Hub : Genes

Emid1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC alternative TSS NM_001401620.1 0.05 0.04 9.6e-03 0.02 0.01 0.01 0.01 5.3e-02 7.5e-02 1.5e-01 1.5e-01
2 IC alternative TSS XM_008770369.4 0.05 0.04 9.5e-03 0.02 0.01 0 0.01 5.2e-02 7.2e-02 3.2e-01 1.2e-01
3 PL gene expression Emid1 0.33 0.14 0.0e+00 0.24 0.28 0.29 0.29 7.5e-26 4.0e-31 1.4e-31 2.0e-31
4 Adipose mRNA stability Emid1 0.09 0.08 1.5e-03 0.01 0.02 0.02 0.02 1.1e-02 1.1e-03 2.5e-03 4.6e-03
5 Brain isoform ratio NM_001401622.1 0.02 0.02 9.8e-03 0 0.01 -0 -0 2.7e-01 6.6e-02 6.5e-01 8.1e-01
6 Adipose gene expression Emid1 0.09 0.06 4.9e-08 0.04 0.06 0.05 0.06 5.7e-05 2.5e-07 1.4e-06 1.6e-07
7 IL gene expression Emid1 0.39 0.19 2.5e-04 0.15 0.16 0.16 0.15 2.1e-04 1.4e-04 1.1e-04 1.7e-04
8 OFC mRNA stability Emid1 0.45 0.2 1.5e-03 0.11 0.07 0.04 0.07 1.6e-03 8.5e-03 3.1e-02 7.7e-03
9 Brain alternative TSS XM_008770369.4 0.07 0.05 7.8e-05 0.01 0.03 0.03 0.02 5.5e-02 4.2e-04 1.1e-03 3.1e-03
10 IC gene expression Emid1 0.42 0.15 2.0e-12 0.28 0.26 0.27 0.29 2.6e-12 1.5e-11 1.1e-11 1.3e-12
11 NAcc mRNA stability Emid1 0.06 0.07 3.1e-03 0.01 0.01 0.01 0.01 2.1e-03 3.2e-02 2.9e-02 8.5e-03
12 Brain alternative TSS NM_001401620.1 0.07 0.05 7.6e-05 0.01 0.03 0.03 0.02 5.6e-02 4.3e-04 1.3e-03 3.5e-03
13 pVTA gene expression Emid1 0.12 0.07 9.3e-06 0.07 0.07 0.06 0.07 1.7e-06 2.9e-06 1.5e-05 4.1e-06
14 Brain alternative TSS XM_008770369.4 0.07 0.05 8.3e-05 0.01 0.03 0.03 0.02 5.1e-02 4.5e-04 8.5e-04 2.5e-03
15 BLA gene expression Emid1 0.4 0.17 4.0e-12 0.2 0.22 0.21 0.21 5.6e-11 6.1e-12 3.7e-11 1.7e-11
16 Brain alternative TSS NM_001401620.1 0.07 0.05 8.7e-05 0.01 0.03 0.03 0.02 5.3e-02 5.0e-04 8.0e-04 3.0e-03
17 NAcc gene expression Emid1 0.28 0.1 0.0e+00 0.18 0.2 0.19 0.19 1.4e-26 9.2e-29 1.2e-28 1.1e-28
18 Brain gene expression Emid1 0.3 0.13 0.0e+00 0.24 0.18 0.24 0.22 9.9e-23 8.6e-17 3.8e-22 5.6e-20
19 IC mRNA stability Emid1 0.19 0.11 8.2e-03 0.02 0.05 0.01 0.04 4.3e-02 3.5e-03 7.3e-02 7.8e-03
20 Brain mRNA stability Emid1 0.12 0.08 2.5e-04 0.06 0.02 0.04 0.05 7.7e-06 2.2e-03 3.0e-04 2.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.20.31.30.6-0.60.0-0.20.2-0.2-0.2-0.1-0.7-0.3-0.30.7-0.3-0.8-0.30.8-0.4-0.4-0.7-1.1
Area under the delay curve2.22.64.8-2.22.2-1.91.9-2.0-1.6-1.6-1.51.6-1.6-1.6-1.6-1.61.6-1.6-1.6-1.2-1.5-0.20.3
BMI with tail0.00.20.6-0.30.30.1-0.0-0.10.30.30.20.60.20.2-0.60.20.60.1-0.60.40.30.60.8
BMI without tail0.41.32.3-1.01.0-1.31.5-1.2-1.3-1.3-1.30.4-1.5-1.5-0.4-1.50.3-1.2-0.3-1.4-1.1-0.9-0.6
Body weight1.04.36.9-2.52.5-2.52.6-2.5-2.2-2.2-2.21.7-2.2-2.2-1.7-2.21.7-2.3-1.7-1.8-2.0-0.70.2
Weight adjusted by age0.60.91.9-0.80.8-1.01.3-1.0-1.1-1.2-1.40.1-1.2-1.3-0.1-1.20.0-1.1-0.0-1.3-0.5-1.1-0.8
Bone surface0.10.30.8-0.30.3-0.60.3-0.7-0.7-0.6-0.50.2-0.6-0.6-0.2-0.60.2-0.8-0.2-0.4-0.9-0.3-0.5
Bone volume0.20.30.8-0.20.2-0.60.3-0.6-0.7-0.6-0.50.0-0.6-0.6-0.0-0.60.0-0.90.0-0.5-0.9-0.4-0.7
Breakpoint value in progressive ratio session0.40.50.8-0.90.9-0.80.8-0.8-0.7-0.6-0.60.7-0.7-0.7-0.7-0.80.7-0.6-0.7-0.5-0.7-0.10.1
Number of licking bursts1.62.64.0-1.81.8-2.01.9-2.0-1.9-1.8-1.71.2-1.7-1.7-1.2-1.71.2-1.9-1.2-1.4-1.8-0.7-0.0
Context. condit. distance diff. score2.73.35.42.3-2.32.2-2.12.21.91.81.8-1.81.81.81.71.8-1.71.81.71.31.80.3-0.3
Locomotion velocity, session 11.71.94.6-0.30.30.9-1.00.51.31.41.51.31.51.5-1.31.51.41.2-1.41.91.12.22.0
Locomotion distance, session 10.50.61.61.1-1.10.4-0.40.70.10.10.1-1.30.00.01.30.1-1.30.21.3-0.30.0-0.8-1.2
Locomotion velocity, session 21.41.64.2-0.10.10.9-1.20.41.21.41.51.11.41.4-1.11.51.21.0-1.21.91.02.01.8
Locomotion distance, session 21.82.44.41.7-1.71.9-2.11.81.81.81.8-0.91.81.80.91.9-0.81.60.81.71.61.00.3
Locomotion velocity, session 31.72.04.32.1-2.11.5-1.61.71.11.11.1-1.81.11.11.81.1-1.81.01.80.60.9-0.3-0.8
Locomotion distance, session 30.10.10.50.1-0.1-0.2-0.2-0.3-0.4-0.2-0.1-0.1-0.1-0.10.1-0.1-0.1-0.70.10.0-0.7-0.1-0.4
Stereotopy head waving bouts, day 30.60.71.51.2-1.20.9-0.91.00.60.60.6-1.10.60.61.10.5-1.10.61.10.20.6-0.3-0.6
Stereotopy head waving duration, day 31.61.93.01.6-1.61.7-1.51.71.61.51.4-1.21.41.41.21.4-1.11.71.11.01.60.3-0.0
Locomotion velocity, session 70.10.10.2-0.40.4-0.20.1-0.4-0.2-0.2-0.20.4-0.1-0.1-0.4-0.00.4-0.4-0.40.1-0.20.20.2
Locomotion distance, session 70.50.61.10.6-0.61.0-1.00.71.01.01.0-0.11.01.00.11.0-0.10.60.11.00.90.80.6
Stereotopy head waving bouts, day 70.00.00.10.1-0.1-0.10.20.1-0.1-0.1-0.1-0.20.00.00.2-0.1-0.20.10.2-0.2-0.0-0.2-0.1
Stereotopy head waving duration, day 70.20.20.50.2-0.2-0.30.3-0.1-0.4-0.4-0.4-0.4-0.3-0.30.4-0.4-0.5-0.30.5-0.6-0.5-0.7-0.7
Locomotion velocity, session 82.12.54.41.3-1.31.9-2.11.61.92.02.0-0.32.02.00.32.1-0.31.70.22.01.71.50.8
Locomotion distance, session 85.88.412.93.6-3.63.6-3.53.63.23.13.0-2.63.03.02.63.0-2.53.12.52.33.00.8-0.3
Degree of sensitization distance2.22.34.51.1-1.11.9-1.61.62.01.91.8-0.41.81.80.41.8-0.41.90.41.62.11.21.0
Degree of sensitization stereotypy0.10.20.4-0.40.4-0.50.6-0.4-0.5-0.5-0.50.2-0.3-0.3-0.2-0.40.2-0.3-0.2-0.5-0.4-0.3-0.0
Conditioned locomotion0.81.02.71.4-1.40.6-0.60.90.20.20.0-1.60.30.31.70.2-1.70.31.7-0.20.1-1.0-1.2
Cocaine response after cond. corrected1.41.72.7-1.61.6-1.61.7-1.6-1.5-1.4-1.41.1-1.4-1.4-1.1-1.41.0-1.3-1.0-1.1-1.3-0.50.1
Cocaine response after cond. not corrected2.22.64.3-1.71.7-2.02.1-1.8-1.9-1.9-1.90.8-2.0-2.0-0.8-1.90.7-1.7-0.7-1.7-1.7-1.1-0.4
Cocaine response before conditioning0.20.30.80.7-0.70.3-0.20.50.10.10.0-0.9-0.1-0.10.9-0.1-0.90.20.9-0.30.2-0.6-0.7
Saline control response0.70.91.80.9-0.91.1-1.31.01.01.11.1-0.41.31.30.41.3-0.30.90.31.20.90.80.7
Bone: connectivity density0.20.20.90.7-0.70.2-0.40.40.10.00.1-0.8-0.0-0.00.80.0-0.80.00.8-0.2-0.1-0.5-0.9
Bone: cortical apparent density0.50.71.1-0.90.9-1.01.0-1.0-0.9-0.9-0.80.7-1.0-1.0-0.7-1.00.6-0.9-0.6-0.7-1.0-0.3-0.1
Bone: cortical area2.03.14.8-1.91.9-2.22.1-2.1-2.1-2.0-2.01.2-2.0-2.0-1.2-2.01.1-2.1-1.1-1.6-2.0-0.9-0.4
Bone: cortical porosity0.10.10.2-0.10.1-0.40.4-0.3-0.4-0.4-0.4-0.1-0.4-0.40.1-0.4-0.1-0.40.1-0.5-0.4-0.4-0.4
Bone: cortical porosity0.10.10.30.4-0.40.1-0.00.30.00.0-0.0-0.6-0.0-0.00.6-0.0-0.60.10.6-0.20.1-0.4-0.5
Bone: cortical thickness2.03.45.7-1.31.3-2.22.1-2.0-2.4-2.3-2.30.4-2.3-2.3-0.4-2.20.3-2.4-0.3-2.1-2.3-1.6-1.2
Bone: cortical thickness0.81.02.71.2-1.20.2-0.20.6-0.2-0.3-0.3-1.6-0.3-0.31.6-0.3-1.6-0.11.6-0.8-0.1-1.4-1.5
Bone: cortical tissue density0.50.71.1-1.01.0-1.01.0-1.0-0.9-0.9-0.80.8-0.9-0.9-0.8-0.90.7-0.9-0.7-0.6-0.9-0.2-0.0
Condit. Reinf. active minus inactive responses0.91.12.7-0.90.90.1-0.3-0.50.40.50.61.60.60.6-1.60.61.60.0-1.61.10.31.61.6
Condit. Reinf. active-inactive response ratio3.23.48.0-0.30.31.4-1.40.72.02.02.01.62.02.0-1.62.01.71.6-1.72.51.92.82.7
Condit. Reinf. active responses0.30.41.1-0.50.50.0-0.3-0.40.20.30.41.00.40.4-1.00.41.0-0.2-1.00.80.11.11.1
Condit. Reinf. inactive responses0.70.91.8-0.00.0-0.90.6-0.7-1.2-1.1-1.1-0.5-1.1-1.10.5-1.1-0.5-1.40.5-1.1-1.3-1.2-1.1
Incentive salience index mean0.60.72.0-1.01.0-0.40.2-0.8-0.2-0.10.01.4-0.0-0.0-1.40.01.4-0.5-1.40.5-0.31.01.0
Condit. Reinf. lever presses0.20.20.7-0.30.3-0.50.4-0.6-0.6-0.6-0.50.2-0.6-0.6-0.2-0.60.2-0.8-0.2-0.4-0.7-0.3-0.4
Condit. Reinf. active minus inactive responses0.40.50.90.9-0.90.9-0.90.80.80.90.9-0.50.80.80.50.8-0.50.80.50.70.60.4-0.2
Condit. Reinf. active-inactive response ratio0.10.10.20.1-0.10.4-0.40.20.40.50.50.10.40.4-0.10.40.10.3-0.10.50.30.50.3
Condit. Reinf. active responses0.60.91.41.0-1.01.1-1.21.11.11.21.2-0.51.11.10.51.1-0.41.10.41.00.80.6-0.1
Condit. Reinf. inactive responses0.81.01.71.0-1.01.2-1.21.11.21.21.2-0.41.31.30.41.3-0.41.30.41.11.00.70.2
Condit. Reinf. lever presses0.40.51.11.0-1.00.7-0.90.80.60.60.6-0.80.60.60.80.6-0.80.60.80.40.4-0.0-0.7
Condit. Reinf. lever reinforcers received0.50.71.20.9-0.91.0-1.10.90.91.01.1-0.41.01.00.41.0-0.40.90.40.90.70.6-0.2
Conditioned reinforcement - actives0.20.30.7-0.80.8-0.40.7-0.6-0.4-0.5-0.60.5-0.8-0.8-0.5-0.80.4-0.4-0.4-0.50.1-0.20.1
Conditioned reinforcement - inactives0.50.71.3-1.21.2-0.90.9-1.0-0.8-0.7-0.61.0-0.6-0.6-1.0-0.61.0-0.7-1.0-0.3-0.80.20.7
Conditioned locomotion0.81.11.8-1.31.3-1.01.4-1.2-0.9-1.1-1.30.6-1.3-1.3-0.6-1.30.6-1.2-0.5-1.1-0.1-0.7-0.3
Patch foraging indifference point 0 sec1.22.33.6-1.81.8-1.91.9-1.8-1.7-1.7-1.61.1-1.6-1.6-1.1-1.71.1-1.7-1.1-1.4-1.5-0.6-0.0
Patch foraging indifference point AUC0.00.10.4-0.30.3-0.10.0-0.20.00.10.00.40.10.1-0.40.20.4-0.1-0.40.20.10.30.6
Delay disc. indifference point, 0s delay1.31.42.3-1.21.2-1.41.5-1.3-1.3-1.3-1.30.6-1.5-1.5-0.6-1.50.6-1.2-0.6-1.3-1.2-0.8-0.5
Delay disc. indifference point, 16s delay1.41.53.7-1.91.9-1.01.1-1.3-0.7-0.6-0.61.9-0.7-0.7-1.9-0.71.9-0.6-1.9-0.1-0.50.81.2
Delay disc. indifference point, 2s delay2.42.74.3-1.21.2-1.92.0-1.6-2.0-2.0-2.00.2-2.0-2.1-0.2-2.10.1-1.8-0.1-2.0-1.9-1.6-1.3
Delay disc. indifference point, 24s delay0.70.81.7-1.31.3-0.80.7-1.0-0.6-0.5-0.31.3-0.5-0.5-1.3-0.51.3-0.6-1.3-0.0-0.60.60.7
Delay disc. indifference point, 4s delay2.93.04.9-1.91.9-2.12.2-2.0-2.1-2.0-1.91.0-2.0-2.0-1.0-2.00.9-1.9-0.9-1.8-1.9-1.1-0.6
Delay disc. indifference point, 8s delay0.60.71.7-1.31.3-0.90.9-1.0-0.7-0.7-0.61.1-0.7-0.7-1.1-0.61.1-0.7-1.1-0.4-0.60.20.5
Indifference point function ln k0.20.31.10.4-0.4-0.30.1-0.1-0.5-0.4-0.4-0.6-0.5-0.50.6-0.5-0.6-0.60.6-0.6-0.6-0.8-1.1
Indifference point function log k0.20.31.10.4-0.4-0.30.1-0.1-0.5-0.4-0.4-0.6-0.5-0.50.6-0.5-0.6-0.60.6-0.6-0.6-0.8-1.1
Patch foraging total patch changes 0 sec1.12.13.3-1.81.8-1.81.8-1.8-1.6-1.6-1.51.2-1.5-1.5-1.2-1.51.2-1.7-1.2-1.2-1.4-0.40.2
Patch foraging total patch changes 12 sec0.91.12.0-1.31.3-1.31.4-1.3-1.2-1.2-1.30.8-1.1-1.1-0.8-1.10.7-1.2-0.7-1.0-0.9-0.50.3
Patch foraging total patch changes 18 sec1.01.53.9-1.81.8-0.80.8-1.2-0.4-0.3-0.32.0-0.2-0.2-2.0-0.22.0-0.5-2.00.4-0.21.21.7
Patch foraging total patch changes 24 sec0.91.52.70.9-0.91.5-1.31.41.51.41.3-0.41.51.50.41.5-0.41.60.41.31.61.00.9
Patch foraging total patch changes 6 sec1.01.62.7-1.51.5-1.61.4-1.7-1.4-1.3-1.21.3-1.0-1.0-1.3-1.11.2-1.6-1.2-0.8-1.4-0.10.3
Patch foraging time to switch 0 sec0.10.30.60.6-0.60.6-0.40.70.40.40.3-0.70.30.30.70.3-0.70.70.70.10.5-0.2-0.4
Patch foraging water rate 0 sec0.71.42.7-1.61.6-1.21.0-1.5-0.9-0.8-0.71.6-0.8-0.8-1.6-0.71.6-1.2-1.6-0.2-0.90.51.4
Patch foraging water rate 12 sec0.00.00.1-0.00.0-0.0-0.1-0.2-0.0-0.00.00.20.00.1-0.20.10.2-0.3-0.20.1-0.10.20.2
Patch foraging water rate 18 sec0.71.23.40.3-0.3-0.60.9-0.1-0.9-1.0-1.1-1.2-1.1-1.11.2-1.1-1.3-0.71.3-1.6-0.7-1.8-1.3
Patch foraging water rate 24 sec0.30.41.4-0.30.30.4-0.30.10.60.60.60.70.50.5-0.70.60.70.4-0.70.80.71.01.2
Patch foraging water rate 6 sec0.30.50.8-0.60.6-0.80.8-0.8-0.9-0.9-0.90.2-0.9-0.9-0.2-0.80.2-0.9-0.2-0.8-0.7-0.6-0.2
Seeking ratio, delayed vs. immediate footshock0.00.00.4-0.20.20.20.10.30.30.20.2-0.00.00.0-0.0-0.00.00.6-0.00.00.30.10.1
Distance traveled before self-admin1.01.32.5-0.30.3-1.11.2-0.8-1.3-1.3-1.5-0.5-1.2-1.20.5-1.3-0.5-1.20.5-1.6-1.2-1.5-1.5
Distance traveled after self-admin1.21.43.50.1-0.1-0.91.1-0.5-1.2-1.3-1.3-1.0-1.3-1.31.0-1.3-1.0-1.11.0-1.7-1.1-1.9-1.8
Extensor digitorum longus weight2.610.115.9-3.53.5-4.03.7-3.9-3.8-3.6-3.52.3-3.4-3.4-2.3-3.42.2-3.8-2.2-2.8-3.6-1.4-0.5
Bone: elastic displacement0.40.51.40.8-0.80.20.00.5-0.1-0.2-0.2-1.2-0.2-0.21.2-0.2-1.20.11.2-0.60.0-1.0-1.0
Bone: elastic work1.01.33.0-0.10.1-0.91.2-0.5-1.2-1.3-1.3-0.8-1.4-1.40.8-1.4-0.8-0.90.9-1.7-1.0-1.7-1.5
Bone: endosteal estimation0.00.10.3-0.50.5-0.40.5-0.3-0.3-0.3-0.30.2-0.4-0.4-0.2-0.40.2-0.1-0.2-0.4-0.2-0.20.0
Bone: endosteal perimeter0.40.81.7-1.31.3-1.01.1-1.0-0.8-0.8-0.81.0-0.7-0.7-1.0-0.71.0-0.7-1.0-0.5-0.70.10.5
Epididymis fat weight0.31.22.5-0.80.8-1.41.1-1.3-1.5-1.4-1.40.3-1.2-1.2-0.3-1.20.3-1.6-0.3-1.1-1.5-0.9-0.5
Delta time in closed arm before/after self-admin6.05.69.13.0-3.02.8-2.43.02.52.32.0-2.52.22.32.52.2-2.42.62.41.32.70.1-0.7
Delta time in open arm before/after self-admin5.05.09.5-3.13.1-2.52.5-2.7-2.1-2.0-2.12.5-2.1-2.1-2.5-2.02.5-2.1-2.5-1.2-1.90.11.1
Diff in mean of infusions in LGA sessions0.00.00.10.2-0.20.2-0.00.20.10.1-0.0-0.30.10.10.30.0-0.30.20.3-0.10.1-0.2-0.1
Delay discount exponential model param2.22.54.62.1-2.11.8-1.91.91.61.51.4-1.61.61.61.61.6-1.51.61.51.11.50.3-0.3
Extinction: sum of active levers before priming0.20.20.6-0.30.30.1-0.3-0.10.30.30.30.60.40.4-0.60.40.60.2-0.60.70.20.80.6
Active lever presses in extinction session 60.20.20.70.1-0.1-0.10.30.1-0.3-0.4-0.5-0.6-0.4-0.30.6-0.4-0.6-0.10.6-0.6-0.1-0.8-0.8
Bone: final force0.20.30.5-0.50.5-0.60.6-0.6-0.6-0.6-0.60.3-0.7-0.7-0.3-0.70.3-0.7-0.3-0.5-0.6-0.3-0.3
Bone: final moment0.30.60.9-0.70.7-0.90.8-0.8-0.9-0.9-0.90.3-1.0-1.0-0.3-0.90.3-1.0-0.3-0.8-0.8-0.5-0.5
Food consumed during 24 hour testing period1.11.54.1-1.61.6-0.80.5-1.3-0.4-0.2-0.12.0-0.3-0.3-2.0-0.22.0-0.7-2.00.4-0.61.31.4
Glucose12.920.358.6-5.95.9-2.31.8-4.0-0.6-0.10.17.60.10.1-7.60.17.6-1.4-7.72.4-0.75.46.6
Heart weight0.61.02.9-0.30.30.5-0.80.10.80.91.11.10.90.9-1.10.91.20.4-1.21.40.51.71.4
Delay discount hyperbolic model param2.42.64.52.1-2.11.9-2.02.01.71.71.6-1.41.71.71.41.7-1.41.71.41.31.60.5-0.1
Intermittent access intake day 1-15 change0.30.72.0-1.01.0-0.50.3-0.9-0.2-0.2-0.21.4-0.2-0.2-1.4-0.21.4-0.5-1.40.50.01.01.1
Intermittent access intake escalation0.30.61.6-0.90.9-0.40.2-0.8-0.2-0.1-0.11.3-0.1-0.1-1.2-0.11.3-0.5-1.30.5-0.10.91.0
Intermittent access intake escalation 20.10.10.4-0.50.5-0.20.1-0.4-0.1-0.0-0.00.60.00.0-0.6-0.00.6-0.4-0.60.30.00.50.5
Intermitt. access day 1 inactive lever presses0.10.30.70.5-0.50.7-0.50.50.80.80.90.00.70.7-0.00.70.00.8-0.00.60.70.60.7
Intermitt. access day 15 inactive lever presses0.81.74.6-1.51.5-0.90.3-1.1-0.6-0.3-0.12.10.00.0-2.10.12.1-0.5-2.10.8-1.01.62.0
Intermitt. access escalation Index0.71.03.0-0.10.10.6-1.00.30.90.90.91.01.11.1-1.01.11.00.6-1.01.50.81.61.7
Intermittent access day 1 total infusions0.60.91.9-0.90.9-0.91.3-0.7-1.1-1.1-1.2-0.1-1.2-1.30.1-1.3-0.2-0.80.2-1.4-0.7-1.2-0.8
Intermittent access day 15 total infusions1.31.93.5-1.91.9-1.51.6-1.7-1.4-1.4-1.51.3-1.5-1.5-1.3-1.51.2-1.5-1.2-0.9-1.0-0.20.3
Intermittent access terminal intake (last 3 days)1.01.32.2-1.41.4-1.21.5-1.3-1.2-1.3-1.40.8-1.4-1.4-0.8-1.40.8-1.2-0.8-1.0-0.7-0.4-0.0
Intermittent access total infusions1.31.52.5-1.51.5-1.41.6-1.3-1.3-1.4-1.50.7-1.5-1.5-0.7-1.50.6-1.3-0.6-1.2-1.0-0.7-0.3
Intermittent access day 1 locomotion0.30.41.1-0.10.1-0.10.6-0.0-0.3-0.5-0.6-0.7-0.6-0.60.7-0.6-0.7-0.20.7-0.90.3-1.0-1.0
Intermittent access day 15 total locomotion0.61.12.0-1.41.4-1.11.3-1.2-0.9-1.0-1.11.0-1.1-1.2-1.0-1.21.0-0.9-1.0-0.8-0.6-0.20.2
Intermittent access total locomotion0.91.12.1-1.41.4-1.21.3-1.2-1.1-1.2-1.20.8-1.2-1.2-0.8-1.20.8-1.1-0.8-0.9-0.8-0.4-0.1
Intermittent access standard deviation0.20.41.00.6-0.60.6-0.30.60.50.30.2-1.00.20.21.00.1-1.00.21.0-0.20.9-0.6-0.8
Left kidney weight0.21.12.6-0.30.3-1.11.4-0.6-1.2-1.2-1.2-0.5-1.2-1.20.5-1.2-0.5-0.90.5-1.6-1.0-1.5-1.2
Right kidney weight0.62.87.10.2-0.2-1.21.4-0.5-1.6-1.7-1.7-1.6-1.8-1.81.6-1.8-1.7-1.41.7-2.4-1.5-2.7-2.4
Cocaine induced anxiety1.52.13.5-1.81.8-1.61.4-1.9-1.5-1.3-1.21.6-1.5-1.5-1.6-1.41.5-1.7-1.5-0.7-1.50.10.3
Post-drug Anxiety1.31.42.4-1.51.5-1.20.8-1.5-1.1-0.9-0.81.5-0.9-0.9-1.5-0.81.5-1.3-1.5-0.1-1.20.50.7
Baseline Anxiety0.30.30.80.3-0.30.5-0.80.50.60.60.60.10.90.9-0.10.80.10.8-0.10.80.50.60.6
Tail length2.59.714.7-3.03.0-3.83.8-3.6-3.8-3.7-3.51.5-3.7-3.7-1.5-3.61.3-3.7-1.3-3.3-3.7-2.1-1.3
Length with tail2.19.314.6-3.13.1-3.83.7-3.6-3.7-3.7-3.61.6-3.5-3.5-1.6-3.41.5-3.7-1.5-3.1-3.5-1.9-0.9
Length without tail0.20.51.0-0.70.7-1.00.8-1.0-0.9-0.9-0.80.5-0.7-0.7-0.5-0.70.5-1.0-0.5-0.6-0.9-0.3-0.1
Times rat made contact with spout1.51.84.7-0.30.30.9-1.10.31.31.41.51.41.41.4-1.41.51.40.9-1.41.91.12.21.9
Lifetime Intake1.41.72.9-1.51.5-1.41.7-1.3-1.4-1.5-1.60.5-1.7-1.7-0.5-1.70.4-1.3-0.4-1.5-1.0-1.0-0.6
Liver weight, left0.50.92.60.9-0.9-0.10.20.4-0.4-0.5-0.4-1.4-0.5-0.51.4-0.5-1.5-0.21.5-1.0-0.4-1.5-1.6
Liver weight, right0.61.12.91.4-1.40.7-0.51.10.40.30.2-1.70.10.11.70.1-1.70.61.7-0.40.4-1.1-1.3
Locomotor activity0.61.02.5-1.41.4-0.50.8-0.8-0.1-0.1-0.11.6-0.1-0.1-1.6-0.21.6-0.1-1.60.20.00.91.6
Locomotor testing distance0.71.22.3-0.80.8-1.31.5-1.0-1.3-1.4-1.40.0-1.3-1.3-0.0-1.3-0.0-1.10.0-1.5-1.1-1.2-0.5
Locomotor testing rearing1.02.03.2-1.71.7-1.81.7-1.8-1.6-1.5-1.41.4-1.4-1.4-1.4-1.41.3-1.5-1.3-1.1-1.5-0.30.3
Locomotion in novel chamber1.72.24.82.0-2.01.4-1.21.71.00.90.7-2.20.90.92.21.1-2.21.12.20.11.2-0.9-1.2
Locomotion in novel chamber post-restriction2.43.96.61.9-1.92.2-2.52.32.12.32.5-0.62.52.50.62.6-0.52.50.52.41.41.70.8
Fecal boli incidents, locomotor time 10.10.20.40.4-0.40.6-0.60.40.60.60.7-0.00.50.50.00.40.00.5-0.00.50.50.40.4
Change in fecal boli incidents, locomotor task0.60.61.8-0.50.50.3-0.5-0.00.60.70.81.00.70.7-1.00.71.10.4-1.11.10.41.31.1
Time >=10cm from walls, locomotor time 10.10.10.3-0.00.00.1-0.20.10.20.20.20.30.30.4-0.30.40.30.3-0.30.30.30.40.5
Bouts of movement, locomotor time 10.60.71.9-0.80.8-0.1-0.1-0.40.20.30.31.40.40.3-1.40.41.40.1-1.40.80.21.31.3
Total resting periods, locomotor time 10.80.92.6-0.40.40.4-0.60.10.80.80.81.20.80.8-1.20.91.20.7-1.21.30.71.61.4
Rest time, locomotor task time 10.20.30.9-0.10.10.3-0.50.00.50.50.60.60.40.3-0.60.40.70.2-0.70.80.20.90.5
Distance moved, locomotor task time 10.50.71.7-0.60.6-1.01.2-0.7-1.0-1.1-1.2-0.2-0.9-0.90.2-0.8-0.2-0.90.2-1.3-0.8-1.2-0.5
Vertical activity count, locomotor time 10.10.30.8-0.50.5-0.60.9-0.5-0.6-0.7-0.7-0.1-0.6-0.60.1-0.5-0.1-0.50.1-0.9-0.3-0.7-0.2
Time >=10cm from walls, locomotor time 20.10.20.8-0.00.00.4-0.10.40.60.50.40.10.30.3-0.10.30.20.9-0.20.30.90.30.6
Bouts of movement, locomotor time 20.00.00.0-0.10.10.1-0.10.10.00.00.1-0.1-0.1-0.10.1-0.2-0.10.00.10.10.1-0.0-0.1
Total resting periods, locomotor time 20.00.00.1-0.20.20.1-0.20.00.10.10.20.10.00.0-0.1-0.00.10.0-0.10.30.10.30.1
Rest time, locomotor task time 20.20.20.60.4-0.40.5-0.70.40.50.60.60.00.60.6-0.00.50.00.4-0.00.70.30.60.3
Distance moved, locomotor task time 20.00.00.10.1-0.10.20.10.20.20.10.1-0.2-0.0-0.00.20.2-0.20.20.2-0.10.4-0.10.1
Vertical activity count, locomotor time 20.00.10.2-0.10.1-0.10.4-0.1-0.1-0.2-0.2-0.1-0.4-0.40.1-0.3-0.1-0.10.1-0.50.1-0.4-0.1
Light reinforcement 10.40.91.8-0.30.3-1.00.9-0.7-1.2-1.2-1.2-0.4-1.1-1.10.5-1.2-0.5-1.10.5-1.2-1.1-1.3-1.4
Light reinforcement 20.71.02.1-0.60.6-1.01.2-0.6-1.2-1.3-1.4-0.4-1.2-1.20.4-1.2-0.5-0.90.5-1.4-0.8-1.4-1.1
Bone: marrow area0.00.10.2-0.40.4-0.20.4-0.2-0.2-0.2-0.20.1-0.3-0.3-0.1-0.30.1-0.0-0.1-0.3-0.1-0.10.0
Bone: maximum diameter2.54.69.0-3.03.0-2.32.1-2.7-1.8-1.6-1.42.9-1.5-1.5-2.9-1.52.9-2.0-2.9-0.6-1.80.81.4
Bone: maximum force0.30.61.1-0.40.4-0.80.8-0.7-0.9-0.9-0.9-0.0-1.0-1.00.0-1.0-0.1-0.90.1-0.9-0.8-0.8-0.8
Bone: maximum moment0.50.91.7-0.50.5-1.11.0-0.9-1.2-1.2-1.2-0.0-1.3-1.30.0-1.2-0.1-1.20.1-1.2-1.1-1.0-0.9
Mean time between licks in bursts0.51.23.1-1.01.00.1-0.2-0.40.50.60.71.70.60.6-1.70.61.70.3-1.71.20.41.71.7
Mean num. licks in bursts2.53.86.21.4-1.42.3-2.41.92.52.52.5-0.22.42.40.22.4-0.12.20.12.52.32.01.3
Cd content in liver0.40.41.2-0.80.8-0.40.3-0.6-0.1-0.1-0.01.1-0.1-0.1-1.1-0.01.1-0.2-1.10.3-0.20.70.9
Co content in liver0.40.50.9-0.20.2-0.90.7-0.6-0.9-0.9-0.9-0.1-0.9-0.90.1-0.9-0.1-0.90.2-0.9-1.0-0.8-0.7
Cu content in liver0.10.20.5-0.40.4-0.20.1-0.3-0.1-0.0-0.00.70.10.1-0.70.20.7-0.2-0.70.3-0.10.50.7
Fe content in liver2.22.74.31.6-1.62.1-2.01.92.02.02.0-0.81.91.90.82.1-0.81.90.81.71.91.10.3
K content in liver3.73.66.2-1.01.0-2.22.0-1.7-2.4-2.4-2.3-0.1-2.4-2.40.1-2.5-0.2-2.10.2-2.4-2.4-2.1-1.4
Mg content in liver0.60.61.2-0.40.4-1.00.7-0.7-1.1-1.1-1.0-0.0-0.9-0.80.0-0.9-0.1-0.90.1-0.9-1.1-0.8-0.5
Mn content in liver1.01.12.0-0.10.1-1.00.8-0.7-1.3-1.3-1.3-0.6-1.1-1.10.6-1.2-0.7-1.20.7-1.3-1.3-1.4-1.3
Na content in liver1.51.63.1-1.81.8-1.41.2-1.5-1.1-1.0-0.91.6-0.9-0.9-1.6-1.01.6-1.1-1.6-0.4-1.10.40.6
Rb content in liver2.12.44.1-1.51.5-2.01.8-1.7-2.0-1.9-2.00.7-1.8-1.8-0.7-1.70.7-1.8-0.7-1.6-1.8-1.1-0.6
Se content in liver1.92.34.0-0.70.7-1.71.4-1.4-2.0-2.0-1.9-0.1-1.9-1.90.2-1.9-0.2-1.90.2-1.8-2.0-1.6-1.4
Sr content in liver2.42.14.2-2.02.0-1.51.4-1.7-1.1-1.0-0.92.0-0.9-0.9-2.0-0.92.0-1.2-2.0-0.3-1.10.61.1
Zn content in liver0.50.61.1-0.30.3-0.90.8-0.7-1.0-1.0-1.0-0.1-0.9-0.90.1-0.9-0.1-0.90.1-1.0-1.0-0.9-0.7
Bone: minimum diameter0.10.10.40.1-0.1-0.10.20.0-0.2-0.3-0.3-0.4-0.4-0.40.4-0.4-0.4-0.10.4-0.5-0.1-0.6-0.7
Time in familiar zone, hab. session 10.10.10.20.4-0.40.4-0.40.30.20.20.1-0.50.20.20.50.2-0.50.10.50.10.2-0.2-0.3
Time in novel zone, hab. session 10.60.61.0-0.70.7-1.01.0-0.8-1.0-1.0-0.90.3-1.0-1.0-0.3-1.00.3-0.8-0.3-0.9-0.9-0.7-0.3
Total zone transitions, hab. session 10.00.00.1-0.00.00.0-0.2-0.10.00.10.20.30.20.2-0.30.20.3-0.1-0.30.3-0.10.30.2
Total locomotion distance, hab. session 10.20.20.5-0.30.3-0.60.4-0.5-0.6-0.6-0.60.0-0.6-0.60.0-0.6-0.0-0.70.0-0.5-0.7-0.5-0.4
Locomotion velocity, hab. session 10.00.00.0-0.10.10.0-0.1-0.10.00.10.10.20.10.1-0.20.10.2-0.0-0.20.20.00.20.1
Time in familiar zone, hab. session 21.41.52.71.2-1.21.6-1.21.61.51.41.3-0.91.31.30.91.3-0.91.60.90.91.70.40.2
Time in novel zone, hab. session 22.12.13.8-1.41.4-1.81.4-1.9-1.8-1.6-1.51.1-1.6-1.6-1.1-1.61.0-1.9-1.0-1.1-2.0-0.5-0.2
Total zone transitions, hab. session 20.40.50.9-0.80.8-0.90.6-0.9-0.8-0.7-0.60.8-0.7-0.7-0.8-0.60.7-0.9-0.7-0.3-0.90.00.0
Total locomotion distance, hab. session 20.40.51.1-0.90.9-0.70.4-0.9-0.6-0.5-0.41.0-0.4-0.4-1.0-0.31.0-0.8-1.00.1-0.70.50.4
Locomotion velocity, hab. session 20.50.71.2-1.11.1-0.90.7-1.1-0.8-0.7-0.61.1-0.7-0.7-1.1-0.61.0-1.0-1.0-0.2-0.90.30.3
Novel to familiar place preference ratio0.70.82.3-1.21.2-0.50.5-0.8-0.1-0.1-0.01.5-0.0-0.0-1.5-0.21.5-0.2-1.50.4-0.11.01.3
Novelty place preference0.80.92.5-1.21.2-0.50.5-0.9-0.2-0.1-0.01.6-0.0-0.0-1.6-0.21.6-0.3-1.60.4-0.21.01.3
Time in novel zone, NPP test0.70.82.3-1.21.2-0.50.5-0.8-0.2-0.1-0.11.5-0.0-0.0-1.5-0.21.5-0.3-1.50.3-0.21.01.2
Total zone transitions, NPP test0.40.61.71.0-1.00.4-0.50.60.0-0.0-0.0-1.2-0.1-0.11.20.0-1.20.01.2-0.3-0.1-0.8-1.3
Total locomotion distance, NPP test0.10.10.50.5-0.50.1-0.30.2-0.1-0.1-0.0-0.6-0.1-0.20.6-0.1-0.6-0.20.6-0.1-0.2-0.4-0.7
Locomotion velocity, NPP test0.10.10.40.2-0.2-0.1-0.00.0-0.2-0.2-0.2-0.4-0.3-0.30.4-0.2-0.4-0.30.4-0.2-0.3-0.4-0.6
Intraocular pressure0.40.61.7-0.70.70.0-0.1-0.30.40.50.51.20.40.4-1.20.41.20.2-1.30.80.31.31.3
Delta distance traveled before/after self-admin0.50.50.80.9-0.90.9-0.70.90.80.70.8-0.70.60.60.70.7-0.70.80.70.40.80.00.1
Delta ambulatory time before/after self-admin0.50.71.21.1-1.11.0-0.90.90.90.80.9-0.80.80.80.80.8-0.80.70.80.50.80.1-0.0
Parametrial fat weight2.45.616.0-2.72.7-0.50.3-1.40.40.60.73.90.70.7-3.90.63.90.2-3.92.00.33.44.0
Pavlov. Cond. lever latency0.20.30.8-0.90.9-0.40.5-0.5-0.2-0.2-0.20.9-0.1-0.1-0.9-0.10.9-0.0-0.90.0-0.00.40.7
Pavlov. Cond. magazine entry latency1.72.24.02.0-2.01.9-1.81.81.61.41.4-1.61.31.31.61.3-1.51.31.51.01.40.2-0.6
Pavlov. Cond. change in total contacts0.50.51.0-0.80.8-0.80.5-1.0-0.7-0.6-0.50.8-0.6-0.6-0.8-0.60.8-1.0-0.8-0.2-0.90.20.1
Pavlov. Cond. index score1.51.94.22.0-2.01.6-1.61.61.21.11.1-1.71.01.01.71.0-1.71.01.70.71.0-0.2-1.0
Pavlov. Cond. latency score1.21.53.31.8-1.81.4-1.41.41.00.90.9-1.60.80.81.60.8-1.60.81.60.50.8-0.3-0.9
Pavlov. Cond. lever contacts0.60.82.01.4-1.40.8-0.90.90.50.50.5-1.30.40.41.30.4-1.30.31.30.20.2-0.5-0.9
Pavlov. Cond. magazine entry number2.02.64.7-2.22.2-2.02.1-1.8-1.7-1.6-1.61.6-1.5-1.5-1.6-1.51.5-1.3-1.5-1.3-1.4-0.40.5
Pavlov. Cond. intertrial magazine entries1.11.32.5-0.80.8-1.31.5-0.9-1.4-1.5-1.6-0.1-1.4-1.40.1-1.4-0.2-1.10.2-1.6-1.1-1.4-0.8
Pavlov. Cond. lever-magazine prob. diff.1.82.24.92.2-2.21.7-1.71.71.21.11.1-2.01.01.02.01.0-1.91.01.90.61.0-0.3-1.2
Pavlov. Cond. response bias0.91.12.81.7-1.71.1-1.31.10.70.70.7-1.50.60.61.50.6-1.50.41.50.40.4-0.4-1.0
Pavlov. Cond. lever latency4.25.78.8-2.22.2-2.92.9-2.6-3.0-3.0-3.00.8-2.8-2.8-0.8-2.80.7-2.8-0.7-2.7-2.7-1.9-1.0
Pavlov. Cond. magazine entry latency0.10.10.30.5-0.50.3-0.50.30.20.30.3-0.30.20.20.30.3-0.30.10.30.30.10.1-0.2
Pavlov. Cond. change in total contacts0.30.50.80.4-0.40.8-0.80.70.90.90.90.00.80.8-0.00.90.10.9-0.10.90.80.70.3
Pavlov. Cond. index score1.21.72.81.3-1.31.6-1.71.41.61.61.6-0.61.51.50.51.5-0.51.50.51.51.41.00.3
Pavlov. Cond. latency score1.41.83.11.5-1.51.6-1.81.51.61.61.6-0.81.51.50.81.5-0.81.50.81.41.40.80.1
Pavlov. Cond. lever contacts4.05.58.42.3-2.32.9-2.92.72.92.92.9-1.02.82.81.02.8-0.92.80.92.62.71.70.8
Pavlov. Cond. magazine entry number0.20.30.6-0.30.3-0.50.7-0.4-0.6-0.7-0.7-0.2-0.7-0.70.2-0.7-0.2-0.40.2-0.8-0.4-0.7-0.4
Pavlov. Cond. intertrial magazine entries0.00.00.0-0.10.1-0.1-0.0-0.0-0.10.00.00.10.10.1-0.10.10.1-0.0-0.10.1-0.20.20.1
Pavlov. Cond. lever-magazine prob. diff.1.21.72.91.4-1.41.6-1.71.51.51.51.6-0.71.51.50.71.5-0.71.40.71.41.40.80.1
Pavlov. Cond. response bias2.23.04.91.5-1.52.1-2.11.82.22.22.2-0.52.02.00.52.0-0.42.10.42.01.91.50.8
Time in closed arm before self-admin0.60.81.8-0.50.5-0.91.1-0.8-1.0-1.0-0.9-0.2-1.2-1.20.2-1.2-0.2-1.00.3-1.3-1.0-1.1-0.9
Time in closed arm after self-admin1.71.83.61.9-1.91.4-1.11.61.11.00.9-1.81.01.01.81.0-1.81.11.80.21.1-0.6-0.8
Time in open arm before self-admin0.40.50.90.9-0.90.8-0.90.90.70.60.7-0.70.70.60.70.6-0.70.70.70.60.60.1-0.3
Time in open arm after self-admin0.70.82.2-1.31.3-0.40.4-0.7-0.2-0.1-0.11.5-0.3-0.3-1.5-0.21.5-0.0-1.50.4-0.11.01.1
Bone: periosteal estimation0.71.42.3-1.31.3-1.51.5-1.4-1.4-1.4-1.30.8-1.4-1.4-0.8-1.40.7-1.3-0.7-1.2-1.2-0.6-0.2
Bone: periosteal perimeter1.11.93.0-1.71.7-1.71.7-1.7-1.5-1.4-1.41.3-1.4-1.4-1.3-1.31.2-1.4-1.2-1.1-1.3-0.30.2
Bone: post-yield work0.00.10.2-0.20.2-0.30.2-0.3-0.3-0.3-0.30.2-0.4-0.4-0.2-0.30.2-0.4-0.2-0.2-0.3-0.1-0.1
Progressive ratio test 1 active lever presses0.60.81.4-1.01.0-0.91.2-0.9-0.9-1.0-1.10.4-1.2-1.2-0.4-1.10.4-0.8-0.4-1.0-0.6-0.6-0.3
Progressive ratio test 1 breakpoint0.50.71.2-0.90.9-0.91.1-0.9-0.9-0.9-1.00.5-1.1-1.1-0.5-1.00.4-0.8-0.4-0.8-0.5-0.5-0.3
Progressive ratio test 1 inactive lever presses2.73.96.1-2.52.5-2.42.2-2.4-2.2-2.0-1.82.0-1.9-2.0-2.0-1.92.0-2.0-1.9-1.2-2.3-0.20.4
Progressive ratio test 2 active lever presses0.70.91.5-1.21.2-1.01.1-1.1-0.9-1.0-1.00.8-1.2-1.2-0.8-1.10.8-0.9-0.8-0.7-0.7-0.20.1
Progressive ratio test 2 breakpoint0.60.71.2-1.11.1-0.90.9-0.9-0.8-0.8-0.80.8-1.0-1.0-0.8-0.90.8-0.8-0.8-0.5-0.6-0.10.2
Progressive ratio test 2 inactive lever presses0.71.22.5-1.61.6-1.01.0-1.2-0.8-0.8-0.71.5-0.9-0.9-1.5-0.81.5-0.7-1.5-0.2-0.80.51.0
Incentive Sensitization - Responses0.20.20.6-0.60.6-0.40.3-0.5-0.2-0.2-0.20.8-0.3-0.3-0.8-0.30.8-0.2-0.80.1-0.30.40.6
Incentive Sensitization - Breakpoint0.10.20.5-0.50.5-0.30.3-0.4-0.1-0.1-0.10.7-0.2-0.2-0.7-0.20.7-0.1-0.70.1-0.20.40.6
Sum of active levers in priming session hrs 5-60.30.21.0-0.10.1-0.60.3-0.5-0.6-0.5-0.50.1-0.4-0.4-0.1-0.40.1-0.7-0.1-0.4-1.0-0.3-0.9
Progressive ratio0.10.20.50.1-0.10.10.30.30.1-0.1-0.1-0.6-0.3-0.40.6-0.4-0.60.20.6-0.60.3-0.7-0.7
Food seeking constrained by brief footshock3.94.87.7-1.71.7-2.72.7-2.3-2.8-2.7-2.70.5-2.5-2.5-0.5-2.60.4-2.6-0.3-2.6-2.7-2.0-1.7
Seeking ratio, punishment vs. effort0.71.03.6-0.70.7-1.40.9-1.2-1.5-1.3-1.10.5-0.9-0.9-0.5-1.00.5-1.5-0.5-0.8-1.9-0.5-0.4
Retroperitoneal fat weight0.52.36.8-1.51.5-0.20.0-0.80.40.50.62.50.80.8-2.50.72.50.2-2.51.40.42.32.6
Reaction time number correct0.10.20.5-0.00.00.2-0.40.00.30.40.40.50.40.4-0.50.40.50.2-0.50.60.10.70.4
Reaction time mean minus median1.12.84.71.2-1.22.0-2.01.72.12.12.2-0.12.02.00.12.0-0.02.10.02.12.01.71.5
Reaction time mean minus median AUC0.51.42.11.2-1.21.4-1.41.31.51.41.4-0.61.31.30.51.3-0.51.50.51.21.40.80.8
Reaction time num false alarms0.60.81.6-0.00.0-0.80.6-0.6-1.1-1.1-1.0-0.6-1.1-1.10.6-1.1-0.6-1.30.6-1.2-1.2-1.2-0.9
Reaction time num false alarms AUC0.81.32.80.1-0.1-0.80.7-0.6-1.2-1.3-1.2-1.0-1.3-1.31.0-1.3-1.0-1.41.0-1.5-1.4-1.7-1.4
Reaction time trials correct on left0.10.20.5-0.00.00.2-0.40.00.30.40.40.50.40.4-0.50.40.50.2-0.50.60.10.70.4
Reaction time trials on left0.10.20.50.0-0.00.2-0.50.10.30.40.40.40.40.4-0.40.40.40.2-0.40.70.20.70.4
Reaction time mean0.71.12.10.9-0.91.3-1.11.21.41.31.3-0.31.21.20.31.2-0.31.50.31.11.30.80.8
Reaction time mean AUC0.81.32.41.1-1.11.4-1.21.41.41.41.4-0.71.31.30.71.2-0.61.50.61.01.40.60.6
Median of all reaction times0.40.51.20.6-0.60.9-0.70.91.00.90.9-0.30.80.80.30.8-0.31.10.30.71.00.50.5
Reaction time omissions1.11.62.51.6-1.61.5-1.41.61.41.31.3-1.21.21.21.21.3-1.11.51.10.91.30.2-0.1
Reaction time false alarm rate1.11.63.60.1-0.1-1.00.9-0.6-1.4-1.4-1.3-1.0-1.4-1.41.1-1.4-1.1-1.41.1-1.7-1.4-1.9-1.5
Reaction time premature initiation rate1.72.35.32.3-2.31.4-1.31.71.00.80.8-2.30.80.82.30.8-2.31.02.30.10.9-1.0-1.4
Reaction time premature initiations0.81.43.31.8-1.81.1-1.31.30.80.80.8-1.60.80.81.60.8-1.60.81.60.40.7-0.4-1.0
Std. dev. reaction times1.42.64.41.2-1.21.9-1.81.72.12.02.1-0.21.91.90.21.9-0.12.10.11.92.01.51.5
Reaction time trials completed0.10.20.50.0-0.00.2-0.50.10.30.40.40.40.40.4-0.40.40.40.2-0.40.70.20.70.4
Reaction time trials AUC0.00.10.3-0.10.10.1-0.3-0.10.10.20.30.50.20.2-0.50.20.50.0-0.50.5-0.00.60.3
Run reversals in cocaine runway, females0.90.81.51.1-1.11.1-1.21.11.01.11.2-0.51.21.20.50.9-0.51.00.51.00.60.60.1
Run reversals in cocaine runway, males0.40.40.7-0.70.7-0.70.8-0.8-0.6-0.7-0.70.4-0.8-0.8-0.4-0.60.3-0.8-0.3-0.7-0.3-0.4-0.1
Latency to leave start box in cocaine runway0.40.40.9-0.10.1-0.70.7-0.4-0.8-0.8-0.8-0.4-0.7-0.70.4-0.6-0.4-0.70.4-0.9-0.9-0.9-0.8
Latency to leave start box in cocaine runway, F1.51.72.7-0.80.8-1.61.5-1.3-1.6-1.6-1.60.0-1.5-1.50.0-1.5-0.1-1.60.1-1.6-1.6-1.4-1.5
Latency to leave start box in cocaine runway, M0.40.40.90.7-0.70.7-0.60.90.70.60.6-0.50.60.60.50.8-0.51.00.50.50.60.20.6
Std. dev. time between licks in bursts0.10.20.40.1-0.10.4-0.50.20.50.50.50.20.50.5-0.20.50.30.3-0.30.60.40.60.6
Total sessions with >9 infusions0.70.93.00.6-0.60.30.30.4-0.1-0.3-0.5-1.5-0.6-0.61.5-0.5-1.5-0.11.5-1.10.5-1.6-1.7
Short access day 1 total inactive lever presses3.44.57.3-2.42.4-2.62.7-2.5-2.4-2.4-2.41.3-2.5-2.5-1.3-2.41.2-2.4-1.2-2.1-2.2-1.2-0.4
Short access day 10 total inactive lever presses0.00.10.2-0.30.3-0.30.3-0.4-0.3-0.2-0.10.2-0.1-0.1-0.2-0.10.2-0.4-0.2-0.2-0.4-0.00.1
Short access day 1 total infusions0.70.92.90.5-0.50.10.30.3-0.2-0.4-0.5-1.4-0.7-0.71.4-0.6-1.4-0.21.4-1.10.3-1.6-1.7
Short access day 10 total infusions0.40.51.60.1-0.1-0.20.60.1-0.4-0.5-0.6-0.9-0.8-0.80.9-0.7-0.9-0.10.9-1.1-0.0-1.2-1.2
Short access total infusions1.01.32.8-0.50.5-0.81.3-0.6-1.0-1.2-1.4-0.6-1.5-1.50.7-1.4-0.7-0.90.7-1.7-0.5-1.7-1.6
Short access day 1 locomotion1.41.76.60.9-0.90.20.20.4-0.3-0.5-0.7-2.0-0.8-0.82.0-0.7-2.0-0.42.0-1.50.3-2.1-2.6
Short access day 10 total locomotion0.61.13.70.9-0.90.50.20.60.3-0.1-0.4-1.6-0.3-0.31.6-0.3-1.70.11.7-1.11.2-1.6-1.9
Short access total locomotion1.21.44.61.0-1.00.60.10.70.2-0.1-0.4-1.9-0.4-0.41.9-0.3-1.90.11.9-1.11.0-1.8-2.1
One hour access (0.3 mA shock)1.31.42.5-1.61.6-1.31.5-1.4-1.3-1.3-1.30.9-1.4-1.4-0.9-1.40.9-1.2-0.9-1.1-0.9-0.5-0.1
Compulsive drug intake1.11.32.11.5-1.51.3-1.11.41.21.11.1-1.21.21.21.21.1-1.21.21.20.61.1-0.0-0.4
One hour access (shock baseline)1.11.63.2-1.81.8-1.41.5-1.5-1.2-1.3-1.41.2-1.5-1.5-1.2-1.51.1-1.2-1.1-0.9-0.7-0.30.2
Social response proportion1.21.44.0-1.31.3-0.30.2-0.80.20.30.52.00.30.3-2.00.32.0-0.1-2.00.90.01.71.7
Social responses1.31.64.8-1.61.6-0.60.4-1.1-0.1-0.00.22.20.10.1-2.20.12.2-0.4-2.20.7-0.31.61.8
Social time0.50.61.6-0.20.20.4-0.50.10.70.70.80.90.90.9-0.91.00.90.5-0.91.00.61.31.2
Soleus weight1.33.96.6-1.61.6-2.32.6-1.8-2.4-2.4-2.50.2-2.5-2.5-0.2-2.50.1-2.0-0.1-2.5-2.0-2.0-1.4
Bone: stiffness0.00.00.10.2-0.20.2-0.20.20.20.20.2-0.10.10.10.10.1-0.10.20.10.10.20.0-0.1
Tibialis anterior weight0.82.74.5-2.12.1-1.91.9-2.1-1.7-1.6-1.61.6-1.6-1.5-1.6-1.61.6-1.8-1.6-1.1-1.6-0.20.2
Time to tail flick, vehicle, before self-admin0.10.10.2-0.00.0-0.20.2-0.2-0.3-0.3-0.3-0.2-0.3-0.30.2-0.3-0.2-0.30.2-0.4-0.4-0.4-0.4
Time to tail flick, vehicle, after self-admin0.10.20.40.5-0.50.6-0.50.60.40.50.4-0.50.50.50.50.4-0.40.40.40.30.30.1-0.1
Time to tail flick, test, before self-admin0.20.20.70.0-0.0-0.30.5-0.1-0.4-0.5-0.5-0.5-0.5-0.50.5-0.4-0.5-0.30.5-0.8-0.2-0.8-0.5
Time to tail flick, test, after self-admin2.52.64.4-1.61.6-2.11.9-1.9-2.0-1.9-2.10.9-1.7-1.6-0.9-1.70.9-2.0-0.9-1.6-1.9-0.90.0
Delta time to tail flick, vehicle, before/after SA0.20.20.50.2-0.20.6-0.40.50.60.50.5-0.10.50.50.10.4-0.10.70.10.40.70.30.1
Delta time to tail flick, test, before/after SA0.60.71.5-1.01.0-0.80.5-0.9-0.5-0.4-0.51.2-0.3-0.3-1.2-0.41.2-0.7-1.20.2-0.70.70.9
Tibia length0.61.54.30.4-0.4-0.61.00.1-1.0-1.1-1.3-1.5-1.2-1.21.5-1.1-1.5-0.41.5-1.7-0.7-2.1-2.1
Ambulatory time before self-admin1.62.44.3-0.80.8-1.71.8-1.3-1.9-1.9-2.1-0.3-1.8-1.80.3-1.9-0.3-1.70.3-2.1-1.7-1.9-1.7
Ambulatory time after self-admin0.81.02.40.0-0.0-0.81.0-0.5-1.0-1.1-1.2-0.8-1.0-1.00.8-1.0-0.8-0.90.8-1.5-0.9-1.6-1.3
Bone: tissue strength0.00.00.1-0.30.3-0.10.2-0.10.10.10.10.30.00.0-0.40.00.40.2-0.40.10.20.20.3
Total heroin consumption0.00.00.10.0-0.00.1-0.00.1-0.1-0.0-0.1-0.2-0.0-0.00.2-0.1-0.20.00.2-0.1-0.1-0.1-0.3
Bone: trabecular number0.30.41.40.3-0.3-0.40.3-0.1-0.6-0.6-0.6-0.7-0.7-0.70.7-0.6-0.7-0.50.7-0.8-0.6-1.0-1.2
Bone: trabecular spacing0.70.91.8-1.41.4-0.90.9-1.1-0.7-0.6-0.61.3-0.6-0.6-1.3-0.61.3-0.8-1.3-0.2-0.60.40.8
Bone: trabecular thickness0.91.12.81.5-1.50.8-0.81.10.40.40.3-1.70.40.41.70.3-1.70.51.7-0.20.4-0.9-1.3
Bone: trabecular tissue density1.01.52.70.4-0.41.2-1.30.91.41.51.50.41.51.5-0.41.50.51.2-0.51.61.31.61.6
Water consumed over 24 hours0.71.02.9-1.21.2-0.50.2-1.0-0.10.00.21.7-0.1-0.1-1.70.01.7-0.5-1.70.6-0.21.21.3
Number of responses in last shaping day0.20.20.30.6-0.60.5-0.40.50.40.40.4-0.50.30.30.50.3-0.50.30.50.20.6-0.1-0.4