Hub : Genes

Ervk-21l3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Ervk-21l3 0.56 0.15 0.0e+00 0.34 0.33 0.35 0.36 3.2e-15 1.3e-14 1.5e-15 7.3e-16
2 IL gene expression Ervk-21l3 0.38 0.14 6.8e-05 0.06 0.12 0.11 0.15 1.2e-02 9.0e-04 1.6e-03 1.9e-04
3 PL gene expression Ervk-21l3 0.48 0.1 0.0e+00 0.45 0.39 0.5 0.42 2.0e-54 3.8e-45 4.1e-63 1.6e-49
4 BLA gene expression Ervk-21l3 0.78 0 0.0e+00 0.45 0.35 0.53 0.5 4.4e-26 1.6e-19 2.4e-32 6.0e-30
5 Brain gene expression Ervk-21l3 0.55 0.12 0.0e+00 0.42 0.46 0.46 0.47 4.5e-42 4.6e-47 6.5e-48 1.1e-48
6 LHb gene expression Ervk-21l3 0.4 0.14 1.9e-05 0.22 0.1 0.16 -0.01 6.5e-06 2.4e-03 1.4e-04 4.6e-01
7 OFC gene expression Ervk-21l3 0.5 0.14 2.2e-07 0.2 0.22 0.23 0.24 1.3e-05 7.3e-06 4.0e-06 1.9e-06
8 NAcc gene expression Ervk-21l3 0.4 0.1 0.0e+00 0.38 0.39 0.39 0.39 2.1e-60 1.3e-62 7.1e-64 2.1e-63
9 pVTA gene expression Ervk-21l3 0.55 0.15 0.0e+00 0.47 0.45 0.46 0.46 1.6e-41 7.2e-40 9.1e-41 6.1e-41
10 RMTg gene expression Ervk-21l3 0.41 0.16 6.6e-06 0.22 0.04 0.14 -0.01 1.8e-06 3.6e-02 1.6e-04 9.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.03.75.02.22.1-1.9-2.22.2-2.01.9-1.6-1.4-1.4
Area under the delay curve0.10.20.4-0.30.4-0.4-0.50.5-0.60.5-0.5-0.30.0
BMI with tail1.03.54.9-2.2-1.71.82.0-2.01.5-1.71.62.02.1
BMI without tail0.00.20.4-0.20.6-0.4-0.30.4-0.60.6-0.4-0.2-0.2
Body weight0.00.10.30.3-0.10.30.5-0.50.3-0.20.20.30.3
Weight adjusted by age0.10.40.7-0.9-0.70.60.6-0.60.5-0.70.40.50.5
Bone surface3.05.97.12.42.3-2.5-2.72.6-2.12.3-2.4-2.5-2.5
Bone volume2.65.36.62.42.1-2.4-2.62.5-2.02.2-2.2-2.3-2.3
Breakpoint value in progressive ratio session1.22.13.30.3-1.21.31.6-1.61.3-1.51.61.71.8
Number of licking bursts0.10.41.00.81.0-0.6-0.40.5-1.00.8-0.4-0.1-0.1
Context. condit. distance diff. score0.50.61.3-1.1-0.60.71.0-0.90.5-0.50.50.70.8
Locomotion velocity, session 11.11.21.51.21.2-1.2-1.11.1-0.91.1-1.0-1.1-1.1
Locomotion distance, session 10.10.10.60.80.6-0.3-0.10.1-0.40.3-0.2-0.0-0.1
Locomotion velocity, session 20.70.81.50.81.2-1.0-0.90.9-1.01.1-0.8-0.7-0.6
Locomotion distance, session 20.10.10.30.40.10.20.6-0.40.1-0.10.40.50.4
Locomotion velocity, session 30.10.20.2-0.50.1-0.4-0.40.3-0.30.3-0.5-0.5-0.5
Locomotion distance, session 34.04.65.60.92.3-2.3-2.22.2-2.22.4-2.3-2.1-2.2
Stereotopy head waving bouts, day 30.20.21.2-1.1-0.2-0.1-0.20.3-0.00.2-0.5-0.6-0.6
Stereotopy head waving duration, day 30.10.21.1-1.0-0.40.40.3-0.20.2-0.30.10.20.2
Locomotion velocity, session 70.20.30.50.00.5-0.6-0.40.4-0.70.5-0.6-0.5-0.5
Locomotion distance, session 70.30.30.80.90.7-0.6-0.50.4-0.50.6-0.4-0.4-0.5
Stereotopy head waving bouts, day 71.41.72.2-0.11.3-1.3-1.31.5-1.41.5-1.5-1.3-1.2
Stereotopy head waving duration, day 71.51.82.40.41.5-1.3-1.51.5-1.61.5-1.4-1.2-1.2
Locomotion velocity, session 80.00.10.30.6-0.00.00.3-0.20.1-0.10.10.10.0
Locomotion distance, session 80.20.20.6-0.00.00.40.7-0.60.0-0.20.40.70.7
Degree of sensitization distance1.71.82.30.1-1.31.41.5-1.51.4-1.51.51.31.4
Degree of sensitization stereotypy1.01.21.60.21.2-1.1-1.11.2-1.21.3-1.2-1.0-1.0
Conditioned locomotion0.00.10.20.50.1-0.2-0.20.1-0.10.1-0.1-0.2-0.2
Cocaine response after cond. corrected0.91.31.8-0.2-1.11.11.2-1.41.1-1.21.21.31.3
Cocaine response after cond. not corrected0.91.41.9-0.2-1.11.11.2-1.31.1-1.21.31.41.4
Cocaine response before conditioning0.60.71.00.41.0-0.9-1.00.9-0.90.9-0.8-0.7-0.8
Saline control response0.71.05.02.21.4-0.7-0.40.5-0.90.9-0.3-0.1-0.2
Bone: connectivity density4.97.89.82.83.0-2.8-3.13.1-2.92.8-2.5-2.3-2.3
Bone: cortical apparent density0.20.30.6-0.60.7-0.4-0.60.5-0.70.7-0.5-0.1-0.0
Bone: cortical area0.10.20.40.60.5-0.4-0.10.2-0.40.4-0.4-0.5-0.4
Bone: cortical porosity1.01.11.7-0.8-1.31.01.2-1.21.3-1.10.90.60.6
Bone: cortical porosity0.30.30.7-0.4-0.80.50.8-0.70.8-0.60.3-0.0-0.0
Bone: cortical thickness0.40.71.2-1.0-0.70.81.1-0.90.7-0.60.60.70.8
Bone: cortical thickness2.02.56.0-0.5-0.71.61.6-1.50.7-1.21.82.42.4
Bone: cortical tissue density0.30.40.8-0.50.8-0.6-0.70.7-0.90.8-0.7-0.3-0.2
Condit. Reinf. active minus inactive responses1.71.93.0-0.61.5-1.4-1.01.2-1.41.7-1.7-1.5-1.5
Condit. Reinf. active-inactive response ratio0.20.20.4-0.60.5-0.40.10.1-0.40.6-0.5-0.3-0.3
Condit. Reinf. active responses1.92.53.6-0.21.7-1.6-1.41.6-1.61.9-1.8-1.6-1.6
Condit. Reinf. inactive responses2.43.14.01.41.7-1.8-2.01.9-1.81.7-1.8-1.8-1.7
Incentive salience index mean3.64.66.00.12.2-2.3-2.02.2-2.12.5-2.4-2.4-2.3
Condit. Reinf. lever presses3.45.16.90.52.1-2.4-2.42.4-2.12.4-2.5-2.6-2.5
Condit. Reinf. active minus inactive responses0.30.51.10.40.4-0.7-0.50.5-0.50.5-0.8-1.0-1.0
Condit. Reinf. active-inactive response ratio0.20.30.9-0.6-0.90.50.5-0.60.6-0.80.40.20.2
Condit. Reinf. active responses0.10.10.40.60.2-0.2-0.10.1-0.30.1-0.3-0.4-0.3
Condit. Reinf. inactive responses0.20.30.50.4-0.20.60.6-0.60.4-0.40.60.60.7
Condit. Reinf. lever presses0.00.00.0-0.1-0.20.20.2-0.20.1-0.20.00.10.1
Condit. Reinf. lever reinforcers received0.00.00.20.40.1-0.1-0.00.0-0.10.0-0.2-0.3-0.2
Conditioned reinforcement - actives0.00.00.0-0.1-0.20.20.1-0.20.1-0.20.10.10.1
Conditioned reinforcement - inactives0.00.00.1-0.3-0.30.20.1-0.20.2-0.20.1-0.1-0.1
Conditioned locomotion0.00.00.1-0.10.1-0.1-0.20.1-0.10.1-0.3-0.3-0.3
Patch foraging indifference point 0 sec0.20.61.30.40.5-0.7-0.50.6-0.60.7-1.1-1.1-1.1
Patch foraging indifference point AUC0.10.32.01.40.4-0.3-0.50.3-0.60.1-0.1-0.2-0.1
Delay disc. indifference point, 0s delay0.91.11.41.00.9-1.2-1.11.1-0.90.9-1.0-1.0-1.0
Delay disc. indifference point, 16s delay1.11.52.4-1.0-1.11.31.3-1.21.1-1.21.31.31.6
Delay disc. indifference point, 2s delay0.20.21.4-1.2-0.30.20.2-0.20.1-0.10.10.30.5
Delay disc. indifference point, 24s delay0.00.00.1-0.3-0.10.10.1-0.1-0.0-0.0-0.2-0.10.1
Delay disc. indifference point, 4s delay1.51.62.20.21.3-1.4-1.51.5-1.41.4-1.4-1.2-1.0
Delay disc. indifference point, 8s delay0.30.40.9-0.20.7-0.7-0.80.7-0.90.7-0.8-0.5-0.3
Indifference point function ln k0.10.42.0-1.40.1-0.3-0.10.3-0.10.5-0.7-0.7-0.7
Indifference point function log k0.10.42.0-1.40.1-0.3-0.10.3-0.10.5-0.7-0.7-0.7
Patch foraging total patch changes 0 sec0.10.20.60.00.1-0.3-0.10.2-0.20.3-0.7-0.8-0.7
Patch foraging total patch changes 12 sec1.52.03.11.81.6-1.3-1.21.2-1.71.4-1.4-1.2-1.2
Patch foraging total patch changes 18 sec1.12.66.42.51.7-1.5-1.51.4-1.71.4-1.4-1.4-1.3
Patch foraging total patch changes 24 sec0.82.63.61.91.5-1.5-1.51.5-1.61.5-1.7-1.7-1.6
Patch foraging total patch changes 6 sec0.10.31.01.00.4-0.4-0.40.3-0.70.3-0.4-0.3-0.2
Patch foraging time to switch 0 sec0.00.00.20.30.4-0.00.00.1-0.10.30.10.00.0
Patch foraging water rate 0 sec0.10.20.5-0.0-0.70.40.3-0.50.6-0.60.40.20.2
Patch foraging water rate 12 sec0.10.30.6-0.80.3-0.6-0.70.6-0.50.5-0.6-0.4-0.4
Patch foraging water rate 18 sec1.43.04.10.11.5-1.8-1.91.9-1.61.8-2.0-1.9-2.0
Patch foraging water rate 24 sec0.91.31.9-0.30.9-1.2-1.21.2-1.01.1-1.4-1.2-1.2
Patch foraging water rate 6 sec1.72.45.12.31.7-1.6-1.61.5-1.51.5-1.2-1.2-1.3
Seeking ratio, delayed vs. immediate footshock0.40.62.4-1.5-0.50.70.6-0.60.4-0.50.60.90.8
Distance traveled before self-admin0.40.81.8-1.3-1.01.00.8-0.81.0-0.90.70.60.6
Distance traveled after self-admin0.51.01.9-1.4-1.11.10.9-0.91.0-1.00.80.80.8
Extensor digitorum longus weight0.41.72.4-0.6-1.31.31.5-1.51.3-1.41.41.21.3
Bone: elastic displacement0.10.10.3-0.6-0.0-0.2-0.10.10.00.2-0.4-0.5-0.6
Bone: elastic work0.81.02.0-1.4-1.10.91.2-1.11.1-1.00.80.60.7
Bone: endosteal estimation0.10.11.31.10.2-0.00.1-0.1-0.20.00.20.10.2
Bone: endosteal perimeter0.71.82.91.71.3-1.3-1.01.0-1.31.3-1.3-1.5-1.5
Epididymis fat weight0.00.10.30.40.2-0.3-0.20.2-0.20.3-0.4-0.5-0.5
Delta time in closed arm before/after self-admin0.00.00.4-0.6-0.0-0.0-0.00.0-0.10.1-0.10.10.0
Delta time in open arm before/after self-admin0.30.43.82.00.2-0.00.1-0.1-0.0-0.10.30.10.1
Diff in mean of infusions in LGA sessions0.00.10.40.60.4-0.2-0.10.2-0.20.20.00.10.0
Delay discount exponential model param0.20.30.60.3-0.60.60.6-0.60.8-0.60.60.40.1
Extinction: sum of active levers before priming0.10.21.9-1.40.1-0.1-0.10.1-0.10.3-0.3-0.1-0.0
Active lever presses in extinction session 60.50.50.8-0.70.4-0.6-0.70.7-0.60.7-0.9-0.8-0.7
Bone: final force0.10.20.30.4-0.40.40.6-0.50.5-0.40.50.30.3
Bone: final moment0.10.10.30.2-0.30.40.5-0.40.4-0.40.40.20.3
Food consumed during 24 hour testing period1.22.49.03.01.9-1.3-1.31.4-1.71.4-0.8-0.6-0.6
Glucose0.30.50.90.4-0.90.70.8-0.80.9-0.90.60.30.3
Heart weight0.10.21.0-1.00.3-0.0-0.00.1-0.50.3-0.10.40.4
Delay discount hyperbolic model param0.40.51.00.3-0.80.70.8-0.81.0-0.80.80.40.2
Intermittent access intake day 1-15 change0.52.73.61.91.7-1.7-1.61.7-1.61.7-1.5-1.5-1.6
Intermittent access intake escalation0.31.82.11.51.4-1.4-1.31.3-1.31.3-1.2-1.2-1.3
Intermittent access intake escalation 21.32.22.81.71.5-1.5-1.41.4-1.51.4-1.3-1.4-1.5
Intermitt. access day 1 inactive lever presses0.11.32.40.40.8-1.1-1.21.1-0.91.0-1.2-1.6-1.5
Intermitt. access day 15 inactive lever presses0.20.91.3-1.1-1.21.01.0-1.00.9-1.10.90.80.7
Intermitt. access escalation Index0.10.20.3-0.40.4-0.6-0.40.4-0.40.5-0.6-0.5-0.3
Intermittent access day 1 total infusions0.92.63.9-2.0-1.71.71.6-1.61.6-1.61.51.31.3
Intermittent access day 15 total infusions0.10.30.9-0.9-0.60.60.6-0.60.6-0.50.50.40.3
Intermittent access terminal intake (last 3 days)0.30.50.9-1.0-0.80.80.7-0.70.7-0.70.60.40.3
Intermittent access total infusions1.11.31.7-1.3-1.31.31.2-1.11.2-1.11.10.90.8
Intermittent access day 1 locomotion0.50.92.5-1.6-0.90.90.9-0.90.9-0.80.70.70.7
Intermittent access day 15 total locomotion0.51.92.3-1.2-1.41.51.5-1.41.5-1.41.41.21.1
Intermittent access total locomotion2.53.03.5-1.5-1.81.81.9-1.81.8-1.81.81.71.6
Intermittent access standard deviation0.21.11.50.81.0-1.1-1.01.0-1.01.1-1.0-1.2-1.2
Left kidney weight0.43.56.92.62.2-1.9-1.61.6-2.11.9-1.6-1.4-1.3
Right kidney weight0.32.06.52.51.8-1.3-0.91.0-1.51.4-1.1-1.0-0.9
Cocaine induced anxiety0.10.20.3-0.60.0-0.3-0.60.4-0.50.2-0.6-0.5-0.4
Post-drug Anxiety0.10.10.4-0.7-0.40.40.2-0.20.1-0.30.20.20.2
Baseline Anxiety0.30.40.80.2-0.30.60.9-0.70.7-0.50.90.70.8
Tail length1.68.510.43.22.9-2.9-2.93.0-2.72.8-2.6-2.9-3.1
Length with tail0.52.15.12.31.3-1.3-1.21.3-1.11.3-1.2-1.6-1.6
Length without tail0.21.21.6-0.0-1.11.11.3-1.31.2-1.21.10.91.0
Times rat made contact with spout0.00.00.1-0.20.2-0.1-0.20.2-0.30.20.00.20.2
Lifetime Intake0.70.91.2-1.1-1.11.11.0-1.01.1-1.00.90.70.6
Liver weight, left0.30.62.11.40.5-0.6-0.50.5-0.20.5-0.7-1.0-1.0
Liver weight, right1.22.03.31.81.3-1.3-1.21.2-1.01.3-1.4-1.7-1.7
Locomotor activity1.01.62.2-0.3-1.11.31.4-1.31.2-1.21.41.41.5
Locomotor testing distance0.81.92.7-0.3-1.21.41.5-1.41.3-1.41.51.61.6
Locomotor testing rearing0.10.42.41.60.8-0.4-0.20.2-0.90.4-0.00.30.3
Locomotion in novel chamber0.60.81.6-0.4-0.60.81.0-1.00.6-0.91.11.31.3
Locomotion in novel chamber post-restriction0.20.61.10.70.5-0.8-0.80.8-0.50.6-0.8-1.1-0.9
Fecal boli incidents, locomotor time 10.51.22.31.50.8-1.1-0.90.9-0.80.9-1.1-1.4-1.3
Change in fecal boli incidents, locomotor task1.92.02.80.51.6-1.5-1.71.6-1.61.6-1.3-1.0-1.2
Time >=10cm from walls, locomotor time 10.00.00.20.00.20.1-0.10.2-0.20.20.30.40.2
Bouts of movement, locomotor time 10.10.10.6-0.7-0.2-0.3-0.30.2-0.20.1-0.4-0.4-0.4
Total resting periods, locomotor time 10.20.21.1-1.1-0.1-0.3-0.40.3-0.20.2-0.5-0.5-0.5
Rest time, locomotor task time 10.10.11.0-1.0-0.40.00.0-0.10.0-0.1-0.2-0.4-0.3
Distance moved, locomotor task time 10.31.01.80.2-0.61.01.0-0.90.8-0.91.11.31.4
Vertical activity count, locomotor time 10.10.74.62.20.40.20.1-0.1-0.0-0.10.71.00.9
Time >=10cm from walls, locomotor time 20.71.92.8-1.1-1.71.51.2-1.31.5-1.61.51.11.0
Bouts of movement, locomotor time 20.00.10.7-0.8-0.0-0.1-0.10.10.00.0-0.10.20.4
Total resting periods, locomotor time 20.00.10.3-0.60.0-0.1-0.10.10.00.0-0.10.20.4
Rest time, locomotor task time 20.10.10.40.30.3-0.4-0.40.3-0.60.3-0.4-0.3-0.1
Distance moved, locomotor task time 22.53.33.8-1.4-1.91.91.9-1.91.9-1.91.81.71.6
Vertical activity count, locomotor time 20.20.61.31.2-0.30.60.6-0.60.3-0.60.91.00.9
Light reinforcement 12.09.027.95.33.4-2.7-2.62.6-2.92.7-2.2-2.3-2.2
Light reinforcement 21.63.616.44.01.9-1.6-1.51.5-1.31.5-1.1-1.4-1.4
Bone: marrow area0.10.11.21.10.20.00.1-0.2-0.1-0.00.20.20.2
Bone: maximum diameter0.40.71.40.50.7-0.9-0.50.6-0.80.9-1.1-1.2-1.1
Bone: maximum force0.10.30.50.2-0.60.50.7-0.60.7-0.60.50.30.4
Bone: maximum moment0.10.20.40.1-0.50.40.6-0.60.6-0.50.40.20.3
Mean time between licks in bursts0.20.91.70.71.2-1.0-0.90.9-1.31.1-1.0-0.6-0.7
Mean num. licks in bursts0.10.20.9-1.0-0.60.30.0-0.10.5-0.40.20.00.0
Cd content in liver0.60.71.4-1.2-0.60.91.1-1.00.3-0.60.70.80.7
Co content in liver0.20.32.2-1.5-0.50.20.4-0.30.2-0.2-0.2-0.2-0.1
Cu content in liver0.10.10.3-0.2-0.20.30.6-0.50.3-0.30.30.20.2
Fe content in liver0.81.02.60.10.3-1.0-1.21.1-0.20.6-1.2-1.6-1.6
K content in liver0.60.60.9-0.8-0.90.70.8-0.80.9-0.90.60.50.5
Mg content in liver0.10.10.2-0.3-0.40.00.2-0.10.4-0.2-0.1-0.4-0.3
Mn content in liver0.40.40.90.90.8-0.6-0.30.5-0.80.7-0.6-0.6-0.5
Na content in liver0.00.10.20.1-0.30.20.0-0.10.4-0.30.2-0.1-0.0
Rb content in liver0.50.60.80.90.9-0.8-0.70.7-0.80.8-0.8-0.7-0.6
Se content in liver1.21.54.10.70.4-1.2-1.01.0-0.20.8-1.3-2.0-2.0
Sr content in liver0.40.30.5-0.5-0.60.60.7-0.70.6-0.50.50.40.3
Zn content in liver0.80.91.2-1.0-1.00.91.1-1.10.9-1.00.90.90.9
Bone: minimum diameter0.50.92.91.71.0-0.9-0.70.8-0.90.9-0.7-0.8-0.8
Time in familiar zone, hab. session 11.31.42.50.91.5-1.2-1.11.1-1.61.3-1.2-0.8-0.8
Time in novel zone, hab. session 11.82.02.8-1.4-1.71.51.2-1.21.6-1.51.41.41.3
Total zone transitions, hab. session 10.10.10.30.5-0.10.30.2-0.20.2-0.30.40.60.5
Total locomotion distance, hab. session 10.10.20.40.2-0.40.40.4-0.40.4-0.50.50.60.6
Locomotion velocity, hab. session 10.10.10.30.6-0.20.30.3-0.30.2-0.30.40.40.5
Time in familiar zone, hab. session 21.51.72.71.51.6-1.3-1.21.2-1.21.5-1.1-1.0-1.1
Time in novel zone, hab. session 23.74.14.8-1.8-2.22.22.1-2.11.8-2.12.02.02.1
Total zone transitions, hab. session 20.91.22.01.11.4-1.1-1.01.1-1.31.3-0.9-0.7-0.7
Total locomotion distance, hab. session 20.10.10.90.90.3-0.10.0-0.0-0.20.1-0.00.10.1
Locomotion velocity, hab. session 20.10.10.80.90.2-0.10.1-0.1-0.00.10.10.10.1
Novel to familiar place preference ratio0.60.81.4-1.0-0.80.90.8-0.80.6-0.81.01.21.2
Novelty place preference1.01.22.0-1.0-0.91.11.0-1.00.8-1.01.31.41.4
Time in novel zone, NPP test1.21.52.2-1.2-1.11.21.0-1.11.0-1.21.31.51.4
Total zone transitions, NPP test0.50.81.91.40.9-0.9-0.60.6-1.00.8-0.8-0.7-0.7
Total locomotion distance, NPP test0.10.10.20.40.4-0.3-0.20.1-0.40.3-0.3-0.1-0.0
Locomotion velocity, NPP test0.10.10.40.60.5-0.4-0.10.1-0.40.4-0.4-0.3-0.2
Intraocular pressure0.71.13.1-1.8-1.11.00.9-1.00.8-1.00.80.90.8
Delta distance traveled before/after self-admin0.00.00.10.20.2-0.2-0.20.2-0.30.2-0.1-0.0-0.0
Delta ambulatory time before/after self-admin0.50.81.10.81.0-1.0-0.90.9-1.10.9-0.8-0.7-0.7
Parametrial fat weight0.10.21.91.40.3-0.10.2-0.20.20.1-0.0-0.2-0.1
Pavlov. Cond. lever latency0.20.30.80.50.00.40.4-0.4-0.1-0.30.60.90.8
Pavlov. Cond. magazine entry latency0.10.21.1-1.1-0.40.1-0.10.10.4-0.1-0.1-0.3-0.2
Pavlov. Cond. change in total contacts1.21.22.40.20.7-1.2-1.21.2-0.81.0-1.3-1.6-1.4
Pavlov. Cond. index score0.20.20.9-0.9-0.2-0.2-0.30.30.20.2-0.5-0.7-0.6
Pavlov. Cond. latency score0.20.20.5-0.7-0.1-0.3-0.30.30.10.3-0.5-0.7-0.6
Pavlov. Cond. lever contacts0.20.20.8-0.9-0.4-0.1-0.20.20.40.0-0.3-0.6-0.5
Pavlov. Cond. magazine entry number0.30.42.41.50.9-0.3-0.20.2-0.80.5-0.10.20.1
Pavlov. Cond. intertrial magazine entries1.21.53.00.91.0-1.2-0.91.0-0.91.1-1.4-1.7-1.7
Pavlov. Cond. lever-magazine prob. diff.0.20.31.8-1.3-0.60.10.1-0.10.6-0.2-0.2-0.4-0.4
Pavlov. Cond. response bias0.20.31.7-1.3-0.5-0.1-0.30.30.4-0.0-0.4-0.6-0.5
Pavlov. Cond. lever latency0.20.30.4-0.4-0.60.50.5-0.60.5-0.50.50.40.4
Pavlov. Cond. magazine entry latency0.10.20.4-0.00.6-0.3-0.20.4-0.30.7-0.4-0.4-0.4
Pavlov. Cond. change in total contacts0.30.70.90.20.9-0.8-0.80.9-0.71.0-0.9-0.8-0.9
Pavlov. Cond. index score0.20.30.40.20.6-0.5-0.60.6-0.50.7-0.6-0.5-0.5
Pavlov. Cond. latency score0.20.40.50.20.7-0.6-0.60.7-0.50.7-0.7-0.6-0.7
Pavlov. Cond. lever contacts0.20.30.50.50.7-0.5-0.50.6-0.60.6-0.4-0.3-0.3
Pavlov. Cond. magazine entry number0.10.10.1-0.2-0.30.20.1-0.20.1-0.30.30.30.3
Pavlov. Cond. intertrial magazine entries0.81.83.92.01.4-1.4-1.31.2-1.61.2-1.2-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.40.10.6-0.5-0.50.6-0.40.6-0.5-0.5-0.5
Pavlov. Cond. response bias0.00.10.20.20.4-0.2-0.20.3-0.20.3-0.2-0.1-0.2
Time in closed arm before self-admin1.22.02.50.71.3-1.5-1.61.5-1.41.4-1.6-1.5-1.6
Time in closed arm after self-admin1.01.11.60.20.9-1.2-1.11.1-1.11.0-1.2-1.1-1.1
Time in open arm before self-admin0.30.31.1-1.0-0.40.50.5-0.50.5-0.40.50.40.5
Time in open arm after self-admin0.91.01.3-0.2-0.91.01.0-1.01.0-1.01.11.11.1
Bone: periosteal estimation0.10.31.71.30.6-0.4-0.20.2-0.60.5-0.3-0.3-0.2
Bone: periosteal perimeter0.91.82.31.51.4-1.3-0.81.0-1.41.4-1.4-1.4-1.4
Bone: post-yield work0.10.20.30.5-0.30.40.2-0.30.3-0.40.50.50.5
Progressive ratio test 1 active lever presses1.01.72.1-1.3-1.41.41.4-1.31.5-1.41.31.11.0
Progressive ratio test 1 breakpoint1.11.92.3-1.4-1.51.51.4-1.41.5-1.41.41.21.1
Progressive ratio test 1 inactive lever presses0.20.61.0-0.8-1.00.70.7-0.81.0-0.80.70.50.4
Progressive ratio test 2 active lever presses1.11.62.0-1.3-1.41.41.3-1.31.4-1.31.21.11.0
Progressive ratio test 2 breakpoint1.41.82.2-1.4-1.41.51.4-1.41.4-1.41.31.21.1
Progressive ratio test 2 inactive lever presses0.72.23.2-1.8-1.61.51.5-1.51.6-1.51.41.31.2
Incentive Sensitization - Responses0.10.30.4-0.5-0.60.60.6-0.60.5-0.60.50.50.4
Incentive Sensitization - Breakpoint0.10.20.3-0.4-0.50.60.5-0.50.4-0.50.50.40.4
Sum of active levers in priming session hrs 5-60.10.10.30.2-0.00.20.4-0.30.3-0.20.50.50.6
Progressive ratio0.00.11.11.00.20.20.1-0.1-0.3-0.10.20.30.3
Food seeking constrained by brief footshock1.72.14.02.01.3-1.3-1.41.3-1.61.2-1.4-1.5-1.4
Seeking ratio, punishment vs. effort0.30.61.10.70.5-0.8-0.70.8-0.50.7-0.8-1.1-1.1
Retroperitoneal fat weight0.00.21.51.20.1-0.10.3-0.30.1-0.0-0.1-0.2-0.1
Reaction time number correct0.10.21.4-1.2-0.2-0.3-0.20.2-0.10.1-0.5-0.4-0.4
Reaction time mean minus median0.21.52.3-1.1-1.31.31.4-1.21.5-1.21.21.10.9
Reaction time mean minus median AUC0.32.02.9-1.6-1.51.51.6-1.41.7-1.31.31.11.0
Reaction time num false alarms0.40.71.2-1.1-0.70.71.0-1.00.5-0.70.70.90.9
Reaction time num false alarms AUC0.10.31.4-1.2-0.40.30.5-0.60.1-0.40.20.50.5
Reaction time trials correct on left0.10.21.4-1.2-0.2-0.3-0.20.2-0.10.1-0.5-0.4-0.4
Reaction time trials on left0.10.21.6-1.3-0.3-0.2-0.10.00.0-0.1-0.3-0.3-0.3
Reaction time mean2.24.86.5-2.5-2.32.22.3-2.22.3-2.12.01.91.8
Reaction time mean AUC1.84.26.2-2.5-2.12.12.2-2.12.2-1.91.91.81.7
Median of all reaction times2.74.26.6-2.6-2.22.12.1-2.12.1-2.01.91.81.7
Reaction time omissions2.33.84.9-1.6-2.01.92.2-2.21.9-2.01.91.81.8
Reaction time false alarm rate0.10.10.2-0.4-0.20.30.4-0.40.1-0.20.30.50.4
Reaction time premature initiation rate3.96.18.83.02.7-2.4-2.42.4-2.52.4-2.3-2.3-2.2
Reaction time premature initiations1.54.65.32.02.3-2.2-2.22.2-2.22.1-2.2-2.1-2.0
Std. dev. reaction times0.82.53.3-1.6-1.71.71.7-1.61.8-1.51.51.41.3
Reaction time trials completed0.10.21.6-1.3-0.3-0.2-0.10.00.0-0.1-0.3-0.3-0.3
Reaction time trials AUC0.10.21.8-1.4-0.4-0.00.1-0.10.2-0.2-0.2-0.1-0.1
Run reversals in cocaine runway, females3.94.45.5-0.9-2.12.22.4-2.32.2-2.32.22.02.0
Run reversals in cocaine runway, males0.60.61.7-1.3-0.70.70.7-0.70.6-0.60.70.80.8
Latency to leave start box in cocaine runway1.82.43.2-0.6-1.41.71.7-1.71.6-1.51.81.61.5
Latency to leave start box in cocaine runway, F2.32.93.5-1.0-1.81.91.8-1.81.9-1.81.81.61.6
Latency to leave start box in cocaine runway, M0.10.10.30.60.20.20.3-0.2-0.10.00.40.40.2
Std. dev. time between licks in bursts0.71.42.81.41.5-1.2-1.01.1-1.71.2-1.1-0.7-0.7
Total sessions with >9 infusions0.40.52.4-1.6-0.80.60.4-0.40.7-0.50.20.10.1
Short access day 1 total inactive lever presses0.51.11.6-0.2-1.31.21.1-1.21.2-1.31.10.70.7
Short access day 10 total inactive lever presses0.42.83.11.51.6-1.7-1.81.7-1.61.6-1.7-1.7-1.7
Short access day 1 total infusions0.40.82.8-1.7-1.20.90.6-0.70.9-0.80.30.20.3
Short access day 10 total infusions0.30.41.1-1.1-0.80.70.6-0.60.8-0.60.50.30.2
Short access total infusions0.60.81.7-1.3-1.11.00.9-0.91.0-0.90.70.50.5
Short access day 1 locomotion0.81.43.9-2.0-1.51.31.0-1.11.2-1.10.80.60.7
Short access day 10 total locomotion0.00.21.5-1.2-0.20.10.2-0.20.1-0.10.10.20.2
Short access total locomotion0.50.83.1-1.7-1.00.80.8-0.80.9-0.70.50.50.6
One hour access (0.3 mA shock)0.81.01.1-1.1-1.01.01.0-1.01.0-1.01.01.00.9
Compulsive drug intake1.01.52.10.11.2-1.4-1.31.4-1.21.4-1.4-1.2-1.2
One hour access (shock baseline)0.82.22.6-1.0-1.51.61.6-1.61.4-1.51.61.51.3
Social response proportion0.91.21.8-0.3-0.91.11.4-1.31.1-1.01.11.11.1
Social responses0.10.20.50.40.5-0.00.3-0.2-0.40.20.20.70.7
Social time1.01.52.00.71.4-1.3-1.31.3-1.31.4-1.2-1.1-1.1
Soleus weight0.00.10.4-0.2-0.00.30.4-0.30.1-0.20.40.60.6
Bone: stiffness0.71.31.70.4-1.11.21.2-1.21.3-1.31.31.01.1
Tibialis anterior weight0.00.00.3-0.6-0.00.10.2-0.10.00.1-0.1-0.00.0
Time to tail flick, vehicle, before self-admin0.10.10.60.70.3-0.2-0.20.2-0.40.2-0.1-0.00.1
Time to tail flick, vehicle, after self-admin0.10.20.70.90.10.10.2-0.3-0.1-0.20.50.70.7
Time to tail flick, test, before self-admin3.54.15.2-1.7-2.22.22.1-2.12.3-2.11.91.71.8
Time to tail flick, test, after self-admin0.10.10.20.2-0.00.10.2-0.20.2-0.10.20.30.5
Delta time to tail flick, vehicle, before/after SA0.00.00.10.2-0.20.10.2-0.20.2-0.20.20.20.2
Delta time to tail flick, test, before/after SA0.60.71.00.41.0-1.0-0.80.9-1.01.0-0.9-0.6-0.5
Tibia length0.00.10.30.1-0.40.0-0.10.10.5-0.3-0.0-0.5-0.4
Ambulatory time before self-admin0.51.62.4-1.6-1.51.41.2-1.21.4-1.31.10.91.0
Ambulatory time after self-admin0.20.30.5-0.7-0.70.70.5-0.60.6-0.60.50.50.5
Bone: tissue strength0.30.30.6-0.8-0.70.40.6-0.60.7-0.50.1-0.1-0.0
Total heroin consumption0.20.30.6-0.2-0.30.40.6-0.60.4-0.50.60.80.7
Bone: trabecular number3.46.39.32.12.5-2.6-3.12.9-2.42.5-2.3-2.3-2.3
Bone: trabecular spacing2.63.85.1-1.8-2.02.02.3-2.21.8-1.91.81.81.8
Bone: trabecular thickness0.10.20.70.80.3-0.4-0.60.5-0.20.3-0.2-0.2-0.2
Bone: trabecular tissue density3.76.57.2-1.8-2.62.62.6-2.62.7-2.72.62.52.6
Water consumed over 24 hours0.10.20.60.80.6-0.3-0.40.5-0.50.4-0.10.10.1
Number of responses in last shaping day0.30.40.6-0.80.2-0.5-0.60.6-0.30.5-0.8-0.7-0.7