Erbin

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Erbin 0.01 0.01 6.6e-03 0.01 0.01 0.01 0 2.2e-02 2.1e-02 1.9e-02 5.5e-02
2 pVTA intron excision ratio chr2_36671786_36675214 0.04 0.05 7.6e-03 0.02 0 0.02 0 9.2e-03 2.3e-01 1.1e-02 1.9e-01
3 Brain intron excision ratio chr2_36666462_36675214 0.03 0.03 7.2e-04 0.03 0.03 0.02 0.03 2.0e-03 1.2e-03 4.1e-03 1.5e-03
4 pVTA mRNA stability Erbin 0.04 0.04 7.0e-04 0.03 0.02 0.03 0.01 3.0e-03 1.8e-02 2.9e-03 4.2e-02
5 Eye isoform ratio XM_039103490.2 0.41 0.24 1.3e-03 0.16 0.12 0.26 0.14 2.2e-03 7.5e-03 7.0e-05 3.9e-03
6 Brain mRNA stability Erbin 0.07 0.05 1.8e-07 0.07 0.08 0.07 0.07 2.9e-07 1.5e-07 1.9e-07 2.1e-07
7 pVTA gene expression Erbin 0.03 0.03 4.5e-03 0.02 0.02 0.01 0.01 8.8e-03 1.6e-02 7.7e-02 1.0e-01
8 Adipose mRNA stability Erbin 0.03 0.03 2.6e-03 0.01 0 0 0 3.8e-02 9.3e-02 8.2e-02 1.2e-01
9 OFC gene expression Erbin 0.15 0.11 3.0e-03 0.06 0 0.03 0.05 2.0e-02 3.1e-01 7.0e-02 2.2e-02
10 NAcc intron excision ratio chr2_36671786_36675214 0.02 0.02 3.7e-03 0.01 0.01 0.01 0.01 1.2e-02 3.1e-02 2.3e-02 4.1e-02
11 NAcc gene expression Erbin 0.06 0.05 2.7e-09 0.06 0.05 0.06 0.06 2.9e-09 1.5e-08 5.3e-09 5.0e-09
12 pVTA intron excision ratio chr2_36666462_36669384 0.03 0.04 7.8e-03 0.02 -0 0 -0 5.8e-03 8.8e-01 2.7e-01 9.1e-01
13 pVTA alternative TSS XM_039103491.2 0.03 0.03 7.7e-03 0 0 -0 0.03 2.4e-01 3.1e-01 8.5e-01 1.8e-03
14 IC alternative TSS XM_039103491.2 0.57 0 6.8e-03 0 -0 -0.01 -0 2.2e-01 3.7e-01 7.5e-01 3.4e-01
15 Liver gene expression Erbin 0.29 0.15 0.0e+00 0.2 0.2 0.2 0.2 1.2e-21 7.5e-22 1.1e-21 1.1e-21
16 Liver isoform ratio NM_001427815.1 0.05 0.07 3.5e-03 0.03 0.02 0.02 0.02 5.6e-04 4.2e-03 2.5e-03 1.2e-03
17 Liver isoform ratio XM_063282247.1 0.27 0.21 9.0e-04 0.03 0.02 0.02 0.02 8.2e-04 1.2e-03 1.3e-03 2.2e-03
18 PL gene expression Erbin 0.08 0.09 5.6e-03 0.02 0.02 0.01 0.01 5.8e-03 4.8e-03 2.4e-02 1.1e-02
19 Brain gene expression Erbin 0.21 0.18 3.5e-03 0.03 0.03 0.04 0.03 5.4e-04 9.4e-04 5.4e-05 6.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.71.21.6-1.11.0-1.0-1.01.1-1.0-1.1-1.0-1.11.3-1.01.0-1.01.21.0-1.21.2-0.9-1.3
Area under the delay curve0.30.42.40.6-0.80.40.1-0.80.40.8-0.10.2-0.90.00.10.1-1.00.1-0.10.1-0.5-1.6
BMI with tail2.27.78.9-2.82.6-2.8-2.92.7-2.8-2.6-3.0-2.92.8-2.82.9-2.82.72.9-2.82.8-2.9-2.6
BMI without tail0.51.54.7-1.00.8-1.1-1.31.0-1.2-1.0-1.4-1.21.2-1.11.2-1.21.01.3-1.31.3-1.3-2.2
Body weight3.213.916.94.0-4.13.93.8-4.03.94.03.63.8-3.93.8-3.73.7-3.8-3.73.7-3.73.41.0
Weight adjusted by age0.00.10.20.0-0.20.20.30.10.2-0.00.40.3-0.30.4-0.40.40.1-0.30.2-0.20.30.3
Bone surface0.00.10.8-0.1-0.1-0.1-0.00.0-0.1-0.0-0.2-0.10.1-0.20.1-0.20.20.2-0.30.3-0.2-0.9
Bone volume0.10.21.4-0.30.2-0.3-0.30.3-0.3-0.3-0.3-0.30.4-0.40.3-0.40.40.3-0.50.5-0.4-1.2
Breakpoint value in progressive ratio session3.23.94.4-2.01.9-2.0-2.01.9-2.0-2.0-2.0-2.01.9-2.12.0-2.11.92.0-2.02.0-2.1-1.7
Number of licking bursts2.23.64.1-1.91.9-1.9-1.91.9-1.9-1.9-1.9-1.91.7-1.91.8-1.91.91.9-2.02.0-1.8-2.0
Context. condit. distance diff. score1.21.42.51.4-1.61.31.1-1.51.21.50.91.3-1.51.0-1.01.0-1.4-0.90.6-0.60.7-1.3
Locomotion velocity, session 10.30.30.70.5-0.60.50.4-0.50.50.50.50.6-0.50.5-0.60.5-0.5-0.50.8-0.80.50.9
Locomotion distance, session 10.60.71.41.0-1.10.90.9-0.90.90.90.91.2-1.00.7-0.80.7-0.9-0.70.7-0.70.6-0.1
Locomotion velocity, session 24.55.36.52.3-2.22.32.2-2.22.32.22.32.5-2.02.3-2.32.3-2.1-2.32.6-2.62.32.3
Locomotion distance, session 20.50.71.21.1-1.10.90.8-1.00.91.00.81.0-0.90.8-0.70.8-1.0-0.70.8-0.80.6-0.1
Locomotion velocity, session 34.04.66.02.3-2.32.32.4-2.22.32.22.42.5-2.42.1-2.22.1-2.2-2.11.8-1.82.0-0.1
Locomotion distance, session 35.96.58.02.8-2.82.72.8-2.82.72.82.72.8-2.72.6-2.52.6-2.8-2.42.0-2.02.2-0.8
Stereotopy head waving bouts, day 30.60.72.70.6-0.40.60.8-0.40.60.40.91.0-0.40.7-0.80.7-0.3-0.81.1-1.11.01.6
Stereotopy head waving duration, day 30.10.11.4-0.20.3-0.10.10.2-0.1-0.30.20.10.30.1-0.20.10.3-0.20.4-0.40.41.2
Locomotion velocity, session 70.10.10.20.3-0.20.30.4-0.10.30.10.40.5-0.30.3-0.20.3-0.3-0.30.2-0.20.40.4
Locomotion distance, session 70.30.30.60.7-0.60.60.7-0.60.60.60.50.8-0.80.6-0.50.6-0.8-0.50.3-0.30.5-0.1
Stereotopy head waving bouts, day 70.10.10.3-0.00.20.00.20.20.1-0.20.50.30.20.3-0.30.30.3-0.30.1-0.10.50.1
Stereotopy head waving duration, day 70.20.20.70.4-0.20.40.6-0.20.40.20.80.6-0.10.6-0.60.6-0.1-0.60.4-0.40.80.3
Locomotion velocity, session 82.32.83.21.7-1.71.71.5-1.61.71.61.51.7-1.71.8-1.81.8-1.6-1.81.7-1.71.81.1
Locomotion distance, session 83.24.67.22.6-2.72.32.2-2.62.32.61.92.4-2.52.0-2.02.0-2.5-1.91.7-1.71.5-0.8
Degree of sensitization distance2.72.73.7-1.81.9-1.8-1.81.9-1.7-1.9-1.7-1.71.8-1.51.6-1.51.81.5-1.31.3-1.21.2
Degree of sensitization stereotypy0.10.10.6-0.20.2-0.10.00.3-0.1-0.30.30.10.30.1-0.10.10.4-0.0-0.30.30.2-0.8
Conditioned locomotion0.00.00.0-0.00.2-0.00.10.0-0.0-0.0-0.1-0.10.10.00.00.00.00.0-0.20.2-0.0-0.2
Cocaine response after cond. corrected1.51.82.61.5-1.31.41.4-1.41.41.41.31.3-1.51.4-1.41.4-1.6-1.41.2-1.21.20.5
Cocaine response after cond. not corrected1.92.33.21.7-1.61.61.6-1.71.61.61.51.6-1.81.4-1.51.4-1.8-1.41.3-1.31.20.2
Cocaine response before conditioning0.20.20.50.6-0.70.50.5-0.60.50.60.50.7-0.60.4-0.30.4-0.4-0.40.4-0.40.3-0.3
Saline control response1.11.41.91.3-1.41.31.2-1.31.31.31.31.2-1.31.2-1.31.2-1.3-1.21.0-1.01.20.1
Bone: connectivity density0.10.10.2-0.30.2-0.3-0.20.3-0.3-0.3-0.2-0.30.4-0.30.3-0.30.40.2-0.50.5-0.2-0.4
Bone: cortical apparent density0.00.00.10.2-0.10.10.2-0.10.10.10.20.2-0.30.1-0.20.1-0.2-0.20.1-0.10.20.3
Bone: cortical area0.30.41.10.5-0.40.60.6-0.40.60.40.70.5-0.40.7-0.70.7-0.4-0.70.7-0.70.81.0
Bone: cortical porosity1.71.83.1-1.61.7-1.4-1.51.7-1.4-1.7-1.0-1.21.7-1.01.2-1.01.81.0-0.90.9-0.71.2
Bone: cortical porosity1.61.73.2-1.51.7-1.4-1.41.6-1.4-1.7-1.0-1.11.7-1.01.1-1.01.81.0-0.80.8-0.71.4
Bone: cortical thickness0.30.41.70.4-0.20.50.7-0.20.50.20.80.6-0.40.7-0.70.7-0.2-0.70.6-0.60.91.3
Bone: cortical thickness1.11.21.61.0-1.21.20.9-1.21.21.21.10.8-1.01.1-1.11.1-1.3-1.11.2-1.21.00.9
Bone: cortical tissue density0.00.00.10.2-0.10.20.2-0.10.20.10.20.2-0.30.2-0.30.2-0.2-0.20.1-0.10.30.3
Condit. Reinf. active minus inactive responses1.01.12.3-1.21.5-1.2-0.91.4-1.1-1.4-0.7-0.81.3-0.80.9-0.81.30.8-1.11.1-0.5-0.2
Condit. Reinf. active-inactive response ratio1.11.22.4-1.21.6-1.2-0.81.4-1.2-1.4-0.8-0.81.3-0.90.9-0.91.30.9-1.21.2-0.6-0.6
Condit. Reinf. active responses0.10.10.4-0.40.6-0.4-0.10.5-0.3-0.5-0.0-0.10.4-0.10.2-0.10.40.1-0.40.40.1-0.1
Condit. Reinf. inactive responses1.01.21.61.2-1.31.11.1-1.21.11.21.11.0-1.21.0-1.11.0-1.2-1.01.2-1.20.90.8
Incentive salience index mean0.81.01.7-1.11.3-1.0-0.81.2-1.0-1.2-0.7-0.81.2-0.80.9-0.81.10.8-1.11.1-0.6-0.8
Condit. Reinf. lever presses0.20.31.3-0.50.5-0.5-0.50.5-0.5-0.5-0.4-0.60.6-0.50.5-0.50.40.5-0.70.7-0.5-1.1
Condit. Reinf. active minus inactive responses3.95.05.62.3-2.32.32.2-2.32.32.32.32.2-2.42.3-2.32.3-2.3-2.32.2-2.22.31.1
Condit. Reinf. active-inactive response ratio2.53.04.11.6-1.41.71.7-1.61.71.51.71.6-1.61.9-1.91.9-1.5-1.91.7-1.72.01.6
Condit. Reinf. active responses1.31.92.11.4-1.41.41.3-1.41.41.41.31.4-1.51.4-1.41.4-1.3-1.41.4-1.41.40.6
Condit. Reinf. inactive responses0.00.10.20.3-0.40.20.2-0.30.20.30.00.3-0.20.1-0.10.1-0.3-0.10.2-0.20.0-0.5
Condit. Reinf. lever presses1.72.33.41.6-1.51.61.6-1.61.61.51.61.6-1.81.5-1.61.5-1.4-1.51.4-1.41.50.4
Condit. Reinf. lever reinforcers received1.82.62.81.6-1.61.71.6-1.61.71.61.61.6-1.71.7-1.71.7-1.6-1.71.7-1.71.60.9
Conditioned reinforcement - actives1.73.03.71.8-1.91.81.9-1.61.81.91.81.8-1.81.8-1.81.8-1.7-1.71.7-1.71.60.5
Conditioned reinforcement - inactives0.91.42.41.1-1.11.21.6-1.01.21.21.21.3-1.41.2-1.21.2-1.2-1.21.1-1.11.10.2
Conditioned locomotion0.81.01.50.9-0.91.01.1-0.81.11.01.21.0-0.91.1-1.11.1-0.8-1.11.1-1.11.10.7
Patch foraging indifference point 0 sec3.86.98.02.6-2.62.72.7-2.72.72.72.72.5-2.82.7-2.82.8-2.6-2.82.6-2.62.71.5
Patch foraging indifference point AUC0.91.26.0-0.90.5-0.9-1.00.7-0.9-0.6-1.0-1.00.8-1.11.0-1.10.51.2-1.31.3-1.4-2.5
Delay disc. indifference point, 0s delay0.30.40.6-0.70.8-0.6-0.60.8-0.6-0.7-0.5-0.60.6-0.50.5-0.50.60.6-0.70.7-0.6-0.2
Delay disc. indifference point, 16s delay0.80.82.41.1-1.20.90.7-1.30.91.30.30.6-1.30.5-0.40.6-1.4-0.50.4-0.40.1-1.5
Delay disc. indifference point, 2s delay0.20.22.8-0.50.5-0.2-0.40.4-0.2-0.4-0.1-0.40.4-0.10.10.10.3-0.00.0-0.00.11.7
Delay disc. indifference point, 24s delay0.70.85.11.0-1.10.70.6-1.20.61.20.00.5-1.20.10.00.1-1.30.00.0-0.0-0.6-2.3
Delay disc. indifference point, 4s delay0.00.00.30.3-0.20.1-0.0-0.20.10.2-0.00.1-0.1-0.0-0.00.0-0.30.0-0.20.2-0.1-0.6
Delay disc. indifference point, 8s delay0.40.43.60.3-0.50.1-0.2-0.50.10.5-0.4-0.1-0.7-0.30.4-0.4-0.80.5-0.50.5-1.0-1.9
Indifference point function ln k3.35.86.82.4-2.22.42.5-2.22.42.22.42.5-2.42.5-2.42.5-2.1-2.52.6-2.62.52.6
Indifference point function log k3.35.86.82.4-2.22.42.5-2.22.42.22.42.5-2.42.5-2.42.5-2.1-2.52.6-2.62.52.6
Patch foraging total patch changes 0 sec4.58.610.22.9-2.83.03.0-2.93.02.93.02.8-3.13.1-3.23.1-2.8-3.12.9-2.93.01.8
Patch foraging total patch changes 12 sec0.10.11.9-0.0-0.20.0-0.1-0.1-0.00.2-0.0-0.10.1-0.20.1-0.2-0.30.2-0.30.3-0.4-1.4
Patch foraging total patch changes 18 sec0.00.10.6-0.20.00.1-0.00.00.10.00.1-0.2-0.10.2-0.30.2-0.1-0.2-0.20.20.2-0.8
Patch foraging total patch changes 24 sec0.61.11.61.1-1.21.11.1-1.11.11.11.21.0-1.11.1-1.21.1-1.3-1.00.8-0.81.0-0.4
Patch foraging total patch changes 6 sec0.91.31.91.1-1.21.21.2-1.21.21.21.21.2-1.21.2-1.41.2-1.3-1.11.0-1.01.00.0
Patch foraging time to switch 0 sec4.89.811.0-3.13.0-3.1-3.13.1-3.1-3.0-3.2-3.23.1-3.33.3-3.32.93.3-3.23.2-3.3-2.3
Patch foraging water rate 0 sec3.88.19.32.9-2.72.92.8-2.82.92.72.93.0-2.83.0-3.03.0-2.7-3.02.9-2.93.02.0
Patch foraging water rate 12 sec3.98.19.72.7-2.62.82.8-2.72.82.72.82.7-2.93.0-3.03.0-2.6-3.03.1-3.13.02.7
Patch foraging water rate 18 sec5.58.59.63.1-3.03.03.0-3.03.02.92.93.1-2.92.9-2.93.0-3.0-3.02.9-2.92.91.7
Patch foraging water rate 24 sec3.44.88.42.0-1.72.12.0-1.82.11.82.12.1-1.72.4-2.32.4-1.9-2.42.4-2.42.62.9
Patch foraging water rate 6 sec13.119.020.84.5-4.24.54.5-4.44.54.44.44.5-4.34.5-4.64.5-4.1-4.54.4-4.44.52.8
Seeking ratio, delayed vs. immediate footshock0.91.12.6-1.21.0-1.1-1.21.1-1.1-0.9-1.1-1.61.2-0.91.0-0.90.91.0-0.90.9-1.0-0.5
Distance traveled before self-admin0.91.11.81.3-1.31.01.0-1.31.01.41.01.2-0.81.0-1.01.0-1.1-1.01.0-1.01.00.6
Distance traveled after self-admin1.51.82.21.3-1.41.41.2-1.31.41.31.41.3-1.31.5-1.51.5-1.2-1.41.4-1.41.40.9
Extensor digitorum longus weight3.312.916.9-3.83.9-3.7-3.93.8-3.8-3.8-3.4-3.74.1-3.53.4-3.54.03.4-3.53.5-3.1-1.6
Bone: elastic displacement1.82.13.0-1.41.5-1.5-1.41.5-1.5-1.5-1.2-1.11.4-1.41.5-1.41.61.4-1.71.7-1.3-1.1
Bone: elastic work0.60.81.4-0.70.7-0.8-0.70.8-0.8-0.8-0.5-0.50.8-0.90.9-0.91.10.9-1.21.2-0.9-1.1
Bone: endosteal estimation0.30.60.90.8-1.00.80.8-1.00.81.00.50.7-0.80.6-0.60.6-0.9-0.60.5-0.50.4-0.8
Bone: endosteal perimeter0.00.00.30.2-0.20.10.1-0.20.10.2-0.00.0-0.2-0.00.1-0.0-0.20.00.1-0.1-0.1-0.5
Epididymis fat weight1.03.44.21.8-1.61.81.9-1.71.91.81.91.8-1.62.0-2.02.0-1.5-2.01.9-1.92.11.9
Delta time in closed arm before/after self-admin5.14.86.7-1.81.6-2.0-2.11.8-2.0-1.6-2.5-1.91.6-2.62.5-2.41.82.4-2.62.6-2.6-2.6
Delta time in open arm before/after self-admin0.10.10.7-0.20.5-0.4-0.30.2-0.4-0.4-0.2-0.50.4-0.20.2-0.40.40.3-0.20.2-0.3-0.8
Diff in mean of infusions in LGA sessions0.00.00.00.1-0.0-0.0-0.0-0.1-0.0-0.00.2-0.10.00.2-0.20.00.1-0.10.1-0.10.10.2
Delay discount exponential model param0.30.42.2-0.60.8-0.4-0.20.8-0.4-0.90.1-0.20.9-0.0-0.1-0.11.0-0.10.1-0.10.51.5
Extinction: sum of active levers before priming2.62.93.7-1.81.7-1.7-1.61.9-1.7-1.8-1.7-1.51.5-1.81.8-1.71.81.6-1.71.7-1.5-1.4
Active lever presses in extinction session 62.92.93.9-1.91.8-1.8-1.91.8-1.8-1.8-1.7-2.01.7-1.81.7-1.61.81.6-1.61.6-1.5-0.7
Bone: final force0.30.51.00.8-0.90.70.8-0.80.70.80.70.8-0.80.5-0.50.5-0.7-0.50.3-0.30.4-1.0
Bone: final moment0.50.81.21.1-1.10.91.0-1.00.91.00.91.1-1.00.8-0.80.8-0.9-0.80.6-0.60.6-0.8
Food consumed during 24 hour testing period1.11.52.51.2-1.11.21.2-1.11.21.01.31.3-1.11.3-1.41.3-1.1-1.31.2-1.21.41.6
Glucose0.10.21.2-0.50.6-0.4-0.20.5-0.4-0.6-0.3-0.40.4-0.00.1-0.00.70.0-0.10.10.21.1
Heart weight0.61.01.41.1-1.11.01.1-1.01.01.21.00.9-1.11.0-1.01.0-1.0-0.90.7-0.70.8-1.1
Delay discount hyperbolic model param0.20.30.9-0.60.7-0.5-0.20.8-0.5-0.8-0.1-0.30.8-0.20.1-0.30.90.1-0.10.10.20.8
Intermittent access intake day 1-15 change0.10.32.0-0.10.20.20.30.30.2-0.30.50.3-0.00.5-0.50.50.3-0.60.4-0.40.81.4
Intermittent access intake escalation0.20.41.80.2-0.10.40.6-0.10.50.10.70.4-0.40.7-0.70.7-0.1-0.80.6-0.61.01.3
Intermittent access intake escalation 20.10.20.6-0.60.6-0.4-0.20.8-0.4-0.6-0.1-0.40.4-0.10.1-0.10.70.1-0.20.20.10.5
Intermitt. access day 1 inactive lever presses0.31.22.2-1.21.3-1.2-0.91.3-1.1-1.5-1.2-1.01.1-1.11.1-1.11.21.1-1.11.1-1.0-0.5
Intermitt. access day 15 inactive lever presses0.51.11.3-1.10.9-1.0-1.01.1-1.0-1.0-1.1-1.01.0-1.11.1-1.11.21.1-1.01.0-1.1-0.7
Intermitt. access escalation Index0.20.31.10.7-0.40.50.5-0.60.50.30.51.0-0.50.5-0.50.5-0.3-0.50.5-0.50.51.1
Intermittent access day 1 total infusions1.01.52.21.4-1.31.31.5-1.31.31.31.21.4-1.31.2-1.21.2-1.1-1.21.2-1.21.10.2
Intermittent access day 15 total infusions2.33.54.41.8-1.71.92.1-1.71.91.62.02.1-1.82.0-2.02.0-1.4-2.01.9-1.92.01.4
Intermittent access terminal intake (last 3 days)1.31.72.41.3-1.21.41.6-1.21.41.21.41.4-1.31.4-1.41.4-1.1-1.41.3-1.31.30.6
Intermittent access total infusions3.23.84.72.0-2.02.12.2-1.92.11.92.02.1-2.02.0-2.02.0-1.9-2.02.0-2.01.90.8
Intermittent access day 1 locomotion2.73.44.21.9-1.51.82.1-1.71.81.61.92.0-1.62.0-2.02.0-1.5-2.01.9-1.92.01.6
Intermittent access day 15 total locomotion2.44.45.71.9-1.72.12.3-1.82.11.82.32.0-1.92.3-2.32.3-1.6-2.32.2-2.22.42.3
Intermittent access total locomotion5.46.47.82.3-2.22.62.7-2.22.62.32.72.5-2.32.7-2.72.7-2.2-2.72.7-2.72.82.3
Intermittent access standard deviation0.00.00.3-0.40.2-0.1-0.30.4-0.1-0.3-0.0-0.50.30.0-0.00.00.2-0.0-0.10.10.00.0
Left kidney weight2.612.313.53.7-3.53.63.6-3.53.63.53.53.6-3.53.6-3.63.6-3.2-3.63.6-3.63.62.0
Right kidney weight2.611.613.03.5-3.43.53.5-3.43.53.53.33.3-3.43.6-3.53.5-2.9-3.63.6-3.63.52.5
Cocaine induced anxiety0.50.71.30.9-1.11.00.7-1.10.91.10.80.8-1.10.8-0.80.8-1.0-0.70.7-0.70.5-0.4
Post-drug Anxiety0.40.50.90.7-0.90.80.4-0.80.70.90.60.5-1.00.6-0.60.6-0.7-0.60.6-0.60.40.1
Baseline Anxiety0.00.00.2-0.20.3-0.2-0.30.3-0.2-0.2-0.1-0.20.2-0.10.1-0.10.30.1-0.10.1-0.00.4
Tail length9.737.941.86.5-6.46.36.4-6.36.36.26.46.4-6.26.3-6.46.3-6.2-6.36.1-6.16.13.0
Length with tail14.061.067.88.2-8.28.18.1-8.18.18.18.08.0-8.17.9-7.97.8-7.9-7.97.7-7.77.53.9
Length without tail9.731.334.95.8-5.75.85.8-5.95.85.95.75.5-5.95.6-5.55.6-5.6-5.65.6-5.65.33.3
Times rat made contact with spout0.40.50.7-0.70.6-0.7-0.70.7-0.7-0.7-0.7-0.60.5-0.80.5-0.80.90.7-0.80.8-0.7-0.4
Lifetime Intake2.53.03.91.8-1.81.92.0-1.71.91.81.82.0-1.81.7-1.71.7-1.8-1.71.7-1.71.60.5
Liver weight, left7.111.715.93.2-2.93.33.4-2.93.32.93.53.6-3.03.6-3.63.6-2.8-3.73.6-3.64.04.0
Liver weight, right0.40.73.90.6-0.30.50.7-0.40.60.30.70.8-0.60.7-0.70.7-0.2-0.91.0-1.01.12.0
Locomotor activity0.20.31.50.5-0.60.50.5-0.70.50.70.20.3-0.70.3-0.30.3-0.4-0.30.2-0.20.1-1.2
Locomotor testing distance0.40.83.5-0.70.6-0.7-0.60.7-0.7-0.5-0.8-0.60.4-0.90.8-1.00.80.9-1.11.1-1.0-1.9
Locomotor testing rearing0.20.41.3-0.50.5-0.5-0.50.6-0.5-0.4-0.5-0.40.3-0.60.5-0.70.70.6-0.70.7-0.5-1.1
Locomotion in novel chamber0.91.21.5-1.00.9-1.1-1.21.1-1.1-0.9-1.1-0.90.9-1.11.1-1.21.21.2-1.11.1-1.2-1.2
Locomotion in novel chamber post-restriction0.10.10.4-0.10.1-0.3-0.4-0.0-0.3-0.1-0.4-0.40.1-0.50.6-0.40.10.5-0.30.3-0.6-0.5
Fecal boli incidents, locomotor time 11.62.33.1-1.31.4-1.5-1.21.4-1.5-1.4-1.8-1.21.4-1.71.7-1.61.61.6-1.71.7-1.6-1.6
Change in fecal boli incidents, locomotor task0.10.12.30.0-0.0-0.0-0.2-0.1-0.0-0.00.2-0.20.40.2-0.20.00.1-0.10.3-0.30.21.5
Time >=10cm from walls, locomotor time 11.81.93.1-1.41.5-1.5-1.31.4-1.5-1.5-1.3-1.41.6-1.31.3-1.31.81.3-1.31.3-1.2-0.3
Bouts of movement, locomotor time 10.70.83.2-0.80.6-0.7-0.80.7-0.7-0.6-0.9-1.00.4-0.80.8-0.70.60.9-0.90.9-1.0-1.8
Total resting periods, locomotor time 10.40.43.9-0.40.2-0.4-0.40.3-0.4-0.2-0.7-0.6-0.0-0.60.6-0.50.20.6-0.60.6-0.8-2.0
Rest time, locomotor task time 11.11.43.2-1.10.8-1.1-1.10.9-1.1-0.8-1.4-1.30.8-1.21.2-1.21.21.3-1.31.3-1.4-1.8
Distance moved, locomotor task time 11.72.58.91.2-1.11.41.3-1.11.41.01.81.3-1.01.7-1.71.6-1.2-1.71.7-1.71.93.0
Vertical activity count, locomotor time 10.71.68.20.8-0.81.10.7-0.81.10.81.30.8-0.51.3-1.31.3-0.9-1.41.5-1.51.52.9
Time >=10cm from walls, locomotor time 20.81.21.7-0.91.0-1.1-1.00.9-1.1-1.0-1.2-0.91.2-1.31.3-1.21.21.3-1.11.1-1.3-0.6
Bouts of movement, locomotor time 20.10.11.00.3-0.50.3-0.0-0.50.20.5-0.2-0.1-0.30.1-0.10.1-0.50.00.0-0.0-0.3-1.0
Total resting periods, locomotor time 20.10.21.8-0.3-0.0-0.2-0.5-0.0-0.20.1-0.6-0.60.1-0.30.3-0.30.00.4-0.40.4-0.6-1.3
Rest time, locomotor task time 23.24.15.5-2.21.9-2.1-1.92.2-2.1-2.0-2.2-2.11.8-2.02.0-2.12.42.0-2.02.0-1.9-1.6
Distance moved, locomotor task time 21.72.05.61.2-1.11.41.1-1.21.41.01.51.1-1.01.5-1.51.5-1.3-1.51.5-1.51.52.4
Vertical activity count, locomotor time 20.60.97.30.4-0.10.60.4-0.30.60.10.90.50.10.9-0.91.0-0.3-1.01.0-1.01.22.7
Light reinforcement 11.84.45.92.2-2.02.12.3-2.22.12.12.22.1-2.22.3-2.42.3-1.9-2.22.0-2.02.20.9
Light reinforcement 20.10.10.5-0.30.4-0.4-0.10.4-0.3-0.4-0.3-0.10.1-0.20.3-0.30.70.3-0.50.5-0.2-0.4
Bone: marrow area0.20.50.90.8-1.00.80.8-0.90.81.00.60.7-0.80.6-0.50.6-0.9-0.60.5-0.50.4-0.8
Bone: maximum diameter0.20.40.6-0.70.7-0.6-0.60.6-0.6-0.7-0.7-0.70.7-0.60.6-0.60.70.5-0.40.4-0.50.3
Bone: maximum force0.10.22.10.5-0.50.30.5-0.40.30.50.40.4-0.40.1-0.20.1-0.3-0.1-0.10.1-0.0-1.5
Bone: maximum moment0.20.41.40.8-0.80.60.8-0.70.60.70.70.7-0.70.4-0.50.4-0.6-0.40.2-0.20.3-1.2
Mean time between licks in bursts0.00.10.3-0.30.4-0.3-0.30.4-0.3-0.4-0.3-0.30.3-0.30.3-0.30.10.3-0.10.1-0.30.5
Mean num. licks in bursts1.52.32.71.6-1.61.51.6-1.51.51.51.51.6-1.41.5-1.51.5-1.4-1.51.5-1.51.51.6
Cd content in liver2.52.83.31.6-1.41.61.8-1.41.61.41.81.8-1.71.7-1.71.8-1.4-1.71.8-1.81.81.7
Co content in liver0.00.00.10.00.1-0.2-0.00.1-0.2-0.10.00.20.2-0.30.3-0.20.10.3-0.20.2-0.3-0.3
Cu content in liver0.20.20.80.3-0.10.30.5-0.10.30.10.50.6-0.40.4-0.40.4-0.2-0.40.5-0.50.60.9
Fe content in liver1.11.41.61.2-1.21.21.2-1.21.21.21.21.2-1.11.2-1.21.2-1.2-1.21.2-1.21.10.4
K content in liver0.70.71.61.0-1.20.80.6-1.20.81.20.60.6-0.70.5-0.50.6-1.2-0.40.4-0.40.1-1.2
Mg content in liver0.40.43.2-0.0-0.2-0.2-0.5-0.1-0.30.2-0.6-0.40.2-0.60.6-0.6-0.10.7-0.60.6-1.0-1.8
Mn content in liver0.60.71.10.8-0.70.80.8-0.70.80.70.80.8-0.70.9-0.91.0-0.7-0.90.9-0.90.91.0
Na content in liver0.10.10.7-0.20.1-0.3-0.20.2-0.3-0.2-0.5-0.30.2-0.40.4-0.30.10.4-0.30.3-0.5-0.9
Rb content in liver1.72.02.61.4-1.21.41.6-1.31.41.31.41.4-1.51.4-1.41.4-1.3-1.41.5-1.51.41.6
Se content in liver0.60.71.3-1.00.9-0.9-1.10.9-0.9-1.0-0.9-1.01.1-0.80.8-0.70.90.8-0.60.6-0.70.5
Sr content in liver2.92.53.3-1.41.4-1.6-1.51.4-1.6-1.4-1.5-1.51.5-1.81.8-1.81.41.8-1.71.7-1.8-1.8
Zn content in liver0.10.10.20.3-0.40.30.3-0.40.30.40.30.1-0.40.2-0.20.2-0.5-0.20.2-0.20.0-0.2
Bone: minimum diameter2.34.35.22.2-2.12.22.3-2.12.22.12.22.2-2.22.1-2.12.1-2.0-2.12.0-2.02.00.9
Time in familiar zone, hab. session 14.24.04.72.1-2.02.12.0-2.12.12.12.12.0-2.02.1-2.02.1-2.2-2.12.0-2.02.01.0
Time in novel zone, hab. session 15.85.86.8-2.52.5-2.5-2.52.6-2.5-2.6-2.5-2.42.4-2.42.3-2.42.62.4-2.42.4-2.3-1.2
Total zone transitions, hab. session 10.00.00.30.0-0.2-0.0-0.2-0.1-0.00.1-0.2-0.10.2-0.10.1-0.1-0.20.2-0.10.1-0.3-0.5
Total locomotion distance, hab. session 10.10.11.50.2-0.40.1-0.2-0.40.00.5-0.3-0.20.0-0.20.2-0.2-0.40.2-0.10.1-0.5-1.2
Locomotion velocity, hab. session 10.10.10.70.1-0.30.1-0.1-0.30.00.4-0.2-0.20.1-0.10.2-0.1-0.30.2-0.00.0-0.4-0.9
Time in familiar zone, hab. session 21.61.72.41.3-1.31.41.3-1.51.31.51.31.2-1.21.3-1.21.3-1.5-1.21.3-1.31.10.8
Time in novel zone, hab. session 21.92.02.8-1.51.5-1.5-1.41.6-1.5-1.6-1.4-1.21.3-1.41.3-1.41.71.3-1.41.4-1.2-0.6
Total zone transitions, hab. session 20.00.10.20.2-0.40.20.0-0.20.20.20.00.2-0.20.2-0.30.2-0.2-0.20.3-0.30.10.1
Total locomotion distance, hab. session 20.20.32.0-0.2-0.1-0.3-0.40.0-0.3-0.0-0.6-0.40.4-0.50.5-0.50.10.6-0.40.4-0.8-1.4
Locomotion velocity, hab. session 20.10.11.10.2-0.40.1-0.1-0.30.10.3-0.2-0.10.0-0.20.1-0.2-0.20.2-0.00.0-0.4-1.1
Novel to familiar place preference ratio1.92.12.8-1.51.5-1.5-1.41.6-1.5-1.6-1.4-1.31.2-1.51.5-1.51.71.4-1.41.4-1.3-1.0
Novelty place preference1.41.52.3-1.21.4-1.3-1.11.4-1.3-1.4-1.2-1.01.0-1.21.2-1.21.51.2-1.21.2-1.0-0.7
Time in novel zone, NPP test1.51.62.5-1.31.4-1.3-1.21.5-1.3-1.5-1.2-1.11.1-1.31.3-1.31.61.2-1.11.1-1.0-0.5
Total zone transitions, NPP test1.11.62.21.4-1.51.31.1-1.51.31.51.21.2-1.31.3-1.31.3-1.4-1.21.2-1.21.10.4
Total locomotion distance, NPP test0.10.11.00.3-0.50.30.1-0.50.20.50.10.1-0.30.1-0.10.1-0.4-0.00.0-0.0-0.1-1.0
Locomotion velocity, NPP test0.40.61.10.9-1.00.80.7-1.00.81.00.70.7-0.90.7-0.70.7-0.9-0.60.6-0.60.5-0.6
Intraocular pressure2.63.86.8-2.22.6-2.1-1.72.6-2.1-2.5-1.7-1.82.4-1.61.7-1.62.31.6-1.71.7-1.10.7
Delta distance traveled before/after self-admin0.80.91.20.7-0.71.00.9-0.81.00.71.00.8-1.11.1-1.11.1-0.9-1.01.0-1.01.00.6
Delta ambulatory time before/after self-admin0.60.71.20.8-0.81.00.8-0.91.00.70.90.7-1.10.9-0.90.9-0.9-0.90.8-0.80.70.3
Parametrial fat weight0.00.10.20.1-0.30.20.2-0.10.20.2-0.00.1-0.40.2-0.30.1-0.4-0.20.4-0.40.10.3
Pavlov. Cond. lever latency0.10.11.3-0.10.00.0-0.10.10.0-0.1-0.0-0.1-0.00.1-0.10.10.1-0.10.3-0.30.21.1
Pavlov. Cond. magazine entry latency1.11.52.91.5-1.61.31.1-1.71.31.71.11.1-1.20.9-0.90.9-1.7-0.90.9-0.90.5-0.8
Pavlov. Cond. change in total contacts2.83.04.42.0-1.91.81.9-1.91.81.91.92.0-1.71.6-1.71.6-2.1-1.61.3-1.31.4-0.7
Pavlov. Cond. index score0.40.51.00.9-0.90.70.7-1.00.71.00.70.7-0.60.5-0.50.5-1.0-0.40.3-0.30.2-1.0
Pavlov. Cond. latency score0.10.21.10.5-0.50.40.4-0.60.40.60.30.4-0.30.1-0.10.1-0.6-0.10.0-0.0-0.1-1.0
Pavlov. Cond. lever contacts0.40.51.00.8-0.80.70.8-0.80.70.80.70.8-0.70.5-0.60.5-0.9-0.50.3-0.30.4-1.0
Pavlov. Cond. magazine entry number2.02.54.8-1.92.0-1.7-1.52.1-1.7-2.1-1.5-1.61.6-1.31.2-1.32.21.2-1.11.1-0.80.9
Pavlov. Cond. intertrial magazine entries4.45.37.2-2.62.7-2.4-2.42.6-2.4-2.7-2.4-2.42.4-2.22.2-2.22.62.1-2.02.0-1.9-0.1
Pavlov. Cond. lever-magazine prob. diff.0.60.71.31.0-1.10.90.8-1.10.91.10.80.8-0.80.6-0.60.6-1.1-0.60.4-0.40.3-1.1
Pavlov. Cond. response bias1.72.13.91.7-1.81.61.4-1.81.61.91.51.5-1.41.3-1.21.3-2.0-1.21.0-1.00.9-0.9
Pavlov. Cond. lever latency2.23.05.0-1.92.0-1.9-1.82.0-1.9-1.9-1.6-1.82.2-1.71.7-1.71.91.6-1.51.5-1.40.2
Pavlov. Cond. magazine entry latency0.60.81.51.0-1.21.00.7-1.21.01.20.80.6-1.10.8-0.80.8-1.2-0.70.7-0.70.4-0.1
Pavlov. Cond. change in total contacts4.06.58.32.7-2.92.72.5-2.82.72.82.62.5-2.92.5-2.52.5-2.7-2.52.5-2.52.30.6
Pavlov. Cond. index score2.02.74.11.8-2.01.81.6-1.91.81.91.51.5-2.01.6-1.61.6-1.9-1.51.5-1.51.2-0.0
Pavlov. Cond. latency score2.02.64.21.8-2.01.71.5-1.91.71.91.51.5-2.01.5-1.51.5-1.9-1.51.4-1.41.20.0
Pavlov. Cond. lever contacts1.72.34.01.7-1.71.61.6-1.71.61.61.41.6-2.01.5-1.51.5-1.6-1.51.3-1.31.3-0.1
Pavlov. Cond. magazine entry number1.31.63.0-1.51.7-1.4-1.01.7-1.4-1.6-1.1-1.01.5-1.21.1-1.21.71.1-1.11.1-0.70.2
Pavlov. Cond. intertrial magazine entries0.20.43.50.10.00.20.50.00.3-0.00.30.5-0.20.5-0.40.50.2-0.50.7-0.70.81.9
Pavlov. Cond. lever-magazine prob. diff.2.12.84.21.8-2.01.81.6-2.01.81.91.51.5-2.11.6-1.61.6-1.9-1.51.5-1.51.20.1
Pavlov. Cond. response bias1.31.72.61.4-1.61.41.3-1.51.41.51.21.1-1.61.3-1.31.3-1.5-1.21.1-1.11.0-0.2
Time in closed arm before self-admin0.30.40.70.6-0.60.60.4-0.80.60.70.70.3-0.50.7-0.60.7-0.6-0.60.7-0.70.60.2
Time in closed arm after self-admin0.20.21.0-0.20.2-0.3-0.60.2-0.4-0.1-0.5-0.60.4-0.60.6-0.40.10.5-0.60.6-0.6-1.0
Time in open arm before self-admin0.10.10.30.2-0.30.20.5-0.00.30.20.10.6-0.30.1-0.20.1-0.3-0.10.0-0.00.10.1
Time in open arm after self-admin0.40.40.8-0.70.9-0.7-0.50.8-0.7-0.9-0.5-0.50.6-0.50.5-0.80.80.6-0.50.5-0.5-0.4
Bone: periosteal estimation0.20.50.70.7-0.80.80.8-0.70.80.70.70.7-0.70.8-0.70.8-0.7-0.80.6-0.60.70.1
Bone: periosteal perimeter0.10.20.30.4-0.40.40.5-0.40.40.40.40.4-0.50.3-0.30.3-0.4-0.40.4-0.40.3-0.1
Bone: post-yield work0.20.30.40.5-0.50.50.5-0.50.50.60.50.3-0.40.5-0.60.5-0.6-0.60.5-0.50.5-0.3
Progressive ratio test 1 active lever presses2.22.74.01.7-1.61.71.8-1.51.71.61.72.0-1.61.7-1.71.7-1.6-1.71.7-1.71.70.7
Progressive ratio test 1 breakpoint2.53.14.41.8-1.71.81.9-1.61.81.71.82.1-1.71.8-1.81.8-1.7-1.81.8-1.81.80.8
Progressive ratio test 1 inactive lever presses1.01.41.91.3-1.21.21.4-1.21.21.21.21.4-1.11.2-1.21.2-1.2-1.21.2-1.21.10.3
Progressive ratio test 2 active lever presses2.12.43.21.7-1.81.71.8-1.61.71.81.51.7-1.71.5-1.51.5-1.6-1.51.4-1.41.3-0.2
Progressive ratio test 2 breakpoint2.22.53.51.7-1.81.71.8-1.61.71.91.61.7-1.81.5-1.51.5-1.7-1.51.4-1.41.3-0.3
Progressive ratio test 2 inactive lever presses0.71.21.91.0-1.01.11.4-0.81.11.01.11.2-1.01.1-1.11.1-0.7-1.11.1-1.11.10.6
Incentive Sensitization - Responses2.33.24.82.0-2.01.91.9-2.01.92.21.71.7-2.11.7-1.71.7-1.9-1.71.7-1.71.50.1
Incentive Sensitization - Breakpoint2.02.64.01.8-1.81.71.7-1.81.72.01.61.6-1.91.5-1.51.5-1.7-1.51.5-1.51.30.0
Sum of active levers in priming session hrs 5-61.61.42.4-1.51.2-1.3-1.31.3-1.3-1.2-1.2-1.61.4-1.21.2-1.01.31.1-1.01.0-0.9-0.1
Progressive ratio0.10.10.30.3-0.30.30.5-0.30.30.30.20.5-0.40.1-0.20.1-0.2-0.20.4-0.40.20.2
Food seeking constrained by brief footshock2.43.04.01.8-2.01.81.7-2.01.82.01.61.5-1.71.8-1.81.6-1.9-1.71.7-1.71.51.2
Seeking ratio, punishment vs. effort0.60.91.20.9-1.01.00.8-1.01.01.00.90.5-0.81.1-1.11.1-1.1-1.00.9-0.91.00.7
Retroperitoneal fat weight0.10.41.60.5-0.50.50.5-0.40.60.50.40.6-0.60.7-0.70.6-0.4-0.70.9-0.90.81.3
Reaction time number correct6.512.514.63.6-3.63.63.5-3.63.63.33.83.5-3.23.6-3.53.7-3.4-3.63.7-3.73.62.9
Reaction time mean minus median0.00.00.1-0.10.0-0.00.10.0-0.00.0-0.1-0.3-0.0-0.10.2-0.2-0.00.10.1-0.1-0.20.2
Reaction time mean minus median AUC0.10.21.00.3-0.30.40.5-0.30.40.40.40.2-0.30.4-0.30.3-0.4-0.40.6-0.60.41.0
Reaction time num false alarms0.30.40.7-0.60.6-0.6-0.50.7-0.6-0.7-0.8-0.60.4-0.70.6-0.60.80.6-0.60.6-0.5-0.1
Reaction time num false alarms AUC0.50.81.5-1.01.0-0.9-0.81.1-0.9-1.0-1.0-0.90.8-1.00.9-0.91.20.8-0.90.9-0.6-0.1
Reaction time trials correct on left6.512.514.63.6-3.63.63.5-3.63.63.33.83.5-3.23.6-3.53.7-3.4-3.63.7-3.73.62.9
Reaction time trials on left6.812.714.83.6-3.63.63.5-3.63.63.43.83.5-3.23.7-3.63.7-3.4-3.73.8-3.83.63.0
Reaction time mean1.72.83.4-1.61.7-1.7-1.51.7-1.7-1.6-1.6-1.71.6-1.71.7-1.81.81.7-1.71.7-1.7-1.2
Reaction time mean AUC1.62.52.9-1.51.5-1.6-1.41.5-1.6-1.4-1.6-1.61.5-1.71.6-1.71.71.7-1.71.7-1.7-1.2
Median of all reaction times2.94.25.1-2.02.1-2.1-1.92.1-2.1-1.9-2.0-2.01.9-2.12.0-2.12.32.1-2.22.2-2.1-1.6
Reaction time omissions0.60.96.40.6-0.50.70.7-0.40.70.50.80.6-0.70.9-0.80.9-0.4-1.01.1-1.11.12.5
Reaction time false alarm rate4.96.88.2-2.82.8-2.7-2.52.8-2.6-2.6-2.9-2.62.4-2.72.6-2.72.82.5-2.72.7-2.4-1.5
Reaction time premature initiation rate3.24.55.92.3-2.42.22.2-2.32.22.42.22.1-2.42.0-2.11.9-2.3-2.02.1-2.11.70.2
Reaction time premature initiations8.114.417.04.0-4.13.93.9-4.03.94.04.13.9-3.93.8-3.83.7-3.9-3.73.9-3.93.51.8
Std. dev. reaction times0.20.40.6-0.70.6-0.6-0.50.6-0.6-0.6-0.5-0.80.7-0.60.6-0.70.60.6-0.60.6-0.5-0.1
Reaction time trials completed6.812.714.83.6-3.63.63.5-3.63.63.43.83.5-3.23.7-3.63.7-3.4-3.73.8-3.83.63.0
Reaction time trials AUC6.111.713.73.5-3.53.53.4-3.43.43.23.73.4-3.13.5-3.43.6-3.2-3.53.6-3.63.52.8
Run reversals in cocaine runway, females0.50.51.0-0.90.5-0.7-1.00.6-0.7-0.6-0.8-1.00.5-0.60.6-0.80.80.7-0.60.6-0.7-0.4
Run reversals in cocaine runway, males0.30.32.1-0.0-0.2-0.2-0.3-0.1-0.20.2-0.7-0.30.1-0.50.6-0.5-0.30.6-0.50.5-0.9-1.4
Latency to leave start box in cocaine runway2.52.83.7-1.61.5-1.7-1.91.5-1.7-1.4-1.9-1.71.5-1.71.7-1.71.61.7-1.81.8-1.8-1.7
Latency to leave start box in cocaine runway, F0.20.20.5-0.30.3-0.5-0.70.1-0.5-0.0-0.6-0.70.3-0.60.5-0.50.50.6-0.50.5-0.7-0.4
Latency to leave start box in cocaine runway, M3.02.83.3-1.71.7-1.6-1.81.7-1.6-1.8-1.8-1.51.7-1.61.6-1.61.51.6-1.81.8-1.6-1.7
Std. dev. time between licks in bursts0.71.01.4-1.11.0-1.0-1.21.0-1.0-1.1-1.0-1.11.0-1.11.1-1.10.81.0-0.80.8-1.1-0.1
Total sessions with >9 infusions0.91.11.91.2-0.91.01.2-1.11.01.01.01.4-0.91.0-1.01.0-1.0-1.01.0-1.01.00.6
Short access day 1 total inactive lever presses1.21.62.11.1-1.21.31.4-1.01.31.21.31.4-1.41.3-1.31.3-1.2-1.31.3-1.31.31.2
Short access day 10 total inactive lever presses0.10.30.6-0.50.6-0.6-0.60.3-0.6-0.4-0.6-0.80.3-0.60.6-0.60.50.6-0.60.6-0.6-0.5
Short access day 1 total infusions0.50.61.21.0-0.80.81.1-0.90.80.90.71.0-0.80.7-0.70.7-0.7-0.70.8-0.80.60.2
Short access day 10 total infusions1.41.82.41.4-1.41.41.5-1.41.41.41.41.5-1.41.3-1.31.3-1.4-1.31.3-1.31.20.3
Short access total infusions1.21.52.31.3-1.31.31.4-1.21.31.31.21.5-1.31.2-1.21.2-1.3-1.21.3-1.31.10.5
Short access day 1 locomotion0.20.20.90.4-0.20.40.7-0.30.40.40.50.6-0.20.5-0.50.5-0.1-0.50.5-0.50.60.9
Short access day 10 total locomotion0.40.71.5-1.01.2-0.9-0.71.1-0.9-1.1-0.7-0.81.0-0.60.6-0.61.10.7-0.70.7-0.50.4
Short access total locomotion0.50.62.30.6-0.30.70.8-0.50.70.40.80.8-0.40.8-0.80.8-0.4-0.80.9-0.91.01.5
One hour access (0.3 mA shock)2.12.43.61.5-1.51.61.9-1.21.61.51.61.7-1.51.7-1.71.7-1.3-1.61.5-1.51.70.5
Compulsive drug intake1.72.02.7-1.31.3-1.5-1.61.2-1.5-1.2-1.6-1.71.3-1.51.5-1.51.31.5-1.41.4-1.5-1.2
One hour access (shock baseline)3.24.96.92.1-2.22.32.6-1.92.32.12.42.6-2.22.3-2.32.3-1.8-2.32.2-2.22.31.3
Social response proportion0.00.00.1-0.10.2-0.2-0.20.2-0.2-0.2-0.3-0.00.2-0.10.1-0.30.10.2-0.20.2-0.2-0.0
Social responses0.81.02.31.2-1.41.10.7-1.41.11.30.60.9-1.00.8-0.90.7-1.5-0.80.8-0.80.5-0.3
Social time0.10.10.7-0.00.4-0.00.30.30.0-0.30.10.20.10.2-0.20.20.2-0.20.2-0.20.30.8
Soleus weight0.10.41.0-0.71.0-0.6-0.30.8-0.6-0.9-0.2-0.50.7-0.40.4-0.41.00.4-0.50.5-0.10.7
Bone: stiffness0.10.21.20.5-0.60.40.6-0.50.40.60.30.4-0.60.2-0.20.2-0.6-0.20.1-0.10.0-1.1
Tibialis anterior weight2.48.210.8-3.13.0-2.9-3.32.8-2.9-2.9-2.9-3.33.1-2.72.8-2.73.02.7-2.92.9-2.6-1.4
Time to tail flick, vehicle, before self-admin2.12.22.91.4-1.31.41.6-1.21.51.41.71.7-1.41.5-1.61.6-1.3-1.61.5-1.51.70.7
Time to tail flick, vehicle, after self-admin0.10.11.20.3-0.50.10.1-0.30.10.4-0.20.40.0-0.20.30.0-0.60.1-0.20.2-0.2-1.1
Time to tail flick, test, before self-admin0.10.10.3-0.30.5-0.3-0.20.4-0.3-0.5-0.3-0.10.3-0.20.2-0.20.50.2-0.30.3-0.10.2
Time to tail flick, test, after self-admin0.80.92.6-0.91.2-1.0-1.21.1-1.0-1.1-0.8-0.91.6-0.70.7-0.41.20.5-0.70.7-0.10.9
Delta time to tail flick, vehicle, before/after SA1.21.21.9-0.80.6-1.0-1.10.6-1.0-0.7-1.4-0.81.1-1.21.3-1.20.61.2-1.31.3-1.3-1.3
Delta time to tail flick, test, before/after SA0.00.00.1-0.0-0.10.1-0.3-0.10.00.1-0.0-0.20.2-0.00.00.2-0.1-0.20.1-0.10.20.4
Tibia length6.919.122.34.5-4.34.44.7-4.34.44.24.64.7-4.44.6-4.74.6-4.0-4.54.3-4.34.62.6
Ambulatory time before self-admin0.20.30.40.6-0.70.50.4-0.50.40.60.60.6-0.30.5-0.60.5-0.4-0.50.6-0.60.60.5
Ambulatory time after self-admin0.91.11.51.1-1.21.10.9-1.21.11.21.10.9-1.11.1-1.11.1-1.0-1.01.0-1.00.90.6
Bone: tissue strength0.70.71.3-0.70.9-0.9-0.61.0-0.9-0.9-0.5-0.40.9-0.80.8-0.81.10.8-0.90.9-0.6-0.6
Total heroin consumption1.11.32.1-1.31.3-1.2-1.31.1-1.2-1.3-0.9-1.41.4-1.00.9-1.21.31.0-1.01.0-0.90.2
Bone: trabecular number0.00.00.2-0.1-0.1-0.0-0.1-0.0-0.00.0-0.1-0.20.3-0.10.1-0.10.10.1-0.20.2-0.1-0.5
Bone: trabecular spacing0.10.21.8-0.30.5-0.1-0.10.4-0.1-0.40.2-0.10.20.2-0.30.30.3-0.30.3-0.30.51.4
Bone: trabecular thickness1.01.22.5-0.80.8-1.0-0.80.9-1.0-0.9-1.1-0.81.0-1.21.2-1.21.21.2-1.31.3-1.2-1.6
Bone: trabecular tissue density2.43.64.3-2.02.0-2.0-2.02.0-2.0-2.0-2.1-1.81.8-1.91.8-1.92.11.9-1.91.9-1.8-0.7
Water consumed over 24 hours0.40.60.9-0.80.7-0.7-0.70.8-0.7-0.7-0.7-0.70.6-0.80.7-0.80.90.7-0.90.9-0.7-0.8
Number of responses in last shaping day0.50.50.9-0.50.8-0.8-0.60.7-0.8-0.8-0.7-0.71.0-0.80.8-0.80.70.8-0.80.8-0.7-0.2