Hub : Genes

Fbln1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	gene expression	Fbln1	0.09	0.06	6.1e-06	0.06	0.04	0.06	0.06	2.4e-06	1.5e-04	3.4e-06	1.1e-06
2	NAcc	gene expression	Fbln1	0.15	0.07	2.6e-15	0.1	0.1	0.11	0.06	1.4e-15	4.9e-15	6.8e-16	3.8e-10
3	pVTA	gene expression	Fbln1	0.04	0.03	6.0e-04	0.04	0.03	0.04	0.03	5.7e-04	1.7e-03	6.1e-04	2.0e-03
4	RMTg	gene expression	Fbln1	0.2	0.15	4.8e-04	0.09	-0.01	0.11	0.01	1.8e-03	8.8e-01	7.6e-04	1.7e-01
5	BLA	gene expression	Fbln1	0.27	0.15	1.7e-06	0.07	0.09	0.07	0.07	2.2e-04	2.6e-05	1.5e-04	1.2e-04
6	RMTg	isoform ratio	XM_006242161.4	0.22	0.14	2.2e-03	0.04	0.03	0.05	0.04	3.3e-02	6.3e-02	2.1e-02	3.6e-02
7	NAcc	mRNA stability	Fbln1	0.02	0.01	4.7e-03	0.01	0.01	0.01	-0	3.4e-02	1.4e-02	9.4e-03	4.0e-01
8	Adipose	isoform ratio	NM_001127547.1	0.05	0.04	5.0e-03	0	0.01	0	0	9.7e-02	2.5e-02	1.1e-01	2.0e-01
9	Adipose	isoform ratio	XM_006242161.4	0.05	0.04	8.5e-03	0	0.01	0	0	1.3e-01	4.2e-02	1.2e-01	3.4e-01
10	PL	gene expression	Fbln1	0.13	0.08	2.7e-06	0.05	0.05	0.04	0.05	2.6e-06	7.7e-06	4.5e-05	4.2e-06
11	RMTg	isoform ratio	NM_001127547.1	0.22	0.14	2.6e-03	0.05	0.03	0.04	0.04	1.5e-02	5.5e-02	2.6e-02	2.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.8	1.4	2.8	-1.3	-1.3	-1.2	-1.7	-1.3	-1.0	1.5	-1.0	1.0	0.7	0.7
Area under the delay curve	1.9	2.2	4.5	-2.0	-1.5	-1.5	-1.2	-1.9	-0.2	1.2	-2.1	2.1	-0.2	-0.4
BMI with tail	1.6	5.7	11.5	2.0	2.9	2.8	2.2	1.9	3.4	-2.2	1.0	-0.9	-2.5	-3.0
BMI without tail	0.1	0.4	1.3	0.3	0.9	0.8	0.2	0.4	1.1	-0.3	0.4	-0.3	-0.6	-1.0
Body weight	1.1	4.8	8.4	2.4	2.9	2.9	1.7	2.1	2.4	-2.2	1.7	-1.6	-1.8	-1.8
Weight adjusted by age	0.4	0.6	1.0	1.0	0.9	0.7	0.8	1.0	0.4	-0.7	1.0	-1.0	-0.4	0.2
Bone surface	0.4	0.7	2.7	-0.8	-0.7	-0.6	-1.7	-1.1	-0.3	0.8	-0.8	0.8	0.2	0.1
Bone volume	0.3	0.6	1.4	-0.9	-0.8	-0.8	-1.2	-0.9	-0.6	0.9	-0.6	0.6	0.5	0.5
Breakpoint value in progressive ratio session	0.2	0.3	0.8	0.2	0.2	0.3	0.7	0.3	0.8	-0.2	0.1	-0.1	-0.7	-0.9
Number of licking bursts	0.5	0.9	2.3	-0.5	-0.6	-0.5	-1.2	-0.1	-1.3	1.1	0.4	-0.4	1.5	1.4
Context. condit. distance diff. score	2.1	2.5	5.8	2.1	1.7	1.9	1.9	1.5	1.3	-2.4	1.0	-1.0	-1.1	-0.9
Locomotion velocity, session 1	0.3	0.3	0.7	0.8	0.7	0.7	0.3	0.3	0.4	-0.8	0.5	-0.5	-0.3	-0.2
Locomotion distance, session 1	0.2	0.2	0.6	-0.1	-0.5	-0.5	-0.1	-0.3	-0.7	-0.1	-0.2	0.2	0.8	0.7
Locomotion velocity, session 2	1.8	2.1	3.1	1.7	1.6	1.6	1.7	1.7	1.2	-1.2	1.8	-1.7	-0.4	-0.6
Locomotion distance, session 2	0.2	0.2	0.4	-0.4	-0.3	-0.3	0.3	-0.5	0.5	0.2	-0.7	0.7	-0.4	-0.6
Locomotion velocity, session 3	2.9	3.3	5.7	2.4	1.7	1.9	2.2	2.1	0.2	-2.0	2.3	-2.3	0.3	0.5
Locomotion distance, session 3	0.8	0.9	2.0	0.4	-0.1	-0.1	1.0	0.8	-1.0	-0.2	1.3	-1.4	1.4	1.2
Stereotopy head waving bouts, day 3	1.6	1.8	3.3	1.6	1.7	1.8	0.8	1.0	1.6	-1.7	0.5	-0.4	-1.4	-1.3
Stereotopy head waving duration, day 3	3.1	3.7	7.1	2.5	2.6	2.7	1.5	2.1	1.8	-2.0	1.4	-1.4	-1.3	-1.2
Locomotion velocity, session 7	2.3	2.5	4.6	2.1	1.7	1.7	1.8	2.1	0.5	-1.5	1.9	-1.9	0.2	0.2
Locomotion distance, session 7	0.1	0.1	0.3	0.6	0.2	0.2	0.2	0.4	-0.1	-0.4	0.3	-0.3	0.3	0.2
Stereotopy head waving bouts, day 7	2.8	3.2	6.4	2.0	1.7	1.9	2.5	2.2	0.6	-1.5	2.3	-2.3	0.1	-0.1
Stereotopy head waving duration, day 7	1.5	1.8	3.7	1.5	1.2	1.4	1.9	1.7	0.3	-0.9	1.8	-1.8	0.2	0.1
Locomotion velocity, session 8	5.6	6.8	11.1	2.9	2.9	3.0	3.3	2.7	2.5	-2.8	2.3	-2.2	-1.5	-1.8
Locomotion distance, session 8	1.1	1.6	4.1	1.5	1.1	1.2	2.0	1.2	1.0	-1.8	1.0	-1.0	-0.7	-0.7
Degree of sensitization distance	1.3	1.3	3.8	0.5	0.9	0.8	-0.1	-0.2	1.7	-1.0	-1.0	1.0	-1.9	-1.7
Degree of sensitization stereotypy	1.6	1.7	3.7	1.3	1.1	1.2	1.9	1.7	0.3	-0.9	1.9	-1.9	0.4	0.1
Conditioned locomotion	0.1	0.1	0.3	0.5	0.2	0.3	0.1	0.5	-0.0	-0.4	0.3	-0.3	0.1	0.3
Cocaine response after cond. corrected	0.6	0.8	1.7	-0.4	-0.4	-0.5	-1.3	-0.1	-1.1	1.2	0.4	-0.5	1.3	1.1
Cocaine response after cond. not corrected	1.2	1.4	3.9	-0.5	-0.6	-0.7	-1.0	0.1	-1.7	1.4	1.0	-1.0	2.0	1.7
Cocaine response before conditioning	0.2	0.3	0.7	-0.3	-0.6	-0.7	0.4	0.1	-0.7	0.1	0.3	-0.3	0.8	0.8
Saline control response	0.5	0.6	1.8	-0.5	-0.9	-0.9	-0.0	-0.2	-1.4	0.5	0.3	-0.3	1.1	1.2
Bone: connectivity density	0.4	0.7	2.2	-0.8	-0.7	-0.7	-1.5	-1.0	-0.6	1.0	-0.6	0.6	0.3	0.5
Bone: cortical apparent density	0.8	1.1	2.4	-0.9	-1.1	-1.0	-1.1	-1.4	-0.6	0.5	-1.5	1.5	-0.3	0.4
Bone: cortical area	0.8	1.2	2.5	1.3	1.4	1.3	1.0	1.6	0.6	-0.6	1.3	-1.2	-0.0	-0.2
Bone: cortical porosity	0.1	0.1	0.4	0.2	0.3	0.3	0.5	0.6	0.2	0.1	0.3	-0.3	0.2	-0.1
Bone: cortical porosity	0.3	0.3	0.7	0.4	0.6	0.5	0.9	0.7	0.6	-0.3	0.4	-0.4	-0.1	-0.5
Bone: cortical thickness	0.1	0.1	0.3	-0.1	0.1	0.1	-0.4	-0.1	0.0	0.2	-0.6	0.6	-0.3	-0.0
Bone: cortical thickness	0.8	1.0	2.0	1.1	1.4	1.4	0.4	0.8	1.2	-0.9	-0.2	0.2	-1.2	-0.9
Bone: cortical tissue density	0.6	0.9	2.1	-0.8	-0.9	-0.8	-1.0	-1.3	-0.4	0.4	-1.5	1.4	-0.4	0.3
Condit. Reinf. active minus inactive responses	0.7	0.8	1.5	-1.0	-0.9	-0.8	-1.0	-1.2	-0.2	0.8	-1.2	1.2	0.1	0.1
Condit. Reinf. active-inactive response ratio	0.9	1.0	2.0	-1.0	-0.9	-0.8	-1.3	-1.4	-0.4	0.7	-1.4	1.4	0.0	0.1
Condit. Reinf. active responses	1.1	1.3	2.3	-1.4	-1.4	-1.4	-1.3	-1.5	-0.7	1.1	-1.2	1.2	0.5	0.5
Condit. Reinf. inactive responses	0.4	0.4	1.1	-0.8	-1.0	-1.1	-0.6	-0.8	-0.7	0.4	-0.3	0.2	0.4	0.4
Incentive salience index mean	0.4	0.4	1.2	-0.6	-0.6	-0.6	-1.1	-0.7	-0.6	0.7	-0.6	0.5	0.6	0.6
Condit. Reinf. lever presses	0.2	0.3	0.8	0.3	0.0	-0.0	-0.7	0.3	-0.7	0.2	0.5	-0.5	0.9	0.9
Condit. Reinf. active minus inactive responses	0.3	0.4	1.8	0.2	0.3	0.2	0.5	0.2	1.1	-0.6	-0.0	0.1	-0.8	-1.3
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.2	-0.2	-0.1	-0.1	-0.2	-0.1	0.1	0.3	0.1	-0.1	0.1	-0.4
Condit. Reinf. active responses	1.3	1.8	4.2	1.0	1.1	0.9	1.4	0.9	2.1	-1.6	0.3	-0.2	-1.7	-2.1
Condit. Reinf. inactive responses	2.1	2.7	4.9	1.6	1.8	1.6	1.6	1.3	2.2	-2.0	0.5	-0.4	-1.9	-1.8
Condit. Reinf. lever presses	0.8	1.1	1.8	0.9	1.1	1.0	1.1	1.0	1.3	-1.0	0.8	-0.8	-0.9	-1.3
Condit. Reinf. lever reinforcers received	0.8	1.2	3.2	0.6	0.7	0.5	1.2	0.6	1.8	-1.2	0.1	-0.1	-1.4	-1.8
Conditioned reinforcement - actives	0.1	0.2	0.5	-0.2	-0.3	-0.3	-0.5	-0.7	-0.1	-0.1	-0.6	0.6	-0.4	-0.2
Conditioned reinforcement - inactives	0.1	0.1	0.4	0.1	0.0	0.0	0.1	-0.1	0.3	-0.5	-0.2	0.2	-0.5	-0.6
Conditioned locomotion	0.4	0.5	1.4	0.8	0.7	0.6	0.3	0.8	-0.0	-0.3	1.2	-1.2	0.3	0.3
Patch foraging indifference point 0 sec	0.4	0.8	2.8	-1.0	-0.7	-0.8	-1.1	-0.5	-0.9	1.7	-0.0	0.0	0.9	0.6
Patch foraging indifference point AUC	0.2	0.3	0.6	-0.6	-0.8	-0.7	0.1	-0.7	0.0	-0.2	-0.8	0.8	-0.4	-0.4
Delay disc. indifference point, 0s delay	0.1	0.1	0.3	0.1	0.2	0.3	-0.2	-0.2	0.3	-0.0	-0.3	0.4	-0.5	-0.6
Delay disc. indifference point, 16s delay	2.8	3.1	5.0	-2.2	-1.8	-1.7	-2.0	-2.2	-0.8	1.9	-2.2	2.2	0.4	0.2
Delay disc. indifference point, 2s delay	0.6	0.6	1.7	-0.9	-0.6	-0.6	-0.7	-1.0	0.0	0.5	-1.3	1.3	-0.3	-0.4
Delay disc. indifference point, 24s delay	0.2	0.2	0.5	-0.7	-0.1	-0.2	0.1	-0.2	0.6	0.5	-0.5	0.5	-0.5	-0.6
Delay disc. indifference point, 4s delay	2.5	2.7	6.4	-2.0	-1.5	-1.4	-1.1	-2.3	0.1	1.0	-2.5	2.5	-0.8	-0.7
Delay disc. indifference point, 8s delay	1.5	1.8	3.6	-1.7	-1.4	-1.4	-0.9	-1.7	0.0	0.9	-1.9	1.9	-0.4	-0.7
Indifference point function ln k	0.8	1.5	3.0	1.6	1.6	1.5	0.4	1.5	-0.0	-0.5	1.7	-1.7	0.3	0.6
Indifference point function log k	0.8	1.5	3.0	1.6	1.6	1.5	0.4	1.5	-0.0	-0.5	1.7	-1.7	0.3	0.6
Patch foraging total patch changes 0 sec	0.5	1.0	3.1	-1.1	-0.8	-1.0	-1.1	-0.5	-1.2	1.8	0.1	-0.1	1.1	0.9
Patch foraging total patch changes 12 sec	0.1	0.1	0.4	0.0	0.0	-0.0	0.4	0.1	0.6	-0.4	-0.3	0.3	-0.5	-0.6
Patch foraging total patch changes 18 sec	0.5	0.8	1.3	-1.1	-1.1	-1.1	-0.9	-0.7	-1.0	1.0	-0.5	0.5	1.0	0.7
Patch foraging total patch changes 24 sec	0.3	0.5	1.1	-0.1	-0.2	-0.2	0.4	0.5	-0.9	0.5	1.0	-1.1	1.0	1.0
Patch foraging total patch changes 6 sec	0.7	1.1	2.5	-1.6	-1.1	-1.2	-1.1	-1.1	-0.6	1.5	-0.8	0.8	0.5	0.1
Patch foraging time to switch 0 sec	0.2	0.4	2.2	0.4	0.3	0.2	1.5	0.8	0.7	-0.6	0.2	-0.2	-0.2	-0.4
Patch foraging water rate 0 sec	0.1	0.2	0.9	0.1	0.4	0.4	0.1	0.5	-0.1	0.4	1.0	-0.9	0.2	0.0
Patch foraging water rate 12 sec	0.6	1.3	2.9	-0.4	-0.4	-0.5	-0.7	0.1	-1.6	1.5	1.4	-1.4	1.7	1.4
Patch foraging water rate 18 sec	0.2	0.3	1.0	-0.7	-0.5	-0.6	-0.6	-0.4	-0.7	1.0	0.3	-0.3	0.5	0.4
Patch foraging water rate 24 sec	0.1	0.1	0.3	0.2	0.4	0.2	0.2	0.2	0.3	-0.0	0.6	-0.6	-0.3	-0.4
Patch foraging water rate 6 sec	0.4	0.6	1.8	-0.5	-0.5	-0.5	-0.4	-0.3	-1.4	0.7	0.3	-0.3	1.0	1.3
Seeking ratio, delayed vs. immediate footshock	0.9	1.1	2.4	-1.3	-1.2	-1.4	-0.9	-0.8	-1.0	1.5	-0.2	0.2	1.0	0.9
Distance traveled before self-admin	0.1	0.2	0.6	0.1	-0.3	-0.2	-0.5	0.0	-0.8	-0.2	0.1	-0.1	0.7	0.6
Distance traveled after self-admin	0.4	0.5	1.2	0.4	0.0	0.2	0.3	0.9	-0.5	0.2	1.1	-1.1	0.9	0.9
Extensor digitorum longus weight	0.3	1.2	2.6	1.2	1.1	1.0	1.1	1.4	0.7	-0.5	1.6	-1.6	-0.1	-0.3
Bone: elastic displacement	0.3	0.4	1.2	0.1	-0.2	-0.2	0.7	0.5	-0.5	0.0	1.1	-1.1	0.6	0.4
Bone: elastic work	2.8	3.7	7.2	1.9	1.9	1.8	2.7	2.5	1.4	-1.5	2.4	-2.3	-0.4	-1.0
Bone: endosteal estimation	2.2	4.8	7.6	2.5	2.4	2.4	2.5	2.7	1.5	-1.8	2.8	-2.7	-0.3	-0.9
Bone: endosteal perimeter	2.8	5.9	12.8	2.6	2.4	2.4	2.7	3.4	0.8	-1.1	3.6	-3.6	0.8	0.1
Epididymis fat weight	0.6	1.9	4.9	0.9	1.0	1.0	1.4	0.3	2.2	-1.4	-0.5	0.5	-2.2	-2.0
Delta time in closed arm before/after self-admin	0.4	0.3	1.1	-0.6	-0.2	-0.1	-0.7	-0.5	0.2	0.5	-1.0	1.0	-0.4	-0.1
Delta time in open arm before/after self-admin	1.5	1.5	4.3	1.1	0.0	0.1	1.1	1.1	-0.9	-0.9	2.1	-2.1	1.3	0.9
Diff in mean of infusions in LGA sessions	0.6	0.7	1.5	0.2	0.4	0.6	-0.6	-0.5	1.0	-0.4	-1.1	1.1	-1.2	-1.1
Delay discount exponential model param	2.1	2.3	4.9	2.1	1.5	1.5	1.1	2.0	0.1	-1.2	2.2	-2.2	0.3	0.5
Extinction: sum of active levers before priming	0.8	0.8	2.5	-0.5	-0.0	-0.1	0.1	-0.7	1.4	-0.1	-1.0	1.0	-1.6	-1.4
Active lever presses in extinction session 6	1.1	1.1	3.1	0.8	1.1	1.3	-0.4	0.2	1.5	-0.6	-0.2	0.3	-1.4	-1.8
Bone: final force	0.7	1.1	2.7	0.6	1.1	1.1	0.3	0.5	1.6	-1.0	-0.4	0.4	-1.6	-1.6
Bone: final moment	0.9	1.5	3.6	0.7	1.3	1.3	0.4	0.5	1.9	-1.1	-0.4	0.5	-1.8	-1.8
Food consumed during 24 hour testing period	1.8	2.5	4.3	2.1	2.1	1.9	1.4	1.7	1.5	-1.8	1.0	-1.0	-1.2	-1.0
Glucose	0.3	0.5	1.1	-0.4	-0.5	-0.4	-1.0	-0.6	-0.7	0.7	-1.1	1.0	0.2	0.8
Heart weight	2.0	3.1	6.5	1.6	2.2	2.3	1.1	1.1	2.5	-1.6	0.4	-0.3	-2.2	-2.2
Delay discount hyperbolic model param	2.1	2.3	5.0	2.0	1.6	1.5	1.1	2.0	0.1	-1.2	2.2	-2.2	0.3	0.5
Intermittent access intake day 1-15 change	0.1	0.3	0.9	0.2	-0.1	-0.2	-0.3	0.3	-0.6	0.3	0.5	-0.5	1.0	0.8
Intermittent access intake escalation	0.2	0.3	1.1	0.0	-0.3	-0.3	-0.4	0.1	-0.9	0.4	0.4	-0.4	1.1	0.9
Intermittent access intake escalation 2	0.4	0.4	0.9	-0.7	-0.8	-0.8	-0.4	-0.3	-0.7	0.9	-0.3	0.3	1.0	0.6
Intermitt. access day 1 inactive lever presses	0.2	0.7	1.4	0.7	0.5	0.4	1.1	0.4	1.1	-1.1	-0.4	0.4	-1.1	-1.2
Intermitt. access day 15 inactive lever presses	0.4	0.7	1.9	0.5	0.2	0.2	-0.9	-0.4	1.1	-0.7	-1.0	1.0	-1.1	-1.4
Intermitt. access escalation Index	0.7	1.0	4.9	-0.7	-0.7	-0.7	-2.2	-1.3	-0.9	0.9	-0.9	0.8	0.5	0.4
Intermittent access day 1 total infusions	0.5	0.8	2.2	1.5	1.0	0.9	-0.1	0.7	0.2	-1.4	1.0	-1.0	-0.5	-0.0
Intermittent access day 15 total infusions	0.4	0.7	1.1	1.0	0.3	0.3	-0.8	0.5	-1.0	-0.5	1.0	-1.1	0.8	1.0
Intermittent access terminal intake (last 3 days)	0.5	0.6	1.7	1.3	0.7	0.7	-0.4	0.8	-0.3	-0.8	1.0	-1.1	0.4	0.4
Intermittent access total infusions	0.6	0.7	1.9	1.4	0.7	0.8	0.1	0.9	-0.2	-1.1	1.1	-1.1	0.2	0.4
Intermittent access day 1 locomotion	0.2	0.2	1.1	0.6	0.2	0.3	-1.0	-0.1	-0.5	-0.3	0.3	-0.3	0.2	0.4
Intermittent access day 15 total locomotion	0.8	1.4	3.6	1.9	1.2	1.2	0.2	1.3	0.0	-1.2	1.7	-1.7	0.1	0.2
Intermittent access total locomotion	1.2	1.4	3.3	1.8	1.1	1.1	1.1	1.4	0.5	-1.5	1.5	-1.5	-0.4	-0.0
Intermittent access standard deviation	0.4	0.8	1.6	1.3	1.0	1.0	0.8	0.9	1.0	-1.2	0.3	-0.2	-0.8	-0.7
Left kidney weight	9.9	46.2	68.2	8.0	8.3	8.3	6.8	6.8	6.9	-7.7	5.3	-5.1	-5.3	-5.0
Right kidney weight	10.5	47.7	67.7	7.7	8.2	8.2	7.2	6.4	7.8	-7.9	4.3	-4.1	-6.5	-6.0
Cocaine induced anxiety	1.0	1.4	4.7	0.3	0.7	0.5	1.0	-0.0	1.9	-0.9	-0.7	0.8	-2.2	-1.6
Post-drug Anxiety	1.0	1.0	2.6	-0.8	-0.4	-0.5	0.0	-1.0	1.1	0.2	-1.6	1.6	-1.3	-1.2
Baseline Anxiety	1.3	1.5	3.4	-0.7	-1.0	-0.8	-1.8	-0.8	-1.8	1.3	-0.2	0.2	1.8	1.3
Tail length	0.6	2.3	5.3	-1.1	-1.5	-1.5	-1.9	-1.2	-2.3	1.4	-0.2	0.1	1.8	2.1
Length with tail	0.1	0.5	1.0	1.0	0.7	0.8	0.1	0.7	-0.2	-0.6	1.0	-1.0	0.1	0.6
Length without tail	0.9	3.0	5.8	1.7	2.1	2.1	1.2	1.1	2.4	-1.7	0.4	-0.4	-2.3	-2.1
Times rat made contact with spout	0.6	0.6	1.6	1.0	1.0	0.9	-0.2	-0.0	0.7	-1.3	-0.3	0.3	-1.2	-0.7
Lifetime Intake	0.8	1.0	2.1	1.5	0.9	0.9	0.6	1.2	0.0	-1.3	1.3	-1.3	0.0	0.2
Liver weight, left	0.7	1.2	3.2	1.7	1.4	1.3	0.3	0.9	0.7	-1.8	0.7	-0.7	-0.7	-0.5
Liver weight, right	0.5	0.8	3.2	1.5	1.0	1.0	-0.2	0.5	0.2	-1.8	0.5	-0.5	-0.5	0.0
Locomotor activity	1.6	2.5	4.9	2.2	2.1	2.0	0.4	2.0	0.9	-1.4	1.8	-1.8	-0.3	-0.4
Locomotor testing distance	0.2	0.3	1.2	0.4	0.5	0.4	-1.1	0.5	-0.4	0.3	0.5	-0.5	0.7	0.6
Locomotor testing rearing	0.4	0.8	1.5	1.2	1.1	1.0	0.1	1.2	-0.0	-0.8	1.1	-1.1	0.3	0.6
Locomotion in novel chamber	1.2	1.6	3.9	0.2	-0.4	-0.3	-1.5	0.2	-1.9	0.6	1.3	-1.3	2.0	1.8
Locomotion in novel chamber post-restriction	0.0	0.1	0.1	-0.3	-0.3	-0.2	0.0	0.1	-0.1	0.3	0.3	-0.3	0.3	0.1
Fecal boli incidents, locomotor time 1	0.4	0.6	1.5	0.7	0.6	0.6	1.2	0.6	0.8	-0.9	0.7	-0.7	-0.7	-0.6
Change in fecal boli incidents, locomotor task	0.5	0.5	1.4	-0.3	-0.3	-0.3	-0.1	0.3	-1.0	0.6	0.8	-0.8	1.2	1.1
Time >=10cm from walls, locomotor time 1	0.6	0.6	1.4	0.5	1.0	1.1	0.9	0.7	1.2	-0.5	0.3	-0.3	-0.9	-0.6
Bouts of movement, locomotor time 1	0.5	0.5	1.8	-0.3	0.7	0.6	-0.0	-0.1	1.2	-0.0	-0.6	0.6	-1.3	-1.0
Total resting periods, locomotor time 1	0.8	0.9	2.6	-0.5	0.5	0.4	-0.4	-0.5	1.4	0.2	-1.2	1.2	-1.6	-1.2
Rest time, locomotor task time 1	0.8	1.0	2.5	0.6	1.3	1.2	0.6	0.6	1.6	-0.7	0.3	-0.3	-1.2	-1.3
Distance moved, locomotor task time 1	0.0	0.1	0.2	0.3	0.1	0.2	0.2	0.4	-0.2	-0.1	0.3	-0.3	0.1	0.4
Vertical activity count, locomotor time 1	0.1	0.3	0.5	-0.6	-0.5	-0.5	-0.6	-0.3	-0.5	0.7	-0.4	0.4	0.5	0.5
Time >=10cm from walls, locomotor time 2	0.1	0.2	0.8	-0.1	0.0	-0.0	-0.3	0.2	-0.3	0.9	0.2	-0.2	0.6	0.6
Bouts of movement, locomotor time 2	0.8	1.3	2.8	-1.2	-0.3	-0.2	0.5	-0.8	1.2	0.3	-1.7	1.7	-1.7	-1.5
Total resting periods, locomotor time 2	1.0	1.7	3.5	-1.3	-0.4	-0.3	0.3	-1.1	1.3	0.3	-1.9	1.9	-1.9	-1.7
Rest time, locomotor task time 2	1.2	1.5	3.6	-1.7	-1.4	-1.3	-1.3	-1.9	-0.5	0.7	-1.3	1.3	-0.3	-0.2
Distance moved, locomotor task time 2	2.4	2.8	5.9	2.2	1.6	1.5	1.9	2.4	0.3	-1.1	2.2	-2.2	0.5	0.6
Vertical activity count, locomotor time 2	1.7	2.3	5.0	1.9	1.4	1.4	1.9	2.2	0.2	-0.7	2.0	-2.0	0.8	0.7
Light reinforcement 1	0.8	1.8	5.7	1.2	0.8	0.5	1.0	1.8	-0.6	-0.2	2.4	-2.4	1.0	1.0
Light reinforcement 2	1.5	2.3	4.8	1.7	1.8	1.6	1.3	2.2	0.6	-1.0	2.1	-2.1	-0.0	-0.0
Bone: marrow area	2.1	4.6	7.2	2.4	2.4	2.3	2.5	2.6	1.6	-1.8	2.7	-2.6	-0.4	-1.0
Bone: maximum diameter	3.9	7.3	11.9	3.1	3.2	3.2	2.9	3.4	2.0	-2.0	3.2	-3.1	-0.6	-1.2
Bone: maximum force	1.0	1.8	3.8	1.1	1.6	1.6	1.3	1.2	2.0	-1.2	0.3	-0.2	-1.5	-1.7
Bone: maximum moment	1.3	2.3	5.0	1.2	1.8	1.8	1.3	1.2	2.2	-1.4	0.2	-0.2	-1.8	-2.0
Mean time between licks in bursts	0.7	1.7	3.7	-0.9	-1.1	-0.9	-1.5	-0.7	-1.9	1.6	-0.2	0.2	1.9	1.7
Mean num. licks in bursts	1.5	2.4	6.8	1.2	1.3	1.2	1.3	0.1	1.8	-2.2	-0.7	0.8	-2.6	-2.0
Cd content in liver	0.2	0.3	0.6	0.7	0.6	0.6	0.3	0.7	-0.1	-0.4	0.7	-0.7	0.2	0.3
Co content in liver	0.1	0.1	0.4	-0.0	0.0	-0.1	-0.4	0.0	-0.6	0.2	0.3	-0.3	0.6	0.6
Cu content in liver	4.8	5.8	12.7	-3.3	-3.0	-3.0	-1.7	-2.2	-2.3	3.6	-1.1	1.0	2.0	1.4
Fe content in liver	0.2	0.2	0.6	-0.1	0.3	0.3	0.8	0.6	0.5	0.1	0.4	-0.4	-0.2	-0.5
K content in liver	0.1	0.1	0.7	0.0	-0.2	-0.2	0.9	-0.1	0.2	-0.3	0.1	-0.1	-0.1	-0.3
Mg content in liver	0.1	0.1	0.3	-0.5	-0.3	-0.3	0.0	-0.5	0.1	0.4	-0.5	0.5	-0.2	-0.5
Mn content in liver	0.4	0.5	1.1	0.9	0.7	0.7	0.8	0.7	0.0	-1.0	0.8	-0.8	0.1	0.2
Na content in liver	0.6	0.6	1.4	-1.1	-1.2	-1.1	0.2	-0.5	-0.6	1.2	-0.3	0.3	0.9	0.4
Rb content in liver	0.6	0.7	1.2	-1.0	-0.4	-0.4	-0.8	-1.0	0.2	1.0	-1.1	1.1	-0.6	-0.8
Se content in liver	0.2	0.3	0.6	-0.4	-0.5	-0.5	-0.8	-0.4	-0.6	0.4	0.1	-0.1	0.7	0.8
Sr content in liver	0.2	0.2	0.7	-0.3	-0.5	-0.4	-0.8	-0.6	-0.3	-0.1	-0.5	0.5	0.3	0.4
Zn content in liver	0.1	0.1	0.4	0.5	0.3	0.3	0.4	0.2	-0.4	-0.7	0.4	-0.4	-0.0	0.2
Bone: minimum diameter	1.7	3.2	7.8	1.8	1.5	1.4	1.6	2.5	-0.2	-0.5	2.8	-2.8	1.4	0.8
Time in familiar zone, hab. session 1	0.6	0.6	1.3	0.8	0.9	0.8	0.7	1.1	0.4	-0.5	1.1	-1.1	0.1	-0.3
Time in novel zone, hab. session 1	0.1	0.1	0.4	-0.3	-0.3	-0.2	-0.7	-0.3	-0.4	0.2	-0.3	0.3	0.3	0.3
Total zone transitions, hab. session 1	1.0	1.4	2.4	-1.4	-1.5	-1.5	-1.1	-1.5	-1.1	0.8	-1.3	1.3	0.6	0.5
Total locomotion distance, hab. session 1	0.1	0.2	0.4	0.4	0.1	0.1	0.3	0.3	-0.4	-0.7	0.5	-0.6	0.3	0.3
Locomotion velocity, hab. session 1	0.1	0.2	0.5	0.5	0.1	0.2	0.5	0.3	-0.3	-0.7	0.6	-0.6	0.2	0.1
Time in familiar zone, hab. session 2	0.4	0.4	2.0	-0.2	-0.4	-0.5	-1.4	-0.4	-0.9	0.4	0.1	-0.1	0.8	0.6
Time in novel zone, hab. session 2	0.1	0.1	0.2	-0.4	-0.2	-0.1	0.4	-0.3	0.1	-0.0	-0.4	0.4	-0.4	-0.1
Total zone transitions, hab. session 2	0.2	0.2	0.7	0.3	0.4	0.3	0.6	0.2	0.8	-0.5	-0.0	0.1	-0.5	-0.8
Total locomotion distance, hab. session 2	0.2	0.3	0.7	0.5	0.4	0.4	0.8	0.6	0.2	-0.4	0.7	-0.7	0.1	-0.2
Locomotion velocity, hab. session 2	0.2	0.2	0.6	0.5	0.4	0.4	0.8	0.5	0.3	-0.4	0.5	-0.5	-0.0	-0.3
Novel to familiar place preference ratio	0.0	0.0	0.1	-0.1	-0.3	-0.2	0.3	-0.3	-0.3	-0.2	-0.0	0.0	-0.1	0.2
Novelty place preference	0.1	0.1	0.3	0.3	0.1	0.1	0.5	0.1	-0.4	-0.4	0.4	-0.4	0.0	0.5
Time in novel zone, NPP test	0.1	0.1	0.3	0.3	0.1	0.1	0.4	0.1	-0.4	-0.5	0.5	-0.5	0.1	0.4
Total zone transitions, NPP test	0.4	0.6	1.3	-0.9	-1.1	-1.1	-0.3	-1.1	-0.5	0.3	-0.8	0.8	0.1	0.1
Total locomotion distance, NPP test	0.2	0.2	0.9	-0.1	-0.3	-0.2	1.0	0.3	-0.3	-0.1	0.8	-0.8	0.5	0.2
Locomotion velocity, NPP test	0.2	0.2	0.7	-0.1	-0.4	-0.4	0.9	0.2	-0.5	0.2	0.6	-0.6	0.6	0.4
Intraocular pressure	0.1	0.1	0.3	0.5	0.1	0.1	-0.0	0.2	-0.3	-0.4	0.3	-0.4	0.3	0.4
Delta distance traveled before/after self-admin	0.7	0.8	2.1	0.9	0.6	0.7	0.9	1.1	0.1	-0.2	1.5	-1.4	0.4	0.6
Delta ambulatory time before/after self-admin	0.3	0.4	1.3	0.5	0.5	0.5	0.3	0.8	0.1	0.1	1.2	-1.1	0.4	0.4
Parametrial fat weight	0.4	0.8	1.5	-1.0	-1.0	-1.1	-1.0	-0.7	-1.2	0.8	-0.5	0.5	1.0	0.9
Pavlov. Cond. lever latency	0.5	0.6	1.8	-0.1	0.2	0.3	0.5	-0.3	1.1	-0.6	-0.6	0.7	-1.3	-1.3
Pavlov. Cond. magazine entry latency	1.1	1.4	2.2	-1.3	-1.2	-1.3	-1.5	-1.1	-0.9	1.5	-1.0	1.0	0.9	0.8
Pavlov. Cond. change in total contacts	0.9	1.0	3.6	-1.1	-0.7	-0.8	-1.9	-0.8	-0.6	1.5	-0.7	0.7	0.8	0.6
Pavlov. Cond. index score	0.6	0.7	1.3	-0.8	-0.9	-1.0	-1.1	-0.6	-0.9	1.1	-0.5	0.5	0.9	0.9
Pavlov. Cond. latency score	0.4	0.5	1.1	-0.5	-0.6	-0.7	-0.7	-0.2	-0.9	1.0	-0.0	0.0	1.1	1.0
Pavlov. Cond. lever contacts	0.7	0.8	2.3	-0.2	-0.4	-0.5	-1.0	0.1	-1.3	0.9	0.4	-0.5	1.5	1.5
Pavlov. Cond. magazine entry number	1.2	1.5	3.3	1.4	1.2	1.3	1.8	1.3	0.9	-1.5	1.2	-1.2	-0.7	-0.7
Pavlov. Cond. intertrial magazine entries	1.1	1.3	2.5	-1.6	-1.3	-1.3	-1.4	-1.6	-0.7	1.3	-1.0	1.0	0.3	0.1
Pavlov. Cond. lever-magazine prob. diff.	0.8	0.9	1.7	-0.9	-1.0	-1.1	-1.2	-0.7	-1.0	1.3	-0.6	0.6	1.0	1.0
Pavlov. Cond. response bias	1.0	1.3	3.6	-1.1	-1.0	-1.1	-1.9	-0.9	-1.1	1.5	-0.7	0.7	1.1	1.0
Pavlov. Cond. lever latency	0.4	0.6	1.2	-0.5	-0.7	-0.6	-0.9	-0.8	-1.0	0.6	-0.6	0.6	0.6	1.1
Pavlov. Cond. magazine entry latency	0.7	0.8	1.9	-1.4	-0.7	-0.7	0.2	-0.8	0.7	0.9	-1.1	1.1	-0.6	-1.0
Pavlov. Cond. change in total contacts	0.6	1.0	3.3	0.0	0.6	0.5	1.4	0.5	1.7	-0.3	-0.1	0.1	-1.1	-1.8
Pavlov. Cond. index score	0.2	0.3	1.5	-0.4	0.1	-0.1	0.7	0.0	1.0	0.0	-0.3	0.3	-0.7	-1.2
Pavlov. Cond. latency score	0.3	0.3	1.5	-0.4	0.2	0.1	0.7	0.1	1.0	0.1	-0.1	0.2	-0.7	-1.2
Pavlov. Cond. lever contacts	0.3	0.4	1.4	0.1	0.5	0.3	0.7	0.4	1.0	-0.5	0.2	-0.2	-0.7	-1.2
Pavlov. Cond. magazine entry number	0.2	0.3	0.9	0.3	-0.0	-0.0	-0.9	-0.1	-0.8	0.0	0.2	-0.2	0.6	1.0
Pavlov. Cond. intertrial magazine entries	0.6	0.8	2.4	0.4	0.7	0.7	0.5	0.2	1.5	-0.9	-0.5	0.6	-1.6	-1.4
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	1.2	-0.4	0.1	-0.0	0.8	0.1	0.9	0.0	-0.1	0.1	-0.6	-1.1
Pavlov. Cond. response bias	0.2	0.3	1.5	-0.4	0.1	-0.1	0.4	-0.1	1.0	-0.1	-0.3	0.4	-0.7	-1.2
Time in closed arm before self-admin	2.2	2.8	4.5	-1.9	-2.0	-2.1	-1.5	-1.5	-1.9	2.1	-0.8	0.8	1.6	1.4
Time in closed arm after self-admin	1.3	1.4	2.6	-1.0	-1.1	-1.1	-1.5	-0.6	-1.6	1.5	-0.4	0.4	1.4	1.5
Time in open arm before self-admin	0.4	0.4	1.1	0.6	0.7	0.7	1.0	0.9	0.5	-0.6	0.6	-0.6	-0.4	-0.2
Time in open arm after self-admin	1.4	1.5	5.4	1.1	0.7	0.7	2.3	1.3	0.6	-1.3	1.6	-1.6	-0.3	-0.4
Bone: periosteal estimation	2.0	4.3	7.3	2.5	2.4	2.4	2.1	2.7	1.4	-1.6	2.5	-2.5	-0.2	-0.8
Bone: periosteal perimeter	2.9	5.0	10.8	2.6	2.4	2.4	2.0	3.1	0.6	-1.0	3.3	-3.3	0.8	0.3
Bone: post-yield work	1.1	1.6	4.2	-0.8	-0.2	-0.2	-0.8	-1.3	1.4	-0.1	-2.0	2.1	-1.7	-1.4
Progressive ratio test 1 active lever presses	0.2	0.3	2.1	0.3	-0.0	-0.0	-1.4	-0.6	-0.3	-0.4	-0.3	0.3	-0.3	0.1
Progressive ratio test 1 breakpoint	0.3	0.4	2.6	0.1	-0.1	-0.1	-1.6	-0.7	-0.4	-0.3	-0.5	0.5	-0.2	0.2
Progressive ratio test 1 inactive lever presses	0.3	0.5	1.8	1.2	0.8	0.8	0.1	0.5	0.3	-1.4	0.2	-0.2	-0.4	-0.2
Progressive ratio test 2 active lever presses	0.7	0.8	2.6	0.7	0.6	0.5	0.7	-0.1	1.1	-1.3	-0.3	0.4	-1.6	-1.2
Progressive ratio test 2 breakpoint	0.5	0.6	2.1	0.7	0.5	0.4	0.6	-0.0	0.9	-1.2	-0.3	0.3	-1.4	-1.0
Progressive ratio test 2 inactive lever presses	0.1	0.2	1.2	0.7	0.1	-0.1	0.3	0.1	0.3	-1.1	0.0	-0.0	-0.6	-0.4
Incentive Sensitization - Responses	0.7	1.0	3.8	0.5	0.5	0.3	1.0	-0.2	1.4	-1.1	-0.6	0.6	-1.9	-1.5
Incentive Sensitization - Breakpoint	1.0	1.3	4.2	0.6	0.7	0.4	1.2	-0.0	1.6	-1.2	-0.5	0.6	-2.1	-1.6
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.7	0.1	0.1	0.2	0.9	0.3	0.7	-0.2	0.2	-0.2	-0.5	-0.4
Progressive ratio	0.2	0.3	0.9	-0.7	-0.2	-0.2	-0.3	-0.7	0.2	0.4	-1.0	1.0	-0.4	-0.1
Food seeking constrained by brief footshock	0.3	0.3	0.8	0.4	0.9	0.9	0.5	0.7	0.7	-0.3	0.4	-0.4	-0.4	-0.4
Seeking ratio, punishment vs. effort	0.4	0.6	1.0	0.7	0.8	0.8	0.8	1.0	0.8	-0.4	0.7	-0.7	-0.4	-0.9
Retroperitoneal fat weight	1.7	7.1	11.9	2.7	3.0	2.9	2.7	2.4	3.5	-2.9	1.4	-1.4	-2.7	-2.9
Reaction time number correct	0.2	0.4	1.0	-0.6	-0.4	-0.5	0.0	0.0	-0.9	0.7	0.6	-0.6	0.8	1.0
Reaction time mean minus median	0.1	0.2	0.8	-0.7	-0.7	-0.9	0.3	-0.3	-0.5	0.3	0.1	-0.1	0.3	0.3
Reaction time mean minus median AUC	0.1	0.4	2.0	0.2	0.1	-0.1	1.4	0.5	0.2	-0.6	0.7	-0.7	-0.3	-0.1
Reaction time num false alarms	0.4	0.6	2.1	0.1	-0.2	-0.2	-0.4	0.3	-1.2	0.2	0.8	-0.8	1.4	1.3
Reaction time num false alarms AUC	0.4	0.6	1.6	0.4	-0.1	-0.1	-0.3	0.3	-1.1	-0.2	0.8	-0.9	1.3	1.3
Reaction time trials correct on left	0.2	0.4	1.0	-0.6	-0.4	-0.5	0.0	0.0	-0.9	0.7	0.6	-0.6	0.8	1.0
Reaction time trials on left	0.2	0.4	1.0	-0.6	-0.5	-0.5	-0.0	0.0	-0.9	0.7	0.5	-0.5	0.8	1.0
Reaction time mean	0.8	1.3	2.9	-1.6	-1.6	-1.7	-0.0	-1.4	-0.0	0.7	-1.4	1.4	-0.2	-0.3
Reaction time mean AUC	0.8	1.3	2.9	-1.5	-1.6	-1.7	0.1	-1.4	-0.0	0.5	-1.4	1.4	-0.3	-0.3
Median of all reaction times	1.2	1.7	3.2	-1.7	-1.7	-1.7	-0.3	-1.6	0.2	0.8	-1.8	1.8	-0.4	-0.5
Reaction time omissions	0.5	0.7	1.3	-1.1	-1.0	-1.1	-0.9	-1.2	-0.5	0.6	-1.0	1.0	0.1	0.3
Reaction time false alarm rate	0.2	0.2	0.5	0.7	0.2	0.2	-0.4	0.3	-0.5	-0.4	0.4	-0.5	0.7	0.6
Reaction time premature initiation rate	1.3	1.9	5.2	0.1	0.9	0.8	1.7	0.3	2.2	-0.8	-0.6	0.7	-2.2	-2.3
Reaction time premature initiations	0.5	0.9	2.6	-0.2	0.5	0.4	1.6	0.2	1.4	-0.4	-0.3	0.4	-1.6	-1.5
Std. dev. reaction times	0.3	0.6	1.9	-1.1	-1.2	-1.4	0.2	-0.9	-0.4	0.3	-0.6	0.6	0.0	0.1
Reaction time trials completed	0.2	0.4	1.0	-0.6	-0.5	-0.5	-0.0	0.0	-0.9	0.7	0.5	-0.5	0.8	1.0
Reaction time trials AUC	0.1	0.3	0.6	-0.4	-0.2	-0.3	0.1	0.2	-0.7	0.6	0.6	-0.6	0.6	0.8
Run reversals in cocaine runway, females	1.9	1.9	6.2	-0.6	-1.0	-1.1	-2.5	-0.8	-1.9	1.4	-0.1	0.1	1.7	1.7
Run reversals in cocaine runway, males	0.9	0.9	2.4	1.2	0.8	0.8	0.7	1.2	0.1	-1.0	1.6	-1.6	0.3	0.0
Latency to leave start box in cocaine runway	1.0	1.1	2.8	1.3	1.6	1.7	0.7	1.3	0.7	-1.0	0.9	-0.9	-0.3	-0.3
Latency to leave start box in cocaine runway, F	0.7	0.8	2.5	1.0	1.5	1.6	0.1	0.9	0.7	-0.8	0.5	-0.5	-0.5	-0.2
Latency to leave start box in cocaine runway, M	0.5	0.5	1.2	0.8	0.5	0.6	1.1	0.9	0.3	-0.6	0.9	-0.9	0.2	-0.2
Std. dev. time between licks in bursts	0.1	0.2	0.6	-0.7	-0.4	-0.3	-0.2	-0.2	0.5	0.8	-0.2	0.2	-0.0	-0.4
Total sessions with >9 infusions	2.0	2.5	3.6	1.8	1.7	1.8	1.8	1.9	1.1	-1.8	1.6	-1.6	-0.9	-0.5
Short access day 1 total inactive lever presses	1.0	1.3	2.6	1.2	1.3	1.2	0.5	0.8	1.6	-1.2	0.7	-0.6	-1.2	-1.5
Short access day 10 total inactive lever presses	0.5	1.2	3.2	1.0	0.9	1.0	1.8	1.2	1.2	-1.2	0.8	-0.7	-0.7	-1.1
Short access day 1 total infusions	0.5	0.6	1.4	1.2	0.9	1.0	0.3	0.9	0.4	-1.0	0.9	-0.9	-0.3	-0.3
Short access day 10 total infusions	0.4	0.5	1.2	1.1	0.9	1.0	0.0	0.8	0.3	-1.0	0.7	-0.7	-0.3	-0.2
Short access total infusions	1.0	1.3	2.3	1.5	1.3	1.3	0.9	1.3	0.8	-1.5	1.1	-1.1	-0.7	-0.5
Short access day 1 locomotion	0.1	0.1	0.3	0.5	0.3	0.4	0.6	0.4	0.2	-0.5	0.2	-0.2	-0.3	-0.0
Short access day 10 total locomotion	0.2	0.3	0.9	0.9	0.2	0.3	-0.7	0.2	-0.7	-0.5	0.2	-0.2	0.6	1.0
Short access total locomotion	0.2	0.3	0.6	0.8	0.4	0.3	0.2	0.7	-0.2	-0.4	0.6	-0.6	0.3	0.6
One hour access (0.3 mA shock)	0.8	0.9	1.8	1.4	0.7	0.6	1.1	1.2	-0.0	-1.0	1.3	-1.3	-0.1	0.4
Compulsive drug intake	0.3	0.4	1.1	0.3	0.4	0.3	0.7	0.2	1.0	-0.6	0.0	0.0	-1.0	-0.8
One hour access (shock baseline)	0.4	0.6	1.3	1.1	0.4	0.2	0.1	0.8	-0.9	-0.6	1.1	-1.1	0.8	0.9
Social response proportion	0.7	0.7	1.4	1.2	1.2	1.2	0.3	1.1	0.5	-0.8	0.9	-0.9	-0.2	0.0
Social responses	0.9	1.2	2.6	1.4	1.2	1.0	0.3	1.4	-0.1	-0.9	1.6	-1.6	0.3	0.6
Social time	1.4	1.8	6.6	-1.1	-1.0	-1.1	-2.6	-1.5	-1.2	0.9	-1.5	1.4	0.4	1.2
Soleus weight	0.5	1.4	4.0	0.5	0.7	0.6	0.4	-0.2	2.0	-1.1	-0.9	0.9	-2.0	-1.9
Bone: stiffness	0.2	0.4	1.2	-0.2	0.5	0.5	0.4	0.4	1.1	0.1	-0.6	0.6	-0.7	-1.0
Tibialis anterior weight	0.0	0.1	0.5	-0.6	-0.3	-0.4	-0.3	-0.4	0.2	0.7	-0.2	0.2	-0.0	-0.2
Time to tail flick, vehicle, before self-admin	0.6	0.6	1.3	0.0	0.2	0.3	-1.1	-1.0	0.3	-0.4	-1.0	1.0	-1.1	-0.7
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.4	-0.3	-0.2	-0.2	-0.6	-0.5	-0.2	0.2	-0.1	0.1	-0.1	-0.4
Time to tail flick, test, before self-admin	0.6	0.6	1.8	1.3	0.9	1.0	-0.2	1.0	0.1	-1.0	0.7	-0.7	0.2	0.2
Time to tail flick, test, after self-admin	0.3	0.3	1.1	-0.6	-0.3	-0.2	-1.1	-0.4	-0.4	1.0	-0.4	0.4	0.5	-0.1
Delta time to tail flick, vehicle, before/after SA	1.0	0.9	2.1	0.7	1.0	0.9	1.1	0.9	1.4	-0.8	0.5	-0.5	-0.8	-1.5
Delta time to tail flick, test, before/after SA	1.3	1.4	3.4	-1.9	-1.4	-1.4	-0.4	-1.3	-0.8	1.8	-0.9	0.9	0.5	0.1
Tibia length	0.0	0.1	0.2	-0.3	-0.0	-0.1	0.4	-0.1	0.3	0.2	0.1	-0.1	-0.3	-0.3
Ambulatory time before self-admin	0.2	0.3	0.9	0.3	-0.4	-0.3	-0.3	0.1	-0.9	-0.5	0.4	-0.4	0.8	0.8
Ambulatory time after self-admin	0.7	0.8	2.1	-0.4	-0.8	-0.7	-0.9	-0.1	-1.3	0.8	0.6	-0.6	1.5	1.3
Bone: tissue strength	0.5	0.5	1.0	-1.0	-0.5	-0.6	-0.4	-0.8	0.5	0.4	-0.9	0.9	-0.7	-0.9
Total heroin consumption	1.4	1.7	3.9	0.8	0.9	0.9	1.8	0.7	2.0	-1.1	0.2	-0.1	-1.9	-1.8
Bone: trabecular number	1.2	2.0	3.3	-1.3	-1.5	-1.5	-1.8	-1.3	-1.6	1.6	-0.7	0.7	1.3	1.5
Bone: trabecular spacing	3.8	5.0	8.1	2.4	2.7	2.6	2.8	2.6	2.3	-2.0	2.0	-2.0	-1.2	-1.6
Bone: trabecular thickness	0.2	0.3	0.6	-0.4	-0.6	-0.5	-0.4	-0.4	-0.8	0.5	-0.3	0.3	0.5	0.8
Bone: trabecular tissue density	0.3	0.5	1.1	-0.8	-1.0	-1.0	0.2	-0.8	0.2	0.0	-0.9	0.9	-0.3	-0.5
Water consumed over 24 hours	0.7	0.9	1.6	1.3	1.2	1.1	0.8	1.0	0.8	-1.1	0.8	-0.7	-0.8	-0.5
Number of responses in last shaping day	0.3	0.3	1.0	-0.4	-0.3	-0.3	-1.0	-0.5	0.1	0.5	-1.0	0.9	-0.1	0.0