Hub : Genes

Fbxo42

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Fbxo42 0.15 0.07 2.8e-06 0.05 0.09 0.1 0.08 7.3e-04 2.1e-05 8.6e-06 7.0e-05
2 Liver intron excision ratio chr5_153451427_153452403 0.06 0.04 8.3e-04 0.01 0.01 0.01 0.01 1.6e-02 2.5e-02 1.5e-02 2.7e-02
3 NAcc gene expression Fbxo42 0.32 0.09 0.0e+00 0.22 0.26 0.28 0.28 3.2e-25 3.9e-30 1.1e-32 8.9e-33
4 Liver mRNA stability Fbxo42 0.28 0.1 0.0e+00 0.21 0.21 0.2 0.2 1.7e-22 4.5e-23 3.5e-22 3.3e-22
5 Liver gene expression Fbxo42 0.04 0.03 2.3e-03 0.02 0.02 0 0.01 1.9e-03 3.6e-03 1.1e-01 8.1e-03
6 Brain mRNA stability Fbxo42 0.13 0.06 1.7e-13 0.15 0.14 0.15 0.16 1.1e-13 3.6e-13 5.2e-14 1.1e-14
7 PL gene expression Fbxo42 0.5 0.1 0.0e+00 0.27 0.34 0.34 0.34 4.9e-30 5.3e-38 2.3e-38 2.9e-38
8 NAcc mRNA stability Fbxo42 0.17 0.07 2.8e-15 0.12 0.14 0.14 0.14 1.9e-13 1.5e-15 5.6e-16 5.5e-16
9 BLA gene expression Fbxo42 0.56 0.11 0.0e+00 0.28 0.4 0.39 0.41 2.5e-15 1.2e-22 3.5e-22 1.6e-23
10 NAcc intron excision ratio chr5_153451427_153471882 0.09 0.04 6.9e-08 0.06 0.07 0.06 0.06 4.3e-07 3.0e-08 9.9e-08 1.9e-07
11 pVTA mRNA stability Fbxo42 0.12 0.06 8.4e-04 0.05 0.07 0.08 0.06 2.7e-03 8.0e-04 2.4e-04 9.2e-04
12 IL mRNA stability Fbxo42 0.31 0.16 2.2e-03 0.02 0.01 0 0.02 1.0e-01 1.6e-01 2.5e-01 8.9e-02
13 PL mRNA stability Fbxo42 0.16 0.06 1.1e-16 0.14 0.15 0.16 0.17 1.2e-15 1.2e-16 2.0e-17 7.5e-18
14 pVTA intron excision ratio chr5_153451427_153471882 0.18 0.09 2.2e-05 0.13 0.11 0.1 0.1 4.4e-06 2.0e-05 6.0e-05 2.9e-05
15 Adipose mRNA stability Fbxo42 0.18 0.09 0.0e+00 0.07 0.14 0.14 0.14 1.5e-08 5.1e-15 2.2e-15 5.0e-15
16 RMTg gene expression Fbxo42 0.21 0.11 4.3e-03 0.09 0.08 0.07 0.07 2.9e-03 3.1e-03 5.1e-03 7.4e-03
17 pVTA gene expression Fbxo42 0.3 0.11 5.7e-07 0.13 0.16 0.13 0.14 3.1e-06 2.4e-07 2.3e-06 1.0e-06
18 Adipose gene expression Fbxo42 0.32 0.11 0.0e+00 0.24 0.28 0.28 0.28 4.2e-26 1.1e-31 2.5e-31 1.3e-30
19 Brain gene expression Fbxo42 0.34 0.09 0.0e+00 0.38 0.36 0.37 0.37 1.2e-36 4.6e-35 5.0e-36 3.1e-36
20 IL gene expression Fbxo42 0.34 0.12 3.5e-06 0.09 0.02 0.12 0.14 3.2e-03 8.9e-02 6.6e-04 3.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.32.14.4-1.8-2.11.91.9-1.51.21.51.4-1.61.8-1.50.80.8-1.91.31.2-1.6-1.10.7-0.1
Area under the delay curve0.90.93.20.3-0.2-0.1-0.1-0.0-0.81.8-0.7-1.8-0.41.1-1.1-0.90.20.7-0.1-1.5-1.51.60.3
BMI with tail0.30.91.80.40.9-1.3-0.81.0-1.21.3-0.5-1.20.2-0.0-1.0-1.4-0.21.1-0.9-1.0-1.11.3-0.7
BMI without tail1.32.77.02.62.4-1.1-2.22.5-1.90.4-2.0-0.4-1.21.4-1.8-2.11.70.8-2.0-0.2-1.00.6-0.4
Body weight0.72.88.30.4-1.2-0.00.5-0.4-1.02.7-0.4-2.81.5-0.9-1.4-1.2-0.82.90.6-2.7-2.62.4-1.4
Weight adjusted by age0.91.03.30.10.8-0.9-0.00.5-0.71.70.0-1.51.0-0.7-0.5-0.9-0.60.1-0.6-1.3-1.01.7-1.8
Bone surface1.73.05.7-1.7-2.42.02.3-1.91.31.81.7-1.92.4-2.20.51.0-1.81.51.7-1.9-1.30.9-0.6
Bone volume1.42.45.1-1.7-2.22.32.0-1.51.11.81.2-1.91.8-1.50.40.6-1.61.71.4-1.9-1.50.7-0.3
Breakpoint value in progressive ratio session0.10.10.80.30.9-0.5-0.50.4-0.30.0-0.10.1-0.20.3-0.1-0.30.3-0.6-0.50.10.10.0-0.0
Number of licking bursts1.51.74.2-2.0-0.61.90.8-0.32.1-1.61.31.30.3-1.12.01.4-1.2-0.50.51.41.4-1.20.6
Context. condit. distance diff. score1.21.43.5-1.9-0.91.90.8-0.71.6-1.60.61.20.1-0.71.71.7-0.60.20.51.31.2-1.21.0
Locomotion velocity, session 12.02.26.9-0.70.51.8-0.60.81.1-2.5-0.32.3-1.51.01.40.80.8-0.7-0.82.31.7-2.61.7
Locomotion distance, session 11.21.54.5-0.10.31.1-0.60.60.5-1.8-0.61.7-1.81.70.50.60.9-1.0-0.81.81.4-1.82.1
Locomotion velocity, session 21.82.14.70.70.9-0.0-1.20.9-0.0-2.1-1.12.1-2.21.90.10.21.7-1.2-1.12.11.5-2.11.6
Locomotion distance, session 21.31.86.11.81.1-0.8-1.91.6-1.4-0.2-1.90.1-2.12.5-1.3-1.51.50.3-1.60.4-0.3-0.20.8
Locomotion velocity, session 30.40.41.5-0.5-0.60.3-0.1-0.00.5-1.10.11.0-0.40.00.60.70.3-0.4-0.21.11.0-1.20.8
Locomotion distance, session 30.50.52.0-0.5-0.41.10.2-0.10.8-1.30.10.9-0.1-0.30.80.90.50.1-0.11.00.8-1.40.3
Stereotopy head waving bouts, day 31.01.13.71.61.4-1.6-1.31.1-1.20.4-1.1-0.2-1.31.9-0.8-1.20.5-0.7-1.00.0-0.10.50.7
Stereotopy head waving duration, day 30.60.82.30.81.0-1.4-1.00.8-0.7-0.3-0.40.5-1.31.5-0.2-0.50.1-1.4-0.60.70.70.21.2
Locomotion velocity, session 71.41.53.8-1.4-0.81.11.4-1.31.2-1.21.10.91.5-1.91.31.8-1.50.11.30.71.0-1.0-0.8
Locomotion distance, session 70.60.72.6-1.2-0.41.61.0-0.60.8-0.80.60.51.0-1.30.71.1-0.60.20.50.40.5-0.8-0.6
Stereotopy head waving bouts, day 70.40.51.2-0.9-0.70.50.7-0.50.8-0.11.00.10.4-0.41.00.9-0.8-0.70.70.30.70.01.1
Stereotopy head waving duration, day 70.60.72.3-1.1-0.61.20.6-0.31.3-0.51.00.50.2-0.21.31.1-0.8-0.50.70.60.8-0.61.5
Locomotion velocity, session 80.81.02.80.91.00.2-1.41.1-0.6-1.3-1.70.9-1.61.4-0.4-0.50.70.6-0.71.10.3-0.90.6
Locomotion distance, session 80.40.63.5-1.3-1.11.90.5-0.50.9-0.7-0.10.3-0.10.00.90.9-0.51.00.40.50.2-0.61.0
Degree of sensitization distance0.30.31.00.21.0-0.6-0.00.3-0.70.5-0.1-0.40.4-0.2-0.8-0.5-0.2-0.2-0.3-0.5-0.30.8-1.0
Degree of sensitization stereotypy0.91.02.0-1.4-1.40.91.3-1.11.00.41.4-0.61.2-1.30.91.0-0.90.11.2-0.30.10.40.5
Conditioned locomotion0.50.61.91.2-0.3-1.4-0.1-0.7-0.4-0.6-0.40.6-1.01.3-0.00.00.4-1.30.70.70.8-0.20.7
Cocaine response after cond. corrected4.14.611.33.33.4-3.4-2.62.6-2.90.8-1.8-0.7-0.91.2-2.8-2.61.8-0.2-2.1-0.5-1.01.5-1.8
Cocaine response after cond. not corrected2.02.29.12.32.6-3.0-1.71.7-2.00.5-0.8-0.4-0.30.4-1.8-1.70.8-0.7-1.1-0.3-0.41.3-1.6
Cocaine response before conditioning2.93.58.2-2.9-1.92.11.8-1.62.6-1.42.21.30.7-1.32.82.5-1.8-1.01.81.21.7-1.61.5
Saline control response1.62.16.4-1.4-2.20.42.0-2.01.21.21.8-0.71.6-1.41.41.2-2.5-0.32.1-1.0-0.20.50.1
Bone: connectivity density1.62.45.3-1.8-2.11.52.1-1.41.31.52.1-1.62.3-2.30.81.1-2.10.71.1-1.4-0.70.9-0.3
Bone: cortical apparent density1.01.34.4-0.60.1-0.20.2-0.20.9-1.60.91.8-0.30.01.71.1-0.6-2.1-0.21.61.9-1.50.8
Bone: cortical area1.72.66.1-2.3-2.52.02.3-2.21.81.01.8-1.11.7-1.41.11.5-1.90.72.1-1.0-0.40.00.5
Bone: cortical porosity0.50.62.60.90.5-0.8-0.2-0.1-0.60.2-0.7-0.1-1.11.6-1.2-0.50.6-1.60.20.10.30.20.8
Bone: cortical porosity1.92.15.81.91.6-1.5-1.51.1-1.80.4-1.8-0.4-1.82.4-2.2-1.71.7-0.9-0.9-0.1-0.40.50.4
Bone: cortical thickness2.23.77.6-2.8-2.71.82.6-2.72.6-0.12.50.11.4-1.12.22.4-2.2-0.92.30.21.1-0.61.5
Bone: cortical thickness1.61.84.6-1.2-2.21.72.1-2.11.40.71.3-0.81.5-1.10.91.3-1.70.62.1-0.8-0.30.3-0.2
Bone: cortical tissue density0.91.24.5-0.40.3-0.40.0-0.00.7-1.70.71.8-0.40.01.61.0-0.5-2.1-0.41.71.9-1.50.7
Condit. Reinf. active minus inactive responses0.50.61.20.60.90.5-0.60.90.2-0.9-0.30.9-1.01.0-0.0-0.10.4-0.9-0.40.90.7-1.01.1
Condit. Reinf. active-inactive response ratio0.30.31.10.60.70.0-0.81.1-0.10.0-0.20.2-0.81.0-0.3-0.50.4-0.7-0.50.20.1-0.30.9
Condit. Reinf. active responses0.81.02.90.30.60.9-0.30.60.8-1.70.11.5-0.90.60.70.70.1-1.10.01.61.4-1.71.3
Condit. Reinf. inactive responses0.40.41.90.00.20.40.1-0.10.6-1.40.21.1-0.1-0.20.50.80.2-0.40.11.11.0-1.10.2
Incentive salience index mean0.81.02.90.30.51.1-0.40.80.7-1.4-0.01.3-1.21.10.40.50.1-1.1-0.21.41.2-1.51.7
Condit. Reinf. lever presses0.91.23.2-0.3-0.31.60.20.31.3-1.60.51.5-0.70.41.11.2-0.5-0.90.21.51.4-1.81.7
Condit. Reinf. active minus inactive responses0.20.20.6-0.2-0.6-0.10.3-0.30.00.70.3-0.70.7-0.80.30.0-0.30.70.4-0.6-0.50.5-0.6
Condit. Reinf. active-inactive response ratio0.20.21.10.70.4-1.0-0.50.5-0.60.1-0.2-0.1-0.1-0.0-0.3-0.30.0-0.2-0.00.10.00.2-0.4
Condit. Reinf. active responses0.40.62.2-0.9-1.51.10.9-1.00.60.50.4-0.50.6-0.80.80.5-0.61.01.0-0.6-0.5-0.0-0.0
Condit. Reinf. inactive responses0.91.24.2-1.8-1.92.01.3-1.31.30.30.8-0.20.4-0.61.31.0-0.80.51.1-0.4-0.2-0.31.0
Condit. Reinf. lever presses0.40.62.8-0.9-1.11.70.9-0.60.70.40.3-0.60.7-0.80.50.6-0.61.00.7-0.6-0.6-0.2-0.3
Condit. Reinf. lever reinforcers received0.50.72.1-0.8-1.51.00.9-0.90.30.90.4-1.00.9-1.10.60.3-0.61.40.9-1.0-0.90.4-0.5
Conditioned reinforcement - actives0.30.31.0-0.50.20.40.20.20.9-0.00.90.10.2-0.21.00.6-0.8-0.60.40.20.5-0.21.0
Conditioned reinforcement - inactives0.30.31.0-0.5-0.50.30.2-0.10.8-0.60.90.50.2-0.41.00.7-0.8-0.30.40.60.7-0.60.6
Conditioned locomotion0.10.10.7-0.40.80.3-0.40.70.10.1-0.00.0-0.30.30.1-0.3-0.0-0.7-0.40.10.1-0.00.5
Patch foraging indifference point 0 sec2.13.49.8-2.0-3.10.42.5-2.81.8-0.12.40.31.3-1.31.82.4-2.0-2.02.60.41.5-0.11.3
Patch foraging indifference point AUC5.15.814.6-3.8-2.43.73.1-2.33.4-0.62.90.32.5-3.02.82.8-2.80.62.6-0.00.6-1.2-0.1
Delay disc. indifference point, 0s delay0.91.03.70.80.40.9-0.90.6-0.60.3-1.5-0.5-1.51.9-1.3-0.91.31.0-0.7-0.3-0.80.11.1
Delay disc. indifference point, 16s delay0.80.92.70.10.1-0.0-0.20.3-0.81.6-0.7-1.6-0.31.0-0.8-0.90.20.9-0.1-1.5-1.61.50.3
Delay disc. indifference point, 2s delay0.91.03.60.4-0.8-0.30.5-0.7-0.61.9-0.3-1.80.40.1-0.9-0.5-0.30.60.6-1.6-1.41.7-0.7
Delay disc. indifference point, 24s delay0.30.31.00.3-0.5-0.40.4-0.5-0.11.00.2-0.80.00.5-0.0-0.1-0.3-0.41.0-0.7-0.40.90.3
Delay disc. indifference point, 4s delay1.11.12.81.20.5-1.0-0.60.4-1.31.7-0.9-1.6-0.41.1-1.3-1.20.20.5-0.6-1.3-1.31.7-0.2
Delay disc. indifference point, 8s delay1.01.02.60.40.4-0.1-0.70.7-0.91.6-0.9-1.5-0.61.2-1.4-1.30.70.7-0.7-1.3-1.51.40.1
Indifference point function ln k4.36.110.93.22.7-3.0-3.32.7-3.30.1-3.00.0-3.03.2-2.9-2.83.1-0.8-3.00.4-0.40.70.7
Indifference point function log k4.36.110.93.22.7-3.0-3.32.7-3.30.1-3.00.0-3.03.2-2.9-2.83.1-0.8-3.00.4-0.40.70.7
Patch foraging total patch changes 0 sec1.82.88.4-2.0-2.90.32.3-2.61.6-0.12.10.31.1-1.01.62.1-1.7-2.02.30.41.4-0.11.3
Patch foraging total patch changes 12 sec5.57.114.7-3.4-3.83.13.6-3.33.7-0.23.30.22.4-2.53.13.4-3.2-0.43.3-0.01.1-0.71.1
Patch foraging total patch changes 18 sec10.413.428.6-5.3-4.93.34.9-4.84.7-0.94.61.03.2-3.64.44.8-4.1-1.84.20.62.2-1.31.3
Patch foraging total patch changes 24 sec6.47.917.7-4.2-4.23.24.0-3.63.30.73.3-0.93.1-3.32.63.1-3.10.03.4-0.90.20.1-0.1
Patch foraging total patch changes 6 sec5.48.117.2-4.1-3.92.64.0-3.53.6-0.03.7-0.13.0-3.32.93.5-3.3-1.13.4-0.11.3-0.60.5
Patch foraging time to switch 0 sec0.10.21.40.9-0.0-1.2-0.1-0.2-0.30.30.1-0.10.2-0.40.1-0.1-0.2-0.20.3-0.2-0.00.6-0.6
Patch foraging water rate 0 sec0.81.34.2-2.0-0.81.81.1-0.71.6-1.01.30.80.5-0.71.21.3-0.8-1.00.60.91.2-1.51.0
Patch foraging water rate 12 sec0.20.21.6-1.3-0.80.90.4-0.30.60.30.4-0.40.1-0.10.10.1-0.00.00.2-0.2-0.10.10.8
Patch foraging water rate 18 sec0.91.23.60.91.2-0.0-1.61.9-0.80.3-1.2-0.3-1.31.5-1.1-1.31.30.1-1.80.0-0.50.00.6
Patch foraging water rate 24 sec0.20.30.90.30.9-0.6-0.70.8-0.4-0.6-0.40.5-0.50.3-0.2-0.40.5-0.7-0.50.60.4-0.4-0.1
Patch foraging water rate 6 sec0.20.31.0-1.0-0.80.50.7-0.60.60.30.7-0.40.4-0.20.10.5-0.4-0.70.5-0.10.30.20.6
Seeking ratio, delayed vs. immediate footshock0.50.63.30.70.50.6-0.61.1-0.60.7-0.7-0.80.00.4-0.5-0.90.41.8-0.7-0.9-1.30.6-0.2
Distance traveled before self-admin2.42.67.5-2.6-0.92.71.2-0.72.4-1.71.61.40.5-1.02.32.0-0.9-0.50.91.31.5-2.01.3
Distance traveled after self-admin1.92.14.5-2.1-0.81.01.2-1.01.9-1.41.81.40.7-1.22.11.9-1.1-1.71.11.31.8-1.40.9
Extensor digitorum longus weight0.00.20.7-0.7-0.60.70.20.10.50.10.4-0.10.2-0.30.40.2-0.80.40.1-0.1-0.0-0.10.5
Bone: elastic displacement2.02.36.8-2.6-1.20.31.9-2.01.6-1.01.91.00.9-1.12.02.0-1.3-2.01.10.91.7-0.80.8
Bone: elastic work2.43.07.1-2.7-1.91.02.5-2.62.1-0.32.30.41.5-1.52.22.2-2.0-1.32.00.21.1-0.60.6
Bone: endosteal estimation1.53.310.20.80.60.0-0.61.1-1.52.6-1.1-2.81.0-0.7-1.9-2.10.13.2-0.3-2.6-3.11.9-2.4
Bone: endosteal perimeter1.02.04.91.40.8-0.6-1.11.2-1.71.5-1.5-1.8-0.10.5-2.1-1.90.92.2-0.6-1.5-2.11.3-1.1
Epididymis fat weight1.12.79.91.10.5-0.7-0.80.6-1.82.1-1.5-2.30.7-0.1-2.0-1.70.63.1-0.4-2.0-2.41.9-2.1
Delta time in closed arm before/after self-admin4.03.99.51.71.0-0.3-1.51.5-2.22.2-2.3-2.3-0.41.2-2.7-2.71.33.1-1.4-2.1-2.92.1-1.6
Delta time in open arm before/after self-admin2.12.13.81.61.8-0.9-1.71.6-0.6-1.9-1.01.9-1.81.5-0.2-0.41.5-1.1-1.71.91.3-1.50.9
Diff in mean of infusions in LGA sessions0.40.52.20.1-0.4-0.60.6-0.6-0.00.70.6-0.61.1-1.10.30.1-0.90.00.5-0.8-0.40.7-1.5
Delay discount exponential model param1.01.14.0-0.50.20.30.10.10.9-2.00.71.90.2-1.01.11.0-0.1-0.8-0.01.71.6-1.8-0.0
Extinction: sum of active levers before priming2.22.26.11.61.8-1.2-1.61.6-1.0-0.6-1.20.9-2.22.4-0.9-1.21.3-2.5-1.81.10.8-0.51.5
Active lever presses in extinction session 60.50.51.50.91.2-0.6-1.00.9-0.8-0.0-0.90.1-0.80.7-0.7-0.90.9-0.5-0.90.1-0.2-0.0-0.4
Bone: final force1.62.65.2-1.7-2.11.72.2-2.01.41.61.5-1.62.0-1.40.91.0-2.31.11.9-1.6-1.00.8-0.6
Bone: final moment1.32.14.5-1.7-1.81.62.0-1.81.31.51.3-1.61.8-1.20.80.9-2.11.21.7-1.5-0.90.6-0.4
Food consumed during 24 hour testing period0.50.62.2-0.2-0.40.60.10.3-0.41.2-0.0-1.30.6-0.6-0.5-0.8-0.41.5-0.1-1.2-1.30.9-0.8
Glucose0.20.31.0-1.0-0.1-0.10.4-0.60.4-0.20.70.50.2-0.20.20.7-0.2-1.00.10.40.7-0.60.6
Heart weight5.88.220.9-4.6-3.42.63.8-3.03.41.84.0-1.43.5-3.53.12.8-3.70.23.1-1.40.10.90.4
Delay discount hyperbolic model param1.11.24.6-0.40.40.4-0.10.30.8-2.20.52.10.0-0.81.00.90.1-0.8-0.21.81.7-2.00.1
Intermittent access intake day 1-15 change0.70.72.6-1.1-0.80.10.8-0.50.90.21.3-0.21.4-1.61.20.7-1.30.00.5-0.00.40.3-0.7
Intermittent access intake escalation0.70.71.9-1.0-0.6-0.50.7-0.60.30.91.0-0.91.4-1.30.50.3-1.00.40.5-0.6-0.21.1-1.1
Intermittent access intake escalation 20.30.30.8-0.8-0.40.00.4-0.30.10.70.4-0.70.9-0.80.10.1-0.50.50.2-0.5-0.30.7-0.8
Intermitt. access day 1 inactive lever presses0.00.00.40.1-0.6-0.1-0.0-0.1-0.1-0.0-0.1-0.1-0.0-0.1-0.1-0.0-0.00.50.0-0.1-0.20.00.0
Intermitt. access day 15 inactive lever presses0.10.10.7-0.4-0.40.90.30.00.40.10.2-0.20.4-0.40.20.2-0.30.6-0.3-0.1-0.2-0.00.0
Intermitt. access escalation Index0.20.20.6-0.3-0.10.20.5-0.60.6-0.40.50.4-0.00.20.60.6-0.4-0.20.50.30.4-0.50.7
Intermittent access day 1 total infusions1.11.33.41.91.60.3-1.51.8-0.5-0.8-1.00.8-1.71.7-0.5-0.81.0-0.4-1.10.80.2-0.91.3
Intermittent access day 15 total infusions0.30.41.81.01.2-0.2-1.01.3-0.4-0.0-0.4-0.0-0.40.5-0.3-0.70.30.3-0.70.1-0.20.10.1
Intermittent access terminal intake (last 3 days)0.30.42.51.60.8-0.0-0.81.2-0.1-0.6-0.20.5-0.40.30.0-0.30.4-0.1-0.40.50.3-0.40.2
Intermittent access total infusions1.11.34.01.92.0-0.2-1.51.9-0.6-1.0-0.91.0-1.31.3-0.4-0.80.9-0.5-1.10.90.4-0.80.8
Intermittent access day 1 locomotion0.40.41.00.50.70.5-0.70.8-0.0-0.8-0.50.8-0.90.8-0.1-0.20.5-0.3-0.50.70.4-0.91.0
Intermittent access day 15 total locomotion0.20.20.60.50.20.0-0.50.7-0.30.8-0.2-0.70.00.2-0.3-0.7-0.10.3-0.4-0.6-0.70.8-0.2
Intermittent access total locomotion0.10.10.80.50.5-0.4-0.40.6-0.10.00.10.1-0.10.00.1-0.3-0.2-0.9-0.30.20.20.10.1
Intermittent access standard deviation0.70.71.80.91.30.6-1.21.3-0.2-0.8-0.70.7-1.11.1-0.3-0.50.80.5-0.90.80.3-0.80.9
Left kidney weight1.02.95.4-2.3-2.12.11.8-1.31.52.31.6-2.01.7-1.31.20.5-2.31.81.6-2.0-1.51.30.3
Right kidney weight0.61.64.7-1.3-1.01.50.9-0.40.52.20.6-2.11.2-0.50.1-0.4-1.22.20.6-2.0-1.71.40.0
Cocaine induced anxiety1.92.24.8-2.1-1.50.31.9-1.81.21.11.9-1.12.2-2.11.21.2-1.9-0.21.7-1.0-0.21.0-1.0
Post-drug Anxiety3.64.08.1-2.7-2.61.52.5-2.01.91.52.4-1.52.8-2.81.71.7-2.70.82.2-1.4-0.51.1-1.0
Baseline Anxiety0.30.41.9-0.4-1.01.40.4-0.20.8-0.40.30.4-0.10.10.70.6-0.30.50.20.30.2-0.71.0
Tail length0.72.08.42.90.7-0.2-1.01.1-1.61.2-1.9-1.2-0.40.9-1.9-1.81.41.7-0.5-1.3-1.91.0-1.1
Length with tail0.83.07.90.1-2.10.91.4-1.5-0.22.50.1-2.51.8-1.2-0.7-0.5-1.02.81.6-2.7-2.52.0-1.5
Length without tail2.14.713.7-3.0-3.71.32.8-3.01.41.92.0-1.92.6-2.30.91.3-2.71.72.6-2.0-1.11.5-0.4
Times rat made contact with spout0.50.53.5-1.1-0.21.90.00.20.9-0.5-0.20.4-0.80.80.40.20.1-0.1-0.60.50.3-1.21.1
Lifetime Intake1.82.15.92.02.4-0.1-1.92.2-0.7-1.5-1.21.5-1.81.6-0.6-0.91.3-0.5-1.51.30.6-1.41.0
Liver weight, left0.30.41.0-0.4-0.40.6-0.40.5-0.21.0-0.6-0.9-0.50.7-0.3-0.70.11.0-0.2-0.8-1.00.90.4
Liver weight, right0.71.13.1-0.8-1.8-0.11.2-1.60.21.30.6-1.31.3-1.10.00.3-1.00.91.3-1.3-0.91.1-0.8
Locomotor activity2.23.58.8-3.0-2.82.22.3-2.02.40.72.5-0.51.5-1.22.11.9-2.7-0.11.8-0.30.50.22.0
Locomotor testing distance2.74.59.0-3.0-1.42.01.6-1.23.0-1.42.71.70.4-0.63.02.6-2.4-2.41.31.72.5-1.73.0
Locomotor testing rearing2.94.512.4-3.5-1.02.41.4-0.93.1-1.82.62.00.4-0.82.92.6-1.7-2.10.71.92.5-2.02.6
Locomotion in novel chamber1.01.33.1-1.2-1.70.31.7-1.80.61.21.0-1.01.5-1.30.70.9-1.10.31.4-1.1-0.50.8-1.0
Locomotion in novel chamber post-restriction1.51.85.5-2.3-1.61.41.6-1.51.21.41.4-1.21.4-1.01.01.0-1.51.01.6-1.2-0.70.80.4
Fecal boli incidents, locomotor time 11.11.23.5-0.4-0.8-1.30.7-0.8-0.31.90.8-1.61.5-1.1-0.2-0.2-1.00.40.7-1.4-0.91.9-1.2
Change in fecal boli incidents, locomotor task0.40.41.90.51.4-0.5-0.80.9-0.3-0.4-0.40.5-0.80.80.0-0.30.3-0.8-0.20.40.2-0.40.5
Time >=10cm from walls, locomotor time 10.90.92.5-0.5-1.6-0.41.2-1.60.70.21.2-0.21.5-1.20.71.0-1.00.21.4-0.30.30.4-0.3
Bouts of movement, locomotor time 11.11.23.50.7-0.2-1.90.7-0.8-0.51.60.7-1.41.5-1.1-0.4-0.1-1.2-0.10.9-1.3-0.71.8-1.8
Total resting periods, locomotor time 11.61.85.00.2-0.3-1.81.1-1.2-0.31.81.0-1.62.0-1.7-0.20.1-1.5-0.11.3-1.6-0.82.0-2.2
Rest time, locomotor task time 11.41.55.2-1.2-0.2-0.81.2-1.10.40.91.3-0.82.2-2.30.50.7-1.5-0.21.7-0.9-0.11.0-2.0
Distance moved, locomotor task time 11.51.66.7-0.6-1.01.80.0-0.11.2-1.70.21.6-1.41.21.20.80.0-0.8-0.21.61.3-1.92.6
Vertical activity count, locomotor time 11.61.76.30.1-0.51.6-0.40.41.0-1.9-0.11.8-1.71.40.90.50.4-0.9-0.81.81.4-2.12.5
Time >=10cm from walls, locomotor time 20.80.92.80.1-0.5-1.00.2-0.70.3-1.60.31.70.1-0.60.70.9-0.1-1.20.61.51.7-1.3-0.1
Bouts of movement, locomotor time 20.70.83.61.9-0.3-1.80.3-0.5-0.71.30.2-1.00.30.3-0.7-0.20.2-0.71.0-0.9-0.41.4-0.3
Total resting periods, locomotor time 20.60.61.71.3-0.4-1.30.6-0.8-0.21.20.5-0.90.60.0-0.30.2-0.1-0.71.3-0.8-0.31.2-0.2
Rest time, locomotor task time 21.31.63.9-1.4-0.6-0.11.5-1.30.81.51.5-1.32.0-1.80.70.8-1.3-0.11.8-1.2-0.41.3-1.1
Distance moved, locomotor task time 20.30.31.3-0.8-1.10.50.4-0.60.5-0.70.20.6-0.1-0.10.60.5-0.6-0.20.20.50.5-0.70.5
Vertical activity count, locomotor time 20.80.91.90.2-0.90.90.2-0.30.9-1.40.41.3-0.50.51.00.8-0.6-0.90.41.31.3-1.41.4
Light reinforcement 11.83.27.7-2.8-2.42.62.3-1.72.60.42.4-0.41.7-1.72.41.9-2.20.11.4-0.40.3-0.21.2
Light reinforcement 20.10.10.5-0.00.50.4-0.30.5-0.0-0.70.10.60.0-0.20.3-0.1-0.10.3-0.50.50.3-0.5-0.1
Bone: marrow area1.53.310.10.90.6-0.0-0.61.1-1.52.6-1.1-2.81.0-0.7-2.0-2.10.03.2-0.3-2.7-3.12.0-2.4
Bone: maximum diameter0.30.61.6-0.6-1.01.30.8-0.60.51.00.2-1.20.5-0.3-0.2-0.0-0.81.11.1-1.1-1.00.20.5
Bone: maximum force1.42.44.5-1.7-2.11.82.1-1.81.31.61.5-1.72.0-1.40.61.0-2.01.31.7-1.6-1.00.9-0.4
Bone: maximum moment1.11.93.3-1.6-1.81.71.8-1.61.11.51.2-1.61.7-1.10.50.8-1.81.41.5-1.4-1.00.7-0.2
Mean time between licks in bursts0.10.20.6-0.7-0.10.8-0.20.40.10.5-0.2-0.4-0.40.4-0.1-0.30.30.7-0.5-0.4-0.60.00.7
Mean num. licks in bursts0.70.92.21.20.6-0.7-0.70.5-1.31.1-1.2-0.9-0.81.5-1.5-1.20.90.3-0.8-0.9-1.00.30.0
Cd content in liver1.41.53.4-0.2-1.7-0.51.3-1.90.31.21.0-1.21.7-1.50.50.5-1.41.31.8-1.2-0.81.2-1.4
Co content in liver0.20.21.1-0.7-0.10.6-0.20.2-0.00.0-0.50.0-0.30.4-0.3-0.10.81.0-0.5-0.1-0.3-0.10.0
Cu content in liver1.01.36.2-0.3-2.5-0.61.6-2.30.40.81.3-0.61.0-0.70.11.2-0.4-0.22.0-0.50.20.70.0
Fe content in liver0.81.06.6-1.6-1.02.60.9-0.31.6-0.70.70.70.1-0.41.01.10.20.1-0.10.50.5-1.20.8
K content in liver1.01.02.41.41.1-1.1-1.31.1-1.3-0.5-1.30.4-1.11.1-1.1-0.91.60.2-1.20.50.0-0.3-0.3
Mg content in liver0.10.10.40.1-0.2-0.5-0.1-0.0-0.2-0.20.10.2-0.30.50.30.1-0.2-0.40.00.40.4-0.00.6
Mn content in liver0.91.13.50.3-0.10.1-0.20.4-0.91.7-0.5-1.70.40.2-1.1-1.00.21.9-0.1-1.6-1.71.3-0.8
Na content in liver0.40.41.7-0.7-0.91.30.4-0.3-0.10.6-0.4-0.7-0.10.4-0.7-0.30.81.1-0.4-0.8-0.90.6-0.2
Rb content in liver0.50.73.51.21.0-1.9-0.90.2-1.2-0.5-0.70.6-0.90.8-0.6-0.40.9-0.8-0.70.60.5-0.0-0.2
Se content in liver1.11.33.51.30.2-1.7-0.70.3-1.71.7-0.8-1.4-0.10.7-1.3-1.60.30.6-0.5-1.3-1.31.9-1.0
Sr content in liver0.40.32.0-1.4-0.11.40.30.10.50.10.2-0.40.3-0.30.30.1-0.50.9-0.8-0.3-0.40.20.2
Zn content in liver1.01.12.9-1.5-1.70.41.3-1.20.90.71.5-0.71.0-0.70.81.1-1.60.01.6-0.40.20.90.7
Bone: minimum diameter1.01.95.7-0.2-0.50.20.5-0.4-0.42.20.1-2.31.5-1.2-0.8-1.0-0.82.40.7-2.3-2.31.3-1.8
Time in familiar zone, hab. session 11.91.84.5-1.6-2.11.11.8-1.81.60.51.7-0.31.3-1.31.11.5-1.8-0.21.9-0.40.3-0.10.8
Time in novel zone, hab. session 10.70.71.80.91.2-1.3-0.80.5-0.6-1.1-0.51.1-0.80.80.2-0.20.5-1.3-0.51.11.0-0.6-0.0
Total zone transitions, hab. session 10.30.52.1-0.4-0.51.50.4-0.21.1-0.60.10.5-0.50.71.20.7-0.4-0.10.10.50.4-1.00.8
Total locomotion distance, hab. session 10.20.32.6-0.2-0.21.60.2-0.20.5-0.2-0.6-0.1-0.40.80.50.20.00.9-0.1-0.1-0.4-0.40.1
Locomotion velocity, hab. session 10.30.53.5-0.2-0.01.9-0.10.20.30.0-1.0-0.4-0.71.10.0-0.20.41.2-0.6-0.3-0.8-0.20.3
Time in familiar zone, hab. session 21.41.53.5-1.0-0.70.31.2-1.11.5-0.81.71.10.9-1.31.91.6-1.5-1.41.20.81.4-0.90.4
Time in novel zone, hab. session 20.60.61.80.80.7-0.7-0.90.8-1.10.3-1.0-0.5-0.60.8-1.3-1.01.30.3-0.7-0.2-0.50.4-0.2
Total zone transitions, hab. session 20.40.51.60.81.1-0.1-1.01.3-0.2-0.7-0.60.6-1.01.1-0.0-0.40.6-0.4-1.10.80.4-0.50.3
Total locomotion distance, hab. session 20.10.20.80.70.40.0-0.40.6-0.3-0.1-0.6-0.1-0.60.9-0.3-0.30.30.1-0.40.2-0.00.30.2
Locomotion velocity, hab. session 20.20.20.90.60.30.3-0.40.6-0.30.1-0.7-0.3-0.61.0-0.4-0.40.40.4-0.5-0.1-0.30.40.1
Novel to familiar place preference ratio2.12.16.52.22.5-2.6-1.81.4-1.9-0.9-1.70.9-0.80.6-1.2-1.21.6-0.5-1.40.80.3-0.3-1.7
Novelty place preference1.81.85.02.02.2-2.2-1.71.3-1.8-0.8-1.70.7-0.70.4-1.3-1.21.6-0.1-1.30.60.1-0.3-1.7
Time in novel zone, NPP test1.51.54.41.82.1-2.1-1.51.1-1.5-1.1-1.41.0-0.60.3-0.9-0.91.4-0.4-1.10.90.4-0.6-1.4
Total zone transitions, NPP test1.11.54.3-0.3-0.61.10.1-0.31.0-1.8-0.11.6-1.41.41.21.1-0.2-1.20.31.71.6-1.92.1
Total locomotion distance, NPP test0.20.30.7-0.1-0.70.70.5-0.70.5-0.7-0.10.3-0.50.80.60.7-0.2-0.50.50.60.6-0.40.7
Locomotion velocity, NPP test0.10.10.70.2-0.60.40.4-0.7-0.00.0-0.5-0.3-0.40.8-0.00.2-0.10.20.4-0.1-0.20.30.2
Intraocular pressure0.81.13.4-0.40.20.4-0.30.8-0.81.3-0.4-1.40.8-0.8-0.9-1.00.61.9-1.3-1.3-1.51.2-1.1
Delta distance traveled before/after self-admin0.50.64.71.10.5-2.2-0.30.2-0.80.40.0-0.10.4-0.5-0.4-0.5-0.0-1.0-0.2-0.3-0.00.7-1.3
Delta ambulatory time before/after self-admin1.01.05.91.91.0-2.4-1.00.7-1.50.4-0.7-0.3-0.10.0-1.0-1.10.7-0.1-0.8-0.3-0.40.8-1.3
Parametrial fat weight0.10.20.80.70.3-0.9-0.20.0-0.70.5-0.3-0.5-0.00.1-0.4-0.60.2-0.1-0.3-0.5-0.50.6-0.6
Pavlov. Cond. lever latency0.30.33.10.30.4-1.80.1-0.3-0.30.20.5-0.10.3-0.3-0.10.10.3-1.30.10.10.50.8-0.2
Pavlov. Cond. magazine entry latency0.60.82.6-0.1-0.11.6-0.00.8-0.21.2-0.5-1.30.2-0.0-1.2-0.80.81.3-0.7-1.2-1.30.7-0.2
Pavlov. Cond. change in total contacts0.50.62.20.4-0.21.0-0.10.4-0.40.9-0.7-1.00.2-0.1-1.0-0.80.31.5-0.3-1.1-1.40.6-0.8
Pavlov. Cond. index score0.50.66.4-0.6-0.52.50.10.60.50.2-0.4-0.5-0.1-0.1-0.4-0.10.11.4-0.4-0.5-0.8-0.30.3
Pavlov. Cond. latency score0.40.54.7-0.4-0.52.20.10.50.20.4-0.5-0.7-0.10.1-0.5-0.30.01.6-0.3-0.6-1.0-0.10.1
Pavlov. Cond. lever contacts0.60.73.8-0.0-0.01.9-0.50.9-0.0-0.2-1.20.1-1.11.2-0.5-0.50.41.2-0.70.0-0.6-0.70.8
Pavlov. Cond. magazine entry number0.91.15.30.60.8-2.3-0.7-0.1-0.3-1.4-0.01.6-0.90.90.80.30.0-1.60.11.51.6-0.70.5
Pavlov. Cond. intertrial magazine entries2.83.311.10.90.9-1.6-0.80.10.1-2.9-0.12.9-1.91.51.01.10.5-3.30.12.92.9-2.12.1
Pavlov. Cond. lever-magazine prob. diff.0.40.55.8-0.6-0.32.4-0.10.80.40.1-0.5-0.3-0.30.1-0.4-0.20.31.2-0.7-0.3-0.7-0.40.5
Pavlov. Cond. response bias0.70.99.8-1.0-0.53.10.30.70.70.3-0.3-0.6-0.0-0.1-0.3-0.10.31.5-0.6-0.6-0.9-0.40.5
Pavlov. Cond. lever latency0.70.92.20.71.4-0.5-1.21.4-0.80.6-1.0-0.7-0.40.5-0.9-1.50.91.1-1.4-0.5-1.00.9-0.4
Pavlov. Cond. magazine entry latency1.21.43.61.91.3-1.4-1.41.1-1.60.1-1.50.2-1.41.6-1.3-1.31.6-0.5-1.30.0-0.40.10.0
Pavlov. Cond. change in total contacts0.40.61.80.2-0.7-0.30.5-0.4-0.21.10.4-1.01.0-0.90.2-0.0-1.10.70.6-1.1-0.90.9-1.3
Pavlov. Cond. index score0.10.10.40.2-0.5-0.30.4-0.6-0.30.20.1-0.00.2-0.1-0.10.3-0.3-0.30.5-0.2-0.00.1-0.4
Pavlov. Cond. latency score0.10.10.50.5-0.4-0.70.3-0.5-0.50.3-0.0-0.20.2-0.1-0.30.1-0.2-0.20.5-0.3-0.20.3-0.7
Pavlov. Cond. lever contacts0.30.51.2-0.6-1.10.70.9-1.10.5-0.50.50.40.2-0.20.51.0-0.7-0.61.00.40.6-0.70.3
Pavlov. Cond. magazine entry number0.10.10.7-0.8-0.00.20.4-0.30.4-0.20.5-0.10.6-0.70.20.3-0.30.10.10.10.20.1-0.3
Pavlov. Cond. intertrial magazine entries0.50.72.9-1.7-0.40.50.8-0.41.10.31.4-0.20.8-0.91.10.9-1.3-0.50.6-0.00.40.20.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.2-0.6-0.40.4-0.6-0.30.30.1-0.20.3-0.2-0.10.2-0.4-0.20.5-0.3-0.10.2-0.6
Pavlov. Cond. response bias0.10.10.40.2-0.60.40.3-0.5-0.1-0.1-0.30.2-0.30.4-0.00.3-0.2-0.20.50.10.1-0.40.2
Time in closed arm before self-admin3.33.78.0-1.9-1.91.41.7-1.22.7-2.02.42.00.9-1.72.82.6-1.2-2.10.91.72.3-2.11.1
Time in closed arm after self-admin0.20.21.1-0.20.30.2-0.30.4-0.3-0.2-0.50.00.2-0.3-0.4-0.40.50.9-0.8-0.3-0.6-0.1-1.1
Time in open arm before self-admin3.63.911.00.7-0.0-0.6-0.30.1-1.93.3-1.3-3.20.60.1-2.2-2.20.32.8-0.1-3.0-3.13.1-1.9
Time in open arm after self-admin0.91.02.21.11.2-1.1-1.31.0-1.0-0.4-0.90.5-1.51.5-0.7-0.81.0-0.9-1.10.80.5-0.21.1
Bone: periosteal estimation1.02.06.2-0.7-1.01.20.9-0.50.12.20.2-2.41.5-1.2-0.7-0.6-0.92.51.0-2.3-2.21.2-1.2
Bone: periosteal perimeter0.81.44.0-0.6-1.20.70.9-0.80.21.90.4-2.01.4-0.9-0.5-0.2-1.01.91.1-1.8-1.71.3-0.5
Bone: post-yield work0.91.23.11.50.8-0.2-1.21.5-1.30.8-1.2-0.9-0.61.0-1.8-1.31.20.9-1.1-0.7-1.11.30.1
Progressive ratio test 1 active lever presses1.31.43.61.81.9-0.3-1.61.8-0.8-1.1-1.21.1-1.41.3-0.7-0.91.2-0.5-1.30.90.3-0.90.6
Progressive ratio test 1 breakpoint0.80.92.51.41.6-0.1-1.21.4-0.4-1.2-0.71.1-1.00.8-0.2-0.41.0-0.6-1.01.00.5-1.00.6
Progressive ratio test 1 inactive lever presses0.30.30.70.40.50.2-0.60.70.0-0.8-0.20.8-0.70.50.2-0.10.2-0.1-0.50.60.4-0.80.8
Progressive ratio test 2 active lever presses0.20.31.40.70.90.2-0.81.2-0.1-0.5-0.30.4-0.50.3-0.0-0.40.30.1-0.70.40.0-0.40.3
Progressive ratio test 2 breakpoint0.40.42.01.11.00.1-1.01.4-0.2-0.6-0.30.5-0.60.4-0.0-0.50.3-0.1-0.90.50.1-0.50.3
Progressive ratio test 2 inactive lever presses0.40.41.4-0.1-0.81.00.20.21.0-0.40.90.40.2-0.31.20.7-0.90.40.40.40.4-0.61.0
Incentive Sensitization - Responses0.20.21.01.00.2-0.2-0.60.8-0.2-0.6-0.20.5-0.60.5-0.1-0.30.3-0.4-0.50.50.2-0.40.2
Incentive Sensitization - Breakpoint0.20.20.91.00.1-0.2-0.60.8-0.2-0.5-0.20.4-0.60.5-0.0-0.30.2-0.4-0.40.50.2-0.40.2
Sum of active levers in priming session hrs 5-60.30.31.10.30.6-0.7-0.00.0-0.71.0-0.3-0.8-0.00.2-0.7-0.70.2-0.4-0.1-0.8-0.60.9-0.7
Progressive ratio1.21.43.9-0.8-2.00.81.5-1.40.61.30.9-1.21.6-1.70.50.6-1.21.11.6-1.2-0.81.0-1.1
Food seeking constrained by brief footshock0.50.61.5-0.5-1.20.10.9-0.80.8-0.21.00.30.5-0.60.81.1-0.7-1.21.10.40.8-0.30.6
Seeking ratio, punishment vs. effort0.70.92.00.61.2-0.6-0.90.9-0.3-1.1-0.51.1-1.31.4-0.3-0.20.8-1.4-1.01.10.9-0.81.3
Retroperitoneal fat weight0.31.13.8-0.4-0.4-0.30.5-0.5-0.61.3-0.1-1.51.5-1.5-0.9-0.2-0.31.90.3-1.4-1.21.0-1.6
Reaction time number correct1.21.74.8-0.10.50.5-0.70.80.8-2.2-0.12.1-1.51.11.10.50.6-1.7-0.92.01.7-2.11.3
Reaction time mean minus median0.30.41.3-0.9-0.1-0.20.4-0.10.30.40.9-0.41.0-1.11.00.4-1.1-0.00.2-0.4-0.10.4-0.6
Reaction time mean minus median AUC1.41.95.7-1.5-1.1-0.01.4-1.10.61.21.6-1.22.3-2.41.30.7-1.90.81.1-1.2-0.61.2-1.8
Reaction time num false alarms0.71.04.7-0.10.40.8-0.60.90.8-1.0-0.11.2-1.21.21.00.20.1-1.2-0.71.10.9-1.12.2
Reaction time num false alarms AUC0.91.24.90.21.00.7-0.91.20.5-1.1-0.41.3-1.61.60.8-0.00.2-1.2-0.91.20.9-1.22.2
Reaction time trials correct on left1.21.74.8-0.10.50.5-0.70.80.8-2.2-0.12.1-1.51.11.10.50.6-1.7-0.92.01.7-2.11.3
Reaction time trials on left1.21.74.70.00.60.4-0.80.90.7-2.2-0.12.1-1.51.11.10.40.7-1.7-1.02.01.6-2.01.3
Reaction time mean0.50.72.01.21.2-1.4-1.01.0-1.20.6-0.6-0.60.00.2-0.3-1.10.20.5-0.8-0.5-0.70.9-1.1
Reaction time mean AUC1.01.43.21.51.6-1.8-1.41.4-1.70.9-1.0-0.8-0.20.5-0.8-1.60.60.7-1.2-0.7-1.01.2-1.3
Median of all reaction times1.31.84.32.12.0-1.7-1.81.7-1.90.5-1.5-0.5-0.81.1-1.1-1.81.10.7-1.4-0.4-0.90.8-1.0
Reaction time omissions1.11.53.41.21.6-1.5-1.41.3-1.51.4-0.9-1.3-0.71.1-0.9-1.80.70.5-1.1-1.0-1.21.5-0.3
Reaction time false alarm rate0.30.41.30.70.9-0.1-0.80.9-0.30.1-0.60.1-0.91.1-0.1-0.60.2-0.2-0.60.1-0.10.01.1
Reaction time premature initiation rate1.11.56.2-0.1-0.1-0.80.4-0.80.8-1.80.91.9-0.60.21.11.3-0.8-2.50.71.72.0-1.31.3
Reaction time premature initiations1.92.79.3-0.3-0.1-0.40.2-0.61.2-2.51.02.6-1.00.61.71.6-0.6-3.10.52.42.6-2.11.8
Std. dev. reaction times0.20.31.3-0.50.1-0.50.3-0.20.20.40.9-0.20.9-0.81.20.3-1.0-0.10.3-0.30.00.3-0.7
Reaction time trials completed1.21.74.70.00.60.4-0.80.90.7-2.2-0.12.1-1.51.11.10.40.7-1.7-1.02.01.6-2.01.3
Reaction time trials AUC1.11.64.5-0.20.30.7-0.70.80.9-2.1-0.02.0-1.51.11.20.50.6-1.6-0.92.01.6-2.11.5
Run reversals in cocaine runway, females1.41.35.2-2.3-0.80.21.3-1.61.1-0.01.50.10.8-0.71.31.5-1.6-0.71.70.20.8-0.11.0
Run reversals in cocaine runway, males0.30.31.00.50.30.2-0.30.9-0.20.4-0.2-0.50.5-0.8-0.2-0.70.10.7-0.5-0.6-0.80.4-1.0
Latency to leave start box in cocaine runway0.50.61.70.40.31.2-0.70.9-0.30.3-1.1-0.2-1.11.3-0.9-0.80.90.7-0.7-0.3-0.8-0.10.5
Latency to leave start box in cocaine runway, F0.40.42.4-0.5-0.01.6-0.10.60.10.8-0.5-0.7-0.10.5-0.4-0.50.31.0-0.5-0.9-1.20.30.1
Latency to leave start box in cocaine runway, M2.01.95.91.10.80.2-1.40.8-0.3-1.8-1.41.7-2.42.3-0.7-0.41.4-0.7-0.61.71.1-1.71.8
Std. dev. time between licks in bursts3.84.59.2-3.0-2.92.12.9-2.82.70.12.7-0.22.3-2.52.32.4-2.60.42.7-0.30.5-0.50.0
Total sessions with >9 infusions1.21.33.91.12.0-0.7-1.21.1-0.6-1.7-0.91.6-1.31.1-0.4-0.31.1-1.0-0.91.41.0-1.40.5
Short access day 1 total inactive lever presses1.01.13.3-0.11.00.9-0.81.10.4-1.6-0.21.4-1.31.10.40.20.6-0.6-0.51.41.0-1.61.8
Short access day 10 total inactive lever presses0.10.10.5-0.7-0.70.60.2-0.30.4-0.10.30.10.1-0.10.40.5-0.30.50.30.20.2-0.20.6
Short access day 1 total infusions1.81.94.62.22.1-0.7-1.91.8-1.2-0.9-1.60.8-1.71.7-1.2-1.31.80.2-1.30.80.0-0.70.4
Short access day 10 total infusions3.13.510.73.33.1-1.0-2.52.6-1.7-1.1-2.01.1-2.12.1-1.5-1.82.0-0.3-2.21.00.1-0.80.3
Short access total infusions2.02.25.51.82.4-0.2-1.92.0-0.8-1.9-1.31.8-1.91.6-0.6-0.91.6-0.5-1.51.50.8-1.70.8
Short access day 1 locomotion0.40.40.9-0.3-0.3-0.20.5-0.70.5-0.80.50.80.4-0.60.60.9-0.3-0.50.80.70.9-0.8-0.1
Short access day 10 total locomotion0.30.41.00.51.0-0.5-0.90.9-0.4-0.5-0.40.5-0.60.5-0.3-0.50.4-0.7-0.80.60.4-0.30.1
Short access total locomotion0.40.41.50.51.2-0.5-0.90.8-0.3-0.8-0.40.9-0.70.6-0.1-0.30.6-0.6-0.70.80.7-0.70.3
One hour access (0.3 mA shock)0.91.02.70.91.60.2-1.21.60.0-1.3-0.31.3-1.10.90.2-0.20.4-0.7-1.01.20.9-1.21.4
Compulsive drug intake0.50.62.0-1.40.10.40.5-0.30.21.30.3-1.30.7-0.4-0.0-0.2-0.70.60.4-1.1-0.91.1-0.5
One hour access (shock baseline)0.81.02.21.01.10.4-1.01.40.0-1.4-0.41.4-1.11.00.1-0.00.7-0.3-0.81.30.8-1.41.5
Social response proportion0.80.93.30.20.0-1.80.4-0.7-0.51.60.6-1.20.9-0.40.4-0.1-1.3-0.30.9-1.1-0.51.4-1.2
Social responses1.21.53.9-1.1-1.60.11.5-1.61.40.51.8-0.11.0-0.81.81.5-2.0-1.11.5-0.00.8-0.10.4
Social time1.11.44.51.71.6-2.1-1.41.2-1.50.9-0.9-0.6-1.11.7-1.0-1.50.6-0.7-1.0-0.4-0.51.00.2
Soleus weight0.41.010.2-1.6-0.43.20.20.81.1-0.1-0.0-0.30.1-0.20.40.10.11.7-1.0-0.2-0.6-1.00.7
Bone: stiffness1.52.39.70.2-1.11.40.20.0-0.32.6-0.7-2.60.70.2-1.2-1.2-0.23.10.1-2.4-2.71.6-0.8
Tibialis anterior weight0.10.42.1-0.7-1.01.40.3-0.00.70.40.5-0.40.2-0.30.70.1-0.91.00.4-0.4-0.5-0.20.7
Time to tail flick, vehicle, before self-admin0.80.81.70.81.2-0.2-1.31.2-0.5-1.0-0.91.0-1.20.8-0.3-0.51.0-0.2-1.01.10.6-1.00.4
Time to tail flick, vehicle, after self-admin0.50.52.4-0.50.2-0.50.3-0.3-0.41.00.0-1.01.0-0.9-0.5-0.4-0.00.70.1-1.0-0.81.0-1.5
Time to tail flick, test, before self-admin2.52.46.3-1.1-0.40.80.2-0.21.5-2.50.92.5-0.80.11.61.6-0.1-2.0-0.12.32.3-2.52.2
Time to tail flick, test, after self-admin0.70.72.9-0.40.41.7-0.81.10.1-0.4-1.10.2-1.21.1-0.6-0.31.10.7-1.10.3-0.3-0.71.3
Delta time to tail flick, vehicle, before/after SA1.21.23.30.4-0.2-0.90.3-0.6-1.11.8-0.5-1.80.7-0.1-1.2-0.90.30.90.3-1.7-1.61.8-1.4
Delta time to tail flick, test, before/after SA1.81.66.00.50.31.1-0.91.2-1.01.4-1.6-1.6-0.61.0-1.6-1.41.02.4-0.8-1.3-2.01.1-0.3
Tibia length1.23.510.40.5-1.00.61.0-0.7-0.83.1-0.2-3.01.8-1.2-1.4-1.3-0.92.51.1-3.2-3.02.7-2.0
Ambulatory time before self-admin2.93.08.0-2.3-0.52.81.1-0.72.6-2.01.51.80.2-0.72.42.2-0.8-1.01.01.71.8-2.31.6
Ambulatory time after self-admin1.21.35.3-0.70.2-0.20.5-0.41.2-1.41.31.50.1-0.51.61.3-0.6-2.30.71.41.9-1.20.9
Bone: tissue strength0.70.71.81.00.8-1.3-0.70.5-1.30.6-0.9-0.6-0.30.6-0.9-1.00.90.5-0.6-0.5-0.70.9-0.5
Total heroin consumption0.30.31.20.80.4-0.2-0.60.6-0.40.0-0.70.0-1.01.1-0.5-0.40.5-0.8-0.90.10.1-0.20.6
Bone: trabecular number1.11.73.8-1.6-1.81.31.7-1.41.01.31.6-1.31.8-1.50.80.8-1.90.90.9-1.3-0.70.7-0.1
Bone: trabecular spacing0.50.71.90.31.1-0.2-1.31.4-0.4-0.8-0.80.6-1.31.0-0.3-0.70.7-0.4-1.00.80.4-0.60.6
Bone: trabecular thickness1.61.95.0-1.5-2.21.81.9-1.81.21.31.3-1.21.6-1.20.81.0-1.51.11.5-1.4-0.80.4-0.0
Bone: trabecular tissue density0.40.51.4-0.5-0.10.3-0.1-0.20.8-0.90.21.1-0.70.61.00.6-0.0-0.70.30.90.9-1.01.2
Water consumed over 24 hours0.60.73.2-1.10.21.8-0.41.10.8-0.50.00.7-0.70.50.5-0.10.2-0.2-1.30.60.4-1.31.1
Number of responses in last shaping day1.11.12.11.40.9-0.9-1.41.1-1.40.1-1.4-0.2-1.01.2-1.4-1.41.30.9-1.3-0.2-0.80.4-0.1