Hub : Genes

Erbin

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Erbin 0.07 0.05 3.8e-07 0.07 0.07 0.07 0.07 3.7e-07 3.9e-07 3.7e-07 5.5e-07
2 Brain intron excision ratio chr2_34932643_34941394 0.04 0.03 5.5e-04 0.03 0.03 0.02 0.02 2.1e-03 1.8e-03 3.0e-03 2.9e-03
3 NAcc gene expression Erbin 0.04 0.03 5.5e-05 0.02 0.03 0.02 0.02 6.7e-04 1.4e-04 1.5e-03 1.4e-03
4 NAcc mRNA stability Erbin 0.02 0.02 9.2e-04 0.02 0.01 0.01 0.01 3.5e-03 1.0e-02 6.3e-03 7.4e-03
5 Liver gene expression Erbin 0.26 0.14 0.0e+00 0.19 0.2 0.19 0.2 4.4e-21 2.0e-21 5.2e-21 2.0e-21
6 OFC gene expression Erbin 0.14 0.11 5.1e-03 0.07 -0 0.03 0.01 9.0e-03 3.6e-01 8.3e-02 2.2e-01
7 Brain gene expression Erbin 0.13 0.14 6.3e-04 0.03 0.03 0.01 0.03 4.3e-04 7.5e-04 5.9e-02 8.7e-04
8 pVTA intron excision ratio chr2_34932643_34935564 0.11 0.18 5.2e-03 0.07 0.05 0.07 0.07 3.8e-04 4.6e-03 6.9e-04 7.6e-04
9 Adipose mRNA stability Erbin 0.03 0.02 2.9e-03 0.01 0 0 0 5.3e-02 1.3e-01 7.6e-02 1.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.71.21.50.9-1.1-1.11.11.11.01.2-1.21.2
Area under the delay curve0.20.21.1-1.00.60.3-0.3-0.1-0.1-0.00.2-0.1
BMI with tail2.16.97.82.6-2.5-2.62.82.72.72.7-2.52.7
BMI without tail0.40.91.40.8-0.8-0.90.91.01.11.1-0.81.2
Body weight1.66.57.8-2.82.72.6-2.6-2.5-2.5-2.42.5-2.4
Weight adjusted by age0.20.20.4-0.50.40.5-0.7-0.5-0.5-0.40.5-0.3
Bone surface0.10.10.30.1-0.3-0.30.30.40.30.5-0.50.5
Bone volume0.20.30.60.3-0.5-0.50.60.60.50.6-0.70.8
Breakpoint value in progressive ratio session3.43.84.61.7-1.8-1.91.82.02.02.0-2.12.0
Number of licking bursts3.64.35.71.8-2.0-2.01.92.02.02.4-2.02.3
Context. condit. distance diff. score1.01.22.3-1.51.31.2-1.1-1.0-1.0-0.81.0-0.7
Locomotion velocity, session 10.40.40.5-0.50.60.6-0.7-0.6-0.6-0.70.6-0.7
Locomotion distance, session 10.50.71.1-1.10.90.8-0.9-0.7-0.7-0.70.8-0.7
Locomotion velocity, session 24.14.85.2-2.02.22.2-2.1-2.2-2.3-2.32.3-2.1
Locomotion distance, session 20.40.50.8-0.90.80.8-0.8-0.6-0.6-0.60.6-0.6
Locomotion velocity, session 34.04.65.5-2.32.32.2-2.3-2.1-2.1-2.02.1-1.9
Locomotion distance, session 36.06.58.1-2.82.82.7-2.6-2.5-2.5-2.32.5-2.0
Stereotopy head waving bouts, day 30.50.61.0-0.70.60.7-1.0-0.8-0.8-0.70.7-0.8
Stereotopy head waving duration, day 30.00.00.10.1-0.00.1-0.4-0.2-0.1-0.00.2-0.1
Locomotion velocity, session 70.10.10.2-0.20.40.4-0.3-0.4-0.4-0.50.5-0.4
Locomotion distance, session 70.30.40.5-0.70.70.7-0.5-0.6-0.6-0.70.7-0.5
Stereotopy head waving bouts, day 70.00.00.10.2-0.1-0.0-0.2-0.1-0.00.20.10.3
Stereotopy head waving duration, day 70.10.10.3-0.10.30.4-0.5-0.5-0.4-0.10.6-0.1
Locomotion velocity, session 82.53.03.3-1.71.71.8-1.8-1.8-1.7-1.71.8-1.5
Locomotion distance, session 82.74.06.1-2.52.32.1-2.1-1.9-1.8-1.71.9-1.6
Degree of sensitization distance2.22.23.41.9-1.7-1.61.61.41.41.2-1.41.1
Degree of sensitization stereotypy0.10.10.30.3-0.2-0.10.10.00.10.50.00.6
Conditioned locomotion0.10.10.20.2-0.2-0.30.30.30.20.4-0.30.4
Cocaine response after cond. corrected1.31.51.8-1.31.31.3-1.2-1.2-1.2-1.11.3-1.1
Cocaine response after cond. not corrected1.61.82.5-1.61.51.4-1.3-1.3-1.3-1.11.4-1.2
Cocaine response before conditioning0.20.20.4-0.70.60.5-0.4-0.4-0.5-0.30.4-0.4
Saline control response0.81.11.5-1.21.11.1-1.0-1.0-1.1-0.91.0-0.9
Bone: connectivity density0.10.10.20.2-0.3-0.30.30.30.20.4-0.40.4
Bone: cortical apparent density0.20.30.5-0.40.40.5-0.4-0.6-0.6-0.50.6-0.7
Bone: cortical area0.20.30.5-0.30.40.5-0.5-0.6-0.7-0.70.5-0.7
Bone: cortical porosity0.80.92.01.4-1.2-1.00.90.80.80.7-0.80.6
Bone: cortical porosity0.91.01.81.4-1.2-1.10.90.90.90.8-0.90.6
Bone: cortical thickness0.40.61.0-0.40.50.7-0.7-0.9-0.9-0.80.8-1.0
Bone: cortical thickness0.80.91.4-0.91.00.9-0.8-0.9-0.9-1.01.0-1.2
Bone: cortical tissue density0.30.30.5-0.40.50.6-0.4-0.6-0.7-0.50.6-0.7
Condit. Reinf. active minus inactive responses0.91.01.41.1-1.2-1.01.00.80.81.0-0.91.1
Condit. Reinf. active-inactive response ratio1.01.11.61.1-1.2-1.10.90.90.91.0-1.01.2
Condit. Reinf. active responses0.10.10.20.3-0.4-0.30.30.20.20.3-0.20.4
Condit. Reinf. inactive responses1.01.21.5-1.21.21.1-1.0-1.0-1.0-1.11.0-1.2
Incentive salience index mean0.81.01.41.0-1.1-1.00.90.80.81.1-0.91.2
Condit. Reinf. lever presses0.40.60.90.6-0.7-0.70.70.70.70.9-0.70.9
Condit. Reinf. active minus inactive responses3.24.04.5-2.12.12.1-1.9-2.0-2.0-1.92.0-1.9
Condit. Reinf. active-inactive response ratio2.42.53.0-1.51.51.6-1.7-1.7-1.7-1.41.7-1.5
Condit. Reinf. active responses1.01.41.9-1.41.21.2-1.2-1.2-1.2-1.11.2-1.1
Condit. Reinf. inactive responses0.00.00.2-0.40.20.2-0.1-0.1-0.1-0.30.1-0.0
Condit. Reinf. lever presses1.52.03.1-1.81.51.4-1.4-1.4-1.4-1.31.3-1.2
Condit. Reinf. lever reinforcers received1.52.12.7-1.61.51.5-1.4-1.5-1.4-1.41.4-1.3
Conditioned reinforcement - actives2.72.73.0-1.71.71.6-1.7-1.6-1.7-1.61.6-1.5
Conditioned reinforcement - inactives0.40.50.6-0.60.60.7-0.8-0.8-0.8-0.70.7-0.7
Conditioned locomotion0.70.81.1-0.70.90.9-1.0-0.9-0.9-0.91.0-0.8
Patch foraging indifference point 0 sec4.77.69.1-3.02.82.8-2.7-2.8-2.7-2.72.7-2.7
Patch foraging indifference point AUC1.61.82.51.5-1.1-1.21.31.31.41.4-1.21.6
Delay disc. indifference point, 0s delay0.10.10.20.4-0.4-0.40.30.40.50.4-0.10.3
Delay disc. indifference point, 16s delay0.40.41.6-1.30.80.6-0.4-0.4-0.5-0.30.4-0.2
Delay disc. indifference point, 2s delay0.10.10.20.2-0.10.00.3-0.1-0.1-0.30.3-0.5
Delay disc. indifference point, 24s delay0.30.31.6-1.30.60.3-0.3-0.0-0.1-0.10.1-0.0
Delay disc. indifference point, 4s delay0.00.00.1-0.20.20.1-0.2-0.0-0.00.10.20.0
Delay disc. indifference point, 8s delay0.20.20.4-0.70.1-0.20.00.50.50.5-0.40.3
Indifference point function ln k5.06.98.3-2.92.62.6-2.7-2.6-2.6-2.62.5-2.6
Indifference point function log k5.06.98.3-2.92.62.6-2.7-2.6-2.6-2.62.5-2.6
Patch foraging total patch changes 0 sec5.89.410.6-3.33.13.1-3.0-3.1-3.0-3.03.0-3.0
Patch foraging total patch changes 12 sec0.00.10.10.3-0.1-0.10.20.30.40.3-0.20.3
Patch foraging total patch changes 18 sec0.00.00.1-0.10.10.1-0.1-0.1-0.10.10.10.2
Patch foraging total patch changes 24 sec0.60.80.9-0.91.00.9-0.8-0.9-0.8-0.80.9-0.8
Patch foraging total patch changes 6 sec0.81.21.4-1.21.21.2-1.2-1.1-0.9-1.01.2-1.0
Patch foraging time to switch 0 sec6.29.610.32.9-3.1-3.23.13.23.23.1-3.12.8
Patch foraging water rate 0 sec5.58.89.4-2.93.03.0-3.1-3.1-3.0-2.93.1-2.7
Patch foraging water rate 12 sec5.78.79.6-2.92.92.9-2.9-3.0-3.0-3.12.9-3.0
Patch foraging water rate 18 sec6.18.28.5-2.82.92.9-2.8-2.9-2.9-2.92.9-2.8
Patch foraging water rate 24 sec3.44.75.6-1.82.12.2-1.9-2.3-2.4-2.32.3-2.1
Patch foraging water rate 6 sec13.720.020.6-4.44.54.5-4.4-4.5-4.5-4.44.5-4.4
Seeking ratio, delayed vs. immediate footshock1.41.62.91.2-1.2-1.21.71.21.21.1-1.11.2
Distance traveled before self-admin1.92.02.4-1.51.51.4-1.6-1.4-1.4-1.41.3-1.4
Distance traveled after self-admin1.31.51.8-1.31.31.2-1.0-1.2-1.2-1.21.2-1.2
Extensor digitorum longus weight3.614.117.44.2-3.9-3.73.93.63.63.7-3.63.7
Bone: elastic displacement1.41.61.91.1-1.3-1.31.31.21.21.4-1.21.4
Bone: elastic work0.71.01.10.7-1.0-1.00.91.11.11.0-1.01.0
Bone: endosteal estimation0.10.30.9-0.90.60.5-0.4-0.4-0.5-0.40.3-0.2
Bone: endosteal perimeter0.00.10.20.0-0.2-0.30.40.40.30.1-0.40.4
Epididymis fat weight0.00.00.0-0.0-0.00.10.1-0.2-0.2-0.10.2-0.1
Delta time in closed arm before/after self-admin5.25.05.91.7-2.1-2.22.32.42.42.4-2.42.2
Delta time in open arm before/after self-admin0.00.00.10.1-0.1-0.1-0.30.10.10.0-0.10.4
Diff in mean of infusions in LGA sessions0.20.30.30.6-0.6-0.50.50.50.50.5-0.50.3
Delay discount exponential model param0.20.21.11.0-0.6-0.40.30.10.20.1-0.30.2
Extinction: sum of active levers before priming2.12.12.61.1-1.4-1.51.21.51.51.6-1.61.6
Active lever presses in extinction session 62.52.42.81.4-1.5-1.61.71.61.51.6-1.61.5
Bone: final force0.50.81.2-1.11.00.9-0.9-0.8-0.8-0.70.8-0.9
Bone: final moment0.71.11.7-1.31.11.1-1.1-1.0-1.0-0.91.0-1.0
Food consumed during 24 hour testing period1.11.31.6-1.11.11.1-1.0-1.2-1.2-1.11.2-1.3
Glucose0.30.41.31.1-0.9-0.70.50.50.50.3-0.60.3
Heart weight0.40.50.80.9-0.7-0.70.70.70.60.7-0.70.7
Delay discount hyperbolic model param0.20.20.70.9-0.5-0.40.30.20.20.1-0.30.3
Intermittent access intake day 1-15 change0.20.20.3-0.20.30.4-0.6-0.5-0.6-0.40.6-0.5
Intermittent access intake escalation0.40.40.6-0.40.40.6-0.8-0.8-0.8-0.70.8-0.7
Intermittent access intake escalation 20.00.00.00.1-0.00.0-0.1-0.2-0.2-0.10.20.0
Intermitt. access day 1 inactive lever presses2.32.42.71.6-1.6-1.61.61.51.51.5-1.61.5
Intermitt. access day 15 inactive lever presses2.93.13.71.7-1.8-1.81.71.81.81.7-1.91.7
Intermitt. access escalation Index0.10.10.2-0.50.30.3-0.4-0.3-0.3-0.40.2-0.5
Intermittent access day 1 total infusions0.91.01.6-1.01.01.0-1.3-1.0-1.0-1.00.9-0.9
Intermittent access day 15 total infusions2.32.63.6-1.41.51.6-1.9-1.7-1.7-1.61.6-1.6
Intermittent access terminal intake (last 3 days)1.01.11.5-1.01.01.0-1.2-1.1-1.0-1.01.0-0.9
Intermittent access total infusions2.42.73.7-1.61.61.6-1.9-1.7-1.6-1.61.6-1.6
Intermittent access day 1 locomotion2.72.93.4-1.51.61.7-1.8-1.8-1.7-1.71.7-1.6
Intermittent access day 15 total locomotion2.93.13.7-1.31.61.7-1.9-1.9-1.9-1.91.8-1.9
Intermittent access total locomotion5.76.57.3-2.22.42.5-2.7-2.7-2.6-2.62.5-2.6
Intermittent access standard deviation0.50.50.80.9-0.7-0.60.70.60.60.8-0.50.8
Left kidney weight1.02.73.0-1.71.71.7-1.6-1.7-1.7-1.61.7-1.6
Right kidney weight0.20.71.0-0.80.90.8-0.7-0.8-0.8-0.80.8-1.0
Cocaine induced anxiety0.40.51.1-1.00.90.7-0.6-0.5-0.5-0.60.5-0.5
Post-drug Anxiety0.80.91.5-1.21.11.0-0.7-0.8-0.8-1.00.8-1.1
Baseline Anxiety0.00.00.2-0.20.10.1-0.0-0.2-0.2-0.20.1-0.4
Tail length8.425.528.0-5.15.15.1-5.3-5.0-5.0-5.05.1-4.8
Length with tail12.345.147.5-6.86.76.7-6.9-6.7-6.7-6.76.5-6.7
Length without tail7.316.017.1-4.04.04.0-3.9-4.0-4.1-4.03.8-4.1
Times rat made contact with spout0.30.40.50.6-0.7-0.70.60.70.60.5-0.60.6
Lifetime Intake2.12.43.4-1.51.51.5-1.8-1.6-1.5-1.51.5-1.4
Liver weight, left1.32.13.2-0.71.01.3-1.3-1.6-1.6-1.81.6-1.7
Liver weight, right0.00.10.10.3-0.3-0.30.30.30.30.1-0.30.0
Locomotor activity0.10.20.6-0.80.60.5-0.2-0.4-0.4-0.10.4-0.1
Locomotor testing distance0.60.91.60.4-0.8-0.91.01.00.91.3-1.01.1
Locomotor testing rearing0.40.61.10.3-0.7-0.70.80.80.81.0-0.81.0
Locomotion in novel chamber1.31.62.21.0-1.2-1.30.81.31.41.3-1.51.4
Locomotion in novel chamber post-restriction0.20.20.40.2-0.3-0.40.50.60.60.3-0.60.3
Fecal boli incidents, locomotor time 12.62.93.31.3-1.7-1.81.71.81.81.7-1.71.8
Change in fecal boli incidents, locomotor task0.10.10.20.40.00.1-0.3-0.2-0.2-0.30.0-0.4
Time >=10cm from walls, locomotor time 11.31.31.61.0-1.3-1.21.21.21.11.1-1.21.2
Bouts of movement, locomotor time 10.60.71.10.5-0.7-0.80.90.90.90.9-0.71.0
Total resting periods, locomotor time 10.30.40.70.2-0.4-0.60.60.70.70.7-0.50.8
Rest time, locomotor task time 12.22.42.81.3-1.5-1.61.51.61.61.6-1.51.7
Distance moved, locomotor task time 12.73.04.3-1.21.61.7-1.4-1.9-1.9-1.91.6-2.1
Vertical activity count, locomotor time 12.22.33.3-0.91.41.5-1.1-1.6-1.7-1.71.6-1.8
Time >=10cm from walls, locomotor time 20.80.81.30.7-0.9-1.00.61.11.10.8-1.10.8
Bouts of movement, locomotor time 20.00.00.2-0.40.30.2-0.1-0.00.0-0.10.1-0.0
Total resting periods, locomotor time 20.10.10.20.0-0.2-0.30.50.40.40.4-0.30.5
Rest time, locomotor task time 23.74.35.11.8-2.2-2.12.12.02.02.1-2.02.3
Distance moved, locomotor task time 22.32.63.7-1.21.61.7-1.5-1.6-1.6-1.71.5-1.9
Vertical activity count, locomotor time 21.11.21.9-0.30.91.1-0.9-1.2-1.1-1.21.4-1.4
Light reinforcement 12.64.85.5-2.22.12.2-2.0-2.2-2.2-2.22.3-2.2
Light reinforcement 20.10.10.10.3-0.4-0.40.30.30.30.3-0.20.3
Bone: marrow area0.10.20.8-0.90.60.5-0.4-0.3-0.4-0.40.3-0.1
Bone: maximum diameter0.40.71.20.9-0.9-0.91.10.90.80.4-0.90.6
Bone: maximum force0.10.10.3-0.50.40.3-0.4-0.2-0.2-0.10.2-0.1
Bone: maximum moment0.20.30.7-0.80.60.5-0.6-0.5-0.5-0.40.4-0.3
Mean time between licks in bursts0.00.10.10.3-0.3-0.30.20.30.20.2-0.30.1
Mean num. licks in bursts2.42.94.2-1.51.61.6-1.6-1.6-1.6-2.01.7-1.9
Cd content in liver0.50.50.6-0.40.70.7-0.8-0.7-0.7-0.80.7-0.8
Co content in liver0.10.10.3-0.60.30.2-0.2-0.1-0.1-0.20.0-0.2
Cu content in liver0.50.60.8-0.60.60.6-0.9-0.8-0.7-0.80.7-0.9
Fe content in liver1.82.22.5-1.31.41.5-1.5-1.6-1.6-1.51.6-1.5
K content in liver1.51.52.2-1.31.51.3-1.3-1.1-1.1-1.11.1-1.1
Mg content in liver0.10.10.2-0.30.50.3-0.2-0.0-0.1-0.10.1-0.0
Mn content in liver0.40.50.5-0.60.60.7-0.7-0.7-0.7-0.70.7-0.7
Na content in liver0.20.20.3-0.60.50.4-0.4-0.4-0.4-0.30.4-0.3
Rb content in liver1.01.21.6-1.21.01.0-1.3-1.0-1.0-1.21.0-1.2
Se content in liver0.10.10.20.5-0.4-0.30.20.30.30.2-0.30.2
Sr content in liver3.43.13.61.5-1.6-1.71.61.91.91.8-1.91.8
Zn content in liver0.00.00.0-0.0-0.0-0.10.20.20.20.2-0.20.2
Bone: minimum diameter1.93.53.9-1.91.91.9-1.9-1.8-1.9-2.01.8-1.8
Time in familiar zone, hab. session 14.44.14.5-2.02.12.1-1.9-2.1-2.1-2.02.1-1.9
Time in novel zone, hab. session 16.15.96.42.4-2.5-2.52.42.42.42.5-2.52.4
Total zone transitions, hab. session 10.00.00.0-0.00.10.1-0.10.00.10.1-0.00.1
Total locomotion distance, hab. session 10.00.00.1-0.20.1-0.00.10.20.20.3-0.20.2
Locomotion velocity, hab. session 10.00.00.0-0.20.1-0.00.10.20.20.1-0.10.1
Time in familiar zone, hab. session 21.31.41.6-1.21.21.2-1.2-1.2-1.0-1.21.3-1.1
Time in novel zone, hab. session 21.71.71.91.4-1.4-1.41.31.31.21.3-1.41.3
Total zone transitions, hab. session 20.10.10.2-0.30.40.4-0.4-0.3-0.3-0.40.4-0.4
Total locomotion distance, hab. session 20.10.20.30.2-0.2-0.40.40.50.50.5-0.40.5
Locomotion velocity, hab. session 20.00.00.0-0.10.10.00.00.10.10.1-0.00.1
Novel to familiar place preference ratio2.12.22.61.3-1.5-1.51.61.51.41.6-1.41.5
Novelty place preference1.51.51.81.1-1.3-1.21.31.21.11.3-1.21.2
Time in novel zone, NPP test1.61.61.91.2-1.3-1.31.41.21.21.4-1.21.2
Total zone transitions, NPP test1.41.92.1-1.41.51.4-1.4-1.4-1.3-1.31.4-1.4
Total locomotion distance, NPP test0.00.00.1-0.30.30.2-0.2-0.1-0.10.10.1-0.1
Locomotion velocity, NPP test0.40.50.7-0.90.90.8-0.8-0.7-0.7-0.50.7-0.7
Intraocular pressure2.53.44.81.9-2.2-2.01.81.71.61.8-1.71.9
Delta distance traveled before/after self-admin0.30.40.5-0.70.60.6-0.3-0.6-0.6-0.60.7-0.6
Delta ambulatory time before/after self-admin0.30.40.6-0.80.70.6-0.4-0.6-0.5-0.60.7-0.6
Parametrial fat weight0.00.00.10.1-0.00.0-0.2-0.1-0.2-0.20.1-0.2
Pavlov. Cond. lever latency0.00.00.10.3-0.2-0.1-0.00.00.00.00.0-0.0
Pavlov. Cond. magazine entry latency1.41.82.7-1.61.61.4-1.0-1.2-1.1-1.41.2-1.3
Pavlov. Cond. change in total contacts2.62.73.5-1.91.81.7-1.5-1.6-1.6-1.61.6-1.3
Pavlov. Cond. index score0.30.30.7-0.80.70.6-0.3-0.5-0.4-0.60.4-0.5
Pavlov. Cond. latency score0.10.10.2-0.50.40.3-0.0-0.1-0.1-0.30.1-0.2
Pavlov. Cond. lever contacts0.20.30.5-0.70.70.6-0.4-0.5-0.5-0.50.4-0.4
Pavlov. Cond. magazine entry number1.21.52.71.6-1.5-1.30.91.01.01.1-1.01.1
Pavlov. Cond. intertrial magazine entries3.94.85.92.3-2.4-2.32.12.12.12.1-2.12.1
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-1.00.90.8-0.5-0.6-0.6-0.70.6-0.6
Pavlov. Cond. response bias1.41.72.5-1.61.61.4-1.1-1.2-1.2-1.31.2-1.2
Pavlov. Cond. lever latency1.41.93.11.8-1.5-1.41.31.31.41.1-1.31.1
Pavlov. Cond. magazine entry latency0.50.61.2-1.10.90.8-0.7-0.6-0.7-0.50.6-0.8
Pavlov. Cond. change in total contacts4.25.87.8-2.82.62.5-2.4-2.4-2.4-2.22.3-2.2
Pavlov. Cond. index score1.82.33.9-2.01.71.6-1.4-1.4-1.5-1.31.4-1.4
Pavlov. Cond. latency score1.92.33.9-2.01.71.6-1.4-1.4-1.5-1.31.4-1.5
Pavlov. Cond. lever contacts1.62.13.3-1.81.61.5-1.4-1.4-1.5-1.31.4-1.3
Pavlov. Cond. magazine entry number1.11.32.31.5-1.4-1.21.01.01.10.8-1.01.1
Pavlov. Cond. intertrial magazine entries0.20.30.7-0.20.30.4-0.4-0.6-0.6-0.80.6-0.8
Pavlov. Cond. lever-magazine prob. diff.2.02.54.1-2.01.71.6-1.5-1.5-1.5-1.31.4-1.5
Pavlov. Cond. response bias1.21.72.6-1.61.41.3-1.2-1.2-1.3-1.11.2-1.2
Time in closed arm before self-admin0.00.10.1-0.20.20.2-0.0-0.2-0.2-0.40.3-0.2
Time in closed arm after self-admin0.70.71.20.8-0.7-0.81.10.80.90.9-0.90.9
Time in open arm before self-admin0.00.00.1-0.20.30.2-0.3-0.2-0.20.00.1-0.2
Time in open arm after self-admin0.20.30.40.6-0.6-0.50.20.50.50.5-0.50.6
Bone: periosteal estimation0.10.30.5-0.70.60.5-0.5-0.5-0.6-0.60.5-0.4
Bone: periosteal perimeter0.00.00.1-0.40.20.1-0.0-0.0-0.1-0.2-0.1-0.1
Bone: post-yield work0.00.00.00.00.00.1-0.2-0.1-0.1-0.00.10.1
Progressive ratio test 1 active lever presses1.01.11.6-1.21.01.0-1.2-1.1-1.0-1.00.9-0.8
Progressive ratio test 1 breakpoint1.11.11.6-1.31.11.1-1.2-1.0-1.0-1.00.9-0.8
Progressive ratio test 1 inactive lever presses0.60.60.9-1.00.80.8-0.9-0.8-0.8-0.80.7-0.7
Progressive ratio test 2 active lever presses0.40.40.6-0.70.50.6-0.8-0.7-0.7-0.60.6-0.4
Progressive ratio test 2 breakpoint0.30.30.5-0.60.50.5-0.7-0.6-0.6-0.50.5-0.3
Progressive ratio test 2 inactive lever presses0.40.40.7-0.60.50.6-0.8-0.7-0.7-0.70.6-0.6
Incentive Sensitization - Responses0.70.70.8-0.90.80.8-0.9-0.8-0.9-0.90.8-0.7
Incentive Sensitization - Breakpoint0.50.50.6-0.70.60.6-0.7-0.7-0.8-0.70.7-0.6
Sum of active levers in priming session hrs 5-60.90.91.41.2-0.9-0.91.10.80.80.9-0.90.9
Progressive ratio0.00.00.00.2-0.1-0.1-0.20.1-0.00.1-0.20.0
Food seeking constrained by brief footshock2.12.63.5-1.91.71.7-1.3-1.6-1.7-1.51.5-1.6
Seeking ratio, punishment vs. effort0.70.91.1-1.10.90.9-0.5-1.0-1.0-0.91.1-1.0
Retroperitoneal fat weight0.41.31.91.4-1.4-1.21.21.01.00.9-1.00.8
Reaction time number correct8.712.513.0-3.43.63.6-3.4-3.5-3.5-3.63.6-3.6
Reaction time mean minus median0.00.10.1-0.40.20.2-0.2-0.2-0.1-0.30.1-0.2
Reaction time mean minus median AUC0.40.50.6-0.80.70.7-0.7-0.7-0.7-0.80.6-0.8
Reaction time num false alarms0.50.60.80.8-0.8-0.80.90.70.60.9-0.80.8
Reaction time num false alarms AUC0.81.11.41.1-1.1-1.11.11.00.81.2-1.01.1
Reaction time trials correct on left8.712.513.0-3.43.63.6-3.4-3.5-3.5-3.63.6-3.6
Reaction time trials on left9.012.913.3-3.53.63.6-3.5-3.6-3.6-3.63.6-3.6
Reaction time mean1.62.22.61.3-1.5-1.51.41.51.51.6-1.51.6
Reaction time mean AUC1.52.02.31.2-1.4-1.41.31.41.41.5-1.41.5
Median of all reaction times2.73.84.51.8-2.0-1.91.81.92.02.1-1.92.1
Reaction time omissions0.30.50.8-0.50.50.6-0.5-0.8-0.8-0.70.7-0.9
Reaction time false alarm rate5.37.47.92.7-2.8-2.82.82.62.52.8-2.72.8
Reaction time premature initiation rate3.34.46.0-2.42.22.1-1.9-2.0-2.0-2.12.0-1.8
Reaction time premature initiations10.314.516.6-4.13.93.9-3.6-3.7-3.8-3.93.7-3.6
Std. dev. reaction times0.10.10.10.2-0.3-0.30.30.20.20.3-0.30.3
Reaction time trials completed9.012.913.3-3.53.63.6-3.5-3.6-3.6-3.63.6-3.6
Reaction time trials AUC8.111.712.1-3.33.53.5-3.3-3.4-3.4-3.43.5-3.4
Run reversals in cocaine runway, females0.60.61.10.9-0.7-0.71.00.70.50.6-0.80.6
Run reversals in cocaine runway, males0.20.20.3-0.1-0.2-0.30.30.60.50.4-0.50.4
Latency to leave start box in cocaine runway2.52.73.11.8-1.7-1.71.61.71.71.7-1.51.6
Latency to leave start box in cocaine runway, F0.30.30.50.6-0.6-0.60.70.60.60.5-0.40.5
Latency to leave start box in cocaine runway, M3.02.93.31.8-1.6-1.71.51.71.71.8-1.71.8
Std. dev. time between licks in bursts1.11.31.51.1-1.1-1.21.01.21.21.2-1.21.1
Total sessions with >9 infusions0.70.81.2-0.90.90.9-1.1-0.9-0.9-0.80.8-0.7
Short access day 1 total inactive lever presses0.10.10.20.10.20.2-0.5-0.4-0.3-0.30.4-0.5
Short access day 10 total inactive lever presses0.70.81.00.6-0.8-0.80.90.90.90.9-1.00.9
Short access day 1 total infusions1.41.52.0-1.11.21.2-1.4-1.2-1.2-1.31.2-1.2
Short access day 10 total infusions1.31.52.2-1.31.21.2-1.5-1.2-1.2-1.11.1-1.0
Short access total infusions1.92.22.9-1.41.51.5-1.7-1.5-1.5-1.51.4-1.4
Short access day 1 locomotion0.50.50.7-0.40.60.7-0.8-0.8-0.8-0.80.7-0.8
Short access day 10 total locomotion0.00.00.10.20.10.2-0.2-0.3-0.3-0.20.2-0.1
Short access total locomotion2.32.43.0-0.91.41.6-1.7-1.7-1.7-1.61.6-1.6
One hour access (0.3 mA shock)1.31.51.9-1.11.11.2-1.3-1.3-1.3-1.21.4-0.9
Compulsive drug intake0.10.10.40.3-0.4-0.40.60.30.30.2-0.30.3
One hour access (shock baseline)2.12.53.3-1.51.61.6-1.8-1.6-1.6-1.41.7-1.4
Social response proportion0.10.10.20.1-0.2-0.20.40.20.10.2-0.30.1
Social responses0.81.12.0-1.41.21.1-0.7-0.9-1.0-0.90.9-1.0
Social time0.00.00.1-0.1-0.00.00.0-0.1-0.2-0.10.1-0.3
Soleus weight0.10.20.40.7-0.6-0.50.30.30.40.4-0.40.4
Bone: stiffness0.20.30.6-0.80.60.5-0.5-0.4-0.4-0.40.4-0.4
Tibialis anterior weight2.27.59.23.0-2.8-2.72.82.62.62.8-2.62.7
Time to tail flick, vehicle, before self-admin4.64.75.0-2.22.22.2-2.1-2.2-2.2-2.02.2-2.1
Time to tail flick, vehicle, after self-admin1.21.31.8-1.31.31.2-1.3-1.0-1.0-0.91.0-0.9
Time to tail flick, test, before self-admin0.20.20.4-0.30.40.4-0.5-0.5-0.6-0.50.6-0.6
Time to tail flick, test, after self-admin0.20.21.31.1-0.6-0.40.60.10.10.2-0.10.1
Delta time to tail flick, vehicle, before/after SA1.51.51.81.1-1.1-1.11.11.31.31.3-1.31.3
Delta time to tail flick, test, before/after SA0.00.00.10.4-0.2-0.10.30.10.20.0-0.10.1
Tibia length6.819.221.7-4.54.34.3-4.7-4.4-4.4-4.24.5-4.3
Ambulatory time before self-admin0.70.70.8-0.80.90.8-0.9-0.8-0.8-0.90.7-0.9
Ambulatory time after self-admin0.70.81.3-1.10.90.9-0.6-0.8-0.8-0.90.8-1.0
Bone: tissue strength0.90.91.10.9-1.0-1.00.90.90.91.0-1.01.0
Total heroin consumption1.21.42.11.5-1.2-1.21.31.11.01.1-1.20.8
Bone: trabecular number0.00.10.10.0-0.2-0.20.20.30.20.3-0.30.3
Bone: trabecular spacing0.10.10.20.5-0.10.1-0.2-0.4-0.3-0.30.4-0.3
Bone: trabecular thickness1.41.72.10.8-1.2-1.31.41.41.31.4-1.41.4
Bone: trabecular tissue density2.33.33.81.8-1.8-1.81.91.81.71.9-1.71.7
Water consumed over 24 hours0.60.71.00.8-0.9-0.80.90.80.80.9-0.81.0
Number of responses in last shaping day0.30.30.60.7-0.6-0.60.50.50.50.5-0.60.4