Hub : Genes

Eif4g3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XM_039109671.2 0.06 0.06 3.2e-05 0.04 0.04 0.04 0.04 2.0e-04 1.0e-04 2.8e-04 8.2e-05
2 Brain alternative TSS XM_017593294.3 0.08 0.08 3.6e-07 0.07 0.07 0.07 0.06 8.1e-07 1.8e-07 8.3e-07 1.1e-06
3 Brain alternative TSS XM_017593294.3 0.05 0.05 6.4e-05 0.04 0.05 0.04 0.04 1.0e-04 3.8e-05 1.0e-04 1.4e-04
4 Brain isoform ratio XM_063287469.1 0.05 0.05 1.1e-04 0.04 0.05 0.04 0.04 5.9e-05 3.9e-05 8.1e-05 7.1e-05
5 Brain alternative TSS XM_039109672.2 0.11 0.1 1.8e-09 0.09 0.1 0.09 0.09 6.0e-09 1.8e-09 9.3e-09 7.4e-09
6 Brain alternative TSS XM_039109672.2 0.08 0.08 4.2e-07 0.07 0.07 0.07 0.06 8.0e-07 5.4e-07 9.6e-07 1.7e-06
7 OFC gene expression Eif4g3 0.16 0.14 3.7e-03 0.09 0.08 0.04 0.09 4.1e-03 5.6e-03 3.2e-02 4.2e-03
8 OFC mRNA stability Eif4g3 0.14 0.13 6.9e-03 0.08 0.04 0.04 0.07 5.1e-03 3.9e-02 4.4e-02 1.2e-02
9 Brain isoform ratio XM_063287465.1 0.03 0.04 1.2e-03 0.03 0.03 0.02 0.03 5.7e-04 1.5e-03 2.3e-03 1.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.00.1-0.40.20.2-0.2-0.2-0.2-0.1-0.1-0.0
Area under the delay curve0.40.40.5-0.70.70.7-0.7-0.7-0.70.60.60.6
BMI with tail0.10.40.60.8-0.7-0.70.70.70.7-0.4-0.4-0.7
BMI without tail1.95.77.62.3-2.2-2.22.22.22.2-2.6-2.6-2.8
Body weight1.56.77.72.8-2.6-2.62.62.62.6-2.4-2.4-2.7
Weight adjusted by age1.82.73.91.3-1.5-1.51.51.51.5-1.9-1.9-2.0
Bone surface0.10.10.3-0.30.20.2-0.2-0.2-0.1-0.5-0.5-0.5
Bone volume0.00.10.2-0.40.30.3-0.3-0.3-0.3-0.3-0.3-0.1
Breakpoint value in progressive ratio session1.41.72.11.4-1.5-1.51.51.51.4-1.0-1.0-0.9
Number of licking bursts0.00.10.10.3-0.2-0.20.20.20.2-0.4-0.4-0.3
Context. condit. distance diff. score0.60.70.90.9-1.0-1.01.01.00.9-0.6-0.6-0.7
Locomotion velocity, session 11.41.52.1-1.31.41.4-1.4-1.4-1.40.70.70.9
Locomotion distance, session 12.63.33.4-1.81.81.8-1.8-1.8-1.81.81.81.7
Locomotion velocity, session 24.55.25.5-2.32.32.3-2.3-2.3-2.32.22.22.2
Locomotion distance, session 21.01.51.8-1.31.41.4-1.3-1.4-1.30.90.90.8
Locomotion velocity, session 31.01.11.3-1.11.11.1-1.1-1.1-1.10.90.90.9
Locomotion distance, session 31.01.11.71.0-0.9-0.90.90.90.9-1.3-1.3-1.2
Stereotopy head waving bouts, day 31.21.42.1-1.41.41.4-1.4-1.4-1.30.70.70.8
Stereotopy head waving duration, day 30.60.70.9-1.00.90.9-0.9-0.9-0.90.50.50.5
Locomotion velocity, session 72.02.22.71.4-1.6-1.61.61.61.6-1.1-1.1-1.4
Locomotion distance, session 70.30.40.50.7-0.7-0.70.70.70.7-0.4-0.4-0.6
Stereotopy head waving bouts, day 70.30.41.00.3-0.3-0.30.30.30.3-1.0-1.0-0.9
Stereotopy head waving duration, day 70.20.20.60.3-0.2-0.20.20.20.3-0.7-0.7-0.7
Locomotion velocity, session 81.01.11.2-0.91.11.1-1.1-1.1-1.11.11.11.0
Locomotion distance, session 80.00.00.0-0.00.00.0-0.0-0.0-0.00.10.1-0.0
Degree of sensitization distance0.70.71.4-0.80.60.6-0.6-0.6-0.61.21.21.1
Degree of sensitization stereotypy1.41.62.01.2-1.2-1.21.21.21.2-1.3-1.3-1.4
Conditioned locomotion1.51.72.6-1.11.21.2-1.2-1.2-1.21.61.61.5
Cocaine response after cond. corrected0.20.31.0-0.20.20.2-0.2-0.2-0.21.01.00.6
Cocaine response after cond. not corrected0.00.00.10.2-0.2-0.20.20.20.10.30.30.0
Cocaine response before conditioning1.72.13.31.3-1.2-1.21.21.21.2-1.8-1.8-1.7
Saline control response0.20.20.5-0.30.40.4-0.4-0.4-0.40.50.50.7
Bone: connectivity density0.20.30.60.4-0.4-0.40.40.40.5-0.8-0.8-0.7
Bone: cortical apparent density1.92.62.91.7-1.7-1.71.71.71.7-1.4-1.4-1.6
Bone: cortical area0.40.70.80.9-0.9-0.90.90.90.9-0.6-0.6-0.8
Bone: cortical porosity1.31.51.6-1.21.21.2-1.2-1.2-1.21.31.31.3
Bone: cortical porosity1.61.81.8-1.31.31.3-1.3-1.3-1.31.31.31.3
Bone: cortical thickness0.40.60.80.9-0.9-0.90.90.90.9-0.5-0.5-0.8
Bone: cortical thickness0.10.10.1-0.20.30.3-0.3-0.3-0.2-0.3-0.3-0.3
Bone: cortical tissue density1.72.42.61.6-1.6-1.61.61.61.6-1.4-1.4-1.5
Condit. Reinf. active minus inactive responses0.30.40.7-0.80.60.6-0.6-0.6-0.60.40.40.6
Condit. Reinf. active-inactive response ratio0.20.30.8-0.50.30.4-0.4-0.4-0.40.60.60.9
Condit. Reinf. active responses0.20.20.3-0.60.50.5-0.5-0.5-0.50.10.10.2
Condit. Reinf. inactive responses0.10.10.30.10.30.3-0.3-0.3-0.3-0.4-0.4-0.6
Incentive salience index mean0.20.30.6-0.80.50.5-0.5-0.5-0.50.30.30.5
Condit. Reinf. lever presses0.00.00.2-0.1-0.0-0.00.00.00.0-0.4-0.4-0.3
Condit. Reinf. active minus inactive responses0.00.10.1-0.30.30.3-0.3-0.3-0.3-0.0-0.00.0
Condit. Reinf. active-inactive response ratio0.50.60.8-0.80.90.9-0.9-0.9-0.90.50.50.4
Condit. Reinf. active responses0.10.10.10.3-0.2-0.20.20.20.2-0.4-0.4-0.3
Condit. Reinf. inactive responses0.70.91.11.0-1.0-1.01.01.01.0-0.8-0.8-0.6
Condit. Reinf. lever presses0.40.50.7-0.70.80.8-0.8-0.8-0.80.50.50.5
Condit. Reinf. lever reinforcers received0.00.10.10.3-0.2-0.20.20.20.2-0.3-0.3-0.3
Conditioned reinforcement - actives0.61.01.11.1-1.1-1.11.11.11.1-0.9-0.9-0.8
Conditioned reinforcement - inactives0.60.91.01.0-1.0-1.01.01.01.0-0.8-0.8-1.0
Conditioned locomotion2.33.03.21.8-1.8-1.81.81.81.8-1.7-1.7-1.4
Patch foraging indifference point 0 sec0.00.10.10.4-0.3-0.30.30.30.3-0.3-0.3-0.1
Patch foraging indifference point AUC1.01.51.91.4-1.3-1.31.31.31.3-1.0-1.0-0.9
Delay disc. indifference point, 0s delay1.11.21.4-1.21.21.2-1.2-1.2-1.11.01.01.0
Delay disc. indifference point, 16s delay0.00.00.0-0.20.10.1-0.1-0.1-0.10.10.10.2
Delay disc. indifference point, 2s delay0.20.30.4-0.40.50.5-0.5-0.5-0.50.60.60.5
Delay disc. indifference point, 24s delay0.10.10.2-0.50.30.3-0.3-0.3-0.30.20.20.2
Delay disc. indifference point, 4s delay0.40.40.5-0.50.70.7-0.7-0.7-0.70.60.60.6
Delay disc. indifference point, 8s delay0.40.40.6-0.80.70.7-0.7-0.7-0.70.50.50.5
Indifference point function ln k3.46.08.8-3.02.72.7-2.7-2.7-2.71.61.61.7
Indifference point function log k3.46.08.8-3.02.72.7-2.7-2.7-2.71.61.61.7
Patch foraging total patch changes 0 sec0.00.00.00.1-0.1-0.10.10.10.1-0.1-0.10.1
Patch foraging total patch changes 12 sec1.31.62.61.6-1.4-1.41.41.41.4-1.0-1.0-0.8
Patch foraging total patch changes 18 sec0.50.81.31.1-1.0-1.01.01.01.0-0.7-0.7-0.4
Patch foraging total patch changes 24 sec0.71.31.61.3-1.2-1.21.21.21.2-1.0-1.0-0.8
Patch foraging total patch changes 6 sec2.53.84.72.2-2.1-2.12.12.12.0-1.6-1.6-1.7
Patch foraging time to switch 0 sec0.81.72.01.4-1.4-1.41.41.41.4-1.1-1.1-1.0
Patch foraging water rate 0 sec1.53.13.3-1.71.81.8-1.8-1.8-1.81.71.71.7
Patch foraging water rate 12 sec1.32.73.7-1.91.81.8-1.8-1.8-1.71.31.31.4
Patch foraging water rate 18 sec1.01.62.5-1.61.41.4-1.4-1.4-1.40.70.70.7
Patch foraging water rate 24 sec2.33.34.5-2.12.12.0-2.0-2.0-2.01.21.21.1
Patch foraging water rate 6 sec2.74.05.5-2.32.22.2-2.2-2.2-2.21.61.61.3
Seeking ratio, delayed vs. immediate footshock0.20.20.3-0.50.40.4-0.4-0.4-0.40.40.40.6
Distance traveled before self-admin4.35.66.92.6-2.6-2.62.62.62.5-2.0-2.0-1.6
Distance traveled after self-admin4.15.16.02.5-2.4-2.42.42.42.4-1.9-1.9-1.7
Extensor digitorum longus weight0.10.51.0-1.00.80.8-0.8-0.8-0.80.30.30.4
Bone: elastic displacement0.00.00.1-0.20.10.1-0.1-0.1-0.10.30.30.4
Bone: elastic work0.00.00.00.0-0.1-0.10.10.10.1-0.0-0.0-0.1
Bone: endosteal estimation0.10.10.20.4-0.3-0.30.30.30.3-0.4-0.4-0.3
Bone: endosteal perimeter0.40.80.8-0.90.90.9-0.9-0.9-0.90.90.90.9
Epididymis fat weight0.00.00.1-0.10.20.2-0.2-0.2-0.20.20.20.1
Delta time in closed arm before/after self-admin0.30.30.5-0.70.60.6-0.6-0.6-0.60.20.2-0.1
Delta time in open arm before/after self-admin0.10.10.10.4-0.3-0.30.30.30.3-0.2-0.20.3
Diff in mean of infusions in LGA sessions0.00.00.00.2-0.2-0.20.20.20.2-0.0-0.0-0.2
Delay discount exponential model param0.30.30.30.5-0.6-0.60.60.60.6-0.5-0.5-0.5
Extinction: sum of active levers before priming0.00.00.10.2-0.2-0.20.20.20.20.10.10.3
Active lever presses in extinction session 60.10.10.10.2-0.2-0.20.20.20.20.20.20.4
Bone: final force1.21.92.31.4-1.3-1.41.41.41.4-1.4-1.4-1.5
Bone: final moment0.81.21.71.0-1.0-1.01.11.11.1-1.2-1.2-1.3
Food consumed during 24 hour testing period0.71.01.31.1-1.2-1.21.11.11.1-0.7-0.7-0.6
Glucose2.64.15.42.3-2.2-2.22.22.22.2-1.7-1.7-1.2
Heart weight1.21.92.11.4-1.3-1.31.31.31.3-1.5-1.5-1.4
Delay discount hyperbolic model param0.50.50.50.7-0.7-0.70.70.70.7-0.7-0.7-0.7
Intermittent access intake day 1-15 change0.10.20.5-0.30.30.3-0.3-0.3-0.30.60.60.7
Intermittent access intake escalation0.10.20.4-0.30.30.3-0.3-0.3-0.30.50.50.6
Intermittent access intake escalation 20.70.81.2-0.80.80.8-0.8-0.8-0.81.11.11.0
Intermitt. access day 1 inactive lever presses1.24.54.62.1-2.1-2.12.12.12.1-2.1-2.1-2.0
Intermitt. access day 15 inactive lever presses0.61.21.51.2-1.2-1.21.21.21.2-1.0-1.0-0.7
Intermitt. access escalation Index0.30.40.50.7-0.6-0.60.60.60.6-0.5-0.5-0.6
Intermittent access day 1 total infusions6.811.011.53.3-3.3-3.33.33.33.3-3.4-3.4-3.2
Intermittent access day 15 total infusions2.84.24.52.1-2.1-2.12.12.12.1-2.0-2.0-1.6
Intermittent access terminal intake (last 3 days)2.33.03.61.9-1.9-1.91.91.81.8-1.6-1.6-1.2
Intermittent access total infusions5.26.26.72.6-2.6-2.62.62.62.6-2.4-2.4-2.1
Intermittent access day 1 locomotion2.12.73.31.5-1.6-1.61.61.61.6-1.8-1.8-1.8
Intermittent access day 15 total locomotion0.40.80.91.0-1.0-1.01.01.01.0-0.8-0.8-0.7
Intermittent access total locomotion3.23.84.21.9-1.9-1.91.91.92.0-1.9-1.9-2.0
Intermittent access standard deviation0.71.41.71.3-1.3-1.31.31.31.3-1.1-1.1-0.7
Left kidney weight5.827.231.05.6-5.6-5.65.55.55.5-4.5-4.5-4.5
Right kidney weight3.013.713.83.6-3.7-3.73.73.73.7-3.7-3.7-3.7
Cocaine induced anxiety0.10.10.40.3-0.3-0.30.30.30.3-0.2-0.2-0.6
Post-drug Anxiety0.30.30.4-0.50.50.5-0.5-0.5-0.50.60.60.1
Baseline Anxiety0.81.01.1-1.01.01.0-1.0-1.0-1.00.90.90.8
Tail length2.911.312.33.4-3.3-3.33.33.33.3-3.5-3.5-3.3
Length with tail2.310.211.33.4-3.2-3.23.23.23.2-3.1-3.1-3.1
Length without tail0.51.62.11.5-1.4-1.41.41.41.3-0.9-0.9-1.0
Times rat made contact with spout0.40.40.50.6-0.7-0.70.70.70.7-0.5-0.5-0.6
Lifetime Intake4.55.45.82.4-2.4-2.42.42.42.4-2.3-2.3-2.0
Liver weight, left0.81.31.71.3-1.2-1.21.21.21.2-0.9-0.9-1.2
Liver weight, right2.34.06.91.8-1.8-1.81.81.81.9-2.2-2.2-2.6
Locomotor activity1.32.13.11.3-1.3-1.31.31.31.3-1.6-1.6-1.8
Locomotor testing distance0.40.81.01.0-0.8-0.80.80.80.8-0.9-0.9-1.0
Locomotor testing rearing0.51.11.41.1-0.9-0.90.90.91.0-1.1-1.1-1.2
Locomotion in novel chamber0.20.30.50.7-0.6-0.60.60.60.6-0.4-0.4-0.2
Locomotion in novel chamber post-restriction0.10.20.5-0.10.20.2-0.2-0.2-0.20.60.60.7
Fecal boli incidents, locomotor time 13.75.47.82.8-2.6-2.62.62.52.5-1.8-1.8-1.5
Change in fecal boli incidents, locomotor task4.34.25.1-2.32.22.2-2.2-2.2-2.21.81.81.6
Time >=10cm from walls, locomotor time 12.72.93.41.8-1.8-1.81.81.81.8-1.4-1.4-1.2
Bouts of movement, locomotor time 10.00.00.10.10.10.1-0.1-0.1-0.1-0.2-0.2-0.3
Total resting periods, locomotor time 10.00.00.10.2-0.0-0.00.00.00.0-0.3-0.3-0.3
Rest time, locomotor task time 10.20.30.60.8-0.5-0.50.50.50.5-0.5-0.5-0.3
Distance moved, locomotor task time 10.40.61.0-1.00.80.8-0.8-0.8-0.80.70.70.6
Vertical activity count, locomotor time 10.51.11.5-1.21.11.1-1.1-1.1-1.11.01.00.9
Time >=10cm from walls, locomotor time 21.31.92.21.4-1.5-1.51.51.51.5-1.3-1.3-0.8
Bouts of movement, locomotor time 20.00.00.1-0.20.00.0-0.0-0.0-0.0-0.0-0.00.3
Total resting periods, locomotor time 20.00.00.1-0.30.20.2-0.2-0.2-0.20.10.10.3
Rest time, locomotor task time 20.81.01.31.1-0.9-0.90.90.91.0-1.0-1.0-1.1
Distance moved, locomotor task time 20.00.00.1-0.10.10.1-0.1-0.1-0.10.20.20.3
Vertical activity count, locomotor time 20.30.50.7-0.80.60.6-0.6-0.6-0.60.60.60.8
Light reinforcement 10.30.80.90.8-0.9-0.90.90.90.9-1.0-1.0-0.8
Light reinforcement 20.10.20.5-0.1-0.1-0.10.10.10.1-0.7-0.7-0.6
Bone: marrow area0.00.10.10.4-0.3-0.30.30.30.3-0.2-0.2-0.2
Bone: maximum diameter0.10.20.30.5-0.5-0.50.50.50.5-0.3-0.3-0.5
Bone: maximum force0.50.91.01.0-0.9-0.90.90.90.9-0.8-0.8-1.0
Bone: maximum moment0.20.30.40.6-0.6-0.60.60.60.6-0.6-0.6-0.7
Mean time between licks in bursts0.30.81.0-0.80.90.9-0.9-0.9-0.91.01.01.0
Mean num. licks in bursts0.20.30.30.3-0.6-0.60.60.60.6-0.4-0.4-0.5
Cd content in liver6.87.68.92.5-2.7-2.72.72.72.7-3.0-3.0-2.9
Co content in liver0.00.10.10.2-0.3-0.30.30.30.3-0.2-0.2-0.2
Cu content in liver0.81.02.20.6-0.7-0.70.70.70.7-1.4-1.4-1.5
Fe content in liver0.30.41.2-0.40.10.1-0.1-0.1-0.0-1.1-1.1-0.9
K content in liver0.00.00.20.10.00.0-0.0-0.0-0.00.40.40.2
Mg content in liver0.60.61.10.6-0.7-0.70.70.70.7-0.8-0.8-1.1
Mn content in liver0.91.01.31.0-1.0-1.01.01.01.0-1.2-1.2-1.0
Na content in liver0.00.00.10.0-0.1-0.10.10.10.1-0.3-0.3-0.0
Rb content in liver3.44.04.41.9-2.1-2.12.12.12.1-1.9-1.9-1.8
Se content in liver0.10.10.40.3-0.1-0.10.10.10.1-0.7-0.7-0.2
Sr content in liver3.53.13.9-1.51.71.7-1.7-1.7-1.71.81.82.0
Zn content in liver2.93.33.51.9-1.8-1.81.81.81.8-1.7-1.7-1.7
Bone: minimum diameter0.40.80.91.0-0.8-0.80.80.80.8-0.9-0.9-0.9
Time in familiar zone, hab. session 12.01.92.71.2-1.3-1.31.31.31.3-1.6-1.6-1.3
Time in novel zone, hab. session 10.10.10.3-0.20.20.2-0.2-0.2-0.20.60.60.3
Total zone transitions, hab. session 10.10.10.2-0.30.40.4-0.4-0.4-0.40.10.1-0.2
Total locomotion distance, hab. session 10.20.30.4-0.50.70.6-0.6-0.6-0.60.40.40.1
Locomotion velocity, hab. session 10.50.71.0-0.91.01.0-1.0-1.0-1.00.50.50.3
Time in familiar zone, hab. session 20.60.61.60.4-0.5-0.50.50.50.5-1.3-1.3-1.0
Time in novel zone, hab. session 20.91.02.0-0.60.70.7-0.7-0.7-0.71.41.41.3
Total zone transitions, hab. session 21.82.32.9-1.41.41.4-1.4-1.4-1.51.71.71.4
Total locomotion distance, hab. session 22.33.03.1-1.81.81.8-1.8-1.8-1.71.81.81.6
Locomotion velocity, hab. session 21.92.63.1-1.61.61.6-1.6-1.6-1.61.81.81.5
Novel to familiar place preference ratio1.01.11.21.1-1.1-1.11.11.11.1-1.0-1.0-0.9
Novelty place preference1.41.61.71.3-1.3-1.31.31.31.3-1.2-1.2-1.1
Time in novel zone, NPP test1.92.02.11.4-1.4-1.41.41.41.4-1.4-1.4-1.2
Total zone transitions, NPP test1.11.61.9-1.21.41.4-1.4-1.4-1.31.11.10.9
Total locomotion distance, NPP test1.31.72.0-1.41.41.4-1.4-1.4-1.41.31.31.0
Locomotion velocity, NPP test2.02.93.1-1.71.71.7-1.7-1.7-1.71.81.81.4
Intraocular pressure0.10.10.50.0-0.2-0.20.20.20.3-0.4-0.4-0.7
Delta distance traveled before/after self-admin0.10.10.10.3-0.3-0.30.30.30.3-0.2-0.2-0.3
Delta ambulatory time before/after self-admin0.00.00.0-0.10.10.1-0.1-0.1-0.10.10.10.0
Parametrial fat weight0.30.81.00.9-1.0-1.01.01.00.9-0.8-0.8-0.5
Pavlov. Cond. lever latency1.72.22.61.5-1.4-1.41.41.41.4-1.6-1.6-1.5
Pavlov. Cond. magazine entry latency0.10.20.6-0.00.00.0-0.0-0.1-0.10.80.80.7
Pavlov. Cond. change in total contacts1.92.02.5-1.21.31.4-1.3-1.4-1.41.61.61.5
Pavlov. Cond. index score0.60.71.4-0.70.70.7-0.7-0.7-0.71.21.21.0
Pavlov. Cond. latency score0.81.11.9-0.90.80.9-0.9-0.9-0.91.41.41.2
Pavlov. Cond. lever contacts2.93.54.5-1.81.71.7-1.7-1.7-1.82.12.12.0
Pavlov. Cond. magazine entry number0.10.20.3-0.50.50.5-0.5-0.5-0.5-0.0-0.00.1
Pavlov. Cond. intertrial magazine entries1.72.12.8-1.51.71.7-1.7-1.7-1.61.01.01.0
Pavlov. Cond. lever-magazine prob. diff.0.81.01.6-0.90.80.8-0.8-0.8-0.81.31.31.0
Pavlov. Cond. response bias0.40.51.0-0.60.60.6-0.6-0.6-0.61.01.00.8
Pavlov. Cond. lever latency0.10.20.20.3-0.4-0.40.40.40.4-0.5-0.5-0.2
Pavlov. Cond. magazine entry latency1.21.51.9-1.41.31.3-1.3-1.3-1.31.01.00.9
Pavlov. Cond. change in total contacts0.10.10.2-0.30.40.4-0.4-0.4-0.40.30.30.0
Pavlov. Cond. index score0.81.11.3-1.01.11.1-1.1-1.1-1.11.01.00.8
Pavlov. Cond. latency score1.01.41.6-1.11.31.3-1.3-1.3-1.31.11.10.9
Pavlov. Cond. lever contacts0.00.00.00.10.10.1-0.1-0.1-0.10.20.20.0
Pavlov. Cond. magazine entry number0.30.30.40.5-0.6-0.60.60.60.6-0.7-0.7-0.5
Pavlov. Cond. intertrial magazine entries0.10.10.20.2-0.3-0.30.30.30.3-0.4-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.91.31.4-1.01.21.2-1.2-1.2-1.21.11.10.9
Pavlov. Cond. response bias0.20.20.3-0.40.50.5-0.5-0.5-0.50.50.50.3
Time in closed arm before self-admin3.74.85.82.4-2.4-2.42.42.42.3-1.9-1.9-1.6
Time in closed arm after self-admin0.40.40.40.6-0.6-0.60.60.60.6-0.6-0.6-0.4
Time in open arm before self-admin1.01.11.4-1.21.11.1-1.1-1.1-1.10.90.90.8
Time in open arm after self-admin0.50.60.6-0.80.80.8-0.8-0.8-0.80.60.60.7
Bone: periosteal estimation0.20.40.60.8-0.7-0.70.70.70.7-0.5-0.5-0.6
Bone: periosteal perimeter0.00.00.00.2-0.2-0.20.20.20.20.10.1-0.0
Bone: post-yield work0.00.00.2-0.40.20.2-0.2-0.2-0.2-0.0-0.0-0.1
Progressive ratio test 1 active lever presses4.35.35.42.3-2.3-2.32.32.32.3-2.2-2.2-2.3
Progressive ratio test 1 breakpoint4.96.06.12.4-2.5-2.52.52.52.5-2.4-2.4-2.4
Progressive ratio test 1 inactive lever presses2.43.44.01.7-1.8-1.81.81.81.8-2.0-2.0-2.0
Progressive ratio test 2 active lever presses5.86.87.02.6-2.6-2.62.62.62.6-2.6-2.6-2.4
Progressive ratio test 2 breakpoint6.27.17.32.7-2.7-2.72.72.72.7-2.7-2.7-2.4
Progressive ratio test 2 inactive lever presses4.77.78.22.9-2.9-2.92.92.92.9-2.6-2.6-2.5
Incentive Sensitization - Responses3.75.35.52.3-2.3-2.32.32.32.3-2.3-2.3-2.0
Incentive Sensitization - Breakpoint3.95.05.22.3-2.3-2.32.32.32.3-2.3-2.3-1.9
Sum of active levers in priming session hrs 5-60.20.20.4-0.30.30.3-0.3-0.3-0.30.60.60.6
Progressive ratio0.10.10.20.1-0.2-0.20.20.20.2-0.4-0.4-0.3
Food seeking constrained by brief footshock1.92.42.71.6-1.5-1.51.51.51.5-1.5-1.5-1.5
Seeking ratio, punishment vs. effort0.10.10.30.5-0.4-0.40.40.40.4-0.2-0.2-0.4
Retroperitoneal fat weight0.41.82.01.2-1.4-1.41.41.41.3-1.4-1.4-1.2
Reaction time number correct0.61.21.3-1.11.11.1-1.1-1.1-1.11.01.01.1
Reaction time mean minus median0.71.82.51.2-1.3-1.31.31.31.3-1.3-1.3-1.6
Reaction time mean minus median AUC1.63.94.71.9-2.0-2.02.02.02.0-1.9-1.9-2.2
Reaction time num false alarms0.10.10.30.5-0.2-0.20.20.20.20.40.40.0
Reaction time num false alarms AUC0.10.10.50.30.10.1-0.1-0.1-0.10.70.70.4
Reaction time trials correct on left0.61.21.3-1.11.11.1-1.1-1.1-1.11.01.01.1
Reaction time trials on left0.61.21.3-1.11.11.1-1.1-1.1-1.11.11.11.1
Reaction time mean0.20.30.30.5-0.6-0.60.60.60.6-0.3-0.3-0.5
Reaction time mean AUC0.00.00.10.1-0.2-0.20.20.20.20.00.0-0.2
Median of all reaction times0.00.00.10.0-0.1-0.10.10.10.10.30.30.1
Reaction time omissions0.00.00.1-0.20.10.1-0.1-0.1-0.10.30.3-0.3
Reaction time false alarm rate0.10.10.50.7-0.4-0.40.40.40.40.20.2-0.1
Reaction time premature initiation rate1.21.72.5-0.91.21.2-1.3-1.3-1.31.41.41.6
Reaction time premature initiations1.73.03.8-1.41.71.7-1.7-1.7-1.71.81.82.0
Std. dev. reaction times0.30.60.90.7-0.8-0.80.80.80.8-0.6-0.6-0.9
Reaction time trials completed0.61.21.3-1.11.11.1-1.1-1.1-1.11.11.11.1
Reaction time trials AUC0.40.80.9-1.00.90.9-0.9-0.9-0.90.90.90.9
Run reversals in cocaine runway, females0.30.30.40.6-0.6-0.60.60.60.6-0.6-0.6-0.4
Run reversals in cocaine runway, males3.03.03.51.9-1.8-1.81.81.81.8-1.4-1.4-1.6
Latency to leave start box in cocaine runway0.70.81.6-0.80.70.7-0.7-0.7-0.71.01.01.3
Latency to leave start box in cocaine runway, F0.10.10.2-0.40.20.2-0.2-0.2-0.20.30.30.5
Latency to leave start box in cocaine runway, M1.81.62.8-1.11.11.1-1.1-1.1-1.21.51.51.7
Std. dev. time between licks in bursts0.20.30.9-0.30.40.4-0.4-0.4-0.40.80.80.9
Total sessions with >9 infusions1.72.12.21.5-1.5-1.51.51.51.5-1.5-1.5-1.3
Short access day 1 total inactive lever presses0.10.10.2-0.30.30.3-0.3-0.3-0.30.40.40.5
Short access day 10 total inactive lever presses0.10.30.40.6-0.6-0.60.60.60.6-0.4-0.4-0.2
Short access day 1 total infusions2.02.62.81.6-1.6-1.61.61.61.6-1.7-1.7-1.4
Short access day 10 total infusions3.64.65.02.1-2.2-2.22.22.22.2-2.2-2.2-1.9
Short access total infusions2.43.03.21.8-1.8-1.81.81.81.8-1.8-1.8-1.5
Short access day 1 locomotion0.40.50.70.6-0.7-0.70.70.70.7-0.8-0.8-0.7
Short access day 10 total locomotion2.03.73.91.9-1.9-1.91.91.91.9-2.0-2.0-1.9
Short access total locomotion3.23.94.41.9-1.9-1.91.91.91.9-2.1-2.1-2.0
One hour access (0.3 mA shock)3.23.74.12.0-2.0-2.02.02.02.0-1.8-1.8-1.5
Compulsive drug intake0.91.11.31.0-1.0-1.01.01.01.0-1.1-1.1-1.1
One hour access (shock baseline)0.81.21.51.2-1.2-1.21.21.21.2-0.9-0.9-0.8
Social response proportion0.10.10.3-0.0-0.0-0.00.00.00.1-0.5-0.5-0.5
Social responses0.10.10.20.4-0.4-0.40.40.40.40.00.0-0.2
Social time0.50.61.4-0.40.60.6-0.6-0.6-0.61.21.21.0
Soleus weight0.30.91.3-1.10.90.9-0.9-0.9-0.90.90.91.1
Bone: stiffness0.61.01.41.2-1.0-1.01.01.01.0-1.0-1.0-1.1
Tibialis anterior weight0.00.10.2-0.50.30.3-0.3-0.3-0.3-0.2-0.2-0.0
Time to tail flick, vehicle, before self-admin0.50.50.9-0.60.60.6-0.6-0.6-0.60.90.90.9
Time to tail flick, vehicle, after self-admin0.60.81.40.9-0.9-0.90.90.90.9-0.6-0.6-1.2
Time to tail flick, test, before self-admin0.20.20.30.3-0.3-0.30.30.30.3-0.6-0.6-0.5
Time to tail flick, test, after self-admin0.50.50.70.6-0.7-0.70.70.70.7-0.8-0.8-0.6
Delta time to tail flick, vehicle, before/after SA2.12.03.31.3-1.3-1.31.31.31.3-1.4-1.4-1.8
Delta time to tail flick, test, before/after SA0.30.30.4-0.50.50.5-0.5-0.5-0.50.60.60.7
Tibia length0.30.81.11.1-1.0-1.01.01.01.0-0.7-0.7-0.5
Ambulatory time before self-admin2.53.74.72.2-2.1-2.12.12.12.1-1.5-1.5-1.2
Ambulatory time after self-admin3.13.74.62.2-2.1-2.12.12.12.1-1.6-1.6-1.2
Bone: tissue strength0.10.10.4-0.0-0.0-0.00.00.00.0-0.6-0.6-0.5
Total heroin consumption0.30.40.50.6-0.7-0.70.70.70.7-0.5-0.5-0.3
Bone: trabecular number0.20.40.8-0.90.80.7-0.7-0.7-0.70.10.10.2
Bone: trabecular spacing0.00.10.20.0-0.0-0.00.00.00.1-0.5-0.5-0.4
Bone: trabecular thickness0.50.70.91.0-1.0-1.01.01.00.9-0.4-0.4-0.4
Bone: trabecular tissue density0.30.50.80.9-0.8-0.80.80.80.8-0.2-0.2-0.2
Water consumed over 24 hours0.00.00.0-0.1-0.0-0.00.00.00.0-0.2-0.20.0
Number of responses in last shaping day0.70.81.00.8-0.8-0.80.80.80.9-1.0-1.0-1.0