Hub : Genes

Erbb3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Erbb3 0.17 0.09 1.1e-16 0.16 0.16 0.15 0.16 3.3e-15 1.4e-14 3.2e-14 9.0e-15
2 pVTA gene expression Erbb3 0.04 0.03 4.2e-03 0.03 0.02 0.01 0.02 3.6e-03 4.4e-03 5.4e-02 9.0e-03
3 BLA gene expression Erbb3 0.12 0.08 3.4e-07 0.15 0.14 0.15 0.14 2.1e-08 5.0e-08 3.4e-08 8.4e-08
4 NAcc alternative TSS XM_017594700.3 0.02 0.01 9.2e-04 0.02 0.02 0.02 0.02 2.1e-04 1.2e-03 4.0e-04 2.7e-04
5 NAcc alternative TSS NM_017218.3 0.03 0.02 6.6e-05 0.03 0.03 0.03 0.03 1.7e-05 6.1e-05 5.7e-05 4.7e-05
6 NAcc alternative TSS XM_017594700.3 0.02 0.01 9.3e-04 0.03 0.02 0.02 0.02 1.0e-04 1.1e-03 2.7e-04 3.2e-04
7 NAcc alternative TSS NM_017218.3 0.02 0.01 1.3e-03 0.02 0.02 0.02 0.02 3.4e-04 1.2e-03 8.1e-04 4.2e-04
8 Liver mRNA stability Erbb3 0.02 0.02 7.0e-03 0.02 0.01 0.02 0.02 1.5e-03 9.5e-03 3.7e-03 2.9e-03
9 NAcc gene expression Erbb3 0.06 0.04 6.8e-09 0.06 0.05 0.06 0.06 3.0e-09 1.1e-08 1.1e-09 2.6e-09
10 PL gene expression Erbb3 0.06 0.04 4.1e-06 0.03 0.06 0.05 0.05 1.6e-04 1.2e-06 4.4e-06 8.3e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.61.04.30.50.50.7-0.60.6-0.60.61.01.52.1
Area under the delay curve0.00.00.0-0.1-0.10.10.0-0.00.0-0.00.10.00.0
BMI with tail7.325.328.5-5.3-5.3-5.35.2-5.25.2-5.25.3-4.5-3.1
BMI without tail2.06.16.8-2.6-2.6-2.62.6-2.62.6-2.62.6-2.3-1.6
Body weight1.35.66.6-2.4-2.4-2.42.6-2.62.6-2.62.0-2.3-1.9
Weight adjusted by age0.00.00.10.10.10.1-0.10.1-0.10.1-0.40.2-0.2
Bone surface2.03.611.91.51.51.6-1.61.6-1.61.60.92.63.5
Bone volume1.62.911.01.31.31.3-1.31.3-1.31.31.22.43.3
Breakpoint value in progressive ratio session0.70.81.21.01.01.0-0.90.9-0.90.9-1.10.50.4
Number of licking bursts2.54.05.0-2.2-2.2-2.12.0-2.02.0-2.01.6-2.1-1.9
Context. condit. distance diff. score0.20.30.4-0.7-0.7-0.60.5-0.50.5-0.50.6-0.4-0.4
Locomotion velocity, session 10.20.31.20.30.30.3-0.20.2-0.20.20.50.81.1
Locomotion distance, session 10.91.23.01.01.01.0-0.90.9-0.90.90.11.51.7
Locomotion velocity, session 22.83.25.31.61.61.7-1.81.8-1.81.8-0.62.12.3
Locomotion distance, session 24.46.18.02.62.62.5-2.52.5-2.52.5-1.52.82.5
Locomotion velocity, session 34.24.86.22.42.42.4-2.32.3-2.32.3-2.51.91.1
Locomotion distance, session 30.00.10.20.30.30.2-0.10.1-0.10.1-0.40.2-0.1
Stereotopy head waving bouts, day 35.76.67.72.62.62.8-2.72.7-2.72.7-2.52.41.9
Stereotopy head waving duration, day 33.74.45.32.02.02.2-2.32.3-2.32.3-1.91.91.6
Locomotion velocity, session 70.20.20.30.30.30.4-0.40.4-0.40.4-0.00.60.6
Locomotion distance, session 70.30.30.9-0.6-0.6-0.60.5-0.50.5-0.50.1-0.7-0.9
Stereotopy head waving bouts, day 71.51.72.51.31.31.4-1.21.2-1.21.2-0.71.61.6
Stereotopy head waving duration, day 71.61.93.21.41.41.5-1.31.3-1.31.3-0.61.71.8
Locomotion velocity, session 82.73.24.81.81.81.8-1.81.8-1.81.8-0.82.22.1
Locomotion distance, session 80.60.91.20.90.91.0-1.01.0-1.01.0-0.61.10.8
Degree of sensitization distance0.50.50.8-0.8-0.8-0.80.7-0.70.7-0.70.9-0.6-0.3
Degree of sensitization stereotypy0.10.10.50.10.10.2-0.00.0-0.00.00.40.50.7
Conditioned locomotion1.82.13.2-1.5-1.5-1.31.5-1.51.5-1.50.4-1.6-1.8
Cocaine response after cond. corrected2.93.54.5-2.1-2.1-1.91.8-1.81.8-1.81.1-2.0-1.9
Cocaine response after cond. not corrected3.44.04.7-2.1-2.1-2.12.0-2.02.0-2.01.1-2.2-2.1
Cocaine response before conditioning0.40.51.01.01.00.7-0.60.6-0.60.6-0.70.50.6
Saline control response0.81.11.4-0.9-0.9-1.01.2-1.21.2-1.20.5-1.2-1.1
Bone: connectivity density0.40.62.30.40.40.5-0.50.5-0.50.50.61.11.5
Bone: cortical apparent density1.01.32.2-1.4-1.4-1.21.1-1.11.1-1.11.5-1.0-0.5
Bone: cortical area0.40.63.0-0.5-0.5-0.30.4-0.40.4-0.41.70.31.1
Bone: cortical porosity0.10.10.40.10.10.1-0.30.3-0.30.30.40.50.7
Bone: cortical porosity0.20.20.90.00.00.0-0.10.1-0.10.10.90.50.9
Bone: cortical thickness0.91.54.5-1.2-1.2-1.11.2-1.21.2-1.22.1-0.60.3
Bone: cortical thickness1.01.21.4-1.2-1.2-1.11.1-1.11.1-1.10.8-1.2-1.0
Bone: cortical tissue density0.70.91.5-1.2-1.2-1.00.8-0.80.8-0.81.2-0.8-0.4
Condit. Reinf. active minus inactive responses2.02.22.81.41.41.5-1.71.7-1.71.7-1.41.41.0
Condit. Reinf. active-inactive response ratio0.10.10.30.20.20.2-0.40.4-0.40.4-0.60.1-0.2
Condit. Reinf. active responses3.54.45.12.02.02.2-2.32.3-2.32.3-1.52.21.8
Condit. Reinf. inactive responses2.53.04.21.81.81.9-1.71.7-1.71.7-1.02.01.8
Incentive salience index mean1.92.43.11.41.41.6-1.71.7-1.71.7-0.91.81.4
Condit. Reinf. lever presses1.21.73.41.11.11.3-1.31.3-1.31.3-0.21.81.8
Condit. Reinf. active minus inactive responses1.21.64.01.41.41.2-1.31.3-1.31.3-2.00.6-0.0
Condit. Reinf. active-inactive response ratio0.30.41.90.30.30.1-0.20.2-0.20.2-1.4-0.5-1.1
Condit. Reinf. active responses1.31.82.51.51.51.4-1.41.4-1.41.4-1.61.10.7
Condit. Reinf. inactive responses0.50.71.00.80.80.9-0.80.8-0.80.8-0.41.01.0
Condit. Reinf. lever presses1.62.24.31.61.61.6-1.51.5-1.51.5-2.10.80.4
Condit. Reinf. lever reinforcers received0.81.12.11.11.11.1-1.11.1-1.11.1-1.50.70.3
Conditioned reinforcement - actives0.10.10.6-0.7-0.7-0.20.1-0.10.1-0.10.3-0.10.1
Conditioned reinforcement - inactives0.71.01.6-1.3-1.3-1.10.9-0.90.9-0.90.7-1.0-0.9
Conditioned locomotion1.72.22.91.21.21.5-1.71.7-1.71.7-1.11.51.6
Patch foraging indifference point 0 sec2.54.78.2-2.3-2.3-2.22.2-2.22.2-2.22.9-1.6-0.7
Patch foraging indifference point AUC0.50.81.30.80.80.9-1.01.0-1.01.0-1.20.60.2
Delay disc. indifference point, 0s delay0.50.52.8-0.6-0.6-0.40.4-0.40.4-0.41.70.40.8
Delay disc. indifference point, 16s delay0.20.20.30.60.60.4-0.40.4-0.40.4-0.40.40.4
Delay disc. indifference point, 2s delay0.10.10.5-0.1-0.1-0.0-0.10.1-0.10.10.70.10.4
Delay disc. indifference point, 24s delay0.20.20.3-0.3-0.3-0.50.5-0.50.5-0.50.4-0.4-0.3
Delay disc. indifference point, 4s delay0.70.81.30.80.80.9-0.90.9-0.90.9-0.21.11.1
Delay disc. indifference point, 8s delay0.30.30.7-0.7-0.7-0.30.5-0.50.5-0.50.1-0.5-0.8
Indifference point function ln k0.10.20.2-0.4-0.4-0.30.5-0.50.5-0.50.5-0.4-0.2
Indifference point function log k0.10.20.2-0.4-0.4-0.30.5-0.50.5-0.50.5-0.4-0.2
Patch foraging total patch changes 0 sec2.24.27.2-2.2-2.2-2.12.1-2.12.1-2.12.7-1.6-0.7
Patch foraging total patch changes 12 sec2.02.63.1-1.8-1.8-1.71.7-1.71.7-1.71.4-1.6-1.2
Patch foraging total patch changes 18 sec0.00.00.1-0.1-0.1-0.10.1-0.10.1-0.10.2-0.00.1
Patch foraging total patch changes 24 sec0.20.30.9-0.5-0.5-0.60.6-0.60.6-0.60.9-0.40.1
Patch foraging total patch changes 6 sec1.52.23.7-1.6-1.6-1.61.6-1.61.6-1.61.9-1.0-0.4
Patch foraging time to switch 0 sec0.10.20.6-0.2-0.2-0.30.4-0.40.4-0.40.80.20.5
Patch foraging water rate 0 sec0.61.31.9-1.2-1.2-1.21.0-1.01.0-1.00.6-1.4-1.3
Patch foraging water rate 12 sec0.91.82.8-1.4-1.4-1.41.3-1.31.3-1.30.8-1.7-1.5
Patch foraging water rate 18 sec0.91.34.6-0.9-0.9-0.90.8-0.80.8-0.8-0.6-1.8-2.2
Patch foraging water rate 24 sec3.65.19.4-2.3-2.3-2.22.1-2.12.1-2.10.6-2.9-3.1
Patch foraging water rate 6 sec0.20.31.3-0.0-0.0-0.1-0.00.0-0.00.0-1.0-0.8-1.1
Seeking ratio, delayed vs. immediate footshock1.31.62.01.21.21.4-1.41.4-1.41.4-0.80.91.4
Distance traveled before self-admin1.31.71.91.41.41.4-1.41.4-1.41.4-1.31.00.8
Distance traveled after self-admin0.00.00.10.20.20.20.1-0.10.1-0.1-0.30.1-0.0
Extensor digitorum longus weight5.722.325.6-5.1-5.1-5.04.9-4.94.9-4.94.2-4.6-3.7
Bone: elastic displacement0.00.00.0-0.0-0.0-0.10.0-0.00.0-0.00.1-0.10.1
Bone: elastic work0.40.61.7-0.7-0.7-0.70.7-0.70.7-0.71.3-0.40.2
Bone: endosteal estimation0.20.52.0-0.7-0.7-0.60.6-0.60.6-0.61.4-0.20.4
Bone: endosteal perimeter0.71.42.41.21.21.2-1.21.2-1.21.2-0.21.41.5
Epididymis fat weight0.10.21.0-0.3-0.3-0.10.0-0.00.0-0.0-0.6-0.7-1.0
Delta time in closed arm before/after self-admin3.93.66.6-2.0-2.0-2.01.7-1.71.7-1.70.7-2.6-2.3
Delta time in open arm before/after self-admin0.70.71.0-0.7-0.7-0.71.0-1.01.0-1.00.7-0.5-0.6
Diff in mean of infusions in LGA sessions1.41.62.41.31.31.3-1.31.3-1.31.3-1.61.00.6
Delay discount exponential model param0.00.00.0-0.0-0.0-0.20.1-0.10.1-0.10.0-0.1-0.0
Extinction: sum of active levers before priming0.70.82.30.80.80.8-1.01.0-1.01.0-1.50.3-0.2
Active lever presses in extinction session 60.40.40.50.60.60.6-0.70.7-0.70.7-0.30.70.5
Bone: final force1.42.37.0-1.4-1.4-1.31.5-1.51.5-1.52.6-0.40.5
Bone: final moment1.42.27.0-1.4-1.4-1.31.5-1.51.5-1.52.6-0.40.5
Food consumed during 24 hour testing period0.30.40.5-0.6-0.6-0.70.6-0.60.6-0.60.7-0.6-0.3
Glucose1.21.92.3-1.3-1.3-1.41.5-1.51.5-1.51.4-1.2-0.9
Heart weight0.10.10.70.10.10.2-0.30.3-0.30.3-0.8-0.1-0.4
Delay discount hyperbolic model param0.00.00.10.10.1-0.0-0.10.1-0.10.1-0.4-0.0-0.1
Intermittent access intake day 1-15 change0.10.20.90.10.10.3-0.40.4-0.40.4-1.0-0.3-0.3
Intermittent access intake escalation0.10.20.90.10.10.2-0.30.3-0.30.3-0.9-0.3-0.4
Intermittent access intake escalation 20.40.51.50.70.70.7-0.70.7-0.70.7-1.20.20.0
Intermitt. access day 1 inactive lever presses0.10.31.30.10.1-0.1-0.10.1-0.10.1-1.1-0.5-1.1
Intermitt. access day 15 inactive lever presses0.40.81.20.90.90.8-1.01.0-1.01.0-1.10.70.1
Intermitt. access escalation Index0.10.20.60.50.50.3-0.10.1-0.10.10.40.50.8
Intermittent access day 1 total infusions0.20.30.4-0.6-0.6-0.70.4-0.40.4-0.40.4-0.5-0.4
Intermittent access day 15 total infusions0.00.00.0-0.2-0.2-0.2-0.00.0-0.00.00.2-0.20.1
Intermittent access terminal intake (last 3 days)0.10.10.40.20.20.3-0.40.4-0.40.40.20.40.7
Intermittent access total infusions0.10.10.4-0.5-0.5-0.40.2-0.20.2-0.20.6-0.10.1
Intermittent access day 1 locomotion0.30.40.7-0.6-0.6-0.70.6-0.60.6-0.6-0.1-0.6-0.8
Intermittent access day 15 total locomotion0.00.10.3-0.2-0.20.0-0.20.2-0.20.2-0.5-0.2-0.2
Intermittent access total locomotion0.00.00.1-0.3-0.30.0-0.10.1-0.10.1-0.3-0.1-0.1
Intermittent access standard deviation0.51.11.21.11.10.9-1.11.1-1.11.1-0.81.01.0
Left kidney weight0.00.10.2-0.2-0.2-0.10.2-0.20.2-0.2-0.3-0.3-0.5
Right kidney weight0.10.31.30.30.30.5-0.50.5-0.50.5-1.10.1-0.3
Cocaine induced anxiety2.13.03.51.81.81.8-1.81.8-1.81.8-0.91.61.9
Post-drug Anxiety2.22.44.61.61.61.5-1.61.6-1.61.6-0.21.32.1
Baseline Anxiety0.00.00.00.00.0-0.10.1-0.10.1-0.10.2-0.2-0.0
Tail length2.710.514.93.53.53.5-3.33.3-3.33.3-3.92.61.5
Length with tail0.93.97.92.22.22.0-1.91.9-1.91.9-2.81.30.4
Length without tail0.41.21.4-1.0-1.0-1.11.2-1.21.2-1.20.6-1.1-1.0
Times rat made contact with spout1.51.71.9-1.3-1.3-1.41.3-1.31.3-1.30.9-1.3-1.3
Lifetime Intake0.50.61.7-0.9-0.9-0.80.7-0.70.7-0.71.3-0.50.0
Liver weight, left0.40.71.1-1.1-1.1-0.90.8-0.80.8-0.80.8-0.9-0.6
Liver weight, right0.10.10.40.30.30.2-0.20.2-0.20.2-0.7-0.1-0.4
Locomotor activity3.55.57.02.72.72.5-2.32.3-2.32.3-2.02.32.0
Locomotor testing distance1.52.73.41.81.81.7-1.61.6-1.61.6-1.31.61.5
Locomotor testing rearing0.00.10.10.00.0-0.10.2-0.20.2-0.2-0.3-0.2-0.4
Locomotion in novel chamber0.00.10.2-0.1-0.1-0.40.2-0.20.2-0.20.2-0.3-0.0
Locomotion in novel chamber post-restriction3.35.56.82.62.62.5-2.52.5-2.52.5-2.61.61.3
Fecal boli incidents, locomotor time 10.91.31.7-0.9-0.9-1.21.3-1.31.3-1.30.5-1.3-1.3
Change in fecal boli incidents, locomotor task1.51.42.51.31.31.2-1.11.1-1.11.1-0.31.51.6
Time >=10cm from walls, locomotor time 10.20.21.0-0.2-0.2-0.30.3-0.30.3-0.31.00.40.8
Bouts of movement, locomotor time 10.50.50.80.70.70.8-0.70.7-0.70.7-0.90.70.2
Total resting periods, locomotor time 11.11.31.71.21.21.2-1.21.2-1.21.2-1.31.00.5
Rest time, locomotor task time 10.70.91.31.21.21.0-0.90.9-0.90.9-0.71.10.9
Distance moved, locomotor task time 10.30.41.6-0.6-0.6-0.50.4-0.40.4-0.41.30.20.7
Vertical activity count, locomotor time 10.71.72.9-1.7-1.7-1.41.2-1.21.2-1.21.3-1.2-0.7
Time >=10cm from walls, locomotor time 20.91.41.7-1.2-1.2-1.21.2-1.21.2-1.21.0-1.3-1.1
Bouts of movement, locomotor time 20.40.61.70.80.80.7-0.60.6-0.60.6-0.11.31.1
Total resting periods, locomotor time 20.50.82.20.90.90.8-0.70.7-0.70.70.01.51.3
Rest time, locomotor task time 20.40.50.90.90.90.7-0.50.5-0.50.5-0.01.00.9
Distance moved, locomotor task time 20.30.30.6-0.7-0.7-0.50.5-0.50.5-0.5-0.1-0.6-0.8
Vertical activity count, locomotor time 21.82.43.1-1.8-1.8-1.81.5-1.51.5-1.50.8-1.8-1.7
Light reinforcement 12.66.47.62.82.82.7-2.62.6-2.62.6-2.22.41.9
Light reinforcement 20.81.31.71.31.31.2-1.11.1-1.11.1-1.01.10.8
Bone: marrow area0.20.41.8-0.7-0.7-0.60.6-0.60.6-0.61.3-0.20.3
Bone: maximum diameter1.01.83.61.21.21.3-1.31.3-1.31.3-0.11.61.9
Bone: maximum force1.42.67.1-1.6-1.6-1.41.7-1.71.7-1.72.7-0.70.3
Bone: maximum moment1.52.67.1-1.6-1.6-1.51.7-1.71.7-1.72.7-0.70.2
Mean time between licks in bursts0.30.81.20.70.71.0-1.11.1-1.11.1-1.00.50.3
Mean num. licks in bursts0.50.71.11.01.00.8-0.80.8-0.80.8-0.80.90.7
Cd content in liver0.30.40.70.30.30.5-0.80.8-0.80.8-0.30.40.4
Co content in liver1.92.24.01.51.51.5-1.61.6-1.61.6-2.01.00.4
Cu content in liver0.20.21.1-0.2-0.2-0.20.1-0.10.1-0.11.10.41.0
Fe content in liver0.30.40.6-0.8-0.8-0.70.6-0.60.6-0.60.4-0.5-0.6
K content in liver1.11.11.61.11.11.1-1.01.0-1.01.0-0.61.21.3
Mg content in liver1.51.61.81.31.31.3-1.31.3-1.31.3-1.01.31.1
Mn content in liver3.63.97.41.91.92.0-1.91.9-1.91.9-0.62.62.7
Na content in liver0.10.10.30.00.00.20.1-0.10.1-0.10.40.40.6
Rb content in liver0.20.21.20.10.1-0.1-0.10.1-0.10.10.90.51.1
Se content in liver0.00.00.00.00.00.2-0.20.2-0.20.2-0.10.20.0
Sr content in liver0.10.10.2-0.1-0.10.1-0.20.2-0.20.2-0.4-0.3-0.4
Zn content in liver1.31.55.01.21.21.1-1.21.2-1.21.2-2.20.2-0.7
Bone: minimum diameter0.10.21.2-0.1-0.1-0.0-0.00.0-0.00.01.10.41.0
Time in familiar zone, hab. session 13.63.46.12.12.11.9-1.91.9-1.91.9-2.51.30.6
Time in novel zone, hab. session 11.91.95.3-1.5-1.5-1.31.3-1.31.3-1.32.3-0.60.3
Total zone transitions, hab. session 11.11.62.81.21.21.3-1.21.2-1.21.2-0.31.61.7
Total locomotion distance, hab. session 13.54.97.62.22.22.2-2.22.2-2.22.2-0.92.72.8
Locomotion velocity, hab. session 13.24.66.42.22.22.2-2.12.1-2.12.1-1.12.52.4
Time in familiar zone, hab. session 23.13.36.81.81.81.8-1.91.9-1.91.9-2.61.00.2
Time in novel zone, hab. session 23.23.27.7-1.8-1.8-1.81.9-1.91.9-1.92.8-0.9-0.0
Total zone transitions, hab. session 20.30.41.9-0.0-0.00.00.1-0.10.1-0.11.30.81.4
Total locomotion distance, hab. session 20.91.22.21.21.21.1-1.01.0-1.01.0-0.31.51.4
Locomotion velocity, hab. session 21.21.73.11.31.31.3-1.11.1-1.11.1-0.31.81.8
Novel to familiar place preference ratio1.31.44.4-1.2-1.2-1.11.2-1.21.2-1.22.1-0.40.5
Novelty place preference0.80.93.1-0.9-0.9-0.80.8-0.80.8-0.81.8-0.20.6
Time in novel zone, NPP test1.21.34.0-1.2-1.2-1.11.1-1.11.1-1.12.0-0.40.4
Total zone transitions, NPP test0.10.20.7-0.1-0.1-0.10.3-0.30.3-0.30.90.40.6
Total locomotion distance, NPP test0.20.31.20.40.40.5-0.30.3-0.30.30.51.01.1
Locomotion velocity, NPP test0.40.61.40.70.70.8-0.60.6-0.60.60.11.21.2
Intraocular pressure0.20.31.50.10.10.0-0.10.1-0.10.1-1.1-0.7-1.2
Delta distance traveled before/after self-admin0.70.71.0-0.8-0.8-0.81.0-1.01.0-1.00.6-0.8-0.6
Delta ambulatory time before/after self-admin0.40.40.7-0.6-0.6-0.60.8-0.80.8-0.80.8-0.4-0.1
Parametrial fat weight0.20.61.1-0.7-0.7-0.80.8-0.80.8-0.81.1-0.5-0.1
Pavlov. Cond. lever latency0.70.92.1-0.6-0.6-0.90.9-0.90.9-0.9-0.2-1.3-1.4
Pavlov. Cond. magazine entry latency1.41.82.51.21.21.4-1.61.6-1.61.6-1.31.20.7
Pavlov. Cond. change in total contacts0.10.10.4-0.5-0.5-0.30.1-0.10.1-0.10.6-0.1-0.0
Pavlov. Cond. index score0.81.11.40.80.81.0-1.21.2-1.21.2-0.51.21.0
Pavlov. Cond. latency score1.11.42.01.01.01.2-1.31.3-1.31.3-0.41.41.4
Pavlov. Cond. lever contacts0.40.51.40.30.30.6-0.70.7-0.70.70.41.01.2
Pavlov. Cond. magazine entry number0.60.81.1-0.7-0.7-0.91.1-1.11.1-1.10.9-0.7-0.3
Pavlov. Cond. intertrial magazine entries0.10.10.6-0.1-0.1-0.10.2-0.20.2-0.2-0.4-0.5-0.8
Pavlov. Cond. lever-magazine prob. diff.0.91.11.50.80.81.1-1.21.2-1.21.2-0.61.21.0
Pavlov. Cond. response bias0.60.71.10.60.60.9-1.01.0-1.01.0-0.80.80.4
Pavlov. Cond. lever latency1.42.02.6-1.6-1.6-1.61.4-1.41.4-1.41.5-1.0-0.8
Pavlov. Cond. magazine entry latency2.32.83.31.81.81.8-1.81.8-1.81.8-1.61.41.0
Pavlov. Cond. change in total contacts0.40.71.10.90.90.9-0.90.9-0.90.9-1.10.60.3
Pavlov. Cond. index score1.62.22.71.61.61.6-1.61.6-1.61.6-1.61.10.8
Pavlov. Cond. latency score2.02.73.41.91.91.8-1.71.7-1.71.7-1.71.31.0
Pavlov. Cond. lever contacts1.21.62.41.41.41.4-1.31.3-1.31.3-1.50.80.5
Pavlov. Cond. magazine entry number2.32.83.3-1.8-1.8-1.81.8-1.81.8-1.81.6-1.4-1.1
Pavlov. Cond. intertrial magazine entries1.32.02.3-1.4-1.4-1.41.5-1.51.5-1.51.0-1.4-1.2
Pavlov. Cond. lever-magazine prob. diff.2.02.63.11.71.71.7-1.71.7-1.71.7-1.61.31.0
Pavlov. Cond. response bias1.82.43.61.71.71.6-1.71.7-1.71.7-1.90.90.6
Time in closed arm before self-admin0.10.10.80.20.20.2-0.10.1-0.10.10.50.50.9
Time in closed arm after self-admin0.60.71.6-0.8-0.8-0.80.8-0.80.8-0.80.8-1.3-0.5
Time in open arm before self-admin0.00.00.0-0.1-0.1-0.1-0.10.1-0.10.10.00.1-0.0
Time in open arm after self-admin1.71.82.5-1.3-1.3-1.31.6-1.61.6-1.61.0-0.8-1.2
Bone: periosteal estimation0.30.74.0-0.6-0.6-0.50.5-0.50.5-0.52.00.21.1
Bone: periosteal perimeter0.40.72.60.60.60.6-0.70.7-0.70.70.71.21.6
Bone: post-yield work0.40.50.8-0.9-0.9-0.70.8-0.80.8-0.80.9-0.6-0.3
Progressive ratio test 1 active lever presses0.40.60.9-0.9-0.9-0.80.7-0.70.7-0.70.8-0.6-0.5
Progressive ratio test 1 breakpoint0.50.60.9-0.9-0.9-0.90.7-0.70.7-0.70.8-0.7-0.5
Progressive ratio test 1 inactive lever presses0.10.20.30.40.40.3-0.50.5-0.50.5-0.20.30.3
Progressive ratio test 2 active lever presses0.00.00.1-0.0-0.00.1-0.20.2-0.20.2-0.00.30.2
Progressive ratio test 2 breakpoint0.10.10.20.10.10.2-0.30.3-0.30.3-0.20.40.3
Progressive ratio test 2 inactive lever presses0.10.10.5-0.4-0.4-0.20.0-0.00.0-0.00.70.20.5
Incentive Sensitization - Responses0.20.30.50.50.50.5-0.50.5-0.50.5-0.70.60.2
Incentive Sensitization - Breakpoint0.40.50.70.70.70.7-0.70.7-0.70.7-0.80.80.4
Sum of active levers in priming session hrs 5-60.10.10.20.30.30.3-0.30.3-0.30.3-0.4-0.1-0.0
Progressive ratio1.32.02.5-1.4-1.4-1.51.6-1.61.6-1.61.0-1.1-1.1
Food seeking constrained by brief footshock1.72.13.31.61.61.6-1.51.5-1.51.5-1.81.10.5
Seeking ratio, punishment vs. effort2.43.44.11.91.92.0-2.02.0-2.02.0-2.01.20.9
Retroperitoneal fat weight2.611.112.5-3.3-3.3-3.53.5-3.53.5-3.52.5-3.4-2.9
Reaction time number correct1.02.02.6-1.4-1.4-1.41.4-1.41.4-1.40.6-1.6-1.6
Reaction time mean minus median0.71.82.21.51.51.3-1.41.4-1.41.4-1.41.00.9
Reaction time mean minus median AUC1.43.74.22.02.01.9-2.02.0-2.02.0-1.12.02.1
Reaction time num false alarms0.81.11.5-1.0-1.0-1.01.2-1.21.2-1.20.9-0.7-0.7
Reaction time num false alarms AUC0.91.41.8-1.1-1.1-1.11.3-1.31.3-1.30.8-1.0-1.0
Reaction time trials correct on left1.02.02.6-1.4-1.4-1.41.4-1.41.4-1.40.6-1.6-1.6
Reaction time trials on left1.01.82.3-1.4-1.4-1.41.4-1.41.4-1.40.6-1.5-1.5
Reaction time mean1.72.63.21.61.61.6-1.81.8-1.81.8-1.01.51.6
Reaction time mean AUC0.91.51.81.11.11.2-1.31.3-1.31.3-0.61.11.3
Median of all reaction times1.21.72.21.21.21.3-1.51.5-1.51.5-0.71.31.4
Reaction time omissions0.10.20.70.30.30.4-0.40.4-0.40.40.20.40.9
Reaction time false alarm rate0.10.20.3-0.3-0.3-0.30.5-0.50.5-0.50.6-0.10.0
Reaction time premature initiation rate0.60.93.41.01.00.9-0.80.8-0.80.8-1.80.5-0.3
Reaction time premature initiations0.20.42.20.20.20.20.0-0.00.0-0.0-1.5-0.5-1.2
Std. dev. reaction times0.91.72.01.31.31.3-1.41.4-1.41.4-0.91.21.2
Reaction time trials completed1.01.82.3-1.4-1.4-1.41.4-1.41.4-1.40.6-1.5-1.5
Reaction time trials AUC1.22.33.1-1.6-1.6-1.51.6-1.61.6-1.60.6-1.7-1.8
Run reversals in cocaine runway, females3.93.95.02.02.02.0-2.02.0-2.02.0-1.62.21.7
Run reversals in cocaine runway, males3.23.23.71.91.91.9-1.91.9-1.91.9-1.21.51.7
Latency to leave start box in cocaine runway0.30.31.40.30.30.6-0.30.3-0.30.30.60.81.2
Latency to leave start box in cocaine runway, F0.60.72.50.50.50.8-0.40.4-0.40.40.81.21.6
Latency to leave start box in cocaine runway, M0.10.10.2-0.4-0.4-0.30.3-0.30.3-0.3-0.1-0.5-0.5
Std. dev. time between licks in bursts1.21.62.51.21.21.2-1.31.3-1.31.3-0.51.31.6
Total sessions with >9 infusions0.50.62.0-0.7-0.7-0.80.7-0.70.7-0.71.4-0.60.2
Short access day 1 total inactive lever presses0.10.10.40.30.30.3-0.30.3-0.30.3-0.60.0-0.2
Short access day 10 total inactive lever presses0.10.31.7-0.2-0.2-0.50.3-0.30.3-0.3-0.6-0.8-1.3
Short access day 1 total infusions0.50.61.9-0.8-0.8-0.80.7-0.70.7-0.71.4-0.60.1
Short access day 10 total infusions0.20.20.4-0.4-0.4-0.60.5-0.50.5-0.50.6-0.4-0.2
Short access total infusions0.70.82.5-0.9-0.9-0.90.9-0.90.9-0.91.6-0.50.1
Short access day 1 locomotion0.10.10.10.20.20.2-0.30.3-0.30.3-0.30.00.1
Short access day 10 total locomotion0.40.74.00.50.50.7-0.60.6-0.60.6-2.00.1-0.5
Short access total locomotion0.00.00.20.10.10.1-0.20.2-0.20.2-0.5-0.1-0.1
One hour access (0.3 mA shock)0.20.30.6-0.8-0.8-0.50.4-0.40.4-0.40.3-0.5-0.5
Compulsive drug intake0.00.00.10.20.20.3-0.10.1-0.10.1-0.00.20.3
One hour access (shock baseline)0.00.00.1-0.2-0.2-0.1-0.10.1-0.10.1-0.2-0.0-0.2
Social response proportion1.21.32.01.41.41.3-1.01.0-1.01.0-1.21.40.9
Social responses9.712.516.14.04.03.8-3.53.5-3.53.5-3.53.52.6
Social time1.21.72.0-1.2-1.2-1.41.4-1.41.4-1.40.9-1.2-1.2
Soleus weight5.416.018.2-4.2-4.2-4.24.2-4.24.2-4.24.3-3.5-2.3
Bone: stiffness2.54.08.4-2.1-2.1-1.92.1-2.12.1-2.12.9-1.1-0.2
Tibialis anterior weight1.24.14.8-2.2-2.2-2.22.1-2.12.1-2.12.1-1.9-1.2
Time to tail flick, vehicle, before self-admin1.71.72.01.41.41.4-1.41.4-1.41.4-0.80.81.4
Time to tail flick, vehicle, after self-admin0.20.31.80.30.30.3-0.10.1-0.10.1-1.3-0.2-1.0
Time to tail flick, test, before self-admin1.41.42.41.11.11.1-1.21.2-1.21.2-0.31.41.5
Time to tail flick, test, after self-admin0.10.10.30.20.20.2-0.10.1-0.10.10.20.20.5
Delta time to tail flick, vehicle, before/after SA2.01.93.8-1.3-1.3-1.31.5-1.51.5-1.50.2-1.2-2.0
Delta time to tail flick, test, before/after SA0.50.51.5-0.5-0.5-0.50.6-0.60.6-0.6-0.4-1.0-1.2
Tibia length0.72.03.41.51.51.4-1.51.5-1.51.5-1.81.10.4
Ambulatory time before self-admin0.30.40.50.70.70.7-0.70.7-0.70.7-0.70.50.3
Ambulatory time after self-admin0.00.00.00.10.10.10.1-0.10.1-0.1-0.10.00.0
Bone: tissue strength4.04.07.1-2.0-2.0-2.02.1-2.12.1-2.12.7-1.4-0.6
Total heroin consumption2.52.93.51.91.91.9-1.71.7-1.71.7-1.61.61.3
Bone: trabecular number0.91.63.21.11.11.4-1.21.2-1.21.2-0.31.61.8
Bone: trabecular spacing1.41.95.5-1.1-1.1-1.41.2-1.21.2-1.2-0.3-1.9-2.3
Bone: trabecular thickness1.72.18.51.01.01.0-0.90.9-0.90.91.32.12.9
Bone: trabecular tissue density5.17.58.5-2.9-2.9-2.82.9-2.92.9-2.92.5-2.6-2.0
Water consumed over 24 hours0.30.41.4-0.5-0.5-0.60.6-0.60.6-0.61.2-0.20.3
Number of responses in last shaping day0.80.92.20.70.70.9-1.11.1-1.11.1-1.50.40.3