Hub : Genes

Erich2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr3_55328486_55332420 0.07 0.07 6.1e-03 0 0.01 0.02 0.01 1.0e-01 7.7e-03 6.1e-03 2.4e-02
2 pVTA intron excision ratio chr3_55328486_55337555 0.06 0.04 1.3e-03 0.01 0.05 0.05 0.03 8.7e-02 4.7e-03 2.9e-03 1.7e-02
3 Brain alternative TSS NM_001024311.1 0.02 0.02 6.6e-03 0.02 0.01 0.01 0.01 6.5e-03 2.1e-02 2.3e-02 1.2e-02
4 Brain alternative TSS XM_006234340.4 0.02 0.02 5.7e-03 0.02 0.01 0.02 0.02 4.6e-03 1.3e-02 1.1e-02 8.1e-03
5 Brain alternative TSS NM_001024311.1 0.03 0.02 1.4e-03 0.03 0.02 0.02 0.03 4.2e-04 3.0e-03 3.6e-03 1.9e-03
6 Brain alternative TSS XM_006234340.4 0.03 0.02 1.1e-03 0.04 0.03 0.03 0.03 2.1e-04 1.4e-03 1.3e-03 8.6e-04
7 Adipose gene expression Erich2 0.04 0.03 3.8e-06 0.05 0.05 0.04 0.05 4.7e-06 4.3e-06 8.2e-06 4.9e-06
8 Brain mRNA stability Erich2 0.04 0.03 1.6e-05 0.04 0.05 0.04 0.05 5.2e-05 1.6e-05 6.1e-05 3.5e-05
9 Brain gene expression Erich2 0.04 0.03 7.3e-05 0.05 0.05 0.05 0.05 1.3e-05 2.2e-05 2.8e-05 1.3e-05
10 NAcc alternative TSS XM_006234340.4 0.05 0.04 3.4e-05 0.04 0.03 0.03 0.03 1.5e-05 8.6e-05 3.1e-04 9.1e-05
11 NAcc alternative TSS XM_006234340.4 0.04 0.03 3.9e-05 0.04 0.03 0.03 0.03 1.6e-05 8.7e-05 2.7e-04 9.7e-05
12 pVTA alternative TSS XM_006234340.4 0.06 0.04 4.6e-03 0.07 0.03 0.05 0.05 6.1e-04 1.9e-02 2.3e-03 2.3e-03
13 pVTA alternative TSS XM_006234340.4 0.05 0.04 9.5e-03 0.06 0.02 0.04 0.04 1.4e-03 4.4e-02 6.0e-03 6.8e-03
14 PL alternative TSS XM_006234340.4 0.03 0.02 4.5e-04 0.03 0.02 0.03 0.02 3.0e-04 1.1e-03 6.2e-04 1.6e-03
15 PL alternative TSS XM_006234340.4 0.03 0.02 8.3e-04 0.03 0.02 0.03 0.03 1.1e-04 1.6e-03 4.9e-04 4.6e-04
16 IL gene expression Erich2 0.3 0.19 3.1e-03 0.02 0.06 0.01 0.03 1.1e-01 1.4e-02 1.6e-01 7.0e-02
17 NAcc intron excision ratio chr3_55328486_55337555 0.05 0.03 1.3e-06 0.05 0.04 0.04 0.04 4.2e-06 1.4e-05 1.5e-05 1.2e-05
18 NAcc gene expression Erich2 0.04 0.03 5.2e-06 0.03 0.03 0.03 0.03 1.4e-04 1.7e-04 5.8e-04 4.6e-04
19 Brain isoform ratio NM_001024311.1 0.02 0.02 2.9e-03 0 0.02 0.01 0.01 1.2e-01 1.0e-02 3.1e-02 5.0e-02
20 Brain intron excision ratio chr3_55328486_55337555 0.02 0.02 4.2e-03 0.02 0.01 0.01 0.01 4.5e-03 2.2e-02 4.5e-02 1.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.00.00.3-0.6-0.0-0.00.0-0.00.0-0.10.2-0.1-0.0-0.0-0.2-0.2-0.2-0.2-0.1-0.10.00.20.1
Area under the delay curve3.03.25.31.1-2.31.9-1.91.9-1.91.9-1.91.8-1.7-1.7-1.6-1.6-1.7-1.71.3-1.6-1.7-2.3-1.7
BMI with tail0.51.72.80.3-1.21.4-1.41.4-1.41.6-1.61.4-1.7-1.7-1.0-1.0-1.0-1.01.5-1.0-1.0-1.4-1.0
BMI without tail0.10.30.60.8-0.50.3-0.30.3-0.30.6-0.60.4-0.3-0.3-0.7-0.7-0.6-0.60.5-0.6-0.6-0.6-0.5
Body weight1.98.09.51.6-3.02.8-2.82.8-2.82.9-2.92.7-3.1-3.1-3.0-3.0-3.0-3.02.7-2.9-2.9-2.8-2.7
Weight adjusted by age0.91.04.02.0-1.20.8-0.80.8-0.80.8-0.90.9-1.0-1.0-0.6-0.6-0.8-0.80.9-0.8-1.0-1.1-1.1
Bone surface0.91.53.11.8-1.21.4-1.41.4-1.40.7-0.71.2-0.5-0.5-1.4-1.4-1.4-1.41.2-1.4-1.3-0.5-1.2
Bone volume0.71.21.71.1-1.11.2-1.21.2-1.20.8-0.81.1-0.7-0.7-1.3-1.3-1.3-1.31.1-1.3-1.1-0.6-1.0
Breakpoint value in progressive ratio session0.20.21.0-1.0-0.40.4-0.40.4-0.40.8-0.70.4-0.4-0.4-0.6-0.6-0.5-0.50.3-0.2-0.1-0.5-0.2
Number of licking bursts0.20.21.1-1.1-0.0-0.60.6-0.60.6-0.20.2-0.6-0.1-0.1-0.2-0.2-0.3-0.3-0.4-0.2-0.0-0.10.3
Context. condit. distance diff. score5.26.310.8-3.33.1-2.52.5-2.52.5-2.32.5-2.52.02.02.42.42.42.4-2.32.42.23.02.3
Locomotion velocity, session 12.83.04.1-0.91.5-2.02.0-2.02.0-2.01.9-1.91.41.41.71.71.71.7-2.01.71.61.51.9
Locomotion distance, session 13.74.76.8-0.92.3-2.32.3-2.32.3-2.62.6-2.32.12.12.02.01.91.9-2.21.92.02.52.3
Locomotion velocity, session 20.30.31.0-0.80.1-0.00.0-0.00.0-0.20.1-0.1-1.0-1.00.80.80.70.7-0.20.70.50.00.3
Locomotion distance, session 20.00.00.20.3-0.00.1-0.10.1-0.1-0.20.20.1-0.5-0.50.10.1-0.1-0.10.20.0-0.30.30.1
Locomotion velocity, session 30.60.61.0-0.80.8-0.80.8-0.80.8-0.90.9-0.90.10.10.90.90.80.8-0.80.80.70.91.0
Locomotion distance, session 30.10.21.61.30.2-0.00.0-0.00.0-0.40.3-0.20.30.30.30.30.30.3-0.00.5-0.00.40.2
Stereotopy head waving bouts, day 30.60.81.3-0.50.8-0.90.9-0.90.9-0.90.9-1.10.80.80.90.90.70.7-1.10.70.80.61.1
Stereotopy head waving duration, day 30.10.10.7-0.80.4-0.30.3-0.30.3-0.20.2-0.40.10.10.30.30.20.2-0.40.00.30.10.4
Locomotion velocity, session 71.31.42.9-0.5-1.00.9-0.90.9-0.91.3-1.31.0-1.7-1.7-1.3-1.3-1.3-1.31.1-1.2-1.2-1.1-1.2
Locomotion distance, session 71.21.53.4-0.9-0.91.0-1.01.0-1.01.4-1.40.9-1.9-1.9-1.3-1.3-1.2-1.21.1-1.1-1.1-1.2-1.1
Stereotopy head waving bouts, day 70.30.43.71.90.00.4-0.40.4-0.4-0.30.20.30.70.70.60.60.60.60.20.40.10.20.1
Stereotopy head waving duration, day 70.50.65.52.3-0.80.9-0.90.9-0.90.4-0.51.0-0.0-0.0-0.1-0.1-0.1-0.10.8-0.2-0.6-0.5-0.6
Locomotion velocity, session 81.01.23.2-1.81.3-1.11.1-1.11.1-1.11.1-1.1-0.2-0.21.31.31.11.1-0.91.10.81.41.0
Locomotion distance, session 82.74.09.3-3.12.6-2.02.0-2.02.0-1.82.0-2.01.01.02.02.01.91.9-1.72.01.62.42.0
Degree of sensitization distance0.60.63.6-1.9-0.20.1-0.10.1-0.10.8-0.80.3-1.0-1.0-0.9-0.9-0.9-0.90.5-1.0-0.4-0.6-0.6
Degree of sensitization stereotypy0.40.52.81.7-0.41.0-1.01.0-1.00.2-0.21.0-0.1-0.10.50.50.50.50.70.4-0.1-0.1-0.3
Conditioned locomotion1.21.42.5-0.71.4-1.21.2-1.21.2-1.21.3-1.11.61.61.21.21.11.1-0.91.10.91.51.0
Cocaine response after cond. corrected0.80.91.90.1-0.61.4-1.41.4-1.41.1-1.01.1-1.4-1.4-0.4-0.4-0.4-0.41.1-0.4-0.6-0.6-0.7
Cocaine response after cond. not corrected1.11.22.60.4-0.71.6-1.61.6-1.61.2-1.11.3-1.5-1.5-0.4-0.4-0.3-0.31.4-0.4-0.6-0.7-0.9
Cocaine response before conditioning0.00.10.10.10.3-0.10.1-0.10.1-0.30.3-0.20.20.20.30.30.30.3-0.00.30.40.30.1
Saline control response0.91.28.5-2.9-0.50.9-0.90.9-0.91.4-1.31.0-1.5-1.5-0.4-0.4-0.4-0.40.9-0.5-0.7-0.9-0.8
Bone: connectivity density0.10.10.4-0.60.2-0.40.4-0.40.4-0.40.4-0.5-0.1-0.10.10.10.10.1-0.40.20.20.30.1
Bone: cortical apparent density0.40.52.11.40.2-0.30.3-0.30.3-0.70.7-0.51.41.40.40.40.50.5-0.70.70.30.60.4
Bone: cortical area3.14.77.32.7-2.22.5-2.52.5-2.51.9-1.92.4-1.2-1.2-2.3-2.3-2.2-2.22.2-2.0-2.1-1.6-2.1
Bone: cortical porosity0.00.00.1-0.30.1-0.00.0-0.00.0-0.10.10.00.00.00.00.00.00.00.1-0.10.20.20.1
Bone: cortical porosity0.00.00.10.40.00.3-0.30.3-0.3-0.10.10.20.30.3-0.2-0.2-0.1-0.10.3-0.30.10.3-0.0
Bone: cortical thickness1.42.34.52.1-1.51.7-1.71.7-1.71.3-1.21.8-0.6-0.6-1.7-1.7-1.6-1.61.5-1.3-1.5-0.9-1.4
Bone: cortical thickness0.20.21.1-1.1-0.00.4-0.40.4-0.40.5-0.40.4-0.6-0.6-0.4-0.4-0.3-0.30.4-0.2-0.30.1-0.4
Bone: cortical tissue density0.60.82.61.20.4-0.60.6-0.60.6-0.90.9-0.81.61.60.60.60.80.8-0.90.90.60.80.6
Condit. Reinf. active minus inactive responses0.70.83.92.0-1.20.8-0.80.8-0.80.6-0.61.0-0.7-0.7-0.6-0.6-0.6-0.60.9-0.6-0.9-0.8-0.9
Condit. Reinf. active-inactive response ratio1.31.43.51.9-1.71.2-1.21.2-1.21.1-1.11.4-1.1-1.1-0.9-0.9-0.8-0.81.1-0.8-1.2-1.4-1.3
Condit. Reinf. active responses0.20.20.40.40.4-0.40.4-0.40.4-0.60.5-0.30.20.20.60.60.60.6-0.20.60.20.60.3
Condit. Reinf. inactive responses3.64.37.4-2.12.7-2.12.1-2.12.1-2.12.2-2.21.71.72.12.12.02.0-1.81.92.02.62.1
Incentive salience index mean0.60.75.52.3-1.20.8-0.80.8-0.80.3-0.40.9-0.4-0.4-0.4-0.4-0.4-0.40.5-0.3-0.8-0.8-0.6
Condit. Reinf. lever presses0.10.11.21.1-0.30.1-0.10.1-0.1-0.30.20.10.30.30.10.10.20.2-0.30.30.1-0.00.2
Condit. Reinf. active minus inactive responses0.20.22.9-1.70.40.2-0.20.2-0.20.4-0.30.20.10.1-0.1-0.1-0.1-0.10.4-0.00.10.3-0.1
Condit. Reinf. active-inactive response ratio0.40.51.20.2-0.20.8-0.80.8-0.80.7-0.60.8-0.2-0.2-0.7-0.7-0.7-0.71.1-0.8-0.7-0.1-0.8
Condit. Reinf. active responses0.20.33.6-1.90.20.3-0.30.3-0.30.6-0.50.3-0.3-0.3-0.4-0.4-0.4-0.40.5-0.3-0.1-0.1-0.3
Condit. Reinf. inactive responses0.20.23.0-1.70.1-0.10.1-0.10.10.3-0.2-0.2-0.6-0.6-0.1-0.1-0.1-0.1-0.2-0.10.1-0.20.1
Condit. Reinf. lever presses0.20.22.7-1.70.7-0.20.2-0.20.2-0.10.2-0.30.20.20.30.30.30.3-0.20.40.40.50.3
Condit. Reinf. lever reinforcers received0.20.33.7-1.90.10.3-0.30.3-0.30.7-0.60.3-0.4-0.4-0.4-0.4-0.4-0.40.5-0.3-0.2-0.2-0.3
Conditioned reinforcement - actives0.10.10.40.70.40.1-0.10.1-0.1-0.20.20.10.20.20.30.30.60.60.10.20.20.2-0.0
Conditioned reinforcement - inactives0.00.10.40.4-0.30.0-0.00.0-0.00.1-0.20.0-0.2-0.2-0.2-0.20.30.3-0.1-0.0-0.0-0.7-0.1
Conditioned locomotion0.30.31.61.3-0.60.6-0.60.6-0.60.5-0.50.6-0.4-0.4-0.5-0.5-0.3-0.30.4-0.5-0.6-0.7-0.6
Patch foraging indifference point 0 sec0.10.10.70.8-0.60.2-0.20.2-0.20.1-0.20.3-0.1-0.1-0.3-0.3-0.3-0.30.1-0.2-0.4-0.5-0.3
Patch foraging indifference point AUC1.11.32.91.20.9-1.11.1-1.11.1-1.31.2-1.11.71.71.01.01.01.0-1.00.90.90.80.9
Delay disc. indifference point, 0s delay7.27.910.61.0-3.23.0-3.03.0-3.03.3-3.23.0-3.1-3.1-2.3-2.3-2.4-2.42.5-2.5-2.8-3.2-2.8
Delay disc. indifference point, 16s delay0.10.10.5-0.1-0.60.1-0.10.1-0.10.3-0.30.1-0.1-0.1-0.2-0.2-0.3-0.3-0.0-0.3-0.2-0.7-0.3
Delay disc. indifference point, 2s delay6.06.69.62.1-3.12.8-2.82.8-2.82.5-2.52.7-2.6-2.6-2.3-2.3-2.5-2.52.2-2.5-2.5-2.7-2.5
Delay disc. indifference point, 24s delay1.21.22.0-0.50.9-1.01.0-1.01.0-1.41.4-1.01.11.11.11.11.01.0-1.31.01.11.11.2
Delay disc. indifference point, 4s delay11.912.618.72.2-4.33.7-3.73.7-3.73.5-3.63.6-3.4-3.4-3.6-3.6-3.7-3.72.9-3.3-3.6-3.9-3.4
Delay disc. indifference point, 8s delay3.23.35.11.2-2.22.0-2.02.0-2.02.0-2.01.9-1.8-1.8-1.5-1.5-1.7-1.71.5-1.7-1.8-2.2-1.7
Indifference point function ln k0.10.10.3-0.3-0.20.3-0.30.3-0.30.3-0.30.3-0.5-0.5-0.3-0.3-0.3-0.30.3-0.2-0.4-0.1-0.1
Indifference point function log k0.10.10.3-0.3-0.20.3-0.30.3-0.30.3-0.30.3-0.5-0.5-0.3-0.3-0.3-0.30.3-0.2-0.4-0.1-0.1
Patch foraging total patch changes 0 sec0.00.10.20.3-0.0-0.30.3-0.30.3-0.30.3-0.20.40.40.20.20.20.2-0.30.20.0-0.00.2
Patch foraging total patch changes 12 sec0.60.71.30.70.4-0.90.9-0.90.9-0.90.8-0.81.21.20.90.90.80.8-1.10.80.60.30.8
Patch foraging total patch changes 18 sec0.81.01.90.70.8-1.21.2-1.21.2-1.21.0-1.11.41.40.80.80.80.8-1.00.70.90.60.9
Patch foraging total patch changes 24 sec0.00.10.20.50.30.1-0.10.1-0.1-0.10.10.10.30.30.10.1-0.0-0.00.4-0.0-0.20.4-0.3
Patch foraging total patch changes 6 sec0.00.10.60.8-0.40.0-0.00.0-0.0-0.1-0.00.00.20.2-0.1-0.1-0.1-0.1-0.2-0.1-0.2-0.5-0.0
Patch foraging time to switch 0 sec0.20.33.1-1.8-0.00.0-0.00.0-0.00.6-0.5-0.0-1.1-1.1-0.2-0.2-0.1-0.10.2-0.0-0.0-0.3-0.1
Patch foraging water rate 0 sec0.20.22.01.40.1-0.20.2-0.20.2-0.60.6-0.20.90.90.10.10.10.1-0.2-0.1-0.00.50.3
Patch foraging water rate 12 sec2.03.14.02.0-1.81.9-1.91.9-1.91.5-1.61.9-1.7-1.7-1.8-1.8-1.8-1.81.6-1.8-1.7-1.5-1.6
Patch foraging water rate 18 sec0.40.61.1-0.0-0.71.1-1.11.1-1.10.7-0.61.0-0.9-0.9-0.6-0.6-0.5-0.50.5-0.5-0.5-0.4-0.5
Patch foraging water rate 24 sec0.20.31.0-0.8-0.50.5-0.50.5-0.50.5-0.40.5-1.0-1.0-0.4-0.4-0.3-0.30.3-0.3-0.4-0.3-0.1
Patch foraging water rate 6 sec0.10.10.20.5-0.30.3-0.30.3-0.30.0-0.00.4-0.2-0.2-0.2-0.2-0.3-0.30.2-0.4-0.10.00.1
Seeking ratio, delayed vs. immediate footshock0.60.71.10.5-1.00.9-0.90.9-0.90.8-0.80.9-1.0-1.0-0.7-0.7-0.8-0.80.7-1.0-0.9-0.8-0.9
Distance traveled before self-admin2.72.93.90.6-1.81.8-1.81.8-1.81.7-1.71.8-2.0-2.0-1.8-1.8-1.7-1.71.8-1.5-1.5-1.6-1.6
Distance traveled after self-admin2.52.84.70.7-2.21.7-1.71.7-1.71.8-1.81.7-1.8-1.8-1.6-1.6-1.6-1.61.5-1.5-1.5-2.0-1.5
Extensor digitorum longus weight0.00.21.41.2-0.70.4-0.40.4-0.4-0.0-0.00.10.50.5-0.2-0.2-0.2-0.2-0.1-0.1-0.0-0.3-0.0
Bone: elastic displacement0.40.42.3-1.50.5-0.60.6-0.60.6-0.30.4-0.60.40.40.70.70.70.7-0.80.70.80.20.6
Bone: elastic work0.40.50.70.0-0.70.8-0.80.8-0.80.9-0.80.8-0.5-0.5-0.8-0.8-0.6-0.60.6-0.5-0.5-0.6-0.7
Bone: endosteal estimation0.92.04.3-0.4-1.01.5-1.51.5-1.51.5-1.51.4-2.1-2.1-1.0-1.0-1.2-1.21.8-1.3-1.4-1.2-1.6
Bone: endosteal perimeter0.61.22.10.3-0.81.3-1.31.3-1.31.2-1.21.2-1.3-1.3-0.7-0.7-0.9-0.91.4-0.9-1.0-0.9-1.2
Epididymis fat weight0.30.71.2-0.51.0-0.80.8-0.80.8-0.60.6-0.80.30.31.11.11.01.0-0.61.00.80.80.8
Delta time in closed arm before/after self-admin0.00.00.1-0.0-0.10.1-0.10.1-0.10.3-0.20.10.10.10.00.0-0.0-0.0-0.0-0.0-0.0-0.4-0.2
Delta time in open arm before/after self-admin0.90.81.61.3-1.10.8-0.80.8-0.80.7-0.70.8-0.7-0.7-1.2-1.2-1.1-1.10.7-1.0-1.1-0.8-0.8
Diff in mean of infusions in LGA sessions0.30.30.6-0.50.5-0.60.6-0.60.6-0.40.5-0.60.80.80.50.50.60.6-0.80.50.60.30.5
Delay discount exponential model param2.02.13.7-1.01.9-1.61.6-1.61.6-1.51.6-1.51.31.31.31.31.41.4-1.01.31.41.91.3
Extinction: sum of active levers before priming3.93.95.31.2-2.31.9-1.91.9-1.92.1-2.11.9-2.1-2.1-2.1-2.1-2.0-2.01.7-1.9-1.8-2.2-1.8
Active lever presses in extinction session 60.30.30.8-0.20.4-0.60.6-0.60.6-0.50.5-0.60.70.70.20.20.20.2-0.60.80.90.50.7
Bone: final force4.16.58.51.1-2.52.6-2.62.6-2.62.7-2.62.6-2.3-2.3-2.9-2.9-2.8-2.82.6-2.7-2.8-2.2-2.6
Bone: final moment4.26.88.31.3-2.52.7-2.72.7-2.72.7-2.72.7-2.3-2.3-2.9-2.9-2.8-2.82.7-2.7-2.8-2.2-2.7
Food consumed during 24 hour testing period0.10.11.0-1.00.2-0.50.5-0.50.5-0.10.1-0.50.40.4-0.1-0.1-0.0-0.0-0.3-0.0-0.1-0.1-0.0
Glucose0.30.50.80.4-0.80.7-0.70.7-0.70.6-0.70.7-0.9-0.9-0.7-0.7-0.7-0.70.4-0.8-0.7-0.9-0.5
Heart weight0.10.20.4-0.20.00.4-0.40.4-0.40.6-0.50.5-0.4-0.4-0.5-0.5-0.5-0.50.7-0.4-0.3-0.0-0.1
Delay discount hyperbolic model param4.04.26.6-1.32.6-2.22.2-2.22.2-2.12.2-2.22.02.01.81.82.02.0-1.61.92.02.51.9
Intermittent access intake day 1-15 change0.00.00.20.4-0.40.2-0.20.2-0.20.1-0.20.2-0.1-0.10.10.10.10.1-0.10.10.0-0.4-0.1
Intermittent access intake escalation0.10.10.30.2-0.50.4-0.40.4-0.40.4-0.40.4-0.3-0.3-0.1-0.1-0.2-0.20.1-0.1-0.1-0.5-0.2
Intermittent access intake escalation 20.00.00.2-0.4-0.0-0.10.1-0.10.10.00.0-0.10.10.10.40.40.20.2-0.30.30.2-0.10.2
Intermitt. access day 1 inactive lever presses0.10.10.20.00.2-0.30.3-0.30.3-0.50.5-0.30.20.20.10.10.30.3-0.40.20.20.50.2
Intermitt. access day 15 inactive lever presses0.50.60.8-0.30.9-0.80.8-0.80.8-0.60.6-0.80.70.70.90.90.90.9-0.70.80.80.70.7
Intermitt. access escalation Index0.20.20.50.10.6-0.50.5-0.50.5-0.70.6-0.50.40.40.20.20.30.3-0.20.50.50.70.5
Intermittent access day 1 total infusions0.00.00.1-0.30.10.2-0.20.2-0.20.4-0.30.2-0.3-0.30.00.00.10.10.3-0.2-0.2-0.1-0.2
Intermittent access day 15 total infusions0.30.30.60.2-0.50.6-0.60.6-0.60.8-0.80.6-0.6-0.6-0.3-0.3-0.2-0.20.5-0.4-0.5-0.8-0.4
Intermittent access terminal intake (last 3 days)0.30.30.70.1-0.50.6-0.60.6-0.60.8-0.80.6-0.5-0.5-0.3-0.3-0.3-0.30.6-0.5-0.5-0.8-0.5
Intermittent access total infusions0.20.20.50.2-0.40.5-0.50.5-0.50.7-0.70.5-0.5-0.5-0.3-0.3-0.2-0.20.6-0.4-0.5-0.7-0.4
Intermittent access day 1 locomotion0.00.00.2-0.50.30.0-0.00.0-0.00.2-0.10.00.10.10.10.10.10.10.0-0.0-0.00.10.1
Intermittent access day 15 total locomotion0.10.11.0-1.00.3-0.00.0-0.00.00.2-0.1-0.00.00.00.40.40.50.5-0.20.20.2-0.00.1
Intermittent access total locomotion0.10.10.20.0-0.10.3-0.30.3-0.30.4-0.40.3-0.1-0.1-0.2-0.2-0.1-0.10.1-0.3-0.3-0.4-0.2
Intermittent access standard deviation1.41.52.50.1-1.21.3-1.31.3-1.31.6-1.61.3-1.4-1.4-0.8-0.8-0.7-0.71.2-1.1-1.1-1.5-1.2
Left kidney weight0.72.13.2-0.4-1.21.5-1.51.5-1.51.5-1.41.4-1.8-1.8-1.4-1.4-1.5-1.51.6-1.5-1.5-1.1-1.1
Right kidney weight0.61.72.70.8-1.21.2-1.21.2-1.21.2-1.21.2-1.2-1.2-1.6-1.6-1.5-1.51.3-1.5-1.5-1.0-1.0
Cocaine induced anxiety1.61.93.11.4-1.81.3-1.31.3-1.31.3-1.41.3-1.3-1.3-1.2-1.2-1.4-1.41.0-1.4-1.4-1.8-1.2
Post-drug Anxiety0.20.20.9-1.00.2-0.50.5-0.50.5-0.20.2-0.50.30.30.30.30.30.3-0.50.50.5-0.10.6
Baseline Anxiety4.04.35.9-2.42.2-2.12.1-2.12.1-1.91.9-2.12.02.01.91.92.22.2-1.92.22.22.02.0
Tail length0.10.21.01.0-0.5-0.10.1-0.10.1-0.10.1-0.10.10.1-0.7-0.7-0.7-0.7-0.1-0.6-0.5-0.3-0.1
Length with tail1.55.48.41.8-2.72.0-2.02.0-2.02.0-2.02.0-2.1-2.1-2.9-2.9-2.8-2.81.9-2.7-2.5-2.1-2.2
Length without tail1.43.03.70.8-1.91.8-1.81.8-1.81.7-1.71.8-1.9-1.9-1.9-1.9-1.9-1.91.6-1.9-1.6-1.5-1.6
Times rat made contact with spout0.20.22.9-1.70.3-0.50.5-0.50.5-0.10.1-0.5-0.3-0.3-0.2-0.2-0.2-0.2-0.5-0.20.00.00.2
Lifetime Intake0.20.20.40.4-0.30.4-0.40.4-0.40.6-0.60.4-0.5-0.5-0.2-0.2-0.1-0.10.5-0.3-0.3-0.6-0.4
Liver weight, left1.93.04.30.9-1.42.0-2.02.0-2.01.9-1.81.9-1.7-1.7-1.6-1.6-1.6-1.62.1-1.6-1.6-1.3-1.8
Liver weight, right0.30.50.8-0.7-0.70.6-0.60.6-0.60.9-0.90.6-0.8-0.8-0.7-0.7-0.6-0.60.6-0.5-0.3-0.8-0.5
Locomotor activity0.30.51.00.30.3-0.90.9-0.90.9-1.00.9-0.80.60.60.70.70.70.7-0.90.60.70.40.7
Locomotor testing distance0.40.71.0-1.00.7-1.01.0-1.01.0-0.90.8-0.90.20.20.80.80.80.8-0.90.70.70.60.8
Locomotor testing rearing0.10.11.1-1.0-0.00.1-0.10.1-0.10.2-0.10.2-0.8-0.8-0.1-0.1-0.1-0.10.2-0.2-0.3-0.0-0.2
Locomotion in novel chamber5.16.38.91.4-3.02.7-2.72.7-2.72.5-2.62.5-2.7-2.7-2.5-2.5-2.4-2.42.2-2.4-2.3-2.8-2.4
Locomotion in novel chamber post-restriction2.32.73.91.4-1.41.6-1.61.6-1.61.3-1.21.7-1.6-1.6-1.9-1.9-1.9-1.91.9-2.0-1.9-0.7-1.6
Fecal boli incidents, locomotor time 10.30.30.9-0.30.4-0.50.5-0.50.5-0.50.4-0.50.40.40.60.60.60.6-0.70.90.90.20.6
Change in fecal boli incidents, locomotor task0.30.30.70.50.6-0.40.4-0.40.4-0.80.7-0.40.30.30.80.80.70.7-0.20.60.50.80.4
Time >=10cm from walls, locomotor time 10.40.40.70.5-0.60.7-0.70.7-0.70.4-0.40.7-0.7-0.7-0.8-0.8-0.8-0.80.7-0.6-0.6-0.3-0.6
Bouts of movement, locomotor time 10.10.10.50.7-0.20.2-0.20.2-0.20.2-0.30.2-0.2-0.20.10.1-0.0-0.00.3-0.3-0.4-0.3-0.2
Total resting periods, locomotor time 10.20.20.5-0.00.5-0.50.5-0.50.5-0.40.4-0.50.40.40.70.70.60.6-0.40.40.30.30.4
Rest time, locomotor task time 12.32.54.1-0.11.6-1.61.6-1.61.6-1.61.6-1.61.51.52.02.01.91.9-1.51.41.41.31.5
Distance moved, locomotor task time 14.95.37.6-0.1-2.22.3-2.32.3-2.32.5-2.42.2-2.2-2.2-2.7-2.7-2.6-2.62.2-2.4-2.3-2.0-2.3
Vertical activity count, locomotor time 14.95.26.50.4-2.42.3-2.32.3-2.32.5-2.52.2-2.2-2.2-2.5-2.5-2.4-2.42.2-2.3-2.3-2.3-2.2
Time >=10cm from walls, locomotor time 22.62.74.20.5-1.51.8-1.81.8-1.82.1-2.01.8-1.8-1.8-1.4-1.4-1.4-1.41.8-1.3-1.5-1.8-1.7
Bouts of movement, locomotor time 23.33.64.70.01.6-2.02.0-2.02.0-2.22.1-2.01.91.91.91.92.02.0-2.11.91.91.51.9
Total resting periods, locomotor time 25.05.47.0-0.22.1-2.42.4-2.42.4-2.62.5-2.52.42.42.32.32.32.3-2.62.32.41.92.4
Rest time, locomotor task time 23.03.54.7-0.61.6-1.91.9-1.91.9-2.22.1-1.81.81.82.02.02.02.0-2.02.01.81.62.0
Distance moved, locomotor task time 28.59.913.20.7-2.93.2-3.23.2-3.23.6-3.53.1-2.9-2.9-3.3-3.3-3.3-3.33.2-3.4-3.3-2.9-3.3
Vertical activity count, locomotor time 28.08.711.01.3-3.03.0-3.03.0-3.03.3-3.33.0-2.8-2.8-2.9-2.9-2.9-2.92.9-3.2-3.1-3.0-3.1
Light reinforcement 10.30.51.0-0.3-0.70.7-0.70.7-0.70.9-1.00.8-0.9-0.9-0.5-0.5-0.6-0.60.9-0.6-0.6-0.9-0.8
Light reinforcement 21.52.13.10.2-1.71.4-1.41.4-1.41.7-1.71.5-1.4-1.4-1.3-1.3-1.4-1.41.4-1.3-1.3-1.8-1.5
Bone: marrow area1.02.24.4-0.2-1.11.6-1.61.6-1.61.6-1.61.4-2.1-2.1-1.1-1.1-1.2-1.21.8-1.4-1.4-1.3-1.6
Bone: maximum diameter1.01.86.62.6-1.31.6-1.61.6-1.61.1-1.11.6-0.6-0.6-1.2-1.2-1.2-1.21.5-1.1-1.1-0.9-1.4
Bone: maximum force2.03.54.90.7-1.52.1-2.12.1-2.11.9-1.82.0-1.7-1.7-2.0-2.0-2.0-2.02.2-1.9-2.1-1.1-1.9
Bone: maximum moment2.13.75.30.9-1.52.2-2.22.2-2.21.9-1.82.1-1.7-1.7-1.9-1.9-2.0-2.02.3-1.8-2.1-1.2-2.0
Mean time between licks in bursts0.10.10.5-0.1-0.10.2-0.20.2-0.20.2-0.30.2-0.3-0.3-0.3-0.3-0.3-0.30.7-0.4-0.5-0.2-0.6
Mean num. licks in bursts0.10.10.3-0.20.50.0-0.00.0-0.0-0.20.2-0.0-0.1-0.10.50.50.50.5-0.20.40.40.30.1
Cd content in liver0.30.41.41.2-0.10.5-0.50.5-0.50.4-0.30.4-0.2-0.2-0.7-0.7-0.8-0.80.8-0.8-0.60.1-0.6
Co content in liver5.05.910.53.2-2.62.5-2.52.5-2.52.2-2.22.5-2.2-2.2-2.4-2.4-2.3-2.32.4-2.3-2.4-2.2-2.5
Cu content in liver0.50.71.11.00.7-0.40.4-0.40.4-1.00.9-0.30.80.81.01.01.11.1-0.41.00.91.00.7
Fe content in liver1.01.22.60.71.0-0.90.9-0.90.9-1.11.1-0.91.61.61.11.11.11.1-1.01.10.91.01.0
K content in liver0.20.22.2-1.50.40.0-0.00.0-0.00.2-0.20.2-0.8-0.80.50.50.40.40.30.30.30.1-0.0
Mg content in liver1.01.01.8-1.01.3-1.01.0-1.01.0-0.90.9-0.90.50.51.21.21.11.1-0.81.11.21.11.0
Mn content in liver0.20.20.5-0.20.3-0.50.5-0.50.5-0.60.6-0.40.20.20.50.50.50.5-0.50.60.70.30.5
Na content in liver0.70.82.6-1.60.8-0.70.7-0.70.7-0.60.6-0.80.30.31.11.11.11.1-0.71.21.00.60.7
Rb content in liver0.20.20.50.3-0.20.6-0.60.6-0.60.5-0.50.7-0.5-0.5-0.1-0.1-0.1-0.10.6-0.1-0.1-0.2-0.3
Se content in liver0.40.51.10.90.7-0.50.5-0.50.5-0.70.7-0.51.11.10.70.70.70.7-0.40.90.70.80.4
Sr content in liver0.10.10.4-0.2-0.60.2-0.20.2-0.20.3-0.40.30.00.0-0.2-0.2-0.1-0.1-0.0-0.1-0.2-0.7-0.2
Zn content in liver0.00.10.3-0.00.6-0.20.2-0.20.2-0.10.1-0.10.30.30.10.1-0.0-0.00.20.00.00.50.1
Bone: minimum diameter1.42.63.31.4-1.41.8-1.81.8-1.81.6-1.61.8-1.0-1.0-1.6-1.6-1.7-1.71.8-1.6-1.7-1.3-1.7
Time in familiar zone, hab. session 10.30.33.11.7-0.30.3-0.30.3-0.30.3-0.40.50.10.1-0.3-0.3-0.2-0.20.6-0.0-0.8-0.2-0.8
Time in novel zone, hab. session 10.30.34.2-2.00.1-0.20.2-0.20.20.1-0.0-0.2-0.7-0.70.20.20.20.2-0.20.00.5-0.10.3
Total zone transitions, hab. session 10.00.10.2-0.30.40.1-0.10.1-0.10.2-0.10.30.00.00.20.20.20.20.50.2-0.30.3-0.3
Total locomotion distance, hab. session 10.20.31.30.30.6-0.50.5-0.50.5-0.50.5-0.41.11.10.20.20.30.3-0.30.20.20.60.2
Locomotion velocity, hab. session 10.20.31.30.00.7-0.60.6-0.60.6-0.50.5-0.51.21.20.40.40.40.4-0.30.30.20.60.3
Time in familiar zone, hab. session 20.20.30.6-0.80.10.6-0.60.6-0.60.8-0.60.5-0.6-0.6-0.3-0.3-0.3-0.30.6-0.2-0.6-0.0-0.4
Time in novel zone, hab. session 20.10.10.70.8-0.5-0.10.1-0.10.1-0.0-0.10.1-0.1-0.1-0.4-0.4-0.5-0.50.2-0.6-0.2-0.4-0.4
Total zone transitions, hab. session 20.81.12.60.51.2-0.60.6-0.60.6-1.31.4-0.71.31.31.21.21.11.1-0.71.20.71.60.9
Total locomotion distance, hab. session 20.91.24.01.20.7-0.80.8-0.80.8-1.41.4-0.92.02.00.60.60.60.6-1.00.60.61.30.9
Locomotion velocity, hab. session 20.91.34.21.10.8-0.80.8-0.80.8-1.51.5-1.02.02.00.70.70.80.8-1.10.80.81.31.0
Novel to familiar place preference ratio0.50.51.2-0.4-0.70.7-0.70.7-0.70.8-0.80.7-1.1-1.1-0.5-0.5-0.6-0.60.7-0.7-0.2-0.9-0.6
Novelty place preference1.21.32.6-0.5-1.11.0-1.01.0-1.01.3-1.31.1-1.6-1.6-1.0-1.0-1.0-1.01.1-1.1-0.6-1.3-1.1
Time in novel zone, NPP test1.01.02.4-0.7-1.00.9-0.90.9-0.91.2-1.21.0-1.6-1.6-0.9-0.9-0.9-0.91.0-1.0-0.5-1.2-1.0
Total zone transitions, NPP test0.20.31.0-0.71.0-0.30.3-0.30.3-0.60.7-0.30.10.10.70.70.60.6-0.20.60.41.00.6
Total locomotion distance, NPP test1.11.52.4-0.11.4-0.90.9-0.90.9-1.41.4-1.11.61.61.21.21.11.1-1.21.11.11.51.4
Locomotion velocity, NPP test0.81.21.8-0.31.3-0.70.7-0.70.7-1.21.3-0.91.41.41.21.21.11.1-1.11.11.11.31.3
Intraocular pressure4.25.87.20.5-2.42.3-2.32.3-2.32.6-2.72.2-2.6-2.6-2.5-2.5-2.6-2.62.4-2.5-2.4-2.6-2.4
Delta distance traveled before/after self-admin0.10.10.40.3-0.4-0.20.2-0.20.2-0.20.1-0.20.10.10.30.30.20.2-0.60.10.1-0.40.3
Delta ambulatory time before/after self-admin0.20.20.8-0.00.0-0.50.5-0.50.5-0.40.4-0.50.50.50.50.50.50.5-0.90.30.3-0.10.6
Parametrial fat weight0.10.34.7-2.20.10.0-0.00.0-0.00.4-0.3-0.0-0.5-0.50.10.10.10.1-0.10.10.2-0.10.4
Pavlov. Cond. lever latency0.91.29.2-3.01.1-1.21.2-1.21.2-0.40.4-1.1-0.3-0.30.70.70.70.7-0.80.60.90.50.8
Pavlov. Cond. magazine entry latency0.20.22.51.6-0.2-0.20.2-0.20.2-0.60.5-0.10.80.80.10.10.20.2-0.40.30.00.20.2
Pavlov. Cond. change in total contacts1.01.010.63.3-1.01.1-1.11.1-1.10.1-0.21.10.50.5-0.5-0.5-0.5-0.50.8-0.4-0.6-0.3-0.7
Pavlov. Cond. index score0.60.710.03.2-0.90.7-0.70.7-0.7-0.20.10.60.70.7-0.3-0.3-0.2-0.20.1-0.1-0.5-0.2-0.3
Pavlov. Cond. latency score0.50.79.13.0-0.90.6-0.60.6-0.6-0.20.10.50.70.7-0.3-0.3-0.3-0.30.1-0.2-0.5-0.2-0.3
Pavlov. Cond. lever contacts1.21.411.23.4-1.31.3-1.31.3-1.30.4-0.51.20.20.2-0.8-0.8-0.7-0.70.8-0.6-1.0-0.7-0.9
Pavlov. Cond. magazine entry number0.91.18.4-2.90.20.4-0.40.4-0.41.2-1.00.5-1.5-1.5-0.8-0.8-0.8-0.81.0-1.0-0.5-0.3-0.7
Pavlov. Cond. intertrial magazine entries0.60.71.5-1.0-0.10.8-0.80.8-0.81.2-1.10.6-1.1-1.1-0.5-0.5-0.6-0.61.1-0.7-1.0-0.7-0.9
Pavlov. Cond. lever-magazine prob. diff.0.60.79.33.0-0.90.7-0.70.7-0.7-0.10.00.60.50.5-0.3-0.3-0.2-0.20.2-0.1-0.5-0.3-0.4
Pavlov. Cond. response bias0.70.812.33.5-0.80.3-0.30.3-0.3-0.50.40.30.90.90.10.10.10.1-0.30.3-0.1-0.3-0.0
Pavlov. Cond. lever latency0.10.21.81.3-0.20.0-0.00.0-0.0-0.20.30.00.50.5-0.4-0.4-0.3-0.30.0-0.4-0.00.40.0
Pavlov. Cond. magazine entry latency2.73.17.5-2.71.7-1.81.8-1.81.8-1.51.5-1.81.61.61.71.71.71.7-1.91.81.71.21.8
Pavlov. Cond. change in total contacts0.10.21.7-1.3-0.1-0.40.4-0.40.40.2-0.3-0.1-0.1-0.10.20.20.20.2-0.20.30.0-0.6-0.0
Pavlov. Cond. index score1.31.66.6-2.61.3-1.31.3-1.31.3-0.90.9-1.30.80.81.31.31.31.3-1.21.41.10.61.1
Pavlov. Cond. latency score1.72.26.7-2.61.4-1.61.6-1.61.6-1.21.1-1.51.11.11.41.41.41.4-1.51.51.30.81.4
Pavlov. Cond. lever contacts0.10.21.2-1.10.4-0.20.2-0.20.2-0.10.1-0.2-0.2-0.20.50.50.60.6-0.30.70.30.00.3
Pavlov. Cond. magazine entry number0.91.13.92.0-0.91.1-1.11.1-1.10.8-0.81.1-0.9-0.9-0.9-0.9-0.9-0.91.2-1.1-1.0-0.5-1.1
Pavlov. Cond. intertrial magazine entries1.82.43.11.7-1.41.5-1.51.5-1.51.4-1.41.4-1.8-1.8-1.6-1.6-1.6-1.61.6-1.7-1.5-1.1-1.6
Pavlov. Cond. lever-magazine prob. diff.1.41.86.7-2.61.3-1.51.5-1.51.5-1.01.0-1.40.90.91.31.31.31.3-1.41.41.20.61.2
Pavlov. Cond. response bias0.30.43.0-1.70.6-0.40.4-0.40.4-0.20.2-0.40.00.00.70.70.70.7-0.40.80.50.10.4
Time in closed arm before self-admin0.10.10.20.30.3-0.50.5-0.50.5-0.40.4-0.40.30.30.10.10.20.2-0.40.10.10.30.3
Time in closed arm after self-admin0.50.50.8-0.00.7-0.80.8-0.80.8-0.60.6-0.80.90.90.70.70.70.7-0.90.60.70.40.6
Time in open arm before self-admin1.71.82.7-1.41.6-1.21.2-1.21.2-1.31.4-1.31.51.51.31.31.21.2-1.21.41.51.61.3
Time in open arm after self-admin0.10.10.40.0-0.20.2-0.20.2-0.20.3-0.30.2-0.0-0.0-0.6-0.6-0.5-0.50.2-0.4-0.4-0.1-0.3
Bone: periosteal estimation2.45.06.71.8-2.12.6-2.62.6-2.62.2-2.22.5-2.1-2.1-2.0-2.0-2.1-2.12.5-2.0-2.1-1.9-2.3
Bone: periosteal perimeter2.64.35.92.0-2.12.4-2.42.4-2.42.1-2.12.4-1.5-1.5-2.0-2.0-2.0-2.02.3-1.8-2.0-1.9-2.1
Bone: post-yield work0.20.30.90.3-0.01.0-1.01.0-1.00.4-0.30.6-0.5-0.5-0.1-0.1-0.2-0.21.0-0.1-0.60.3-0.6
Progressive ratio test 1 active lever presses0.30.41.01.0-0.70.6-0.60.6-0.60.5-0.50.6-0.5-0.5-0.4-0.4-0.4-0.40.6-0.6-0.6-0.7-0.7
Progressive ratio test 1 breakpoint0.70.71.11.1-0.90.9-0.90.9-0.90.8-0.90.9-0.8-0.8-0.7-0.7-0.7-0.70.9-0.9-0.9-1.0-1.0
Progressive ratio test 1 inactive lever presses0.30.30.40.1-0.40.5-0.50.5-0.50.6-0.50.5-0.5-0.5-0.7-0.7-0.6-0.60.6-0.7-0.6-0.4-0.7
Progressive ratio test 2 active lever presses0.10.10.30.4-0.30.5-0.50.5-0.50.3-0.40.5-0.5-0.5-0.1-0.1-0.1-0.10.4-0.3-0.3-0.3-0.3
Progressive ratio test 2 breakpoint0.20.20.40.6-0.40.5-0.50.5-0.50.4-0.40.5-0.5-0.5-0.1-0.1-0.1-0.10.4-0.3-0.4-0.4-0.3
Progressive ratio test 2 inactive lever presses0.10.10.30.4-0.20.2-0.20.2-0.20.3-0.30.2-0.3-0.30.00.00.10.10.1-0.0-0.1-0.6-0.1
Incentive Sensitization - Responses0.00.00.1-0.00.10.2-0.20.2-0.20.3-0.20.2-0.3-0.30.10.10.10.10.3-0.0-0.10.0-0.0
Incentive Sensitization - Breakpoint0.00.00.1-0.20.30.2-0.20.2-0.20.3-0.20.2-0.3-0.30.10.10.10.10.4-0.0-0.10.1-0.0
Sum of active levers in priming session hrs 5-60.60.61.4-1.01.2-0.70.7-0.70.7-0.70.8-0.70.80.80.60.60.60.6-0.50.80.91.20.9
Progressive ratio1.72.03.41.8-1.71.4-1.41.4-1.41.2-1.31.3-1.2-1.2-1.3-1.3-1.3-1.31.2-1.5-1.5-1.6-1.5
Food seeking constrained by brief footshock2.93.65.71.1-2.31.9-1.91.9-1.92.0-2.11.8-2.0-2.0-1.9-1.9-1.9-1.91.6-1.7-1.8-2.4-1.7
Seeking ratio, punishment vs. effort0.50.62.4-1.50.8-0.70.7-0.70.7-0.50.6-0.70.40.40.60.60.60.6-0.60.90.80.70.9
Retroperitoneal fat weight0.10.56.0-2.40.30.2-0.20.2-0.20.8-0.60.2-0.9-0.90.10.10.10.10.50.1-0.0-0.10.0
Reaction time number correct0.30.40.9-1.0-0.70.4-0.40.4-0.40.6-0.50.4-0.6-0.6-1.0-1.0-0.9-0.90.2-0.9-0.8-0.5-0.5
Reaction time mean minus median0.50.61.00.50.6-0.80.8-0.80.8-0.90.8-0.80.80.80.90.90.90.9-0.80.91.00.50.5
Reaction time mean minus median AUC0.60.71.10.20.8-0.90.9-0.90.9-0.90.9-0.91.11.10.80.80.90.9-0.80.91.00.70.5
Reaction time num false alarms0.40.61.2-0.00.6-1.11.1-1.11.1-1.00.9-0.90.60.60.60.60.60.6-0.70.50.40.60.6
Reaction time num false alarms AUC0.50.71.50.40.5-1.21.2-1.21.2-1.11.0-1.00.80.80.60.60.60.6-0.90.60.50.60.7
Reaction time trials correct on left0.30.40.9-1.0-0.70.4-0.40.4-0.40.6-0.50.4-0.6-0.6-1.0-1.0-0.9-0.90.2-0.9-0.8-0.5-0.5
Reaction time trials on left0.30.40.8-0.9-0.60.4-0.40.4-0.40.5-0.40.3-0.5-0.5-0.9-0.9-0.8-0.80.2-0.8-0.7-0.4-0.5
Reaction time mean0.40.50.60.80.8-0.80.8-0.80.8-0.80.7-0.70.70.70.80.80.80.8-0.50.70.80.60.6
Reaction time mean AUC0.30.41.01.00.6-0.60.6-0.60.6-0.70.7-0.60.60.60.70.70.70.7-0.50.70.80.50.4
Median of all reaction times0.30.40.70.90.6-0.60.6-0.60.6-0.60.5-0.50.60.60.60.60.60.6-0.30.60.60.50.5
Reaction time omissions0.20.33.21.80.40.0-0.00.0-0.0-0.50.5-0.10.80.80.40.40.50.50.10.40.30.70.1
Reaction time false alarm rate1.21.62.30.51.1-1.51.5-1.51.5-1.51.4-1.31.31.31.31.31.21.2-1.11.21.01.11.1
Reaction time premature initiation rate0.30.43.9-2.00.50.4-0.40.4-0.40.6-0.40.4-0.7-0.70.00.0-0.0-0.00.7-0.2-0.20.3-0.4
Reaction time premature initiations0.60.86.4-2.50.00.7-0.70.7-0.70.9-0.70.6-1.1-1.1-0.5-0.5-0.6-0.60.8-0.7-0.70.0-0.7
Std. dev. reaction times0.81.11.71.10.9-1.01.0-1.01.0-1.31.2-1.11.21.21.01.01.01.0-1.01.01.10.90.7
Reaction time trials completed0.30.40.8-0.9-0.60.4-0.40.4-0.40.5-0.40.3-0.5-0.5-0.9-0.9-0.8-0.80.2-0.8-0.7-0.4-0.5
Reaction time trials AUC0.20.30.8-0.9-0.50.3-0.30.3-0.30.4-0.40.2-0.5-0.5-0.7-0.7-0.6-0.60.1-0.6-0.6-0.3-0.4
Run reversals in cocaine runway, females1.31.32.2-1.1-1.01.0-1.01.0-1.01.5-1.40.9-1.1-1.1-1.1-1.1-1.2-1.21.1-1.2-1.0-1.2-1.3
Run reversals in cocaine runway, males0.10.10.30.6-0.50.2-0.20.2-0.20.1-0.10.2-0.2-0.2-0.4-0.4-0.4-0.40.1-0.3-0.2-0.3-0.0
Latency to leave start box in cocaine runway1.01.12.3-1.21.4-0.90.9-0.90.9-1.11.1-1.01.01.01.01.01.11.1-0.71.00.81.51.0
Latency to leave start box in cocaine runway, F0.50.61.5-1.21.0-0.60.6-0.60.6-0.70.7-0.70.70.70.80.80.80.8-0.60.70.60.90.7
Latency to leave start box in cocaine runway, M0.40.40.7-0.20.8-0.60.6-0.60.6-0.60.7-0.60.60.60.70.70.60.6-0.50.70.50.90.7
Std. dev. time between licks in bursts1.11.34.92.2-1.30.9-0.90.9-0.90.7-0.70.9-0.2-0.2-1.5-1.5-1.4-1.41.1-1.4-1.3-0.8-1.2
Total sessions with >9 infusions0.30.40.6-0.40.6-0.60.6-0.60.6-0.40.4-0.60.60.60.60.60.80.8-0.70.70.60.20.6
Short access day 1 total inactive lever presses0.10.10.50.7-0.1-0.10.1-0.10.10.2-0.2-0.10.10.10.20.20.30.3-0.30.10.2-0.60.1
Short access day 10 total inactive lever presses0.10.20.3-0.10.4-0.30.3-0.30.3-0.50.5-0.30.30.30.50.50.40.4-0.50.50.40.50.4
Short access day 1 total infusions0.50.50.90.20.8-0.80.8-0.80.8-0.50.5-0.80.80.80.80.80.90.9-0.70.80.80.30.8
Short access day 10 total infusions0.50.50.90.6-0.60.8-0.80.8-0.80.8-0.80.8-0.8-0.8-0.4-0.4-0.3-0.30.9-0.6-0.7-0.8-0.8
Short access total infusions0.00.00.20.40.00.1-0.10.1-0.10.2-0.20.1-0.1-0.10.20.20.20.20.10.10.1-0.4-0.0
Short access day 1 locomotion0.10.11.41.2-0.2-0.00.0-0.00.00.2-0.3-0.00.10.10.20.20.10.1-0.1-0.0-0.1-0.6-0.1
Short access day 10 total locomotion0.20.21.01.00.4-0.30.3-0.30.3-0.40.3-0.30.70.70.40.40.60.6-0.40.40.30.10.4
Short access total locomotion0.30.30.60.50.6-0.50.5-0.50.5-0.50.4-0.50.70.70.70.70.80.8-0.60.60.50.10.6
One hour access (0.3 mA shock)0.50.61.41.2-0.80.9-0.90.9-0.90.7-0.70.9-0.7-0.7-0.5-0.5-0.5-0.50.7-0.6-0.6-0.8-0.5
Compulsive drug intake0.80.81.3-0.40.9-0.90.9-0.90.9-0.90.9-0.91.11.10.80.80.70.7-1.00.90.91.01.1
One hour access (shock baseline)2.02.33.11.0-1.61.6-1.61.6-1.61.6-1.71.6-1.7-1.7-1.4-1.4-1.2-1.21.6-1.4-1.5-1.8-1.6
Social response proportion0.40.42.31.5-0.1-0.50.5-0.50.5-0.70.6-0.40.90.90.40.40.40.4-0.90.30.7-0.10.6
Social responses0.20.21.81.3-0.90.1-0.10.1-0.1-0.1-0.10.2-0.3-0.3-0.5-0.5-0.5-0.5-0.1-0.6-0.3-0.9-0.2
Social time1.31.72.60.70.9-1.21.2-1.21.2-1.51.3-1.21.31.31.61.61.51.5-1.41.51.40.81.2
Soleus weight0.20.51.30.31.00.1-0.10.1-0.1-0.60.6-0.50.40.41.11.11.01.0-0.20.90.71.00.6
Bone: stiffness2.33.64.81.6-1.72.1-2.12.1-2.11.7-1.62.0-1.4-1.4-2.1-2.1-2.1-2.12.1-2.0-2.2-1.2-1.9
Tibialis anterior weight0.20.65.12.3-1.10.7-0.70.7-0.70.2-0.30.6-0.0-0.0-0.8-0.8-0.9-0.90.4-0.7-0.6-0.6-0.4
Time to tail flick, vehicle, before self-admin1.61.72.2-1.01.5-1.31.3-1.31.3-1.31.3-1.31.11.11.31.31.31.3-1.11.41.41.41.4
Time to tail flick, vehicle, after self-admin0.10.10.2-0.40.1-0.20.2-0.20.20.0-0.1-0.30.10.10.30.30.30.3-0.40.30.3-0.30.3
Time to tail flick, test, before self-admin2.42.34.5-0.2-1.91.4-1.41.4-1.41.9-1.91.4-1.2-1.2-1.7-1.7-1.7-1.71.1-1.5-1.4-2.1-1.1
Time to tail flick, test, after self-admin1.31.31.9-1.01.2-0.90.9-0.90.9-1.01.0-1.01.31.31.31.31.41.4-0.91.21.31.31.1
Delta time to tail flick, vehicle, before/after SA0.20.20.80.8-0.80.3-0.30.3-0.30.4-0.50.3-0.3-0.3-0.3-0.3-0.3-0.30.1-0.6-0.5-0.9-0.5
Delta time to tail flick, test, before/after SA3.63.35.8-0.62.2-1.61.6-1.61.6-2.12.1-1.71.61.62.02.02.02.0-1.41.81.82.41.5
Tibia length8.824.730.54.3-4.75.5-5.55.5-5.54.9-4.85.5-4.4-4.4-5.0-5.0-5.0-5.05.4-5.0-5.1-4.0-4.9
Ambulatory time before self-admin4.14.35.61.0-2.02.2-2.22.2-2.22.1-2.12.2-2.4-2.4-1.9-1.9-2.0-2.02.3-1.9-1.9-2.0-2.1
Ambulatory time after self-admin2.83.05.00.7-2.21.7-1.71.7-1.71.9-1.91.7-1.8-1.8-1.7-1.7-1.7-1.71.5-1.7-1.7-2.1-1.6
Bone: tissue strength0.50.51.31.2-0.70.8-0.80.8-0.80.7-0.70.8-0.2-0.2-0.6-0.6-0.6-0.60.8-0.5-0.7-0.5-0.6
Total heroin consumption0.10.20.3-0.4-0.30.4-0.40.4-0.40.4-0.40.4-0.4-0.4-0.6-0.6-0.5-0.50.4-0.2-0.2-0.2-0.4
Bone: trabecular number0.00.00.2-0.50.0-0.10.1-0.10.1-0.20.2-0.2-0.2-0.2-0.0-0.0-0.0-0.0-0.20.00.10.10.0
Bone: trabecular spacing0.10.10.4-0.30.4-0.00.0-0.00.0-0.0-0.0-0.20.30.30.60.60.50.5-0.20.50.40.00.3
Bone: trabecular thickness1.11.31.90.3-1.11.0-1.01.0-1.01.1-1.01.2-1.3-1.3-1.4-1.4-1.3-1.31.1-1.3-1.3-0.8-1.2
Bone: trabecular tissue density0.40.63.21.80.5-0.50.5-0.50.5-0.80.8-0.31.41.4-0.1-0.1-0.0-0.0-0.10.0-0.21.10.1
Water consumed over 24 hours0.60.71.40.5-1.00.7-0.70.7-0.70.7-0.70.6-0.3-0.3-1.2-1.2-1.1-1.10.5-1.0-0.9-0.9-0.8
Number of responses in last shaping day1.91.92.80.31.4-1.51.5-1.51.5-1.51.4-1.51.71.71.51.51.31.3-1.31.51.31.01.3