Hub : Genes

Erbb3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Erbb3 0.17 0.09 1.1e-16 0.16 0.16 0.15 0.16 3.3e-15 1.4e-14 3.2e-14 9.5e-15
2 pVTA gene expression Erbb3 0.04 0.03 4.2e-03 0.03 0.02 0.01 0.02 3.6e-03 4.4e-03 5.4e-02 8.8e-03
3 BLA gene expression Erbb3 0.12 0.08 3.4e-07 0.15 0.14 0.15 0.14 2.1e-08 5.0e-08 3.4e-08 8.4e-08
4 NAcc alternative TSS NM_017218.3 0.02 0.01 1.3e-03 0.02 0.02 0.02 0.02 3.4e-04 1.2e-03 8.1e-04 4.2e-04
5 NAcc alternative TSS XM_017594700.3 0.02 0.01 9.2e-04 0.02 0.02 0.02 0.02 2.1e-04 1.2e-03 4.0e-04 2.7e-04
6 NAcc alternative TSS NM_017218.3 0.03 0.02 6.6e-05 0.03 0.03 0.03 0.03 1.7e-05 6.1e-05 5.7e-05 4.8e-05
7 NAcc alternative TSS XM_017594700.3 0.02 0.01 9.3e-04 0.03 0.02 0.01 0.02 1.0e-04 1.1e-03 5.7e-03 3.0e-04
8 Liver mRNA stability Erbb3 0.02 0.02 7.0e-03 0.02 0.01 0.02 0.02 1.5e-03 9.5e-03 3.7e-03 3.0e-03
9 NAcc gene expression Erbb3 0.06 0.04 6.8e-09 0.06 0.05 0.06 0.06 3.0e-09 1.1e-08 1.1e-09 2.5e-09
10 PL gene expression Erbb3 0.06 0.04 4.1e-06 0.03 0.06 0.05 0.05 1.6e-04 1.2e-06 4.4e-06 8.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.51.04.3-0.5-0.5-0.7-0.60.6-0.60.6-1.0-1.52.1
Area under the delay curve0.00.00.00.10.1-0.10.0-0.00.0-0.0-0.1-0.00.0
BMI with tail7.225.328.55.35.35.35.2-5.25.2-5.2-5.34.5-3.1
BMI without tail1.16.16.82.62.62.62.6-2.62.6-2.6-2.62.3-1.6
Body weight1.35.66.62.42.42.42.6-2.62.6-2.6-2.02.3-1.9
Weight adjusted by age0.00.00.1-0.1-0.1-0.1-0.10.1-0.10.10.4-0.2-0.2
Bone surface1.83.611.9-1.5-1.5-1.6-1.61.6-1.61.6-0.9-2.63.5
Bone volume1.52.911.0-1.3-1.3-1.3-1.31.3-1.31.3-1.2-2.43.3
Breakpoint value in progressive ratio session0.50.81.2-1.0-1.0-1.0-0.90.9-0.90.91.1-0.50.4
Number of licking bursts1.34.05.02.22.22.12.0-2.02.0-2.0-1.62.1-1.9
Context. condit. distance diff. score0.20.30.40.70.70.60.5-0.50.5-0.5-0.60.4-0.4
Locomotion velocity, session 10.20.31.2-0.3-0.3-0.3-0.20.2-0.20.2-0.5-0.81.1
Locomotion distance, session 10.91.23.0-1.0-1.0-1.0-0.90.9-0.90.9-0.1-1.51.7
Locomotion velocity, session 22.73.25.3-1.6-1.6-1.7-1.81.8-1.81.80.6-2.12.3
Locomotion distance, session 24.36.18.0-2.6-2.6-2.5-2.52.5-2.52.51.5-2.82.5
Locomotion velocity, session 34.24.86.2-2.4-2.4-2.4-2.32.3-2.32.32.5-1.91.1
Locomotion distance, session 30.00.10.2-0.3-0.3-0.2-0.10.1-0.10.10.4-0.2-0.1
Stereotopy head waving bouts, day 35.66.67.7-2.6-2.6-2.8-2.72.7-2.72.72.5-2.41.9
Stereotopy head waving duration, day 33.64.45.3-2.0-2.0-2.2-2.32.3-2.32.31.9-1.91.6
Locomotion velocity, session 70.20.20.3-0.3-0.3-0.4-0.40.4-0.40.40.0-0.60.6
Locomotion distance, session 70.30.30.90.60.60.60.5-0.50.5-0.5-0.10.7-0.9
Stereotopy head waving bouts, day 71.51.72.5-1.3-1.3-1.4-1.21.2-1.21.20.7-1.61.6
Stereotopy head waving duration, day 71.51.93.2-1.4-1.4-1.5-1.31.3-1.31.30.6-1.71.8
Locomotion velocity, session 82.73.24.8-1.8-1.8-1.8-1.81.8-1.81.80.8-2.22.1
Locomotion distance, session 80.60.91.2-0.9-0.9-1.0-1.01.0-1.01.00.6-1.10.8
Degree of sensitization distance0.50.50.80.80.80.80.7-0.70.7-0.7-0.90.6-0.3
Degree of sensitization stereotypy0.10.10.5-0.1-0.1-0.2-0.00.0-0.00.0-0.4-0.50.7
Conditioned locomotion1.82.13.21.51.51.31.5-1.51.5-1.5-0.41.6-1.8
Cocaine response after cond. corrected2.33.54.52.12.11.91.8-1.81.8-1.8-1.12.0-1.9
Cocaine response after cond. not corrected2.84.04.72.12.12.12.0-2.02.0-2.0-1.12.2-2.1
Cocaine response before conditioning0.40.51.0-1.0-1.0-0.7-0.60.6-0.60.60.7-0.50.6
Saline control response0.81.11.40.90.91.01.2-1.21.2-1.2-0.51.2-1.1
Bone: connectivity density0.30.62.3-0.4-0.4-0.5-0.50.5-0.50.5-0.6-1.11.5
Bone: cortical apparent density0.81.32.21.41.41.21.1-1.11.1-1.1-1.51.0-0.5
Bone: cortical area0.30.63.00.50.50.30.4-0.40.4-0.4-1.7-0.31.1
Bone: cortical porosity0.10.10.4-0.1-0.1-0.1-0.30.3-0.30.3-0.4-0.50.7
Bone: cortical porosity0.20.20.9-0.0-0.0-0.0-0.10.1-0.10.1-0.9-0.50.9
Bone: cortical thickness0.91.54.51.21.21.11.2-1.21.2-1.2-2.10.60.3
Bone: cortical thickness1.01.21.41.21.21.11.1-1.11.1-1.1-0.81.2-1.0
Bone: cortical tissue density0.60.91.51.21.21.00.8-0.80.8-0.8-1.20.8-0.4
Condit. Reinf. active minus inactive responses1.92.22.8-1.4-1.4-1.5-1.71.7-1.71.71.4-1.41.0
Condit. Reinf. active-inactive response ratio0.10.10.3-0.2-0.2-0.2-0.40.4-0.40.40.6-0.1-0.2
Condit. Reinf. active responses3.44.45.1-2.0-2.0-2.2-2.32.3-2.32.31.5-2.21.8
Condit. Reinf. inactive responses2.33.04.2-1.8-1.8-1.9-1.71.7-1.71.71.0-2.01.8
Incentive salience index mean1.82.43.1-1.4-1.4-1.6-1.71.7-1.71.70.9-1.81.4
Condit. Reinf. lever presses1.21.73.4-1.1-1.1-1.3-1.31.3-1.31.30.2-1.81.8
Condit. Reinf. active minus inactive responses1.01.64.0-1.4-1.4-1.2-1.31.3-1.31.32.0-0.6-0.0
Condit. Reinf. active-inactive response ratio0.20.41.9-0.3-0.3-0.1-0.20.2-0.20.21.40.5-1.1
Condit. Reinf. active responses1.31.82.5-1.5-1.5-1.4-1.41.4-1.41.41.6-1.10.7
Condit. Reinf. inactive responses0.50.71.0-0.8-0.8-0.9-0.80.8-0.80.80.4-1.01.0
Condit. Reinf. lever presses1.52.24.3-1.6-1.6-1.6-1.51.5-1.51.52.1-0.80.4
Condit. Reinf. lever reinforcers received0.81.12.1-1.1-1.1-1.1-1.11.1-1.11.11.5-0.70.3
Conditioned reinforcement - actives0.00.10.60.70.70.20.1-0.10.1-0.1-0.30.10.1
Conditioned reinforcement - inactives0.41.01.61.31.31.10.9-0.90.9-0.9-0.71.0-0.9
Conditioned locomotion1.52.22.9-1.2-1.2-1.5-1.71.7-1.71.71.1-1.51.6
Patch foraging indifference point 0 sec1.74.78.22.32.32.22.2-2.22.2-2.2-2.91.6-0.7
Patch foraging indifference point AUC0.30.81.3-0.8-0.8-0.9-1.01.0-1.01.01.2-0.60.2
Delay disc. indifference point, 0s delay0.40.52.80.60.60.40.4-0.40.4-0.4-1.7-0.40.8
Delay disc. indifference point, 16s delay0.10.20.3-0.6-0.6-0.4-0.40.4-0.40.40.4-0.40.4
Delay disc. indifference point, 2s delay0.10.10.50.10.10.0-0.10.1-0.10.1-0.7-0.10.4
Delay disc. indifference point, 24s delay0.10.20.30.30.30.50.5-0.50.5-0.5-0.40.4-0.3
Delay disc. indifference point, 4s delay0.70.81.3-0.8-0.8-0.9-0.90.9-0.90.90.2-1.11.1
Delay disc. indifference point, 8s delay0.20.30.70.70.70.30.5-0.50.5-0.5-0.10.5-0.8
Indifference point function ln k0.10.20.20.40.40.30.5-0.50.5-0.5-0.50.4-0.2
Indifference point function log k0.10.20.20.40.40.30.5-0.50.5-0.5-0.50.4-0.2
Patch foraging total patch changes 0 sec1.44.27.22.22.22.12.1-2.12.1-2.1-2.71.6-0.7
Patch foraging total patch changes 12 sec2.02.63.11.81.81.71.7-1.71.7-1.7-1.41.6-1.2
Patch foraging total patch changes 18 sec0.00.00.10.10.10.10.1-0.10.1-0.1-0.20.00.1
Patch foraging total patch changes 24 sec0.10.30.90.50.50.60.6-0.60.6-0.6-0.90.40.1
Patch foraging total patch changes 6 sec1.32.23.71.61.61.61.6-1.61.6-1.6-1.91.0-0.4
Patch foraging time to switch 0 sec0.00.20.60.20.20.30.4-0.40.4-0.4-0.8-0.20.5
Patch foraging water rate 0 sec0.31.31.91.21.21.21.0-1.01.0-1.0-0.61.4-1.3
Patch foraging water rate 12 sec0.51.82.81.41.41.41.3-1.31.3-1.3-0.81.7-1.5
Patch foraging water rate 18 sec0.61.34.60.90.90.90.8-0.80.8-0.80.61.8-2.2
Patch foraging water rate 24 sec3.65.19.42.32.32.22.1-2.12.1-2.1-0.62.9-3.1
Patch foraging water rate 6 sec0.20.31.30.00.00.1-0.00.0-0.00.01.00.8-1.1
Seeking ratio, delayed vs. immediate footshock1.11.62.0-1.2-1.2-1.4-1.41.4-1.41.40.8-0.91.4
Distance traveled before self-admin0.81.71.9-1.4-1.4-1.4-1.41.4-1.41.41.3-1.00.8
Distance traveled after self-admin0.00.00.1-0.2-0.2-0.20.1-0.10.1-0.10.3-0.1-0.0
Extensor digitorum longus weight5.622.325.65.15.15.04.9-4.94.9-4.9-4.24.6-3.7
Bone: elastic displacement0.00.00.00.00.00.10.0-0.00.0-0.0-0.10.10.1
Bone: elastic work0.40.61.70.70.70.70.7-0.70.7-0.7-1.30.40.2
Bone: endosteal estimation0.20.52.00.70.70.60.6-0.60.6-0.6-1.40.20.4
Bone: endosteal perimeter0.61.42.4-1.2-1.2-1.2-1.21.2-1.21.20.2-1.41.5
Epididymis fat weight0.00.21.00.30.30.10.0-0.00.0-0.00.60.7-1.0
Delta time in closed arm before/after self-admin3.83.66.62.02.02.01.7-1.71.7-1.7-0.72.6-2.3
Delta time in open arm before/after self-admin0.60.71.00.70.70.71.0-1.01.0-1.0-0.70.5-0.6
Diff in mean of infusions in LGA sessions0.91.62.4-1.3-1.3-1.3-1.31.3-1.31.31.6-1.00.6
Delay discount exponential model param0.00.00.00.00.00.20.1-0.10.1-0.1-0.00.1-0.0
Extinction: sum of active levers before priming0.50.82.3-0.8-0.8-0.8-1.01.0-1.01.01.5-0.3-0.2
Active lever presses in extinction session 60.40.40.5-0.6-0.6-0.6-0.70.7-0.70.70.3-0.70.5
Bone: final force1.42.37.01.41.41.31.5-1.51.5-1.5-2.60.40.5
Bone: final moment1.42.27.01.41.41.31.5-1.51.5-1.5-2.60.40.5
Food consumed during 24 hour testing period0.20.40.50.60.60.70.6-0.60.6-0.6-0.70.6-0.3
Glucose1.21.92.31.31.31.41.5-1.51.5-1.5-1.41.2-0.9
Heart weight0.10.10.7-0.1-0.1-0.2-0.30.3-0.30.30.80.1-0.4
Delay discount hyperbolic model param0.00.00.1-0.1-0.10.0-0.10.1-0.10.10.40.0-0.1
Intermittent access intake day 1-15 change0.00.20.9-0.1-0.1-0.3-0.40.4-0.40.41.00.3-0.3
Intermittent access intake escalation0.00.20.9-0.1-0.1-0.2-0.30.3-0.30.30.90.3-0.4
Intermittent access intake escalation 20.30.51.5-0.7-0.7-0.7-0.70.7-0.70.71.2-0.20.0
Intermitt. access day 1 inactive lever presses0.00.31.3-0.1-0.10.1-0.10.1-0.10.11.10.5-1.1
Intermitt. access day 15 inactive lever presses0.10.81.2-0.9-0.9-0.8-1.01.0-1.01.01.1-0.70.1
Intermitt. access escalation Index0.10.20.6-0.5-0.5-0.3-0.10.1-0.10.1-0.4-0.50.8
Intermittent access day 1 total infusions0.10.30.40.60.60.70.4-0.40.4-0.4-0.40.5-0.4
Intermittent access day 15 total infusions0.00.00.00.20.20.2-0.00.0-0.00.0-0.20.20.1
Intermittent access terminal intake (last 3 days)0.10.10.4-0.2-0.2-0.3-0.40.4-0.40.4-0.2-0.40.7
Intermittent access total infusions0.10.10.40.50.50.40.2-0.20.2-0.2-0.60.10.1
Intermittent access day 1 locomotion0.20.40.70.60.60.70.6-0.60.6-0.60.10.6-0.8
Intermittent access day 15 total locomotion0.00.10.30.20.2-0.0-0.20.2-0.20.20.50.2-0.2
Intermittent access total locomotion0.00.00.10.30.3-0.0-0.10.1-0.10.10.30.1-0.1
Intermittent access standard deviation0.21.11.2-1.1-1.1-0.9-1.11.1-1.11.10.8-1.01.0
Left kidney weight0.00.10.20.20.20.10.2-0.20.2-0.20.30.3-0.5
Right kidney weight0.00.31.3-0.3-0.3-0.5-0.50.5-0.50.51.1-0.1-0.3
Cocaine induced anxiety1.13.03.5-1.8-1.8-1.8-1.81.8-1.81.80.9-1.61.9
Post-drug Anxiety2.12.44.6-1.6-1.6-1.5-1.61.6-1.61.60.2-1.32.1
Baseline Anxiety0.00.00.0-0.0-0.00.10.1-0.10.1-0.1-0.20.2-0.0
Tail length2.010.514.9-3.5-3.5-3.5-3.33.3-3.33.33.9-2.61.5
Length with tail0.93.97.9-2.2-2.2-2.0-1.91.9-1.91.92.8-1.30.4
Length without tail0.21.21.41.01.01.11.2-1.21.2-1.2-0.61.1-1.0
Times rat made contact with spout1.51.71.91.31.31.41.3-1.31.3-1.3-0.91.3-1.3
Lifetime Intake0.50.61.70.90.90.80.7-0.70.7-0.7-1.30.50.0
Liver weight, left0.40.71.11.11.10.90.8-0.80.8-0.8-0.80.9-0.6
Liver weight, right0.10.10.4-0.3-0.3-0.2-0.20.2-0.20.20.70.1-0.4
Locomotor activity3.55.57.0-2.7-2.7-2.5-2.32.3-2.32.32.0-2.32.0
Locomotor testing distance1.12.73.4-1.8-1.8-1.7-1.61.6-1.61.61.3-1.61.5
Locomotor testing rearing0.00.10.1-0.0-0.00.10.2-0.20.2-0.20.30.2-0.4
Locomotion in novel chamber0.00.10.20.10.10.40.2-0.20.2-0.2-0.20.3-0.0
Locomotion in novel chamber post-restriction1.85.56.8-2.6-2.6-2.5-2.52.5-2.52.52.6-1.61.3
Fecal boli incidents, locomotor time 10.51.31.70.90.91.21.3-1.31.3-1.3-0.51.3-1.3
Change in fecal boli incidents, locomotor task1.41.42.5-1.3-1.3-1.2-1.11.1-1.11.10.3-1.51.6
Time >=10cm from walls, locomotor time 10.20.21.00.20.20.30.3-0.30.3-0.3-1.0-0.40.8
Bouts of movement, locomotor time 10.40.50.8-0.7-0.7-0.8-0.70.7-0.70.70.9-0.70.2
Total resting periods, locomotor time 11.11.31.7-1.2-1.2-1.2-1.21.2-1.21.21.3-1.00.5
Rest time, locomotor task time 10.60.91.3-1.2-1.2-1.0-0.90.9-0.90.90.7-1.10.9
Distance moved, locomotor task time 10.10.41.60.60.60.50.4-0.40.4-0.4-1.3-0.20.7
Vertical activity count, locomotor time 10.21.72.91.71.71.41.2-1.21.2-1.2-1.31.2-0.7
Time >=10cm from walls, locomotor time 20.51.41.71.21.21.21.2-1.21.2-1.2-1.01.3-1.1
Bouts of movement, locomotor time 20.20.61.7-0.8-0.8-0.7-0.60.6-0.60.60.1-1.31.1
Total resting periods, locomotor time 20.20.82.2-0.9-0.9-0.8-0.70.7-0.70.7-0.0-1.51.3
Rest time, locomotor task time 20.30.50.9-0.9-0.9-0.7-0.50.5-0.50.50.0-1.00.9
Distance moved, locomotor task time 20.20.30.60.70.70.50.5-0.50.5-0.50.10.6-0.8
Vertical activity count, locomotor time 21.02.43.11.81.81.81.5-1.51.5-1.5-0.81.8-1.7
Light reinforcement 11.46.47.6-2.8-2.8-2.7-2.62.6-2.62.62.2-2.41.9
Light reinforcement 20.61.31.7-1.3-1.3-1.2-1.11.1-1.11.11.0-1.10.8
Bone: marrow area0.20.41.80.70.70.60.6-0.60.6-0.6-1.30.20.3
Bone: maximum diameter0.91.83.6-1.2-1.2-1.3-1.31.3-1.31.30.1-1.61.9
Bone: maximum force1.32.67.11.61.61.41.7-1.71.7-1.7-2.70.70.3
Bone: maximum moment1.42.67.11.61.61.51.7-1.71.7-1.7-2.70.70.2
Mean time between licks in bursts0.10.81.2-0.7-0.7-1.0-1.11.1-1.11.11.0-0.50.3
Mean num. licks in bursts0.30.71.1-1.0-1.0-0.8-0.80.8-0.80.80.8-0.90.7
Cd content in liver0.30.40.7-0.3-0.3-0.5-0.80.8-0.80.80.3-0.40.4
Co content in liver1.92.24.0-1.5-1.5-1.5-1.61.6-1.61.62.0-1.00.4
Cu content in liver0.20.21.10.20.20.20.1-0.10.1-0.1-1.1-0.41.0
Fe content in liver0.30.40.60.80.80.70.6-0.60.6-0.6-0.40.5-0.6
K content in liver1.11.11.6-1.1-1.1-1.1-1.01.0-1.01.00.6-1.21.3
Mg content in liver1.41.61.8-1.3-1.3-1.3-1.31.3-1.31.31.0-1.31.1
Mn content in liver3.53.97.4-1.9-1.9-2.0-1.91.9-1.91.90.6-2.62.7
Na content in liver0.10.10.3-0.0-0.0-0.20.1-0.10.1-0.1-0.4-0.40.6
Rb content in liver0.20.21.2-0.1-0.10.1-0.10.1-0.10.1-0.9-0.51.1
Se content in liver0.00.00.0-0.0-0.0-0.2-0.20.2-0.20.20.1-0.20.0
Sr content in liver0.10.10.20.10.1-0.1-0.20.2-0.20.20.40.3-0.4
Zn content in liver1.31.55.0-1.2-1.2-1.1-1.21.2-1.21.22.2-0.2-0.7
Bone: minimum diameter0.10.21.20.10.10.0-0.00.0-0.00.0-1.1-0.41.0
Time in familiar zone, hab. session 13.13.46.1-2.1-2.1-1.9-1.91.9-1.91.92.5-1.30.6
Time in novel zone, hab. session 11.71.95.31.51.51.31.3-1.31.3-1.3-2.30.60.3
Total zone transitions, hab. session 11.11.62.8-1.2-1.2-1.3-1.21.2-1.21.20.3-1.61.7
Total locomotion distance, hab. session 13.54.97.6-2.2-2.2-2.2-2.22.2-2.22.20.9-2.72.8
Locomotion velocity, hab. session 13.24.66.4-2.2-2.2-2.2-2.12.1-2.12.11.1-2.52.4
Time in familiar zone, hab. session 22.93.36.8-1.8-1.8-1.8-1.91.9-1.91.92.6-1.00.2
Time in novel zone, hab. session 23.03.27.71.81.81.81.9-1.91.9-1.9-2.80.9-0.0
Total zone transitions, hab. session 20.30.41.90.00.0-0.00.1-0.10.1-0.1-1.3-0.81.4
Total locomotion distance, hab. session 20.91.22.2-1.2-1.2-1.1-1.01.0-1.01.00.3-1.51.4
Locomotion velocity, hab. session 21.21.73.1-1.3-1.3-1.3-1.11.1-1.11.10.3-1.81.8
Novel to familiar place preference ratio1.11.44.41.21.21.11.2-1.21.2-1.2-2.10.40.5
Novelty place preference0.70.93.10.90.90.80.8-0.80.8-0.8-1.80.20.6
Time in novel zone, NPP test1.11.34.01.21.21.11.1-1.11.1-1.1-2.00.40.4
Total zone transitions, NPP test0.10.20.70.10.10.10.3-0.30.3-0.3-0.9-0.40.6
Total locomotion distance, NPP test0.20.31.2-0.4-0.4-0.5-0.30.3-0.30.3-0.5-1.01.1
Locomotion velocity, NPP test0.40.61.4-0.7-0.7-0.8-0.60.6-0.60.6-0.1-1.21.2
Intraocular pressure0.20.31.5-0.1-0.1-0.0-0.10.1-0.10.11.10.7-1.2
Delta distance traveled before/after self-admin0.70.71.00.80.80.81.0-1.01.0-1.0-0.60.8-0.6
Delta ambulatory time before/after self-admin0.30.40.70.60.60.60.8-0.80.8-0.8-0.80.4-0.1
Parametrial fat weight0.20.61.10.70.70.80.8-0.80.8-0.8-1.10.5-0.1
Pavlov. Cond. lever latency0.70.92.10.60.60.90.9-0.90.9-0.90.21.3-1.4
Pavlov. Cond. magazine entry latency1.41.82.5-1.2-1.2-1.4-1.61.6-1.61.61.3-1.20.7
Pavlov. Cond. change in total contacts0.10.10.40.50.50.30.1-0.10.1-0.1-0.60.1-0.0
Pavlov. Cond. index score0.81.11.4-0.8-0.8-1.0-1.21.2-1.21.20.5-1.21.0
Pavlov. Cond. latency score1.11.42.0-1.0-1.0-1.2-1.31.3-1.31.30.4-1.41.4
Pavlov. Cond. lever contacts0.40.51.4-0.3-0.3-0.6-0.70.7-0.70.7-0.4-1.01.2
Pavlov. Cond. magazine entry number0.60.81.10.70.70.91.1-1.11.1-1.1-0.90.7-0.3
Pavlov. Cond. intertrial magazine entries0.10.10.60.10.10.10.2-0.20.2-0.20.40.5-0.8
Pavlov. Cond. lever-magazine prob. diff.0.91.11.5-0.8-0.8-1.1-1.21.2-1.21.20.6-1.21.0
Pavlov. Cond. response bias0.60.71.1-0.6-0.6-0.9-1.01.0-1.01.00.8-0.80.4
Pavlov. Cond. lever latency1.42.02.61.61.61.61.4-1.41.4-1.4-1.51.0-0.8
Pavlov. Cond. magazine entry latency2.02.83.3-1.8-1.8-1.8-1.81.8-1.81.81.6-1.41.0
Pavlov. Cond. change in total contacts0.30.71.1-0.9-0.9-0.9-0.90.9-0.90.91.1-0.60.3
Pavlov. Cond. index score1.42.22.7-1.6-1.6-1.6-1.61.6-1.61.61.6-1.10.8
Pavlov. Cond. latency score1.72.73.4-1.9-1.9-1.8-1.71.7-1.71.71.7-1.31.0
Pavlov. Cond. lever contacts1.11.62.4-1.4-1.4-1.4-1.31.3-1.31.31.5-0.80.5
Pavlov. Cond. magazine entry number2.22.83.31.81.81.81.8-1.81.8-1.8-1.61.4-1.1
Pavlov. Cond. intertrial magazine entries0.92.02.31.41.41.41.5-1.51.5-1.5-1.01.4-1.2
Pavlov. Cond. lever-magazine prob. diff.1.72.63.1-1.7-1.7-1.7-1.71.7-1.71.71.6-1.31.0
Pavlov. Cond. response bias1.72.43.6-1.7-1.7-1.6-1.71.7-1.71.71.9-0.90.6
Time in closed arm before self-admin0.10.10.8-0.2-0.2-0.2-0.10.1-0.10.1-0.5-0.50.9
Time in closed arm after self-admin0.60.71.60.80.80.80.8-0.80.8-0.8-0.81.3-0.5
Time in open arm before self-admin0.00.00.00.10.10.1-0.10.1-0.10.1-0.0-0.1-0.0
Time in open arm after self-admin1.71.82.51.31.31.31.6-1.61.6-1.6-1.00.8-1.2
Bone: periosteal estimation0.30.74.00.60.60.50.5-0.50.5-0.5-2.0-0.21.1
Bone: periosteal perimeter0.40.72.6-0.6-0.6-0.6-0.70.7-0.70.7-0.7-1.21.6
Bone: post-yield work0.30.50.80.90.90.70.8-0.80.8-0.8-0.90.6-0.3
Progressive ratio test 1 active lever presses0.30.60.90.90.90.80.7-0.70.7-0.7-0.80.6-0.5
Progressive ratio test 1 breakpoint0.30.60.90.90.90.90.7-0.70.7-0.7-0.80.7-0.5
Progressive ratio test 1 inactive lever presses0.10.20.3-0.4-0.4-0.3-0.50.5-0.50.50.2-0.30.3
Progressive ratio test 2 active lever presses0.00.00.10.00.0-0.1-0.20.2-0.20.20.0-0.30.2
Progressive ratio test 2 breakpoint0.10.10.2-0.1-0.1-0.2-0.30.3-0.30.30.2-0.40.3
Progressive ratio test 2 inactive lever presses0.00.10.50.40.40.20.0-0.00.0-0.0-0.7-0.20.5
Incentive Sensitization - Responses0.10.30.5-0.5-0.5-0.5-0.50.5-0.50.50.7-0.60.2
Incentive Sensitization - Breakpoint0.20.50.7-0.7-0.7-0.7-0.70.7-0.70.70.8-0.80.4
Sum of active levers in priming session hrs 5-60.10.10.2-0.3-0.3-0.3-0.30.3-0.30.30.40.1-0.0
Progressive ratio0.72.02.51.41.41.51.6-1.61.6-1.6-1.01.1-1.1
Food seeking constrained by brief footshock1.72.13.3-1.6-1.6-1.6-1.51.5-1.51.51.8-1.10.5
Seeking ratio, punishment vs. effort1.53.44.1-1.9-1.9-2.0-2.02.0-2.02.02.0-1.20.9
Retroperitoneal fat weight2.511.112.53.33.33.53.5-3.53.5-3.5-2.53.4-2.9
Reaction time number correct0.62.02.61.41.41.41.4-1.41.4-1.4-0.61.6-1.6
Reaction time mean minus median0.31.82.2-1.5-1.5-1.3-1.41.4-1.41.41.4-1.00.9
Reaction time mean minus median AUC0.53.74.2-2.0-2.0-1.9-2.02.0-2.02.01.1-2.02.1
Reaction time num false alarms0.61.11.51.01.01.01.2-1.21.2-1.2-0.90.7-0.7
Reaction time num false alarms AUC0.61.41.81.11.11.11.3-1.31.3-1.3-0.81.0-1.0
Reaction time trials correct on left0.62.02.61.41.41.41.4-1.41.4-1.4-0.61.6-1.6
Reaction time trials on left0.51.82.31.41.41.41.4-1.41.4-1.4-0.61.5-1.5
Reaction time mean1.22.63.2-1.6-1.6-1.6-1.81.8-1.81.81.0-1.51.6
Reaction time mean AUC0.61.51.8-1.1-1.1-1.2-1.31.3-1.31.30.6-1.11.3
Median of all reaction times1.11.72.2-1.2-1.2-1.3-1.51.5-1.51.50.7-1.31.4
Reaction time omissions0.10.20.7-0.3-0.3-0.4-0.40.4-0.40.4-0.2-0.40.9
Reaction time false alarm rate0.10.20.30.30.30.30.5-0.50.5-0.5-0.60.10.0
Reaction time premature initiation rate0.60.93.4-1.0-1.0-0.9-0.80.8-0.80.81.8-0.5-0.3
Reaction time premature initiations0.10.42.2-0.2-0.2-0.20.0-0.00.0-0.01.50.5-1.2
Std. dev. reaction times0.51.72.0-1.3-1.3-1.3-1.41.4-1.41.40.9-1.21.2
Reaction time trials completed0.51.82.31.41.41.41.4-1.41.4-1.4-0.61.5-1.5
Reaction time trials AUC0.72.33.11.61.61.51.6-1.61.6-1.6-0.61.7-1.8
Run reversals in cocaine runway, females3.53.95.0-2.0-2.0-2.0-2.02.0-2.02.01.6-2.21.7
Run reversals in cocaine runway, males2.93.23.7-1.9-1.9-1.9-1.91.9-1.91.91.2-1.51.7
Latency to leave start box in cocaine runway0.20.31.4-0.3-0.3-0.6-0.30.3-0.30.3-0.6-0.81.2
Latency to leave start box in cocaine runway, F0.50.72.5-0.5-0.5-0.8-0.40.4-0.40.4-0.8-1.21.6
Latency to leave start box in cocaine runway, M0.10.10.20.40.40.30.3-0.30.3-0.30.10.5-0.5
Std. dev. time between licks in bursts0.81.62.5-1.2-1.2-1.2-1.31.3-1.31.30.5-1.31.6
Total sessions with >9 infusions0.50.62.00.70.70.80.7-0.70.7-0.7-1.40.60.2
Short access day 1 total inactive lever presses0.10.10.4-0.3-0.3-0.3-0.30.3-0.30.30.6-0.0-0.2
Short access day 10 total inactive lever presses0.00.31.70.20.20.50.3-0.30.3-0.30.60.8-1.3
Short access day 1 total infusions0.30.61.90.80.80.80.7-0.70.7-0.7-1.40.60.1
Short access day 10 total infusions0.10.20.40.40.40.60.5-0.50.5-0.5-0.60.4-0.2
Short access total infusions0.60.82.50.90.90.90.9-0.90.9-0.9-1.60.50.1
Short access day 1 locomotion0.00.10.1-0.2-0.2-0.2-0.30.3-0.30.30.3-0.00.1
Short access day 10 total locomotion0.20.74.0-0.5-0.5-0.7-0.60.6-0.60.62.0-0.1-0.5
Short access total locomotion0.00.00.2-0.1-0.1-0.1-0.20.2-0.20.20.50.1-0.1
One hour access (0.3 mA shock)0.20.30.60.80.80.50.4-0.40.4-0.4-0.30.5-0.5
Compulsive drug intake0.00.00.1-0.2-0.2-0.3-0.10.1-0.10.10.0-0.20.3
One hour access (shock baseline)0.00.00.10.20.20.1-0.10.1-0.10.10.20.0-0.2
Social response proportion1.11.32.0-1.4-1.4-1.3-1.01.0-1.01.01.2-1.40.9
Social responses9.612.516.1-4.0-4.0-3.8-3.53.5-3.53.53.5-3.52.6
Social time1.11.72.01.21.21.41.4-1.41.4-1.4-0.91.2-1.2
Soleus weight5.416.018.24.24.24.24.2-4.24.2-4.2-4.33.5-2.3
Bone: stiffness2.24.08.42.12.11.92.1-2.12.1-2.1-2.91.1-0.2
Tibialis anterior weight1.24.14.82.22.22.22.1-2.12.1-2.1-2.11.9-1.2
Time to tail flick, vehicle, before self-admin1.41.72.0-1.4-1.4-1.4-1.41.4-1.41.40.8-0.81.4
Time to tail flick, vehicle, after self-admin0.10.31.8-0.3-0.3-0.3-0.10.1-0.10.11.30.2-1.0
Time to tail flick, test, before self-admin1.21.42.4-1.1-1.1-1.1-1.21.2-1.21.20.3-1.41.5
Time to tail flick, test, after self-admin0.00.10.3-0.2-0.2-0.2-0.10.1-0.10.1-0.2-0.20.5
Delta time to tail flick, vehicle, before/after SA1.81.93.81.31.31.31.5-1.51.5-1.5-0.21.2-2.0
Delta time to tail flick, test, before/after SA0.40.51.50.50.50.50.6-0.60.6-0.60.41.0-1.2
Tibia length0.72.03.4-1.5-1.5-1.4-1.51.5-1.51.51.8-1.10.4
Ambulatory time before self-admin0.10.40.5-0.7-0.7-0.7-0.70.7-0.70.70.7-0.50.3
Ambulatory time after self-admin0.00.00.0-0.1-0.1-0.10.1-0.10.1-0.10.1-0.00.0
Bone: tissue strength3.84.07.12.02.02.02.1-2.12.1-2.1-2.71.4-0.6
Total heroin consumption2.52.93.5-1.9-1.9-1.9-1.71.7-1.71.71.6-1.61.3
Bone: trabecular number0.81.63.2-1.1-1.1-1.4-1.21.2-1.21.20.3-1.61.8
Bone: trabecular spacing1.31.95.51.11.11.41.2-1.21.2-1.20.31.9-2.3
Bone: trabecular thickness1.52.18.5-1.0-1.0-1.0-0.90.9-0.90.9-1.3-2.12.9
Bone: trabecular tissue density4.37.58.52.92.92.82.9-2.92.9-2.9-2.52.6-2.0
Water consumed over 24 hours0.20.41.40.50.50.60.6-0.60.6-0.6-1.20.20.3
Number of responses in last shaping day0.70.92.2-0.7-0.7-0.9-1.11.1-1.11.11.5-0.40.3