Eif3f

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	mRNA stability	Eif3f	0.03	0.02	2.4e-04	0.01	0.02	0.02	0.01	1.2e-02	4.4e-04	3.3e-04	3.5e-03
2	PL	mRNA stability	Eif3f	0.03	0.02	2.2e-03	0	0.02	-0	0.01	2.3e-01	3.5e-03	3.9e-01	5.2e-02
3	Brain	mRNA stability	Eif3f	0.07	0.05	9.7e-06	0.05	0.05	0.04	0.04	8.2e-06	4.2e-05	7.4e-05	1.4e-04
4	Brain	gene expression	Eif3f	0.04	0.03	4.6e-04	0.03	0.02	0.02	0.02	1.7e-03	3.5e-03	4.7e-03	5.2e-03
5	BLA	gene expression	Eif3f	0.06	0.05	3.7e-03	0.08	0.03	0.06	0.07	4.3e-05	7.6e-03	3.0e-04	9.7e-05
6	Liver	gene expression	Eif3f	0.04	0.03	1.0e-04	0.03	0.03	0.03	0.03	4.0e-04	1.1e-04	4.7e-04	4.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6
Bone: apparent density	0.1	0.1	0.2	-0.2	0.5	-0.4	0.3	0.2	0.1
Area under the delay curve	0.4	0.6	1.0	-0.9	1.0	-0.4	1.0	0.4	0.7
BMI with tail	5.1	17.6	28.1	5.2	-5.3	4.2	-4.2	-3.8	-0.7
BMI without tail	3.5	18.7	28.6	5.1	-5.3	4.0	-4.6	-4.4	-1.2
Body weight	2.5	11.1	15.9	3.7	-4.0	2.6	-3.8	-3.7	-1.5
Weight adjusted by age	0.8	2.3	3.4	1.8	-1.8	1.4	-1.5	-1.7	-0.2
Bone surface	0.1	0.1	0.3	-0.3	0.6	-0.4	0.4	0.2	0.2
Bone volume	0.0	0.0	0.1	0.3	0.0	0.1	0.0	-0.0	0.3
Breakpoint value in progressive ratio session	0.5	0.8	1.7	0.9	-0.5	1.3	0.2	1.0	1.1
Number of licking bursts	0.1	0.4	0.6	-0.6	0.7	-0.3	0.7	0.8	0.7
Context. condit. distance diff. score	0.6	0.8	1.6	0.9	-0.7	1.3	0.3	0.3	1.2
Locomotion velocity, session 1	0.3	0.4	1.3	0.0	0.1	0.3	0.5	1.1	0.8
Locomotion distance, session 1	0.4	0.5	1.0	0.7	-0.6	1.0	0.2	0.6	0.8
Locomotion velocity, session 2	0.3	0.4	0.8	0.7	-0.5	0.9	0.2	0.5	0.7
Locomotion distance, session 2	2.0	2.8	6.4	2.1	-2.0	2.5	-0.6	-0.4	1.2
Locomotion velocity, session 3	0.2	0.3	0.6	0.5	-0.8	0.5	-0.7	-0.2	-0.2
Locomotion distance, session 3	0.2	0.2	0.4	0.3	-0.7	0.4	-0.5	-0.4	-0.2
Stereotopy head waving bouts, day 3	0.2	0.2	0.4	-0.5	0.6	-0.6	0.4	0.6	0.1
Stereotopy head waving duration, day 3	0.1	0.1	0.3	0.5	-0.4	0.3	-0.1	0.2	0.3
Locomotion velocity, session 7	1.9	2.1	5.8	0.4	0.1	1.5	1.6	1.4	2.4
Locomotion distance, session 7	0.6	0.8	1.6	-0.4	0.4	0.4	1.1	1.2	1.3
Stereotopy head waving bouts, day 7	0.0	0.0	0.0	0.1	-0.1	0.0	-0.0	0.1	0.0
Stereotopy head waving duration, day 7	0.7	0.9	1.2	1.1	-1.1	0.7	-1.1	-0.9	-0.5
Locomotion velocity, session 8	1.4	1.7	4.2	0.0	0.5	0.8	1.6	1.7	2.0
Locomotion distance, session 8	1.6	2.3	5.1	1.8	-1.7	2.3	-0.1	-0.2	1.5
Degree of sensitization distance	0.6	0.6	1.6	0.6	-0.3	1.0	0.6	0.5	1.3
Degree of sensitization stereotypy	0.1	0.2	0.3	0.6	-0.5	0.6	-0.3	-0.2	0.1
Conditioned locomotion	0.7	0.8	1.7	-1.3	0.8	-1.3	0.2	0.4	-0.9
Cocaine response after cond. corrected	0.5	0.7	1.7	-0.3	0.4	0.1	1.0	1.3	1.1
Cocaine response after cond. not corrected	0.2	0.3	0.5	0.5	-0.6	0.7	-0.1	0.3	0.6
Cocaine response before conditioning	1.3	1.5	2.2	1.3	-1.5	1.2	-1.5	-1.3	-0.3
Saline control response	1.3	1.8	3.8	0.6	-1.1	0.1	-1.8	-2.0	-1.5
Bone: connectivity density	0.0	0.0	0.1	0.0	0.3	-0.1	0.3	0.1	0.3
Bone: cortical apparent density	0.6	1.0	1.8	-1.3	1.2	-1.1	0.8	1.0	-0.1
Bone: cortical area	0.1	0.2	0.4	0.6	-0.4	0.7	-0.0	-0.1	0.5
Bone: cortical porosity	0.1	0.1	0.2	-0.2	0.3	-0.4	0.1	-0.2	-0.2
Bone: cortical porosity	0.4	0.4	0.9	-0.7	0.8	-1.0	0.4	0.0	-0.4
Bone: cortical thickness	0.3	0.5	0.9	1.0	-0.7	1.0	-0.2	-0.3	0.5
Bone: cortical thickness	0.6	0.7	1.5	1.1	-0.6	1.2	0.2	0.1	1.1
Bone: cortical tissue density	0.6	0.9	1.7	-1.3	1.1	-1.1	0.7	0.9	-0.1
Condit. Reinf. active minus inactive responses	0.9	1.0	2.6	-0.2	-0.1	-0.8	-1.1	-1.2	-1.6
Condit. Reinf. active-inactive response ratio	1.0	1.0	2.8	-0.3	0.2	-1.1	-0.9	-1.1	-1.7
Condit. Reinf. active responses	1.0	1.3	3.5	-0.4	0.1	-1.1	-1.2	-1.2	-1.9
Condit. Reinf. inactive responses	0.3	0.4	0.8	0.0	-0.4	-0.1	-0.9	-0.7	-0.8
Incentive salience index mean	0.8	1.0	2.6	-0.8	0.5	-1.3	-0.6	-0.7	-1.6
Condit. Reinf. lever presses	0.6	0.9	2.1	-1.1	1.0	-1.4	0.1	0.1	-1.1
Condit. Reinf. active minus inactive responses	0.2	0.3	0.6	0.5	-0.5	0.3	-0.7	-0.8	-0.5
Condit. Reinf. active-inactive response ratio	0.0	0.1	0.1	-0.1	-0.0	-0.1	-0.2	-0.4	-0.4
Condit. Reinf. active responses	0.4	0.6	1.0	0.9	-0.9	0.7	-0.8	-1.0	-0.3
Condit. Reinf. inactive responses	1.0	1.5	2.5	1.6	-1.5	1.3	-1.1	-1.1	0.0
Condit. Reinf. lever presses	2.0	2.9	4.6	2.0	-2.1	1.8	-1.6	-1.6	-0.4
Condit. Reinf. lever reinforcers received	0.3	0.4	0.7	0.6	-0.7	0.5	-0.7	-0.8	-0.3
Conditioned reinforcement - actives	0.2	0.8	1.5	0.9	-1.0	1.2	-0.8	-0.9	-0.0
Conditioned reinforcement - inactives	0.0	0.1	0.3	-0.4	0.4	-0.1	0.5	0.0	0.5
Conditioned locomotion	0.6	0.9	1.9	-0.0	-0.3	-0.4	-1.1	-1.4	-1.4
Patch foraging indifference point 0 sec	1.0	2.7	4.4	1.7	-1.7	1.3	-2.0	-2.1	-1.0
Patch foraging indifference point AUC	0.0	0.1	0.2	0.2	0.0	0.1	0.4	0.4	0.4
Delay disc. indifference point, 0s delay	0.2	0.2	0.6	0.3	-0.4	0.5	-0.1	-0.8	0.2
Delay disc. indifference point, 16s delay	0.7	0.9	1.9	-0.9	0.9	0.0	1.4	0.6	1.3
Delay disc. indifference point, 2s delay	0.6	0.7	1.4	-1.1	1.0	-1.2	0.5	0.2	-0.4
Delay disc. indifference point, 24s delay	0.0	0.1	0.4	-0.3	0.0	-0.0	-0.0	-0.6	0.0
Delay disc. indifference point, 4s delay	1.5	1.5	2.5	-1.6	1.5	-1.4	1.0	1.2	0.1
Delay disc. indifference point, 8s delay	0.1	0.2	0.6	-0.2	0.3	0.3	0.7	0.0	0.8
Indifference point function ln k	0.2	0.6	0.9	0.7	-0.9	0.7	-0.8	-0.8	-0.4
Indifference point function log k	0.2	0.6	0.9	0.7	-0.9	0.7	-0.8	-0.8	-0.4
Patch foraging total patch changes 0 sec	1.1	3.3	5.3	1.7	-1.9	1.3	-2.3	-2.3	-1.2
Patch foraging total patch changes 12 sec	0.3	0.5	1.0	1.0	-0.6	0.6	-0.6	-0.8	-0.3
Patch foraging total patch changes 18 sec	0.6	1.5	2.3	1.3	-1.2	0.7	-1.5	-1.5	-1.0
Patch foraging total patch changes 24 sec	0.1	0.3	0.6	0.3	-0.3	0.1	-0.8	-0.6	-0.5
Patch foraging total patch changes 6 sec	0.7	1.1	2.1	1.4	-1.1	1.4	-0.8	-0.8	0.2
Patch foraging time to switch 0 sec	0.4	1.5	2.4	-1.4	1.5	-1.1	1.2	1.3	0.3
Patch foraging water rate 0 sec	0.1	0.3	0.5	0.6	-0.7	0.5	-0.6	-0.7	-0.3
Patch foraging water rate 12 sec	1.0	4.0	6.7	2.5	-2.6	2.4	-1.6	-1.6	0.2
Patch foraging water rate 18 sec	0.4	0.8	1.9	1.0	-1.2	1.4	-0.5	-0.5	0.5
Patch foraging water rate 24 sec	0.7	0.9	2.1	1.1	-1.2	1.5	-0.5	-0.4	0.6
Patch foraging water rate 6 sec	0.0	0.0	0.1	-0.2	-0.1	-0.0	-0.2	-0.1	-0.3
Seeking ratio, delayed vs. immediate footshock	1.1	1.6	2.5	-1.6	1.6	-1.2	1.2	1.4	0.2
Distance traveled before self-admin	0.1	0.3	0.6	-0.8	0.8	-0.7	0.5	0.0	-0.2
Distance traveled after self-admin	0.4	0.7	1.6	0.5	-0.5	-0.1	-0.9	-1.3	-1.0
Extensor digitorum longus weight	0.3	1.2	2.8	1.7	-1.2	1.4	-0.1	-0.3	0.9
Bone: elastic displacement	0.1	0.1	0.2	0.3	-0.1	0.3	0.0	-0.4	0.4
Bone: elastic work	0.1	0.2	0.3	0.5	-0.4	0.5	-0.1	-0.3	0.5
Bone: endosteal estimation	0.1	0.3	0.6	-0.4	0.5	-0.1	0.7	0.8	0.5
Bone: endosteal perimeter	0.2	0.6	1.1	-0.4	0.7	0.0	1.1	0.9	1.0
Epididymis fat weight	0.2	0.9	1.4	1.2	-1.2	0.8	-1.0	-0.9	-0.2
Delta time in closed arm before/after self-admin	1.3	1.2	3.3	-0.2	0.0	1.1	1.2	1.0	1.8
Delta time in open arm before/after self-admin	2.1	2.5	4.8	1.2	-1.4	0.2	-2.2	-1.8	-2.0
Diff in mean of infusions in LGA sessions	0.1	0.1	0.2	-0.1	0.2	0.3	0.4	0.3	0.4
Delay discount exponential model param	0.5	0.7	1.1	1.0	-1.0	0.5	-1.0	-0.5	-0.6
Extinction: sum of active levers before priming	0.1	0.2	0.6	-0.1	0.3	0.1	0.6	0.8	0.3
Active lever presses in extinction session 6	1.0	1.0	2.5	1.0	-0.4	1.6	0.4	0.7	1.3
Bone: final force	0.2	0.3	0.8	-0.2	0.2	-0.7	-0.4	-0.4	-0.9
Bone: final moment	0.2	0.3	0.9	0.0	-0.1	-0.5	-0.6	-0.6	-0.9
Food consumed during 24 hour testing period	0.2	0.3	0.5	0.5	-0.6	0.5	-0.7	-0.7	0.1
Glucose	0.1	0.1	0.3	-0.3	0.5	-0.1	0.5	0.4	0.3
Heart weight	0.7	1.2	1.8	1.2	-1.3	1.0	-1.2	-1.1	-0.2
Delay discount hyperbolic model param	0.5	0.7	1.2	1.1	-1.1	0.7	-0.9	-0.5	-0.4
Intermittent access intake day 1-15 change	0.1	0.4	0.7	-0.8	0.7	-0.4	0.9	0.4	0.5
Intermittent access intake escalation	0.1	0.5	0.9	-0.9	0.8	-0.6	0.9	0.4	0.5
Intermittent access intake escalation 2	0.1	0.2	0.3	-0.4	0.3	-0.4	0.5	0.3	0.4
Intermitt. access day 1 inactive lever presses	0.1	0.7	1.6	-1.3	1.0	-0.6	0.9	0.6	0.3
Intermitt. access day 15 inactive lever presses	0.0	0.2	0.6	-0.4	0.1	0.1	0.5	-0.0	0.8
Intermitt. access escalation Index	0.1	0.3	0.9	0.3	-0.5	-0.2	-0.8	-0.4	-0.9
Intermittent access day 1 total infusions	0.0	0.1	0.2	0.0	0.0	-0.1	-0.3	-0.4	-0.4
Intermittent access day 15 total infusions	0.1	0.4	0.7	-0.8	0.8	-0.6	0.7	0.1	0.1
Intermittent access terminal intake (last 3 days)	0.0	0.0	0.1	-0.2	0.2	-0.3	0.2	-0.1	-0.0
Intermittent access total infusions	0.1	0.1	0.2	-0.3	0.3	-0.4	-0.1	-0.4	-0.4
Intermittent access day 1 locomotion	0.3	0.6	1.2	-0.8	0.9	-1.1	0.1	-0.2	-0.9
Intermittent access day 15 total locomotion	0.1	0.5	1.4	-0.3	0.2	-0.9	-0.5	-0.8	-1.2
Intermittent access total locomotion	0.4	0.5	1.1	-0.6	0.5	-0.9	-0.3	-0.7	-1.0
Intermittent access standard deviation	0.1	0.3	1.1	0.2	-0.2	0.6	0.5	0.1	1.1
Left kidney weight	0.4	2.9	4.4	2.0	-2.1	1.4	-1.9	-1.7	-0.9
Right kidney weight	0.6	4.5	6.7	2.6	-2.6	2.2	-2.1	-2.1	-0.5
Cocaine induced anxiety	0.1	0.2	0.4	-0.5	0.4	-0.6	0.1	-0.1	-0.3
Post-drug Anxiety	1.4	1.6	2.4	-1.3	1.5	-0.7	1.4	1.5	0.6
Baseline Anxiety	0.6	1.1	2.5	-0.8	1.1	-0.1	1.2	1.6	0.8
Tail length	0.3	1.4	3.3	-0.8	0.3	-1.3	-1.1	-1.3	-1.8
Length with tail	0.1	0.6	1.2	-0.9	0.6	-1.1	-0.2	-0.3	-0.9
Length without tail	0.2	1.1	2.1	-1.4	1.3	-1.4	0.6	0.6	-0.5
Times rat made contact with spout	0.1	0.1	0.1	-0.4	0.4	-0.3	0.2	0.3	-0.0
Lifetime Intake	0.1	0.1	0.3	0.0	-0.1	-0.1	-0.2	-0.6	-0.2
Liver weight, left	0.3	0.5	1.1	0.1	-0.1	-0.7	-0.8	-0.6	-1.1
Liver weight, right	0.1	0.1	0.3	-0.1	0.3	-0.5	-0.3	-0.2	-0.6
Locomotor activity	1.8	2.8	6.2	2.2	-1.9	2.5	-1.1	-0.9	0.8
Locomotor testing distance	1.8	4.4	8.2	2.7	-2.5	2.9	-1.6	-1.5	0.5
Locomotor testing rearing	0.4	1.5	2.9	1.5	-1.5	1.7	-1.0	-0.9	0.2
Locomotion in novel chamber	0.1	0.1	0.2	0.4	-0.2	0.0	-0.3	0.1	-0.5
Locomotion in novel chamber post-restriction	0.3	0.8	1.5	-1.2	1.1	-0.7	0.6	1.1	0.0
Fecal boli incidents, locomotor time 1	1.1	3.0	5.7	-2.2	2.4	-2.3	1.3	0.2	-0.6
Change in fecal boli incidents, locomotor task	1.8	1.9	5.6	0.3	0.2	1.3	1.5	1.4	2.4
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.5	0.2	-0.1	0.1	-0.3	-0.7	-0.4
Bouts of movement, locomotor time 1	0.0	0.0	0.1	-0.0	0.3	-0.0	0.2	0.1	0.1
Total resting periods, locomotor time 1	0.3	0.3	0.6	-0.3	0.7	-0.1	0.8	0.6	0.6
Rest time, locomotor task time 1	3.0	4.9	9.2	-2.0	2.7	-0.7	3.0	2.0	2.2
Distance moved, locomotor task time 1	1.2	3.3	6.5	1.5	-2.0	0.3	-2.5	-1.5	-2.1
Vertical activity count, locomotor time 1	0.5	3.3	5.6	1.5	-2.1	0.6	-2.4	-2.0	-1.8
Time >=10cm from walls, locomotor time 2	0.4	1.1	2.6	1.5	-1.1	1.6	-0.3	-0.1	0.6
Bouts of movement, locomotor time 2	0.0	0.1	0.1	-0.4	0.2	-0.4	-0.1	-0.0	-0.3
Total resting periods, locomotor time 2	0.0	0.2	0.4	-0.6	0.5	-0.4	0.3	0.2	0.0
Rest time, locomotor task time 2	0.7	1.2	2.5	-0.7	1.1	0.1	1.6	1.0	1.4
Distance moved, locomotor task time 2	1.6	2.1	3.7	1.9	-1.9	1.1	-1.7	-0.9	-0.9
Vertical activity count, locomotor time 2	0.1	0.3	0.5	0.7	-0.7	0.5	-0.4	-0.6	-0.2
Light reinforcement 1	0.0	0.1	0.2	0.4	-0.1	-0.1	-0.3	-0.5	-0.3
Light reinforcement 2	0.4	0.8	1.8	1.3	-0.9	1.0	-0.7	-0.9	0.3
Bone: marrow area	0.1	0.4	0.7	-0.5	0.6	-0.2	0.7	0.8	0.5
Bone: maximum diameter	0.2	0.4	0.9	0.9	-0.6	1.0	-0.2	-0.2	0.6
Bone: maximum force	0.1	0.2	0.4	-0.4	0.4	-0.6	-0.0	-0.1	-0.4
Bone: maximum moment	0.1	0.1	0.2	-0.1	0.1	-0.4	-0.3	-0.4	-0.5
Mean time between licks in bursts	0.0	0.1	0.4	-0.0	0.3	-0.6	0.1	-0.4	-0.4
Mean num. licks in bursts	0.1	0.2	0.4	0.2	-0.3	-0.0	-0.5	-0.5	-0.6
Cd content in liver	2.1	2.4	4.0	-2.0	2.0	-2.0	1.2	0.9	-0.4
Co content in liver	0.3	0.4	0.8	-0.2	0.3	0.2	0.8	0.9	0.8
Cu content in liver	2.3	2.8	5.2	0.9	-1.1	-0.4	-2.1	-2.3	-2.2
Fe content in liver	0.0	0.1	0.1	-0.3	0.1	-0.4	-0.1	-0.0	-0.2
K content in liver	0.8	0.8	1.7	0.4	-0.5	0.1	-1.0	-1.3	-1.2
Mg content in liver	3.9	4.3	7.7	2.2	-2.2	1.2	-2.3	-2.8	-1.3
Mn content in liver	1.0	1.2	2.4	0.2	-0.5	-0.4	-1.4	-1.5	-1.5
Na content in liver	0.2	0.3	0.6	0.6	-0.6	0.8	-0.1	-0.2	0.3
Rb content in liver	2.3	2.7	7.3	-1.0	0.4	-1.9	-1.4	-1.4	-2.7
Se content in liver	0.5	0.6	1.4	-0.8	0.3	-0.9	-0.5	-0.6	-1.2
Sr content in liver	1.1	1.0	2.8	0.9	-1.1	1.7	-0.0	0.3	1.1
Zn content in liver	3.5	4.1	6.8	2.6	-2.4	2.0	-1.8	-2.1	-0.4
Bone: minimum diameter	0.4	0.7	1.4	-0.4	0.6	0.2	1.1	1.1	1.2
Time in familiar zone, hab. session 1	0.8	0.9	2.7	-0.1	0.1	0.9	1.0	1.0	1.7
Time in novel zone, hab. session 1	0.0	0.1	0.1	0.1	0.3	-0.4	0.2	0.1	-0.2
Total zone transitions, hab. session 1	0.5	0.6	1.0	0.8	-1.0	0.6	-0.9	-1.0	-0.5
Total locomotion distance, hab. session 1	0.2	0.2	0.7	0.1	-0.3	0.1	-0.6	-0.9	-0.4
Locomotion velocity, hab. session 1	0.5	0.7	1.9	0.3	-0.7	0.1	-1.1	-1.4	-0.9
Time in familiar zone, hab. session 2	0.8	1.0	1.7	0.9	-1.3	1.3	-0.9	-0.9	0.0
Time in novel zone, hab. session 2	0.1	0.1	0.3	0.5	-0.1	0.1	-0.1	-0.1	0.1
Total zone transitions, hab. session 2	1.5	1.9	3.2	1.7	-1.8	1.3	-1.4	-1.3	-0.4
Total locomotion distance, hab. session 2	1.4	1.9	2.9	1.7	-1.6	1.3	-1.3	-1.4	-0.2
Locomotion velocity, hab. session 2	1.3	1.8	2.5	1.6	-1.6	1.1	-1.4	-1.5	-0.4
Novel to familiar place preference ratio	1.1	1.4	3.3	-0.5	0.3	-1.5	-1.0	-1.2	-1.8
Novelty place preference	0.7	0.8	1.9	-0.3	0.3	-1.2	-0.7	-1.0	-1.4
Time in novel zone, NPP test	0.5	0.6	1.4	-0.1	0.2	-1.0	-0.7	-0.9	-1.2
Total zone transitions, NPP test	0.3	0.4	1.0	0.9	-0.8	1.0	-0.2	-0.2	0.5
Total locomotion distance, NPP test	1.3	1.8	4.0	1.7	-1.6	2.0	-0.5	-0.6	1.0
Locomotion velocity, NPP test	1.2	1.7	3.8	1.6	-1.6	1.9	-0.5	-0.7	0.9
Intraocular pressure	0.1	0.2	0.7	-0.5	0.6	-0.8	0.0	0.1	-0.2
Delta distance traveled before/after self-admin	1.1	1.2	1.9	1.2	-1.3	0.6	-1.4	-1.2	-0.8
Delta ambulatory time before/after self-admin	0.3	0.5	0.9	0.5	-0.6	-0.1	-1.0	-0.7	-0.9
Parametrial fat weight	0.8	1.9	3.3	1.3	-1.2	0.6	-1.7	-1.8	-1.2
Pavlov. Cond. lever latency	0.3	0.4	1.0	0.6	-0.8	1.0	-0.2	0.2	0.6
Pavlov. Cond. magazine entry latency	0.1	0.1	0.3	0.5	-0.2	0.5	0.2	-0.2	0.4
Pavlov. Cond. change in total contacts	1.7	1.8	3.2	-1.5	1.8	-1.8	1.3	0.9	-0.0
Pavlov. Cond. index score	0.0	0.1	0.2	-0.0	0.4	-0.2	0.3	-0.1	0.0
Pavlov. Cond. latency score	0.0	0.1	0.1	-0.0	0.4	-0.4	0.2	-0.2	-0.2
Pavlov. Cond. lever contacts	0.1	0.1	0.3	0.0	0.2	-0.5	-0.2	-0.5	-0.5
Pavlov. Cond. magazine entry number	0.0	0.0	0.1	0.0	-0.3	0.1	-0.4	0.0	-0.1
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.3	-0.4	0.1	-0.4	-0.5	-0.3	-0.6
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.5	-0.3	0.7	-0.5	0.5	0.1	0.0
Pavlov. Cond. response bias	0.1	0.2	0.4	-0.3	0.6	-0.4	0.6	0.2	0.1
Pavlov. Cond. lever latency	3.3	4.6	8.7	-2.8	2.7	-2.9	1.1	1.2	-0.8
Pavlov. Cond. magazine entry latency	1.7	2.4	4.3	2.1	-2.1	1.8	-1.1	-1.2	0.2
Pavlov. Cond. change in total contacts	1.3	3.2	5.6	2.4	-2.4	2.4	-1.1	-1.1	0.4
Pavlov. Cond. index score	2.6	4.2	7.5	2.7	-2.7	2.6	-1.2	-1.4	0.4
Pavlov. Cond. latency score	2.5	4.1	7.4	2.7	-2.6	2.7	-1.1	-1.2	0.6
Pavlov. Cond. lever contacts	2.9	4.3	8.0	2.7	-2.6	2.8	-1.1	-1.3	0.7
Pavlov. Cond. magazine entry number	1.5	2.0	3.9	-1.9	1.7	-2.0	0.5	0.7	-0.8
Pavlov. Cond. intertrial magazine entries	0.7	1.5	3.1	0.6	-0.9	0.0	-1.7	-1.8	-1.4
Pavlov. Cond. lever-magazine prob. diff.	2.7	4.2	7.6	2.8	-2.7	2.7	-1.2	-1.3	0.5
Pavlov. Cond. response bias	3.1	4.3	7.8	2.8	-2.6	2.8	-1.1	-1.3	0.8
Time in closed arm before self-admin	0.9	1.5	3.0	1.7	-1.5	0.9	-1.2	-1.2	-0.5
Time in closed arm after self-admin	0.9	1.0	2.5	0.5	0.0	0.9	1.2	1.1	1.6
Time in open arm before self-admin	1.3	1.6	3.4	-1.9	1.6	-1.3	1.0	1.1	0.3
Time in open arm after self-admin	1.4	1.5	3.1	0.2	-0.7	-0.2	-1.8	-1.6	-1.7
Bone: periosteal estimation	0.1	0.2	0.7	0.3	-0.1	0.6	0.4	0.4	0.8
Bone: periosteal perimeter	0.1	0.2	0.6	0.4	-0.1	0.6	0.3	0.1	0.8
Bone: post-yield work	0.1	0.3	0.6	-0.0	0.1	-0.6	-0.5	-0.6	-0.8
Progressive ratio test 1 active lever presses	0.2	0.4	0.7	-0.7	0.9	-0.7	0.7	0.5	0.1
Progressive ratio test 1 breakpoint	0.3	0.6	1.0	-0.9	1.0	-0.8	0.8	0.5	0.1
Progressive ratio test 1 inactive lever presses	0.0	0.1	0.1	-0.3	0.1	0.2	-0.2	-0.3	-0.3
Progressive ratio test 2 active lever presses	0.1	0.1	0.2	-0.4	0.4	-0.3	0.1	0.1	-0.3
Progressive ratio test 2 breakpoint	0.1	0.1	0.2	-0.4	0.4	-0.3	0.1	0.1	-0.3
Progressive ratio test 2 inactive lever presses	0.0	0.0	0.1	-0.1	-0.1	0.1	-0.0	-0.2	0.1
Incentive Sensitization - Responses	0.1	0.3	0.8	0.7	-0.7	0.9	-0.4	-0.3	0.1
Incentive Sensitization - Breakpoint	0.2	0.4	0.9	0.8	-0.8	0.9	-0.5	-0.4	0.0
Sum of active levers in priming session hrs 5-6	0.5	0.4	1.0	0.8	-0.9	1.0	-0.5	-0.0	0.1
Progressive ratio	0.6	1.8	4.2	-0.0	-0.7	-0.4	-1.7	-1.8	-2.0
Food seeking constrained by brief footshock	0.1	0.2	0.4	-0.5	0.5	-0.6	0.3	0.2	-0.1
Seeking ratio, punishment vs. effort	0.4	0.8	2.0	0.4	0.2	0.4	1.1	1.1	1.4
Retroperitoneal fat weight	0.5	2.2	3.7	1.3	-1.3	0.3	-1.8	-1.9	-1.6
Reaction time number correct	0.1	0.5	0.9	0.7	-0.4	1.0	0.4	0.2	1.0
Reaction time mean minus median	0.6	3.8	7.7	2.5	-2.5	2.8	-1.0	-0.8	1.0
Reaction time mean minus median AUC	0.5	3.3	6.3	2.3	-2.4	2.5	-1.1	-0.9	0.8
Reaction time num false alarms	0.4	0.6	1.4	0.1	-0.4	-0.1	-1.1	-1.2	-1.1
Reaction time num false alarms AUC	0.4	0.9	1.9	0.2	-0.6	0.0	-1.4	-1.4	-1.2
Reaction time trials correct on left	0.1	0.5	0.9	0.7	-0.4	1.0	0.4	0.2	1.0
Reaction time trials on left	0.2	0.6	1.2	0.9	-0.5	1.1	0.4	0.2	1.1
Reaction time mean	0.7	1.5	2.6	1.6	-1.6	1.1	-1.1	-1.1	-0.4
Reaction time mean AUC	0.3	0.7	1.3	1.0	-1.1	0.5	-0.8	-0.9	-0.6
Median of all reaction times	0.6	1.0	1.4	1.2	-1.2	0.4	-1.0	-1.2	-0.8
Reaction time omissions	1.2	2.0	4.1	1.7	-1.1	2.0	0.5	0.5	1.8
Reaction time false alarm rate	0.8	1.1	2.2	-0.0	-0.5	-0.3	-1.5	-1.4	-1.5
Reaction time premature initiation rate	0.9	1.5	2.8	1.6	-1.4	1.7	-0.6	-0.7	0.6
Reaction time premature initiations	0.6	1.8	4.2	1.8	-1.4	2.0	-0.1	-0.3	1.2
Std. dev. reaction times	0.7	2.4	4.2	2.0	-2.0	2.0	-0.9	-0.8	0.5
Reaction time trials completed	0.2	0.6	1.2	0.9	-0.5	1.1	0.4	0.2	1.1
Reaction time trials AUC	0.2	0.6	1.3	0.9	-0.6	1.1	0.3	0.1	1.0
Run reversals in cocaine runway, females	0.1	0.1	0.3	-0.1	0.5	-0.5	0.4	-0.2	0.1
Run reversals in cocaine runway, males	0.4	0.5	1.1	-1.0	0.9	-0.6	0.6	0.3	0.0
Latency to leave start box in cocaine runway	0.9	1.2	2.0	-0.9	0.9	0.1	1.4	1.4	1.4
Latency to leave start box in cocaine runway, F	0.5	0.7	0.9	-0.9	0.9	-0.5	1.0	0.9	0.6
Latency to leave start box in cocaine runway, M	0.7	0.7	2.0	0.1	-0.1	1.1	0.8	0.6	1.4
Std. dev. time between licks in bursts	0.2	0.3	0.8	-0.2	0.0	-0.6	-0.6	-0.6	-0.9
Total sessions with >9 infusions	0.2	0.3	0.6	0.7	-0.6	0.8	-0.4	-0.5	0.1
Short access day 1 total inactive lever presses	0.7	1.4	3.1	-1.8	1.5	-1.5	0.9	0.5	-0.1
Short access day 10 total inactive lever presses	0.1	0.6	1.4	-0.1	-0.5	-0.7	-0.8	-1.2	-0.8
Short access day 1 total infusions	0.5	0.9	1.3	0.9	-1.1	1.0	-1.1	-1.1	-0.3
Short access day 10 total infusions	0.3	0.5	0.8	0.8	-0.8	0.7	-0.5	-0.9	0.0
Short access total infusions	0.1	0.1	0.5	0.2	-0.3	0.2	-0.3	-0.7	-0.0
Short access day 1 locomotion	0.1	0.2	0.6	-0.8	0.5	0.0	0.1	-0.0	-0.1
Short access day 10 total locomotion	0.2	0.8	2.4	0.9	-0.9	1.6	-0.2	-0.3	0.7
Short access total locomotion	0.1	0.2	0.5	-0.2	0.1	-0.2	-0.4	-0.7	-0.7
One hour access (0.3 mA shock)	0.5	0.6	1.5	0.4	-0.4	1.2	0.5	0.3	1.2
Compulsive drug intake	0.3	0.4	1.0	-0.6	0.7	-0.3	0.7	1.0	0.4
One hour access (shock baseline)	0.2	0.4	1.2	0.2	-0.3	1.1	0.4	0.1	1.0
Social response proportion	0.5	0.6	1.0	1.0	-0.9	0.3	-0.7	-0.9	-0.7
Social responses	0.2	0.3	0.6	0.6	-0.4	0.7	0.3	0.3	0.8
Social time	0.7	1.1	1.9	1.4	-1.3	1.4	-0.7	-0.9	0.3
Soleus weight	0.0	0.1	0.2	0.4	-0.3	-0.1	-0.3	-0.2	-0.2
Bone: stiffness	1.5	2.8	4.6	-2.1	2.1	-2.1	1.3	1.2	-0.3
Tibialis anterior weight	0.4	1.4	3.1	1.8	-1.4	1.4	-0.7	-0.7	0.4
Time to tail flick, vehicle, before self-admin	0.8	0.9	2.4	0.3	-0.7	-0.6	-1.2	-1.0	-1.5
Time to tail flick, vehicle, after self-admin	0.3	0.6	1.1	-0.6	0.7	-0.2	0.9	1.1	0.7
Time to tail flick, test, before self-admin	1.0	1.2	2.4	-0.5	-0.2	-1.3	-0.9	-1.4	-1.6
Time to tail flick, test, after self-admin	0.6	0.7	1.1	0.7	-0.7	-0.6	-1.0	-0.8	-1.0
Delta time to tail flick, vehicle, before/after SA	2.1	2.2	3.8	-1.1	1.5	-0.1	1.9	1.7	1.8
Delta time to tail flick, test, before/after SA	0.3	0.3	1.1	1.1	-0.6	0.7	-0.3	0.0	0.3
Tibia length	0.7	2.0	3.7	0.7	-1.1	-0.3	-1.9	-1.9	-1.6
Ambulatory time before self-admin	0.3	0.8	1.5	-1.1	1.2	-0.8	1.1	0.5	0.4
Ambulatory time after self-admin	0.3	0.5	1.1	-0.2	0.0	-0.7	-0.6	-1.0	-1.0
Bone: tissue strength	1.6	1.7	3.0	1.7	-1.6	1.7	-0.9	-0.8	0.4
Total heroin consumption	0.6	0.7	1.7	1.0	-0.8	1.3	-0.3	-0.5	0.4
Bone: trabecular number	0.3	0.5	1.0	-0.7	1.0	-0.6	0.9	0.7	0.4
Bone: trabecular spacing	1.2	1.7	2.6	1.3	-1.5	0.8	-1.6	-1.5	-0.9
Bone: trabecular thickness	0.2	0.3	0.6	-0.2	0.4	0.1	0.6	0.6	0.8
Bone: trabecular tissue density	1.3	2.3	5.1	-1.9	1.4	-2.3	-0.0	-0.1	-1.8
Water consumed over 24 hours	0.6	1.1	2.3	-0.9	0.9	-0.1	1.1	1.5	1.3
Number of responses in last shaping day	0.2	0.2	0.8	0.1	-0.3	0.6	-0.2	-0.9	-0.2