Hub : Genes

Erc2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Erc2 0.58 0.06 1.3e-12 0.2 0.19 0.25 0.22 7.2e-11 1.6e-10 1.1e-13 4.9e-12
2 PL intron excision ratio chr16_3234360_3244650 0.12 0.07 3.9e-05 0.04 0.03 0.04 0.03 2.4e-05 4.9e-04 3.5e-05 2.5e-04
3 Brain intron excision ratio chr16_3230106_3244650 0.06 0.04 1.9e-03 0.03 0.02 0.01 0.02 1.3e-03 3.4e-03 8.4e-02 8.3e-03
4 BLA intron excision ratio chr16_3234360_3244650 0.17 0.08 3.5e-04 0.08 0.07 0.08 0.1 5.8e-05 1.2e-04 4.2e-05 9.3e-06
5 BLA intron excision ratio chr16_3230106_3244650 0.13 0.08 5.5e-03 0.07 0.04 0.07 0.08 1.5e-04 2.3e-03 1.2e-04 7.0e-05
6 PL intron excision ratio chr16_3230106_3244650 0.23 0.11 3.0e-08 0.08 0.06 0.08 0.08 5.0e-09 1.3e-07 2.4e-09 5.3e-09
7 NAcc gene expression Erc2 0.31 0.11 2.7e-14 0.13 0.1 0.15 0.13 1.9e-14 1.1e-11 4.6e-17 1.9e-14
8 PL intron excision ratio chr16_3230106_3234325 0.19 0.1 2.2e-06 0.08 0.06 0.07 0.07 8.1e-09 5.1e-07 4.1e-08 1.4e-08
9 NAcc mRNA stability Erc2 0.19 0.08 1.0e-10 0.11 0.07 0.1 0.1 1.8e-12 6.1e-09 1.2e-11 3.4e-12
10 Liver gene expression Erc2 0.45 0.13 1.8e-12 0.04 0.06 0.08 0.05 3.8e-05 2.4e-07 2.1e-09 6.8e-06
11 Brain gene expression Erc2 0.78 0.08 0.0e+00 0.36 0.36 0.4 0.38 1.8e-35 2.8e-35 9.6e-40 6.0e-37
12 Brain isoform ratio NM_001401498.1 0.1 0.06 4.3e-04 0.05 0.01 0.04 0.04 1.2e-05 1.8e-02 3.1e-04 4.8e-05
13 LHb gene expression Erc2 0.31 0.15 3.9e-03 0.1 0.11 0.05 0.12 1.8e-03 1.2e-03 2.1e-02 9.6e-04
14 pVTA gene expression Erc2 0.34 0.14 7.0e-05 0.07 0.06 0.06 0.08 8.4e-04 9.3e-04 9.5e-04 2.6e-04
15 Brain mRNA stability Erc2 0.39 0.12 0.0e+00 0.19 0.18 0.21 0.2 3.9e-17 2.5e-16 6.0e-19 2.9e-18
16 OFC gene expression Erc2 0.81 0.1 6.7e-13 0.42 0.46 0.5 0.52 2.6e-11 3.1e-12 1.2e-13 2.4e-14
17 PL gene expression Erc2 0.54 0.07 0.0e+00 0.18 0.24 0.27 0.26 1.3e-19 3.2e-26 4.4e-30 4.9e-29
18 Brain alternative TSS NM_170787.3 0.04 0.03 2.8e-03 0.01 0.03 0.03 0.02 2.0e-02 6.4e-04 1.9e-03 6.8e-03
19 Brain alternative TSS NM_170787.3 0.04 0.03 3.1e-03 0.01 0.03 0.03 0.02 2.3e-02 7.7e-04 2.0e-03 9.0e-03
20 Brain isoform ratio XR_005494539.1 0.06 0.04 1.9e-04 0.02 0.04 0.04 0.04 8.6e-03 7.0e-05 4.9e-05 1.0e-04
21 LHb mRNA stability Erc2 0.41 0.23 4.4e-04 0.08 0.18 0.16 0.15 6.8e-03 5.9e-05 1.5e-04 1.8e-04
22 IL gene expression Erc2 0.26 0.14 1.3e-03 0.04 0.08 0.09 0.06 3.3e-02 5.2e-03 4.6e-03 1.4e-02
23 PL intron excision ratio chr16_2812967_2848537 0.04 0.02 1.1e-04 0.04 0.02 0.03 0.03 1.6e-05 2.3e-03 1.1e-04 2.9e-04
24 PL intron excision ratio chr16_2819055_2848537 0.02 0.01 2.1e-03 0.04 0.03 0.03 0.04 4.2e-05 8.4e-04 2.3e-04 9.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.42.45.61.82.3-2.4-2.12.1-2.01.02.20.7-2.00.41.2-0.8-1.60.4-0.30.91.51.42.30.50.8-1.31.3
Area under the delay curve0.10.21.7-0.20.10.10.3-0.30.3-0.5-0.3-0.01.30.3-0.40.3-0.4-0.10.40.20.40.4-0.30.10.10.2-0.2
BMI with tail1.13.46.52.52.3-2.5-2.42.4-2.42.52.42.6-1.12.42.1-1.8-1.11.4-1.20.81.41.50.6-0.20.31.6-1.6
BMI without tail2.24.510.13.22.2-2.4-2.82.8-2.83.22.82.4-1.02.82.6-2.1-1.82.0-1.71.90.80.91.0-0.81.30.9-0.9
Body weight1.45.911.62.72.7-2.8-2.82.7-2.83.32.63.4-2.43.13.0-3.1-2.12.7-2.81.8-0.1-0.01.4-1.91.50.7-0.7
Weight adjusted by age0.70.72.7-0.9-1.51.70.9-0.90.9-1.1-0.8-1.31.2-0.3-0.60.90.5-0.10.40.2-0.9-0.9-1.1-0.20.1-0.10.1
Bone surface0.91.64.11.52.0-2.0-1.71.7-1.71.21.81.1-1.30.51.0-0.8-1.20.4-0.30.71.41.31.60.40.5-0.40.5
Bone volume1.01.74.51.42.1-2.0-1.81.8-1.71.41.81.7-1.60.81.2-1.2-1.20.8-0.60.51.31.31.40.10.40.1-0.0
Breakpoint value in progressive ratio session1.01.14.7-1.6-1.11.21.3-1.31.2-1.0-1.3-0.82.2-0.5-1.21.10.8-0.91.0-0.60.00.0-1.30.5-0.60.4-0.4
Number of licking bursts0.10.10.40.4-0.30.2-0.40.4-0.40.40.4-0.00.60.60.40.00.10.20.00.20.30.4-0.50.1-0.00.5-0.5
Context. condit. distance diff. score0.10.10.4-0.2-0.30.10.2-0.20.1-0.3-0.2-0.60.3-0.3-0.40.60.4-0.50.6-0.20.40.30.00.5-0.1-0.20.2
Locomotion velocity, session 15.35.712.6-2.9-3.53.13.1-3.13.1-2.4-3.0-2.93.2-1.9-2.62.52.7-1.81.8-1.7-1.3-1.3-2.40.6-1.50.6-0.6
Locomotion distance, session 13.03.88.8-2.6-3.02.92.6-2.72.7-2.0-2.7-1.71.7-1.2-1.91.42.2-1.00.7-1.5-1.8-1.8-2.4-0.3-1.00.8-0.7
Locomotion velocity, session 22.52.96.1-2.2-2.32.32.2-2.32.3-2.2-2.4-1.80.1-1.7-1.61.11.3-0.80.3-0.8-2.5-2.5-1.0-0.70.1-0.80.8
Locomotion distance, session 21.52.14.5-1.7-2.12.12.0-2.02.0-1.0-2.1-0.51.5-0.5-1.10.61.5-0.30.1-0.9-1.7-1.6-2.0-0.7-0.71.2-1.2
Locomotion velocity, session 33.54.17.5-2.4-2.52.62.7-2.72.7-1.8-2.7-1.02.3-1.4-2.21.62.3-1.31.3-1.9-0.9-0.8-2.70.3-1.81.7-1.7
Locomotion distance, session 32.22.47.7-1.1-1.01.01.1-1.11.1-0.2-0.90.32.3-0.3-1.11.11.9-1.01.3-1.91.31.4-2.31.3-2.22.8-2.8
Stereotopy head waving bouts, day 30.00.10.30.20.10.00.1-0.10.2-0.1-0.1-0.10.5-0.3-0.30.3-0.1-0.30.3-0.10.30.3-0.10.3-0.30.1-0.1
Stereotopy head waving duration, day 30.30.31.30.40.6-0.4-0.20.2-0.2-0.30.2-0.5-0.4-0.7-0.30.4-0.5-0.60.50.20.50.40.90.60.1-1.11.1
Locomotion velocity, session 73.53.815.7-2.0-2.62.52.2-2.22.2-0.5-2.4-0.44.0-0.1-1.61.12.1-0.40.8-1.1-0.8-0.7-3.2-0.2-1.52.7-2.6
Locomotion distance, session 71.01.33.4-1.4-1.51.31.1-1.11.1-0.5-1.2-0.31.8-0.1-0.90.81.6-0.50.7-1.10.00.1-1.80.3-1.21.7-1.7
Stereotopy head waving bouts, day 71.82.04.42.11.5-1.4-1.61.6-1.61.81.61.2-0.41.51.5-1.4-1.91.5-1.21.9-0.0-0.11.4-1.01.5-0.70.7
Stereotopy head waving duration, day 71.92.35.42.31.6-1.6-1.81.8-1.81.81.81.1-0.71.51.7-1.4-2.11.5-1.32.10.0-0.01.6-0.91.7-0.90.9
Locomotion velocity, session 88.39.918.4-3.9-4.14.04.3-4.34.3-3.4-4.2-3.43.9-3.0-3.73.33.0-2.62.5-2.2-1.5-1.5-3.00.9-2.00.5-0.5
Locomotion distance, session 82.43.56.9-2.4-2.62.62.6-2.62.6-1.6-2.6-1.42.1-1.1-1.91.42.0-0.90.9-1.3-1.5-1.4-2.4-0.1-1.01.1-1.1
Degree of sensitization distance0.40.41.4-0.3-0.20.10.1-0.10.1-0.2-0.2-0.4-0.6-0.00.2-0.4-0.30.5-0.70.6-1.2-1.20.5-0.90.9-1.01.0
Degree of sensitization stereotypy1.92.14.71.91.4-1.3-1.51.5-1.51.71.40.9-0.61.51.6-1.4-2.01.6-1.42.2-0.5-0.51.5-1.31.9-1.11.1
Conditioned locomotion0.91.03.01.71.0-0.9-1.41.4-1.41.51.51.0-0.31.31.2-0.8-1.00.8-0.61.10.60.60.5-0.20.70.2-0.2
Cocaine response after cond. corrected0.10.10.5-0.2-0.40.30.5-0.50.5-0.5-0.4-0.70.1-0.6-0.40.40.1-0.40.3-0.1-0.2-0.20.20.2-0.0-0.50.5
Cocaine response after cond. not corrected0.20.21.0-0.1-0.40.20.3-0.20.2-0.6-0.2-0.8-0.9-0.5-0.10.10.0-0.2-0.00.0-0.5-0.60.5-0.10.4-1.01.0
Cocaine response before conditioning0.20.21.4-0.7-0.30.40.2-0.20.2-0.7-0.3-0.4-1.2-0.5-0.20.20.6-0.30.1-0.7-0.2-0.2-0.10.1-0.2-0.20.2
Saline control response0.81.03.50.80.2-0.4-0.90.9-0.81.50.91.41.31.50.9-0.80.10.9-0.50.10.80.9-0.9-0.1-0.51.9-1.9
Bone: connectivity density2.54.011.02.42.4-2.7-2.62.6-2.60.92.70.1-2.40.51.5-0.8-2.30.6-0.51.81.21.13.30.31.9-2.62.6
Bone: cortical apparent density2.43.17.0-1.8-1.21.31.6-1.61.6-2.3-1.6-1.90.2-2.7-2.22.31.9-2.62.3-2.21.01.0-1.02.1-1.90.1-0.1
Bone: cortical area4.87.215.53.33.8-3.7-3.63.5-3.53.83.43.9-1.02.92.6-2.3-1.81.7-1.21.02.82.91.30.20.11.9-1.9
Bone: cortical porosity1.31.54.70.3-0.40.40.2-0.20.21.2-0.21.31.42.01.0-1.4-0.71.9-1.71.2-1.8-1.7-0.8-2.20.90.9-0.9
Bone: cortical porosity1.11.23.40.2-0.40.40.2-0.20.21.1-0.21.31.41.80.9-1.2-0.41.7-1.50.8-1.4-1.4-0.9-1.80.61.2-1.2
Bone: cortical thickness2.33.78.82.42.8-2.7-2.42.4-2.33.02.32.90.12.11.8-1.8-1.61.4-1.01.11.81.91.0-0.10.31.3-1.3
Bone: cortical thickness2.73.27.02.52.6-2.6-2.32.3-2.32.32.51.9-1.01.61.9-1.4-1.91.1-0.91.41.51.51.7-0.00.9-0.10.1
Bone: cortical tissue density3.04.08.7-2.1-1.51.61.9-1.91.9-2.6-1.8-2.30.3-3.0-2.52.52.1-2.92.5-2.41.00.9-1.12.3-2.00.1-0.0
Condit. Reinf. active minus inactive responses0.70.83.1-0.50.4-0.30.0-0.00.0-0.30.00.10.2-0.7-0.70.90.8-1.11.3-1.31.81.8-0.21.6-1.30.7-0.7
Condit. Reinf. active-inactive response ratio2.12.311.90.71.8-1.8-1.41.4-1.40.31.40.2-0.6-0.5-0.20.80.1-1.31.7-0.93.43.41.12.7-1.1-0.0-0.0
Condit. Reinf. active responses0.20.30.7-0.5-0.20.30.3-0.30.4-0.5-0.3-0.20.2-0.5-0.60.60.7-0.70.7-0.80.50.5-0.50.7-0.70.5-0.6
Condit. Reinf. inactive responses1.21.45.2-0.9-1.92.01.4-1.41.4-0.8-1.5-0.50.80.1-0.30.00.70.4-0.70.0-2.3-2.2-1.6-1.40.20.6-0.6
Incentive salience index mean0.30.31.6-0.00.3-0.4-0.20.2-0.20.20.30.20.7-0.0-0.30.40.3-0.50.8-0.51.31.3-0.10.9-0.70.6-0.6
Condit. Reinf. lever presses0.10.11.00.30.1-0.4-0.30.3-0.30.60.30.21.00.60.2-0.1-0.20.30.00.40.30.30.1-0.00.10.3-0.3
Condit. Reinf. active minus inactive responses0.40.56.10.4-0.20.20.1-0.10.11.0-0.00.42.50.80.1-0.0-0.10.40.10.60.20.3-0.7-0.2-0.21.1-1.1
Condit. Reinf. active-inactive response ratio1.71.86.11.71.2-1.3-1.21.2-1.22.51.31.61.41.81.4-1.4-1.51.7-1.21.80.10.10.5-1.10.90.7-0.7
Condit. Reinf. active responses0.20.33.1-0.1-0.50.60.3-0.30.30.1-0.3-0.11.80.3-0.30.40.3-0.10.4-0.10.40.4-0.90.2-0.50.9-0.9
Condit. Reinf. inactive responses1.41.84.1-1.7-1.92.01.5-1.51.5-2.0-1.6-1.50.5-1.2-1.41.41.5-1.21.1-1.3-0.5-0.5-1.40.6-0.90.1-0.1
Condit. Reinf. lever presses0.30.41.40.1-0.1-0.1-0.50.5-0.50.20.50.3-0.00.30.10.20.6-0.30.4-0.81.11.2-0.60.8-1.01.0-1.0
Condit. Reinf. lever reinforcers received0.30.43.6-0.0-0.40.40.2-0.20.20.2-0.20.11.90.3-0.30.40.3-0.10.5-0.20.60.7-0.90.4-0.71.1-1.1
Conditioned reinforcement - actives1.11.12.40.20.7-0.6-0.50.5-0.51.30.60.8-0.70.61.2-1.3-1.21.4-1.61.4-1.3-1.30.9-1.51.1-1.01.0
Conditioned reinforcement - inactives1.41.63.51.11.9-1.8-1.71.7-1.81.21.71.5-1.81.31.2-1.0-0.70.6-0.50.01.41.40.80.4-0.10.5-0.5
Conditioned locomotion0.30.31.1-0.50.20.1-0.30.2-0.30.60.10.9-0.50.50.7-0.8-0.00.8-1.00.1-0.8-0.8-0.4-1.00.00.5-0.5
Patch foraging indifference point 0 sec1.22.04.9-1.2-1.30.70.7-0.70.7-0.7-0.8-1.21.2-1.1-1.31.42.2-1.81.7-2.11.51.5-1.22.0-2.11.2-1.2
Patch foraging indifference point AUC0.50.62.11.30.3-0.2-0.90.9-0.90.90.80.10.20.90.9-0.5-0.90.8-0.61.4-0.3-0.30.4-0.61.0-0.50.5
Delay disc. indifference point, 0s delay0.91.02.61.50.6-0.6-0.90.9-0.91.50.80.91.21.60.9-0.9-1.11.3-0.91.6-0.3-0.20.1-1.01.10.4-0.4
Delay disc. indifference point, 16s delay0.91.05.1-1.5-1.01.01.3-1.31.3-0.9-1.2-0.72.3-0.5-0.90.70.4-0.60.6-0.3-0.2-0.2-1.20.0-0.50.9-0.9
Delay disc. indifference point, 2s delay0.40.51.50.6-0.10.10.3-0.30.3-0.9-0.3-0.60.5-0.3-0.81.00.1-1.01.2-0.51.11.1-0.21.2-0.60.3-0.3
Delay disc. indifference point, 24s delay1.41.44.1-0.9-1.41.61.6-1.61.5-2.0-1.5-1.50.5-1.1-1.51.40.8-1.21.1-0.8-0.4-0.4-0.90.5-0.3-0.50.5
Delay disc. indifference point, 4s delay0.40.42.10.70.9-0.6-0.60.6-0.6-0.10.60.40.40.5-0.10.2-0.8-0.10.70.31.51.40.30.80.1-0.10.1
Delay disc. indifference point, 8s delay0.20.21.00.00.2-0.1-0.10.1-0.2-0.20.20.1-0.10.30.2-0.3-0.80.6-0.40.7-0.4-0.40.5-0.60.9-1.01.0
Indifference point function ln k0.40.62.0-0.90.2-0.30.4-0.40.4-0.0-0.30.60.3-0.5-0.50.10.9-0.60.5-1.40.91.0-0.50.8-1.41.3-1.3
Indifference point function log k0.40.62.0-0.90.2-0.30.4-0.40.4-0.0-0.30.60.3-0.5-0.50.10.9-0.60.5-1.40.91.0-0.50.8-1.41.3-1.3
Patch foraging total patch changes 0 sec1.21.94.8-1.2-1.20.60.6-0.60.6-0.7-0.7-1.11.2-1.1-1.31.42.2-1.81.7-2.11.61.6-1.22.1-2.11.3-1.3
Patch foraging total patch changes 12 sec0.40.51.3-1.0-0.91.00.7-0.70.7-0.6-0.8-0.7-0.1-0.8-0.70.61.1-0.80.4-0.9-0.3-0.3-0.70.4-0.80.0-0.0
Patch foraging total patch changes 18 sec0.60.81.8-0.2-1.00.60.2-0.20.2-0.4-0.2-1.01.2-0.3-0.61.11.2-1.01.2-0.91.11.2-0.91.3-1.00.9-0.9
Patch foraging total patch changes 24 sec0.20.30.70.60.0-0.4-0.70.7-0.70.40.6-0.50.20.00.10.3-0.0-0.30.40.20.90.80.60.8-0.0-0.40.4
Patch foraging total patch changes 6 sec0.30.41.70.1-0.40.2-0.20.2-0.3-0.00.2-0.80.9-0.2-0.40.90.7-0.91.1-0.41.21.2-0.31.3-0.70.3-0.3
Patch foraging time to switch 0 sec0.71.03.4-0.6-0.70.70.9-0.91.0-1.4-1.0-1.3-0.8-1.3-0.70.5-0.2-0.30.10.2-1.4-1.40.7-0.50.9-1.81.8
Patch foraging water rate 0 sec0.91.45.80.81.4-1.3-1.41.5-1.51.31.51.1-0.00.70.6-0.2-0.0-0.20.4-0.42.42.40.11.4-1.01.1-1.1
Patch foraging water rate 12 sec0.61.04.1-0.30.4-0.1-0.10.1-0.1-0.20.10.00.7-0.3-0.70.90.8-1.11.4-1.22.02.0-0.61.7-1.41.1-1.1
Patch foraging water rate 18 sec0.50.73.30.51.3-1.0-1.01.0-1.10.41.10.6-1.80.10.6-0.3-0.5-0.0-0.0-0.11.01.00.90.60.0-0.60.6
Patch foraging water rate 24 sec1.52.05.01.62.2-1.9-2.02.0-2.11.42.01.5-1.61.01.2-0.7-0.80.3-0.10.12.12.11.11.0-0.00.2-0.2
Patch foraging water rate 6 sec0.60.94.30.40.9-0.8-0.91.0-0.91.01.10.60.90.40.40.10.1-0.30.6-0.42.12.1-0.11.3-1.01.0-1.0
Seeking ratio, delayed vs. immediate footshock1.72.07.81.41.5-1.4-1.31.3-1.41.21.31.5-2.81.21.7-1.7-1.21.4-1.70.9-0.8-0.81.3-1.31.1-0.91.0
Distance traveled before self-admin1.11.25.0-1.0-0.30.40.3-0.30.3-0.6-0.4-0.42.2-0.0-0.91.10.8-1.01.4-1.11.61.7-1.41.5-1.51.3-1.3
Distance traveled after self-admin0.30.41.5-0.30.4-0.2-0.30.3-0.30.00.20.30.1-0.1-0.10.40.4-0.50.6-0.71.21.2-0.41.0-1.00.8-0.8
Extensor digitorum longus weight1.45.311.2-2.2-1.11.21.5-1.51.6-1.3-1.4-1.42.3-2.3-2.62.83.0-3.13.1-3.22.42.4-2.03.2-3.31.8-1.8
Bone: elastic displacement1.61.87.5-1.6-1.51.81.8-1.71.7-0.7-1.7-0.92.7-0.8-1.41.11.2-0.90.9-0.8-0.4-0.4-1.70.3-1.20.9-0.9
Bone: elastic work1.62.04.71.51.8-1.4-1.41.4-1.42.21.52.1-0.61.81.8-1.9-1.61.7-1.71.3-0.1-0.10.8-1.20.80.3-0.2
Bone: endosteal estimation3.88.216.73.43.6-3.6-3.63.6-3.83.73.64.1-2.73.73.4-3.2-2.32.7-2.41.51.41.51.7-1.11.31.1-1.1
Bone: endosteal perimeter1.73.67.62.32.5-2.5-2.82.7-2.72.42.52.6-1.52.21.9-1.6-1.21.2-0.90.71.91.90.90.10.31.1-1.2
Epididymis fat weight0.71.64.31.50.4-0.6-0.70.7-0.71.30.61.00.72.11.1-1.4-1.72.0-1.62.0-1.3-1.30.5-2.01.8-0.10.1
Delta time in closed arm before/after self-admin0.20.20.80.60.1-0.1-0.30.3-0.30.60.40.30.70.80.5-0.4-0.70.6-0.40.9-0.2-0.2-0.1-0.50.40.1-0.1
Delta time in open arm before/after self-admin0.10.11.6-1.30.2-0.4-0.10.1-0.0-0.2-0.00.2-0.2-0.2-0.0-0.10.4-0.10.0-0.70.40.4-0.00.3-0.5-0.20.2
Diff in mean of infusions in LGA sessions3.23.511.7-1.3-2.92.82.4-2.52.4-1.5-2.5-1.61.7-0.4-1.40.70.80.2-0.30.3-3.4-3.4-1.9-2.00.7-0.20.2
Delay discount exponential model param0.10.11.00.0-0.1-0.1-0.30.3-0.30.50.20.0-1.0-0.20.4-0.30.50.1-0.4-0.2-0.4-0.40.2-0.2-0.1-0.10.1
Extinction: sum of active levers before priming1.81.84.3-1.9-1.21.31.4-1.41.3-0.9-1.4-1.02.1-1.0-1.51.41.6-1.51.4-1.40.50.5-1.51.2-1.60.9-0.9
Active lever presses in extinction session 60.70.63.5-0.9-1.21.00.9-0.90.9-0.6-0.9-0.91.9-0.4-0.80.70.7-0.50.6-0.3-0.2-0.2-1.00.2-0.30.5-0.5
Bone: final force5.89.418.63.94.1-4.1-4.03.9-3.94.13.84.3-2.33.53.4-3.3-2.92.8-2.42.11.61.62.2-1.11.60.8-0.8
Bone: final moment5.99.620.73.94.0-4.0-3.83.8-3.84.23.64.6-2.33.73.5-3.5-2.93.0-2.72.21.21.32.1-1.41.61.0-1.0
Food consumed during 24 hour testing period2.32.87.1-2.1-1.21.31.6-1.51.6-1.5-1.5-0.90.6-1.8-1.71.62.4-2.11.7-2.70.90.9-1.71.8-2.41.3-1.3
Glucose0.40.62.1-0.00.20.10.1-0.10.10.70.10.7-0.70.40.9-1.1-0.71.1-1.40.7-1.4-1.40.2-1.50.8-0.30.3
Heart weight1.21.74.1-1.3-0.60.60.8-0.90.8-1.3-1.0-0.91.9-0.8-1.81.71.2-1.52.0-1.61.51.5-1.01.7-1.50.9-0.9
Delay discount hyperbolic model param0.10.10.7-0.2-0.2-0.0-0.20.2-0.20.50.10.0-0.8-0.20.4-0.30.50.1-0.5-0.2-0.6-0.60.1-0.3-0.1-0.00.0
Intermittent access intake day 1-15 change1.81.85.80.80.2-0.5-0.60.6-0.60.50.60.0-2.40.21.2-1.3-1.11.2-1.71.5-1.8-1.91.7-1.61.6-2.22.1
Intermittent access intake escalation1.61.64.60.5-0.1-0.1-0.10.2-0.20.20.2-0.1-1.80.10.9-1.0-1.11.2-1.51.5-2.1-2.11.3-1.81.6-2.12.1
Intermittent access intake escalation 20.50.41.00.80.1-0.5-0.40.4-0.40.70.40.3-0.50.40.7-0.8-0.70.7-0.91.0-0.8-0.80.7-0.90.8-0.80.8
Intermitt. access day 1 inactive lever presses0.30.31.00.40.4-0.6-0.30.3-0.3-0.40.3-0.1-0.9-0.2-0.30.30.1-0.60.6-0.51.01.00.50.9-0.4-0.20.2
Intermitt. access day 15 inactive lever presses0.50.52.8-0.7-0.60.40.3-0.30.3-0.7-0.4-0.9-1.7-1.3-0.50.40.5-0.60.3-0.3-0.5-0.60.50.2-0.0-1.31.3
Intermitt. access escalation Index1.41.23.41.81.1-1.2-1.61.6-1.61.21.60.8-1.11.41.3-0.8-1.00.9-0.60.90.70.70.8-0.10.80.0-0.0
Intermittent access day 1 total infusions0.40.52.1-1.5-0.30.50.4-0.40.4-0.1-0.50.3-0.0-0.1-0.2-0.01.0-0.2-0.0-1.10.00.1-1.10.1-1.11.3-1.3
Intermittent access day 15 total infusions0.60.73.1-1.2-0.80.70.7-0.70.5-0.4-0.7-0.1-1.5-0.20.2-0.50.40.5-1.0-0.2-1.7-1.7-0.3-1.20.1-0.30.3
Intermittent access terminal intake (last 3 days)0.80.93.5-0.7-0.30.30.2-0.20.20.4-0.30.9-1.20.80.8-1.3-0.01.2-1.70.2-1.9-1.8-0.5-1.80.40.5-0.5
Intermittent access total infusions0.40.51.7-0.8-0.20.30.2-0.20.10.3-0.30.7-0.70.70.5-0.90.10.9-1.2-0.0-1.3-1.2-0.6-1.30.10.6-0.6
Intermittent access day 1 locomotion1.51.65.9-1.9-0.91.31.2-1.21.1-0.6-1.30.41.20.0-0.70.31.5-0.30.1-1.6-0.4-0.3-2.3-0.1-1.52.4-2.4
Intermittent access day 15 total locomotion0.20.20.8-0.9-0.20.30.2-0.20.1-0.2-0.30.3-0.60.1-0.1-0.20.50.1-0.3-0.6-0.4-0.3-0.6-0.3-0.60.7-0.7
Intermittent access total locomotion0.40.51.5-1.0-0.40.60.6-0.60.50.0-0.70.60.20.3-0.0-0.40.50.4-0.6-0.5-0.9-0.9-1.1-0.8-0.51.2-1.2
Intermittent access standard deviation1.01.12.51.20.8-0.9-0.90.9-1.01.61.01.3-0.51.61.3-1.4-1.01.4-1.41.1-0.4-0.40.5-1.10.70.3-0.3
Left kidney weight0.51.33.31.20.4-0.5-0.50.5-0.61.30.71.20.71.81.2-1.4-1.41.8-1.51.7-1.0-1.00.3-1.81.50.1-0.1
Right kidney weight0.72.15.21.11.0-1.3-1.11.1-1.12.31.22.20.12.21.8-2.1-1.02.1-2.01.1-0.7-0.60.2-1.80.91.2-1.1
Cocaine induced anxiety0.80.93.10.80.4-0.4-0.40.4-0.40.70.41.1-0.01.71.1-1.3-0.81.4-1.40.8-1.1-1.0-0.3-1.60.81.0-1.0
Post-drug Anxiety0.20.20.80.40.10.0-0.10.1-0.10.60.10.40.90.90.3-0.4-0.20.4-0.50.4-0.4-0.4-0.5-0.60.10.8-0.8
Baseline Anxiety0.30.42.2-0.6-0.50.40.3-0.30.50.3-0.4-0.51.5-0.8-0.60.60.7-0.80.7-0.30.40.4-0.30.8-0.80.1-0.1
Tail length0.31.12.81.10.7-0.4-0.90.9-0.91.70.81.3-0.11.61.2-1.2-1.01.4-1.31.3-0.7-0.70.2-1.31.20.2-0.3
Length with tail0.41.34.30.20.4-0.3-0.40.4-0.41.10.21.4-1.21.11.2-1.7-0.91.6-2.00.9-1.9-1.80.4-2.11.1-0.30.3
Length without tail0.40.93.2-0.60.3-0.40.1-0.20.20.4-0.31.5-1.50.60.7-1.6-0.31.2-1.7-0.0-1.6-1.60.1-1.80.40.2-0.2
Times rat made contact with spout2.63.07.8-1.9-1.41.41.2-1.21.3-1.0-1.2-0.41.1-1.0-1.41.52.6-1.71.6-2.71.31.4-2.31.8-2.82.4-2.4
Lifetime Intake0.50.51.8-1.1-0.30.40.4-0.40.30.3-0.40.7-0.50.60.4-0.80.30.8-1.1-0.2-1.3-1.3-0.8-1.2-0.10.8-0.8
Liver weight, left0.30.52.00.70.6-0.5-0.30.4-0.41.00.51.4-0.41.10.8-0.9-0.30.7-0.70.10.10.1-0.3-0.5-0.21.1-1.1
Liver weight, right0.20.41.7-0.0-0.20.30.3-0.30.30.3-0.20.9-0.40.60.4-0.60.50.5-0.7-0.6-0.5-0.4-1.0-0.6-0.61.3-1.3
Locomotor activity0.50.83.40.80.8-0.8-0.40.4-0.41.30.41.41.91.30.3-0.6-0.30.5-0.20.20.90.9-0.4-0.1-0.21.7-1.7
Locomotor testing distance0.81.32.81.71.7-1.7-1.21.3-1.31.61.31.50.31.41.0-1.1-1.20.9-0.60.91.01.00.8-0.20.60.5-0.5
Locomotor testing rearing0.71.02.71.61.3-1.1-1.41.4-1.50.91.41.1-0.81.31.1-0.8-0.80.7-0.50.60.90.90.60.10.50.2-0.2
Locomotion in novel chamber0.40.52.6-1.6-0.80.90.7-0.70.8-1.1-0.7-0.60.3-0.8-0.60.60.8-0.50.3-0.7-0.3-0.3-0.70.2-0.30.1-0.1
Locomotion in novel chamber post-restriction0.60.72.80.30.7-0.9-0.50.5-0.40.10.5-0.5-0.1-0.7-0.30.4-0.5-0.70.80.31.21.21.31.10.1-1.71.6
Fecal boli incidents, locomotor time 10.40.42.4-0.20.3-0.3-0.30.3-0.30.80.30.30.90.3-0.10.00.4-0.10.2-0.30.70.7-0.30.4-1.01.5-1.5
Change in fecal boli incidents, locomotor task0.40.41.11.10.7-0.7-0.60.6-0.70.80.70.9-0.80.70.9-0.8-0.50.5-0.80.3-0.1-0.10.2-0.40.50.2-0.2
Time >=10cm from walls, locomotor time 10.10.10.7-0.8-0.20.40.2-0.20.2-0.3-0.3-0.10.5-0.2-0.10.10.20.1-0.0-0.3-0.2-0.2-0.2-0.1-0.30.8-0.8
Bouts of movement, locomotor time 11.82.04.81.40.8-0.9-0.90.9-1.11.70.91.4-0.81.91.5-1.8-1.42.1-2.01.7-1.5-1.50.7-2.21.70.3-0.3
Total resting periods, locomotor time 11.11.33.81.20.4-0.5-0.50.5-0.61.10.50.9-0.41.51.0-1.3-1.21.7-1.51.5-1.5-1.50.5-2.01.50.0-0.0
Rest time, locomotor task time 11.61.73.41.51.3-1.1-1.11.1-1.21.61.11.6-0.61.51.3-1.6-1.61.8-1.61.7-0.8-0.80.9-1.71.50.1-0.1
Distance moved, locomotor task time 10.20.22.8-0.00.3-0.3-0.00.00.1-0.5-0.00.3-1.7-0.40.2-0.4-0.10.1-0.4-0.2-0.4-0.40.5-0.30.4-0.20.2
Vertical activity count, locomotor time 10.20.20.7-0.00.7-0.6-0.40.4-0.40.50.40.8-0.80.20.6-0.6-0.20.3-0.6-0.10.10.10.2-0.20.10.8-0.8
Time >=10cm from walls, locomotor time 20.30.41.31.10.4-0.5-0.30.4-0.30.20.40.31.00.70.10.0-0.40.20.30.11.01.0-0.10.40.11.2-1.2
Bouts of movement, locomotor time 20.30.32.40.1-0.30.0-0.20.2-0.3-0.30.2-0.5-1.6-0.30.2-0.2-0.00.3-0.30.2-0.6-0.60.8-0.30.7-1.21.2
Total resting periods, locomotor time 20.40.42.50.40.1-0.4-0.60.6-0.70.10.6-0.1-1.60.20.6-0.5-0.40.6-0.60.5-0.4-0.41.0-0.40.9-1.01.0
Rest time, locomotor task time 22.22.64.71.81.7-1.7-1.81.8-1.82.01.71.6-0.51.61.7-1.7-2.12.0-1.62.2-0.2-0.31.7-1.41.8-0.70.7
Distance moved, locomotor task time 20.20.32.10.70.3-0.4-0.10.1-0.0-0.30.10.5-1.40.20.4-0.6-0.40.6-0.70.2-0.6-0.60.3-0.80.8-0.10.1
Vertical activity count, locomotor time 20.50.53.30.30.5-0.5-0.40.4-0.20.80.40.90.30.90.5-0.60.30.2-0.3-0.40.50.6-0.80.0-0.51.8-1.8
Light reinforcement 10.50.94.3-0.2-0.50.50.5-0.40.5-0.1-0.3-0.3-0.8-0.30.4-0.6-0.50.7-1.10.9-2.0-2.10.6-1.41.2-1.51.5
Light reinforcement 20.30.42.2-0.1-0.30.40.3-0.30.30.2-0.10.0-0.20.20.4-0.5-0.40.7-0.90.7-1.5-1.50.1-1.20.8-0.70.7
Bone: marrow area3.57.615.63.33.5-3.5-3.53.5-3.63.53.54.0-2.53.63.2-3.0-2.22.6-2.31.41.41.51.6-1.01.21.1-1.1
Bone: maximum diameter1.73.112.31.62.4-2.2-2.42.3-2.31.52.11.5-0.70.80.6-0.1-0.1-0.50.9-0.63.53.50.72.0-1.11.3-1.3
Bone: maximum force8.514.730.54.94.9-4.9-4.64.6-4.55.24.45.5-2.74.64.4-4.4-3.84.0-3.53.01.31.32.6-2.12.21.1-1.1
Bone: maximum moment8.214.131.64.74.7-4.7-4.34.3-4.35.24.25.6-2.64.74.3-4.5-3.84.1-3.62.90.91.02.4-2.32.21.2-1.2
Mean time between licks in bursts0.30.41.3-0.4-1.11.10.8-0.80.7-0.6-0.8-0.70.8-0.0-0.40.50.30.00.10.1-0.9-0.9-0.8-0.40.00.1-0.1
Mean num. licks in bursts0.81.03.0-1.3-0.30.40.8-0.80.8-0.9-0.8-0.20.1-1.1-1.10.91.3-1.31.1-1.70.80.8-0.71.2-1.60.8-0.8
Cd content in liver0.50.51.8-0.20.1-0.20.0-0.0-0.0-0.8-0.1-0.9-0.6-1.0-0.71.00.5-1.21.1-0.71.01.00.41.3-0.5-0.60.6
Co content in liver0.20.20.8-0.7-0.40.50.4-0.40.5-0.3-0.40.0-0.2-0.5-0.20.20.9-0.50.1-0.9-0.00.0-0.70.3-0.80.6-0.6
Cu content in liver1.51.93.7-1.7-1.61.61.7-1.71.6-1.2-1.7-0.41.5-0.7-1.41.11.7-1.00.9-1.7-0.2-0.1-1.90.5-1.61.5-1.5
Fe content in liver0.20.20.4-0.6-0.30.50.4-0.40.4-0.5-0.4-0.40.7-0.5-0.50.50.3-0.50.5-0.40.20.1-0.30.4-0.4-0.00.0
K content in liver0.90.82.7-0.8-1.31.21.3-1.31.3-0.4-1.3-0.31.7-0.1-0.60.10.30.3-0.30.1-1.4-1.4-1.0-0.90.10.4-0.4
Mg content in liver0.20.30.6-0.6-0.70.70.7-0.70.7-0.8-0.7-0.60.3-0.5-0.60.30.3-0.20.2-0.3-0.5-0.5-0.5-0.1-0.1-0.10.2
Mn content in liver1.01.25.8-0.9-1.51.31.3-1.31.3-1.2-1.3-1.62.4-0.9-1.31.30.5-0.81.1-0.1-0.4-0.4-0.60.3-0.1-0.30.3
Na content in liver0.90.94.6-0.4-0.70.70.8-0.80.9-0.5-0.8-0.0-0.10.10.1-0.7-0.61.0-1.10.8-2.1-2.20.0-1.71.1-0.70.7
Rb content in liver1.41.84.8-0.6-0.30.30.3-0.30.3-0.5-0.3-0.11.4-0.6-1.11.41.4-1.41.8-1.72.12.2-1.51.9-2.01.9-1.9
Se content in liver0.40.42.7-0.1-0.10.10.0-0.00.1-0.2-0.1-0.90.5-0.5-0.20.2-0.7-0.0-0.11.0-0.6-0.70.8-0.30.9-1.61.6
Sr content in liver0.30.30.90.60.7-0.8-0.80.8-0.80.90.80.40.10.60.5-0.3-0.30.3-0.10.40.60.60.50.20.1-0.00.0
Zn content in liver1.01.13.0-1.7-1.11.01.2-1.21.3-1.3-1.1-0.6-0.7-1.4-0.90.51.5-1.00.3-1.7-0.5-0.5-0.90.4-1.30.3-0.3
Bone: minimum diameter5.910.927.54.04.2-4.1-4.14.1-4.04.44.05.2-2.44.23.8-3.7-2.53.1-2.71.51.92.11.4-1.10.82.2-2.2
Time in familiar zone, hab. session 11.51.42.81.21.6-1.7-1.51.5-1.51.51.51.7-0.51.11.1-1.0-0.60.7-0.40.11.61.60.40.3-0.31.1-1.1
Time in novel zone, hab. session 10.40.42.0-0.3-0.80.90.7-0.70.7-0.3-0.7-0.30.10.0-0.2-0.00.10.2-0.40.3-1.4-1.4-0.4-0.80.5-0.30.3
Total zone transitions, hab. session 11.62.24.3-2.0-2.02.12.0-2.02.1-1.7-2.1-0.80.4-0.9-1.30.81.7-0.70.3-1.5-1.4-1.3-1.9-0.3-1.10.9-1.0
Total locomotion distance, hab. session 11.42.04.7-1.6-1.61.92.1-2.12.1-1.1-2.2-0.21.2-0.3-1.00.20.90.0-0.3-0.6-2.1-2.1-1.7-1.2-0.40.9-0.9
Locomotion velocity, hab. session 12.23.27.4-2.3-2.22.42.6-2.72.7-1.7-2.7-0.92.1-1.0-1.91.01.6-0.80.6-1.2-1.7-1.6-2.2-0.5-1.01.0-1.1
Time in familiar zone, hab. session 22.12.26.6-2.0-0.70.81.5-1.41.5-1.4-1.3-0.40.3-1.8-1.61.21.9-1.71.4-2.60.91.0-1.41.4-2.41.4-1.3
Time in novel zone, hab. session 21.01.02.71.40.4-0.5-1.21.2-1.21.01.10.3-0.21.51.1-0.7-1.01.1-0.81.6-0.3-0.30.7-0.71.6-0.60.6
Total zone transitions, hab. session 21.41.83.9-1.5-2.01.71.6-1.71.7-0.9-1.7-0.71.9-0.3-1.20.91.6-0.60.6-1.1-0.7-0.6-2.0-0.0-1.11.5-1.4
Total locomotion distance, hab. session 21.72.34.7-2.0-1.71.82.1-2.12.1-1.2-2.1-0.82.2-0.9-1.71.21.6-1.00.9-1.4-0.7-0.6-1.90.2-1.31.1-1.1
Locomotion velocity, hab. session 21.72.35.0-2.0-1.71.82.1-2.12.1-1.2-2.2-0.82.2-0.9-1.71.11.5-1.00.9-1.2-0.8-0.8-1.80.1-1.21.0-1.0
Novel to familiar place preference ratio0.90.92.00.80.6-0.6-0.80.9-0.91.00.90.9-1.00.81.4-1.3-0.91.3-1.41.2-0.8-0.80.7-1.11.3-0.40.4
Novelty place preference0.30.30.90.20.1-0.1-0.40.4-0.40.60.40.5-0.50.30.8-0.8-0.30.8-0.90.7-0.7-0.70.2-0.80.8-0.10.1
Time in novel zone, NPP test0.40.40.90.40.3-0.3-0.60.6-0.60.60.60.4-0.80.30.9-0.8-0.50.8-0.90.8-0.5-0.50.4-0.70.9-0.40.3
Total zone transitions, NPP test2.33.36.2-2.5-2.42.32.5-2.52.5-2.1-2.4-1.51.4-1.6-2.01.62.1-1.41.2-1.9-0.9-0.8-2.00.4-1.50.8-0.8
Total locomotion distance, NPP test2.94.08.2-2.7-2.32.52.8-2.82.8-2.1-2.9-1.22.0-1.5-2.31.62.1-1.51.2-2.0-1.0-1.0-2.30.3-1.61.2-1.2
Locomotion velocity, NPP test3.14.49.4-2.9-2.42.73.0-3.03.0-2.2-3.1-1.32.1-1.6-2.41.62.0-1.41.2-1.9-1.4-1.3-2.40.1-1.51.0-1.1
Intraocular pressure1.82.48.4-1.2-0.30.4-0.10.0-0.1-1.4-0.2-1.40.1-1.5-1.41.91.9-2.32.3-2.22.62.6-0.62.9-2.00.3-0.3
Delta distance traveled before/after self-admin0.70.88.10.20.6-0.3-0.30.3-0.40.20.40.3-2.8-1.00.5-0.5-0.30.1-0.60.2-0.6-0.71.3-0.40.5-1.41.4
Delta ambulatory time before/after self-admin0.60.77.3-0.40.3-0.1-0.10.1-0.10.10.20.0-2.7-1.20.3-0.30.2-0.2-0.5-0.2-0.6-0.71.1-0.10.2-1.51.5
Parametrial fat weight2.14.08.72.72.2-2.7-2.72.7-2.71.62.71.2-2.91.82.2-1.7-1.91.5-1.31.60.80.82.5-0.41.7-1.41.3
Pavlov. Cond. lever latency0.10.10.30.40.2-0.1-0.10.1-0.20.10.10.0-0.50.20.2-0.3-0.40.2-0.30.4-0.3-0.30.3-0.30.5-0.30.3
Pavlov. Cond. magazine entry latency0.30.31.3-0.4-0.20.20.2-0.20.2-0.2-0.2-0.21.1-0.3-0.50.70.6-0.60.8-0.60.80.8-0.50.8-0.70.6-0.6
Pavlov. Cond. change in total contacts0.10.10.5-0.7-0.30.40.4-0.40.4-0.6-0.4-0.30.3-0.6-0.50.40.2-0.40.3-0.3-0.1-0.1-0.10.1-0.2-0.20.2
Pavlov. Cond. index score0.10.11.3-0.4-0.40.30.3-0.30.4-0.1-0.3-0.21.1-0.1-0.40.40.3-0.30.4-0.10.10.1-0.40.2-0.30.3-0.3
Pavlov. Cond. latency score0.10.10.8-0.2-0.20.10.1-0.10.10.1-0.10.00.9-0.0-0.20.30.2-0.20.3-0.20.40.4-0.30.3-0.30.3-0.3
Pavlov. Cond. lever contacts0.30.41.0-1.0-0.80.70.8-0.80.8-0.7-0.8-0.61.0-0.7-0.80.60.5-0.50.5-0.5-0.3-0.3-0.50.1-0.4-0.00.0
Pavlov. Cond. magazine entry number0.70.92.11.00.7-0.8-0.80.8-0.80.80.80.7-1.50.81.1-1.2-1.11.1-1.31.0-0.7-0.70.9-1.01.1-0.60.6
Pavlov. Cond. intertrial magazine entries0.30.42.3-0.3-0.60.70.5-0.50.5-0.2-0.4-0.2-0.30.00.3-0.4-0.00.5-0.80.4-1.5-1.5-0.3-1.10.6-0.20.2
Pavlov. Cond. lever-magazine prob. diff.0.10.11.0-0.5-0.60.50.5-0.50.5-0.3-0.5-0.31.0-0.2-0.40.30.2-0.10.2-0.0-0.3-0.3-0.3-0.1-0.10.1-0.1
Pavlov. Cond. response bias0.91.13.2-1.4-1.21.11.2-1.21.2-1.1-1.2-1.01.8-0.9-1.31.21.1-1.01.1-0.90.10.1-1.00.6-0.90.4-0.4
Pavlov. Cond. lever latency1.01.33.31.21.1-1.0-0.90.9-0.90.80.80.6-1.00.81.1-1.1-1.71.2-1.21.7-0.9-0.91.5-1.21.8-1.31.3
Pavlov. Cond. magazine entry latency3.74.39.7-2.3-1.11.31.5-1.51.5-2.2-1.6-2.10.7-2.9-2.62.82.2-3.13.0-2.71.81.8-0.93.0-2.50.1-0.1
Pavlov. Cond. change in total contacts1.62.25.0-1.3-1.01.00.8-0.80.8-1.0-0.7-0.91.2-1.2-1.41.71.9-1.82.0-2.11.71.7-1.52.1-2.21.3-1.3
Pavlov. Cond. index score2.53.36.3-2.0-1.41.41.4-1.41.4-1.8-1.4-1.71.0-2.1-2.12.32.2-2.52.5-2.41.51.5-1.32.4-2.40.6-0.6
Pavlov. Cond. latency score3.24.07.6-2.1-1.41.41.4-1.41.4-1.8-1.4-1.71.2-2.2-2.32.52.5-2.82.7-2.71.81.8-1.52.7-2.71.0-1.0
Pavlov. Cond. lever contacts0.81.12.6-1.1-1.01.00.8-0.80.8-1.0-0.8-0.70.6-0.9-1.01.11.5-1.21.2-1.60.70.8-1.31.2-1.60.9-0.9
Pavlov. Cond. magazine entry number3.54.39.72.31.0-1.2-1.41.4-1.42.21.41.9-0.52.82.5-2.7-2.33.1-3.02.9-2.0-2.01.0-3.02.6-0.30.3
Pavlov. Cond. intertrial magazine entries6.28.116.93.22.0-2.1-2.32.3-2.33.42.43.3-1.53.83.6-3.9-3.04.1-4.03.3-2.0-2.01.4-3.73.00.1-0.1
Pavlov. Cond. lever-magazine prob. diff.2.93.67.1-2.1-1.51.51.5-1.51.5-2.0-1.5-1.81.1-2.3-2.32.52.3-2.72.6-2.51.51.5-1.42.5-2.40.6-0.6
Pavlov. Cond. response bias1.31.84.0-1.6-1.11.21.0-1.01.0-1.7-1.0-1.3-0.0-1.7-1.51.61.7-1.81.6-2.00.90.9-0.91.7-1.70.2-0.2
Time in closed arm before self-admin0.60.72.30.20.3-0.20.0-0.0-0.1-0.8-0.1-0.5-1.3-1.3-0.80.8-0.3-0.81.1-0.00.90.81.21.10.0-1.51.5
Time in closed arm after self-admin0.50.51.81.30.6-0.4-0.60.6-0.7-0.10.5-0.4-0.2-0.2-0.10.5-0.9-0.20.80.91.11.01.10.80.5-0.90.9
Time in open arm before self-admin0.50.62.00.7-0.1-0.1-0.50.5-0.40.90.50.1-1.40.20.8-0.8-0.20.8-1.10.6-1.2-1.20.6-0.90.7-0.80.8
Time in open arm after self-admin0.20.31.0-0.7-0.2-0.3-0.10.2-0.10.40.20.5-1.00.40.5-0.80.40.5-0.9-0.3-0.8-0.7-0.2-0.7-0.2-0.20.2
Bone: periosteal estimation6.012.424.74.34.8-4.7-4.74.7-4.74.74.65.0-2.54.13.8-3.4-2.72.8-2.21.72.82.92.1-0.51.01.7-1.7
Bone: periosteal perimeter2.84.610.12.63.0-2.9-3.23.1-3.12.62.82.7-1.52.21.9-1.5-1.21.1-0.60.62.62.61.20.60.11.2-1.2
Bone: post-yield work4.05.410.63.23.0-3.3-3.03.0-2.92.62.92.7-2.72.32.7-2.4-2.42.0-1.91.70.90.92.2-0.91.5-0.10.1
Progressive ratio test 1 active lever presses1.21.23.8-0.40.2-0.10.2-0.20.20.9-0.11.7-0.21.41.0-1.6-0.31.6-1.80.2-1.5-1.4-0.9-1.90.11.6-1.6
Progressive ratio test 1 breakpoint1.41.54.4-0.40.1-0.10.2-0.20.11.1-0.11.8-0.21.61.1-1.8-0.21.7-2.00.2-1.7-1.5-1.0-2.10.11.8-1.8
Progressive ratio test 1 inactive lever presses0.20.31.5-0.70.1-0.20.1-0.10.10.4-0.10.8-1.2-0.00.3-0.70.30.3-0.8-0.4-0.7-0.6-0.1-0.6-0.40.4-0.4
Progressive ratio test 2 active lever presses0.50.51.8-1.3-0.30.40.6-0.60.50.2-0.50.6-0.7-0.10.3-0.70.50.4-1.0-0.6-1.3-1.2-0.6-0.9-0.40.6-0.6
Progressive ratio test 2 breakpoint0.40.41.2-1.0-0.10.20.4-0.40.30.5-0.30.8-0.40.20.5-0.90.40.6-1.1-0.4-1.1-1.0-0.6-1.0-0.40.8-0.8
Progressive ratio test 2 inactive lever presses0.30.43.1-0.20.5-0.5-0.30.3-0.30.50.40.7-1.8-0.00.7-0.8-0.30.6-0.90.1-0.5-0.50.5-0.60.2-0.30.3
Incentive Sensitization - Responses0.20.21.1-0.8-0.20.10.0-0.0-0.00.1-0.00.3-0.9-0.00.1-0.20.9-0.2-0.2-1.0-0.00.0-0.60.2-0.80.7-0.7
Incentive Sensitization - Breakpoint0.20.20.9-0.7-0.20.20.0-0.1-0.00.1-0.10.4-0.70.10.1-0.20.9-0.2-0.2-1.0-0.1-0.0-0.70.1-0.80.9-0.9
Sum of active levers in priming session hrs 5-60.40.45.4-0.1-0.00.20.5-0.50.50.5-0.40.52.30.5-0.1-0.1-0.50.3-0.10.7-0.3-0.3-0.6-0.60.30.8-0.8
Progressive ratio0.30.41.70.90.5-0.2-0.10.2-0.10.40.21.00.31.30.5-0.7-0.80.8-0.70.6-0.4-0.3-0.4-0.90.60.7-0.9
Food seeking constrained by brief footshock0.70.84.91.30.1-0.4-0.30.3-0.20.40.3-0.02.20.7-0.20.5-0.3-0.30.90.31.51.6-0.50.9-0.41.3-1.5
Seeking ratio, punishment vs. effort0.30.41.3-0.3-0.50.20.1-0.10.1-0.3-0.2-0.90.8-0.9-0.60.90.6-0.91.0-0.40.90.90.11.1-0.70.10.1
Retroperitoneal fat weight1.54.810.33.22.7-2.8-2.92.9-2.92.72.82.4-1.33.12.4-2.1-2.22.2-1.61.91.11.11.6-0.81.50.3-0.3
Reaction time number correct0.10.20.7-0.10.1-0.0-0.10.1-0.20.80.10.60.40.60.5-0.7-0.10.7-0.70.5-0.6-0.5-0.2-0.70.30.3-0.3
Reaction time mean minus median0.60.81.71.21.1-0.8-1.00.9-0.91.00.80.9-0.21.00.9-0.8-1.31.0-0.71.30.00.00.7-0.61.1-0.40.4
Reaction time mean minus median AUC1.72.24.21.81.9-1.5-1.81.8-1.82.11.71.8-0.71.81.8-1.6-1.81.7-1.41.80.20.21.0-1.01.3-0.10.1
Reaction time num false alarms0.50.61.4-0.8-1.20.91.1-1.11.1-0.7-1.0-0.70.6-0.6-0.80.61.0-0.70.4-0.8-0.5-0.4-1.00.1-0.70.5-0.5
Reaction time num false alarms AUC0.50.71.3-0.9-1.00.81.1-1.11.1-1.1-1.0-1.00.3-1.0-1.00.81.0-1.00.8-0.9-0.1-0.1-0.60.5-0.70.1-0.1
Reaction time trials correct on left0.10.20.7-0.10.1-0.0-0.10.1-0.20.80.10.60.40.60.5-0.7-0.10.7-0.70.5-0.6-0.5-0.2-0.70.30.3-0.3
Reaction time trials on left0.20.30.8-0.00.1-0.1-0.20.2-0.20.90.10.70.40.70.5-0.8-0.20.8-0.80.5-0.6-0.6-0.1-0.80.40.3-0.3
Reaction time mean1.11.53.61.51.5-1.3-1.01.0-1.01.60.91.9-0.21.71.3-1.6-1.61.6-1.51.4-0.4-0.40.7-1.41.10.3-0.3
Reaction time mean AUC1.21.73.41.41.3-1.1-0.80.8-0.81.60.81.80.01.81.4-1.7-1.71.8-1.71.7-0.8-0.80.6-1.71.30.3-0.3
Median of all reaction times0.91.33.31.31.3-1.2-0.70.7-0.71.50.81.8-0.01.61.2-1.6-1.41.5-1.51.2-0.6-0.50.5-1.41.00.5-0.5
Reaction time omissions0.40.61.81.10.8-0.6-0.60.6-0.60.80.61.2-0.11.30.8-0.9-1.00.9-0.80.8-0.0-0.0-0.0-0.70.60.6-0.6
Reaction time false alarm rate0.30.51.3-0.4-0.60.40.8-0.80.8-1.1-0.7-1.0-0.3-1.0-0.80.80.6-0.90.8-0.80.10.1-0.10.6-0.5-0.40.4
Reaction time premature initiation rate0.50.71.91.31.4-1.0-1.11.1-1.10.71.20.7-0.20.40.5-0.2-1.10.10.10.71.11.10.90.40.5-0.40.4
Reaction time premature initiations0.60.91.91.41.4-1.0-1.11.2-1.21.31.31.20.11.00.9-0.8-1.30.8-0.61.10.60.50.7-0.30.8-0.10.1
Std. dev. reaction times1.21.73.41.81.8-1.5-1.51.4-1.51.41.31.5-0.91.51.3-1.3-1.81.3-1.11.60.20.21.2-0.81.3-0.50.4
Reaction time trials completed0.20.30.8-0.00.1-0.1-0.20.2-0.20.90.10.70.40.70.5-0.8-0.20.8-0.80.5-0.6-0.6-0.1-0.80.40.3-0.3
Reaction time trials AUC0.30.41.30.20.4-0.4-0.50.5-0.51.20.40.90.20.80.7-0.9-0.30.8-0.90.6-0.3-0.3-0.0-0.70.30.4-0.4
Run reversals in cocaine runway, females0.60.62.4-0.3-0.70.50.6-0.60.6-0.6-0.7-0.51.5-0.2-1.00.80.7-0.81.0-0.60.60.7-0.90.7-0.81.0-1.0
Run reversals in cocaine runway, males3.63.56.5-2.4-2.52.52.0-2.12.1-1.8-2.2-2.12.4-1.7-2.22.02.2-1.81.7-1.6-0.3-0.3-2.11.0-1.61.1-0.8
Latency to leave start box in cocaine runway0.80.92.80.00.1-0.10.0-0.0-0.10.3-0.00.2-0.20.20.5-0.8-1.01.1-1.11.3-1.6-1.71.0-1.61.4-1.71.5
Latency to leave start box in cocaine runway, F0.50.62.3-0.2-0.10.10.3-0.30.30.2-0.30.00.3-0.10.2-0.6-0.60.8-0.90.9-1.5-1.50.6-1.31.0-1.11.1
Latency to leave start box in cocaine runway, M0.20.20.90.30.4-0.4-0.40.4-0.50.30.30.50.80.90.1-0.1-0.40.30.10.30.70.7-0.20.1-0.00.4-0.6
Std. dev. time between licks in bursts0.50.61.90.4-0.20.20.1-0.10.10.2-0.1-0.30.10.30.4-0.4-0.90.7-0.71.4-1.3-1.40.5-1.11.3-1.21.2
Total sessions with >9 infusions0.91.03.7-1.1-0.20.40.4-0.40.30.6-0.51.30.61.30.4-1.00.41.0-1.2-0.3-1.2-1.1-1.4-1.4-0.41.9-1.9
Short access day 1 total inactive lever presses0.50.52.20.20.7-0.30.0-0.00.0-0.00.00.60.20.0-0.50.50.1-0.70.9-0.71.51.5-0.41.1-1.01.1-1.1
Short access day 10 total inactive lever presses1.41.62.9-1.5-1.41.31.6-1.61.6-1.6-1.6-1.41.0-1.5-1.71.41.2-1.51.4-1.2-0.1-0.1-0.60.9-1.0-0.40.4
Short access day 1 total infusions0.70.73.1-0.21.0-0.8-0.60.6-0.61.10.61.60.01.20.7-0.90.00.6-0.6-0.50.70.7-0.5-0.1-0.71.8-1.7
Short access day 10 total infusions0.70.82.6-1.4-1.01.31.2-1.31.2-0.6-1.3-0.20.1-0.3-0.50.00.50.1-0.4-0.3-1.6-1.6-1.0-1.0-0.20.3-0.3
Short access total infusions0.50.51.3-1.1-0.10.30.3-0.40.30.5-0.41.0-0.20.60.4-0.90.30.8-1.1-0.3-1.1-1.1-0.8-1.1-0.31.1-1.1
Short access day 1 locomotion1.61.78.1-1.8-0.40.60.7-0.70.8-0.2-0.80.71.80.2-0.50.31.4-0.40.5-1.70.80.9-2.10.5-2.02.9-2.8
Short access day 10 total locomotion1.31.47.8-0.2-0.50.70.6-0.70.60.7-0.71.02.81.3-0.2-0.30.30.6-0.3-0.1-0.4-0.3-2.0-0.8-0.62.7-2.7
Short access total locomotion0.80.82.3-1.2-0.71.01.1-1.11.0-0.0-1.10.41.40.0-0.5-0.00.70.1-0.3-0.5-1.0-0.9-1.5-0.7-0.71.5-1.5
One hour access (0.3 mA shock)0.60.72.3-1.5-1.11.11.1-1.11.1-1.1-1.0-0.60.0-0.6-0.60.30.8-0.30.0-0.7-1.0-1.0-0.8-0.3-0.50.1-0.1
Compulsive drug intake0.40.41.1-0.1-0.30.50.2-0.20.2-0.9-0.1-1.00.5-0.5-0.61.00.2-0.81.0-0.20.60.60.21.0-0.0-0.90.9
One hour access (shock baseline)0.30.31.2-0.7-0.20.20.2-0.20.20.1-0.30.4-0.80.20.4-0.70.00.7-0.90.0-1.1-1.1-0.3-1.00.10.3-0.3
Social response proportion1.81.98.2-0.6-1.21.00.9-0.90.9-0.3-0.8-0.72.9-0.0-1.11.21.4-1.11.4-1.21.21.3-1.91.3-1.62.3-2.3
Social responses0.91.23.0-0.9-1.71.31.2-1.21.2-1.1-1.2-1.61.7-1.0-1.31.40.9-1.11.2-0.5-0.1-0.1-0.80.6-0.4-0.00.0
Social time0.20.22.00.0-0.80.30.4-0.40.4-0.3-0.4-0.91.4-0.3-0.50.7-0.0-0.30.60.4-0.0-0.0-0.00.20.1-0.30.3
Soleus weight1.85.111.73.03.4-3.4-3.13.1-3.02.63.32.3-2.61.62.5-1.9-2.01.2-1.31.21.81.82.20.00.8-0.10.1
Bone: stiffness7.712.120.84.54.4-4.6-4.44.3-4.34.14.14.4-3.63.93.9-3.8-3.53.4-3.02.71.11.22.9-1.72.40.2-0.2
Tibialis anterior weight0.41.54.51.11.6-1.5-1.41.4-1.42.11.52.1-0.71.31.3-1.2-0.20.8-0.9-0.11.01.00.1-0.1-0.31.4-1.4
Time to tail flick, vehicle, before self-admin0.60.63.7-0.3-0.71.00.8-0.80.9-0.3-0.8-0.11.90.4-0.40.10.10.3-0.20.2-1.0-0.9-1.2-0.80.11.2-1.2
Time to tail flick, vehicle, after self-admin1.11.23.6-0.6-1.61.91.3-1.31.3-1.0-1.5-1.61.2-1.0-1.21.10.5-0.50.60.3-1.3-1.3-0.6-0.30.2-0.70.7
Time to tail flick, test, before self-admin0.20.20.5-0.5-0.30.40.5-0.50.50.1-0.4-0.10.7-0.4-0.3-0.0-0.10.1-0.20.2-0.7-0.7-0.1-0.50.1-0.40.4
Time to tail flick, test, after self-admin0.40.42.40.1-0.40.50.5-0.50.4-0.1-0.50.0-0.20.1-0.0-0.4-0.30.7-0.70.5-1.5-1.50.1-1.30.8-0.20.2
Delta time to tail flick, vehicle, before/after SA0.30.30.7-0.0-0.60.70.5-0.50.5-0.5-0.6-0.7-0.8-0.8-0.50.40.3-0.30.20.1-0.8-0.80.3-0.20.2-0.80.8
Delta time to tail flick, test, before/after SA0.20.10.60.80.1-0.2-0.30.3-0.40.20.20.2-0.00.80.2-0.1-0.10.3-0.10.20.20.2-0.3-0.10.10.8-0.8
Tibia length0.20.61.8-0.3-0.80.80.7-0.70.6-1.0-0.8-0.9-0.3-0.5-0.40.3-0.4-0.0-0.10.5-1.3-1.40.4-0.60.8-1.21.3
Ambulatory time before self-admin0.91.05.7-0.5-0.00.10.0-0.00.1-0.3-0.1-0.32.40.2-0.60.90.5-0.81.3-0.71.71.8-1.01.4-1.21.1-1.1
Ambulatory time after self-admin0.70.82.5-1.1-0.10.30.2-0.20.2-0.3-0.2-0.40.6-0.8-0.60.91.1-1.21.2-1.21.41.4-0.81.6-1.50.5-0.5
Bone: tissue strength0.70.71.80.90.9-0.8-0.80.8-0.71.20.61.30.11.20.8-1.1-1.11.2-0.91.0-0.1-0.10.3-0.90.60.3-0.3
Total heroin consumption0.60.76.3-1.0-0.70.80.9-0.90.9-0.0-0.9-0.02.50.7-0.40.00.20.3-0.20.2-0.9-0.9-1.4-0.90.20.7-0.7
Bone: trabecular number3.14.99.42.83.0-3.1-2.72.8-2.72.02.91.7-2.41.52.3-2.0-2.81.7-1.52.20.80.73.0-0.71.9-1.51.6
Bone: trabecular spacing0.81.15.0-0.8-1.11.10.7-0.80.7-0.0-0.90.3-0.70.50.4-0.90.31.1-1.40.3-2.2-2.2-0.9-1.80.70.2-0.2
Bone: trabecular thickness0.30.41.40.61.0-1.0-0.70.7-0.60.10.80.2-0.2-0.30.00.2-0.5-0.30.50.01.21.20.90.7-0.2-0.30.3
Bone: trabecular tissue density0.10.21.70.30.5-0.5-0.40.4-0.40.40.40.3-1.3-0.20.4-0.3-0.20.1-0.20.00.20.20.50.1-0.0-0.20.2
Water consumed over 24 hours1.51.84.8-1.0-0.40.50.6-0.60.7-0.7-0.6-0.81.3-1.2-1.31.71.5-1.82.0-1.72.02.0-1.02.2-2.01.0-1.0
Number of responses in last shaping day0.70.73.2-1.1-0.40.70.9-0.90.8-0.1-0.70.90.70.4-0.1-0.20.60.3-0.3-0.8-0.5-0.4-1.5-0.6-0.81.8-1.8