.60.93.10.6-1.0-1.1-0.8-0.4-0.5-1.2-1.3-1.3-0.8-0.80.8-0.9-0.9-0.7-0.8-1.0-1.8-0.9-0.3-1.0-0.8
Cd content in liver1.41.65.60.8-0.40.50.8-0.81.4-0.60.6-0.11.51.5-1.5-2.41.5-0.5-1.5-1.7-0.1-1.3-1.2-1.7-1.9
Co content in liver0.10.20.40.60.60.30.1-0.00.20.70.50.6-0.0-0.10.10.6-0.00.20.40.40.70.3-0.30.30.6
Cu content in liver1.51.89.93.21.01.31.4-0.02.01.21.41.60.72.0-2.0-0.21.90.90.0-0.21.30.20.5-0.90.0
Fe content in liver0.20.32.6-0.20.90.50.3-0.6-0.30.70.20.30.3-0.20.21.6-0.2-0.80.10.20.1-0.2-0.30.40.6
K content in liver0.20.20.60.6-0.3-0.4-0.50.7-0.1-0.3-0.5-0.1-0.8-0.10.20.0-0.10.40.60.30.00.60.10.30.5
Mg content in liver0.40.43.51.90.30.30.40.00.80.30.50.5-0.00.9-0.9-0.10.90.5-0.0-0.10.30.20.5-0.4-0.1
Mn content in liver0.70.82.21.2-0.0-0.10.0-1.4-0.1-0.5-0.0-0.50.80.1-0.1-0.50.1-1.3-1.5-1.4-0.5-1.2-1.4-0.9-1.2
Na content in liver0.50.62.71.60.90.40.4-1.40.40.2-0.2-0.20.20.1-0.11.10.1-1.4-0.8-0.8-0.4-0.9-0.6-0.8-0.3
Rb content in liver0.40.41.1-0.9-1.0-0.7-0.61.0-0.4-0.5-0.5-0.2-0.8-0.40.5-1.0-0.40.90.70.6-0.10.70.40.50.3
Se content in liver0.70.81.91.0-1.2-1.1-0.9-0.5-0.3-1.3-1.0-1.4-0.6-0.40.4-1.0-0.4-0.6-0.9-1.1-1.3-0.8-0.6-1.1-1.1
Sr content in liver0.30.30.80.40.1-0.0-0.1-0.6-0.4-0.2-0.1-0.50.3-0.90.90.0-0.9-0.7-0.7-0.5-0.5-0.4-0.4-0.0-0.5
Zn content in liver0.90.95.62.40.50.50.7-1.01.10.20.70.30.81.2-1.1-0.61.2-0.4-1.1-1.20.4-0.7-0.4-1.1-1.1
Bone: minimum diameter1.01.85.60.70.10.30.5-2.20.4-0.60.0-0.81.60.2-0.2-0.60.2-2.4-2.1-2.0-0.9-2.2-2.3-1.7-1.7
Time in familiar zone, hab. session 12.32.24.32.11.91.81.9-1.01.91.82.01.61.42.0-2.01.02.00.1-0.5-0.41.8-0.30.4-0.8-0.0
Time in novel zone, hab. session 10.90.92.8-0.9-1.0-0.7-0.81.7-0.6-0.6-0.8-0.3-1.0-0.70.7-1.1-0.81.31.21.0-0.61.11.00.90.6
Total zone transitions, hab. session 10.20.31.90.10.80.40.30.10.20.3-0.10.5-0.40.4-0.41.40.10.00.40.70.60.40.70.30.8
Total locomotion distance, hab. session 10.10.21.7-0.40.60.20.2-0.50.2-0.1-0.60.0-0.30.1-0.11.3-0.1-0.9-0.10.2-0.1-0.3-0.2-0.20.4
Locomotion velocity, hab. session 10.30.42.8-0.50.5-0.1-0.1-0.8-0.3-0.4-0.9-0.4-0.5-0.30.31.7-0.6-1.3-0.4-0.0-0.5-0.5-0.4-0.30.3
Time in familiar zone, hab. session 21.41.54.10.41.01.41.30.81.21.71.91.70.71.1-1.20.71.11.41.00.92.00.91.20.41.0
Time in novel zone, hab. session 20.60.62.2-0.6-0.8-0.9-0.9-0.1-0.8-1.1-1.2-1.1-0.6-0.70.7-1.0-0.6-0.4-0.4-0.3-1.5-0.2-0.3-0.0-0.6
Total zone transitions, hab. session 20.50.71.6-1.2-0.6-0.8-1.00.7-1.3-0.6-0.9-0.6-0.9-1.01.0-0.1-1.30.40.50.7-0.60.70.31.20.4
Total locomotion distance, hab. session 20.10.20.5-0.3-0.1-0.4-0.5-0.0-0.5-0.6-0.7-0.4-0.5-0.50.50.0-0.6-0.1-0.00.2-0.70.20.10.40.0
Locomotion velocity, hab. session 20.20.20.7-0.1-0.1-0.4-0.5-0.4-0.6-0.6-0.8-0.6-0.4-0.50.50.2-0.7-0.5-0.3-0.1-0.8-0.1-0.10.2-0.1
Novel to familiar place preference ratio2.12.38.3-2.9-2.4-1.7-1.71.9-1.4-1.8-1.7-1.3-1.1-1.51.5-2.1-1.50.71.10.5-1.40.7-0.20.90.1
Novelty place preference1.82.07.1-2.7-2.2-1.5-1.51.7-1.3-1.7-1.6-1.3-0.9-1.41.4-2.1-1.50.50.80.4-1.40.4-0.50.7-0.0
Time in novel zone, NPP test1.61.77.0-2.7-2.0-1.3-1.31.9-1.1-1.4-1.4-1.0-0.9-1.31.3-1.9-1.30.81.10.7-1.10.7-0.20.90.2
Total zone transitions, NPP test0.81.22.90.40.90.30.01.40.40.6-0.30.9-1.30.4-0.41.70.31.31.51.71.01.61.71.01.7
Total locomotion distance, NPP test0.20.30.80.50.80.50.50.30.70.1-0.20.6-0.40.6-0.60.80.50.40.40.60.30.50.9-0.10.6
Locomotion velocity, NPP test0.10.20.50.60.40.30.3-0.30.7-0.4-0.60.1-0.30.5-0.50.40.4-0.3-0.3-0.1-0.3-0.20.3-0.7-0.1
Intraocular pressure0.81.14.80.0-0.1-0.10.0-1.8-0.5-0.5-0.3-0.61.1-0.80.8-0.5-0.9-1.8-1.5-1.4-0.8-1.5-2.2-0.6-1.2
Delta distance traveled before/after self-admin0.50.52.5-0.6-1.4-0.5-0.31.1-0.4-0.6-0.3-0.5-0.1-0.60.6-1.6-0.60.90.40.3-0.20.31.10.2-0.4
Delta ambulatory time before/after self-admin1.01.24.7-1.2-2.1-1.3-1.11.3-1.0-1.4-1.0-1.1-0.6-1.21.2-2.2-1.20.70.40.1-0.80.30.30.3-0.5
Parametrial fat weight0.71.74.0-1.3-1.5-1.7-1.70.5-1.7-1.3-1.5-1.5-1.6-2.02.0-0.3-1.90.00.20.4-1.40.20.40.70.1
Pavlov. Cond. lever latency0.20.32.1-0.4-0.5-0.10.10.70.30.00.50.30.10.1-0.1-1.40.11.30.20.2-0.40.51.00.0-0.4
Pavlov. Cond. magazine entry latency0.50.62.50.40.4-0.1-0.1-1.6-0.8-0.0-0.3-0.80.4-0.60.61.0-0.5-1.6-1.2-0.8-0.8-1.1-0.7-0.2-0.6
Pavlov. Cond. change in total contacts0.50.62.80.0-0.1-0.2-0.1-1.2-0.4-0.6-0.7-1.00.3-0.40.40.2-0.3-1.7-1.0-0.8-0.5-1.2-1.1-0.7-0.7
Pavlov. Cond. index score0.40.53.40.30.90.20.0-1.2-0.60.3-0.2-0.30.2-0.40.41.9-0.3-1.5-0.5-0.20.1-0.6-0.70.20.2
Pavlov. Cond. latency score0.40.52.60.50.70.1-0.0-1.2-0.40.0-0.3-0.50.2-0.30.31.5-0.2-1.6-0.7-0.4-0.1-0.8-1.0-0.2-0.0
Pavlov. Cond. lever contacts0.30.42.20.20.3-0.3-0.5-0.4-0.7-0.3-0.9-0.6-0.7-0.60.61.5-0.6-1.00.10.2-0.0-0.2-0.40.20.6
Pavlov. Cond. magazine entry number0.91.15.0-0.8-1.0-0.5-0.62.20.2-0.2-0.00.5-1.10.1-0.1-1.30.02.11.61.10.71.51.00.70.8
Pavlov. Cond. intertrial magazine entries3.03.612.2-1.2-0.6-0.5-0.83.5-0.10.3-0.31.1-2.2-0.10.10.2-0.13.43.12.81.33.03.02.02.4
Pavlov. Cond. lever-magazine prob. diff.0.30.43.30.20.80.1-0.1-0.9-0.70.3-0.3-0.30.0-0.50.51.8-0.4-1.2-0.30.00.1-0.4-0.50.30.4
Pavlov. Cond. response bias0.50.75.00.21.20.50.3-1.5-0.50.5-0.1-0.10.4-0.40.42.2-0.3-1.7-0.7-0.2-0.0-0.7-0.60.20.3
Pavlov. Cond. lever latency0.60.92.1-1.5-1.0-1.1-1.1-0.3-1.2-0.9-0.9-1.2-0.5-1.31.3-0.2-1.4-0.6-0.3-0.3-1.1-0.3-0.90.3-0.3
Pavlov. Cond. magazine entry latency0.60.71.9-0.7-1.4-1.3-1.20.8-1.1-1.2-1.1-1.0-1.1-0.90.9-0.6-0.80.20.40.1-0.40.10.20.2-0.0
Pavlov. Cond. change in total contacts0.40.71.60.80.20.60.7-1.00.6-0.10.40.01.30.8-0.8-0.80.9-0.9-1.1-1.10.4-1.1-0.7-1.1-1.1
Pavlov. Cond. index score0.20.20.91.00.20.40.5-0.00.60.00.30.30.40.8-0.7-0.30.8-0.1-0.1-0.30.5-0.30.1-0.6-0.3
Pavlov. Cond. latency score0.10.20.60.7-0.10.20.40.00.5-0.20.20.10.40.7-0.7-0.60.8-0.1-0.2-0.40.4-0.3-0.0-0.7-0.4
Pavlov. Cond. lever contacts0.50.72.01.41.01.11.00.21.10.90.81.10.41.1-1.10.51.20.50.20.30.90.30.9-0.20.4
Pavlov. Cond. magazine entry number0.10.10.2-0.30.30.30.3-0.40.30.20.20.10.50.0-0.0-0.2-0.1-0.1-0.3-0.2-0.4-0.1-0.1-0.1-0.3
Pavlov. Cond. intertrial magazine entries0.20.41.30.90.90.70.8-0.70.50.91.10.80.80.3-0.30.50.10.3-0.4-0.20.4-0.00.5-0.0-0.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.90.90.20.50.6-0.10.60.10.40.40.60.8-0.8-0.30.9-0.1-0.2-0.30.6-0.30.0-0.6-0.3
Pavlov. Cond. response bias0.20.21.41.20.50.50.40.10.50.30.20.5-0.00.7-0.70.40.70.10.10.10.50.10.5-0.30.3
Time in closed arm before self-admin2.93.77.51.21.92.21.91.51.42.72.52.70.81.4-1.31.51.42.31.92.02.51.92.71.31.9
Time in closed arm after self-admin0.20.20.8-0.5-0.4-0.2-0.1-0.2-0.1-0.5-0.5-0.50.2-0.40.4-0.3-0.5-0.9-0.2-0.3-0.4-0.6-0.9-0.5-0.2
Time in open arm before self-admin4.34.712.00.3-0.6-0.50.1-3.4-0.0-1.7-1.0-1.91.5-0.10.1-1.50.1-3.4-3.5-3.5-1.8-3.4-3.3-2.8-3.1
Time in open arm after self-admin1.11.22.5-1.3-1.1-1.4-1.51.1-1.5-0.8-1.0-0.8-1.6-1.41.40.0-1.40.90.70.7-0.71.00.61.30.5
Bone: periosteal estimation1.02.27.41.21.00.91.0-2.70.5-0.00.4-0.31.90.4-0.50.40.5-2.7-2.2-2.1-0.6-2.2-2.3-1.6-1.6
Bone: periosteal perimeter0.91.64.41.61.11.01.1-2.10.80.30.80.21.70.7-0.70.60.8-1.9-1.8-1.60.1-1.6-1.7-1.3-1.1
Bone: post-yield work0.81.22.9-0.4-0.9-1.2-1.3-0.3-1.6-1.2-1.2-1.3-0.6-1.61.5-0.3-1.6-0.9-0.6-0.5-1.7-0.4-1.10.5-0.4
Progressive ratio test 1 active lever presses1.11.43.1-1.8-1.6-1.5-1.60.8-1.7-1.3-1.3-1.3-1.1-1.41.4-0.9-1.40.00.40.6-1.20.3-0.10.80.1
Progressive ratio test 1 breakpoint0.91.02.7-1.6-1.4-1.3-1.30.6-1.6-1.1-1.1-1.2-0.9-1.31.3-0.8-1.2-0.00.30.5-1.00.2-0.10.7-0.0
Progressive ratio test 1 inactive lever presses0.20.31.0-0.9-0.4-0.4-0.51.0-0.5-0.1-0.1-0.1-0.5-0.30.30.0-0.30.60.90.80.20.70.10.80.8
Progressive ratio test 2 active lever presses0.40.51.3-1.1-0.8-0.7-0.80.9-1.1-0.3-0.2-0.5-0.5-0.70.7-0.6-0.60.80.71.00.10.70.61.10.3
Progressive ratio test 2 breakpoint0.40.51.1-1.1-0.8-0.6-0.70.9-1.0-0.3-0.2-0.4-0.4-0.70.7-0.6-0.50.80.60.90.10.70.51.00.3
Progressive ratio test 2 inactive lever presses0.10.10.50.6-0.4-0.2-0.30.4-0.40.00.3-0.1-0.10.1-0.1-0.70.20.50.20.30.40.30.20.4-0.0
Incentive Sensitization - Responses0.30.41.2-0.6-0.8-0.5-0.51.1-0.7-0.3-0.2-0.3-0.7-0.30.3-0.6-0.31.00.81.00.10.81.00.80.4
Incentive Sensitization - Breakpoint0.30.41.2-0.4-0.8-0.4-0.41.1-0.5-0.2-0.1-0.2-0.6-0.20.2-0.6-0.21.10.81.00.20.81.10.70.4
Sum of active levers in priming session hrs 5-60.30.30.8-0.1-0.6-0.4-0.1-0.4-0.1-0.7-0.5-0.7-0.1-0.10.1-0.6-0.10.0-0.7-0.6-0.7-0.50.8-0.7-0.9
Progressive ratio0.40.71.51.20.81.01.0-0.81.10.40.50.61.01.1-1.20.51.0-0.6-0.5-0.60.6-0.7-0.5-0.8-0.3
Food seeking constrained by brief footshock0.40.51.91.40.60.70.70.20.80.70.81.00.40.9-0.90.20.90.80.2-0.00.80.41.00.00.2
Seeking ratio, punishment vs. effort0.40.61.2-0.7-0.6-0.7-0.81.1-0.8-0.2-0.3-0.3-1.1-0.80.9-0.3-0.81.00.90.9-0.31.01.00.90.7
Retroperitoneal fat weight0.10.51.6-0.5-0.3-0.2-0.1-0.9-0.3-0.4-0.1-0.60.8-0.60.6-0.7-0.5-1.0-1.1-0.8-0.6-0.9-1.3-0.3-1.0
Reaction time number correct0.81.53.6-0.9-0.1-0.4-0.81.7-0.90.3-0.30.2-1.4-1.11.11.2-1.21.51.81.90.51.81.51.91.8
Reaction time mean minus median0.10.21.10.30.20.50.5-0.40.10.20.60.41.00.1-0.0-0.20.2-0.1-0.4-0.60.5-0.3-0.2-0.1-0.6
Reaction time mean minus median AUC0.61.45.30.90.71.41.5-1.31.10.61.40.92.31.2-1.2-0.61.2-0.8-1.2-1.31.0-1.2-1.0-1.0-1.3
Reaction time num false alarms0.60.82.1-0.40.2-0.5-0.70.7-1.00.50.0-0.0-1.1-1.01.01.1-1.00.81.01.30.31.11.31.41.2
Reaction time num false alarms AUC0.71.12.5-0.9-0.0-0.8-1.10.9-1.30.2-0.3-0.3-1.4-1.21.21.1-1.20.81.11.40.11.21.21.61.2
Reaction time trials correct on left0.81.53.6-0.9-0.1-0.4-0.81.7-0.90.3-0.30.2-1.4-1.11.11.2-1.21.51.81.90.51.81.51.91.8
Reaction time trials on left0.81.63.6-0.9-0.2-0.5-0.81.7-0.90.2-0.40.2-1.5-1.11.11.2-1.31.41.81.90.41.81.41.91.8
Reaction time mean0.50.82.4-0.8-1.4-1.0-0.90.0-1.0-1.3-0.8-1.1-0.0-1.01.0-1.6-0.9-0.4-0.4-0.8-1.0-0.5-1.0-0.0-1.0
Reaction time mean AUC1.01.63.6-1.2-1.8-1.5-1.3-0.1-1.4-1.8-1.3-1.5-0.2-1.41.4-1.9-1.4-0.6-0.7-0.9-1.4-0.7-1.2-0.1-1.3
Median of all reaction times1.52.14.3-1.5-2.1-1.9-1.80.1-1.7-2.0-1.7-1.9-0.7-1.61.7-1.9-1.6-0.6-0.5-0.8-1.7-0.5-1.30.1-1.1
Reaction time omissions1.01.42.5-0.9-1.5-1.6-1.4-0.5-1.3-1.6-1.2-1.5-0.6-1.41.5-1.1-1.4-0.7-1.0-1.0-1.2-0.7-1.0-0.2-1.2
Reaction time false alarm rate0.20.30.8-0.6-0.4-0.8-0.90.1-0.9-0.3-0.4-0.6-0.7-0.80.80.1-0.70.00.10.3-0.50.20.20.50.1
Reaction time premature initiation rate1.11.55.80.50.40.60.51.80.80.90.71.2-0.70.6-0.70.60.52.21.71.61.41.72.40.71.3
Reaction time premature initiations1.32.38.50.30.50.60.42.30.61.10.71.4-1.00.4-0.41.10.32.62.22.11.62.22.91.31.9
Std. dev. reaction times0.10.10.70.2-0.00.30.4-0.00.20.10.50.40.80.1-0.1-0.50.20.1-0.1-0.50.5-0.2-0.1-0.1-0.5
Reaction time trials completed0.81.63.6-0.9-0.2-0.5-0.81.7-0.90.2-0.40.2-1.5-1.11.11.2-1.31.41.81.90.41.81.41.91.8
Reaction time trials AUC0.81.43.4-0.70.0-0.3-0.71.5-0.80.3-0.30.3-1.4-1.01.01.4-1.21.31.71.80.51.81.41.91.8
Run reversals in cocaine runway, females1.31.32.91.31.31.21.20.21.61.31.51.70.61.6-1.50.51.71.10.40.01.50.60.8-0.20.5
Run reversals in cocaine runway, males0.40.41.1-0.7-0.4-0.3-0.4-0.4-1.0-0.4-0.2-0.60.4-1.01.0-0.2-0.7-0.9-0.4-0.5-0.5-0.5-1.00.3-0.4
Latency to leave start box in cocaine runway0.30.41.30.0-0.0-0.5-0.6-0.7-0.7-0.3-0.9-0.8-0.6-0.60.71.2-0.6-1.1-0.30.1-0.7-0.5-0.5-0.20.1
Latency to leave start box in cocaine runway, F0.40.52.50.60.3-0.0-0.0-1.3-0.4-0.1-0.4-0.60.3-0.50.60.9-0.5-1.6-1.0-0.5-0.4-1.1-0.7-0.7-0.5
Latency to leave start box in cocaine runway, M0.80.73.0-0.7-0.7-1.1-1.20.9-0.8-0.6-1.2-0.8-1.7-0.70.70.6-0.60.30.90.8-0.70.70.30.70.9
Std. dev. time between licks in bursts3.24.38.52.32.82.92.8-1.02.82.32.52.52.32.9-2.91.12.9-0.1-0.2-0.12.5-0.30.0-0.90.3
Total sessions with >9 infusions0.60.82.8-1.7-1.1-0.9-1.01.2-1.1-0.6-0.7-0.6-0.9-0.90.9-0.2-0.80.51.01.0-0.50.7-0.11.00.7
Short access day 1 total inactive lever presses1.31.74.6-2.0-0.5-0.9-1.31.7-1.40.0-0.4-0.1-1.5-1.01.00.8-1.01.21.82.00.21.70.72.11.7
Short access day 10 total inactive lever presses0.00.10.60.50.3-0.1-0.3-0.20.10.10.00.1-0.20.2-0.20.30.1-0.1-0.1-0.20.10.1-0.80.20.2
Short access day 1 total infusions1.92.57.0-2.6-1.7-1.9-2.11.5-2.1-1.4-1.7-1.4-2.0-1.91.9-0.1-1.70.41.21.1-1.20.9-0.11.50.9
Short access day 10 total infusions4.15.213.1-3.6-2.9-2.9-3.12.1-3.2-2.3-2.5-2.3-2.5-2.92.9-0.7-2.80.41.51.4-1.91.1-0.32.10.9
Short access total infusions2.93.710.3-3.2-2.1-2.1-2.42.2-2.5-1.4-1.7-1.4-2.3-2.22.20.0-2.10.91.91.8-1.11.50.22.11.5
Short access day 1 locomotion0.10.20.5-0.5-0.10.30.30.70.50.30.30.40.20.4-0.4-0.30.60.60.60.30.20.30.00.00.3
Short access day 10 total locomotion0.51.03.7-1.9-1.3-1.2-1.20.6-1.3-1.0-0.8-1.0-0.7-1.41.4-1.1-1.30.30.30.4-0.70.30.00.8-0.1
Short access total locomotion0.70.83.9-2.0-1.3-1.1-1.10.9-1.0-1.0-0.7-0.8-0.7-1.11.1-1.2-1.00.50.50.3-0.70.4-0.20.6-0.0
One hour access (0.3 mA shock)1.31.53.9-1.1-0.9-1.0-1.31.9-1.5-0.1-0.3-0.1-1.4-1.01.0-0.1-1.01.61.71.70.11.71.22.01.4
Compulsive drug intake0.50.61.71.10.80.80.9-1.30.70.60.80.31.00.7-0.70.00.7-0.6-1.0-0.90.4-0.8-0.2-0.8-0.8
One hour access (shock baseline)0.91.43.2-1.4-0.9-1.0-1.31.7-1.5-0.3-0.6-0.3-1.3-1.11.10.2-1.11.11.51.5-0.11.40.51.81.3
Social response proportion0.70.83.71.0-0.6-0.10.4-0.60.6-0.60.1-0.30.70.5-0.5-1.90.5-0.1-1.1-1.5-0.6-1.00.0-1.4-1.6
Social responses1.11.45.52.41.31.41.6-0.31.61.31.71.41.11.3-1.40.11.20.8-0.3-0.41.20.01.2-0.6-0.3
Social time0.81.22.6-0.5-1.6-1.6-1.40.0-1.2-1.5-1.0-1.5-1.0-1.21.2-1.6-1.20.1-0.5-0.6-1.3-0.30.4-0.1-1.0
Soleus weight0.30.85.2-0.31.30.4-0.0-1.1-0.90.60.00.10.4-1.11.12.3-1.0-1.4-0.30.20.2-0.2-0.91.00.6
Bone: stiffness1.52.48.52.00.60.10.3-2.80.1-0.5-0.2-0.81.10.1-0.10.40.0-2.9-2.3-2.3-1.1-2.3-2.6-1.8-1.6
Tibialis anterior weight0.10.31.20.90.90.50.3-0.70.10.50.40.30.50.0-0.01.1-0.0-0.7-0.4-0.30.4-0.3-0.5-0.00.0
Time to tail flick, vehicle, before self-admin0.60.72.2-1.5-0.6-0.9-1.00.8-1.1-0.4-0.7-0.4-0.9-1.11.10.3-0.90.30.80.6-0.10.7-0.31.20.7
Time to tail flick, vehicle, after self-admin1.11.44.5-0.5-1.0-0.50.0-1.30.0-1.2-0.5-1.20.90.2-0.2-2.10.1-1.1-1.7-1.8-1.4-1.7-1.3-1.5-2.0
Time to tail flick, test, before self-admin2.02.15.4-0.20.60.50.12.10.21.30.71.3-0.90.1-0.11.70.12.12.32.31.32.12.01.72.2
Time to tail flick, test, after self-admin0.60.61.5-0.4-0.3-1.0-1.0-0.6-1.0-0.7-1.2-0.9-1.0-0.80.90.9-0.9-1.0-0.5-0.3-1.2-0.4-0.4-0.10.0
Delta time to tail flick, vehicle, before/after SA1.81.75.00.1-1.4-1.1-0.6-1.1-0.2-1.8-1.3-1.7-0.1-0.10.1-2.2-0.3-1.1-1.6-1.6-2.1-1.5-0.7-1.7-2.0
Delta time to tail flick, test, before/after SA2.02.15.90.3-0.5-1.0-0.8-2.2-0.8-1.4-1.3-1.60.0-0.60.5-0.6-0.6-2.4-2.1-2.0-1.7-1.9-2.1-1.4-1.6
Tibia length1.54.011.51.00.30.41.0-3.40.6-0.8-0.1-1.22.20.7-0.7-0.60.6-3.4-3.2-3.3-1.1-3.4-2.3-2.9-2.7
Ambulatory time before self-admin2.03.07.00.62.62.11.70.11.52.62.32.51.01.7-1.62.31.80.91.01.42.31.11.10.91.6
Ambulatory time after self-admin1.51.75.5-0.00.50.90.71.70.61.41.51.50.10.7-0.7-0.00.82.31.61.71.71.72.31.31.1
Bone: tissue strength0.60.61.6-0.8-1.0-0.9-0.8-0.2-0.6-1.3-1.0-1.0-0.3-0.70.7-1.0-0.6-0.5-0.6-0.6-1.2-0.5-0.7-0.4-0.8
Total heroin consumption0.30.41.90.5-0.1-0.8-0.80.1-0.7-0.4-0.9-0.5-1.4-0.70.70.5-0.90.10.20.4-0.60.30.80.30.4
Bone: trabecular number1.22.04.72.21.81.81.8-1.81.51.31.81.21.91.5-1.50.71.5-0.9-1.2-1.21.2-1.1-0.4-1.1-0.6
Bone: trabecular spacing0.81.02.7-1.4-0.8-1.2-1.40.6-1.4-0.6-1.0-0.9-1.2-1.51.5-0.0-1.60.20.40.7-1.00.60.21.10.4
Bone: trabecular thickness2.12.65.22.32.22.02.0-1.61.91.51.71.61.72.1-2.11.32.2-1.0-0.9-0.81.6-1.0-0.5-1.4-0.2
Bone: trabecular tissue density0.30.51.40.20.40.20.11.00.40.60.20.7-0.70.2-0.21.00.41.01.20.91.10.90.80.41.2
Water consumed over 24 hours0.40.53.20.10.80.1-0.3-0.2-0.90.90.40.1-0.3-0.80.81.8-0.8-0.10.50.80.40.50.31.20.9
Number of responses in last shaping day0.50.51.1-0.6-0.8-1.0-1.00.0-0.7-1.0-1.0-0.9-0.7-0.80.8-0.4-0.8-0.6-0.2-0.1-1.1-0.2-1.0-0.0-0.2