Hub : Genes

Faap100

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XM_039087819.1 0.02 0.02 7.8e-03 0.02 0.01 0.01 0.01 2.9e-03 3.6e-02 5.3e-02 1.9e-02
2 Liver alternative TSS XM_039087820.1 0.02 0.02 6.1e-03 0.02 0.01 0.01 0.01 2.1e-03 2.6e-02 3.6e-02 1.5e-02
3 Adipose alternative TSS XM_039087819.1 0.03 0.02 2.8e-03 0.02 0.01 0.01 0.01 3.9e-03 1.6e-02 5.5e-02 2.1e-02
4 Adipose alternative TSS XM_039087820.1 0.02 0.02 4.0e-03 0.02 0.01 0.01 0.01 5.2e-03 2.3e-02 6.6e-02 3.0e-02
5 Adipose gene expression Faap100 0.04 0.03 4.6e-05 0.04 0.04 0.02 0.03 8.4e-05 8.2e-05 2.8e-03 2.6e-04
6 NAcc gene expression Faap100 0.1 0.05 1.5e-08 0.08 0.07 0.08 0.08 3.4e-09 2.8e-08 2.6e-09 2.3e-09
7 LHb gene expression Faap100 0.32 0.19 7.4e-04 0.1 0.05 0.1 0.13 2.4e-03 2.4e-02 2.3e-03 4.9e-04
8 PL gene expression Faap100 0.07 0.04 6.5e-06 0.03 0.04 0.04 0.03 1.8e-04 2.7e-05 8.0e-05 2.6e-04
9 Brain gene expression Faap100 0.23 0.1 5.6e-17 0.17 0.19 0.18 0.18 6.6e-16 4.9e-17 8.8e-17 6.6e-17
10 BLA gene expression Faap100 0.17 0.09 2.1e-06 0.03 0.1 0.08 0.08 8.6e-03 6.5e-06 4.5e-05 6.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.20.4-0.60.6-0.60.6-0.10.10.20.40.40.4
Area under the delay curve1.21.21.91.4-1.41.4-1.41.31.11.00.50.50.5
BMI with tail0.31.12.3-1.51.5-1.51.5-0.4-0.3-0.10.70.50.7
BMI without tail3.06.213.2-3.63.6-3.63.6-1.1-0.4-0.31.61.41.8
Body weight2.912.122.9-4.84.8-4.84.8-3.5-2.5-2.9-1.1-1.1-0.8
Weight adjusted by age2.73.15.0-2.22.2-2.22.2-1.7-1.7-1.6-0.9-1.0-0.9
Bone surface0.20.30.6-0.70.7-0.70.7-0.8-0.4-0.4-0.4-0.3-0.3
Bone volume0.20.30.6-0.80.8-0.80.8-0.5-0.3-0.2-0.1-0.0-0.0
Breakpoint value in progressive ratio session0.91.02.4-0.40.4-0.40.4-0.8-1.4-1.5-1.1-1.4-1.2
Number of licking bursts0.20.20.3-0.50.5-0.50.5-0.10.30.40.50.60.6
Context. condit. distance diff. score1.31.63.3-1.01.0-1.01.00.61.11.01.81.81.8
Locomotion velocity, session 11.71.94.02.0-2.02.0-2.00.6-0.00.1-0.9-0.8-1.0
Locomotion distance, session 12.93.75.11.8-1.81.8-1.82.22.22.31.71.71.7
Locomotion velocity, session 23.23.77.42.7-2.72.7-2.71.81.51.40.30.50.2
Locomotion distance, session 20.91.32.40.6-0.60.6-0.61.31.41.51.31.41.3
Locomotion velocity, session 31.11.22.81.7-1.71.7-1.70.80.40.5-0.3-0.3-0.4
Locomotion distance, session 32.22.44.32.1-2.12.1-2.11.71.31.20.60.60.4
Stereotopy head waving bouts, day 30.40.40.91.0-1.01.0-1.00.30.10.0-0.4-0.4-0.5
Stereotopy head waving duration, day 30.20.20.50.7-0.70.7-0.70.30.30.3-0.1-0.1-0.1
Locomotion velocity, session 70.50.60.90.9-0.90.9-0.91.00.80.80.60.60.5
Locomotion distance, session 73.74.77.11.7-1.71.7-1.72.72.42.62.32.32.2
Stereotopy head waving bouts, day 70.10.10.2-0.50.5-0.50.5-0.3-0.0-0.30.0-0.10.0
Stereotopy head waving duration, day 70.30.40.7-0.70.7-0.70.7-0.8-0.3-0.7-0.5-0.5-0.4
Locomotion velocity, session 81.41.72.80.6-0.60.6-0.61.41.51.61.61.71.7
Locomotion distance, session 82.63.98.7-0.60.6-0.60.61.62.22.12.92.92.9
Degree of sensitization distance0.60.60.9-0.90.9-0.90.90.10.10.50.90.91.0
Degree of sensitization stereotypy0.30.30.7-0.80.8-0.80.8-0.4-0.1-0.40.10.00.1
Conditioned locomotion2.52.96.6-2.52.5-2.62.6-1.3-0.8-0.70.40.30.5
Cocaine response after cond. corrected0.20.20.40.4-0.40.4-0.40.0-0.5-0.6-0.5-0.7-0.6
Cocaine response after cond. not corrected0.40.51.11.1-1.11.0-1.00.5-0.0-0.1-0.3-0.3-0.3
Cocaine response before conditioning0.81.01.51.0-1.01.0-1.01.01.21.10.80.90.8
Saline control response2.22.95.3-2.22.2-2.32.3-1.8-1.3-1.6-0.7-0.6-0.5
Bone: connectivity density0.30.51.2-0.10.1-0.10.10.50.90.91.01.11.0
Bone: cortical apparent density1.62.24.32.1-2.12.1-2.11.51.00.80.30.30.2
Bone: cortical area5.58.311.6-3.43.4-3.43.4-3.2-2.8-2.9-1.8-1.9-1.7
Bone: cortical porosity3.84.17.4-0.60.6-0.60.6-2.0-2.6-2.7-2.7-2.7-2.7
Bone: cortical porosity3.23.45.8-0.90.9-0.90.9-1.9-2.4-2.4-2.3-2.4-2.3
Bone: cortical thickness5.48.912.0-3.03.0-3.03.0-3.5-3.2-3.3-2.5-2.6-2.4
Bone: cortical thickness1.72.02.9-1.51.5-1.51.5-1.5-1.5-1.7-1.1-1.2-1.0
Bone: cortical tissue density1.92.55.02.2-2.22.2-2.21.71.10.90.40.30.2
Condit. Reinf. active minus inactive responses1.51.73.2-1.81.8-1.81.8-1.2-1.0-1.1-0.2-0.3-0.2
Condit. Reinf. active-inactive response ratio0.70.71.4-1.21.2-1.21.2-0.7-0.6-0.7-0.1-0.3-0.1
Condit. Reinf. active responses2.63.26.4-2.52.5-2.52.5-1.7-1.2-1.4-0.3-0.3-0.1
Condit. Reinf. inactive responses0.60.81.5-1.21.2-1.21.2-0.8-0.6-0.7-0.1-0.1-0.0
Incentive salience index mean1.21.43.0-1.71.7-1.71.7-1.1-0.7-0.8-0.1-0.1-0.0
Condit. Reinf. lever presses0.20.30.6-0.30.3-0.30.30.30.70.60.70.70.8
Condit. Reinf. active minus inactive responses0.50.61.3-1.21.2-1.11.1-0.8-0.4-0.4-0.1-0.00.0
Condit. Reinf. active-inactive response ratio1.92.03.0-1.61.6-1.51.5-1.7-1.4-1.5-1.1-1.0-1.0
Condit. Reinf. active responses0.20.20.4-0.60.6-0.60.60.00.10.30.50.50.5
Condit. Reinf. inactive responses0.70.91.50.7-0.70.7-0.71.21.01.21.00.91.0
Condit. Reinf. lever presses0.30.40.8-0.60.6-0.60.60.40.30.60.90.70.9
Condit. Reinf. lever reinforcers received0.30.40.7-0.60.6-0.60.60.30.30.50.80.70.8
Conditioned reinforcement - actives0.50.50.8-0.90.9-0.90.90.10.70.20.70.70.8
Conditioned reinforcement - inactives1.51.72.3-1.51.5-1.51.5-1.3-1.4-1.5-0.8-0.8-0.7
Conditioned locomotion0.30.30.7-0.80.8-0.80.8-0.40.2-0.40.00.10.1
Patch foraging indifference point 0 sec0.10.10.2-0.40.4-0.40.4-0.2-0.3-0.1-0.1-0.3-0.2
Patch foraging indifference point AUC0.00.00.1-0.00.00.0-0.00.20.20.40.30.30.3
Delay disc. indifference point, 0s delay0.00.00.1-0.20.2-0.20.20.10.30.10.10.10.1
Delay disc. indifference point, 16s delay2.62.64.81.0-1.01.0-1.02.02.22.11.81.81.7
Delay disc. indifference point, 2s delay0.10.20.30.6-0.60.6-0.60.40.3-0.4-0.1-0.1-0.2
Delay disc. indifference point, 24s delay3.02.95.92.4-2.42.4-2.41.71.11.00.10.1-0.1
Delay disc. indifference point, 4s delay0.30.30.80.9-0.90.9-0.90.50.4-0.1-0.0-0.1-0.1
Delay disc. indifference point, 8s delay0.60.71.51.2-1.21.2-1.20.50.10.1-0.3-0.3-0.4
Indifference point function ln k0.60.91.21.1-1.11.1-1.11.10.91.00.70.60.6
Indifference point function log k0.60.91.21.1-1.11.1-1.11.10.91.00.70.60.6
Patch foraging total patch changes 0 sec0.10.10.2-0.50.5-0.50.5-0.1-0.20.00.1-0.10.0
Patch foraging total patch changes 12 sec0.10.10.2-0.00.0-0.00.0-0.2-0.5-0.1-0.4-0.5-0.4
Patch foraging total patch changes 18 sec0.50.71.60.2-0.20.1-0.10.90.91.31.11.01.1
Patch foraging total patch changes 24 sec0.50.61.4-1.21.2-1.21.2-0.5-0.4-0.5-0.0-0.2-0.0
Patch foraging total patch changes 6 sec0.50.71.0-0.70.7-0.80.8-1.0-0.9-0.9-0.9-0.9-0.8
Patch foraging time to switch 0 sec0.30.51.21.1-1.10.9-0.90.50.40.30.00.1-0.0
Patch foraging water rate 0 sec1.62.66.4-2.52.5-2.42.4-1.0-0.7-0.50.30.10.3
Patch foraging water rate 12 sec0.60.81.5-0.90.9-0.70.70.50.70.81.21.11.2
Patch foraging water rate 18 sec0.81.11.8-1.31.3-1.31.3-0.00.50.31.11.01.2
Patch foraging water rate 24 sec1.82.54.6-2.12.1-2.12.1-0.00.40.41.51.31.6
Patch foraging water rate 6 sec0.20.30.7-0.60.6-0.50.50.20.60.20.80.80.8
Seeking ratio, delayed vs. immediate footshock0.80.91.6-1.21.2-1.31.3-1.1-0.9-1.0-0.3-0.3-0.2
Distance traveled before self-admin1.71.94.1-1.01.0-1.01.0-1.4-2.0-1.4-1.3-1.5-1.4
Distance traveled after self-admin0.30.40.7-0.80.8-0.80.8-0.1-0.20.30.50.40.5
Extensor digitorum longus weight0.41.74.0-0.60.6-0.60.61.01.31.32.01.92.0
Bone: elastic displacement1.51.72.4-1.21.2-1.21.2-1.5-1.5-1.3-1.1-1.3-1.1
Bone: elastic work8.210.615.4-2.92.9-2.92.9-3.8-3.9-3.6-3.1-3.3-3.0
Bone: endosteal estimation0.30.71.6-0.20.2-0.20.20.71.00.91.31.21.3
Bone: endosteal perimeter0.61.11.8-1.41.4-1.41.4-1.2-0.9-1.0-0.6-0.5-0.5
Epididymis fat weight0.81.84.1-2.02.0-2.02.0-0.9-0.3-0.60.40.30.5
Delta time in closed arm before/after self-admin0.10.10.5-0.10.1-0.10.1-0.10.70.40.20.50.3
Delta time in open arm before/after self-admin0.20.20.4-0.50.5-0.50.50.40.20.40.60.40.5
Diff in mean of infusions in LGA sessions0.10.10.10.3-0.30.3-0.30.20.1-0.2-0.1-0.2-0.2
Delay discount exponential model param1.61.63.0-1.71.7-1.71.7-1.4-1.1-0.9-0.3-0.4-0.3
Extinction: sum of active levers before priming0.70.71.41.2-1.21.2-1.20.80.30.5-0.1-0.2-0.2
Active lever presses in extinction session 60.60.61.40.2-0.20.2-0.2-0.2-0.8-1.2-1.0-1.2-1.1
Bone: final force4.57.311.5-3.43.4-3.43.4-2.9-2.5-2.6-1.4-1.5-1.3
Bone: final moment5.48.813.0-3.63.6-3.63.6-3.2-2.9-2.9-1.8-1.9-1.6
Food consumed during 24 hour testing period0.30.40.8-0.90.9-0.90.9-0.5-0.5-0.4-0.1-0.2-0.0
Glucose2.94.36.92.6-2.62.6-2.60.4-1.1-1.0-2.0-2.1-2.2
Heart weight0.30.50.9-0.90.9-0.90.9-0.6-0.7-0.4-0.2-0.3-0.2
Delay discount hyperbolic model param1.51.52.9-1.71.7-1.71.7-1.4-1.1-0.8-0.3-0.4-0.3
Intermittent access intake day 1-15 change0.50.51.3-0.50.5-0.50.5-0.9-1.1-0.4-0.7-0.6-0.6
Intermittent access intake escalation0.30.30.6-0.60.6-0.60.6-0.7-0.8-0.4-0.4-0.3-0.3
Intermittent access intake escalation 22.22.24.1-1.01.0-1.01.0-1.7-1.8-2.0-1.6-1.6-1.5
Intermitt. access day 1 inactive lever presses1.51.62.1-1.41.4-1.41.4-1.2-1.4-1.1-0.9-1.0-0.9
Intermitt. access day 15 inactive lever presses1.21.33.0-1.71.7-1.71.7-0.7-0.3-0.40.20.30.4
Intermitt. access escalation Index1.41.22.5-1.61.6-1.51.5-0.30.50.40.80.80.9
Intermittent access day 1 total infusions0.10.10.2-0.40.4-0.40.4-0.4-0.4-0.30.00.00.1
Intermittent access day 15 total infusions0.30.40.8-0.80.8-0.90.9-0.6-0.5-0.3-0.00.00.1
Intermittent access terminal intake (last 3 days)0.80.91.5-1.21.2-1.21.2-1.1-1.0-0.9-0.4-0.4-0.4
Intermittent access total infusions0.30.30.6-0.80.8-0.80.8-0.6-0.5-0.4-0.00.00.1
Intermittent access day 1 locomotion0.40.40.8-0.90.9-0.90.9-0.40.1-0.30.20.30.3
Intermittent access day 15 total locomotion0.40.50.9-0.70.7-0.60.6-0.9-0.6-0.8-0.6-0.6-0.5
Intermittent access total locomotion0.40.50.9-0.90.9-0.90.9-0.8-0.4-0.7-0.3-0.2-0.2
Intermittent access standard deviation1.01.11.90.9-0.90.9-0.9-0.4-1.2-0.9-1.3-1.4-1.4
Left kidney weight0.30.71.4-0.40.4-0.40.4-1.1-0.8-1.2-1.2-1.0-1.1
Right kidney weight0.00.10.2-0.20.2-0.20.2-0.50.1-0.3-0.4-0.3-0.3
Cocaine induced anxiety5.96.812.4-2.12.1-2.12.1-2.8-3.5-3.0-2.5-2.8-2.6
Post-drug Anxiety1.21.43.1-0.50.5-0.50.5-1.0-1.8-1.7-1.3-1.5-1.4
Baseline Anxiety6.46.89.12.9-2.92.9-2.92.93.02.41.82.01.8
Tail length3.510.723.0-4.84.8-4.74.7-3.0-1.7-1.9-0.1-0.10.2
Length with tail2.59.213.5-3.73.7-3.63.6-3.6-2.5-3.0-2.0-1.9-1.7
Length without tail1.22.66.10.3-0.30.3-0.3-1.5-1.4-1.9-2.5-2.4-2.4
Times rat made contact with spout2.12.54.0-1.01.0-1.01.0-1.8-2.0-1.8-1.8-1.9-1.8
Lifetime Intake0.10.10.1-0.30.3-0.30.3-0.3-0.2-0.20.00.10.1
Liver weight, left0.50.71.60.5-0.50.5-0.5-0.5-0.9-0.9-1.2-1.2-1.3
Liver weight, right1.93.14.8-2.22.2-2.12.1-2.2-1.4-1.6-1.2-1.0-1.0
Locomotor activity0.30.51.01.0-1.01.0-1.00.80.70.40.20.20.1
Locomotor testing distance0.50.81.90.6-0.60.7-0.71.31.40.70.90.80.8
Locomotor testing rearing0.30.51.1-0.20.2-0.10.10.91.00.80.90.80.9
Locomotion in novel chamber0.40.51.30.0-0.00.1-0.10.81.01.10.90.90.9
Locomotion in novel chamber post-restriction1.01.22.3-1.21.2-1.21.2-1.5-1.5-0.9-0.7-0.7-0.6
Fecal boli incidents, locomotor time 10.50.60.80.8-0.80.8-0.80.90.90.70.60.60.6
Change in fecal boli incidents, locomotor task2.01.93.82.0-2.02.0-2.00.5-0.3-0.1-1.0-1.0-1.1
Time >=10cm from walls, locomotor time 10.60.61.5-0.20.2-0.20.20.20.71.01.21.21.2
Bouts of movement, locomotor time 11.31.52.91.7-1.71.7-1.71.20.80.80.40.40.3
Total resting periods, locomotor time 11.61.83.92.0-2.02.0-2.01.10.60.60.10.1-0.0
Rest time, locomotor task time 10.30.40.60.6-0.60.6-0.6-0.2-0.4-0.6-0.8-0.7-0.8
Distance moved, locomotor task time 10.40.40.9-0.90.9-0.90.9-0.3-0.10.40.40.40.4
Vertical activity count, locomotor time 11.11.12.0-1.41.4-1.41.4-0.20.30.50.90.91.0
Time >=10cm from walls, locomotor time 20.00.00.10.2-0.20.2-0.2-0.20.40.10.10.30.2
Bouts of movement, locomotor time 21.21.31.71.2-1.21.2-1.21.31.21.10.80.90.8
Total resting periods, locomotor time 21.01.11.80.9-0.90.9-0.91.21.31.21.01.11.0
Rest time, locomotor task time 20.00.10.10.4-0.40.4-0.40.00.10.1-0.10.0-0.0
Distance moved, locomotor task time 20.00.00.1-0.30.3-0.30.3-0.10.20.20.10.20.1
Vertical activity count, locomotor time 20.60.61.2-0.50.5-0.50.50.40.90.71.01.11.1
Light reinforcement 11.01.83.7-1.91.9-1.71.7-0.30.30.21.21.11.2
Light reinforcement 21.52.14.9-2.22.2-2.02.0-1.2-0.5-0.90.20.20.3
Bone: marrow area0.30.71.6-0.20.2-0.20.20.71.00.91.31.21.3
Bone: maximum diameter1.32.43.8-1.91.9-1.91.9-1.8-1.2-1.4-0.9-0.8-0.8
Bone: maximum force4.27.212.0-3.53.5-3.53.5-2.9-2.3-2.4-1.2-1.3-1.1
Bone: maximum moment5.08.613.4-3.73.7-3.73.7-3.2-2.7-2.7-1.5-1.6-1.4
Mean time between licks in bursts1.31.82.61.6-1.61.6-1.61.51.41.30.80.90.7
Mean num. licks in bursts0.80.92.0-0.30.3-0.30.3-0.8-1.3-1.2-1.3-1.4-1.3
Cd content in liver1.81.93.01.6-1.61.6-1.61.71.31.31.11.01.0
Co content in liver0.10.10.20.2-0.20.2-0.20.50.40.20.30.20.3
Cu content in liver1.41.63.2-0.40.4-0.40.4-1.3-1.6-1.4-1.8-1.8-1.8
Fe content in liver0.81.01.31.1-1.11.1-1.11.21.01.00.70.70.7
K content in liver1.41.43.1-1.81.8-1.81.8-1.0-0.2-0.20.30.30.4
Mg content in liver1.21.22.6-0.60.6-0.60.60.51.21.21.51.61.6
Mn content in liver0.30.30.5-0.60.6-0.60.6-0.7-0.5-0.4-0.5-0.4-0.4
Na content in liver0.00.00.1-0.20.2-0.20.2-0.3-0.1-0.1-0.2-0.2-0.2
Rb content in liver0.60.71.3-1.11.1-1.11.1-0.20.10.30.70.70.8
Se content in liver0.20.20.4-0.60.6-0.60.6-0.4-0.2-0.30.10.10.1
Sr content in liver1.41.32.80.6-0.60.6-0.6-0.7-1.2-1.2-1.6-1.6-1.7
Zn content in liver0.10.10.30.1-0.10.1-0.1-0.5-0.2-0.1-0.6-0.4-0.5
Bone: minimum diameter3.05.57.8-2.82.8-2.82.8-2.6-2.2-2.5-1.5-1.6-1.4
Time in familiar zone, hab. session 10.10.10.30.3-0.30.3-0.3-0.0-0.5-0.4-0.4-0.4-0.4
Time in novel zone, hab. session 10.10.10.2-0.20.2-0.20.20.10.40.40.40.40.4
Total zone transitions, hab. session 10.40.61.10.6-0.60.6-0.61.10.80.80.90.80.8
Total locomotion distance, hab. session 10.30.40.9-0.50.5-0.50.50.50.40.41.00.80.9
Locomotion velocity, hab. session 10.30.40.9-0.60.6-0.60.60.40.40.41.00.80.9
Time in familiar zone, hab. session 20.30.30.70.4-0.40.4-0.40.80.50.50.70.60.6
Time in novel zone, hab. session 20.00.00.10.2-0.20.2-0.20.00.30.3-0.00.10.0
Total zone transitions, hab. session 21.72.24.30.3-0.30.3-0.31.51.81.82.02.02.1
Total locomotion distance, hab. session 21.31.83.8-0.90.9-0.90.90.71.31.21.91.91.9
Locomotion velocity, hab. session 21.21.63.1-1.21.2-1.21.20.41.01.01.71.71.8
Novel to familiar place preference ratio3.23.35.0-1.61.6-1.61.6-2.0-2.2-2.1-1.7-1.9-1.7
Novelty place preference3.23.35.1-1.51.5-1.51.5-2.0-2.3-2.1-1.8-1.9-1.7
Time in novel zone, NPP test2.42.53.8-1.41.4-1.41.4-1.7-2.0-1.8-1.5-1.6-1.4
Total zone transitions, NPP test2.43.46.40.4-0.40.4-0.41.92.32.32.52.52.5
Total locomotion distance, NPP test2.12.96.5-0.50.5-0.50.51.42.01.82.52.52.5
Locomotion velocity, NPP test1.31.94.2-0.70.7-0.70.71.01.51.42.01.92.0
Intraocular pressure0.20.30.6-0.80.8-0.80.8-0.3-0.2-0.40.20.20.3
Delta distance traveled before/after self-admin1.21.32.40.2-0.20.2-0.21.31.51.41.61.51.6
Delta ambulatory time before/after self-admin1.71.93.60.7-0.70.7-0.71.61.91.71.61.61.6
Parametrial fat weight1.32.54.3-2.02.0-2.12.1-1.7-1.5-1.2-0.7-0.7-0.6
Pavlov. Cond. lever latency2.32.95.20.9-0.90.8-0.82.21.82.02.32.22.2
Pavlov. Cond. magazine entry latency3.44.46.3-1.61.6-1.51.5-2.4-2.5-2.5-2.3-2.4-2.3
Pavlov. Cond. change in total contacts1.61.73.5-0.30.3-0.30.3-1.2-1.5-1.7-1.7-1.9-1.8
Pavlov. Cond. index score3.74.77.1-2.02.0-1.91.9-2.7-2.3-2.4-2.1-2.1-2.0
Pavlov. Cond. latency score3.44.46.9-1.71.7-1.61.6-2.6-2.3-2.4-2.3-2.3-2.2
Pavlov. Cond. lever contacts1.31.52.6-0.90.9-0.90.9-1.6-1.2-1.3-1.4-1.4-1.4
Pavlov. Cond. magazine entry number3.94.97.51.3-1.31.2-1.22.52.72.72.72.72.7
Pavlov. Cond. intertrial magazine entries0.40.51.1-0.70.7-0.70.70.30.40.51.01.01.1
Pavlov. Cond. lever-magazine prob. diff.3.94.87.1-2.02.0-2.02.0-2.7-2.4-2.5-2.1-2.2-2.1
Pavlov. Cond. response bias3.54.25.9-1.41.4-1.31.3-2.4-2.4-2.4-2.4-2.4-2.4
Pavlov. Cond. lever latency0.71.01.41.2-1.21.1-1.1-0.2-0.4-0.8-1.1-1.0-1.2
Pavlov. Cond. magazine entry latency2.52.94.61.3-1.31.2-1.22.11.92.11.91.81.8
Pavlov. Cond. change in total contacts0.81.12.40.2-0.20.1-0.11.31.11.41.51.31.5
Pavlov. Cond. index score0.81.02.10.1-0.10.1-0.11.21.01.31.51.21.4
Pavlov. Cond. latency score0.91.12.4-0.00.0-0.10.11.21.11.31.51.31.5
Pavlov. Cond. lever contacts0.91.31.8-1.31.3-1.31.30.20.40.91.31.11.3
Pavlov. Cond. magazine entry number2.02.54.0-0.90.9-0.90.9-2.0-1.8-2.0-1.9-1.7-1.8
Pavlov. Cond. intertrial magazine entries1.11.53.0-1.71.7-1.61.6-1.3-0.8-0.9-0.4-0.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.91.12.40.2-0.20.2-0.21.41.11.41.51.31.4
Pavlov. Cond. response bias0.71.02.1-0.50.5-0.50.50.80.81.31.41.31.4
Time in closed arm before self-admin0.60.71.01.0-1.01.0-1.0-0.0-1.0-0.5-0.7-0.8-0.9
Time in closed arm after self-admin1.61.62.41.5-1.51.5-1.5-0.3-0.9-0.6-1.4-1.2-1.4
Time in open arm before self-admin0.20.21.5-0.20.2-0.20.20.11.20.20.40.60.5
Time in open arm after self-admin0.50.51.3-0.20.2-0.20.20.71.10.81.00.91.0
Bone: periosteal estimation1.42.95.6-2.42.4-2.42.4-1.7-1.2-1.4-0.5-0.5-0.4
Bone: periosteal perimeter3.76.29.1-2.42.4-2.42.4-3.0-2.7-2.8-2.3-2.3-2.2
Bone: post-yield work0.40.51.1-0.10.1-0.10.10.60.80.91.01.01.0
Progressive ratio test 1 active lever presses0.60.61.2-1.11.1-1.11.1-0.8-0.6-0.7-0.00.00.1
Progressive ratio test 1 breakpoint0.70.81.4-1.21.2-1.21.2-0.9-0.8-0.7-0.0-0.10.0
Progressive ratio test 1 inactive lever presses1.82.04.6-2.12.1-2.12.1-1.2-0.8-0.50.0-0.10.1
Progressive ratio test 2 active lever presses0.30.30.5-0.60.6-0.60.6-0.7-0.6-0.6-0.4-0.3-0.3
Progressive ratio test 2 breakpoint0.30.30.7-0.90.9-0.80.8-0.6-0.4-0.4-0.00.00.1
Progressive ratio test 2 inactive lever presses0.50.50.9-0.70.7-0.70.7-0.8-0.8-1.0-0.6-0.6-0.5
Incentive Sensitization - Responses0.10.10.3-0.20.2-0.10.1-0.4-0.60.1-0.3-0.2-0.2
Incentive Sensitization - Breakpoint0.10.10.3-0.20.2-0.10.1-0.4-0.60.1-0.3-0.3-0.3
Sum of active levers in priming session hrs 5-60.90.82.0-0.50.5-0.50.5-0.6-1.4-1.4-0.9-1.2-1.0
Progressive ratio0.20.20.40.5-0.50.6-0.60.60.40.10.10.10.1
Food seeking constrained by brief footshock0.20.20.50.4-0.40.5-0.5-0.0-0.4-0.5-0.6-0.7-0.6
Seeking ratio, punishment vs. effort0.10.10.2-0.30.3-0.40.4-0.2-0.20.10.10.10.1
Retroperitoneal fat weight3.411.222.2-4.74.7-4.74.7-3.2-2.5-2.2-0.7-1.0-0.6
Reaction time number correct3.85.512.0-0.80.8-0.70.71.92.72.73.43.33.5
Reaction time mean minus median0.30.30.80.4-0.40.3-0.3-0.4-0.5-0.3-0.9-0.8-0.9
Reaction time mean minus median AUC0.10.10.2-0.30.3-0.30.3-0.5-0.10.0-0.4-0.3-0.4
Reaction time num false alarms0.30.40.90.9-0.90.8-0.80.60.20.40.20.20.1
Reaction time num false alarms AUC0.60.81.61.3-1.31.1-1.11.00.70.70.50.50.4
Reaction time trials correct on left3.85.512.0-0.80.8-0.70.71.92.72.73.43.33.5
Reaction time trials on left4.05.712.4-0.90.9-0.70.71.92.82.73.53.43.5
Reaction time mean0.20.20.5-0.70.7-0.70.7-0.3-0.10.20.20.20.2
Reaction time mean AUC0.30.40.5-0.70.7-0.70.70.00.30.50.70.60.7
Median of all reaction times0.20.30.5-0.70.7-0.70.7-0.00.10.40.50.50.5
Reaction time omissions0.30.40.6-0.80.8-0.80.80.00.40.40.50.50.5
Reaction time false alarm rate1.01.42.41.5-1.51.3-1.3-0.1-0.7-0.7-1.2-1.2-1.3
Reaction time premature initiation rate0.91.22.31.5-1.51.5-1.51.20.80.70.30.30.2
Reaction time premature initiations2.12.94.60.9-0.91.0-1.02.12.22.02.12.02.0
Std. dev. reaction times0.30.40.90.7-0.70.7-0.70.60.60.90.40.40.4
Reaction time trials completed4.05.712.4-0.90.9-0.70.71.92.82.73.53.43.5
Reaction time trials AUC3.95.612.2-0.90.9-0.80.81.92.72.73.53.33.5
Run reversals in cocaine runway, females1.81.73.20.9-0.90.9-0.91.51.51.81.51.41.4
Run reversals in cocaine runway, males2.32.24.0-0.90.9-0.90.9-1.7-1.9-2.0-1.7-1.7-1.7
Latency to leave start box in cocaine runway0.40.50.90.6-0.60.6-0.60.70.71.00.60.70.6
Latency to leave start box in cocaine runway, F0.91.02.00.3-0.30.2-0.21.01.41.31.31.41.3
Latency to leave start box in cocaine runway, M0.10.10.50.2-0.20.2-0.2-0.3-0.7-0.1-0.4-0.4-0.4
Std. dev. time between licks in bursts2.12.55.3-1.01.0-1.01.00.81.51.52.22.22.3
Total sessions with >9 infusions0.20.20.30.6-0.60.6-0.60.40.50.50.30.50.4
Short access day 1 total inactive lever presses0.50.51.5-0.30.3-0.40.40.31.20.30.91.11.0
Short access day 10 total inactive lever presses2.62.94.3-2.12.1-2.12.1-1.9-1.8-1.4-1.0-1.2-0.9
Short access day 1 total infusions0.90.91.71.3-1.31.3-1.31.01.00.60.40.50.3
Short access day 10 total infusions0.50.51.0-0.70.7-0.70.7-0.9-1.0-0.9-0.5-0.6-0.5
Short access total infusions0.00.00.00.2-0.20.2-0.2-0.0-0.1-0.00.00.10.0
Short access day 1 locomotion0.20.20.30.5-0.50.5-0.5-0.00.0-0.2-0.5-0.4-0.5
Short access day 10 total locomotion0.50.61.20.4-0.40.6-0.6-0.5-0.6-1.0-1.1-1.0-1.1
Short access total locomotion0.30.40.60.8-0.80.8-0.8-0.1-0.2-0.4-0.6-0.5-0.6
One hour access (0.3 mA shock)0.70.81.6-1.21.2-1.31.3-0.8-0.8-0.40.10.00.2
Compulsive drug intake0.30.30.7-0.80.8-0.80.8-0.2-0.5-0.10.30.10.2
One hour access (shock baseline)0.20.20.4-0.60.6-0.60.6-0.30.3-0.00.30.40.4
Social response proportion0.40.50.90.3-0.30.3-0.30.91.00.90.80.80.8
Social responses0.10.20.40.0-0.0-0.00.00.40.60.30.60.60.6
Social time0.20.20.40.0-0.00.0-0.00.60.60.70.70.60.6
Soleus weight0.92.85.5-2.42.4-2.32.3-1.7-1.1-1.1-0.4-0.4-0.2
Bone: stiffness0.50.81.6-1.31.3-1.31.3-0.8-0.5-0.7-0.1-0.1-0.0
Tibialis anterior weight0.10.41.0-0.40.4-0.30.30.30.70.70.91.00.9
Time to tail flick, vehicle, before self-admin0.00.00.1-0.20.2-0.20.2-0.10.20.30.20.20.2
Time to tail flick, vehicle, after self-admin1.51.62.81.7-1.71.7-1.71.31.20.80.60.80.6
Time to tail flick, test, before self-admin0.20.20.70.0-0.0-0.00.0-0.5-0.5-0.8-0.7-0.6-0.6
Time to tail flick, test, after self-admin0.10.10.20.3-0.30.3-0.30.10.1-0.4-0.1-0.0-0.1
Delta time to tail flick, vehicle, before/after SA0.40.40.80.2-0.20.2-0.20.80.90.50.80.90.8
Delta time to tail flick, test, before/after SA0.20.20.40.7-0.70.7-0.70.30.10.1-0.2-0.2-0.3
Tibia length8.524.034.6-5.25.2-5.25.2-5.9-5.2-5.0-4.0-4.0-3.7
Ambulatory time before self-admin2.52.64.4-1.51.5-1.51.5-1.8-2.1-1.7-1.3-1.5-1.4
Ambulatory time after self-admin0.20.20.5-0.70.7-0.70.7-0.2-0.3-0.10.30.10.3
Bone: tissue strength0.90.91.9-1.41.4-1.41.4-0.6-0.2-0.20.40.30.5
Total heroin consumption0.91.03.3-0.30.3-0.30.3-0.6-1.3-1.8-1.1-1.3-1.3
Bone: trabecular number0.00.00.0-0.10.1-0.10.1-0.00.10.00.10.20.1
Bone: trabecular spacing1.62.14.8-0.70.7-0.70.71.11.41.32.22.02.2
Bone: trabecular thickness1.82.24.2-0.40.4-0.40.4-1.6-1.9-1.7-2.0-2.0-2.1
Bone: trabecular tissue density0.60.91.51.2-1.21.2-1.21.00.80.80.40.40.3
Water consumed over 24 hours0.40.51.20.2-0.20.2-0.2-0.6-0.7-0.7-1.1-1.1-1.1
Number of responses in last shaping day1.41.43.3-1.81.8-1.81.8-0.9-0.4-0.5-0.1-0.00.0