Fam98c

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio XM_063283450.1 0.02 0.02 2.1e-03 0.01 0.01 0.01 0.01 9.7e-03 3.6e-02 1.2e-02 1.0e-02
2 NAcc alternative polyA NM_001198584.1 0.02 0.02 1.2e-04 0.02 0.02 0.01 0.01 4.0e-04 6.3e-04 6.3e-03 1.9e-03
3 NAcc alternative TSS XM_006228717.4 0.01 0.01 5.0e-03 0.01 0.01 0.01 0.01 1.5e-02 1.7e-02 2.7e-02 3.5e-02
4 NAcc isoform ratio XM_063283450.1 0.02 0.02 3.4e-04 0.02 0.02 0.02 0.02 8.8e-04 1.0e-03 4.2e-04 4.3e-04
5 NAcc isoform ratio XM_006228717.4 0.04 0.03 4.7e-08 0.04 0.05 0.05 0.04 4.3e-07 1.1e-07 6.3e-08 4.6e-07
6 Adipose gene expression Fam98c 0.23 0.11 0.0e+00 0.16 0.15 0.16 0.16 2.8e-17 1.5e-16 3.7e-17 5.7e-17
7 Liver gene expression Fam98c 0.29 0.15 0.0e+00 0.12 0.12 0.12 0.12 1.1e-13 2.0e-13 6.0e-13 1.7e-13
8 PL gene expression Fam98c 0.46 0.12 0.0e+00 0.55 0.31 0.56 0.34 5.0e-72 1.2e-34 6.2e-73 1.1e-38
9 NAcc gene expression Fam98c 0.51 0.04 0.0e+00 0.7 0.47 0.71 0.2 1.6e-151 2.1e-79 9.0e-154 3.2e-30
10 BLA alternative TSS XM_006228717.4 0.04 0.03 9.6e-03 0.03 0.02 0.01 -0 1.0e-02 2.0e-02 5.8e-02 5.0e-01
11 BLA alternative TSS NM_001198584.1 0.04 0.03 9.9e-03 0.03 0.02 0.01 -0 1.1e-02 2.2e-02 6.1e-02 5.2e-01
12 BLA gene expression Fam98c 0.48 0.2 0.0e+00 0.47 0.46 0.45 0.21 1.2e-27 3.3e-27 3.2e-26 1.7e-11
13 Eye gene expression Fam98c 0.78 0.14 5.9e-03 0.11 0.03 0.05 0.09 1.0e-02 1.2e-01 5.7e-02 2.0e-02
14 pVTA gene expression Fam98c 0.25 0.12 9.2e-15 0.18 0 0.17 0.04 2.6e-14 3.4e-01 8.2e-14 4.1e-04
15 NAcc alternative TSS NM_001198584.1 0.03 0.03 1.2e-04 0.02 0.03 0.02 0.02 2.4e-04 9.5e-05 3.2e-04 2.2e-04
16 LHb gene expression Fam98c 0.39 0.18 1.2e-07 0.18 0.22 0.18 0.22 4.9e-05 7.2e-06 4.8e-05 5.7e-06
17 IL gene expression Fam98c 0.62 0.17 2.0e-14 0.44 0.44 0.44 0.45 9.3e-12 6.0e-12 7.3e-12 2.9e-12
18 NAcc alternative TSS NM_001198584.1 0.02 0.02 2.1e-03 0.01 0.01 0.01 0.01 7.6e-03 3.1e-03 1.4e-02 9.6e-03
19 IC gene expression Fam98c 0.7 0.11 0.0e+00 0.42 0.1 0.46 0.21 6.4e-19 5.0e-05 3.0e-21 4.6e-09
20 OFC gene expression Fam98c 0.74 0.14 1.4e-14 0.32 0.42 0.39 0.41 1.7e-08 3.7e-11 2.5e-10 9.2e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.00.00.10.10.3-0.10.1-0.20.00.1-0.10.0-0.20.2-0.2-0.1-0.10.1-0.3-0.30.1-0.1-0.1
Area under the delay curve0.20.31.8-1.3-1.30.7-0.40.40.30.20.20.10.1-0.10.1-0.0-0.0-0.00.10.10.1-0.4-0.7
BMI with tail0.10.20.40.60.5-0.60.5-0.6-0.4-0.4-0.5-0.4-0.60.6-0.6-0.4-0.30.4-0.4-0.40.4-0.2-0.2
BMI without tail0.61.82.2-1.2-1.21.3-1.31.31.51.51.41.51.2-1.21.21.31.4-1.41.31.3-1.41.31.3
Body weight2.410.612.2-3.1-3.13.3-3.33.23.53.43.43.53.2-3.23.23.23.3-3.33.13.1-3.33.23.1
Weight adjusted by age0.00.00.10.3-0.0-0.20.0-0.0-0.0-0.1-0.0-0.0-0.00.0-0.0-0.10.0-0.00.10.1-0.1-0.00.3
Bone surface0.30.61.2-0.7-0.60.9-0.80.81.01.10.91.00.7-0.70.70.70.9-0.80.60.6-0.80.70.7
Bone volume0.40.71.2-0.8-0.70.9-0.90.91.01.10.91.00.8-0.80.80.80.9-0.80.70.7-0.80.80.8
Breakpoint value in progressive ratio session1.51.84.2-2.0-1.61.4-1.41.41.21.31.31.21.3-1.31.31.41.2-1.31.31.3-1.21.10.8
Number of licking bursts1.72.73.71.81.8-1.91.7-1.6-1.9-1.9-1.7-1.8-1.51.5-1.5-1.6-1.61.6-1.5-1.51.5-1.6-1.3
Context. condit. distance diff. score0.10.10.20.40.4-0.40.3-0.4-0.3-0.2-0.3-0.4-0.40.4-0.4-0.3-0.40.3-0.2-0.20.3-0.4-0.4
Locomotion velocity, session 12.42.63.51.00.8-1.41.5-1.4-1.8-1.9-1.7-1.8-1.61.6-1.6-1.5-1.71.7-1.6-1.61.7-1.9-1.8
Locomotion distance, session 10.70.91.4-1.2-1.11.0-0.90.90.90.90.90.91.0-1.01.01.11.0-1.01.01.0-1.00.90.9
Locomotion velocity, session 20.50.51.00.91.0-0.90.8-0.9-0.7-0.7-0.7-0.7-0.70.7-0.7-0.6-0.60.7-0.7-0.70.7-0.5-0.5
Locomotion distance, session 20.50.71.81.21.3-1.11.0-1.1-0.9-0.8-0.8-0.7-0.80.8-0.8-0.6-0.60.7-0.8-0.80.7-0.5-0.3
Locomotion velocity, session 30.20.20.60.80.8-0.60.5-0.5-0.5-0.4-0.4-0.4-0.30.3-0.3-0.3-0.30.4-0.3-0.30.3-0.3-0.2
Locomotion distance, session 36.46.97.9-2.1-2.12.5-2.72.62.72.82.72.72.6-2.62.62.72.8-2.72.72.7-2.72.72.7
Stereotopy head waving bouts, day 30.50.62.01.41.2-1.00.8-0.9-0.8-0.7-0.7-0.8-0.50.5-0.5-0.6-0.70.6-0.5-0.50.6-0.5-0.3
Stereotopy head waving duration, day 32.53.03.92.01.8-1.81.8-1.8-1.7-1.7-1.7-1.7-1.61.6-1.6-1.7-1.71.7-1.7-1.71.7-1.6-1.5
Locomotion velocity, session 70.00.00.10.00.10.1-0.10.10.30.20.10.2-0.00.0-0.00.10.0-0.10.00.0-0.10.10.0
Locomotion distance, session 70.10.10.3-0.4-0.30.4-0.40.30.50.50.40.50.3-0.30.30.40.4-0.40.30.3-0.40.40.4
Stereotopy head waving bouts, day 70.20.30.91.00.8-0.60.4-0.5-0.5-0.4-0.5-0.5-0.50.5-0.5-0.6-0.60.4-0.4-0.40.4-0.3-0.1
Stereotopy head waving duration, day 70.91.01.71.31.2-1.21.0-1.0-1.1-1.0-1.0-1.0-1.01.0-1.0-1.1-1.11.0-0.9-0.90.9-0.9-0.7
Locomotion velocity, session 83.34.05.62.42.3-2.32.1-2.3-2.0-1.9-2.0-2.0-2.02.0-2.0-1.9-2.01.9-1.8-1.81.9-1.8-1.5
Locomotion distance, session 80.40.61.00.80.9-1.00.9-1.0-0.8-0.8-0.8-0.9-0.80.8-0.8-0.8-0.80.8-0.7-0.70.7-0.7-0.6
Degree of sensitization distance3.53.64.41.31.3-1.71.9-1.9-1.8-1.9-1.9-1.9-2.02.0-2.0-1.9-2.02.0-2.0-2.02.0-2.0-2.1
Degree of sensitization stereotypy0.00.00.20.40.3-0.1-0.10.1-0.00.00.00.00.0-0.00.0-0.0-0.1-0.10.10.1-0.10.20.3
Conditioned locomotion0.70.81.90.60.50.2-0.70.60.60.60.80.70.9-0.90.90.91.0-0.91.11.1-1.01.21.4
Cocaine response after cond. corrected0.50.60.9-0.2-0.20.7-0.70.70.91.00.80.90.7-0.70.70.80.8-0.80.70.7-0.80.91.0
Cocaine response after cond. not corrected0.80.91.8-0.00.10.7-0.80.61.01.21.01.10.9-0.90.91.01.0-1.00.90.9-1.01.21.3
Cocaine response before conditioning1.41.72.8-0.4-0.40.9-1.00.81.21.41.41.31.6-1.61.61.31.2-1.41.41.4-1.41.51.7
Saline control response0.10.10.1-0.3-0.20.2-0.30.30.30.30.30.40.3-0.30.30.30.4-0.30.30.3-0.30.40.3
Bone: connectivity density0.30.50.70.40.6-0.60.7-0.7-0.5-0.4-0.6-0.6-0.80.8-0.8-0.8-0.80.7-0.8-0.80.8-0.8-0.8
Bone: cortical apparent density2.43.33.81.71.6-1.91.8-1.7-1.9-1.9-1.9-2.0-1.91.9-1.9-1.8-1.91.9-1.8-1.81.8-1.8-1.6
Bone: cortical area2.63.94.4-1.6-1.41.9-2.02.02.02.12.02.12.1-2.12.12.02.0-2.02.02.1-2.02.02.0
Bone: cortical porosity0.50.52.41.61.5-1.00.8-1.0-0.6-0.5-0.5-0.5-0.50.5-0.5-0.5-0.50.5-0.5-0.50.4-0.20.1
Bone: cortical porosity0.60.73.11.81.7-1.10.9-1.1-0.7-0.6-0.7-0.6-0.60.6-0.6-0.6-0.60.6-0.5-0.50.5-0.30.0
Bone: cortical thickness1.42.42.9-1.1-1.01.4-1.61.51.51.61.61.51.7-1.71.71.61.5-1.61.71.7-1.61.61.7
Bone: cortical thickness0.10.10.80.80.9-0.50.3-0.3-0.2-0.1-0.1-0.10.0-0.00.00.0-0.00.00.10.1-0.00.10.3
Bone: cortical tissue density2.73.74.31.81.7-2.01.9-1.9-2.0-2.0-2.0-2.1-2.02.0-2.0-1.9-2.02.0-1.9-1.91.9-1.9-1.7
Condit. Reinf. active minus inactive responses0.30.30.50.50.7-0.50.6-0.7-0.7-0.7-0.6-0.7-0.40.4-0.4-0.6-0.70.6-0.4-0.40.5-0.5-0.5
Condit. Reinf. active-inactive response ratio0.20.20.40.40.6-0.40.5-0.5-0.5-0.4-0.4-0.5-0.30.3-0.3-0.4-0.50.4-0.3-0.30.4-0.4-0.4
Condit. Reinf. active responses1.11.42.51.41.6-1.31.3-1.4-1.3-1.2-1.2-1.2-1.11.1-1.1-1.2-1.21.1-1.1-1.11.1-0.9-0.8
Condit. Reinf. inactive responses0.80.91.51.11.2-1.11.1-1.1-1.0-1.0-1.0-0.9-1.01.0-1.0-1.0-0.90.9-1.0-1.00.9-0.7-0.6
Incentive salience index mean0.00.10.40.40.6-0.20.3-0.4-0.2-0.2-0.2-0.2-0.10.1-0.1-0.2-0.20.1-0.1-0.10.1-0.00.0
Condit. Reinf. lever presses0.10.20.3-0.00.10.3-0.30.20.40.50.40.40.4-0.40.40.30.4-0.40.40.4-0.40.60.6
Condit. Reinf. active minus inactive responses3.84.95.6-1.9-1.92.1-2.32.32.22.22.22.12.3-2.32.32.22.2-2.22.42.3-2.32.32.2
Condit. Reinf. active-inactive response ratio2.52.94.4-0.9-0.81.3-1.71.51.51.71.71.61.8-1.81.81.81.8-1.81.91.9-1.82.12.1
Condit. Reinf. active responses4.56.37.2-2.3-2.32.4-2.72.62.52.42.52.42.6-2.62.62.42.4-2.52.62.6-2.52.52.3
Condit. Reinf. inactive responses1.31.73.2-1.8-1.81.5-1.41.41.31.21.31.21.3-1.31.31.11.1-1.21.21.2-1.10.90.7
Condit. Reinf. lever presses7.19.814.8-3.9-3.83.4-3.43.43.12.93.02.93.1-3.13.13.13.0-3.03.13.1-2.92.72.3
Condit. Reinf. lever reinforcers received5.57.78.6-2.5-2.52.7-2.92.92.72.72.82.72.9-2.92.92.82.7-2.82.92.9-2.82.82.6
Conditioned reinforcement - actives0.10.21.01.01.0-0.40.1-0.3-0.0-0.2-0.3-0.3-0.40.4-0.4-0.4-0.30.3-0.2-0.20.2-0.10.0
Conditioned reinforcement - inactives0.60.91.1-0.5-0.40.9-0.90.81.01.01.01.00.9-0.90.90.91.0-1.01.01.0-1.00.91.0
Conditioned locomotion1.92.56.52.52.4-1.91.5-1.8-1.4-1.3-1.5-1.5-1.51.5-1.5-1.5-1.51.4-1.2-1.31.4-1.0-0.9
Patch foraging indifference point 0 sec0.20.40.6-0.5-0.40.5-0.60.60.60.70.60.60.7-0.70.70.60.7-0.60.70.7-0.70.60.7
Patch foraging indifference point AUC0.40.51.30.70.6-0.60.8-0.8-0.6-0.6-0.6-0.5-0.80.8-0.8-0.5-0.60.7-1.1-1.10.7-0.5-0.5
Delay disc. indifference point, 0s delay0.40.41.7-1.3-1.31.0-0.70.70.80.90.60.50.5-0.50.50.40.4-0.40.30.3-0.30.1-0.1
Delay disc. indifference point, 16s delay1.51.64.4-2.1-2.11.6-1.41.41.31.31.31.11.1-1.11.10.90.9-1.01.31.2-0.90.60.4
Delay disc. indifference point, 2s delay0.30.31.7-1.3-1.30.4-0.20.3-0.0-0.2-0.2-0.3-0.20.2-0.2-0.3-0.30.3-0.3-0.30.4-0.8-1.1
Delay disc. indifference point, 24s delay1.31.43.2-1.8-1.81.5-1.21.21.31.31.31.21.1-1.11.11.11.1-1.11.01.0-1.00.80.7
Delay disc. indifference point, 4s delay0.10.10.4-0.6-0.60.4-0.40.30.20.20.20.10.1-0.10.10.10.1-0.10.20.1-0.1-0.1-0.2
Delay disc. indifference point, 8s delay0.91.02.50.00.1-0.60.9-0.8-0.9-1.0-1.0-1.0-1.01.0-1.0-1.1-1.11.1-1.0-1.01.2-1.4-1.6
Indifference point function ln k0.30.50.8-0.8-0.80.7-0.90.90.50.50.60.50.7-0.70.70.50.5-0.60.90.9-0.60.50.5
Indifference point function log k0.30.50.8-0.8-0.80.7-0.90.90.50.50.60.50.7-0.70.70.50.5-0.60.90.9-0.60.50.5
Patch foraging total patch changes 0 sec0.30.50.7-0.7-0.60.6-0.70.70.70.80.70.70.7-0.70.70.70.7-0.70.80.8-0.70.60.7
Patch foraging total patch changes 12 sec0.20.30.6-0.3-0.30.6-0.50.50.70.80.60.60.5-0.50.50.60.6-0.60.40.4-0.60.70.7
Patch foraging total patch changes 18 sec0.20.20.60.80.7-0.50.7-0.6-0.4-0.3-0.4-0.3-0.40.4-0.4-0.3-0.40.5-0.7-0.70.4-0.3-0.2
Patch foraging total patch changes 24 sec0.40.71.2-1.1-1.11.0-0.91.01.00.90.90.90.8-0.80.80.80.9-0.80.40.5-0.80.70.6
Patch foraging total patch changes 6 sec0.10.10.40.10.20.2-0.10.10.40.60.30.40.3-0.30.30.40.4-0.30.20.2-0.30.40.5
Patch foraging time to switch 0 sec0.81.61.91.11.2-1.11.4-1.4-1.1-1.0-1.2-1.1-1.31.3-1.3-1.3-1.21.3-1.4-1.31.3-1.3-1.3
Patch foraging water rate 0 sec0.30.71.21.01.1-1.10.8-0.8-0.9-0.9-0.9-0.9-0.70.7-0.7-0.7-0.80.8-0.8-0.80.7-0.6-0.5
Patch foraging water rate 12 sec0.61.21.8-1.1-1.21.1-1.11.20.90.81.00.91.2-1.21.21.21.0-1.11.31.3-1.11.00.9
Patch foraging water rate 18 sec0.50.81.60.10.3-0.70.6-0.6-1.0-1.0-1.0-1.1-0.80.8-0.8-0.9-1.01.0-0.8-0.81.0-1.0-1.3
Patch foraging water rate 24 sec0.30.41.1-0.2-0.40.5-0.70.70.30.30.50.40.7-0.70.70.80.5-0.61.11.0-0.70.60.7
Patch foraging water rate 6 sec0.10.10.5-0.7-0.70.4-0.40.50.1-0.10.20.10.3-0.30.30.20.1-0.20.30.3-0.1-0.0-0.1
Seeking ratio, delayed vs. immediate footshock1.21.52.8-1.6-1.71.2-1.11.30.91.11.11.31.3-1.31.31.21.3-1.21.11.1-1.21.00.9
Distance traveled before self-admin2.12.73.4-1.4-1.31.5-1.71.71.51.71.61.61.7-1.71.71.81.8-1.71.71.7-1.71.71.7
Distance traveled after self-admin2.73.34.5-1.7-1.61.9-2.01.82.02.11.91.81.7-1.71.72.02.0-1.81.71.6-1.81.81.8
Extensor digitorum longus weight0.20.91.00.91.0-1.00.9-1.0-0.9-0.9-0.9-1.0-1.01.0-1.0-0.9-0.91.0-0.9-0.91.0-0.9-0.9
Bone: elastic displacement0.00.00.1-0.1-0.1-0.00.1-0.1-0.1-0.2-0.1-0.1-0.20.2-0.2-0.1-0.10.2-0.3-0.30.2-0.1-0.2
Bone: elastic work2.63.44.1-1.6-1.51.9-1.91.81.91.91.91.81.9-1.91.92.02.0-1.91.81.8-1.91.91.8
Bone: endosteal estimation1.12.43.2-1.8-1.71.8-1.61.61.71.81.61.71.4-1.41.41.41.5-1.51.31.3-1.41.31.2
Bone: endosteal perimeter0.91.92.7-1.7-1.61.6-1.51.61.51.41.41.51.3-1.31.31.31.4-1.31.21.2-1.31.20.9
Epididymis fat weight0.00.00.20.40.10.0-0.1-0.00.20.20.20.2-0.00.0-0.00.20.1-0.10.00.0-0.20.30.4
Delta time in closed arm before/after self-admin0.10.10.4-0.6-0.60.4-0.30.20.40.30.10.1-0.20.2-0.2-0.1-0.10.1-0.2-0.20.2-0.2-0.4
Delta time in open arm before/after self-admin0.10.10.50.50.3-0.2-0.10.1-0.10.10.20.20.3-0.30.30.30.3-0.40.40.4-0.40.60.7
Diff in mean of infusions in LGA sessions0.00.00.1-0.4-0.00.10.2-0.1-0.0-0.00.10.00.2-0.20.20.2-0.1-0.1-0.10.0-0.0-0.0-0.1
Delay discount exponential model param0.20.31.81.31.3-0.70.4-0.5-0.3-0.2-0.2-0.1-0.20.2-0.2-0.0-0.00.1-0.2-0.20.00.30.6
Extinction: sum of active levers before priming2.42.63.4-1.4-1.51.6-1.51.61.61.81.61.71.7-1.71.71.71.6-1.61.51.6-1.61.71.6
Active lever presses in extinction session 60.40.41.0-1.0-0.80.9-0.80.60.91.00.60.60.4-0.40.40.50.5-0.40.20.3-0.40.40.2
Bone: final force1.82.83.4-1.5-1.41.7-1.71.71.71.81.71.71.8-1.81.81.71.7-1.71.71.7-1.71.51.6
Bone: final moment2.84.45.2-1.8-1.72.1-2.12.12.12.32.22.12.2-2.22.22.22.1-2.12.12.1-2.12.02.1
Food consumed during 24 hour testing period0.20.30.7-0.8-0.80.5-0.60.60.50.40.50.50.6-0.60.60.50.5-0.50.60.6-0.50.50.3
Glucose0.10.20.50.1-0.0-0.20.3-0.3-0.3-0.2-0.4-0.3-0.70.7-0.7-0.6-0.40.5-0.5-0.50.5-0.4-0.5
Heart weight1.01.62.5-0.3-0.41.0-1.00.91.31.31.41.41.5-1.51.51.41.4-1.41.21.2-1.41.51.6
Delay discount hyperbolic model param0.20.21.41.21.2-0.50.3-0.3-0.1-0.0-0.00.1-0.00.0-0.00.20.2-0.1-0.00.0-0.20.50.8
Intermittent access intake day 1-15 change0.30.61.3-1.1-1.00.9-0.91.01.00.90.80.80.5-0.50.50.50.6-0.60.60.6-0.60.60.4
Intermittent access intake escalation0.20.30.7-0.8-0.80.7-0.80.80.70.70.60.60.4-0.40.40.40.5-0.50.50.5-0.50.50.3
Intermittent access intake escalation 22.12.43.0-1.6-1.51.7-1.61.61.71.71.61.61.4-1.41.41.41.5-1.51.61.5-1.51.61.4
Intermitt. access day 1 inactive lever presses1.34.77.3-2.7-2.52.5-2.42.42.32.42.22.22.0-2.02.02.02.1-2.12.12.1-2.01.71.7
Intermitt. access day 15 inactive lever presses0.51.02.5-1.6-1.31.2-1.11.11.00.90.90.90.9-0.90.90.90.9-0.90.90.9-0.90.80.6
Intermitt. access escalation Index0.30.40.6-0.6-0.50.4-0.50.60.20.40.60.50.7-0.70.70.70.6-0.60.80.8-0.70.70.7
Intermittent access day 1 total infusions0.30.41.61.21.2-1.10.5-0.6-1.1-0.8-0.6-0.7-0.30.3-0.3-0.3-0.20.30.10.00.2-0.10.1
Intermittent access day 15 total infusions0.10.20.5-0.10.10.1-0.40.40.10.20.20.20.4-0.40.40.40.5-0.40.70.6-0.40.50.5
Intermittent access terminal intake (last 3 days)0.70.91.5-0.3-0.30.7-0.90.90.70.80.80.81.0-1.01.01.01.1-1.01.21.2-1.01.11.2
Intermittent access total infusions0.10.10.30.50.5-0.2-0.20.1-0.2-0.1-0.0-0.10.2-0.20.20.20.3-0.20.60.5-0.30.30.5
Intermittent access day 1 locomotion0.10.10.50.70.7-0.4-0.30.1-0.2-0.2-0.0-0.10.2-0.20.20.20.2-0.20.50.5-0.30.40.6
Intermittent access day 15 total locomotion0.00.10.50.70.7-0.40.0-0.2-0.20.0-0.2-0.2-0.20.2-0.2-0.2-0.10.10.20.10.00.20.2
Intermittent access total locomotion0.30.41.81.31.3-0.80.4-0.5-0.6-0.5-0.5-0.6-0.50.5-0.5-0.5-0.50.4-0.1-0.20.3-0.10.0
Intermittent access standard deviation1.73.55.4-2.3-2.22.1-2.02.11.91.61.81.71.8-1.81.81.81.9-1.81.91.9-1.81.51.4
Left kidney weight3.215.120.5-2.2-2.23.5-3.73.34.14.34.24.24.0-4.04.04.14.1-4.13.83.8-4.24.44.5
Right kidney weight3.214.717.6-2.8-2.73.6-3.73.54.04.24.14.13.9-3.93.93.94.0-4.03.83.8-4.04.14.1
Cocaine induced anxiety0.30.51.2-0.10.3-0.30.6-0.7-0.3-0.8-0.7-0.8-0.60.6-0.6-0.6-0.80.8-0.8-0.70.8-1.0-1.1
Post-drug Anxiety0.10.10.5-0.7-0.20.4-0.10.00.3-0.0-0.0-0.2-0.00.0-0.00.0-0.20.1-0.2-0.10.2-0.3-0.5
Baseline Anxiety1.31.62.8-0.5-0.50.9-1.11.10.81.51.31.41.3-1.31.31.31.4-1.41.31.3-1.41.51.7
Tail length5.320.824.2-4.5-4.54.9-4.74.74.94.84.84.84.5-4.54.54.44.5-4.54.34.3-4.54.24.0
Length with tail6.829.833.3-5.4-5.35.8-5.65.65.75.75.65.75.6-5.65.65.45.4-5.55.35.3-5.45.04.8
Length without tail1.85.77.7-2.8-2.72.6-2.42.42.52.42.42.42.4-2.42.42.32.3-2.32.32.3-2.32.01.8
Times rat made contact with spout0.50.61.81.31.2-1.10.9-1.0-0.8-0.8-0.7-0.7-0.60.6-0.6-0.7-0.70.6-0.6-0.60.6-0.4-0.3
Lifetime Intake0.10.10.60.80.8-0.50.1-0.1-0.5-0.3-0.3-0.3-0.10.1-0.1-0.10.00.00.30.3-0.00.10.3
Liver weight, left0.20.31.00.20.10.3-0.40.20.60.70.70.70.5-0.50.50.50.5-0.60.50.5-0.60.71.0
Liver weight, right0.00.10.1-0.1-0.20.2-0.20.20.30.20.20.30.2-0.20.20.20.3-0.20.30.2-0.20.30.3
Locomotor activity0.50.72.11.31.4-1.01.1-1.1-0.6-0.4-0.7-0.5-0.80.8-0.8-0.7-0.60.7-1.0-1.00.7-0.6-0.4
Locomotor testing distance1.11.92.71.61.6-1.51.5-1.5-1.3-1.2-1.3-1.2-1.41.4-1.4-1.3-1.41.4-1.5-1.51.3-1.3-1.1
Locomotor testing rearing1.22.44.92.12.2-1.81.7-1.8-1.5-1.4-1.4-1.4-1.41.4-1.4-1.3-1.51.4-1.6-1.61.4-1.1-1.0
Locomotion in novel chamber0.50.71.00.50.3-0.70.7-0.6-0.8-0.7-0.9-0.8-1.01.0-1.0-1.0-0.80.9-0.8-0.80.9-0.9-1.0
Locomotion in novel chamber post-restriction0.10.21.2-1.0-1.10.20.00.3-0.2-0.5-0.1-0.0-0.00.0-0.0-0.0-0.00.1-0.1-0.10.1-0.3-0.5
Fecal boli incidents, locomotor time 12.74.05.21.21.3-1.91.7-1.7-1.9-2.0-2.1-2.1-2.32.3-2.3-2.1-2.12.1-2.1-2.12.1-2.1-2.2
Change in fecal boli incidents, locomotor task0.00.00.10.30.2-0.10.1-0.1-0.1-0.30.0-0.00.2-0.20.20.2-0.1-0.10.20.1-0.10.20.2
Time >=10cm from walls, locomotor time 10.00.00.1-0.1-0.0-0.00.0-0.0-0.0-0.00.0-0.0-0.20.2-0.2-0.1-0.10.1-0.3-0.20.1-0.1-0.1
Bouts of movement, locomotor time 10.50.63.7-1.9-1.71.1-0.91.10.70.40.60.50.4-0.40.40.40.4-0.40.20.3-0.30.1-0.3
Total resting periods, locomotor time 10.50.53.6-1.9-1.70.9-0.81.00.50.10.40.30.2-0.20.20.20.3-0.20.10.1-0.2-0.1-0.5
Rest time, locomotor task time 10.10.10.3-0.10.1-0.30.1-0.0-0.4-0.6-0.3-0.4-0.40.4-0.4-0.4-0.30.3-0.4-0.40.3-0.2-0.3
Distance moved, locomotor task time 10.20.30.80.70.50.2-0.1-0.10.50.80.50.60.5-0.50.50.50.5-0.50.60.6-0.50.60.9
Vertical activity count, locomotor time 10.61.52.1-0.5-0.61.0-1.00.91.31.41.31.41.3-1.31.31.21.3-1.31.41.3-1.31.41.5
Time >=10cm from walls, locomotor time 20.00.00.20.00.00.2-0.00.00.20.20.30.30.2-0.20.20.40.1-0.20.00.1-0.30.20.4
Bouts of movement, locomotor time 20.30.51.6-0.5-0.3-0.00.2-0.3-0.3-0.3-0.5-0.6-0.60.6-0.6-0.7-0.90.7-1.0-0.90.8-1.0-1.3
Total resting periods, locomotor time 20.30.51.5-0.3-0.1-0.20.3-0.4-0.4-0.3-0.5-0.7-0.60.6-0.6-0.7-1.00.8-1.0-0.90.8-1.1-1.2
Rest time, locomotor task time 20.30.40.6-0.6-0.40.3-0.60.60.40.20.60.50.7-0.70.70.60.6-0.70.70.7-0.70.70.8
Distance moved, locomotor task time 20.10.10.70.80.7-0.20.4-0.5-0.00.3-0.00.0-0.20.2-0.2-0.0-0.10.1-0.2-0.20.1-0.00.1
Vertical activity count, locomotor time 20.10.10.3-0.5-0.50.5-0.40.30.60.50.40.50.2-0.20.20.40.4-0.30.20.2-0.30.30.2
Light reinforcement 10.10.30.40.50.5-0.50.6-0.6-0.5-0.4-0.6-0.5-0.60.6-0.6-0.4-0.50.6-0.6-0.60.6-0.5-0.5
Light reinforcement 26.19.411.42.42.4-3.03.1-3.0-3.1-3.2-3.2-3.2-3.23.2-3.2-3.1-3.13.2-2.9-3.03.2-3.4-3.2
Bone: marrow area1.22.53.3-1.8-1.71.8-1.71.71.81.81.71.81.5-1.51.51.51.5-1.51.31.4-1.51.41.2
Bone: maximum diameter1.62.93.8-1.4-1.31.7-1.81.71.91.91.81.81.7-1.71.71.61.7-1.71.71.7-1.71.61.6
Bone: maximum force3.46.06.8-2.4-2.32.5-2.62.62.52.62.52.42.5-2.52.52.42.5-2.42.42.5-2.42.32.3
Bone: maximum moment4.57.99.0-2.6-2.52.9-3.02.92.93.02.92.82.8-2.82.82.82.8-2.82.82.8-2.82.72.6
Mean time between licks in bursts0.10.20.4-0.4-0.20.3-0.40.30.30.40.50.30.6-0.60.60.40.4-0.50.70.6-0.50.40.5
Mean num. licks in bursts0.61.01.6-0.7-0.71.0-0.90.81.21.31.11.21.0-1.01.00.90.9-1.00.90.9-1.01.11.0
Cd content in liver0.60.70.90.60.7-0.90.9-0.8-0.9-1.0-0.8-0.9-0.80.8-0.8-0.9-0.90.8-0.8-0.80.8-0.9-0.8
Co content in liver1.01.21.91.21.4-1.31.1-1.1-1.1-1.2-1.1-1.1-1.11.1-1.1-1.1-1.11.1-1.0-1.01.0-1.1-0.9
Cu content in liver1.21.41.7-1.2-1.11.2-1.21.21.21.21.21.21.3-1.31.31.21.2-1.21.21.2-1.21.11.1
Fe content in liver0.91.11.50.60.6-0.81.0-0.9-0.9-0.9-1.0-1.0-1.21.2-1.2-1.1-1.11.1-1.2-1.21.1-1.1-1.2
K content in liver0.80.81.0-0.6-0.50.8-0.80.70.91.00.90.90.9-0.90.90.90.9-0.90.90.9-0.91.01.0
Mg content in liver0.10.10.40.20.30.1-0.20.10.30.30.40.30.5-0.50.50.30.3-0.40.40.4-0.40.50.6
Mn content in liver0.91.03.00.50.50.3-0.70.50.81.11.01.01.0-1.01.01.01.0-1.11.01.0-1.11.41.7
Na content in liver3.23.44.3-1.3-1.41.8-1.81.72.02.11.92.01.8-1.81.81.91.9-1.91.81.8-1.92.02.0
Rb content in liver0.00.00.10.20.20.10.1-0.10.10.20.10.10.2-0.20.20.10.1-0.1-0.00.0-0.10.10.1
Se content in liver2.83.36.42.52.4-2.21.9-2.0-1.8-1.7-1.8-1.7-1.81.8-1.8-1.7-1.61.7-1.7-1.71.6-1.3-1.1
Sr content in liver0.40.30.50.60.6-0.70.7-0.7-0.6-0.6-0.6-0.6-0.60.6-0.6-0.6-0.60.5-0.4-0.40.5-0.6-0.4
Zn content in liver2.32.54.52.02.1-1.91.9-2.0-1.6-1.5-1.5-1.5-1.41.4-1.4-1.5-1.51.5-1.5-1.41.4-1.2-1.0
Bone: minimum diameter6.010.911.7-3.0-2.93.3-3.33.33.43.43.43.43.4-3.43.43.43.3-3.43.33.3-3.33.33.1
Time in familiar zone, hab. session 10.30.20.4-0.6-0.50.6-0.50.50.60.70.50.60.4-0.40.40.40.4-0.50.50.5-0.50.40.4
Time in novel zone, hab. session 10.10.10.40.70.6-0.50.4-0.4-0.4-0.3-0.3-0.3-0.20.2-0.2-0.3-0.20.3-0.3-0.30.3-0.2-0.1
Total zone transitions, hab. session 10.50.71.0-0.8-0.80.8-0.80.80.80.80.80.90.7-0.70.71.00.9-0.80.80.8-0.80.91.0
Total locomotion distance, hab. session 12.94.16.2-2.4-2.52.2-2.12.12.01.92.02.01.9-1.91.92.02.0-2.01.91.9-1.91.81.7
Locomotion velocity, hab. session 11.21.73.5-1.8-1.91.5-1.41.41.31.11.31.21.3-1.31.31.31.3-1.21.21.2-1.21.11.0
Time in familiar zone, hab. session 20.50.52.0-1.3-1.40.9-0.80.90.70.60.60.50.5-0.50.50.50.5-0.50.60.6-0.40.20.0
Time in novel zone, hab. session 20.50.51.21.01.1-0.80.8-0.8-0.8-0.7-0.7-0.7-0.60.6-0.6-0.6-0.60.7-0.8-0.80.6-0.5-0.4
Total zone transitions, hab. session 20.20.21.11.11.0-0.70.4-0.6-0.4-0.3-0.2-0.2-0.10.1-0.1-0.1-0.20.10.0-0.00.00.20.5
Total locomotion distance, hab. session 20.40.50.7-0.4-0.50.5-0.60.50.50.50.70.60.8-0.80.80.70.6-0.70.80.8-0.70.80.8
Locomotion velocity, hab. session 20.30.40.8-0.1-0.20.3-0.50.40.40.50.60.50.8-0.80.80.70.6-0.70.80.8-0.70.80.9
Novel to familiar place preference ratio1.21.32.0-0.9-1.01.1-1.11.11.11.11.11.21.1-1.11.11.41.4-1.20.90.9-1.21.11.2
Novelty place preference1.01.11.8-0.8-0.91.1-1.01.01.11.01.01.21.0-1.01.01.31.3-1.10.80.8-1.11.11.1
Time in novel zone, NPP test0.60.71.2-0.5-0.60.8-0.80.80.80.80.80.90.8-0.80.81.11.1-0.90.60.6-0.90.80.9
Total zone transitions, NPP test0.10.20.30.10.1-0.40.3-0.3-0.4-0.5-0.5-0.5-0.60.6-0.6-0.5-0.50.5-0.4-0.50.5-0.4-0.5
Total locomotion distance, NPP test1.62.24.1-2.0-2.01.7-1.61.71.51.41.41.41.4-1.41.41.41.4-1.41.41.4-1.41.21.0
Locomotion velocity, NPP test2.13.04.8-2.2-2.21.9-1.91.91.71.61.71.61.7-1.71.71.71.6-1.61.61.6-1.61.51.3
Intraocular pressure0.10.10.3-0.5-0.2-0.10.1-0.0-0.3-0.3-0.3-0.3-0.50.5-0.5-0.4-0.50.4-0.4-0.40.4-0.5-0.6
Delta distance traveled before/after self-admin0.10.10.3-0.3-0.20.2-0.0-0.00.20.1-0.1-0.1-0.40.4-0.4-0.3-0.20.3-0.5-0.50.3-0.4-0.6
Delta ambulatory time before/after self-admin0.10.10.2-0.3-0.20.4-0.30.20.40.40.30.30.2-0.20.20.20.2-0.20.10.1-0.20.20.1
Parametrial fat weight0.20.41.31.11.2-0.80.7-0.7-0.6-0.5-0.5-0.4-0.50.5-0.5-0.3-0.40.5-0.5-0.50.4-0.3-0.1
Pavlov. Cond. lever latency0.40.51.1-0.2-0.1-0.40.5-0.4-0.7-0.7-0.7-0.7-0.70.7-0.7-0.6-0.70.7-0.7-0.70.7-1.0-1.0
Pavlov. Cond. magazine entry latency0.20.30.50.60.5-0.40.4-0.4-0.6-0.5-0.6-0.7-0.50.5-0.5-0.6-0.60.6-0.4-0.40.6-0.4-0.5
Pavlov. Cond. change in total contacts0.00.00.00.10.10.0-0.0-0.00.00.10.00.00.0-0.00.0-0.10.0-0.00.00.0-0.00.10.1
Pavlov. Cond. index score0.00.10.30.60.5-0.1-0.0-0.10.10.20.10.10.1-0.10.10.00.1-0.10.20.2-0.20.40.4
Pavlov. Cond. latency score0.10.10.30.40.40.1-0.20.10.30.40.30.30.3-0.30.30.20.3-0.30.30.3-0.30.50.5
Pavlov. Cond. lever contacts0.81.01.5-0.4-0.50.8-1.00.91.01.11.01.01.0-1.01.00.91.0-1.01.11.0-1.01.21.2
Pavlov. Cond. magazine entry number0.00.10.1-0.4-0.30.2-0.10.20.30.20.20.40.2-0.20.20.30.3-0.30.10.1-0.30.10.2
Pavlov. Cond. intertrial magazine entries0.20.20.90.80.9-0.70.6-0.6-0.4-0.3-0.4-0.3-0.30.3-0.3-0.2-0.30.3-0.3-0.30.3-0.2-0.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.60.5-0.0-0.1-0.00.10.30.20.20.2-0.20.20.10.2-0.20.30.3-0.30.50.6
Pavlov. Cond. response bias0.00.00.20.20.10.1-0.20.20.10.20.20.10.2-0.20.20.10.2-0.10.20.2-0.20.40.3
Pavlov. Cond. lever latency3.85.27.52.72.7-2.52.5-2.5-2.2-2.2-2.2-2.1-2.22.2-2.2-2.3-2.12.2-2.3-2.22.1-2.0-1.7
Pavlov. Cond. magazine entry latency2.22.64.7-2.2-2.21.9-1.81.81.61.61.61.41.5-1.51.51.51.4-1.51.61.6-1.51.21.0
Pavlov. Cond. change in total contacts5.48.713.0-3.6-3.53.3-3.23.22.92.72.82.72.9-2.92.93.02.8-2.82.92.9-2.82.52.2
Pavlov. Cond. index score3.64.98.4-2.9-2.92.6-2.52.52.22.12.12.02.1-2.12.12.22.0-2.02.12.1-2.01.81.5
Pavlov. Cond. latency score3.24.27.5-2.7-2.72.4-2.32.32.12.02.01.81.9-1.91.92.01.8-1.92.02.0-1.91.61.3
Pavlov. Cond. lever contacts4.25.88.8-3.0-2.92.7-2.62.62.42.32.32.32.3-2.32.32.42.3-2.32.42.3-2.22.11.8
Pavlov. Cond. magazine entry number1.51.95.02.22.2-1.81.6-1.7-1.4-1.3-1.2-1.1-1.21.2-1.2-1.2-1.11.2-1.2-1.21.1-0.8-0.5
Pavlov. Cond. intertrial magazine entries0.91.42.51.61.5-1.51.4-1.4-1.2-1.3-1.2-1.0-1.01.0-1.0-1.1-1.11.1-1.2-1.11.0-0.9-0.7
Pavlov. Cond. lever-magazine prob. diff.3.85.18.2-2.9-2.82.6-2.52.52.32.32.22.12.1-2.12.12.22.1-2.12.22.2-2.11.91.6
Pavlov. Cond. response bias5.06.89.5-3.1-3.12.9-2.82.92.62.52.52.42.5-2.52.52.62.4-2.52.62.6-2.42.31.9
Time in closed arm before self-admin0.10.10.70.40.9-0.60.6-0.4-0.7-0.6-0.3-0.40.1-0.10.10.0-0.20.10.30.20.1-0.3-0.0
Time in closed arm after self-admin0.20.21.3-1.1-0.60.2-0.10.3-0.1-0.1-0.1-0.3-0.00.0-0.0-0.1-0.30.20.10.00.2-0.7-0.8
Time in open arm before self-admin1.01.11.7-1.1-1.31.2-1.21.11.31.21.11.11.0-1.01.01.01.1-1.00.70.8-1.01.00.8
Time in open arm after self-admin1.82.04.2-0.1-0.51.0-1.21.11.31.41.51.61.5-1.51.51.41.6-1.61.21.3-1.62.02.0
Bone: periosteal estimation2.45.16.3-2.2-2.02.4-2.32.32.42.52.42.52.3-2.32.32.22.3-2.32.12.1-2.22.22.0
Bone: periosteal perimeter2.13.54.1-1.8-1.82.0-2.02.02.01.91.91.91.9-1.91.91.91.9-1.91.81.8-1.81.71.6
Bone: post-yield work1.11.63.4-1.9-1.81.5-1.51.61.31.21.21.11.1-1.11.11.21.2-1.11.11.1-1.11.00.7
Progressive ratio test 1 active lever presses0.40.51.30.30.4-0.1-0.60.6-0.00.40.40.50.7-0.70.70.70.9-0.81.11.0-0.81.01.1
Progressive ratio test 1 breakpoint0.60.71.70.10.20.2-0.70.70.20.60.60.70.9-0.90.90.91.0-0.91.31.2-1.01.11.3
Progressive ratio test 1 inactive lever presses0.60.81.3-0.9-0.80.8-1.01.00.80.80.80.80.8-0.80.80.81.0-0.91.11.1-0.90.80.9
Progressive ratio test 2 active lever presses0.10.10.40.50.6-0.60.2-0.2-0.6-0.4-0.4-0.5-0.30.3-0.3-0.3-0.10.2-0.0-0.10.2-0.1-0.1
Progressive ratio test 2 breakpoint0.10.10.50.50.7-0.60.2-0.2-0.6-0.4-0.4-0.5-0.30.3-0.3-0.3-0.10.3-0.0-0.10.2-0.1-0.1
Progressive ratio test 2 inactive lever presses0.50.71.7-1.3-1.21.0-1.11.10.70.60.70.60.8-0.80.80.80.8-0.80.90.9-0.70.60.4
Incentive Sensitization - Responses0.40.50.60.40.5-0.60.7-0.7-0.7-0.8-0.8-0.8-0.70.7-0.7-0.7-0.70.8-0.8-0.80.8-0.8-0.8
Incentive Sensitization - Breakpoint0.40.60.70.40.5-0.70.8-0.7-0.8-0.8-0.8-0.8-0.80.8-0.8-0.8-0.70.8-0.8-0.80.8-0.8-0.9
Sum of active levers in priming session hrs 5-60.10.10.60.60.8-0.30.3-0.4-0.20.0-0.0-0.10.2-0.20.20.1-0.30.0-0.1-0.00.00.10.2
Progressive ratio0.60.92.1-0.1-0.1-0.40.6-0.7-0.2-0.9-0.9-0.9-1.21.2-1.2-1.2-1.11.1-1.1-1.11.1-1.3-1.5
Food seeking constrained by brief footshock2.53.05.5-2.1-2.41.9-1.92.01.81.51.61.51.7-1.71.71.71.5-1.61.81.7-1.61.51.3
Seeking ratio, punishment vs. effort1.31.92.6-1.1-1.01.1-1.21.40.71.11.31.21.6-1.61.61.61.4-1.51.61.5-1.51.41.5
Retroperitoneal fat weight0.41.72.51.51.6-1.51.5-1.4-1.3-1.2-1.2-1.2-1.31.3-1.3-1.2-1.11.3-1.4-1.41.2-1.2-0.9
Reaction time number correct0.10.10.91.00.8-0.1-0.1-0.00.00.00.20.10.2-0.20.20.30.2-0.20.30.3-0.30.50.6
Reaction time mean minus median0.10.20.3-0.2-0.10.4-0.30.30.40.40.40.40.6-0.60.60.40.4-0.50.60.5-0.50.40.5
Reaction time mean minus median AUC0.10.40.7-0.3-0.20.6-0.50.50.50.60.60.50.8-0.80.80.60.6-0.60.60.6-0.70.60.7
Reaction time num false alarms1.01.42.51.41.6-1.51.2-1.3-1.1-1.0-1.1-1.1-1.21.2-1.2-1.2-1.31.1-1.1-1.11.1-0.9-0.9
Reaction time num false alarms AUC1.32.13.31.71.8-1.71.4-1.6-1.4-1.2-1.4-1.4-1.51.5-1.5-1.5-1.51.4-1.3-1.31.3-1.2-1.0
Reaction time trials correct on left0.10.10.91.00.8-0.1-0.1-0.00.00.00.20.10.2-0.20.20.30.2-0.20.30.3-0.30.50.6
Reaction time trials on left0.10.11.01.00.8-0.1-0.0-0.00.00.00.20.10.2-0.20.20.30.2-0.20.30.3-0.30.50.6
Reaction time mean0.10.10.20.20.4-0.30.3-0.3-0.4-0.3-0.3-0.4-0.20.2-0.2-0.4-0.30.3-0.2-0.20.3-0.3-0.2
Reaction time mean AUC0.10.20.50.50.7-0.60.5-0.5-0.5-0.4-0.5-0.5-0.40.4-0.4-0.6-0.50.4-0.4-0.40.4-0.4-0.3
Median of all reaction times0.30.40.60.50.6-0.70.6-0.6-0.7-0.6-0.7-0.7-0.70.7-0.7-0.8-0.70.7-0.6-0.60.6-0.6-0.6
Reaction time omissions0.30.51.91.11.4-0.80.8-0.8-0.6-0.6-0.6-0.5-0.60.6-0.6-0.5-0.40.5-0.6-0.60.5-0.4-0.3
Reaction time false alarm rate1.11.62.10.81.0-1.41.2-1.3-1.2-1.0-1.3-1.2-1.41.4-1.4-1.5-1.41.3-1.2-1.21.3-1.3-1.3
Reaction time premature initiation rate0.00.00.1-0.2-0.10.0-0.00.0-0.1-0.2-0.1-0.20.0-0.00.0-0.0-0.20.10.10.10.1-0.2-0.3
Reaction time premature initiations0.00.00.20.40.4-0.10.0-0.1-0.1-0.2-0.0-0.10.1-0.10.10.1-0.1-0.00.20.2-0.00.10.0
Std. dev. reaction times0.10.10.2-0.20.10.2-0.10.10.20.20.30.20.5-0.50.50.30.2-0.30.40.4-0.40.30.4
Reaction time trials completed0.10.11.01.00.8-0.1-0.0-0.00.00.00.20.10.2-0.20.20.30.2-0.20.30.3-0.30.50.6
Reaction time trials AUC0.10.21.61.21.0-0.30.1-0.2-0.1-0.10.0-0.00.1-0.10.10.10.1-0.10.20.2-0.20.40.6
Run reversals in cocaine runway, females0.10.10.20.1-0.2-0.10.1-0.1-0.1-0.2-0.2-0.2-0.40.4-0.4-0.3-0.30.3-0.4-0.40.4-0.5-0.5
Run reversals in cocaine runway, males1.31.32.81.41.4-1.51.5-1.3-1.7-1.3-1.2-1.0-0.90.9-0.9-0.9-0.90.9-0.8-0.90.9-0.8-0.6
Latency to leave start box in cocaine runway0.00.00.10.20.20.00.1-0.30.0-0.1-0.0-0.0-0.30.3-0.3-0.1-0.30.2-0.2-0.20.2-0.2-0.1
Latency to leave start box in cocaine runway, F0.30.31.00.81.0-0.50.7-0.8-0.6-0.5-0.5-0.5-0.50.5-0.5-0.4-0.60.5-0.5-0.50.5-0.5-0.4
Latency to leave start box in cocaine runway, M0.10.10.7-0.6-0.80.5-0.50.40.60.30.40.4-0.10.1-0.10.20.2-0.20.20.2-0.20.10.1
Std. dev. time between licks in bursts0.50.71.3-1.1-1.10.9-1.01.00.80.70.80.70.7-0.70.70.70.7-0.70.90.9-0.70.40.5
Total sessions with >9 infusions0.60.83.61.91.8-1.40.8-0.8-1.3-0.7-0.8-0.8-0.50.5-0.5-0.5-0.50.5-0.1-0.20.4-0.10.2
Short access day 1 total inactive lever presses0.70.92.1-1.4-1.41.3-1.11.11.00.90.80.70.8-0.80.80.80.7-0.81.00.9-0.70.40.4
Short access day 10 total inactive lever presses1.33.17.3-2.6-2.72.4-2.12.02.21.71.71.61.5-1.51.51.51.5-1.51.51.5-1.40.90.8
Short access day 1 total infusions0.60.71.4-0.1-0.20.2-0.70.80.30.70.70.71.0-1.01.01.01.0-0.91.11.1-1.01.21.2
Short access day 10 total infusions0.10.21.01.00.8-0.70.3-0.3-0.6-0.5-0.4-0.4-0.10.1-0.1-0.1-0.00.10.20.10.1-0.00.3
Short access total infusions0.20.21.11.11.0-0.80.3-0.3-0.7-0.5-0.5-0.5-0.20.2-0.2-0.2-0.20.20.20.10.10.00.3
Short access day 1 locomotion1.21.55.12.32.1-1.51.2-1.4-1.0-1.1-1.1-1.1-1.11.1-1.1-1.1-1.01.0-1.1-1.11.0-0.7-0.4
Short access day 10 total locomotion0.51.01.6-0.5-0.70.9-1.31.11.21.11.00.90.9-0.90.90.90.9-1.01.11.1-1.01.01.2
Short access total locomotion0.20.21.91.41.2-0.6-0.0-0.3-0.2-0.2-0.2-0.3-0.10.1-0.1-0.1-0.20.00.20.2-0.00.40.6
One hour access (0.3 mA shock)0.50.61.1-1.1-1.00.8-1.00.90.80.70.60.50.6-0.60.60.60.6-0.61.00.9-0.60.50.4
Compulsive drug intake2.63.04.4-1.9-2.11.9-1.81.81.81.61.71.81.7-1.71.71.71.7-1.71.71.7-1.71.61.6
One hour access (shock baseline)0.00.10.20.30.4-0.30.1-0.1-0.3-0.3-0.4-0.4-0.30.3-0.3-0.3-0.20.30.0-0.00.2-0.1-0.3
Social response proportion3.94.45.9-1.5-1.11.8-1.81.82.01.92.12.12.3-2.32.32.32.4-2.32.42.4-2.32.12.2
Social responses0.10.10.2-0.4-0.00.3-0.10.20.40.30.30.40.2-0.20.20.40.4-0.30.20.2-0.30.10.2
Social time0.40.62.6-1.6-1.41.1-0.80.90.70.50.70.70.6-0.60.60.60.7-0.60.40.4-0.60.30.1
Soleus weight0.72.13.20.60.7-1.31.3-1.2-1.5-1.7-1.5-1.6-1.51.5-1.5-1.5-1.41.5-1.6-1.61.6-1.7-1.8
Bone: stiffness1.62.63.1-1.6-1.61.7-1.71.81.61.71.61.61.6-1.61.61.51.5-1.61.71.7-1.61.41.4
Tibialis anterior weight0.00.00.10.20.3-0.30.1-0.2-0.1-0.1-0.1-0.1-0.20.2-0.2-0.1-0.10.1-0.2-0.20.10.10.1
Time to tail flick, vehicle, before self-admin0.20.21.51.21.0-0.20.1-0.30.20.50.20.30.2-0.20.20.20.2-0.20.20.2-0.30.60.8
Time to tail flick, vehicle, after self-admin0.40.51.9-1.4-1.30.8-0.90.90.60.30.60.50.5-0.50.50.70.6-0.60.50.5-0.50.30.1
Time to tail flick, test, before self-admin0.20.30.90.90.9-0.50.6-0.7-0.2-0.1-0.3-0.3-0.40.4-0.4-0.5-0.50.5-0.5-0.50.4-0.3-0.3
Time to tail flick, test, after self-admin0.10.10.40.40.6-0.30.2-0.3-0.1-0.2-0.2-0.3-0.20.2-0.2-0.3-0.40.3-0.2-0.20.3-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.40.41.4-1.2-1.10.6-0.70.80.50.20.50.40.5-0.50.50.60.5-0.50.50.5-0.50.30.2
Delta time to tail flick, test, before/after SA0.00.00.0-0.00.1-0.1-0.10.10.0-0.20.00.00.1-0.10.10.10.2-0.10.20.2-0.10.20.1
Tibia length2.05.66.1-2.0-1.92.3-2.32.32.42.42.52.52.5-2.52.52.42.4-2.42.42.4-2.42.52.4
Ambulatory time before self-admin1.42.02.4-1.5-1.31.4-1.51.51.31.41.41.41.4-1.41.41.61.5-1.51.41.4-1.41.41.3
Ambulatory time after self-admin2.83.34.0-2.0-1.82.0-2.01.91.92.01.81.81.7-1.71.71.91.8-1.81.71.7-1.81.61.5
Bone: tissue strength4.95.05.8-2.2-2.22.3-2.42.42.32.42.32.22.2-2.22.22.22.2-2.22.22.2-2.22.12.0
Total heroin consumption1.01.11.4-1.0-0.70.9-1.11.00.91.01.01.01.2-1.21.21.21.0-1.11.11.1-1.11.21.1
Bone: trabecular number0.10.20.3-0.5-0.30.4-0.40.30.50.60.40.50.4-0.40.40.40.4-0.40.30.3-0.40.30.3
Bone: trabecular spacing1.72.22.6-1.3-1.51.6-1.61.61.51.41.51.41.5-1.51.51.51.5-1.51.61.6-1.51.51.4
Bone: trabecular thickness0.10.20.70.70.8-0.60.5-0.5-0.3-0.3-0.3-0.2-0.30.3-0.3-0.4-0.30.3-0.4-0.30.2-0.2-0.0
Bone: trabecular tissue density2.33.43.91.61.7-1.71.9-1.8-1.8-1.8-1.8-1.7-1.91.9-1.9-1.9-1.81.9-2.0-2.01.9-2.0-1.7
Water consumed over 24 hours0.70.91.8-0.0-0.10.5-0.80.70.90.91.01.01.1-1.11.11.01.0-1.11.11.0-1.11.21.3
Number of responses in last shaping day0.40.40.7-0.4-0.20.3-0.40.50.30.50.70.70.8-0.80.80.80.8-0.80.80.8-0.80.70.7