Hub : Genes

Esyt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Esyt1 0.33 0.15 0.0e+00 0.2 0.17 0.18 0.18 2.8e-22 3.1e-19 7.0e-20 5.9e-21
2 OFC gene expression Esyt1 0.31 0.2 4.9e-05 0.19 0.14 0.15 0.16 2.4e-05 3.4e-04 2.3e-04 1.2e-04
3 OFC mRNA stability Esyt1 0.27 0.16 1.7e-04 0.17 0.15 0.14 0.16 7.0e-05 1.9e-04 2.6e-04 1.2e-04
4 BLA gene expression Esyt1 0.16 0.11 3.2e-08 0.14 0.09 0.14 0.14 3.8e-08 2.6e-05 5.5e-08 4.4e-08
5 IL gene expression Esyt1 0.2 0.13 2.4e-03 0.02 -0 -0.01 0.01 9.4e-02 4.2e-01 9.7e-01 1.8e-01
6 Liver intron excision ratio chr7_932781_935331 0.07 0.05 2.9e-07 0.06 0.05 0.04 0.06 3.2e-07 4.8e-06 2.5e-05 5.8e-07
7 PL gene expression Esyt1 0.37 0.18 0.0e+00 0.19 0.19 0.19 0.19 2.4e-20 1.4e-20 4.5e-20 2.1e-20
8 BLA mRNA stability Esyt1 0.17 0.12 3.2e-06 0.05 0.1 0.09 0.1 1.4e-03 6.9e-06 1.8e-05 9.4e-06
9 Brain mRNA stability Esyt1 0.11 0.06 1.3e-08 0.04 0.08 0.07 0.07 1.3e-04 1.3e-07 2.6e-07 8.1e-07
10 Liver intron excision ratio chr7_931043_935331 0.24 0.14 0.0e+00 0.12 0.16 0.14 0.14 1.2e-13 6.3e-17 1.3e-15 1.0e-15
11 NAcc mRNA stability Esyt1 0.16 0.12 4.9e-07 0.05 0.05 0.04 0.05 3.4e-06 6.3e-07 5.7e-06 1.6e-06
12 Liver mRNA stability Esyt1 0.2 0.12 1.4e-15 0.13 0.14 0.13 0.13 3.0e-14 3.3e-15 4.1e-14 2.9e-14
13 Liver gene expression Esyt1 0.07 0.05 1.5e-05 0.03 0.03 0.03 0.02 8.0e-04 2.5e-04 5.4e-04 1.3e-03
14 Adipose mRNA stability Esyt1 0.23 0.13 2.8e-16 0.11 0.14 0.12 0.12 5.4e-12 9.6e-15 1.0e-12 2.8e-13
15 PL mRNA stability Esyt1 0.1 0.06 7.7e-10 0.09 0.09 0.09 0.08 9.3e-10 1.1e-09 1.1e-09 2.6e-09
16 Adipose gene expression Esyt1 0.11 0.07 4.7e-08 0.06 0.07 0.07 0.06 1.5e-07 3.1e-08 6.9e-08 1.1e-07
17 IL mRNA stability Esyt1 0.26 0.17 8.8e-03 0.07 0.02 0.04 0.05 7.5e-03 1.2e-01 4.6e-02 2.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density2.64.47.6-1.0-1.0-1.0-1.0-1.00.81.62.32.42.22.52.72.72.7-2.72.7-2.7
Area under the delay curve0.20.20.7-0.3-0.3-0.3-0.1-0.10.00.50.40.30.60.80.50.50.6-0.50.6-0.4
BMI with tail3.511.426.34.94.94.95.05.05.1-4.1-2.7-2.53.3-1.0-0.11.50.00.70.80.7
BMI without tail0.91.93.81.91.91.91.92.01.6-1.8-1.5-1.40.7-0.9-0.6-0.1-0.60.9-0.30.8
Body weight0.62.45.32.22.22.22.32.32.3-1.8-1.3-1.31.5-0.4-0.20.6-0.10.50.30.4
Weight adjusted by age0.30.40.70.30.30.30.40.4-0.2-0.5-0.7-0.7-0.6-0.8-0.8-0.7-0.80.8-0.80.7
Bone surface5.39.415.7-1.8-1.8-1.8-1.9-1.80.92.53.53.72.83.54.03.73.9-3.93.8-3.9
Bone volume5.59.315.9-1.6-1.6-1.6-1.6-1.61.12.33.43.63.03.64.03.84.0-3.93.9-3.9
Breakpoint value in progressive ratio session0.91.02.9-1.3-1.3-1.3-1.3-1.3-1.70.80.30.3-1.5-0.4-0.6-1.0-0.60.5-0.80.2
Number of licking bursts2.42.95.22.22.22.22.32.31.7-2.1-1.9-1.90.5-1.2-1.1-0.5-1.01.4-0.81.4
Context. condit. distance diff. score0.10.20.40.60.60.60.60.60.5-0.5-0.4-0.40.2-0.2-0.2-0.0-0.20.2-0.10.2
Locomotion velocity, session 11.21.32.5-0.4-0.4-0.4-0.4-0.30.50.81.21.11.41.61.51.51.5-1.41.5-1.4
Locomotion distance, session 11.72.23.4-1.0-1.0-1.0-1.2-1.00.11.41.71.81.21.81.81.71.8-1.81.8-1.8
Locomotion velocity, session 22.83.25.1-1.7-1.7-1.7-1.8-1.7-0.52.02.22.30.82.02.01.61.9-2.11.8-2.1
Locomotion distance, session 23.54.97.9-2.5-2.5-2.5-2.7-2.5-1.42.82.72.60.42.42.01.41.9-2.11.6-2.1
Locomotion velocity, session 32.22.56.3-2.3-2.3-2.3-2.3-2.3-2.51.91.21.1-1.70.4-0.1-0.8-0.1-0.2-0.5-0.2
Locomotion distance, session 30.10.10.1-0.2-0.2-0.2-0.3-0.2-0.40.1-0.1-0.1-0.4-0.1-0.3-0.3-0.30.2-0.30.2
Stereotopy head waving bouts, day 33.03.67.5-2.7-2.7-2.7-2.7-2.7-2.52.41.91.9-1.30.90.6-0.20.5-1.00.2-1.0
Stereotopy head waving duration, day 31.82.14.6-2.1-2.1-2.1-2.0-2.1-1.91.71.41.5-1.20.40.5-0.20.4-0.80.1-0.8
Locomotion velocity, session 70.20.20.4-0.4-0.4-0.4-0.4-0.4-0.10.50.60.60.30.60.60.50.6-0.60.5-0.6
Locomotion distance, session 70.40.50.80.50.50.50.60.60.1-0.7-0.9-0.9-0.6-0.9-0.9-0.8-0.90.9-0.80.9
Stereotopy head waving bouts, day 71.61.82.6-1.4-1.4-1.4-1.3-1.4-0.71.61.61.60.51.51.31.01.3-1.41.2-1.4
Stereotopy head waving duration, day 71.92.33.4-1.5-1.5-1.5-1.4-1.4-0.61.71.81.80.81.81.61.31.6-1.71.5-1.7
Locomotion velocity, session 83.03.55.3-1.8-1.8-1.8-1.8-1.8-0.82.32.32.20.92.32.01.62.0-2.01.8-2.0
Locomotion distance, session 80.40.61.2-0.9-0.9-0.9-1.0-0.9-0.61.10.90.90.10.90.60.40.6-0.70.5-0.7
Degree of sensitization distance0.20.20.70.70.70.70.70.70.8-0.6-0.3-0.30.6-0.10.10.30.10.00.20.0
Degree of sensitization stereotypy0.60.71.5-0.2-0.2-0.2-0.2-0.20.40.60.80.81.11.21.11.11.1-1.01.1-1.0
Conditioned locomotion1.82.13.41.51.51.51.51.50.5-1.6-1.8-1.8-0.4-1.5-1.5-1.2-1.51.6-1.31.7
Cocaine response after cond. corrected2.73.04.42.12.12.12.12.11.2-2.0-2.0-2.1-0.2-1.6-1.5-1.0-1.41.7-1.21.7
Cocaine response after cond. not corrected3.13.44.92.12.12.12.22.21.2-2.2-2.2-2.2-0.3-1.8-1.6-1.1-1.61.8-1.41.8
Cocaine response before conditioning0.40.50.9-1.0-1.0-1.0-1.0-1.0-0.70.70.70.8-0.20.40.40.20.4-0.50.3-0.6
Saline control response0.30.40.70.80.80.80.80.80.6-0.8-0.7-0.70.2-0.5-0.4-0.2-0.40.5-0.30.5
Bone: connectivity density1.52.44.2-0.8-0.8-0.8-0.8-0.80.61.21.71.81.61.82.02.02.0-2.02.0-2.0
Bone: cortical apparent density0.81.02.31.51.51.51.51.41.5-1.2-0.8-0.80.8-0.4-0.10.3-0.10.30.10.3
Bone: cortical area1.21.74.20.50.50.50.50.51.8-0.00.81.02.11.21.72.01.7-1.51.9-1.5
Bone: cortical porosity0.30.30.6-0.3-0.3-0.3-0.4-0.30.20.40.60.70.40.50.70.70.7-0.80.7-0.8
Bone: cortical porosity0.60.71.5-0.1-0.1-0.1-0.2-0.10.80.30.80.91.00.81.11.21.1-1.11.2-1.1
Bone: cortical thickness0.71.23.71.21.21.21.21.11.9-0.9-0.10.01.70.40.91.30.9-0.61.1-0.6
Bone: cortical thickness0.60.71.41.21.21.21.01.00.9-1.1-1.0-1.00.2-0.7-0.6-0.2-0.50.7-0.40.7
Bone: cortical tissue density0.60.71.71.31.31.31.31.31.3-1.0-0.7-0.70.6-0.4-0.20.2-0.10.30.00.3
Condit. Reinf. active minus inactive responses0.91.02.3-1.4-1.4-1.4-1.5-1.4-1.41.31.01.0-0.90.40.2-0.20.2-0.4-0.0-0.4
Condit. Reinf. active-inactive response ratio0.20.20.7-0.2-0.2-0.2-0.3-0.2-0.6-0.1-0.2-0.2-0.9-0.7-0.6-0.7-0.60.5-0.70.5
Condit. Reinf. active responses2.12.54.6-2.1-2.1-2.1-2.1-2.1-1.52.11.91.8-0.41.31.10.51.0-1.30.7-1.3
Condit. Reinf. inactive responses2.02.43.8-1.7-1.7-1.7-1.7-1.8-1.01.91.91.80.31.71.41.01.4-1.51.2-1.5
Incentive salience index mean1.21.52.5-1.5-1.5-1.5-1.5-1.5-0.91.61.51.5-0.01.21.00.61.0-1.10.8-1.1
Condit. Reinf. lever presses2.23.05.4-1.2-1.2-1.2-1.2-1.2-0.01.82.02.01.42.32.11.82.1-2.02.0-2.0
Condit. Reinf. active minus inactive responses1.11.33.9-1.1-1.1-1.1-1.1-1.1-1.80.4-0.2-0.1-2.0-1.0-1.1-1.5-1.20.8-1.40.8
Condit. Reinf. active-inactive response ratio1.71.83.8-0.1-0.1-0.1-0.0-0.0-1.2-0.6-1.1-1.2-1.9-1.6-1.8-1.9-1.81.6-1.91.6
Condit. Reinf. active responses0.50.71.9-1.2-1.2-1.2-1.2-1.2-1.40.70.50.5-1.2-0.3-0.2-0.6-0.30.1-0.5-0.0
Condit. Reinf. inactive responses0.50.61.0-0.8-0.8-0.8-0.8-0.8-0.30.80.91.00.20.70.80.60.7-0.80.6-0.8
Condit. Reinf. lever presses1.21.74.8-1.5-1.5-1.5-1.5-1.5-2.20.90.20.2-2.0-0.7-0.9-1.4-0.90.7-1.20.6
Condit. Reinf. lever reinforcers received0.40.61.7-0.9-0.9-0.9-0.9-0.9-1.30.40.10.2-1.3-0.6-0.5-0.9-0.60.4-0.70.3
Conditioned reinforcement - actives0.30.30.7-0.3-0.3-0.3-0.3-0.30.30.10.60.80.40.20.80.70.7-0.80.7-0.8
Conditioned reinforcement - inactives1.92.14.31.71.71.71.71.71.0-2.1-1.7-1.5-0.4-2.0-1.2-0.8-1.21.2-1.01.2
Conditioned locomotion1.01.32.7-1.6-1.6-1.6-1.6-1.6-1.51.01.11.2-1.1-0.10.3-0.20.2-0.7-0.0-0.6
Patch foraging indifference point 0 sec1.62.67.62.32.32.32.22.22.8-1.8-0.9-0.82.0-0.20.41.20.5-0.10.9-0.2
Patch foraging indifference point AUC0.30.30.8-0.8-0.8-0.8-0.7-0.7-0.90.70.40.3-0.60.2-0.1-0.4-0.1-0.0-0.30.1
Delay disc. indifference point, 0s delay2.12.35.70.30.30.30.40.41.50.61.11.12.42.11.92.22.0-1.82.1-1.6
Delay disc. indifference point, 16s delay0.20.20.6-0.8-0.8-0.8-0.5-0.6-0.60.60.40.4-0.10.40.20.10.2-0.30.1-0.2
Delay disc. indifference point, 2s delay0.50.51.3-0.1-0.1-0.10.10.10.50.50.60.51.11.10.91.00.9-0.71.0-0.8
Delay disc. indifference point, 24s delay0.10.10.40.20.20.20.30.30.3-0.0-0.0-0.10.60.50.20.40.3-0.20.3-0.1
Delay disc. indifference point, 4s delay1.11.21.9-1.1-1.1-1.1-1.0-1.0-0.41.31.31.20.61.41.10.91.1-1.21.0-1.1
Delay disc. indifference point, 8s delay0.30.30.60.30.30.30.50.5-0.1-0.4-0.7-0.7-0.3-0.4-0.7-0.6-0.60.7-0.60.7
Indifference point function ln k0.10.20.50.60.60.60.50.50.6-0.7-0.4-0.30.2-0.5-0.10.1-0.10.3-0.00.1
Indifference point function log k0.10.20.50.60.60.60.50.50.6-0.7-0.4-0.30.2-0.5-0.10.1-0.10.3-0.00.1
Patch foraging total patch changes 0 sec1.52.56.92.32.32.32.12.22.6-1.9-1.1-0.91.7-0.40.31.00.30.10.7-0.1
Patch foraging total patch changes 12 sec1.31.73.31.81.81.81.81.81.4-1.7-1.5-1.40.4-1.0-0.8-0.3-0.80.9-0.51.0
Patch foraging total patch changes 18 sec0.00.00.00.10.10.10.20.20.1-0.1-0.1-0.10.10.0-0.00.1-0.0-0.10.00.0
Patch foraging total patch changes 24 sec0.20.30.90.60.60.60.50.50.9-0.3-0.0-0.00.90.40.40.70.5-0.40.6-0.3
Patch foraging total patch changes 6 sec0.91.43.61.71.71.71.61.71.9-1.4-0.8-0.71.2-0.30.10.60.20.10.40.1
Patch foraging time to switch 0 sec0.30.51.20.20.20.20.20.10.70.20.40.41.10.90.91.00.9-0.91.0-0.7
Patch foraging water rate 0 sec0.91.42.11.31.31.31.21.30.7-1.5-1.4-1.4-0.4-1.4-1.1-0.8-1.11.3-1.01.1
Patch foraging water rate 12 sec1.21.82.81.51.51.51.41.50.8-1.7-1.6-1.6-0.3-1.5-1.2-0.9-1.21.5-1.01.2
Patch foraging water rate 18 sec2.63.46.10.90.90.90.80.8-0.5-1.6-2.1-2.1-1.9-2.4-2.4-2.3-2.42.5-2.42.2
Patch foraging water rate 24 sec4.56.39.52.22.22.22.22.20.5-2.7-3.0-3.1-1.4-3.0-2.8-2.4-2.83.1-2.62.8
Patch foraging water rate 6 sec1.21.73.60.10.10.10.00.1-0.9-0.7-1.2-1.1-1.9-1.9-1.7-1.9-1.81.6-1.81.4
Seeking ratio, delayed vs. immediate footshock1.01.22.0-1.4-1.4-1.4-1.4-1.4-0.81.21.31.4-0.20.70.80.50.8-0.90.6-1.0
Distance traveled before self-admin0.60.61.4-1.1-1.1-1.1-1.2-1.2-0.91.10.80.8-0.40.50.3-0.00.3-0.30.1-0.5
Distance traveled after self-admin0.20.20.4-0.5-0.5-0.5-0.6-0.6-0.30.50.50.6-0.00.30.40.20.4-0.50.3-0.4
Extensor digitorum longus weight3.413.427.35.25.25.25.25.24.3-4.7-3.8-3.71.9-2.3-1.6-0.2-1.52.2-0.82.2
Bone: elastic displacement0.00.00.1-0.1-0.1-0.1-0.1-0.20.10.10.20.20.20.20.20.20.2-0.30.2-0.3
Bone: elastic work0.40.51.60.50.50.50.50.41.1-0.20.20.31.20.70.81.00.8-0.71.0-0.7
Bone: endosteal estimation0.40.92.50.80.80.80.90.81.6-0.50.20.31.40.51.01.31.0-0.81.1-0.8
Bone: endosteal perimeter0.71.42.2-1.1-1.1-1.1-0.9-0.9-0.11.11.41.50.61.21.41.21.3-1.51.2-1.5
Epididymis fat weight0.10.20.4-0.3-0.3-0.3-0.2-0.3-0.60.1-0.1-0.2-0.6-0.2-0.5-0.6-0.50.5-0.50.3
Delta time in closed arm before/after self-admin4.14.06.61.71.71.71.71.70.3-2.2-2.4-2.4-1.4-2.6-2.3-2.0-2.32.3-2.22.3
Delta time in open arm before/after self-admin0.50.51.60.80.80.80.70.71.2-0.4-0.1-0.21.30.60.50.80.6-0.20.7-0.3
Diff in mean of infusions in LGA sessions0.90.92.6-1.4-1.4-1.4-1.4-1.4-1.61.00.60.6-1.3-0.1-0.2-0.7-0.3-0.0-0.5-0.0
Delay discount exponential model param0.20.20.60.40.40.40.20.20.1-0.5-0.4-0.3-0.5-0.8-0.4-0.4-0.50.4-0.50.4
Extinction: sum of active levers before priming1.81.85.1-1.2-1.2-1.2-1.2-1.2-2.30.7-0.2-0.3-2.2-0.8-1.3-1.8-1.31.0-1.61.1
Active lever presses in extinction session 60.90.91.8-1.2-1.2-1.2-1.3-1.3-1.11.31.00.9-0.40.80.40.10.4-0.50.2-0.5
Bone: final force1.42.36.61.41.41.41.31.32.5-0.80.10.32.61.01.52.11.5-1.21.8-1.2
Bone: final moment1.42.26.41.31.31.31.31.32.5-0.80.20.32.51.01.52.01.5-1.21.8-1.2
Food consumed during 24 hour testing period0.20.20.50.60.60.60.70.70.7-0.6-0.3-0.30.5-0.10.10.30.10.10.20.1
Glucose0.91.32.91.71.71.71.71.71.7-1.4-1.0-1.01.1-0.3-0.10.4-0.10.40.20.2
Heart weight0.20.20.50.40.40.40.60.50.1-0.6-0.5-0.5-0.4-0.7-0.6-0.5-0.60.5-0.50.5
Delay discount hyperbolic model param0.20.20.70.20.20.20.00.0-0.1-0.4-0.4-0.3-0.7-0.8-0.5-0.6-0.60.5-0.60.4
Intermittent access intake day 1-15 change0.20.20.9-0.2-0.2-0.2-0.2-0.2-0.4-0.3-0.3-0.1-0.9-1.0-0.5-0.6-0.60.5-0.60.2
Intermittent access intake escalation1.51.53.80.40.40.40.40.4-0.5-1.1-1.2-1.1-1.6-1.9-1.6-1.6-1.61.5-1.61.2
Intermittent access intake escalation 21.11.12.8-0.1-0.1-0.1-0.1-0.1-1.0-0.5-0.8-0.8-1.7-1.5-1.4-1.5-1.41.3-1.51.0
Intermitt. access day 1 inactive lever presses1.31.43.50.50.50.50.50.5-0.5-1.1-1.3-1.2-1.4-1.9-1.5-1.5-1.51.4-1.51.3
Intermitt. access day 15 inactive lever presses0.80.92.5-0.4-0.4-0.4-0.4-0.4-1.2-0.2-0.5-0.5-1.6-1.2-1.1-1.3-1.21.1-1.30.8
Intermitt. access escalation Index1.21.01.9-0.6-0.6-0.6-0.6-0.60.40.71.21.30.91.01.41.31.3-1.31.3-1.3
Intermittent access day 1 total infusions0.20.20.60.50.50.50.50.50.8-0.3-0.00.00.70.20.40.60.4-0.40.5-0.2
Intermittent access day 15 total infusions0.30.30.90.60.60.60.60.60.4-0.9-0.7-0.5-0.2-0.9-0.5-0.3-0.50.5-0.40.4
Intermittent access terminal intake (last 3 days)0.10.20.60.30.30.30.30.30.8-0.40.10.20.5-0.10.40.50.4-0.30.5-0.4
Intermittent access total infusions0.20.30.60.70.70.70.70.70.8-0.8-0.5-0.40.3-0.5-0.10.1-0.10.20.00.1
Intermittent access day 1 locomotion0.00.00.00.10.10.10.10.1-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.0-0.10.2
Intermittent access day 15 total locomotion0.20.20.8-0.3-0.3-0.3-0.3-0.3-0.5-0.2-0.10.0-0.9-0.9-0.4-0.6-0.50.3-0.50.2
Intermittent access total locomotion0.10.10.2-0.5-0.5-0.5-0.5-0.5-0.40.30.30.4-0.30.00.1-0.00.1-0.20.0-0.2
Intermittent access standard deviation0.30.31.10.00.00.00.00.0-0.3-0.5-0.4-0.3-0.9-1.0-0.6-0.7-0.70.5-0.70.4
Left kidney weight0.61.63.1-0.3-0.3-0.3-0.2-0.20.80.71.21.31.61.61.71.81.7-1.51.7-1.6
Right kidney weight0.30.71.3-1.0-1.0-1.0-0.8-0.9-0.50.91.11.10.10.70.90.60.8-1.00.7-0.8
Cocaine induced anxiety2.02.33.8-1.8-1.8-1.8-1.8-1.8-1.11.91.81.70.21.61.30.91.3-1.41.1-1.4
Post-drug Anxiety2.42.74.4-1.2-1.2-1.2-1.2-1.2-0.11.72.01.91.22.11.91.71.9-1.91.8-1.9
Baseline Anxiety0.10.10.30.20.20.20.20.20.0-0.4-0.4-0.4-0.3-0.5-0.5-0.4-0.50.6-0.40.4
Tail length2.05.916.9-3.3-3.3-3.3-3.4-3.4-4.12.51.21.1-3.2-0.1-0.9-2.0-1.00.4-1.50.4
Length with tail0.83.06.7-2.5-2.5-2.5-2.6-2.6-2.52.21.51.4-1.40.80.2-0.50.2-0.5-0.2-0.5
Length without tail0.30.71.5-0.1-0.1-0.1-0.0-0.10.70.40.80.81.21.11.11.21.2-1.11.2-1.1
Times rat made contact with spout0.91.01.71.31.31.31.31.30.9-1.3-1.2-1.20.1-0.9-0.8-0.4-0.70.9-0.60.9
Lifetime Intake0.50.62.00.90.90.90.90.91.4-0.9-0.3-0.11.0-0.20.40.70.4-0.20.6-0.3
Liver weight, left1.11.83.81.81.81.81.91.91.5-1.8-1.4-1.30.5-1.1-0.7-0.2-0.60.8-0.40.9
Liver weight, right0.40.71.81.21.21.21.21.21.3-1.1-0.6-0.51.0-0.30.20.50.2-0.10.40.0
Locomotor activity2.43.87.7-2.6-2.6-2.6-2.8-2.8-2.12.52.12.0-0.61.51.10.41.0-1.40.7-1.3
Locomotor testing distance0.91.52.9-1.7-1.7-1.7-1.7-1.7-1.31.51.31.3-0.40.90.70.30.7-0.90.5-0.9
Locomotor testing rearing0.10.10.20.00.00.00.10.1-0.3-0.3-0.4-0.4-0.4-0.4-0.5-0.5-0.50.4-0.50.5
Locomotion in novel chamber0.20.20.50.60.60.60.70.70.6-0.6-0.4-0.30.2-0.4-0.10.1-0.10.2-0.00.1
Locomotion in novel chamber post-restriction1.61.94.6-2.1-2.1-2.1-1.9-1.9-2.11.71.11.0-1.40.40.0-0.6-0.0-0.2-0.3-0.3
Fecal boli incidents, locomotor time 11.11.22.01.11.11.11.21.20.4-1.2-1.4-1.4-0.3-1.1-1.1-0.9-1.11.2-1.01.2
Change in fecal boli incidents, locomotor task1.71.62.4-0.9-0.9-0.9-1.2-1.2-0.11.41.61.60.71.51.41.21.4-1.51.3-1.5
Time >=10cm from walls, locomotor time 10.80.82.00.20.20.20.30.31.00.10.60.61.41.01.11.31.2-1.01.3-1.0
Bouts of movement, locomotor time 10.20.30.8-0.8-0.8-0.8-0.5-0.5-0.90.40.10.1-0.7-0.2-0.3-0.5-0.30.1-0.40.2
Total resting periods, locomotor time 10.60.61.6-1.3-1.3-1.3-1.0-1.0-1.30.80.50.5-0.80.1-0.1-0.4-0.1-0.1-0.2-0.1
Rest time, locomotor task time 10.40.51.0-1.0-1.0-1.0-0.8-0.8-0.70.90.80.7-0.10.60.40.20.4-0.50.3-0.5
Distance moved, locomotor task time 10.80.92.00.60.60.60.40.41.3-0.00.50.61.40.81.11.41.2-1.01.3-1.0
Vertical activity count, locomotor time 10.90.92.11.41.41.41.31.31.3-1.3-0.9-0.80.4-0.8-0.30.0-0.30.4-0.10.4
Time >=10cm from walls, locomotor time 20.90.91.71.21.21.21.31.31.0-1.3-1.1-1.00.2-0.8-0.6-0.2-0.60.7-0.40.7
Bouts of movement, locomotor time 21.01.11.5-1.2-1.2-1.2-0.9-0.9-0.41.01.21.20.61.11.10.91.1-1.11.0-1.2
Total resting periods, locomotor time 21.21.31.8-1.2-1.2-1.2-0.9-0.9-0.31.11.31.40.71.31.31.11.3-1.31.2-1.3
Rest time, locomotor task time 20.60.61.0-0.6-0.6-0.6-0.5-0.5-0.00.80.90.90.71.01.00.91.0-1.00.9-1.0
Distance moved, locomotor task time 20.60.71.10.70.70.70.50.50.1-0.8-0.9-0.9-0.7-1.1-1.0-0.9-1.01.0-0.91.0
Vertical activity count, locomotor time 22.02.23.31.71.71.71.61.60.9-1.8-1.8-1.8-0.3-1.6-1.4-1.0-1.31.5-1.21.5
Light reinforcement 11.73.17.5-2.6-2.6-2.6-2.6-2.7-2.42.01.61.6-1.50.50.4-0.40.3-0.6-0.1-0.8
Light reinforcement 20.50.61.7-1.1-1.1-1.1-1.3-1.3-1.10.90.70.7-0.70.10.1-0.20.1-0.3-0.1-0.3
Bone: marrow area0.40.82.20.70.70.70.80.81.5-0.40.20.31.40.50.91.20.9-0.81.1-0.8
Bone: maximum diameter1.22.23.5-1.2-1.2-1.2-1.2-1.20.01.31.81.90.91.51.81.61.7-1.81.7-1.8
Bone: maximum force1.32.37.01.61.61.61.61.52.7-1.1-0.10.12.50.81.31.91.4-1.01.7-1.0
Bone: maximum moment1.32.36.91.61.61.61.61.52.6-1.0-0.10.12.50.81.31.91.4-1.01.7-1.0
Mean time between licks in bursts0.40.51.7-0.7-0.7-0.7-0.7-0.7-1.10.40.0-0.0-1.3-0.6-0.6-1.0-0.70.6-0.80.6
Mean num. licks in bursts0.50.61.2-1.1-1.1-1.1-1.1-1.1-0.90.90.80.8-0.30.50.40.10.4-0.60.2-0.6
Cd content in liver0.20.20.50.60.60.60.70.70.6-0.4-0.2-0.20.50.10.10.30.1-0.10.20.1
Co content in liver0.60.72.0-0.8-0.8-0.8-0.8-0.8-1.30.4-0.1-0.1-1.4-0.6-0.8-1.1-0.80.6-1.00.7
Cu content in liver1.01.22.90.70.70.70.70.71.6-0.20.50.71.70.81.31.61.3-1.21.5-1.3
Fe content in liver0.50.71.10.90.90.91.11.10.6-1.0-1.0-0.9-0.0-0.8-0.6-0.4-0.60.7-0.50.8
K content in liver1.01.01.5-1.1-1.1-1.1-0.9-0.9-0.51.11.21.20.31.01.00.81.0-1.10.9-1.0
Mg content in liver1.41.42.1-1.1-1.1-1.1-0.9-0.9-0.31.31.51.40.71.51.41.21.4-1.41.3-1.3
Mn content in liver4.14.67.3-1.6-1.6-1.6-1.4-1.40.12.02.62.61.72.62.72.42.6-2.62.5-2.7
Na content in liver0.30.30.7-0.2-0.2-0.2-0.1-0.10.30.40.60.50.80.80.80.80.8-0.60.8-0.6
Rb content in liver0.91.12.40.40.40.40.40.41.3-0.10.70.81.50.81.31.51.3-1.41.5-1.3
Se content in liver0.10.10.1-0.3-0.3-0.3-0.2-0.2-0.20.40.30.30.10.30.30.20.3-0.30.2-0.2
Sr content in liver1.21.12.10.20.20.20.10.1-0.5-0.7-1.0-1.0-1.4-1.5-1.4-1.5-1.41.3-1.41.3
Zn content in liver2.12.46.0-0.8-0.8-0.8-0.7-0.7-1.9-0.0-0.9-1.0-2.4-1.5-1.9-2.3-1.91.7-2.11.9
Bone: minimum diameter0.50.92.10.10.10.10.10.21.10.20.80.91.30.91.31.51.3-1.21.4-1.2
Time in familiar zone, hab. session 12.32.26.2-2.0-2.0-2.0-2.1-2.0-2.51.50.70.6-1.9-0.1-0.6-1.3-0.60.3-1.00.3
Time in novel zone, hab. session 12.12.15.41.41.41.41.51.42.3-0.70.20.32.30.91.41.91.4-1.21.7-1.2
Total zone transitions, hab. session 11.52.13.2-1.3-1.3-1.3-1.4-1.3-0.41.71.71.70.81.81.61.31.6-1.61.4-1.6
Total locomotion distance, hab. session 13.75.27.8-2.3-2.3-2.3-2.3-2.2-0.92.62.82.80.92.62.41.92.4-2.52.1-2.5
Locomotion velocity, hab. session 12.84.05.9-2.2-2.2-2.2-2.2-2.1-1.12.42.42.40.52.11.91.41.9-2.11.6-2.1
Time in familiar zone, hab. session 22.22.36.6-1.8-1.8-1.8-1.7-1.8-2.61.10.20.2-2.4-0.7-1.1-1.8-1.20.8-1.50.8
Time in novel zone, hab. session 22.62.67.51.81.81.81.71.82.7-1.0-0.10.02.60.91.32.01.4-1.01.7-1.0
Total zone transitions, hab. session 21.62.14.5-0.0-0.0-0.0-0.10.01.20.71.31.32.01.82.02.12.0-1.82.1-1.8
Total locomotion distance, hab. session 21.21.62.6-1.1-1.1-1.1-1.2-1.1-0.31.41.51.50.81.61.41.21.4-1.41.3-1.4
Locomotion velocity, hab. session 21.82.44.0-1.3-1.3-1.3-1.4-1.2-0.31.71.91.81.02.01.81.51.8-1.81.7-1.8
Novel to familiar place preference ratio1.92.05.71.11.11.11.01.22.1-0.40.40.52.41.21.52.01.6-1.31.8-1.3
Novelty place preference1.51.54.30.80.80.80.70.91.7-0.20.50.62.11.21.51.81.5-1.31.7-1.3
Time in novel zone, NPP test1.61.64.61.11.11.11.01.22.0-0.40.30.42.11.01.41.81.4-1.21.6-1.2
Total zone transitions, NPP test0.50.71.70.10.10.10.10.10.80.30.60.61.31.11.11.21.1-0.91.2-0.9
Total locomotion distance, NPP test0.91.22.4-0.4-0.4-0.4-0.5-0.40.50.91.21.11.31.61.41.41.4-1.41.5-1.4
Locomotion velocity, NPP test0.91.22.4-0.7-0.7-0.7-0.8-0.70.11.11.31.21.01.61.41.31.4-1.31.3-1.3
Intraocular pressure0.81.22.6-0.3-0.3-0.3-0.3-0.2-1.2-0.1-0.8-0.9-1.6-1.0-1.5-1.6-1.51.5-1.51.3
Delta distance traveled before/after self-admin0.00.00.10.10.10.10.10.10.3-0.10.10.10.30.10.20.30.2-0.30.3-0.1
Delta ambulatory time before/after self-admin0.30.30.6-0.0-0.0-0.0-0.1-0.10.40.20.50.50.70.60.70.80.7-0.80.8-0.6
Parametrial fat weight0.10.10.3-0.1-0.1-0.1-0.1-0.1-0.3-0.1-0.2-0.2-0.5-0.4-0.4-0.5-0.40.4-0.50.4
Pavlov. Cond. lever latency1.01.22.20.70.70.70.60.6-0.1-1.1-1.3-1.3-1.0-1.5-1.4-1.3-1.41.3-1.31.3
Pavlov. Cond. magazine entry latency0.60.82.2-1.2-1.2-1.2-1.2-1.2-1.51.00.50.5-1.20.1-0.3-0.7-0.30.1-0.50.1
Pavlov. Cond. change in total contacts0.10.10.30.40.40.40.40.50.6-0.2-0.00.00.40.20.20.30.2-0.20.3-0.2
Pavlov. Cond. index score0.70.81.5-1.0-1.0-1.0-0.9-0.9-0.51.21.21.10.21.10.90.60.9-0.90.7-0.9
Pavlov. Cond. latency score1.11.42.2-1.1-1.1-1.1-1.1-1.1-0.41.51.51.40.51.51.31.01.2-1.31.1-1.3
Pavlov. Cond. lever contacts1.51.73.4-0.7-0.7-0.7-0.6-0.60.31.31.51.51.31.81.71.61.7-1.61.6-1.6
Pavlov. Cond. magazine entry number0.20.30.70.80.80.80.70.70.8-0.8-0.5-0.40.5-0.3-0.10.2-0.00.10.10.1
Pavlov. Cond. intertrial magazine entries0.50.61.10.20.20.20.00.1-0.4-0.5-0.8-0.8-1.0-1.0-1.0-1.0-1.01.0-1.01.0
Pavlov. Cond. lever-magazine prob. diff.0.70.91.6-1.1-1.1-1.1-1.0-1.0-0.61.31.21.10.11.00.80.50.8-0.90.7-0.9
Pavlov. Cond. response bias0.40.51.0-1.0-1.0-1.0-0.9-0.9-0.91.00.70.6-0.50.50.2-0.10.2-0.30.0-0.3
Pavlov. Cond. lever latency0.81.02.31.51.51.51.51.51.5-1.2-0.8-0.80.9-0.3-0.10.4-0.00.20.20.2
Pavlov. Cond. magazine entry latency1.21.43.1-1.7-1.7-1.7-1.8-1.8-1.61.51.11.1-0.90.50.3-0.30.2-0.5-0.0-0.5
Pavlov. Cond. change in total contacts0.30.41.1-0.9-0.9-0.9-0.9-0.9-1.00.60.40.4-0.9-0.1-0.2-0.5-0.20.0-0.40.0
Pavlov. Cond. index score0.91.22.8-1.6-1.6-1.6-1.6-1.6-1.71.20.80.8-1.20.1-0.1-0.6-0.1-0.2-0.3-0.2
Pavlov. Cond. latency score1.11.43.1-1.7-1.7-1.7-1.7-1.7-1.71.41.11.0-1.00.50.2-0.30.2-0.4-0.1-0.4
Pavlov. Cond. lever contacts0.60.82.3-1.2-1.2-1.2-1.2-1.2-1.50.80.40.4-1.2-0.1-0.4-0.8-0.40.2-0.60.2
Pavlov. Cond. magazine entry number1.11.32.91.71.71.71.71.71.5-1.4-1.1-1.10.9-0.5-0.30.2-0.20.50.00.5
Pavlov. Cond. intertrial magazine entries0.81.11.81.31.31.31.31.30.9-1.4-1.2-1.20.1-1.0-0.8-0.4-0.80.9-0.60.9
Pavlov. Cond. lever-magazine prob. diff.1.01.32.8-1.7-1.7-1.7-1.7-1.7-1.61.30.90.9-1.10.30.1-0.40.0-0.3-0.2-0.3
Pavlov. Cond. response bias0.91.23.4-1.5-1.5-1.5-1.6-1.6-1.81.10.50.5-1.5-0.2-0.4-0.9-0.50.2-0.70.2
Time in closed arm before self-admin1.01.12.1-0.3-0.3-0.3-0.2-0.20.70.71.01.01.41.41.41.41.4-1.21.4-1.3
Time in closed arm after self-admin0.20.20.50.60.60.60.60.60.7-0.6-0.3-0.20.3-0.40.00.2-0.00.20.1-0.0
Time in open arm before self-admin0.30.41.1-0.1-0.1-0.1-0.1-0.1-0.5-0.4-0.4-0.3-1.1-1.1-0.7-0.9-0.80.5-0.80.5
Time in open arm after self-admin0.70.81.41.21.21.21.21.20.9-1.1-1.0-1.00.4-0.6-0.5-0.2-0.50.6-0.30.7
Bone: periosteal estimation1.12.25.40.70.70.70.70.72.1-0.10.81.02.31.31.92.21.9-1.62.1-1.6
Bone: periosteal perimeter1.01.73.1-0.6-0.6-0.6-0.4-0.50.70.81.41.51.41.41.81.81.7-1.81.8-1.8
Bone: post-yield work0.20.20.60.70.70.70.60.60.8-0.7-0.4-0.30.5-0.20.00.30.00.00.20.0
Progressive ratio test 1 active lever presses0.80.81.81.31.31.31.31.31.3-1.3-0.8-0.70.6-0.6-0.20.2-0.20.30.00.3
Progressive ratio test 1 breakpoint0.80.82.01.31.31.31.31.31.4-1.2-0.7-0.60.8-0.5-0.00.4-0.00.20.20.2
Progressive ratio test 1 inactive lever presses0.10.10.30.10.10.10.10.10.4-0.50.00.2-0.1-0.60.10.20.1-0.10.1-0.3
Progressive ratio test 2 active lever presses0.30.30.90.70.70.70.70.71.0-0.8-0.4-0.20.5-0.40.10.30.10.10.2-0.1
Progressive ratio test 2 breakpoint0.20.20.60.20.20.20.20.20.8-0.20.30.40.70.20.70.80.6-0.50.7-0.6
Progressive ratio test 2 inactive lever presses0.20.20.80.40.40.40.40.40.9-0.40.10.30.6-0.10.50.70.5-0.30.6-0.5
Incentive Sensitization - Responses0.00.00.1-0.3-0.3-0.3-0.3-0.3-0.20.10.10.2-0.2-0.20.0-0.1-0.0-0.0-0.0-0.1
Incentive Sensitization - Breakpoint0.10.10.2-0.4-0.4-0.4-0.4-0.4-0.20.30.40.5-0.10.10.30.10.2-0.30.2-0.4
Sum of active levers in priming session hrs 5-60.20.10.4-0.5-0.5-0.5-0.5-0.5-0.60.40.20.1-0.5-0.1-0.2-0.3-0.20.2-0.30.1
Progressive ratio0.81.02.01.41.41.41.31.31.2-1.4-1.0-0.90.4-0.8-0.4-0.1-0.40.5-0.20.6
Food seeking constrained by brief footshock0.91.12.7-1.5-1.5-1.5-1.4-1.4-1.71.40.80.6-1.00.5-0.1-0.5-0.1-0.0-0.3-0.1
Seeking ratio, punishment vs. effort1.21.53.7-1.8-1.8-1.8-1.7-1.7-1.91.71.00.9-1.00.70.1-0.50.0-0.2-0.2-0.3
Retroperitoneal fat weight1.34.49.23.03.03.03.03.02.8-2.7-2.1-2.01.4-1.2-0.70.2-0.61.0-0.20.9
Reaction time number correct1.11.62.41.51.51.51.41.50.7-1.5-1.5-1.6-0.1-1.2-1.1-0.8-1.11.2-0.91.3
Reaction time mean minus median0.71.02.3-1.4-1.4-1.4-1.5-1.5-1.31.31.00.9-0.70.60.3-0.20.3-0.40.0-0.4
Reaction time mean minus median AUC2.43.14.9-1.9-1.9-1.9-2.0-2.0-0.92.22.22.10.52.01.71.21.7-1.81.5-1.7
Reaction time num false alarms0.40.51.11.01.01.00.90.90.8-1.0-0.8-0.80.3-0.5-0.4-0.1-0.40.5-0.20.5
Reaction time num false alarms AUC0.71.01.61.31.31.31.11.10.8-1.3-1.2-1.20.1-0.9-0.8-0.5-0.81.0-0.60.8
Reaction time trials correct on left1.11.62.41.51.51.51.41.50.7-1.5-1.5-1.6-0.1-1.2-1.1-0.8-1.11.2-0.91.3
Reaction time trials on left1.01.42.11.41.41.41.41.40.7-1.4-1.4-1.5-0.1-1.1-1.0-0.7-1.01.1-0.81.2
Reaction time mean1.31.83.3-1.7-1.7-1.7-1.4-1.5-1.01.81.61.60.11.51.10.71.1-1.30.9-1.2
Reaction time mean AUC0.91.22.0-1.2-1.2-1.2-1.0-1.1-0.51.41.41.30.31.31.10.81.1-1.21.0-1.1
Median of all reaction times0.91.22.2-1.3-1.3-1.3-1.0-1.1-0.71.51.41.30.31.41.00.81.0-1.20.9-1.1
Reaction time omissions0.10.10.3-0.2-0.2-0.2-0.0-0.10.20.20.40.40.40.40.50.50.5-0.50.5-0.5
Reaction time false alarm rate0.00.10.20.30.30.30.20.20.5-0.2-0.1-0.10.40.10.20.30.2-0.00.2-0.1
Reaction time premature initiation rate0.91.23.3-0.9-0.9-0.9-0.9-0.8-1.80.3-0.3-0.4-1.8-1.0-1.2-1.5-1.20.9-1.41.0
Reaction time premature initiations1.31.94.1-0.1-0.1-0.1-0.1-0.0-1.4-0.6-1.2-1.3-1.9-1.7-1.9-2.0-1.91.6-2.01.7
Std. dev. reaction times0.81.11.9-1.3-1.3-1.3-1.2-1.2-0.91.41.21.2-0.11.00.80.50.8-0.90.6-0.9
Reaction time trials completed1.01.42.11.41.41.41.41.40.7-1.4-1.4-1.5-0.1-1.1-1.0-0.7-1.01.1-0.81.2
Reaction time trials AUC1.31.92.91.61.61.61.51.60.7-1.6-1.7-1.7-0.2-1.3-1.3-0.9-1.21.3-1.11.4
Run reversals in cocaine runway, females1.41.42.4-1.6-1.6-1.6-1.6-1.6-1.31.61.31.3-0.41.00.70.20.7-1.00.4-0.7
Run reversals in cocaine runway, males1.71.63.2-1.8-1.8-1.8-1.6-1.6-1.31.61.41.5-0.50.90.80.30.7-0.90.5-0.9
Latency to leave start box in cocaine runway1.51.63.0-0.4-0.4-0.4-0.5-0.50.80.91.31.31.61.71.71.71.7-1.51.7-1.6
Latency to leave start box in cocaine runway, F2.93.25.9-0.6-0.6-0.6-0.6-0.61.01.31.81.82.22.42.42.42.4-2.22.4-2.2
Latency to leave start box in cocaine runway, M0.70.71.20.60.60.60.20.2-0.1-0.8-1.0-1.0-0.8-1.1-1.0-1.0-1.01.0-1.01.0
Std. dev. time between licks in bursts1.01.22.1-1.0-1.0-1.0-1.0-1.0-0.31.11.41.50.51.11.31.01.2-1.31.1-1.3
Total sessions with >9 infusions1.11.22.7-0.0-0.0-0.0-0.0-0.01.30.11.01.21.40.81.51.71.5-1.31.6-1.5
Short access day 1 total inactive lever presses0.00.00.10.10.10.10.10.10.3-0.30.00.10.0-0.30.10.20.1-0.00.1-0.2
Short access day 10 total inactive lever presses0.70.82.30.50.50.50.50.5-0.1-1.0-1.0-0.9-1.0-1.5-1.1-1.0-1.11.0-1.10.9
Short access day 1 total infusions1.31.43.40.40.40.40.40.41.8-0.20.81.01.70.71.61.81.6-1.31.7-1.5
Short access day 10 total infusions0.40.41.40.90.90.90.90.91.2-0.9-0.3-0.20.7-0.30.20.50.2-0.10.4-0.1
Short access total infusions1.21.34.10.90.90.90.90.92.0-0.60.30.51.80.51.31.71.3-0.91.5-1.1
Short access day 1 locomotion0.30.30.8-0.4-0.4-0.4-0.4-0.40.20.30.60.80.40.30.80.70.7-0.90.7-0.7
Short access day 10 total locomotion0.80.82.9-0.8-0.8-0.8-0.8-0.8-1.40.1-0.10.0-1.7-1.2-0.9-1.2-0.90.5-1.10.5
Short access total locomotion0.10.10.3-0.4-0.4-0.4-0.4-0.4-0.20.20.40.5-0.1-0.10.30.20.3-0.40.2-0.4
One hour access (0.3 mA shock)0.20.20.60.60.60.60.60.60.8-0.6-0.4-0.30.4-0.2-0.00.2-0.00.20.10.0
Compulsive drug intake0.10.10.30.30.30.30.30.30.5-0.1-0.0-0.10.50.30.20.30.2-0.00.3-0.1
One hour access (shock baseline)0.40.51.20.60.60.60.60.60.2-1.0-0.8-0.7-0.5-1.1-0.7-0.6-0.70.7-0.70.7
Social response proportion0.91.01.8-1.3-1.3-1.3-1.2-1.2-1.01.41.11.0-0.01.00.70.30.7-0.70.5-0.7
Social responses5.67.214.7-3.8-3.8-3.8-3.8-3.8-3.33.52.82.6-1.31.81.10.11.1-1.50.6-1.5
Social time0.70.91.91.41.41.41.31.31.1-1.1-1.0-1.00.6-0.4-0.4-0.0-0.30.5-0.20.6
Soleus weight2.98.618.84.34.34.34.34.34.3-3.5-2.5-2.42.8-0.8-0.21.1-0.10.70.50.8
Bone: stiffness1.93.09.42.22.22.22.22.23.1-1.7-0.7-0.52.50.30.91.71.0-0.51.4-0.5
Tibialis anterior weight0.62.04.42.12.12.12.12.12.1-1.7-1.2-1.11.4-0.3-0.10.60.00.30.30.4
Time to tail flick, vehicle, before self-admin2.82.84.8-1.8-1.8-1.8-1.7-1.7-0.61.82.12.20.51.51.81.41.7-1.81.5-2.0
Time to tail flick, vehicle, after self-admin0.60.61.4-0.1-0.1-0.1-0.1-0.1-0.8-0.2-0.6-0.7-1.1-0.9-1.1-1.2-1.10.9-1.11.0
Time to tail flick, test, before self-admin1.81.82.7-1.4-1.4-1.4-1.3-1.3-0.61.51.61.70.51.41.41.11.3-1.51.2-1.4
Time to tail flick, test, after self-admin0.91.01.5-0.7-0.7-0.7-0.7-0.70.10.91.21.20.81.21.21.11.2-1.21.2-1.2
Delta time to tail flick, vehicle, before/after SA2.42.44.31.41.41.41.41.40.2-1.5-1.9-2.1-0.7-1.4-1.8-1.5-1.71.8-1.62.0
Delta time to tail flick, test, before/after SA0.40.30.70.00.00.00.00.0-0.5-0.2-0.5-0.6-0.8-0.6-0.8-0.9-0.80.8-0.80.7
Tibia length0.41.23.6-1.5-1.5-1.5-1.6-1.6-1.91.20.60.5-1.40.0-0.4-0.9-0.40.2-0.70.2
Ambulatory time before self-admin0.20.20.4-0.6-0.6-0.6-0.6-0.6-0.50.50.40.3-0.30.20.1-0.10.1-0.0-0.0-0.2
Ambulatory time after self-admin0.10.10.1-0.2-0.2-0.2-0.3-0.3-0.00.30.30.40.10.20.30.20.3-0.30.3-0.3
Bone: tissue strength1.81.85.31.81.81.81.91.82.3-1.4-0.7-0.61.80.00.51.10.6-0.20.9-0.2
Total heroin consumption1.51.73.5-1.9-1.9-1.9-1.9-1.9-1.71.81.31.3-0.70.90.5-0.00.5-0.70.2-0.7
Bone: trabecular number1.93.04.3-1.7-1.7-1.7-1.7-1.7-0.51.92.12.10.91.91.91.51.9-1.91.7-1.9
Bone: trabecular spacing3.74.87.41.51.51.51.51.5-0.3-2.0-2.5-2.6-1.9-2.7-2.7-2.5-2.72.6-2.62.6
Bone: trabecular thickness6.47.613.6-1.1-1.1-1.1-1.2-1.11.32.03.03.13.03.43.73.63.7-3.53.7-3.5
Bone: trabecular tissue density3.85.310.53.23.23.23.23.22.7-3.0-2.4-2.31.1-1.6-1.1-0.1-1.01.4-0.61.4
Water consumed over 24 hours0.81.02.60.50.50.50.50.51.3-0.10.50.61.60.91.21.51.3-1.11.4-1.1
Number of responses in last shaping day0.30.30.6-0.8-0.8-0.8-0.8-0.8-0.70.30.40.5-0.8-0.4-0.0-0.3-0.1-0.2-0.2-0.2