Hub : Genes

F2rl1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression F2rl1 0.54 0.1 0.0e+00 0.3 0.36 0.35 0.34 1.0e-33 6.0e-41 1.0e-40 8.1e-39
2 PL gene expression F2rl1 0.1 0.05 1.7e-07 0.04 0.05 0.05 0.05 8.3e-05 1.9e-06 1.4e-06 1.4e-06
3 NAcc gene expression F2rl1 0.19 0.08 0.0e+00 0.15 0.2 0.2 0.2 4.9e-22 1.6e-29 5.4e-29 6.2e-30
4 pVTA gene expression F2rl1 0.28 0.15 8.4e-13 0.15 0.17 0.15 0.16 2.2e-12 1.2e-13 4.2e-12 1.7e-12
5 RMTg gene expression F2rl1 0.15 0.08 4.6e-04 0.17 0.17 0.13 0.16 3.5e-05 3.7e-05 2.2e-04 4.5e-05
6 OFC gene expression F2rl1 0.56 0.16 1.3e-08 0.3 0.25 0.27 0.28 6.1e-08 1.2e-06 5.0e-07 2.2e-07
7 IC gene expression F2rl1 0.25 0.11 4.2e-07 0.08 0.12 0.09 0.12 2.1e-04 1.5e-05 1.7e-04 1.2e-05
8 Brain gene expression F2rl1 0.14 0.08 2.2e-08 0.08 0.09 0.09 0.09 5.4e-08 1.6e-08 1.6e-08 6.0e-09
9 BLA gene expression F2rl1 0.12 0.07 6.3e-05 0.03 0.06 0.04 0.04 8.0e-03 2.6e-04 4.8e-03 2.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.31.71.3-0.0-0.10.60.40.40.2-0.2-0.2
Area under the delay curve2.53.95.9-0.0-2.42.42.0-2.1-2.11.92.21.5
BMI with tail0.62.16.1-2.5-1.00.7-0.2-2.1-2.10.31.50.8
BMI without tail0.52.510.2-3.21.1-1.4-2.0-0.2-0.2-1.8-0.7-1.2
Body weight0.52.211.5-3.40.7-0.8-1.7-1.2-1.2-1.20.5-0.4
Weight adjusted by age0.00.10.30.10.10.50.6-0.2-0.20.30.50.2
Bone surface0.30.70.80.8-0.80.70.9-0.9-0.90.80.90.7
Bone volume0.40.83.41.9-0.80.51.1-0.0-0.10.90.40.6
Breakpoint value in progressive ratio session0.51.02.00.8-0.71.31.4-0.7-0.71.20.80.9
Number of licking bursts0.10.21.0-1.0-0.1-0.2-0.60.00.0-0.3-0.20.0
Context. condit. distance diff. score0.30.31.01.00.3-0.10.50.70.7-0.0-0.4-0.6
Locomotion velocity, session 11.01.21.90.41.2-1.0-0.41.31.4-0.8-1.3-1.4
Locomotion distance, session 11.72.24.60.62.1-1.3-0.51.91.9-1.0-1.7-1.4
Locomotion velocity, session 21.11.32.70.41.6-0.9-0.11.41.4-0.7-1.3-1.4
Locomotion distance, session 21.11.63.40.71.3-1.1-0.31.81.8-0.6-1.6-1.2
Locomotion velocity, session 30.40.51.71.30.10.61.30.30.30.70.0-0.1
Locomotion distance, session 30.91.02.31.0-0.81.21.5-0.7-0.71.20.90.8
Stereotopy head waving bouts, day 31.11.32.70.30.8-1.0-0.81.61.6-0.9-1.4-1.1
Stereotopy head waving duration, day 30.20.20.4-0.40.5-0.3-0.40.50.5-0.5-0.5-0.6
Locomotion velocity, session 71.31.53.41.6-1.21.31.8-0.3-0.31.50.90.9
Locomotion distance, session 70.10.20.30.2-0.30.50.5-0.3-0.30.50.50.5
Stereotopy head waving bouts, day 70.60.71.90.00.7-0.5-0.21.11.1-0.7-1.1-1.4
Stereotopy head waving duration, day 70.30.31.2-0.10.4-0.20.10.70.7-0.4-0.7-1.1
Locomotion velocity, session 84.45.39.61.02.5-2.2-1.13.13.1-1.6-2.8-2.3
Locomotion distance, session 81.01.52.70.91.2-0.9-0.01.61.6-0.6-1.4-1.6
Degree of sensitization distance0.60.61.3-0.70.5-0.9-1.10.70.7-0.9-0.8-0.7
Degree of sensitization stereotypy0.10.10.30.10.00.30.50.20.20.1-0.2-0.5
Conditioned locomotion0.20.20.3-0.5-0.60.50.3-0.5-0.50.30.40.5
Cocaine response after cond. corrected0.10.20.40.3-0.10.50.6-0.4-0.40.50.50.5
Cocaine response after cond. not corrected0.00.00.10.10.3-0.00.2-0.1-0.1-0.20.0-0.3
Cocaine response before conditioning0.40.51.2-0.10.5-0.8-0.60.60.6-1.0-0.7-1.1
Saline control response0.71.03.3-1.81.3-0.8-1.00.10.1-1.2-0.5-0.9
Bone: connectivity density0.10.10.50.50.7-0.20.30.10.1-0.2-0.1-0.4
Bone: cortical apparent density0.71.14.62.1-1.10.71.20.30.31.10.11.0
Bone: cortical area0.61.11.50.9-1.11.21.1-0.7-0.71.21.01.2
Bone: cortical porosity0.30.30.6-0.10.10.70.6-0.5-0.50.60.60.7
Bone: cortical porosity0.30.40.70.00.10.80.7-0.5-0.50.70.60.8
Bone: cortical thickness0.71.12.11.5-0.81.21.5-0.3-0.31.30.81.1
Bone: cortical thickness0.50.61.0-0.4-0.70.60.4-1.0-1.00.60.90.8
Bone: cortical tissue density0.71.14.72.2-1.20.71.10.30.31.10.11.0
Condit. Reinf. active minus inactive responses0.70.81.4-0.51.2-1.1-1.00.80.8-1.0-1.0-0.7
Condit. Reinf. active-inactive response ratio1.31.32.0-0.81.0-1.4-1.40.91.0-1.4-1.2-1.1
Condit. Reinf. active responses0.50.61.6-0.41.3-0.8-0.70.70.7-0.7-0.8-0.5
Condit. Reinf. inactive responses0.10.10.40.30.60.10.40.20.20.2-0.00.0
Incentive salience index mean0.30.41.1-0.71.0-0.7-0.60.30.3-0.8-0.5-0.6
Condit. Reinf. lever presses0.20.20.6-0.10.20.50.8-0.6-0.60.40.50.1
Condit. Reinf. active minus inactive responses0.40.60.90.3-0.70.90.9-0.6-0.60.90.70.8
Condit. Reinf. active-inactive response ratio0.10.10.4-0.2-0.60.30.2-0.3-0.30.20.30.1
Condit. Reinf. active responses0.60.91.80.7-0.61.11.3-0.6-0.61.10.90.9
Condit. Reinf. inactive responses0.10.20.3-0.10.30.50.6-0.5-0.50.30.50.2
Condit. Reinf. lever presses1.11.62.21.2-1.01.41.4-0.9-0.91.51.31.5
Condit. Reinf. lever reinforcers received1.01.52.30.8-1.01.41.5-1.0-1.01.41.21.3
Conditioned reinforcement - actives0.83.44.5-1.12.1-2.1-2.11.41.4-2.1-1.8-2.1
Conditioned reinforcement - inactives0.10.20.5-0.50.7-0.5-0.50.60.6-0.3-0.2-0.3
Conditioned locomotion2.53.77.00.51.7-2.0-1.42.62.6-1.5-2.2-1.9
Patch foraging indifference point 0 sec0.20.51.1-0.9-0.6-0.0-0.8-1.0-1.0-0.10.60.6
Patch foraging indifference point AUC0.40.92.0-0.6-0.81.00.7-1.4-1.40.61.00.6
Delay disc. indifference point, 0s delay4.24.77.60.9-2.32.82.3-1.7-1.72.52.32.3
Delay disc. indifference point, 16s delay0.81.11.8-0.2-1.31.20.9-1.3-1.30.91.10.6
Delay disc. indifference point, 2s delay4.44.97.70.8-2.82.82.5-1.8-1.82.32.42.0
Delay disc. indifference point, 24s delay2.94.66.6-0.3-2.22.52.2-2.5-2.51.82.61.6
Delay disc. indifference point, 4s delay2.42.64.10.5-2.02.01.8-1.4-1.41.71.81.2
Delay disc. indifference point, 8s delay1.01.72.4-0.6-1.61.51.3-1.5-1.51.21.50.7
Indifference point function ln k0.31.01.30.20.8-1.1-0.91.11.1-1.0-1.1-1.0
Indifference point function log k0.31.01.30.20.8-1.1-0.91.11.1-1.0-1.1-1.0
Patch foraging total patch changes 0 sec0.20.51.0-0.9-0.80.0-0.7-1.0-1.0-0.10.60.6
Patch foraging total patch changes 12 sec1.01.42.8-0.8-1.00.80.1-1.7-1.70.71.41.4
Patch foraging total patch changes 18 sec1.22.85.4-0.5-1.51.60.8-2.3-2.31.21.91.9
Patch foraging total patch changes 24 sec0.72.45.7-1.9-1.10.9-0.2-2.4-2.40.41.71.1
Patch foraging total patch changes 6 sec1.11.83.7-0.3-1.41.10.6-1.9-1.90.91.61.4
Patch foraging time to switch 0 sec0.62.33.30.6-1.51.51.5-1.5-1.51.81.71.8
Patch foraging water rate 0 sec0.31.21.6-0.91.0-1.2-1.30.90.9-1.3-1.1-1.2
Patch foraging water rate 12 sec0.20.81.6-0.10.6-0.9-1.01.31.3-0.8-1.1-0.6
Patch foraging water rate 18 sec0.71.53.3-1.80.7-1.2-1.70.50.5-1.6-0.9-1.2
Patch foraging water rate 24 sec0.40.62.1-1.50.5-0.6-0.90.20.2-1.0-0.5-0.9
Patch foraging water rate 6 sec0.40.61.10.10.4-0.6-0.51.01.0-0.8-1.0-1.1
Seeking ratio, delayed vs. immediate footshock0.91.32.1-0.71.5-1.0-1.21.01.0-1.4-1.2-1.3
Distance traveled before self-admin0.51.11.80.0-1.31.20.8-1.2-1.20.81.20.9
Distance traveled after self-admin0.30.51.8-1.3-0.00.7-0.0-1.0-1.0-0.00.80.1
Extensor digitorum longus weight0.10.31.11.0-0.70.30.5-0.1-0.10.50.30.5
Bone: elastic displacement1.21.52.91.7-1.31.41.5-0.4-0.41.50.91.3
Bone: elastic work0.40.51.51.2-0.80.81.00.00.00.90.30.5
Bone: endosteal estimation0.10.30.6-0.5-0.80.1-0.5-0.7-0.70.10.50.5
Bone: endosteal perimeter0.10.20.4-0.2-0.50.3-0.2-0.6-0.70.10.50.4
Epididymis fat weight1.05.112.9-3.61.7-2.3-2.90.60.6-2.7-1.6-2.4
Delta time in closed arm before/after self-admin1.31.21.81.0-1.11.21.1-0.8-0.81.31.11.4
Delta time in open arm before/after self-admin0.10.10.30.10.20.10.6-0.3-0.30.20.30.1
Diff in mean of infusions in LGA sessions0.20.41.41.2-0.20.81.20.10.10.6-0.00.0
Delay discount exponential model param2.63.65.60.02.4-2.3-2.02.02.0-1.8-2.1-1.4
Extinction: sum of active levers before priming0.10.20.4-0.1-0.30.60.3-0.5-0.50.60.40.6
Active lever presses in extinction session 61.61.72.40.4-1.11.51.4-1.4-1.41.31.51.1
Bone: final force1.72.73.51.2-1.81.81.7-1.5-1.41.91.81.6
Bone: final moment1.72.73.51.1-1.71.81.7-1.5-1.51.91.81.7
Food consumed during 24 hour testing period1.02.14.1-0.6-1.41.20.5-2.0-2.01.01.81.6
Glucose0.61.04.22.1-0.0-0.30.31.41.40.2-0.8-0.1
Heart weight0.81.34.6-2.11.3-0.9-1.1-0.2-0.2-1.4-0.5-1.1
Delay discount hyperbolic model param2.53.35.20.02.3-2.2-1.91.91.9-1.7-2.0-1.3
Intermittent access intake day 1-15 change0.00.20.60.00.2-0.7-0.80.60.6-0.1-0.30.3
Intermittent access intake escalation0.00.10.20.1-0.1-0.5-0.50.30.30.10.00.5
Intermittent access intake escalation 20.00.10.2-0.00.1-0.3-0.20.30.30.20.00.5
Intermitt. access day 1 inactive lever presses0.11.73.51.5-1.11.51.9-0.4-0.41.71.11.3
Intermitt. access day 15 inactive lever presses0.42.04.21.3-1.21.62.1-0.8-0.81.81.31.5
Intermitt. access escalation Index0.10.30.70.5-0.40.40.3-0.5-0.50.70.50.9
Intermittent access day 1 total infusions0.41.25.3-2.30.40.0-0.9-1.4-1.4-0.70.5-0.4
Intermittent access day 15 total infusions0.10.31.2-1.1-0.0-0.2-0.6-0.7-0.7-0.20.40.2
Intermittent access terminal intake (last 3 days)0.20.41.6-1.30.7-0.4-0.8-0.3-0.3-0.5-0.0-0.2
Intermittent access total infusions0.40.41.5-1.20.1-0.0-0.6-1.0-1.0-0.30.50.1
Intermittent access day 1 locomotion0.10.20.6-0.6-0.10.30.2-0.8-0.8-0.00.4-0.4
Intermittent access day 15 total locomotion0.20.61.8-1.30.3-0.7-1.2-0.5-0.5-0.8-0.1-0.5
Intermittent access total locomotion0.20.20.5-0.1-0.50.30.1-0.7-0.70.30.50.3
Intermittent access standard deviation0.00.20.4-0.1-0.40.30.2-0.3-0.30.50.60.6
Left kidney weight0.75.927.1-5.21.4-1.5-3.1-1.5-1.4-2.6-0.1-1.0
Right kidney weight0.74.925.6-5.10.6-0.9-2.5-1.9-1.9-1.90.5-0.5
Cocaine induced anxiety0.10.10.60.80.00.20.60.20.20.2-0.1-0.4
Post-drug Anxiety0.70.81.90.11.0-0.9-0.41.01.0-0.8-1.0-1.4
Baseline Anxiety0.30.60.9-0.50.8-1.0-1.00.60.6-0.9-0.7-0.6
Tail length0.95.07.7-2.42.6-2.5-2.81.21.2-2.7-2.0-2.1
Length with tail1.35.78.8-2.72.9-2.6-2.81.21.2-3.0-1.8-2.5
Length without tail0.10.62.5-1.60.7-0.6-0.8-0.5-0.5-0.90.2-0.7
Times rat made contact with spout1.01.14.5-2.11.2-0.7-1.3-0.3-0.3-1.2-0.2-0.5
Lifetime Intake0.50.61.7-1.30.10.1-0.5-1.1-1.1-0.30.60.1
Liver weight, left1.22.17.1-2.7-1.00.2-0.9-2.1-2.1-0.51.10.3
Liver weight, right0.50.83.1-1.8-0.2-0.4-1.2-1.0-1.0-0.80.4-0.3
Locomotor activity0.10.10.4-0.20.4-0.2-0.1-0.0-0.0-0.4-0.2-0.6
Locomotor testing distance0.10.20.6-0.70.1-0.2-0.3-0.8-0.8-0.30.2-0.2
Locomotor testing rearing0.10.30.8-0.3-0.30.40.1-0.9-0.90.30.70.6
Locomotion in novel chamber0.30.51.1-0.11.1-0.6-0.60.90.9-0.4-0.7-0.0
Locomotion in novel chamber post-restriction0.41.32.1-0.51.5-1.1-1.11.01.0-1.2-1.2-1.4
Fecal boli incidents, locomotor time 10.10.31.8-1.3-0.1-0.2-0.8-0.3-0.2-0.10.10.3
Change in fecal boli incidents, locomotor task1.21.32.90.81.7-1.1-0.41.41.4-0.8-1.2-1.0
Time >=10cm from walls, locomotor time 13.54.36.30.31.9-2.3-1.82.52.5-2.0-2.4-2.2
Bouts of movement, locomotor time 12.02.54.91.1-2.21.61.4-1.4-1.41.71.51.7
Total resting periods, locomotor time 10.80.92.21.0-1.50.90.9-0.8-0.80.90.70.8
Rest time, locomotor task time 11.42.23.30.51.5-1.5-1.01.81.8-1.3-1.8-1.7
Distance moved, locomotor task time 10.30.91.5-0.6-0.81.00.5-1.2-1.20.81.21.0
Vertical activity count, locomotor time 10.10.50.9-0.9-0.60.5-0.0-1.0-1.00.40.90.7
Time >=10cm from walls, locomotor time 20.10.20.50.70.7-0.3-0.20.40.5-0.3-0.4-0.1
Bouts of movement, locomotor time 20.10.20.60.8-0.50.20.60.00.00.30.0-0.4
Total resting periods, locomotor time 20.00.20.60.8-0.60.20.60.10.10.30.0-0.4
Rest time, locomotor task time 20.40.71.4-0.00.5-0.9-0.81.21.2-0.7-0.9-0.9
Distance moved, locomotor task time 20.10.10.3-0.0-0.00.30.2-0.5-0.50.10.40.3
Vertical activity count, locomotor time 20.10.10.5-0.70.5-0.1-0.4-0.3-0.2-0.3-0.00.2
Light reinforcement 10.41.92.8-1.61.3-1.5-1.60.80.7-1.7-1.3-1.4
Light reinforcement 20.30.62.5-1.60.5-0.8-0.9-0.1-0.2-1.0-0.3-0.6
Bone: marrow area0.10.30.6-0.5-0.80.2-0.4-0.7-0.70.10.60.6
Bone: maximum diameter1.02.03.2-0.3-1.41.50.8-1.8-1.81.11.71.5
Bone: maximum force0.61.21.60.6-1.31.21.1-1.0-1.01.21.21.0
Bone: maximum moment0.61.21.60.6-1.21.21.2-1.0-1.01.21.31.1
Mean time between licks in bursts0.10.31.2-1.1-0.60.0-0.3-0.8-0.8-0.30.4-0.2
Mean num. licks in bursts0.10.20.4-0.10.40.30.4-0.6-0.60.10.60.1
Cd content in liver0.60.71.10.6-1.11.01.0-0.5-0.50.90.70.7
Co content in liver1.11.32.0-0.31.2-1.4-1.21.21.2-1.1-1.3-0.9
Cu content in liver0.50.61.60.30.3-0.8-0.40.70.7-1.0-0.7-1.3
Fe content in liver0.70.91.81.2-0.71.21.3-0.3-0.31.10.70.8
K content in liver0.50.51.5-0.3-1.20.70.7-0.8-0.80.30.80.2
Mg content in liver0.00.10.2-0.0-0.50.20.3-0.1-0.1-0.10.1-0.3
Mn content in liver1.41.63.41.8-1.41.41.8-0.2-0.11.50.71.0
Na content in liver1.01.12.5-1.40.6-1.0-1.00.50.5-1.3-0.9-1.6
Rb content in liver0.20.20.6-0.8-0.2-0.5-0.7-0.1-0.1-0.7-0.2-0.4
Se content in liver0.40.51.71.2-0.30.61.30.50.50.5-0.2-0.5
Sr content in liver0.10.10.60.8-0.10.20.30.10.10.40.10.4
Zn content in liver0.91.11.8-0.80.9-1.2-1.00.90.8-1.3-1.1-1.3
Bone: minimum diameter0.20.31.61.3-0.50.20.40.50.50.4-0.10.3
Time in familiar zone, hab. session 10.10.10.3-0.10.5-0.6-0.40.30.3-0.4-0.3-0.2
Time in novel zone, hab. session 10.20.30.7-0.7-0.30.3-0.0-0.8-0.80.20.60.3
Total zone transitions, hab. session 10.50.71.40.80.7-0.7-0.11.21.2-0.4-1.1-0.8
Total locomotion distance, hab. session 10.30.40.90.70.2-0.5-0.10.91.0-0.2-0.8-0.4
Locomotion velocity, hab. session 10.50.71.80.80.4-0.6-0.21.31.3-0.3-1.1-0.6
Time in familiar zone, hab. session 20.40.41.5-1.20.3-0.6-0.6-0.3-0.3-0.9-0.1-0.8
Time in novel zone, hab. session 20.40.41.50.7-0.70.60.3-0.1-0.10.90.41.2
Total zone transitions, hab. session 20.40.51.3-0.21.1-0.7-0.30.60.6-0.6-0.7-1.1
Total locomotion distance, hab. session 20.20.30.9-0.11.0-0.3-0.00.50.6-0.3-0.5-0.6
Locomotion velocity, hab. session 20.10.20.7-0.00.8-0.00.30.30.4-0.1-0.4-0.5
Novel to familiar place preference ratio0.10.10.20.3-0.40.40.3-0.2-0.20.30.30.4
Novelty place preference0.00.10.20.1-0.40.30.1-0.1-0.10.20.20.3
Time in novel zone, NPP test0.00.00.10.2-0.20.1-0.00.20.20.1-0.00.2
Total zone transitions, NPP test0.20.30.90.90.10.10.80.50.50.3-0.3-0.4
Total locomotion distance, NPP test0.30.41.00.90.5-0.20.31.01.00.0-0.7-0.4
Locomotion velocity, NPP test0.10.20.70.80.10.20.70.40.40.4-0.2-0.0
Intraocular pressure1.42.36.32.51.1-0.80.12.22.2-0.1-1.5-0.6
Delta distance traveled before/after self-admin0.30.31.1-1.00.40.4-0.0-0.8-0.8-0.10.6-0.1
Delta ambulatory time before/after self-admin0.30.51.8-1.30.9-0.4-0.6-0.2-0.2-0.8-0.3-0.8
Parametrial fat weight0.81.82.8-0.71.3-1.5-1.41.71.6-1.2-1.5-0.9
Pavlov. Cond. lever latency0.20.20.60.8-0.5-0.4-0.20.70.70.0-0.40.1
Pavlov. Cond. magazine entry latency1.72.23.7-1.91.9-1.4-1.70.40.4-1.9-1.0-1.5
Pavlov. Cond. change in total contacts0.40.41.1-0.71.1-0.6-0.80.40.4-0.7-0.6-0.6
Pavlov. Cond. index score0.50.62.1-1.41.1-0.4-0.7-0.3-0.3-0.8-0.1-0.7
Pavlov. Cond. latency score0.50.62.0-1.41.2-0.4-0.8-0.2-0.2-0.9-0.2-0.7
Pavlov. Cond. lever contacts0.10.10.6-0.40.8-0.0-0.0-0.1-0.1-0.3-0.1-0.5
Pavlov. Cond. magazine entry number1.72.15.92.4-1.71.31.8-0.1-0.11.80.71.3
Pavlov. Cond. intertrial magazine entries3.03.65.90.01.5-2.4-2.02.32.3-1.7-2.3-1.3
Pavlov. Cond. lever-magazine prob. diff.0.30.31.1-1.10.8-0.2-0.4-0.3-0.3-0.6-0.0-0.5
Pavlov. Cond. response bias0.70.92.6-1.61.3-0.6-0.9-0.2-0.2-1.1-0.3-0.9
Pavlov. Cond. lever latency2.23.05.7-1.31.5-1.9-1.51.41.4-2.0-1.9-2.4
Pavlov. Cond. magazine entry latency3.24.58.2-0.6-2.32.01.1-2.9-2.91.62.62.0
Pavlov. Cond. change in total contacts1.94.75.81.6-2.42.32.2-2.0-2.02.32.32.3
Pavlov. Cond. index score3.75.87.70.9-2.62.51.9-2.6-2.62.42.82.7
Pavlov. Cond. latency score4.06.48.70.7-2.72.61.9-2.9-2.92.42.92.8
Pavlov. Cond. lever contacts2.63.96.81.6-1.72.11.8-1.6-1.62.32.12.6
Pavlov. Cond. magazine entry number4.96.310.30.12.6-2.5-1.53.23.2-2.1-3.0-2.7
Pavlov. Cond. intertrial magazine entries0.40.81.7-0.11.1-0.5-0.01.21.2-0.6-1.1-1.3
Pavlov. Cond. lever-magazine prob. diff.4.06.28.30.8-2.72.62.0-2.8-2.82.42.92.8
Pavlov. Cond. response bias2.83.96.41.2-1.92.21.7-1.8-1.82.22.22.5
Time in closed arm before self-admin0.50.91.4-0.11.1-0.9-0.80.90.9-1.1-1.2-1.1
Time in closed arm after self-admin0.60.71.10.8-1.11.00.7-0.8-0.80.60.70.8
Time in open arm before self-admin0.40.51.6-1.30.4-0.6-0.80.10.1-0.8-0.3-1.2
Time in open arm after self-admin0.40.40.9-1.00.8-0.8-0.40.20.2-0.6-0.3-0.9
Bone: periosteal estimation0.61.42.50.4-1.61.20.8-1.2-1.21.21.31.5
Bone: periosteal perimeter0.30.61.60.2-1.30.80.4-0.8-0.80.70.90.8
Bone: post-yield work0.10.20.5-0.70.6-0.4-0.40.10.1-0.4-0.3-0.6
Progressive ratio test 1 active lever presses0.50.92.3-0.9-0.90.80.2-1.5-1.50.41.10.5
Progressive ratio test 1 breakpoint0.50.92.2-0.8-0.90.80.2-1.5-1.50.41.10.5
Progressive ratio test 1 inactive lever presses0.20.50.9-0.6-0.20.90.6-0.9-0.90.50.90.4
Progressive ratio test 2 active lever presses0.60.93.1-1.80.8-0.4-1.1-0.9-0.9-0.90.2-0.4
Progressive ratio test 2 breakpoint0.70.93.3-1.80.9-0.5-1.1-0.8-0.8-1.00.1-0.5
Progressive ratio test 2 inactive lever presses0.31.11.8-1.21.3-1.1-1.20.30.2-1.2-0.7-1.3
Incentive Sensitization - Responses0.51.53.6-1.91.4-1.2-1.8-0.1-0.2-1.4-0.4-0.8
Incentive Sensitization - Breakpoint0.71.63.5-1.91.6-1.3-1.8-0.0-0.0-1.5-0.6-0.9
Sum of active levers in priming session hrs 5-62.62.53.71.3-1.51.91.8-1.3-1.31.81.71.5
Progressive ratio0.00.10.20.2-0.40.40.5-0.2-0.10.20.10.0
Food seeking constrained by brief footshock0.10.10.20.1-0.1-0.3-0.30.30.3-0.4-0.3-0.4
Seeking ratio, punishment vs. effort0.00.00.10.1-0.3-0.2-0.3-0.1-0.1-0.10.00.1
Retroperitoneal fat weight1.14.99.8-3.11.9-2.5-3.11.01.0-2.5-1.7-1.8
Reaction time number correct0.10.41.41.2-0.10.40.70.60.60.6-0.20.4
Reaction time mean minus median0.21.52.50.9-1.61.31.1-1.1-1.11.21.21.3
Reaction time mean minus median AUC0.10.41.00.4-1.00.70.4-0.5-0.50.60.70.7
Reaction time num false alarms0.91.53.7-1.90.8-1.3-1.70.40.4-1.4-1.0-1.1
Reaction time num false alarms AUC0.92.14.5-2.10.9-1.6-2.00.50.5-1.8-1.2-1.5
Reaction time trials correct on left0.10.41.41.2-0.10.40.70.60.60.6-0.20.4
Reaction time trials on left0.10.52.01.4-0.20.50.90.60.60.7-0.10.5
Reaction time mean0.30.71.10.9-0.91.01.0-0.4-0.41.10.61.0
Reaction time mean AUC0.20.60.90.7-0.81.00.9-0.3-0.30.90.60.9
Median of all reaction times0.20.30.50.6-0.50.70.7-0.1-0.10.70.30.7
Reaction time omissions1.93.08.52.9-2.11.52.1-0.2-0.22.11.01.5
Reaction time false alarm rate1.82.56.5-2.60.9-1.7-2.20.20.2-1.9-1.1-1.6
Reaction time premature initiation rate1.11.83.8-2.00.9-1.5-1.80.30.2-1.7-0.8-1.5
Reaction time premature initiations0.20.71.2-0.80.6-1.0-1.10.60.5-1.1-0.8-1.0
Std. dev. reaction times0.30.81.41.0-1.21.01.0-0.5-0.51.00.71.0
Reaction time trials completed0.10.52.01.4-0.20.50.90.60.60.7-0.10.5
Reaction time trials AUC0.20.52.11.4-0.30.61.00.50.50.80.00.6
Run reversals in cocaine runway, females2.22.53.5-0.51.7-1.9-1.61.41.4-1.8-1.7-1.9
Run reversals in cocaine runway, males0.80.91.40.0-0.91.20.8-1.0-1.01.11.11.0
Latency to leave start box in cocaine runway0.81.21.80.2-1.41.11.2-1.1-1.01.11.11.1
Latency to leave start box in cocaine runway, F0.20.31.0-0.2-1.00.30.1-0.6-0.40.40.50.6
Latency to leave start box in cocaine runway, M1.01.02.50.8-0.71.21.6-0.8-0.81.00.90.6
Std. dev. time between licks in bursts0.30.62.7-1.7-0.4-0.3-0.8-0.7-0.7-0.50.3-0.1
Total sessions with >9 infusions0.30.41.5-1.20.3-0.1-0.5-0.8-0.8-0.30.3-0.0
Short access day 1 total inactive lever presses0.20.30.60.1-0.70.60.7-0.6-0.60.60.80.3
Short access day 10 total inactive lever presses0.10.71.81.40.20.21.11.11.10.6-0.4-0.2
Short access day 1 total infusions0.10.20.4-0.60.6-0.1-0.5-0.5-0.5-0.30.2-0.0
Short access day 10 total infusions0.71.22.5-0.3-0.91.10.5-1.6-1.60.81.21.1
Short access total infusions0.40.51.6-0.90.00.4-0.1-1.3-1.30.10.80.3
Short access day 1 locomotion0.00.10.2-0.10.2-0.4-0.40.30.3-0.2-0.2-0.2
Short access day 10 total locomotion0.62.44.61.6-1.41.71.8-0.5-0.52.21.22.0
Short access total locomotion0.10.10.40.3-0.40.30.50.10.10.70.20.4
One hour access (0.3 mA shock)0.30.41.6-1.30.0-0.4-1.0-0.2-0.3-0.5-0.00.0
Compulsive drug intake0.10.10.3-0.6-0.2-0.3-0.2-0.3-0.3-0.3-0.1-0.2
One hour access (shock baseline)0.10.10.3-0.3-0.20.4-0.1-0.4-0.40.30.50.5
Social response proportion1.11.47.42.70.2-0.10.81.31.30.9-0.50.5
Social responses1.52.04.21.21.2-1.6-0.82.02.1-0.7-1.6-0.8
Social time1.11.79.23.0-0.60.51.51.01.01.2-0.10.3
Soleus weight0.30.91.9-1.11.4-1.0-1.10.20.2-1.2-0.7-1.0
Bone: stiffness0.20.30.70.0-0.80.50.4-0.6-0.60.50.60.4
Tibialis anterior weight0.82.86.12.51.6-1.10.12.42.4-0.3-1.7-0.6
Time to tail flick, vehicle, before self-admin0.50.61.5-0.2-1.20.80.6-0.8-0.80.70.90.4
Time to tail flick, vehicle, after self-admin0.20.40.9-0.6-0.30.80.5-0.9-0.90.30.90.1
Time to tail flick, test, before self-admin6.77.712.01.2-3.53.02.3-2.5-2.53.03.03.4
Time to tail flick, test, after self-admin1.21.33.10.30.7-1.1-0.71.81.8-0.7-1.2-1.1
Delta time to tail flick, vehicle, before/after SA0.10.10.30.10.60.30.5-0.3-0.30.20.30.2
Delta time to tail flick, test, before/after SA6.78.311.90.03.0-3.2-2.13.53.5-2.6-3.2-3.2
Tibia length0.10.31.7-1.31.00.0-0.3-0.3-0.3-0.30.1-0.1
Ambulatory time before self-admin0.31.01.5-0.1-1.21.20.7-1.2-1.20.81.21.0
Ambulatory time after self-admin0.60.91.9-0.7-0.61.20.5-1.4-1.40.51.10.7
Bone: tissue strength0.20.20.50.20.7-0.20.10.50.5-0.2-0.4-0.5
Total heroin consumption0.50.61.51.0-0.11.01.2-0.3-0.30.90.30.6
Bone: trabecular number0.00.10.30.40.3-0.20.30.10.1-0.2-0.1-0.5
Bone: trabecular spacing1.21.82.90.4-1.51.71.4-1.3-1.21.41.41.5
Bone: trabecular thickness0.91.34.12.00.4-0.70.21.61.6-0.1-1.2-0.5
Bone: trabecular tissue density0.20.41.00.8-1.00.60.7-0.2-0.20.70.40.4
Water consumed over 24 hours0.30.62.0-1.40.2-0.3-1.0-0.8-0.8-0.50.40.4
Number of responses in last shaping day1.72.24.00.3-2.01.41.0-1.7-1.71.41.71.6