Hub : Genes

Epn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC intron excision ratio chr1_77786232_77787609 0.1 0.07 1.9e-03 0.01 0.01 -0.01 0 7.2e-02 1.6e-01 9.2e-01 2.5e-01
2 BLA intron excision ratio chr1_77773661_77773795 0.19 0.23 1.3e-03 0.03 0.03 0.01 0.03 9.1e-03 1.5e-02 5.8e-02 1.4e-02
3 BLA intron excision ratio chr1_77773664_77773795 0.17 0.2 9.7e-04 0.03 0.03 0.02 0.03 6.3e-03 1.1e-02 4.6e-02 8.7e-03
4 NAcc intron excision ratio chr1_77786232_77789209 0.01 0.01 8.0e-03 0 0.01 0 0 6.7e-02 2.7e-02 5.0e-02 5.4e-02
5 NAcc gene expression Epn1 0.02 0.02 8.7e-04 0.01 0.01 0.01 0.01 2.5e-02 5.9e-03 3.2e-02 1.1e-02
6 Brain intron excision ratio chr1_77786232_77789209 0.03 0.03 2.8e-04 0.03 0.03 0.03 0.03 5.0e-04 1.3e-03 2.0e-03 1.4e-03
7 Brain gene expression Epn1 0.06 0.04 3.8e-06 0.04 0.06 0.02 0.04 2.9e-04 5.2e-06 3.0e-03 1.7e-04
8 pVTA intron excision ratio chr1_77786232_77789048 0.04 0.04 8.8e-03 0.01 0.01 0 0.01 6.8e-02 9.7e-02 1.8e-01 8.9e-02
9 PL intron excision ratio chr1_77786232_77789048 0.03 0.03 8.7e-03 0.01 0 0.01 0.01 6.9e-02 7.4e-02 8.5e-03 5.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.20.30.3-0.40.4-0.50.4-0.20.6-0.4-0.5
Area under the delay curve0.60.71.1-0.70.7-0.70.7-0.71.0-0.61.01.1
BMI with tail0.51.82.4-1.51.5-1.51.4-1.31.1-1.41.20.9
BMI without tail0.10.20.30.5-0.50.5-0.40.6-0.20.00.2-0.3
Body weight0.93.95.92.3-2.02.0-2.12.3-2.41.5-1.6-1.3
Weight adjusted by age0.40.71.50.7-0.70.7-0.90.6-0.51.2-1.20.0
Bone surface3.05.46.62.5-2.42.4-2.42.4-2.62.2-2.1-1.9
Bone volume2.54.45.22.1-2.12.1-2.32.2-2.12.1-1.9-1.9
Breakpoint value in progressive ratio session0.30.40.7-0.80.8-0.80.8-0.7-0.1-0.70.30.0
Number of licking bursts0.10.10.2-0.30.3-0.30.4-0.30.1-0.40.40.2
Context. condit. distance diff. score0.30.31.2-0.40.5-0.50.5-0.8-0.0-0.2-0.51.1
Locomotion velocity, session 10.60.71.8-0.40.1-0.10.0-0.80.91.0-1.31.3
Locomotion distance, session 12.43.07.51.4-1.71.7-1.71.1-1.52.3-2.7-0.4
Locomotion velocity, session 20.10.20.4-0.60.3-0.30.3-0.60.60.2-0.30.3
Locomotion distance, session 21.62.34.01.5-1.81.8-1.71.4-0.92.0-1.5-0.4
Locomotion velocity, session 30.10.10.2-0.30.2-0.20.2-0.30.10.0-0.5-0.3
Locomotion distance, session 30.30.31.30.3-0.40.4-0.40.2-0.50.8-1.1-0.2
Stereotopy head waving bouts, day 30.10.20.3-0.30.5-0.50.4-0.3-0.3-0.5-0.3-0.3
Stereotopy head waving duration, day 30.10.10.3-0.30.5-0.50.4-0.3-0.2-0.5-0.2-0.3
Locomotion velocity, session 70.20.21.20.1-0.10.1-0.20.0-0.40.5-1.1-0.3
Locomotion distance, session 70.10.10.5-0.10.2-0.2-0.1-0.20.30.6-0.30.7
Stereotopy head waving bouts, day 70.40.51.50.5-0.40.4-0.30.4-1.20.0-0.8-1.2
Stereotopy head waving duration, day 70.30.41.40.5-0.30.3-0.30.5-1.10.0-0.7-1.2
Locomotion velocity, session 80.20.21.2-0.30.1-0.10.0-0.4-0.20.5-1.10.1
Locomotion distance, session 80.20.31.00.3-0.40.4-0.3-0.1-0.30.8-1.00.9
Degree of sensitization distance0.00.00.10.10.1-0.1-0.0-0.0-0.10.1-0.00.3
Degree of sensitization stereotypy0.20.20.60.2-0.20.2-0.00.2-0.7-0.2-0.3-0.8
Conditioned locomotion0.10.10.8-0.10.1-0.1-0.1-0.2-0.50.4-0.90.0
Cocaine response after cond. corrected1.51.84.5-1.31.2-1.21.2-0.81.5-1.72.1-0.3
Cocaine response after cond. not corrected0.20.31.00.3-0.50.5-0.30.70.2-0.10.7-1.0
Cocaine response before conditioning6.88.110.13.1-3.23.2-3.02.7-2.83.0-2.9-1.1
Saline control response0.40.53.5-0.30.3-0.3-0.1-0.3-0.60.7-1.9-0.3
Bone: connectivity density0.00.00.1-0.30.2-0.20.1-0.10.3-0.10.2-0.1
Bone: cortical apparent density0.20.31.1-0.0-0.10.1-0.40.11.10.80.30.7
Bone: cortical area0.81.32.41.3-1.01.0-1.11.0-1.60.9-1.4-0.7
Bone: cortical porosity0.50.51.5-0.80.7-0.70.6-0.5-0.4-0.80.2-1.2
Bone: cortical porosity0.40.52.7-0.30.2-0.20.2-0.0-1.0-0.5-0.2-1.6
Bone: cortical thickness0.20.40.7-0.80.9-0.90.7-0.80.4-0.4-0.10.1
Bone: cortical thickness0.10.10.30.2-0.30.3-0.40.20.40.50.40.5
Bone: cortical tissue density0.20.31.2-0.0-0.10.1-0.30.11.10.70.40.7
Condit. Reinf. active minus inactive responses0.20.20.3-0.50.5-0.50.5-0.4-0.1-0.4-0.2-0.6
Condit. Reinf. active-inactive response ratio1.61.72.2-1.41.5-1.51.5-1.41.0-1.51.00.6
Condit. Reinf. active responses0.40.51.70.3-0.50.5-0.40.4-1.00.4-1.1-1.3
Condit. Reinf. inactive responses3.84.66.42.0-2.22.2-2.21.9-2.32.2-2.5-1.7
Incentive salience index mean0.10.10.30.2-0.30.3-0.30.2-0.40.3-0.6-0.5
Condit. Reinf. lever presses0.60.91.41.0-1.01.0-1.21.0-0.41.2-0.5-0.4
Condit. Reinf. active minus inactive responses3.44.46.52.3-2.12.1-2.22.2-2.62.0-1.8-1.2
Condit. Reinf. active-inactive response ratio5.26.08.12.8-2.62.6-2.72.8-2.62.3-1.4-1.7
Condit. Reinf. active responses2.73.87.02.1-1.91.9-1.91.7-2.72.0-2.2-0.8
Condit. Reinf. inactive responses0.20.31.2-0.00.0-0.00.2-0.4-0.90.0-1.10.3
Condit. Reinf. lever presses0.71.03.41.0-0.90.9-0.71.0-1.80.1-0.7-1.0
Condit. Reinf. lever reinforcers received3.65.08.62.4-2.22.2-2.22.0-2.92.3-2.5-0.9
Conditioned reinforcement - actives0.20.30.40.6-0.60.6-0.70.60.60.6-0.2-0.1
Conditioned reinforcement - inactives1.92.84.42.1-1.91.9-2.11.8-0.52.1-1.1-0.3
Conditioned locomotion0.10.10.20.4-0.40.4-0.40.40.10.30.3-0.0
Patch foraging indifference point 0 sec0.30.61.3-0.90.8-0.80.8-1.20.1-0.3-0.70.7
Patch foraging indifference point AUC0.40.50.8-0.90.8-0.80.8-0.80.8-0.80.50.1
Delay disc. indifference point, 0s delay0.20.20.9-0.30.3-0.30.1-0.40.50.5-0.40.9
Delay disc. indifference point, 16s delay0.70.72.5-0.60.6-0.60.9-0.50.3-1.31.6-0.3
Delay disc. indifference point, 2s delay1.21.43.8-0.90.9-0.90.7-0.81.9-0.51.41.6
Delay disc. indifference point, 24s delay0.60.72.3-0.70.7-0.70.9-0.70.5-1.11.50.3
Delay disc. indifference point, 4s delay0.10.10.10.3-0.30.3-0.20.30.30.10.30.2
Delay disc. indifference point, 8s delay0.20.20.8-0.30.3-0.30.4-0.50.6-0.20.40.9
Indifference point function ln k3.76.58.72.8-2.62.6-2.82.5-2.53.0-2.5-1.2
Indifference point function log k3.76.58.72.8-2.62.6-2.82.5-2.53.0-2.5-1.2
Patch foraging total patch changes 0 sec0.30.61.3-0.90.8-0.80.8-1.20.2-0.3-0.40.9
Patch foraging total patch changes 12 sec0.20.20.5-0.50.4-0.40.6-0.70.1-0.6-0.10.3
Patch foraging total patch changes 18 sec0.50.71.5-1.01.0-1.01.1-1.2-0.0-0.9-0.40.3
Patch foraging total patch changes 24 sec0.10.10.20.2-0.30.3-0.00.2-0.3-0.30.4-0.4
Patch foraging total patch changes 6 sec0.61.01.9-1.11.1-1.11.3-1.40.5-1.10.10.6
Patch foraging time to switch 0 sec1.63.28.0-1.51.6-1.61.9-1.11.4-2.82.6-0.3
Patch foraging water rate 0 sec0.40.81.80.8-0.80.8-0.80.4-0.71.4-1.30.6
Patch foraging water rate 12 sec1.22.64.81.7-1.61.6-1.61.0-1.42.2-2.20.5
Patch foraging water rate 18 sec0.71.12.31.0-1.01.0-1.10.7-1.01.4-1.50.0
Patch foraging water rate 24 sec0.71.01.91.0-1.01.0-1.00.8-1.11.3-1.4-0.3
Patch foraging water rate 6 sec5.37.79.03.0-3.03.0-2.93.0-2.92.6-2.5-2.1
Seeking ratio, delayed vs. immediate footshock0.30.41.6-0.10.1-0.1-0.0-0.5-0.40.7-1.30.9
Distance traveled before self-admin1.31.74.71.0-1.01.0-1.40.7-1.12.2-2.00.5
Distance traveled after self-admin0.50.61.4-0.90.9-0.90.6-1.2-0.50.1-0.41.0
Extensor digitorum longus weight0.20.61.21.1-0.70.7-0.91.0-1.00.5-0.4-0.6
Bone: elastic displacement0.40.41.2-0.70.8-0.80.5-0.7-0.2-0.2-1.1-0.4
Bone: elastic work0.50.62.10.8-0.50.5-0.80.6-0.51.0-1.5-0.0
Bone: endosteal estimation2.45.28.22.9-2.52.5-2.42.6-2.32.0-1.7-0.9
Bone: endosteal perimeter1.53.25.02.2-1.91.9-1.81.8-2.11.6-1.7-0.4
Epididymis fat weight0.10.20.60.3-0.00.00.10.4-0.3-0.80.7-0.4
Delta time in closed arm before/after self-admin0.20.21.0-0.0-0.00.00.1-0.21.0-0.00.50.5
Delta time in open arm before/after self-admin2.01.94.31.1-1.11.1-1.21.0-2.11.4-2.0-1.2
Diff in mean of infusions in LGA sessions0.10.20.6-0.10.0-0.0-0.0-0.20.60.4-0.60.8
Delay discount exponential model param0.40.51.00.5-0.50.5-0.60.6-0.90.6-1.0-1.0
Extinction: sum of active levers before priming0.10.10.2-0.40.4-0.40.3-0.4-0.3-0.10.00.4
Active lever presses in extinction session 60.30.31.3-0.10.1-0.10.20.2-0.3-0.81.1-0.6
Bone: final force1.82.84.32.1-1.91.9-2.02.0-1.01.8-1.1-0.6
Bone: final moment2.23.65.32.3-2.12.1-2.32.2-1.12.1-1.5-0.6
Food consumed during 24 hour testing period1.42.02.71.6-1.61.6-1.51.5-1.31.5-1.2-0.4
Glucose1.72.73.9-1.71.7-1.71.8-2.01.5-1.31.01.9
Heart weight1.32.03.01.7-1.71.7-1.61.7-1.01.2-0.4-1.1
Delay discount hyperbolic model param0.60.71.50.6-0.60.6-0.70.7-1.10.6-1.1-1.2
Intermittent access intake day 1-15 change0.30.71.20.9-0.90.9-1.11.1-0.80.9-0.4-0.4
Intermittent access intake escalation0.61.22.11.2-1.11.1-1.31.5-1.11.0-0.4-0.6
Intermittent access intake escalation 20.10.10.40.1-0.10.1-0.40.3-0.40.6-0.30.1
Intermitt. access day 1 inactive lever presses0.52.13.11.6-1.61.6-1.61.7-1.31.2-0.7-1.3
Intermitt. access day 15 inactive lever presses2.14.35.92.4-2.32.3-2.32.4-1.91.8-0.9-2.0
Intermitt. access escalation Index0.71.02.2-0.91.0-1.00.8-0.90.8-0.61.21.5
Intermittent access day 1 total infusions0.30.40.70.8-0.80.8-0.80.8-0.10.7-0.3-0.1
Intermittent access day 15 total infusions0.60.91.81.1-1.01.0-1.21.4-0.40.90.1-0.2
Intermittent access terminal intake (last 3 days)0.50.71.51.0-0.90.9-1.21.2-0.10.90.10.1
Intermittent access total infusions1.11.32.31.3-1.31.3-1.51.5-0.21.3-0.4-0.3
Intermittent access day 1 locomotion0.81.01.71.3-1.21.2-1.31.2-0.11.20.00.2
Intermittent access day 15 total locomotion0.51.01.91.1-1.01.0-1.21.0-0.21.4-0.50.9
Intermittent access total locomotion1.92.33.81.8-1.71.7-1.91.9-0.71.9-0.60.1
Intermittent access standard deviation0.30.71.3-0.90.9-0.90.6-0.60.8-0.50.81.1
Left kidney weight4.922.629.05.2-5.05.0-4.94.9-5.44.3-4.5-3.1
Right kidney weight5.123.129.55.4-5.35.3-4.95.1-5.34.1-4.1-3.4
Cocaine induced anxiety1.21.73.61.1-1.11.1-1.21.1-1.91.1-1.4-1.3
Post-drug Anxiety1.11.23.30.8-0.80.8-0.81.0-1.80.4-0.8-1.6
Baseline Anxiety0.60.81.1-0.90.9-0.90.9-0.71.0-1.01.00.5
Tail length3.011.714.93.9-3.73.7-3.63.7-3.53.1-2.8-2.4
Length with tail2.611.214.93.9-3.63.6-3.53.8-3.72.8-2.6-2.4
Length without tail1.23.75.72.2-2.02.0-1.92.4-2.31.1-1.2-1.7
Times rat made contact with spout0.10.10.2-0.20.2-0.20.3-0.20.1-0.50.2-0.0
Lifetime Intake0.80.91.61.1-1.11.1-1.31.30.11.1-0.2-0.1
Liver weight, left0.81.42.01.4-1.41.4-1.21.3-1.21.0-0.8-0.4
Liver weight, right0.00.10.30.2-0.10.10.1-0.2-0.6-0.0-0.40.3
Locomotor activity0.20.20.5-0.20.3-0.30.5-0.40.5-0.60.70.7
Locomotor testing distance0.10.10.40.4-0.20.2-0.00.30.1-0.40.60.1
Locomotor testing rearing0.30.61.01.0-1.01.0-0.70.7-0.80.5-0.50.1
Locomotion in novel chamber1.82.32.8-1.71.6-1.61.5-1.61.4-1.21.31.5
Locomotion in novel chamber post-restriction0.81.22.5-1.00.9-0.91.0-1.01.6-0.91.41.1
Fecal boli incidents, locomotor time 10.20.20.40.6-0.60.6-0.50.4-0.10.5-0.30.6
Change in fecal boli incidents, locomotor task3.23.24.9-1.91.9-1.91.7-1.82.2-1.41.71.5
Time >=10cm from walls, locomotor time 10.00.00.0-0.10.1-0.10.10.00.2-0.20.1-0.2
Bouts of movement, locomotor time 10.50.62.10.3-0.30.3-0.4-0.1-0.31.1-1.51.0
Total resting periods, locomotor time 10.20.31.5-0.10.1-0.10.1-0.50.20.4-0.61.2
Rest time, locomotor task time 10.91.11.91.4-1.41.4-1.21.2-0.61.0-0.40.0
Distance moved, locomotor task time 10.91.32.1-1.41.4-1.41.4-1.40.5-1.20.50.1
Vertical activity count, locomotor time 11.43.25.2-2.22.2-2.22.0-2.31.5-1.30.51.4
Time >=10cm from walls, locomotor time 20.50.70.9-0.90.9-0.90.8-0.70.9-0.90.9-0.1
Bouts of movement, locomotor time 20.00.00.10.2-0.20.2-0.10.0-0.00.1-0.00.3
Total resting periods, locomotor time 20.00.00.30.2-0.20.2-0.10.00.20.20.00.5
Rest time, locomotor task time 20.10.10.50.0-0.00.0-0.1-0.20.30.4-0.30.7
Distance moved, locomotor task time 20.10.10.2-0.50.5-0.50.4-0.4-0.1-0.40.0-0.4
Vertical activity count, locomotor time 20.20.30.7-0.60.6-0.60.6-0.70.4-0.40.10.8
Light reinforcement 10.10.41.7-0.60.4-0.4-0.1-0.50.10.8-1.3-0.0
Light reinforcement 21.31.93.3-1.71.8-1.81.3-1.51.5-0.90.60.8
Bone: marrow area2.45.28.32.9-2.52.5-2.42.6-2.32.0-1.7-1.0
Bone: maximum diameter0.91.73.21.6-1.31.3-1.21.3-1.80.8-1.3-0.6
Bone: maximum force2.64.67.02.6-2.32.3-2.42.4-1.82.1-1.8-0.9
Bone: maximum moment3.05.27.82.8-2.42.4-2.62.6-1.92.3-2.1-0.9
Mean time between licks in bursts0.30.71.1-1.01.0-1.00.7-0.91.0-0.30.50.8
Mean num. licks in bursts0.10.10.20.4-0.40.4-0.30.4-0.10.2-0.20.0
Cd content in liver1.82.02.51.6-1.61.6-1.61.5-1.51.6-1.1-0.4
Co content in liver0.60.72.50.7-0.60.6-1.20.90.21.6-0.8-0.2
Cu content in liver1.01.22.51.0-1.01.0-1.21.3-0.81.0-0.7-1.6
Fe content in liver0.30.40.90.6-0.50.5-0.70.7-0.50.6-0.5-1.0
K content in liver0.10.10.6-0.1-0.10.1-0.10.1-0.40.0-0.4-0.8
Mg content in liver0.10.10.7-0.30.2-0.20.2-0.0-0.1-0.50.2-0.8
Mn content in liver0.40.42.2-0.10.1-0.10.10.1-1.0-0.4-0.6-1.5
Na content in liver2.32.44.1-2.01.9-1.91.8-1.81.0-1.60.70.0
Rb content in liver3.64.27.21.8-2.02.0-1.92.1-2.31.4-2.0-2.7
Se content in liver1.92.23.8-1.51.8-1.81.8-1.60.7-2.01.10.6
Sr content in liver5.95.17.3-2.62.6-2.62.2-2.62.7-1.41.01.8
Zn content in liver0.60.73.1-0.60.4-0.40.7-0.30.7-1.11.7-0.1
Bone: minimum diameter3.25.97.92.7-2.62.6-2.42.3-2.82.2-2.7-1.3
Time in familiar zone, hab. session 12.32.34.51.8-1.51.5-1.71.2-0.72.1-1.21.3
Time in novel zone, hab. session 11.91.93.2-1.81.6-1.61.6-1.30.7-1.70.7-1.1
Total zone transitions, hab. session 10.81.13.40.5-0.90.9-1.10.5-0.31.9-1.8-0.0
Total locomotion distance, hab. session 10.30.41.40.2-0.40.4-0.50.00.11.2-0.90.6
Locomotion velocity, hab. session 10.20.31.10.1-0.40.4-0.50.10.11.0-0.70.4
Time in familiar zone, hab. session 22.32.44.22.0-1.91.9-1.61.9-1.51.0-0.5-0.6
Time in novel zone, hab. session 21.41.42.6-1.61.6-1.61.2-1.41.0-0.90.40.0
Total zone transitions, hab. session 22.33.06.61.5-1.81.8-1.71.2-1.82.1-2.6-0.5
Total locomotion distance, hab. session 20.20.20.8-0.0-0.20.2-0.1-0.30.00.7-0.90.8
Locomotion velocity, hab. session 20.20.20.8-0.2-0.00.0-0.0-0.40.10.6-0.90.8
Novel to familiar place preference ratio0.00.00.20.2-0.10.1-0.00.1-0.4-0.1-0.2-0.2
Novelty place preference0.10.10.40.4-0.30.3-0.30.3-0.60.2-0.4-0.3
Time in novel zone, NPP test0.10.10.40.5-0.40.4-0.30.3-0.60.2-0.4-0.1
Total zone transitions, NPP test0.30.41.00.5-0.80.8-0.50.2-0.20.9-1.00.6
Total locomotion distance, NPP test0.40.50.90.6-0.90.9-0.60.5-0.70.7-1.0-0.1
Locomotion velocity, NPP test0.40.61.50.6-0.90.9-0.60.4-0.80.8-1.2-0.1
Intraocular pressure0.10.10.6-0.40.3-0.30.1-0.00.30.0-0.3-0.8
Delta distance traveled before/after self-admin1.81.92.7-1.61.6-1.61.7-1.60.7-1.61.00.5
Delta ambulatory time before/after self-admin1.11.41.9-1.31.3-1.31.4-1.40.9-1.30.70.6
Parametrial fat weight1.94.45.2-2.02.0-2.02.3-2.12.0-2.22.22.0
Pavlov. Cond. lever latency0.10.10.3-0.40.5-0.50.3-0.30.2-0.2-0.0-0.2
Pavlov. Cond. magazine entry latency0.60.82.0-0.90.7-0.70.9-0.70.9-1.11.40.1
Pavlov. Cond. change in total contacts0.30.30.6-0.60.5-0.50.6-0.60.7-0.50.50.6
Pavlov. Cond. index score0.30.41.0-0.60.4-0.40.6-0.60.8-0.61.00.6
Pavlov. Cond. latency score0.30.41.0-0.40.3-0.30.5-0.50.7-0.61.00.8
Pavlov. Cond. lever contacts0.10.10.30.5-0.50.5-0.20.3-0.4-0.00.0-0.0
Pavlov. Cond. magazine entry number0.20.30.90.5-0.40.4-0.50.4-0.60.7-0.9-0.2
Pavlov. Cond. intertrial magazine entries0.30.42.4-0.40.3-0.30.2-0.6-0.20.5-1.50.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.60.5-0.50.6-0.60.7-0.70.90.5
Pavlov. Cond. response bias0.10.10.5-0.0-0.10.10.10.10.2-0.40.7-0.2
Pavlov. Cond. lever latency0.20.30.60.7-0.80.8-0.60.50.20.7-0.20.2
Pavlov. Cond. magazine entry latency0.60.81.4-0.91.1-1.11.0-0.80.4-1.20.60.1
Pavlov. Cond. change in total contacts0.30.51.30.20.0-0.0-0.40.4-1.20.4-1.1-1.0
Pavlov. Cond. index score0.10.20.6-0.30.4-0.40.2-0.0-0.5-0.4-0.2-0.8
Pavlov. Cond. latency score0.30.40.7-0.70.8-0.80.6-0.4-0.1-0.80.2-0.5
Pavlov. Cond. lever contacts0.10.20.3-0.40.5-0.50.3-0.1-0.5-0.4-0.0-0.6
Pavlov. Cond. magazine entry number0.40.50.80.8-0.90.9-0.70.6-0.50.8-0.8-0.2
Pavlov. Cond. intertrial magazine entries2.84.25.12.2-2.32.3-2.22.1-2.12.1-1.6-1.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.3-0.40.5-0.50.3-0.1-0.3-0.40.0-0.6
Pavlov. Cond. response bias0.30.41.00.3-0.20.2-0.40.5-1.00.2-0.6-1.0
Time in closed arm before self-admin0.81.01.61.0-0.90.9-1.01.0-1.20.9-1.2-1.1
Time in closed arm after self-admin0.20.20.60.5-0.50.5-0.30.50.10.0-0.2-0.8
Time in open arm before self-admin2.12.34.2-1.41.4-1.41.6-1.62.1-1.41.31.3
Time in open arm after self-admin0.20.20.4-0.60.6-0.60.5-0.7-0.1-0.1-0.10.5
Bone: periosteal estimation1.94.06.02.4-2.12.1-2.12.1-2.31.8-1.9-0.9
Bone: periosteal perimeter1.62.84.12.0-1.61.6-1.71.7-2.01.5-1.8-0.9
Bone: post-yield work2.94.35.82.4-2.22.2-2.12.4-2.41.5-1.4-1.8
Progressive ratio test 1 active lever presses0.81.03.20.8-0.80.8-1.10.7-0.01.5-1.8-0.1
Progressive ratio test 1 breakpoint0.81.03.00.9-0.80.8-1.10.70.01.5-1.7-0.1
Progressive ratio test 1 inactive lever presses2.63.75.32.2-2.12.1-2.32.1-0.82.3-1.7-0.9
Progressive ratio test 2 active lever presses0.50.61.10.8-0.80.8-1.01.1-0.20.7-0.5-0.7
Progressive ratio test 2 breakpoint0.60.71.40.9-0.90.9-1.01.2-0.30.7-0.5-0.8
Progressive ratio test 2 inactive lever presses2.43.95.52.3-2.22.2-2.32.3-1.32.2-1.4-0.9
Incentive Sensitization - Responses1.21.73.01.4-1.41.4-1.41.7-1.40.8-0.5-1.4
Incentive Sensitization - Breakpoint0.91.22.21.1-1.11.1-1.11.5-1.20.5-0.3-1.3
Sum of active levers in priming session hrs 5-60.10.10.4-0.30.3-0.30.2-0.4-0.60.1-0.10.3
Progressive ratio0.10.20.90.0-0.20.2-0.0-0.2-0.60.3-0.90.1
Food seeking constrained by brief footshock1.21.45.5-0.20.1-0.1-0.2-1.00.21.7-2.31.9
Seeking ratio, punishment vs. effort0.30.41.00.6-0.50.5-0.70.4-0.21.0-0.70.3
Retroperitoneal fat weight3.916.722.6-4.14.2-4.24.4-3.93.9-4.74.52.6
Reaction time number correct0.40.83.5-0.40.6-0.60.5-0.61.2-0.30.81.9
Reaction time mean minus median0.10.20.9-0.0-0.10.1-0.00.00.70.00.90.7
Reaction time mean minus median AUC0.10.10.8-0.00.0-0.00.1-0.00.5-0.20.90.5
Reaction time num false alarms0.00.10.2-0.20.2-0.2-0.10.10.30.10.4-0.3
Reaction time num false alarms AUC0.20.30.7-0.70.7-0.70.3-0.50.8-0.00.50.3
Reaction time trials correct on left0.40.83.5-0.40.6-0.60.5-0.61.2-0.30.81.9
Reaction time trials on left0.40.83.5-0.40.6-0.60.5-0.61.2-0.30.81.9
Reaction time mean0.71.01.91.1-1.11.1-1.11.4-0.60.70.1-1.3
Reaction time mean AUC0.30.40.90.7-0.70.7-0.71.0-0.10.20.6-0.9
Median of all reaction times0.81.22.81.1-1.11.1-1.11.4-0.70.6-0.0-1.7
Reaction time omissions0.10.10.1-0.40.4-0.40.0-0.20.40.3-0.10.1
Reaction time false alarm rate0.10.10.4-0.40.4-0.40.0-0.10.10.2-0.0-0.6
Reaction time premature initiation rate0.00.10.20.2-0.30.3-0.00.10.1-0.10.40.2
Reaction time premature initiations0.20.31.1-0.10.1-0.10.3-0.20.7-0.50.91.1
Std. dev. reaction times0.30.51.00.8-0.90.9-0.81.0-0.40.50.4-0.5
Reaction time trials completed0.40.83.5-0.40.6-0.60.5-0.61.2-0.30.81.9
Reaction time trials AUC0.40.73.4-0.40.5-0.50.5-0.51.1-0.40.91.8
Run reversals in cocaine runway, females0.70.72.00.8-0.80.8-0.70.8-0.70.4-0.6-1.4
Run reversals in cocaine runway, males0.00.00.20.10.0-0.0-0.20.20.50.1-0.0-0.3
Latency to leave start box in cocaine runway0.40.50.90.8-0.80.8-0.80.9-0.50.7-0.2-0.4
Latency to leave start box in cocaine runway, F0.10.10.20.3-0.30.3-0.30.40.00.30.10.1
Latency to leave start box in cocaine runway, M1.31.21.81.1-1.11.1-1.21.3-1.10.9-0.6-1.1
Std. dev. time between licks in bursts0.20.30.7-0.50.5-0.50.1-0.60.30.7-0.90.3
Total sessions with >9 infusions0.80.92.11.0-1.01.0-1.20.9-0.21.4-1.10.0
Short access day 1 total inactive lever presses0.60.81.51.1-1.01.0-1.01.2-0.50.60.1-0.8
Short access day 10 total inactive lever presses0.10.20.30.5-0.40.4-0.40.6-0.10.10.50.0
Short access day 1 total infusions0.10.10.60.1-0.10.1-0.20.10.80.30.20.5
Short access day 10 total infusions0.10.20.8-0.10.1-0.10.1-0.20.90.10.30.8
Short access total infusions0.20.31.8-0.20.2-0.20.1-0.21.30.10.50.8
Short access day 1 locomotion0.30.40.70.8-0.70.7-0.70.70.30.6-0.10.0
Short access day 10 total locomotion0.30.61.50.7-0.70.7-0.80.4-0.11.2-0.51.1
Short access total locomotion0.40.52.30.3-0.20.2-0.5-0.10.71.1-0.41.5
One hour access (0.3 mA shock)3.33.85.72.2-2.22.2-2.32.4-1.72.0-1.2-0.9
Compulsive drug intake1.82.14.11.5-1.41.4-1.41.6-2.01.1-1.3-1.0
One hour access (shock baseline)0.30.50.90.8-0.80.8-0.91.00.30.70.3-0.4
Social response proportion0.91.12.01.1-1.21.2-1.11.4-0.70.60.2-1.2
Social responses3.44.45.42.0-2.22.2-2.22.3-2.01.9-1.6-2.2
Social time3.14.36.52.1-2.32.3-2.21.7-2.02.6-2.2-0.5
Soleus weight0.00.10.20.3-0.10.1-0.20.1-0.50.1-0.30.4
Bone: stiffness2.33.75.22.3-2.12.1-2.22.2-1.71.8-1.4-1.1
Tibialis anterior weight0.82.74.7-1.41.9-1.91.9-1.70.6-2.21.31.5
Time to tail flick, vehicle, before self-admin0.30.30.60.6-0.50.5-0.60.4-0.60.8-0.80.3
Time to tail flick, vehicle, after self-admin0.30.30.80.6-0.60.6-0.50.9-0.40.10.9-0.3
Time to tail flick, test, before self-admin0.70.72.7-0.70.7-0.70.4-0.91.10.3-0.41.6
Time to tail flick, test, after self-admin0.10.10.3-0.30.3-0.30.3-0.3-0.0-0.40.1-0.6
Delta time to tail flick, vehicle, before/after SA0.60.63.5-0.30.3-0.30.30.10.9-0.81.90.2
Delta time to tail flick, test, before/after SA0.70.73.10.7-0.70.7-0.40.7-1.2-0.0-0.3-1.8
Tibia length3.69.912.73.5-3.53.5-3.23.2-3.62.6-2.8-2.0
Ambulatory time before self-admin1.11.63.71.0-1.01.0-1.30.8-1.41.9-1.9-0.0
Ambulatory time after self-admin0.40.41.6-0.10.2-0.2-0.1-0.5-1.10.8-1.30.4
Bone: tissue strength0.50.53.40.3-0.20.2-0.3-0.20.40.9-0.51.8
Total heroin consumption0.10.10.2-0.20.3-0.30.1-0.2-0.50.0-0.3-0.1
Bone: trabecular number0.20.30.5-0.50.4-0.40.4-0.50.7-0.20.60.6
Bone: trabecular spacing0.00.00.10.1-0.00.00.1-0.0-0.0-0.1-0.40.1
Bone: trabecular thickness0.00.00.00.0-0.00.0-0.10.10.00.20.1-0.1
Bone: trabecular tissue density0.50.71.7-0.90.8-0.81.0-0.80.4-1.31.0-0.2
Water consumed over 24 hours0.70.91.61.1-1.11.1-1.10.8-0.61.3-1.10.2
Number of responses in last shaping day0.20.20.70.3-0.30.3-0.20.30.70.10.90.0