Hub : Genes

Fam53a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Fam53a 0.03 0.02 3.7e-03 0.02 0.01 0.02 0.02 1.9e-03 8.5e-03 1.3e-03 2.2e-03
2 PL intron excision ratio chr14_81316162_81330648 0.07 0.04 1.8e-07 0.05 0.07 0.07 0.06 2.6e-06 5.3e-08 4.2e-08 1.9e-07
3 Liver isoform ratio NM_001107228.2 0.11 0.06 2.6e-13 0.08 0.11 0.1 0.11 2.6e-09 5.2e-12 9.5e-12 7.6e-12
4 PL mRNA stability Fam53a 0.03 0.02 9.8e-06 0.05 0.05 0.03 0.05 2.6e-06 8.9e-06 1.1e-04 4.3e-06
5 Liver intron excision ratio chr14_81316162_81330648 0.04 0.02 1.6e-05 0.03 0.05 0.04 0.04 1.5e-04 6.7e-06 3.7e-05 4.0e-05
6 NAcc intron excision ratio chr14_81316162_81330648 0.04 0.03 2.1e-08 0.07 0.05 0.06 0.06 1.6e-10 1.2e-07 5.8e-10 5.3e-09
7 NAcc mRNA stability Fam53a 0.03 0.02 3.0e-06 0.03 0.04 0.04 0.04 8.3e-06 3.0e-06 1.7e-06 1.1e-06
8 NAcc intron excision ratio chr14_81316162_81318592 0.05 0.03 4.6e-10 0.07 0.06 0.05 0.06 1.9e-10 1.9e-09 2.5e-08 5.1e-10
9 Liver mRNA stability Fam53a 0.08 0.04 5.7e-12 0.1 0.1 0.11 0.1 2.3e-11 2.1e-11 8.1e-12 1.2e-11
10 Eye intron excision ratio chr14_81315649_81330648 0.45 0.2 3.0e-03 0.03 0.06 0.01 0.05 1.2e-01 4.3e-02 2.5e-01 7.0e-02
11 Liver alternative TSS XM_063273161.1 0.04 0.03 9.3e-03 0.01 0.01 0.01 0.01 8.0e-03 1.1e-02 9.8e-03 1.5e-02
12 Adipose alternative TSS XM_063273161.1 0.04 0.03 2.7e-03 0.01 0.02 0.01 0 5.4e-02 5.0e-03 3.7e-02 8.8e-02
13 Adipose alternative TSS NM_001107228.2 0.04 0.03 2.2e-03 0.01 0.02 0 0 5.0e-02 4.8e-03 1.1e-01 7.2e-02
14 Adipose alternative TSS XM_063273161.1 0.03 0.02 9.0e-03 0 0.01 -0 0 1.7e-01 2.0e-02 3.9e-01 1.9e-01
15 Adipose alternative TSS NM_001107228.2 0.03 0.02 8.3e-03 0 0.01 -0 0 2.7e-01 2.4e-02 4.2e-01 2.5e-01
16 Liver intron excision ratio chr14_81335815_81348407 0.03 0.02 3.1e-03 0.03 0.01 0.01 0.02 7.9e-04 7.2e-03 7.6e-03 4.9e-03
17 NAcc isoform ratio NM_001107228.2 0.02 0.01 1.1e-03 0 0.02 0.01 0.01 4.3e-02 8.1e-04 1.6e-02 4.9e-03
18 NAcc intron excision ratio chr14_81335815_81338425 0.04 0.03 5.6e-04 0.01 0.02 0.01 0.01 2.9e-02 4.2e-04 2.4e-03 5.1e-03
19 Liver intron excision ratio chr14_81316162_81318592 0.03 0.02 4.6e-04 0.01 0.03 0.03 0.01 8.7e-03 3.5e-04 1.1e-04 1.2e-02
20 NAcc intron excision ratio chr14_81339188_81348407 0.03 0.02 6.4e-03 0.01 0.01 0.01 0.01 1.6e-02 6.4e-03 6.5e-03 5.0e-03
21 PL intron excision ratio chr14_81318926_81330648 0.03 0.02 2.0e-03 0.01 0.03 0.03 0.02 2.1e-02 8.4e-04 5.1e-04 3.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.81.43.1-1.8-1.3-1.3-1.4-1.3-1.4-1.31.1-1.1-1.10.9-1.31.3-1.31.3-0.9-1.00.60.9-0.4-0.0
Area under the delay curve1.51.85.70.20.1-0.00.6-0.00.40.6-0.60.9-0.6-2.32.4-2.42.3-2.2-0.7-0.80.71.0-1.52.0
BMI with tail2.06.913.12.61.72.43.12.73.23.2-3.23.12.2-1.23.6-3.63.6-3.61.22.2-0.0-2.2-1.2-0.6
BMI without tail1.54.67.52.41.42.22.72.52.72.7-2.62.62.2-0.42.4-2.42.5-2.51.42.3-0.4-2.3-0.5-1.1
Body weight4.519.928.95.24.04.85.45.05.45.4-5.35.34.3-3.15.4-5.35.4-5.43.24.0-1.8-3.7-0.3-0.7
Weight adjusted by age1.62.44.61.61.11.61.81.71.92.1-2.12.11.5-0.51.9-1.91.9-1.90.81.5-0.3-1.5-0.5-0.7
Bone surface0.00.10.5-0.7-0.2-0.0-0.00.00.10.1-0.50.40.00.50.0-0.00.1-0.1-0.10.10.2-0.1-0.7-0.5
Bone volume0.10.21.1-1.1-0.5-0.3-0.4-0.3-0.3-0.30.0-0.0-0.20.5-0.40.4-0.40.4-0.3-0.20.20.1-0.4-0.4
Breakpoint value in progressive ratio session0.00.00.10.10.1-0.0-0.0-0.1-0.2-0.2-0.3-0.2-0.10.10.1-0.10.1-0.10.0-0.2-0.00.3-0.10.2
Number of licking bursts0.91.42.81.51.51.51.21.41.21.2-1.71.11.5-0.30.4-0.30.4-0.41.51.4-1.2-1.31.1-0.9
Context. condit. distance diff. score0.50.52.7-0.3-1.3-0.6-0.5-0.4-0.5-0.50.6-0.6-0.31.7-0.90.9-0.90.8-0.5-0.00.7-0.3-0.2-0.9
Locomotion velocity, session 10.80.91.6-0.6-0.6-0.9-1.2-1.0-1.3-1.21.0-1.1-0.80.3-1.21.2-1.21.3-0.4-0.80.10.90.30.3
Locomotion distance, session 10.50.61.5-1.1-1.1-0.9-0.8-0.7-0.8-0.80.6-0.7-0.61.2-0.90.9-0.90.8-0.7-0.40.80.3-0.5-0.4
Locomotion velocity, session 24.45.19.5-1.5-1.2-2.1-2.8-2.5-2.8-2.82.6-3.1-2.10.1-2.82.8-2.92.9-1.2-2.2-0.12.30.91.4
Locomotion distance, session 22.83.85.9-2.3-2.4-2.4-2.2-2.3-2.2-2.21.8-2.2-2.21.8-1.71.7-1.71.7-2.1-1.91.81.6-1.20.4
Locomotion velocity, session 30.40.41.4-0.7-1.2-0.8-0.5-0.6-0.5-0.50.4-0.6-0.61.1-0.40.4-0.30.3-0.9-0.41.00.2-0.9-0.1
Locomotion distance, session 30.20.20.90.2-0.3-0.20.0-0.20.00.0-0.2-0.0-0.3-0.70.6-0.60.6-0.6-0.4-0.40.30.4-0.70.9
Stereotopy head waving bouts, day 30.40.51.5-0.2-0.3-0.2-0.5-0.2-0.5-0.50.5-0.40.01.2-1.21.2-1.21.20.20.2-0.1-0.30.6-1.0
Stereotopy head waving duration, day 30.60.74.7-0.4-0.7-0.4-0.4-0.2-0.4-0.40.3-0.20.12.2-1.21.2-1.11.1-0.00.40.4-0.60.1-1.7
Locomotion velocity, session 70.60.72.31.51.20.90.70.70.60.7-1.10.40.7-1.20.5-0.50.5-0.50.80.5-1.1-0.30.90.4
Locomotion distance, session 70.30.41.0-0.2-0.8-0.8-0.6-0.7-0.5-0.60.4-1.0-0.70.7-0.30.3-0.30.3-0.9-0.60.80.4-0.60.3
Stereotopy head waving bouts, day 71.21.42.21.20.51.11.51.31.51.5-1.41.41.10.11.4-1.41.5-1.50.61.20.1-1.3-0.5-0.7
Stereotopy head waving duration, day 71.92.33.71.60.81.51.91.71.91.9-1.81.81.50.21.6-1.61.7-1.70.91.7-0.1-1.8-0.5-1.0
Locomotion velocity, session 81.62.04.6-1.0-1.4-1.2-1.6-1.3-1.7-1.61.3-1.5-0.91.5-2.22.2-2.12.1-0.6-0.80.10.80.5-0.5
Locomotion distance, session 82.63.712.8-1.6-2.7-1.9-1.8-1.6-1.8-1.91.6-1.8-1.23.6-2.52.6-2.52.4-1.3-0.71.50.2-0.5-1.7
Degree of sensitization distance1.61.64.4-0.8-0.8-0.9-1.2-0.8-1.2-1.21.2-1.5-0.52.1-2.12.1-2.02.0-0.2-0.20.20.10.8-1.2
Degree of sensitization stereotypy1.61.73.11.30.71.31.71.51.81.6-1.51.51.30.01.6-1.61.7-1.70.71.3-0.0-1.4-0.6-0.7
Conditioned locomotion0.60.73.8-0.6-1.2-0.60.2-0.20.30.1-0.30.2-0.40.90.8-0.80.8-0.8-1.2-0.11.8-0.3-1.9-0.0
Cocaine response after cond. corrected1.01.12.0-1.0-1.0-1.3-1.2-1.3-1.2-1.21.2-1.3-1.4-0.2-0.40.4-0.50.5-1.4-1.40.81.4-0.71.3
Cocaine response after cond. not corrected0.50.51.9-0.4-0.4-0.8-0.8-0.9-0.7-0.70.8-0.8-1.0-0.7-0.00.0-0.10.1-0.9-1.10.31.1-0.41.4
Cocaine response before conditioning0.60.71.61.11.31.10.91.00.90.9-0.80.81.0-0.70.4-0.40.4-0.41.20.9-1.2-0.70.9-0.3
Saline control response0.20.21.0-0.4-0.2-0.3-0.4-0.4-0.4-0.51.0-0.6-0.4-0.1-0.50.5-0.50.5-0.1-0.4-0.20.40.30.3
Bone: connectivity density0.61.02.1-1.5-1.2-1.2-1.2-1.1-1.1-1.10.9-0.9-1.00.9-0.90.9-0.90.9-1.0-0.90.80.8-0.70.1
Bone: cortical apparent density0.50.71.6-0.2-0.00.50.90.70.90.9-1.21.30.60.41.0-1.01.1-1.10.20.70.4-0.8-1.0-0.8
Bone: cortical area4.16.39.92.92.52.93.02.82.92.9-3.12.92.5-2.22.6-2.62.6-2.62.32.2-1.8-1.90.9-0.4
Bone: cortical porosity0.40.51.90.2-0.2-0.6-0.8-0.7-0.7-0.70.7-1.0-0.8-0.9-0.20.1-0.20.2-0.5-0.90.11.00.21.4
Bone: cortical porosity0.10.10.50.6-0.0-0.2-0.2-0.2-0.1-0.10.2-0.4-0.3-0.40.1-0.10.1-0.1-0.3-0.30.20.30.10.7
Bone: cortical thickness3.04.98.12.61.72.42.72.42.62.6-2.82.72.1-1.82.7-2.72.7-2.71.71.9-1.0-1.70.2-0.2
Bone: cortical thickness0.70.83.3-0.4-1.6-0.50.30.00.30.2-0.40.4-0.21.70.7-0.70.7-0.8-0.90.21.8-0.6-1.8-0.8
Bone: cortical tissue density0.50.71.5-0.3-0.10.50.90.70.90.9-1.21.20.50.41.0-1.01.1-1.10.10.70.5-0.8-1.0-0.7
Condit. Reinf. active minus inactive responses0.80.92.1-1.0-0.8-1.1-1.0-1.2-1.0-1.00.7-1.1-1.3-0.5-0.10.1-0.20.2-1.1-1.40.61.4-0.61.4
Condit. Reinf. active-inactive response ratio1.81.93.1-1.5-1.3-1.7-1.7-1.7-1.7-1.71.4-1.7-1.70.1-0.90.9-1.01.0-1.4-1.80.81.8-0.41.2
Condit. Reinf. active responses0.20.30.5-0.7-0.6-0.7-0.6-0.7-0.6-0.60.1-0.6-0.70.2-0.20.2-0.20.2-0.7-0.70.50.7-0.50.4
Condit. Reinf. inactive responses0.81.02.10.90.91.21.21.21.11.2-1.51.31.30.40.4-0.40.5-0.51.11.3-0.6-1.30.3-1.3
Incentive salience index mean0.20.20.9-0.40.0-0.3-0.2-0.4-0.2-0.2-0.1-0.2-0.5-0.80.4-0.50.4-0.4-0.4-0.60.10.8-0.40.9
Condit. Reinf. lever presses0.40.61.20.30.60.81.00.80.91.0-1.11.10.7-0.31.0-1.01.0-1.00.40.6-0.2-0.5-0.3-0.3
Condit. Reinf. active minus inactive responses0.40.51.40.80.80.80.50.80.50.5-0.30.41.00.4-0.40.4-0.30.31.11.0-0.9-0.91.0-1.2
Condit. Reinf. active-inactive response ratio0.10.20.5-0.5-0.5-0.4-0.2-0.3-0.2-0.20.3-0.1-0.50.20.3-0.30.3-0.3-0.7-0.40.60.3-0.70.3
Condit. Reinf. active responses0.20.30.80.00.10.0-0.4-0.1-0.3-0.40.4-0.40.10.5-0.90.9-0.90.90.40.1-0.5-0.10.7-0.7
Condit. Reinf. inactive responses0.30.41.3-0.1-0.0-0.1-0.5-0.2-0.5-0.40.3-0.40.10.5-1.11.1-1.11.10.40.1-0.5-0.10.8-0.7
Condit. Reinf. lever presses0.20.30.60.60.60.60.60.70.70.7-0.40.50.70.30.3-0.30.4-0.40.50.8-0.2-0.80.2-0.7
Condit. Reinf. lever reinforcers received0.00.10.30.10.10.0-0.10.0-0.1-0.10.3-0.20.10.5-0.40.4-0.40.40.20.1-0.2-0.10.2-0.5
Conditioned reinforcement - actives0.50.92.70.50.50.50.90.50.90.8-1.00.90.2-1.21.6-1.71.6-1.6-0.00.00.10.1-0.90.8
Conditioned reinforcement - inactives0.71.02.30.91.30.90.90.70.90.9-1.11.10.5-1.51.5-1.51.4-1.40.60.2-0.80.00.20.6
Conditioned locomotion0.91.22.31.41.01.11.31.01.31.2-1.31.10.8-1.01.5-1.51.5-1.50.50.6-0.7-0.4-0.20.4
Patch foraging indifference point 0 sec0.10.20.90.20.30.40.30.40.30.3-0.20.20.50.4-0.10.1-0.00.00.50.5-0.4-0.40.5-0.9
Patch foraging indifference point AUC0.20.30.9-0.10.3-0.2-0.5-0.4-0.5-0.50.3-0.6-0.2-0.4-0.70.7-0.70.80.1-0.3-0.60.40.90.4
Delay disc. indifference point, 0s delay2.93.211.1-0.0-1.5-0.70.7-0.20.60.7-0.61.0-0.9-0.33.1-3.13.0-3.0-1.7-0.92.50.7-3.31.2
Delay disc. indifference point, 16s delay0.91.04.9-0.30.2-0.4-0.3-0.6-0.3-0.30.20.0-0.9-2.21.1-1.21.0-1.0-0.7-1.20.11.5-0.52.2
Delay disc. indifference point, 2s delay1.31.43.6-0.0-1.0-0.70.0-0.50.10.0-0.30.3-1.0-1.31.8-1.81.7-1.7-1.3-1.01.50.9-1.91.9
Delay disc. indifference point, 24s delay1.11.33.8-0.3-0.5-0.40.4-0.20.30.4-0.50.7-0.6-1.21.9-2.01.9-1.9-1.0-0.71.30.7-1.91.4
Delay disc. indifference point, 4s delay0.80.82.2-0.6-0.3-0.6-0.3-0.7-0.5-0.30.20.0-1.0-1.11.2-1.21.1-1.1-0.9-1.30.61.5-1.01.5
Delay disc. indifference point, 8s delay0.70.92.50.70.90.91.00.80.71.0-0.71.20.6-1.61.3-1.31.3-1.30.60.4-0.5-0.1-0.10.6
Indifference point function ln k0.10.30.8-0.4-0.2-0.3-0.6-0.5-0.6-0.60.9-0.6-0.4-0.2-0.60.6-0.70.7-0.0-0.5-0.30.50.40.3
Indifference point function log k0.10.30.8-0.4-0.2-0.3-0.6-0.5-0.6-0.60.9-0.6-0.4-0.2-0.60.6-0.70.7-0.0-0.5-0.30.50.40.3
Patch foraging total patch changes 0 sec0.10.20.60.40.60.60.40.50.40.4-0.30.30.60.1-0.00.00.0-0.00.70.5-0.6-0.40.7-0.8
Patch foraging total patch changes 12 sec0.40.50.90.70.60.70.80.80.80.8-0.90.80.70.00.7-0.70.7-0.70.50.7-0.3-0.70.1-0.7
Patch foraging total patch changes 18 sec0.10.10.30.50.50.50.30.40.30.3-0.30.10.5-0.1-0.10.1-0.10.10.40.4-0.6-0.30.5-0.3
Patch foraging total patch changes 24 sec0.40.74.7-0.1-1.00.10.50.50.50.5-0.40.40.52.20.00.00.1-0.1-0.21.01.0-1.3-0.8-1.7
Patch foraging total patch changes 6 sec0.40.62.30.91.51.00.50.70.50.5-0.60.40.8-0.9-0.00.0-0.00.01.20.6-1.4-0.31.4-0.2
Patch foraging time to switch 0 sec1.02.04.70.5-0.70.51.41.11.41.4-1.51.50.92.21.4-1.41.5-1.6-0.31.41.6-1.8-2.1-1.8
Patch foraging water rate 0 sec1.02.19.01.42.51.50.40.80.40.4-0.40.41.1-2.7-0.50.5-0.50.62.20.5-3.0-0.03.00.7
Patch foraging water rate 12 sec0.20.52.30.41.00.5-0.10.1-0.1-0.10.4-0.20.3-1.0-0.70.7-0.70.70.90.1-1.40.21.50.4
Patch foraging water rate 18 sec0.50.82.50.70.90.90.40.80.40.4-0.20.41.10.2-0.80.8-0.70.71.51.0-1.3-0.91.6-1.1
Patch foraging water rate 24 sec1.62.27.41.52.31.80.81.40.80.8-0.60.71.7-1.2-0.70.8-0.70.72.51.4-2.7-1.12.7-0.9
Patch foraging water rate 6 sec1.72.46.11.92.12.01.21.71.21.2-1.21.22.0-1.0-0.20.3-0.20.22.51.7-2.5-1.42.3-0.9
Seeking ratio, delayed vs. immediate footshock1.62.04.0-1.20.1-0.8-1.5-1.3-1.7-1.71.8-1.7-1.0-0.3-1.91.9-2.02.0-0.2-1.3-1.21.51.30.8
Distance traveled before self-admin0.91.21.8-0.8-1.1-1.3-1.3-1.3-1.3-1.31.2-1.3-1.30.7-0.80.8-0.80.8-1.2-1.20.91.2-0.60.7
Distance traveled after self-admin0.50.63.1-0.6-1.0-0.8-0.3-0.6-0.3-0.30.1-0.4-0.80.60.6-0.60.6-0.6-1.2-0.71.40.5-1.80.7
Extensor digitorum longus weight2.610.419.03.94.43.83.63.53.63.5-4.03.53.2-3.53.0-3.03.0-3.03.22.7-2.9-2.21.60.0
Bone: elastic displacement0.50.61.30.80.40.90.81.00.90.9-1.10.91.00.30.2-0.20.3-0.30.91.1-0.4-1.20.4-1.1
Bone: elastic work2.83.76.22.31.72.42.12.42.22.2-2.32.12.5-0.10.9-0.80.9-1.02.42.5-1.5-2.41.3-1.9
Bone: endosteal estimation0.61.22.31.51.31.41.01.31.01.1-1.20.91.50.2-0.10.1-0.0-0.01.51.4-1.3-1.31.3-1.3
Bone: endosteal perimeter0.61.33.51.31.91.41.01.21.11.1-1.31.11.2-1.20.6-0.60.6-0.61.41.0-1.6-0.71.2-0.2
Epididymis fat weight1.55.19.22.71.82.22.72.42.82.6-2.42.51.9-2.03.0-3.03.0-3.01.21.8-0.5-1.7-0.40.4
Delta time in closed arm before/after self-admin1.00.93.2-1.1-1.8-1.1-0.8-0.9-0.8-0.80.7-0.8-0.81.7-0.60.6-0.60.6-1.0-0.51.40.4-0.9-0.5
Delta time in open arm before/after self-admin1.61.63.51.41.61.11.21.01.21.2-1.31.30.7-1.81.9-1.91.8-1.80.60.4-0.6-0.1-0.00.8
Diff in mean of infusions in LGA sessions1.41.74.1-1.9-1.8-1.8-1.2-1.5-1.2-1.21.0-1.0-1.61.4-0.20.2-0.30.2-1.8-1.32.01.1-1.70.2
Delay discount exponential model param1.51.65.1-0.2-0.10.1-0.50.1-0.3-0.50.6-0.80.62.3-2.22.2-2.12.10.70.8-0.7-1.01.4-2.1
Extinction: sum of active levers before priming0.70.82.20.30.60.61.00.71.01.0-1.11.10.5-0.71.5-1.51.5-1.50.20.40.1-0.4-0.80.2
Active lever presses in extinction session 60.50.52.0-0.1-0.7-0.40.1-0.20.10.1-0.20.1-0.5-0.11.1-1.11.1-1.1-0.9-0.51.10.4-1.40.8
Bone: final force2.94.77.42.71.72.52.62.72.62.6-2.62.42.60.21.5-1.51.6-1.62.22.7-1.1-2.70.9-2.1
Bone: final moment2.64.27.82.81.92.52.42.52.42.4-2.42.12.6-0.11.2-1.21.3-1.32.32.6-1.5-2.41.3-1.8
Food consumed during 24 hour testing period0.50.73.20.81.10.6-0.20.2-0.2-0.20.3-0.00.4-1.1-0.90.9-0.90.91.10.1-1.80.21.80.2
Glucose1.82.923.01.12.40.6-0.4-0.3-0.5-0.40.1-0.3-0.3-4.80.3-0.40.2-0.10.8-1.2-2.61.92.33.4
Heart weight0.81.33.31.51.71.31.21.21.11.2-0.91.01.0-1.81.0-1.01.0-1.01.00.8-1.1-0.60.80.5
Delay discount hyperbolic model param1.51.65.0-0.10.00.2-0.40.1-0.3-0.40.6-0.80.72.2-2.22.2-2.12.10.80.9-0.8-1.11.5-2.1
Intermittent access intake day 1-15 change2.04.18.5-1.7-1.4-2.2-2.3-2.4-2.3-2.42.4-2.6-2.5-1.4-1.11.1-1.21.2-2.0-2.60.92.7-0.32.9
Intermittent access intake escalation1.42.97.7-1.3-0.9-1.8-2.0-2.0-1.9-1.92.0-2.1-2.1-1.6-0.80.8-0.90.9-1.6-2.20.62.4-0.12.8
Intermittent access intake escalation 22.02.34.7-1.2-0.6-1.5-1.8-1.7-1.8-1.82.0-2.2-1.6-1.0-1.41.4-1.41.5-1.0-1.70.21.80.62.0
Intermitt. access day 1 inactive lever presses0.10.51.6-0.90.2-0.5-0.7-0.7-0.6-0.70.8-0.5-0.8-1.2-0.00.0-0.10.1-0.3-1.0-0.21.10.21.3
Intermitt. access day 15 inactive lever presses0.51.15.2-0.30.4-0.5-0.9-0.9-0.9-0.90.9-0.8-1.0-2.3-0.20.1-0.30.3-0.4-1.4-0.71.60.72.3
Intermitt. access escalation Index0.71.02.2-1.0-1.1-1.2-1.1-1.1-1.2-1.11.2-1.3-1.01.5-1.01.0-1.01.0-0.8-0.80.90.8-0.2-0.4
Intermittent access day 1 total infusions0.71.13.40.30.20.51.10.71.21.1-1.21.20.4-0.01.8-1.81.8-1.8-0.10.40.5-0.4-1.4-0.1
Intermittent access day 15 total infusions0.30.52.3-0.20.3-0.2-0.1-0.3-0.0-0.10.0-0.1-0.6-1.51.0-1.00.9-0.9-0.4-0.80.11.1-0.51.5
Intermittent access terminal intake (last 3 days)0.20.31.6-0.40.3-0.3-0.4-0.5-0.2-0.30.3-0.3-0.6-1.20.4-0.40.3-0.3-0.3-0.8-0.11.0-0.11.3
Intermittent access total infusions0.30.41.50.10.70.30.30.10.40.3-0.40.4-0.1-1.21.0-1.00.9-0.90.1-0.3-0.40.5-0.10.9
Intermittent access day 1 locomotion0.40.51.00.50.20.70.90.81.00.9-1.01.00.60.30.9-0.91.0-1.00.20.7-0.0-0.7-0.6-0.4
Intermittent access day 15 total locomotion0.61.13.70.50.50.30.70.20.70.6-0.50.6-0.2-1.61.9-1.91.8-1.8-0.4-0.50.10.6-1.01.6
Intermittent access total locomotion0.50.63.20.30.50.20.2-0.10.20.1-0.10.2-0.3-1.81.0-1.00.9-0.9-0.3-0.6-0.40.8-0.21.7
Intermittent access standard deviation0.20.51.0-0.6-0.5-0.8-0.9-0.8-0.7-0.81.0-1.0-0.8-0.1-0.40.4-0.40.5-0.6-0.90.30.90.00.7
Left kidney weight3.315.323.44.83.74.74.84.84.74.8-4.44.44.6-1.13.2-3.23.3-3.33.74.6-2.3-4.41.1-2.5
Right kidney weight2.511.318.54.02.43.74.34.04.24.2-3.73.93.6-0.93.6-3.53.6-3.72.53.7-1.0-3.7-0.2-1.8
Cocaine induced anxiety0.81.14.80.00.9-0.5-0.9-1.0-1.0-0.90.6-1.0-1.0-2.1-0.10.1-0.30.3-0.3-1.5-0.91.90.82.2
Post-drug Anxiety0.80.94.2-0.2-0.0-0.7-0.3-0.8-0.5-0.40.2-0.5-1.1-1.50.9-0.90.8-0.8-1.0-1.30.51.4-0.92.0
Baseline Anxiety1.82.15.50.4-0.90.51.71.11.61.5-1.31.50.81.02.0-2.02.0-2.1-0.41.11.7-1.5-2.3-0.9
Tail length0.93.57.12.62.72.41.92.01.81.8-1.71.72.1-2.41.0-1.01.0-1.02.21.6-2.7-1.21.80.2
Length with tail2.711.820.44.54.34.33.84.03.83.8-3.73.73.9-2.92.5-2.52.6-2.63.83.5-3.5-3.02.1-0.8
Length without tail2.06.39.83.12.93.02.92.92.93.0-2.82.82.7-2.02.4-2.42.4-2.42.52.5-1.7-2.30.8-0.6
Times rat made contact with spout0.91.12.6-0.50.0-0.5-1.2-0.8-1.2-1.21.2-1.0-0.5-0.4-1.61.6-1.61.60.2-0.7-1.00.91.30.5
Lifetime Intake0.30.41.80.10.90.40.30.20.50.3-0.50.50.1-1.40.9-0.90.8-0.80.2-0.2-0.70.40.10.9
Liver weight, left0.20.40.80.90.40.80.90.80.70.8-0.60.70.8-0.30.6-0.60.6-0.60.40.8-0.3-0.70.0-0.3
Liver weight, right2.44.27.22.21.42.32.52.62.42.6-2.42.52.50.41.4-1.41.5-1.61.82.7-0.8-2.60.1-2.1
Locomotor activity0.71.15.61.01.71.00.10.50.10.1-0.1-0.10.8-1.4-0.91.0-1.01.01.50.5-2.2-0.22.4-0.0
Locomotor testing distance0.71.22.41.41.61.41.11.21.11.1-1.01.01.2-1.50.7-0.70.7-0.71.20.9-1.4-0.71.10.1
Locomotor testing rearing1.22.56.72.12.62.01.41.71.51.5-1.41.31.7-1.90.8-0.80.8-0.82.01.3-2.3-0.91.9-0.2
Locomotion in novel chamber0.50.61.4-0.3-1.2-1.0-0.9-0.9-0.9-0.80.9-1.0-1.00.5-0.30.3-0.40.4-1.0-0.90.90.8-0.40.3
Locomotion in novel chamber post-restriction0.40.62.9-0.6-1.7-0.9-0.5-0.6-0.5-0.60.5-0.3-0.61.4-0.30.3-0.20.2-1.2-0.41.20.1-1.3-0.3
Fecal boli incidents, locomotor time 10.30.40.8-0.20.2-0.4-0.9-0.6-0.9-0.70.8-0.9-0.50.3-0.90.9-0.90.9-0.1-0.6-0.50.80.70.1
Change in fecal boli incidents, locomotor task0.50.51.3-0.4-0.6-0.4-0.7-0.5-0.8-0.70.7-0.7-0.30.8-1.21.2-1.11.1-0.1-0.2-0.10.20.7-0.3
Time >=10cm from walls, locomotor time 11.61.73.50.7-0.90.41.31.01.41.4-1.21.40.71.51.6-1.61.7-1.7-0.21.11.6-1.5-1.9-1.4
Bouts of movement, locomotor time 10.30.31.4-0.0-0.6-0.20.30.10.00.4-0.00.4-0.1-0.10.8-0.80.8-0.8-0.50.01.0-0.1-1.20.2
Total resting periods, locomotor time 10.30.31.20.3-0.6-0.10.30.10.10.4-0.10.3-0.2-0.50.9-0.90.9-0.9-0.6-0.01.0-0.1-1.10.6
Rest time, locomotor task time 11.21.53.61.91.31.51.31.51.31.3-1.31.31.5-1.10.5-0.40.5-0.51.41.5-1.0-1.50.9-0.4
Distance moved, locomotor task time 10.10.10.7-0.6-0.3-0.2-0.2-0.3-0.2-0.20.1-0.1-0.20.8-0.20.2-0.20.2-0.1-0.2-0.00.30.0-0.6
Vertical activity count, locomotor time 10.41.02.3-1.5-1.0-1.1-1.1-1.1-1.1-1.21.0-0.9-0.91.4-1.01.0-1.01.0-0.7-0.90.40.9-0.1-0.3
Time >=10cm from walls, locomotor time 20.50.71.60.60.30.71.10.91.00.9-1.01.00.90.80.7-0.70.7-0.80.51.10.1-1.3-0.4-1.1
Bouts of movement, locomotor time 20.10.20.5-0.5-0.0-0.4-0.2-0.3-0.4-0.00.3-0.2-0.5-0.30.6-0.60.6-0.6-0.7-0.60.60.6-0.70.6
Total resting periods, locomotor time 20.10.20.8-0.3-0.0-0.10.2-0.0-0.00.2-0.10.2-0.2-0.40.9-0.90.8-0.8-0.4-0.30.50.3-0.80.5
Rest time, locomotor task time 21.01.32.91.10.61.31.31.41.31.1-1.51.71.5-0.40.3-0.20.3-0.31.31.6-0.8-1.70.5-0.9
Distance moved, locomotor task time 20.50.62.2-1.0-1.0-0.9-0.8-0.8-0.8-0.80.8-0.9-0.81.5-0.50.5-0.50.5-0.9-0.80.70.7-0.4-0.5
Vertical activity count, locomotor time 21.11.62.6-1.4-1.3-1.5-1.4-1.5-1.6-1.51.5-1.6-1.61.1-0.70.7-0.70.7-1.4-1.51.01.5-0.60.4
Light reinforcement 11.43.55.12.11.92.12.32.22.32.3-2.22.22.1-0.11.6-1.61.6-1.61.62.2-0.9-2.10.4-1.7
Light reinforcement 21.82.74.81.91.62.01.92.11.92.0-1.71.82.10.40.9-0.80.9-0.91.82.2-1.0-2.20.8-1.8
Bone: marrow area0.51.01.81.31.11.20.91.20.91.0-1.10.81.30.3-0.00.10.0-0.01.31.3-1.1-1.21.2-1.3
Bone: maximum diameter3.66.711.73.03.43.12.82.82.82.8-3.22.92.7-2.82.3-2.22.2-2.22.82.2-2.6-1.71.7-0.1
Bone: maximum force2.24.06.52.31.72.42.32.52.32.4-2.32.32.50.21.1-1.11.2-1.22.22.6-1.3-2.51.0-2.1
Bone: maximum moment2.03.65.92.42.02.42.12.42.12.1-2.02.02.4-0.10.8-0.80.9-0.92.32.4-1.7-2.21.5-1.8
Mean time between licks in bursts0.71.74.4-0.60.2-0.6-1.4-1.0-1.4-1.41.2-1.5-0.6-0.2-2.12.1-2.12.10.3-0.8-1.00.91.70.3
Mean num. licks in bursts1.82.86.0-1.8-1.5-1.8-2.0-2.0-2.0-2.02.5-1.8-1.90.1-1.51.4-1.51.5-1.4-1.90.61.9-0.31.3
Cd content in liver0.10.10.5-0.00.2-0.2-0.4-0.3-0.4-0.40.2-0.3-0.3-0.7-0.30.3-0.30.3-0.0-0.4-0.40.50.40.6
Co content in liver0.40.42.50.90.60.20.30.10.30.3-0.10.1-0.1-1.60.9-0.90.8-0.8-0.0-0.3-0.20.40.01.4
Cu content in liver1.11.32.6-1.2-1.3-1.5-1.3-1.5-1.3-1.41.5-1.1-1.60.1-0.40.4-0.50.5-1.2-1.61.01.6-0.10.8
Fe content in liver3.44.17.0-1.7-2.6-2.6-2.3-2.5-2.3-2.32.4-2.2-2.60.9-0.90.9-1.01.0-2.4-2.52.12.3-1.11.2
K content in liver0.80.82.1-0.6-0.0-0.6-0.1-0.5-0.1-0.10.3-0.2-0.9-0.91.3-1.31.2-1.2-0.9-1.01.01.1-1.01.4
Mg content in liver1.11.13.10.91.10.81.10.81.11.1-1.10.90.5-1.11.8-1.81.7-1.70.40.4-0.1-0.2-0.10.5
Mn content in liver0.40.51.2-0.8-0.0-0.6-0.8-0.7-0.8-0.81.1-0.9-0.7-0.2-0.60.6-0.70.7-0.1-0.8-0.20.90.50.5
Na content in liver1.71.88.4-0.4-0.2-1.0-0.7-1.1-0.7-0.70.9-0.9-1.6-2.01.2-1.31.1-1.1-1.4-1.90.72.1-1.12.9
Rb content in liver0.10.10.50.50.30.10.30.20.30.3-0.20.2-0.0-0.40.7-0.70.7-0.70.0-0.10.10.20.00.3
Se content in liver0.30.42.3-0.10.4-0.00.0-0.20.00.00.40.1-0.4-1.50.8-0.80.7-0.7-0.1-0.6-0.20.80.11.3
Sr content in liver2.52.14.91.82.11.81.41.51.41.4-1.41.41.4-2.21.2-1.21.1-1.11.71.0-1.9-0.61.20.4
Zn content in liver0.60.72.20.81.31.00.60.80.60.6-0.50.50.9-1.0-0.00.0-0.00.01.30.7-1.5-0.41.4-0.2
Bone: minimum diameter0.71.32.41.41.21.51.11.41.11.1-1.51.21.5-0.10.2-0.20.2-0.21.51.4-1.3-1.31.2-1.2
Time in familiar zone, hab. session 10.80.72.3-0.6-0.8-0.8-0.8-0.7-0.8-0.81.2-1.2-0.51.5-1.11.1-1.11.0-0.6-0.30.80.1-0.1-0.5
Time in novel zone, hab. session 10.70.72.10.71.01.00.80.80.80.8-1.01.10.8-1.50.7-0.70.6-0.60.90.5-1.2-0.30.60.2
Total zone transitions, hab. session 10.20.20.6-0.6-0.5-0.4-0.5-0.4-0.5-0.50.1-0.4-0.30.8-0.60.6-0.60.6-0.2-0.20.20.1-0.2-0.3
Total locomotion distance, hab. session 10.50.71.5-1.2-0.4-0.9-1.1-1.0-1.1-1.11.0-1.1-0.90.2-0.80.8-0.90.9-0.6-1.00.21.0-0.20.5
Locomotion velocity, hab. session 10.30.51.2-1.1-0.6-0.8-0.8-0.8-0.8-0.80.7-0.8-0.80.5-0.60.6-0.60.6-0.6-0.80.40.8-0.50.3
Time in familiar zone, hab. session 23.23.37.1-2.4-2.5-2.2-1.9-1.9-1.8-1.91.7-1.8-1.82.7-1.61.6-1.61.5-2.0-1.42.01.0-1.3-0.5
Time in novel zone, hab. session 26.26.311.23.23.33.22.72.82.72.7-2.62.72.7-2.91.9-1.91.9-1.92.92.3-2.8-1.91.8-0.1
Total zone transitions, hab. session 20.10.10.50.30.60.50.20.40.20.3-0.50.40.4-0.40.0-0.00.00.00.60.3-0.7-0.20.5-0.2
Total locomotion distance, hab. session 20.20.21.30.31.00.50.10.20.00.1-0.20.30.3-0.8-0.20.2-0.20.20.80.1-1.10.20.90.1
Locomotion velocity, hab. session 20.10.20.90.20.80.40.00.10.00.0-0.10.20.2-0.9-0.00.0-0.00.10.5-0.1-0.90.40.70.4
Novel to familiar place preference ratio0.50.62.9-0.6-0.2-0.5-0.4-0.6-0.4-0.40.5-0.4-0.8-1.50.6-0.60.5-0.5-0.7-1.00.31.2-0.71.7
Novelty place preference0.40.53.0-0.40.1-0.2-0.3-0.4-0.3-0.30.4-0.2-0.6-1.70.5-0.60.5-0.4-0.4-0.8-0.11.0-0.31.6
Time in novel zone, NPP test0.40.43.1-0.20.4-0.1-0.1-0.2-0.1-0.10.3-0.1-0.4-1.80.5-0.50.4-0.4-0.1-0.6-0.30.8-0.21.5
Total zone transitions, NPP test0.10.10.6-0.6-0.4-0.4-0.2-0.3-0.2-0.2-0.0-0.2-0.40.60.0-0.10.0-0.0-0.5-0.30.60.2-0.7-0.1
Total locomotion distance, NPP test0.40.51.1-1.1-0.6-0.9-0.7-0.9-0.7-0.70.5-0.6-1.00.20.1-0.10.0-0.0-1.0-1.00.81.0-0.90.6
Locomotion velocity, NPP test0.71.02.0-1.3-0.9-1.3-1.0-1.2-1.0-1.00.7-0.9-1.40.10.1-0.10.1-0.1-1.4-1.41.11.4-1.21.0
Intraocular pressure0.30.51.00.70.60.81.00.80.90.5-0.80.80.8-0.90.3-0.30.4-0.40.90.8-0.6-0.80.50.1
Delta distance traveled before/after self-admin0.70.82.4-0.1-0.20.20.80.50.80.8-0.70.80.2-0.11.5-1.51.5-1.5-0.40.30.9-0.4-1.50.2
Delta ambulatory time before/after self-admin0.30.41.4-0.8-0.8-0.6-0.2-0.5-0.3-0.30.2-0.4-0.60.20.4-0.40.4-0.4-0.9-0.51.00.4-1.20.5
Parametrial fat weight0.40.84.2-0.3-0.2-0.7-0.6-0.9-0.6-0.60.8-0.7-1.1-1.60.5-0.60.5-0.4-1.0-1.30.31.5-0.22.0
Pavlov. Cond. lever latency0.50.71.4-0.1-0.1-0.7-1.0-0.9-1.0-1.01.0-1.2-0.9-0.7-0.70.7-0.80.8-0.5-1.0-0.11.00.51.2
Pavlov. Cond. magazine entry latency0.60.82.4-1.4-1.2-0.7-0.8-0.6-0.8-0.80.8-0.6-0.41.6-1.21.2-1.21.2-0.3-0.20.30.2-0.0-1.1
Pavlov. Cond. change in total contacts0.20.20.7-0.8-0.4-0.3-0.1-0.3-0.1-0.1-0.00.1-0.4-0.50.4-0.40.4-0.4-0.4-0.50.30.6-0.70.5
Pavlov. Cond. index score0.30.42.1-1.3-1.1-0.4-0.2-0.2-0.3-0.20.20.1-0.21.5-0.40.4-0.30.3-0.40.00.7-0.1-0.7-1.1
Pavlov. Cond. latency score0.30.32.0-1.1-0.9-0.20.0-0.0-0.1-0.00.00.30.11.4-0.20.2-0.20.2-0.20.20.6-0.4-0.6-1.2
Pavlov. Cond. lever contacts0.30.41.4-0.2-0.40.40.70.60.60.7-0.60.80.60.90.4-0.40.5-0.50.20.70.3-0.8-0.6-1.2
Pavlov. Cond. magazine entry number0.91.12.81.71.41.11.11.11.21.1-1.11.00.9-1.31.1-1.11.1-1.10.80.8-0.7-0.70.30.4
Pavlov. Cond. intertrial magazine entries0.50.61.91.30.80.70.80.60.80.8-0.90.70.4-1.41.0-1.01.0-1.00.30.3-0.3-0.30.10.8
Pavlov. Cond. lever-magazine prob. diff.0.30.42.3-1.2-1.1-0.3-0.1-0.1-0.2-0.10.10.2-0.01.5-0.30.3-0.30.3-0.30.10.6-0.3-0.7-1.2
Pavlov. Cond. response bias0.20.31.1-1.0-0.9-0.5-0.4-0.4-0.4-0.40.3-0.2-0.40.9-0.30.3-0.30.3-0.4-0.30.50.3-0.4-0.5
Pavlov. Cond. lever latency0.50.71.81.00.40.70.90.70.90.9-1.31.00.5-0.81.2-1.21.2-1.20.20.4-0.1-0.4-0.30.4
Pavlov. Cond. magazine entry latency0.91.11.81.20.91.11.31.31.31.3-0.91.01.2-0.01.0-1.01.0-1.00.91.3-0.3-1.30.2-0.9
Pavlov. Cond. change in total contacts0.00.10.4-0.20.30.10.10.10.10.10.3-0.00.20.6-0.10.1-0.10.10.10.30.1-0.30.1-0.6
Pavlov. Cond. index score0.10.10.6-0.20.10.10.10.20.10.10.4-0.10.30.6-0.30.3-0.20.20.20.40.0-0.40.2-0.8
Pavlov. Cond. latency score0.10.10.8-0.20.00.10.00.20.10.10.4-0.10.30.7-0.30.3-0.30.30.20.40.1-0.50.2-0.9
Pavlov. Cond. lever contacts0.81.12.3-1.4-0.8-1.1-1.2-1.1-1.2-1.21.5-1.3-0.90.9-1.31.2-1.31.2-0.6-0.80.50.70.0-0.1
Pavlov. Cond. magazine entry number1.41.73.1-1.4-1.4-1.6-1.5-1.7-1.6-1.61.3-1.3-1.7-0.3-0.60.6-0.70.7-1.4-1.80.81.8-0.71.6
Pavlov. Cond. intertrial magazine entries0.60.92.0-1.0-0.6-1.0-1.1-1.2-1.2-1.20.9-1.1-1.2-0.6-0.70.7-0.70.8-0.7-1.30.11.40.11.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.9-0.10.20.20.20.30.20.20.30.00.40.7-0.30.3-0.20.20.30.50.0-0.60.2-1.0
Pavlov. Cond. response bias0.10.10.5-0.4-0.1-0.2-0.3-0.2-0.2-0.20.7-0.4-0.10.7-0.50.5-0.50.4-0.00.00.2-0.10.1-0.6
Time in closed arm before self-admin0.20.20.60.30.60.60.30.50.30.3-0.40.50.7-0.1-0.40.4-0.30.30.70.6-0.7-0.60.6-0.5
Time in closed arm after self-admin0.30.31.4-0.5-0.8-0.5-0.5-0.4-0.5-0.50.3-0.3-0.31.2-0.80.8-0.80.8-0.3-0.10.5-0.0-0.2-0.7
Time in open arm before self-admin0.20.20.60.60.10.50.40.50.40.4-0.30.20.60.4-0.10.1-0.00.00.60.6-0.3-0.60.4-0.8
Time in open arm after self-admin0.91.01.71.31.01.11.11.11.21.2-1.11.11.0-0.91.1-1.11.1-1.10.80.8-0.6-0.70.3-0.1
Bone: periosteal estimation2.04.37.12.52.22.62.42.52.42.4-2.72.32.5-0.81.4-1.41.4-1.42.32.3-1.8-2.11.3-1.4
Bone: periosteal perimeter2.44.16.72.32.32.32.32.22.32.3-2.62.32.0-1.92.1-2.12.1-2.11.81.7-1.5-1.40.8-0.2
Bone: post-yield work0.30.40.9-0.60.3-0.3-0.7-0.5-0.7-0.71.0-0.7-0.4-0.1-0.90.9-0.90.9-0.0-0.5-0.50.60.60.2
Progressive ratio test 1 active lever presses0.91.12.90.31.00.81.10.81.11.0-1.21.30.5-0.91.7-1.71.7-1.60.50.3-0.3-0.1-0.40.1
Progressive ratio test 1 breakpoint0.91.13.00.31.00.81.10.81.11.0-1.21.30.5-0.91.7-1.71.7-1.70.40.3-0.3-0.1-0.50.1
Progressive ratio test 1 inactive lever presses0.71.05.30.41.40.60.60.30.60.5-0.60.50.0-2.31.5-1.51.4-1.40.4-0.4-0.70.70.21.5
Progressive ratio test 2 active lever presses0.30.41.0-0.50.0-0.10.3-0.10.30.1-0.20.5-0.3-0.91.0-1.01.0-0.9-0.4-0.40.30.5-0.90.9
Progressive ratio test 2 breakpoint0.30.41.0-0.4-0.0-0.10.3-0.00.30.2-0.20.6-0.3-0.91.0-1.01.0-1.0-0.4-0.40.40.4-0.90.8
Progressive ratio test 2 inactive lever presses0.61.03.30.40.90.50.80.40.80.7-0.80.90.1-1.81.7-1.71.6-1.60.1-0.2-0.20.4-0.51.2
Incentive Sensitization - Responses0.20.30.8-0.7-0.6-0.5-0.2-0.5-0.2-0.30.30.1-0.6-0.70.4-0.50.4-0.4-0.7-0.60.70.6-0.90.9
Incentive Sensitization - Breakpoint0.20.20.7-0.6-0.5-0.5-0.2-0.4-0.2-0.20.20.1-0.5-0.60.4-0.40.4-0.4-0.6-0.50.70.4-0.80.7
Sum of active levers in priming session hrs 5-60.50.42.0-0.6-0.4-0.40.1-0.20.00.0-0.2-0.0-0.5-0.10.9-1.00.9-0.9-0.8-0.41.00.4-1.40.7
Progressive ratio0.10.10.30.40.00.30.30.30.30.3-0.40.50.2-0.20.4-0.30.3-0.30.10.2-0.3-0.1-0.2-0.0
Food seeking constrained by brief footshock1.21.53.40.61.21.11.41.01.31.1-1.41.50.8-1.81.8-1.81.7-1.70.70.6-0.5-0.3-0.30.8
Seeking ratio, punishment vs. effort0.10.11.3-0.30.70.10.10.00.1-0.0-0.00.1-0.0-1.10.3-0.30.3-0.20.3-0.1-0.30.30.30.7
Retroperitoneal fat weight0.31.33.91.00.10.51.10.81.21.2-0.81.10.4-0.92.0-2.02.0-2.0-0.40.40.7-0.4-1.20.9
Reaction time number correct1.83.410.21.92.72.31.21.81.11.2-0.81.02.3-1.0-0.80.8-0.80.83.02.0-3.1-1.63.2-1.5
Reaction time mean minus median0.41.01.7-1.2-0.9-1.2-1.3-1.3-1.2-1.31.3-1.2-1.20.4-0.80.8-0.90.9-0.9-1.20.51.3-0.30.5
Reaction time mean minus median AUC0.10.10.40.20.10.20.40.30.40.4-0.30.40.20.20.7-0.70.7-0.7-0.00.20.2-0.1-0.5-0.3
Reaction time num false alarms1.31.85.00.5-0.60.21.20.71.21.2-1.51.20.2-0.02.2-2.22.2-2.2-0.80.41.5-0.6-2.10.1
Reaction time num false alarms AUC1.62.46.10.8-0.40.61.71.21.71.7-1.91.60.70.22.4-2.42.5-2.5-0.51.01.5-1.2-2.1-0.4
Reaction time trials correct on left1.83.410.21.92.72.31.21.81.11.2-0.81.02.3-1.0-0.80.8-0.80.83.02.0-3.1-1.63.2-1.5
Reaction time trials on left1.73.29.91.92.72.21.11.81.11.1-0.81.02.2-0.9-0.90.9-0.80.82.91.9-3.0-1.53.1-1.4
Reaction time mean1.01.52.9-1.5-1.6-1.6-1.3-1.5-1.3-1.30.9-1.1-1.60.8-0.50.4-0.50.5-1.7-1.41.51.3-1.30.7
Reaction time mean AUC0.91.52.8-1.5-1.6-1.6-1.3-1.5-1.2-1.20.9-1.1-1.51.0-0.40.4-0.40.4-1.7-1.41.51.3-1.30.5
Median of all reaction times1.01.43.0-1.4-1.7-1.6-1.2-1.4-1.2-1.10.8-1.0-1.50.9-0.30.3-0.30.3-1.7-1.31.61.1-1.40.6
Reaction time omissions0.20.30.7-0.6-0.4-0.6-0.6-0.6-0.6-0.60.8-0.6-0.60.3-0.40.4-0.40.4-0.6-0.60.40.5-0.50.3
Reaction time false alarm rate2.02.710.9-0.1-1.5-0.41.00.31.11.0-1.41.0-0.40.62.6-2.62.6-2.6-1.7-0.02.7-0.4-3.30.2
Reaction time premature initiation rate0.60.96.3-0.0-1.00.00.30.40.40.4-0.70.40.62.5-0.40.4-0.30.3-0.11.01.0-1.4-0.7-2.1
Reaction time premature initiations0.91.56.11.00.51.20.91.30.90.9-1.00.91.61.6-0.70.7-0.60.61.31.9-0.7-2.00.9-2.5
Std. dev. reaction times0.40.71.2-1.1-1.1-1.1-0.9-1.0-0.8-0.80.8-0.8-1.00.8-0.30.3-0.30.3-1.1-0.91.00.8-1.00.2
Reaction time trials completed1.73.29.91.92.72.21.11.81.11.1-0.81.02.2-0.9-0.90.9-0.80.82.91.9-3.0-1.53.1-1.4
Reaction time trials AUC1.73.210.41.82.72.21.11.71.01.0-0.70.92.1-1.1-0.90.9-0.80.82.91.8-3.1-1.43.2-1.3
Run reversals in cocaine runway, females2.42.47.2-1.9-2.5-1.9-1.0-1.5-1.0-1.11.0-1.0-1.72.20.2-0.20.2-0.2-2.3-1.42.71.0-2.6-0.0
Run reversals in cocaine runway, males0.30.31.30.40.60.60.60.50.60.4-0.60.80.5-1.20.5-0.50.5-0.50.20.4-0.5-0.5-0.20.7
Latency to leave start box in cocaine runway0.60.73.01.70.30.80.90.80.91.0-0.80.70.7-0.71.2-1.21.2-1.20.30.6-0.1-0.6-0.20.2
Latency to leave start box in cocaine runway, F1.72.04.02.00.71.41.81.61.81.6-1.71.61.4-0.61.6-1.61.6-1.70.91.4-0.2-1.5-0.3-0.4
Latency to leave start box in cocaine runway, M0.30.21.00.8-0.0-0.1-0.5-0.3-0.50.00.6-0.6-0.4-1.00.1-0.10.1-0.1-0.3-0.6-0.20.80.40.9
Std. dev. time between licks in bursts0.60.82.3-0.6-0.5-0.4-0.7-0.4-0.7-0.70.7-0.9-0.11.5-1.51.5-1.51.40.10.10.0-0.20.6-1.2
Total sessions with >9 infusions0.10.10.3-0.10.00.10.30.20.40.2-0.50.40.10.20.5-0.50.5-0.4-0.20.0-0.0-0.1-0.4-0.1
Short access day 1 total inactive lever presses0.50.75.01.01.20.50.20.10.20.1-0.3-0.00.0-2.20.6-0.60.5-0.50.3-0.3-1.10.50.71.7
Short access day 10 total inactive lever presses0.51.33.80.01.0-0.2-1.0-0.7-1.0-1.01.1-1.2-0.5-1.6-1.21.2-1.21.30.4-0.9-1.51.22.01.4
Short access day 1 total infusions0.10.10.6-0.2-0.1-0.10.2-0.00.30.1-0.50.3-0.1-0.30.6-0.60.6-0.6-0.4-0.20.30.1-0.80.5
Short access day 10 total infusions0.00.10.3-0.60.10.1-0.00.10.1-0.0-0.30.40.10.2-0.20.2-0.20.20.20.1-0.2-0.10.1-0.4
Short access total infusions0.00.10.2-0.40.30.0-0.1-0.10.0-0.1-0.20.2-0.1-0.50.1-0.10.1-0.1-0.0-0.3-0.40.40.10.3
Short access day 1 locomotion0.30.30.90.30.20.70.70.70.80.7-0.90.70.80.30.2-0.20.2-0.20.30.8-0.4-0.9-0.3-0.4
Short access day 10 total locomotion0.81.53.3-0.9-0.9-1.0-1.5-1.2-1.4-1.51.3-1.3-1.00.2-1.81.8-1.81.8-0.7-1.0-0.20.90.80.6
Short access total locomotion0.40.51.5-0.5-0.5-0.4-0.7-0.5-0.6-0.70.4-0.5-0.30.4-1.21.2-1.21.2-0.4-0.3-0.40.20.40.1
One hour access (0.3 mA shock)0.20.21.20.40.80.30.20.10.20.1-0.20.00.1-1.10.4-0.40.4-0.40.4-0.1-0.60.40.70.6
Compulsive drug intake0.30.41.7-0.3-1.1-0.6-0.4-0.3-0.4-0.40.5-0.7-0.31.3-0.60.6-0.60.5-0.40.11.1-0.3-0.3-0.7
One hour access (shock baseline)0.40.63.50.41.10.40.20.00.20.1-0.30.3-0.1-1.90.8-0.80.7-0.70.2-0.5-0.90.90.41.4
Social response proportion1.01.12.9-0.70.2-0.5-1.2-0.8-1.2-1.21.2-1.2-0.5-0.2-1.71.7-1.71.70.2-0.7-0.80.71.20.3
Social responses0.70.93.60.91.60.90.10.50.10.1-0.10.10.8-1.1-0.80.8-0.80.81.40.5-1.9-0.31.9-0.2
Social time1.31.73.0-1.4-0.9-1.4-1.6-1.5-1.6-1.61.7-1.5-1.30.3-1.51.5-1.61.6-1.0-1.30.41.2-0.10.7
Soleus weight3.08.915.83.84.03.83.33.53.23.1-3.23.03.6-2.21.4-1.41.5-1.43.83.2-3.5-2.82.7-1.4
Bone: stiffness0.30.51.20.70.10.50.90.70.90.9-0.50.70.50.41.1-1.11.1-1.10.10.60.4-0.7-0.6-0.4
Tibialis anterior weight1.44.98.92.73.02.62.52.42.52.4-2.52.52.2-2.32.1-2.12.1-2.12.11.8-2.0-1.61.0-0.0
Time to tail flick, vehicle, before self-admin0.60.61.9-0.9-1.0-1.0-0.5-0.8-0.6-0.60.5-0.6-0.90.80.3-0.30.2-0.2-1.1-0.81.40.7-1.10.2
Time to tail flick, vehicle, after self-admin0.30.51.1-0.9-0.9-0.9-0.7-0.8-0.7-0.70.8-0.6-0.80.5-0.20.2-0.20.2-0.8-0.71.10.6-0.60.2
Time to tail flick, test, before self-admin0.10.20.50.50.60.50.20.30.20.2-0.20.40.4-0.70.0-0.00.00.00.60.3-0.7-0.10.70.2
Time to tail flick, test, after self-admin1.41.48.11.12.01.30.40.70.50.5-0.50.90.8-2.80.2-0.10.1-0.01.50.2-2.40.21.91.0
Delta time to tail flick, vehicle, before/after SA0.00.00.10.10.20.20.10.20.10.1-0.20.20.2-0.3-0.10.1-0.10.10.30.3-0.2-0.30.3-0.2
Delta time to tail flick, test, before/after SA0.40.42.60.11.00.5-0.00.10.00.00.00.20.2-1.6-0.30.3-0.30.40.7-0.1-1.40.31.20.5
Tibia length0.51.53.11.30.31.21.51.51.51.6-1.31.31.40.90.9-0.91.0-1.00.81.70.2-1.8-0.2-1.5
Ambulatory time before self-admin0.60.92.0-0.5-1.2-1.3-1.0-1.1-1.0-1.00.9-1.2-1.20.6-0.30.3-0.30.3-1.4-1.11.21.0-1.00.9
Ambulatory time after self-admin1.51.84.2-1.4-1.8-1.7-1.1-1.5-1.2-1.21.0-1.3-1.70.90.0-0.0-0.00.0-2.1-1.51.91.3-2.01.2
Bone: tissue strength2.42.45.81.92.02.01.31.71.21.2-0.91.02.1-0.2-0.50.5-0.40.42.42.0-2.2-1.72.4-1.7
Total heroin consumption0.60.71.30.91.11.00.91.00.70.7-1.20.61.10.60.2-0.20.2-0.21.11.1-0.7-1.00.5-1.1
Bone: trabecular number0.30.41.2-1.1-0.7-0.7-0.7-0.6-0.7-0.70.4-0.5-0.60.9-0.70.7-0.70.7-0.5-0.50.50.4-0.5-0.3
Bone: trabecular spacing1.01.32.51.41.61.41.11.31.21.2-1.41.21.3-0.80.7-0.70.7-0.71.31.1-1.2-1.00.8-0.5
Bone: trabecular thickness1.01.23.1-1.8-1.5-1.2-1.1-1.1-1.1-1.11.1-1.0-0.91.4-1.11.1-1.11.1-1.0-0.71.00.5-0.7-0.4
Bone: trabecular tissue density0.30.50.8-0.9-0.9-0.9-0.7-0.8-0.7-0.70.6-0.6-0.90.2-0.10.1-0.20.2-0.9-0.90.70.9-0.50.5
Water consumed over 24 hours1.41.85.5-0.30.2-0.3-1.3-0.8-1.3-1.31.3-1.3-0.3-0.0-2.32.3-2.32.40.7-0.5-1.50.71.9-0.1
Number of responses in last shaping day0.91.05.5-0.9-1.4-0.9-0.1-0.6-0.0-0.1-0.1-0.0-0.90.41.1-1.11.1-1.1-1.5-0.71.80.4-2.30.7