Hub : Genes

Ehd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr1_85784248_85784718 0.08 0.06 2.5e-09 0.06 0.07 0.07 0.06 1.6e-07 3.1e-08 5.4e-08 9.0e-08
2 BLA gene expression Ehd2 0.12 0.1 2.6e-04 0.02 0.02 0.01 0.01 2.1e-02 2.8e-02 1.3e-01 9.2e-02
3 Adipose intron excision ratio chr1_85784248_85786917 0.11 0.06 2.6e-14 0.1 0.11 0.11 0.11 4.0e-11 8.0e-12 4.2e-12 6.7e-12
4 Eye gene expression Ehd2 0.4 0.27 4.4e-03 0.15 0.1 0.12 0.12 2.7e-03 1.1e-02 7.2e-03 7.3e-03
5 NAcc intron excision ratio chr1_85782294_85783789 0.02 0.01 1.3e-03 0.01 0.01 0.01 0.01 2.2e-03 8.9e-03 2.3e-02 1.3e-02
6 NAcc gene expression Ehd2 0.06 0.05 2.0e-07 0.05 0.04 0.04 0.04 1.2e-07 2.1e-07 2.4e-07 6.6e-07
7 Brain gene expression Ehd2 0.09 0.06 2.5e-09 0.09 0.1 0.08 0.09 5.1e-09 3.8e-09 3.0e-08 5.6e-09
8 Adipose mRNA stability Ehd2 0.77 0.15 0.0e+00 0.3 0.31 0.31 0.31 4.4e-34 5.0e-35 4.3e-35 4.0e-35
9 Adipose gene expression Ehd2 0.15 0.08 0.0e+00 0.18 0.18 0.17 0.18 7.5e-20 7.9e-20 2.3e-18 3.7e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.30.5-0.30.70.40.5-0.50.60.70.50.6
Area under the delay curve0.20.30.5-0.70.30.60.7-0.30.50.30.60.2
BMI with tail1.03.54.91.6-2.0-1.6-1.72.0-2.0-2.2-1.8-1.9
BMI without tail2.06.17.22.3-2.6-2.3-2.32.5-2.7-2.7-2.5-2.4
Body weight2.29.811.73.4-2.7-3.1-3.43.0-3.3-3.0-3.3-2.8
Weight adjusted by age0.71.11.61.2-0.8-1.1-1.31.1-0.9-0.8-0.9-1.1
Bone surface0.30.51.11.1-0.3-0.9-1.00.3-0.50.0-0.8-0.2
Bone volume0.10.10.40.60.2-0.5-0.4-0.10.00.4-0.20.2
Breakpoint value in progressive ratio session1.31.53.0-1.71.01.41.4-0.91.30.91.30.9
Number of licking bursts1.72.73.91.5-2.0-1.6-1.41.7-1.7-1.7-1.5-1.7
Context. condit. distance diff. score0.00.00.00.20.2-0.1-0.20.10.1-0.1-0.1-0.1
Locomotion velocity, session 10.70.81.0-0.81.00.90.7-1.00.91.00.61.0
Locomotion distance, session 10.10.10.40.30.4-0.1-0.2-0.40.50.60.10.4
Locomotion velocity, session 21.41.62.31.2-1.2-1.2-1.51.1-1.4-1.0-1.5-1.1
Locomotion distance, session 21.01.42.51.5-1.0-1.3-1.60.9-1.1-0.8-1.4-0.9
Locomotion velocity, session 30.10.10.20.3-0.3-0.3-0.40.3-0.3-0.3-0.4-0.3
Locomotion distance, session 30.20.20.6-0.20.80.30.1-0.50.50.70.30.5
Stereotopy head waving bouts, day 30.10.20.40.1-0.6-0.2-0.00.5-0.3-0.6-0.1-0.5
Stereotopy head waving duration, day 30.10.10.2-0.1-0.5-0.00.20.30.1-0.40.1-0.3
Locomotion velocity, session 71.41.52.0-1.01.31.01.0-1.31.41.41.21.3
Locomotion distance, session 70.10.10.2-0.20.50.20.2-0.40.30.40.20.4
Stereotopy head waving bouts, day 70.40.40.60.7-0.5-0.7-0.70.8-0.5-0.5-0.5-0.8
Stereotopy head waving duration, day 70.30.40.60.7-0.6-0.7-0.60.8-0.5-0.5-0.5-0.8
Locomotion velocity, session 80.20.30.8-0.20.50.30.4-0.40.90.50.70.4
Locomotion distance, session 80.10.20.50.7-0.0-0.5-0.70.3-0.1-0.2-0.5-0.3
Degree of sensitization distance0.00.00.10.0-0.4-0.10.00.1-0.0-0.2-0.0-0.1
Degree of sensitization stereotypy0.91.01.41.1-0.7-1.1-1.21.1-1.0-0.8-0.9-1.1
Conditioned locomotion0.10.10.20.2-0.4-0.2-0.30.2-0.2-0.3-0.3-0.2
Cocaine response after cond. corrected0.10.10.4-0.2-0.60.00.20.3-0.2-0.5-0.2-0.3
Cocaine response after cond. not corrected0.50.61.10.6-1.1-0.8-0.60.8-0.6-0.8-0.7-0.8
Cocaine response before conditioning2.32.74.72.2-1.4-2.2-2.11.4-1.3-1.0-1.5-1.4
Saline control response1.01.42.21.5-1.2-1.5-1.51.0-1.0-0.8-1.0-1.0
Bone: connectivity density0.00.00.1-0.10.20.10.1-0.10.20.30.10.2
Bone: cortical apparent density0.20.30.5-0.70.50.70.7-0.40.50.30.70.4
Bone: cortical area0.81.22.01.4-0.9-1.2-1.31.0-1.0-0.8-1.2-0.9
Bone: cortical porosity0.10.10.20.1-0.1-0.1-0.40.1-0.4-0.2-0.4-0.1
Bone: cortical porosity0.40.50.80.6-0.5-0.5-0.80.6-0.9-0.6-0.9-0.6
Bone: cortical thickness0.00.00.10.1-0.1-0.1-0.10.2-0.2-0.2-0.2-0.1
Bone: cortical thickness0.30.30.80.5-0.2-0.3-0.40.5-0.9-0.5-0.9-0.4
Bone: cortical tissue density0.30.40.7-0.80.60.80.8-0.50.60.40.70.5
Condit. Reinf. active minus inactive responses0.80.91.20.8-1.1-0.9-0.91.0-1.0-1.0-0.8-1.0
Condit. Reinf. active-inactive response ratio1.11.21.80.8-1.3-0.9-0.91.2-1.2-1.2-0.9-1.2
Condit. Reinf. active responses0.40.50.60.7-0.7-0.7-0.70.7-0.8-0.6-0.6-0.7
Condit. Reinf. inactive responses0.40.40.8-0.30.80.40.4-0.80.70.90.50.8
Incentive salience index mean0.60.80.90.9-0.9-0.8-1.00.8-0.9-0.9-0.8-0.8
Condit. Reinf. lever presses0.20.30.50.6-0.3-0.5-0.70.4-0.7-0.5-0.7-0.4
Condit. Reinf. active minus inactive responses0.10.10.20.40.2-0.2-0.3-0.30.10.5-0.10.3
Condit. Reinf. active-inactive response ratio0.10.10.10.40.2-0.1-0.3-0.20.00.3-0.20.3
Condit. Reinf. active responses0.10.10.40.40.4-0.2-0.3-0.40.10.6-0.10.4
Condit. Reinf. inactive responses0.10.10.3-0.20.50.10.1-0.40.20.50.20.4
Condit. Reinf. lever presses0.50.71.21.1-0.8-1.1-1.00.7-0.7-0.6-0.8-0.6
Condit. Reinf. lever reinforcers received0.10.20.30.60.3-0.3-0.5-0.3-0.00.6-0.20.4
Conditioned reinforcement - actives1.42.43.21.4-1.8-1.3-1.11.7-1.6-1.8-1.5-1.7
Conditioned reinforcement - inactives0.50.82.00.8-1.4-1.0-0.70.9-0.6-0.6-0.6-1.1
Conditioned locomotion0.70.91.80.7-1.4-0.8-0.61.0-0.9-1.1-0.7-1.1
Patch foraging indifference point 0 sec0.00.10.2-0.0-0.4-0.20.00.30.1-0.10.1-0.4
Patch foraging indifference point AUC3.44.95.52.1-2.1-2.2-2.32.2-2.3-2.2-2.3-2.2
Delay disc. indifference point, 0s delay0.40.40.5-0.30.70.50.7-0.70.50.70.70.7
Delay disc. indifference point, 16s delay0.20.20.7-0.8-0.00.60.6-0.00.30.10.4-0.0
Delay disc. indifference point, 2s delay0.50.50.8-0.80.80.80.9-0.70.60.60.80.6
Delay disc. indifference point, 24s delay0.30.30.90.0-1.0-0.3-0.10.7-0.2-0.6-0.2-0.7
Delay disc. indifference point, 4s delay0.10.10.20.4-0.4-0.4-0.20.4-0.3-0.3-0.2-0.4
Delay disc. indifference point, 8s delay0.60.71.3-1.10.61.01.0-0.71.00.70.90.6
Indifference point function ln k2.34.15.8-1.52.01.62.0-2.02.42.42.31.8
Indifference point function log k2.34.15.8-1.52.01.62.0-2.02.42.42.31.8
Patch foraging total patch changes 0 sec0.00.10.30.1-0.4-0.2-0.10.40.0-0.2-0.0-0.5
Patch foraging total patch changes 12 sec1.62.12.51.3-1.4-1.4-1.51.6-1.4-1.4-1.5-1.5
Patch foraging total patch changes 18 sec1.11.72.21.3-1.3-1.4-1.51.3-1.1-1.3-1.2-1.3
Patch foraging total patch changes 24 sec1.22.12.41.5-1.5-1.5-1.51.6-1.2-1.4-1.3-1.5
Patch foraging total patch changes 6 sec1.11.72.21.0-1.4-1.2-1.11.5-1.2-1.4-1.1-1.5
Patch foraging time to switch 0 sec1.12.33.9-2.01.42.01.8-1.31.30.91.31.5
Patch foraging water rate 0 sec1.02.13.21.8-1.5-1.8-1.51.4-1.2-1.1-1.2-1.5
Patch foraging water rate 12 sec0.00.10.30.20.0-0.20.0-0.30.40.60.30.1
Patch foraging water rate 18 sec0.10.20.6-0.10.10.10.6-0.30.80.40.80.2
Patch foraging water rate 24 sec0.20.30.8-0.20.10.20.6-0.50.90.60.80.4
Patch foraging water rate 6 sec1.72.54.52.1-1.6-1.9-1.71.3-1.3-1.0-1.4-1.3
Seeking ratio, delayed vs. immediate footshock2.32.73.9-1.32.01.51.6-1.61.71.81.71.6
Distance traveled before self-admin0.10.10.20.40.0-0.4-0.20.10.10.30.1-0.2
Distance traveled after self-admin0.50.61.0-0.70.90.40.7-0.61.01.00.90.6
Extensor digitorum longus weight1.35.16.92.6-2.0-2.4-2.32.5-1.8-2.4-2.0-2.4
Bone: elastic displacement2.02.33.1-1.71.41.61.8-1.41.51.31.61.4
Bone: elastic work0.10.10.2-0.20.30.20.4-0.40.40.40.50.4
Bone: endosteal estimation0.10.20.60.8-0.0-0.6-0.7-0.0-0.10.3-0.50.0
Bone: endosteal perimeter0.10.10.40.6-0.2-0.6-0.50.10.10.1-0.2-0.1
Epididymis fat weight0.41.31.6-1.21.21.21.1-1.11.01.01.11.3
Delta time in closed arm before/after self-admin0.30.31.2-0.21.10.50.3-0.50.10.40.10.7
Delta time in open arm before/after self-admin0.30.30.90.5-1.0-0.7-0.40.3-0.2-0.3-0.2-0.5
Diff in mean of infusions in LGA sessions0.91.11.4-1.01.11.21.1-1.01.00.91.01.1
Delay discount exponential model param0.10.20.40.6-0.1-0.5-0.60.1-0.4-0.2-0.5-0.1
Extinction: sum of active levers before priming0.00.00.1-0.10.2-0.00.1-0.10.30.20.30.1
Active lever presses in extinction session 62.42.43.41.2-1.3-1.3-1.51.8-1.6-1.6-1.6-1.8
Bone: final force0.81.32.41.5-0.8-1.4-1.40.9-1.1-0.7-1.3-0.8
Bone: final moment0.81.42.71.6-0.8-1.5-1.40.9-1.1-0.6-1.3-0.8
Food consumed during 24 hour testing period3.04.14.7-1.92.22.02.0-1.92.02.02.21.9
Glucose1.92.94.2-1.91.51.92.1-1.61.61.41.71.6
Heart weight0.61.01.90.8-1.4-1.1-1.10.8-0.9-0.7-0.9-1.0
Delay discount hyperbolic model param0.10.10.30.5-0.1-0.4-0.50.1-0.3-0.1-0.4-0.0
Intermittent access intake day 1-15 change0.10.20.30.50.2-0.2-0.5-0.1-0.6-0.5-0.60.0
Intermittent access intake escalation0.20.30.60.70.0-0.4-0.80.2-0.8-0.7-0.8-0.2
Intermittent access intake escalation 20.10.10.6-0.10.80.30.1-0.40.10.10.10.4
Intermitt. access day 1 inactive lever presses0.10.41.10.3-1.0-0.6-0.30.9-0.4-0.7-0.4-0.9
Intermitt. access day 15 inactive lever presses0.40.70.91.0-0.8-0.9-0.90.6-0.9-0.8-0.9-0.9
Intermitt. access escalation Index0.10.10.3-0.1-0.20.1-0.20.1-0.5-0.4-0.40.0
Intermittent access day 1 total infusions0.81.33.21.0-1.8-1.1-0.80.9-1.0-1.1-0.9-1.2
Intermittent access day 15 total infusions0.30.40.90.5-0.7-0.3-0.50.4-0.9-1.0-0.8-0.5
Intermittent access terminal intake (last 3 days)0.10.20.40.3-0.6-0.2-0.20.2-0.5-0.6-0.4-0.3
Intermittent access total infusions0.81.01.80.9-1.3-0.8-0.70.9-1.0-1.1-0.9-1.0
Intermittent access day 1 locomotion0.10.10.7-0.1-0.8-0.00.3-0.30.30.10.3-0.0
Intermittent access day 15 total locomotion0.10.20.9-0.3-0.20.30.3-1.00.30.20.30.6
Intermittent access total locomotion0.10.10.90.3-0.9-0.3-0.1-0.3-0.0-0.10.0-0.1
Intermittent access standard deviation0.10.20.6-0.50.80.70.3-0.40.0-0.1-0.00.4
Left kidney weight4.521.029.75.4-4.4-5.2-5.04.3-4.2-3.8-4.3-4.3
Right kidney weight3.616.322.84.8-3.9-4.7-4.33.8-3.6-3.5-3.7-3.8
Cocaine induced anxiety0.20.30.6-0.40.40.30.5-0.70.80.80.70.5
Post-drug Anxiety0.20.20.5-0.40.40.20.2-0.70.60.70.50.5
Baseline Anxiety0.70.81.0-1.00.90.90.9-1.00.80.90.80.9
Tail length1.45.38.02.8-2.0-2.5-2.52.1-2.3-1.9-2.4-2.1
Length with tail0.83.35.52.3-1.4-2.1-2.21.5-1.7-1.4-2.0-1.5
Length without tail0.31.12.01.4-0.6-1.2-1.40.8-1.0-0.7-1.2-0.6
Times rat made contact with spout0.70.81.3-1.00.81.01.1-0.70.80.71.10.7
Lifetime Intake1.21.52.71.1-1.6-1.0-1.01.1-1.2-1.3-1.1-1.2
Liver weight, left4.98.29.83.1-2.4-2.9-3.12.7-3.0-2.8-3.0-2.7
Liver weight, right1.93.43.91.8-1.9-1.9-1.81.9-1.8-1.8-1.7-2.0
Locomotor activity1.62.53.51.4-1.9-1.6-1.31.7-1.4-1.8-1.2-1.7
Locomotor testing distance1.22.12.81.3-1.7-1.5-1.21.6-1.3-1.6-1.0-1.6
Locomotor testing rearing4.38.69.63.0-3.1-3.1-3.02.8-2.8-3.0-2.7-2.9
Locomotion in novel chamber2.33.04.0-2.01.11.61.9-1.52.01.72.01.5
Locomotion in novel chamber post-restriction0.50.91.0-1.01.01.00.7-0.91.00.81.01.0
Fecal boli incidents, locomotor time 10.00.00.1-0.10.30.20.2-0.2-0.10.20.00.2
Change in fecal boli incidents, locomotor task0.40.40.9-1.00.50.90.7-0.50.50.50.50.6
Time >=10cm from walls, locomotor time 10.10.10.2-0.3-0.10.20.4-0.30.0-0.00.20.2
Bouts of movement, locomotor time 11.11.21.7-1.01.21.10.5-1.31.31.21.01.2
Total resting periods, locomotor time 12.22.43.2-1.61.61.61.0-1.81.71.71.41.6
Rest time, locomotor task time 10.50.61.0-0.50.80.70.0-1.01.01.00.70.9
Distance moved, locomotor task time 10.91.42.10.9-1.4-1.1-0.61.3-1.3-1.3-1.1-1.5
Vertical activity count, locomotor time 10.10.40.80.2-0.9-0.5-0.10.7-0.6-0.7-0.5-0.7
Time >=10cm from walls, locomotor time 20.00.10.3-0.00.30.1-0.10.0-0.5-0.2-0.5-0.0
Bouts of movement, locomotor time 21.42.22.7-1.61.41.51.1-1.61.61.61.51.4
Total resting periods, locomotor time 21.73.03.9-1.71.51.71.3-1.92.01.81.81.6
Rest time, locomotor task time 21.82.22.9-1.31.21.31.4-1.61.71.61.71.6
Distance moved, locomotor task time 22.22.73.21.5-1.4-1.7-1.51.6-1.8-1.5-1.8-1.8
Vertical activity count, locomotor time 20.81.21.71.0-0.9-1.1-1.01.1-1.3-1.0-1.3-1.0
Light reinforcement 10.40.91.10.9-1.0-1.0-0.91.1-1.0-0.8-1.0-1.1
Light reinforcement 21.21.82.71.0-1.4-1.2-1.31.4-1.6-1.3-1.5-1.3
Bone: marrow area0.10.30.70.8-0.1-0.7-0.80.1-0.20.2-0.6-0.1
Bone: maximum diameter2.75.16.42.5-2.2-2.4-2.52.2-2.0-1.9-2.4-2.1
Bone: maximum force0.40.71.51.2-0.5-1.0-1.10.5-0.6-0.3-0.9-0.5
Bone: maximum moment0.40.61.61.3-0.4-1.1-1.10.5-0.6-0.2-0.9-0.4
Mean time between licks in bursts0.00.00.10.0-0.3-0.1-0.00.3-0.1-0.4-0.0-0.3
Mean num. licks in bursts3.14.96.4-2.12.52.22.1-2.22.22.22.22.2
Cd content in liver0.70.81.1-0.61.00.70.8-1.01.01.00.71.0
Co content in liver0.70.81.3-0.80.90.80.9-0.81.10.91.10.8
Cu content in liver0.60.71.11.0-0.8-1.0-0.90.8-0.7-0.6-0.7-0.9
Fe content in liver2.93.54.42.0-1.6-2.0-2.11.8-1.7-1.7-1.9-1.9
K content in liver0.90.91.31.1-0.8-1.0-1.10.9-0.8-0.8-0.9-0.8
Mg content in liver1.91.92.11.4-1.4-1.4-1.41.4-1.2-1.4-1.3-1.5
Mn content in liver0.60.70.90.9-0.9-0.8-0.90.8-0.8-0.9-0.8-0.8
Na content in liver0.00.00.10.1-0.0-0.0-0.30.3-0.0-0.3-0.1-0.2
Rb content in liver0.30.40.80.9-0.5-0.8-0.80.4-0.6-0.2-0.7-0.4
Se content in liver8.09.411.52.9-3.2-2.9-3.03.2-2.9-3.4-2.7-3.3
Sr content in liver0.20.20.5-0.7-0.30.60.6-0.00.2-0.20.2-0.1
Zn content in liver2.52.84.41.4-2.1-1.5-1.41.9-1.4-1.9-1.3-1.9
Bone: minimum diameter0.30.51.41.2-0.2-1.0-1.10.3-0.4-0.0-0.8-0.3
Time in familiar zone, hab. session 10.10.10.30.10.2-0.1-0.1-0.50.20.60.00.5
Time in novel zone, hab. session 11.31.32.11.0-1.1-1.0-0.91.4-0.9-1.4-0.9-1.4
Total zone transitions, hab. session 10.00.10.20.40.3-0.2-0.3-0.10.30.3-0.00.1
Total locomotion distance, hab. session 10.40.61.0-0.50.80.60.7-0.71.00.90.90.7
Locomotion velocity, hab. session 11.11.62.0-1.01.31.21.2-1.21.41.31.41.2
Time in familiar zone, hab. session 20.10.10.2-0.20.10.10.1-0.5-0.10.30.00.5
Time in novel zone, hab. session 20.30.30.50.5-0.3-0.4-0.50.7-0.3-0.5-0.5-0.7
Total zone transitions, hab. session 20.30.41.01.0-0.3-0.8-0.90.3-0.3-0.1-0.5-0.3
Total locomotion distance, hab. session 20.60.71.1-0.60.90.70.7-0.81.01.01.00.8
Locomotion velocity, hab. session 20.30.40.7-0.40.70.50.5-0.60.90.80.90.6
Novel to familiar place preference ratio0.60.71.10.9-0.9-1.0-0.71.0-0.5-0.8-0.5-1.0
Novelty place preference0.50.60.90.9-0.8-0.9-0.70.9-0.4-0.7-0.5-0.9
Time in novel zone, NPP test0.60.60.90.9-0.8-0.9-0.70.9-0.4-0.7-0.5-0.9
Total zone transitions, NPP test0.20.20.50.6-0.3-0.5-0.70.3-0.5-0.3-0.6-0.3
Total locomotion distance, NPP test0.00.00.10.3-0.2-0.3-0.30.2-0.1-0.1-0.1-0.2
Locomotion velocity, NPP test0.00.00.10.3-0.2-0.3-0.30.2-0.1-0.1-0.1-0.2
Intraocular pressure0.20.30.9-0.41.00.60.3-0.70.20.60.40.6
Delta distance traveled before/after self-admin0.40.40.8-0.90.60.70.7-0.50.60.40.60.6
Delta ambulatory time before/after self-admin0.30.30.7-0.80.40.60.7-0.40.60.30.60.5
Parametrial fat weight0.30.71.5-1.20.21.01.2-0.50.90.31.00.3
Pavlov. Cond. lever latency0.70.91.3-1.00.80.91.0-1.00.91.10.81.0
Pavlov. Cond. magazine entry latency0.81.01.80.9-0.8-0.7-0.81.0-1.1-1.3-1.0-1.0
Pavlov. Cond. change in total contacts0.10.10.2-0.30.30.40.3-0.20.0-0.00.10.2
Pavlov. Cond. index score1.01.32.01.1-1.0-1.0-1.11.1-1.3-1.4-1.2-1.2
Pavlov. Cond. latency score0.50.61.20.7-0.6-0.6-0.60.8-0.8-1.1-0.7-0.8
Pavlov. Cond. lever contacts0.60.70.90.9-0.7-0.8-0.80.8-0.8-1.0-0.7-0.8
Pavlov. Cond. magazine entry number0.70.81.3-0.90.60.70.9-0.81.11.11.10.8
Pavlov. Cond. intertrial magazine entries0.30.40.8-0.50.30.30.6-0.60.90.90.90.6
Pavlov. Cond. lever-magazine prob. diff.1.21.42.11.1-1.0-1.0-1.11.2-1.4-1.5-1.2-1.2
Pavlov. Cond. response bias2.02.53.41.5-1.4-1.4-1.51.5-1.8-1.8-1.7-1.5
Pavlov. Cond. lever latency0.20.20.4-0.50.40.50.6-0.50.60.30.60.4
Pavlov. Cond. magazine entry latency0.10.10.10.2-0.4-0.2-0.20.3-0.2-0.3-0.3-0.2
Pavlov. Cond. change in total contacts0.20.30.7-0.30.80.40.2-0.60.40.90.30.6
Pavlov. Cond. index score0.10.10.20.3-0.2-0.3-0.40.2-0.3-0.1-0.4-0.2
Pavlov. Cond. latency score0.00.00.0-0.0-0.1-0.0-0.1-0.0-0.10.1-0.10.0
Pavlov. Cond. lever contacts0.40.50.80.8-0.6-0.8-0.90.7-0.8-0.5-0.8-0.6
Pavlov. Cond. magazine entry number0.10.10.10.3-0.2-0.3-0.20.3-0.3-0.4-0.2-0.3
Pavlov. Cond. intertrial magazine entries0.00.00.10.30.3-0.1-0.2-0.10.20.20.20.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.30.5-0.4-0.5-0.50.4-0.5-0.2-0.5-0.3
Pavlov. Cond. response bias0.20.30.60.7-0.2-0.6-0.80.4-0.4-0.1-0.6-0.3
Time in closed arm before self-admin0.20.30.40.4-0.6-0.5-0.60.6-0.4-0.5-0.5-0.6
Time in closed arm after self-admin0.50.51.9-0.51.40.80.5-0.70.40.50.40.8
Time in open arm before self-admin0.10.10.2-0.40.40.30.5-0.10.30.40.40.1
Time in open arm after self-admin0.10.10.2-0.1-0.5-0.20.2-0.00.20.10.3-0.1
Bone: periosteal estimation0.40.91.91.4-0.6-1.2-1.30.6-0.7-0.3-1.1-0.5
Bone: periosteal perimeter0.30.61.41.2-0.5-1.1-1.10.5-0.4-0.3-0.8-0.5
Bone: post-yield work0.10.10.40.10.5-0.0-0.1-0.50.40.60.00.5
Progressive ratio test 1 active lever presses0.91.13.11.1-1.8-1.2-0.90.9-0.8-0.8-0.8-1.0
Progressive ratio test 1 breakpoint0.80.92.81.0-1.7-1.1-0.80.8-0.7-0.7-0.7-0.9
Progressive ratio test 1 inactive lever presses1.42.13.61.6-1.9-1.6-1.41.1-1.3-1.2-1.3-1.4
Progressive ratio test 2 active lever presses1.82.13.51.3-1.9-1.2-1.21.3-1.5-1.6-1.4-1.4
Progressive ratio test 2 breakpoint2.02.33.91.4-2.0-1.3-1.31.4-1.6-1.7-1.4-1.5
Progressive ratio test 2 inactive lever presses0.81.32.11.4-1.2-1.3-1.30.9-1.1-1.1-1.1-1.0
Incentive Sensitization - Responses0.91.21.71.0-1.3-1.0-1.01.0-1.2-1.3-1.1-1.1
Incentive Sensitization - Breakpoint1.01.31.91.0-1.3-1.0-1.01.0-1.3-1.4-1.1-1.1
Sum of active levers in priming session hrs 5-60.30.30.6-0.80.50.70.6-0.50.50.50.50.3
Progressive ratio0.10.20.5-0.20.60.4-0.1-0.60.40.40.40.7
Food seeking constrained by brief footshock3.23.94.9-1.52.21.62.0-2.12.12.21.92.1
Seeking ratio, punishment vs. effort0.60.81.5-0.70.90.81.2-0.90.91.00.90.9
Retroperitoneal fat weight0.20.92.8-1.70.51.41.5-0.40.6-0.10.90.4
Reaction time number correct1.32.53.31.5-1.8-1.6-1.51.7-1.6-1.6-1.5-1.6
Reaction time mean minus median0.41.01.3-1.01.11.00.8-1.21.01.01.01.1
Reaction time mean minus median AUC0.10.20.4-0.30.50.40.2-0.60.40.40.40.5
Reaction time num false alarms4.96.98.72.5-2.5-2.5-2.62.9-2.6-2.7-2.5-2.7
Reaction time num false alarms AUC3.55.47.32.2-2.3-2.2-2.22.7-2.2-2.5-2.1-2.4
Reaction time trials correct on left1.32.53.31.5-1.8-1.6-1.51.7-1.6-1.6-1.5-1.6
Reaction time trials on left1.42.63.41.5-1.8-1.6-1.51.7-1.6-1.6-1.6-1.6
Reaction time mean1.32.12.5-1.51.31.41.5-1.41.61.51.51.3
Reaction time mean AUC1.11.72.2-1.41.11.41.5-1.21.41.21.31.1
Median of all reaction times1.01.51.8-1.31.01.21.3-1.21.31.21.21.0
Reaction time omissions0.10.10.40.1-0.6-0.3-0.20.6-0.2-0.2-0.1-0.5
Reaction time false alarm rate0.70.91.40.9-0.8-0.9-0.91.2-0.9-1.1-0.8-1.0
Reaction time premature initiation rate1.72.43.2-1.71.01.41.6-1.41.71.61.81.6
Reaction time premature initiations0.30.61.0-0.90.20.60.8-0.50.90.81.00.7
Std. dev. reaction times0.71.31.6-1.11.01.11.1-1.11.31.11.21.1
Reaction time trials completed1.42.63.41.5-1.8-1.6-1.51.7-1.6-1.6-1.6-1.6
Reaction time trials AUC1.73.34.41.7-2.1-1.8-1.61.9-1.8-1.8-1.7-1.9
Run reversals in cocaine runway, females1.71.73.0-1.50.61.11.7-1.41.41.21.31.0
Run reversals in cocaine runway, males0.40.40.70.8-0.5-0.7-0.60.6-0.7-0.6-0.6-0.6
Latency to leave start box in cocaine runway0.50.51.0-0.70.70.70.1-1.00.60.80.51.0
Latency to leave start box in cocaine runway, F0.20.20.4-0.60.50.50.1-0.60.20.40.30.6
Latency to leave start box in cocaine runway, M0.10.10.30.20.1-0.0-0.6-0.20.10.2-0.00.3
Std. dev. time between licks in bursts0.60.81.00.9-0.8-0.9-0.91.0-0.7-0.9-0.7-1.0
Total sessions with >9 infusions1.51.93.71.5-1.9-1.5-1.31.2-1.1-1.2-1.2-1.2
Short access day 1 total inactive lever presses1.72.23.01.6-1.6-1.6-1.71.1-1.6-1.5-1.6-1.0
Short access day 10 total inactive lever presses0.41.01.4-1.00.90.81.1-0.91.21.11.20.9
Short access day 1 total infusions1.01.32.61.1-1.6-1.1-1.01.2-1.1-1.1-1.1-0.9
Short access day 10 total infusions3.34.25.91.9-2.4-1.9-1.82.1-2.0-2.1-1.9-2.1
Short access total infusions1.72.24.01.3-2.0-1.4-1.31.5-1.5-1.6-1.4-1.4
Short access day 1 locomotion2.02.53.71.7-1.9-1.6-1.41.6-1.5-1.6-1.4-1.6
Short access day 10 total locomotion0.40.71.3-0.60.20.50.9-1.21.00.91.00.8
Short access total locomotion0.10.10.50.4-0.7-0.4-0.10.1-0.0-0.2-0.0-0.3
One hour access (0.3 mA shock)0.00.00.10.1-0.3-0.0-0.1-0.1-0.1-0.1-0.00.0
Compulsive drug intake0.10.10.20.4-0.3-0.5-0.40.2-0.2-0.2-0.2-0.3
One hour access (shock baseline)0.40.61.00.6-0.9-0.5-0.60.6-1.0-1.0-0.9-0.7
Social response proportion1.21.31.91.1-1.1-1.2-1.11.4-1.0-1.2-0.9-1.4
Social responses2.22.93.71.9-1.6-1.9-1.81.8-1.5-1.6-1.4-1.7
Social time0.20.31.00.11.00.2-0.0-0.50.40.60.20.6
Soleus weight0.41.11.41.1-0.9-1.0-1.01.1-1.0-1.2-1.1-1.1
Bone: stiffness1.21.93.31.8-1.2-1.6-1.61.3-1.1-1.1-1.4-1.2
Tibialis anterior weight2.89.712.03.0-3.0-3.0-2.93.5-2.8-3.4-2.8-3.4
Time to tail flick, vehicle, before self-admin0.10.10.50.0-0.7-0.20.1-0.00.2-0.10.2-0.3
Time to tail flick, vehicle, after self-admin0.10.20.5-0.40.70.50.2-0.30.30.40.30.3
Time to tail flick, test, before self-admin2.12.22.8-1.21.51.31.6-1.71.51.61.51.4
Time to tail flick, test, after self-admin0.10.10.3-0.40.60.40.3-0.40.20.20.10.2
Delta time to tail flick, vehicle, before/after SA0.10.10.6-0.10.80.4-0.1-0.1-0.10.2-0.10.2
Delta time to tail flick, test, before/after SA0.80.81.20.7-0.7-0.8-0.91.1-0.9-1.0-1.0-0.9
Tibia length1.44.06.82.6-1.7-2.4-2.31.6-2.1-1.5-2.0-1.5
Ambulatory time before self-admin0.00.10.20.30.2-0.3-0.1-0.10.20.50.20.0
Ambulatory time after self-admin0.70.81.2-0.71.00.50.8-0.81.11.11.10.8
Bone: tissue strength0.20.20.3-0.30.40.40.3-0.50.40.50.50.5
Total heroin consumption0.20.20.40.3-0.6-0.4-0.30.5-0.3-0.4-0.2-0.6
Bone: trabecular number0.10.20.3-0.40.50.40.5-0.40.50.50.40.5
Bone: trabecular spacing0.00.00.10.1-0.3-0.1-0.20.3-0.0-0.30.0-0.3
Bone: trabecular thickness0.40.50.90.7-0.8-0.7-0.70.6-0.8-0.6-0.9-0.5
Bone: trabecular tissue density0.10.20.4-0.0-0.6-0.1-0.10.5-0.3-0.6-0.2-0.5
Water consumed over 24 hours0.81.11.3-0.81.20.91.0-1.01.01.11.21.0
Number of responses in last shaping day2.02.23.21.3-1.8-1.2-1.41.5-1.6-1.7-1.6-1.2