Hub : Genes

Ehd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_039081636.1 0.06 0.05 8.9e-03 0.01 0.01 0.01 0.01 2.0e-02 2.9e-02 1.3e-02 8.7e-03
2 Adipose alternative TSS NM_001024897.1 0.06 0.05 8.5e-03 0.01 0.01 0.01 0.01 4.3e-02 4.7e-02 1.5e-02 1.3e-02
3 Adipose intron excision ratio chr1_76656052_76656522 0.08 0.05 1.1e-09 0.07 0.07 0.07 0.07 6.8e-08 1.5e-08 2.2e-08 4.1e-08
4 Adipose intron excision ratio chr1_76656052_76658721 0.12 0.07 1.4e-15 0.11 0.12 0.12 0.12 2.4e-12 3.7e-13 3.1e-13 4.6e-13
5 PL gene expression Ehd2 0.02 0.02 5.5e-03 0.02 0.01 0.01 0.02 3.6e-03 1.4e-02 8.6e-03 6.4e-03
6 NAcc gene expression Ehd2 0.04 0.03 4.4e-05 0.03 0.03 0.03 0.02 2.7e-04 3.1e-04 3.1e-04 7.8e-04
7 Adipose gene expression Ehd2 0.15 0.08 0.0e+00 0.19 0.18 0.17 0.18 4.1e-21 3.7e-20 8.7e-19 1.0e-19
8 Adipose mRNA stability Ehd2 0.65 0.46 0.0e+00 0.31 0.31 0.31 0.31 2.8e-35 1.1e-34 2.8e-35 1.7e-35
9 Brain gene expression Ehd2 0.1 0.07 4.8e-11 0.12 0.12 0.12 0.12 2.3e-11 7.2e-11 6.8e-11 8.3e-11
10 BLA gene expression Ehd2 0.14 0.11 6.1e-06 0.06 0.06 0.06 0.06 3.4e-04 2.5e-04 2.6e-04 2.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.40.61.3-0.10.1-0.7-0.8-0.9-0.9-0.90.9-0.91.1
Area under the delay curve0.70.72.31.5-1.5-0.8-0.6-0.6-0.6-0.20.6-0.60.3
BMI with tail0.82.64.1-0.10.11.51.52.01.91.9-1.81.8-1.9
BMI without tail1.73.65.3-0.10.11.91.92.32.32.2-2.22.0-2.1
Body weight1.25.27.2-1.71.62.62.42.72.62.4-2.32.3-2.1
Weight adjusted by age1.11.22.0-1.41.41.11.10.80.81.1-0.80.8-1.2
Bone surface0.61.15.0-2.22.20.60.5-0.1-0.10.0-0.30.20.2
Bone volume0.40.73.2-1.71.80.20.0-0.4-0.4-0.40.2-0.30.7
Breakpoint value in progressive ratio session3.23.57.02.7-2.6-2.2-1.9-1.6-1.6-1.21.6-1.61.2
Number of licking bursts2.02.42.9-0.80.71.61.71.71.71.7-1.71.7-1.7
Context. condit. distance diff. score0.10.10.2-0.40.40.30.20.30.30.2-0.10.20.1
Locomotion velocity, session 10.50.50.9-0.40.4-0.7-0.7-0.8-0.8-0.80.7-0.70.9
Locomotion distance, session 10.50.73.3-1.81.80.20.1-0.3-0.3-0.30.1-0.20.4
Locomotion velocity, session 21.11.31.8-1.31.31.21.11.01.01.1-1.21.1-1.1
Locomotion distance, session 21.41.95.1-2.32.31.41.30.90.90.9-1.01.0-0.9
Locomotion velocity, session 30.10.10.2-0.40.40.40.30.40.40.3-0.20.3-0.3
Locomotion distance, session 30.40.51.2-1.11.1-0.1-0.3-0.6-0.6-0.60.5-0.50.9
Stereotopy head waving bouts, day 30.20.30.50.7-0.70.20.30.60.60.5-0.40.4-0.6
Stereotopy head waving duration, day 30.20.21.01.0-1.0-0.1-0.10.30.30.1-0.00.1-0.3
Locomotion velocity, session 71.31.42.00.4-0.4-1.2-1.2-1.3-1.3-1.31.4-1.31.3
Locomotion distance, session 70.10.10.3-0.00.0-0.3-0.3-0.4-0.4-0.50.4-0.40.4
Stereotopy head waving bouts, day 70.20.20.5-0.70.70.50.40.40.40.5-0.40.4-0.3
Stereotopy head waving duration, day 70.30.40.5-0.60.60.70.60.60.60.7-0.50.6-0.6
Locomotion velocity, session 80.10.20.3-0.20.2-0.3-0.3-0.3-0.3-0.40.6-0.50.5
Locomotion distance, session 80.30.51.7-1.31.30.60.50.40.40.4-0.30.3-0.0
Degree of sensitization distance0.10.10.50.7-0.7-0.10.00.10.10.1-0.10.1-0.4
Degree of sensitization stereotypy1.21.32.0-1.41.41.21.11.01.01.1-1.01.0-0.8
Conditioned locomotion0.10.10.1-0.10.10.30.30.40.40.3-0.30.3-0.4
Cocaine response after cond. corrected0.30.41.51.2-1.2-0.10.10.30.30.4-0.20.2-0.6
Cocaine response after cond. not corrected0.50.61.2-0.40.40.80.90.70.70.8-0.80.8-1.1
Cocaine response before conditioning3.84.612.6-3.53.62.12.01.41.41.3-1.71.6-1.4
Saline control response1.11.43.2-1.81.81.21.20.90.90.9-1.01.0-0.9
Bone: connectivity density0.10.10.3-0.20.2-0.3-0.3-0.5-0.5-0.40.4-0.40.5
Bone: cortical apparent density0.10.20.90.9-0.9-0.4-0.3-0.1-0.1-0.10.0-0.10.0
Bone: cortical area0.61.01.9-1.41.41.11.00.80.80.8-0.90.9-0.6
Bone: cortical porosity0.20.20.90.9-1.0-0.2-0.20.00.0-0.1-0.20.10.1
Bone: cortical porosity0.20.30.60.3-0.40.40.30.60.60.5-0.80.6-0.4
Bone: cortical thickness0.10.20.90.9-1.0-0.2-0.20.00.00.0-0.0-0.00.1
Bone: cortical thickness0.20.20.6-0.60.60.50.40.40.40.3-0.80.6-0.2
Bone: cortical tissue density0.20.20.90.9-0.9-0.4-0.3-0.1-0.1-0.10.1-0.10.1
Condit. Reinf. active minus inactive responses0.70.81.20.1-0.10.80.91.01.01.1-0.90.9-1.1
Condit. Reinf. active-inactive response ratio0.91.01.50.4-0.50.80.91.21.21.2-1.01.0-1.2
Condit. Reinf. active responses0.40.50.8-0.40.40.70.80.70.70.8-0.60.7-0.9
Condit. Reinf. inactive responses0.40.41.2-1.11.1-0.1-0.1-0.7-0.7-0.40.5-0.50.4
Incentive salience index mean0.60.81.0-0.50.50.91.01.01.01.0-0.90.9-1.0
Condit. Reinf. lever presses0.30.40.7-0.80.80.70.70.50.50.6-0.60.6-0.6
Condit. Reinf. active minus inactive responses0.81.04.6-2.12.20.40.3-0.3-0.3-0.30.1-0.10.2
Condit. Reinf. active-inactive response ratio0.70.73.5-1.81.90.50.4-0.2-0.2-0.1-0.10.00.1
Condit. Reinf. active responses0.81.15.3-2.22.30.40.2-0.4-0.4-0.40.1-0.10.4
Condit. Reinf. inactive responses0.10.20.3-0.40.5-0.3-0.3-0.5-0.5-0.50.4-0.40.5
Condit. Reinf. lever presses0.70.91.4-1.21.21.11.00.80.80.8-0.80.9-0.9
Condit. Reinf. lever reinforcers received1.11.57.2-2.62.70.60.4-0.3-0.3-0.3-0.0-0.00.3
Conditioned reinforcement - actives1.11.11.60.6-0.71.00.91.31.31.2-1.21.2-1.0
Conditioned reinforcement - inactives1.61.82.9-1.71.71.41.50.90.91.5-1.21.1-1.2
Conditioned locomotion0.80.91.50.2-0.20.91.01.21.21.2-1.01.1-1.0
Patch foraging indifference point 0 sec0.10.10.20.5-0.5-0.00.10.20.20.50.0-0.1-0.3
Patch foraging indifference point AUC3.03.44.3-1.21.22.01.92.12.12.0-2.11.9-1.8
Delay disc. indifference point, 0s delay0.30.41.0-0.91.0-0.2-0.3-0.6-0.6-0.50.5-0.40.6
Delay disc. indifference point, 16s delay0.90.93.81.9-1.9-0.8-0.5-0.3-0.30.00.5-0.5-0.1
Delay disc. indifference point, 2s delay0.40.40.60.5-0.5-0.7-0.7-0.8-0.8-0.60.7-0.70.6
Delay disc. indifference point, 24s delay0.40.41.31.1-1.20.10.40.40.40.7-0.20.2-0.8
Delay disc. indifference point, 4s delay0.20.20.3-0.50.50.50.50.40.40.5-0.40.5-0.3
Delay disc. indifference point, 8s delay1.41.43.92.0-2.0-1.1-0.9-1.0-1.0-0.60.9-0.90.7
Indifference point function ln k2.23.15.0-0.40.5-1.6-1.5-2.2-2.2-1.92.1-2.01.9
Indifference point function log k2.23.15.0-0.40.5-1.6-1.5-2.2-2.2-1.92.1-2.01.9
Patch foraging total patch changes 0 sec0.10.10.30.5-0.50.00.10.40.30.6-0.10.1-0.4
Patch foraging total patch changes 12 sec1.41.82.6-0.60.61.41.41.61.51.6-1.51.5-1.5
Patch foraging total patch changes 18 sec1.31.72.7-0.80.81.31.21.61.61.4-1.51.5-1.1
Patch foraging total patch changes 24 sec1.82.12.8-1.21.31.61.41.71.61.5-1.51.6-1.2
Patch foraging total patch changes 6 sec1.11.62.5-0.20.21.21.21.61.51.6-1.41.4-1.4
Patch foraging time to switch 0 sec2.94.512.73.5-3.6-2.1-2.1-1.2-1.2-1.61.4-1.31.4
Patch foraging water rate 0 sec1.82.94.6-2.12.11.91.91.41.41.7-1.31.3-1.6
Patch foraging water rate 12 sec0.30.52.5-1.51.60.20.2-0.4-0.4-0.20.2-0.30.3
Patch foraging water rate 18 sec0.20.20.7-0.80.8-0.0-0.0-0.4-0.4-0.10.5-0.60.2
Patch foraging water rate 24 sec0.20.30.5-0.60.6-0.2-0.2-0.7-0.7-0.40.7-0.60.4
Patch foraging water rate 6 sec3.14.513.1-3.63.62.22.01.31.31.3-1.51.3-1.2
Seeking ratio, delayed vs. immediate footshock1.72.03.20.6-0.6-1.3-1.4-1.6-1.6-1.51.6-1.81.5
Distance traveled before self-admin0.40.42.0-1.41.40.40.40.00.00.10.10.0-0.0
Distance traveled after self-admin0.80.91.3-1.11.2-0.6-0.6-1.0-1.0-0.81.0-1.00.9
Extensor digitorum longus weight1.24.76.2-1.81.82.52.32.32.32.3-2.02.2-2.1
Bone: elastic displacement2.93.34.32.1-2.1-2.0-1.9-1.7-1.7-1.71.8-1.81.5
Bone: elastic work0.20.20.30.0-0.0-0.4-0.4-0.6-0.6-0.50.6-0.60.5
Bone: endosteal estimation0.71.57.2-2.62.70.80.6-0.0-0.00.1-0.20.20.1
Bone: endosteal perimeter0.51.04.6-2.12.10.70.60.00.00.2-0.30.3-0.0
Epididymis fat weight0.92.24.62.1-2.1-1.5-1.5-1.1-1.2-1.31.2-1.21.3
Delta time in closed arm before/after self-admin0.10.10.2-0.30.30.40.10.50.50.3-0.40.3-0.1
Delta time in open arm before/after self-admin0.40.31.7-1.21.30.30.40.00.00.1-0.10.0-0.2
Diff in mean of infusions in LGA sessions1.61.82.71.1-1.0-1.4-1.6-1.3-1.3-1.71.3-1.21.6
Delay discount exponential model param0.60.62.3-1.51.50.60.40.40.40.1-0.50.4-0.2
Extinction: sum of active levers before priming0.70.71.10.1-0.1-0.8-0.9-1.0-1.0-0.90.9-0.90.9
Active lever presses in extinction session 61.71.62.40.4-0.51.11.11.51.51.6-1.51.5-1.3
Bone: final force1.01.74.5-2.12.11.31.20.90.90.8-1.01.0-0.6
Bone: final moment1.32.06.0-2.42.51.41.30.90.90.8-1.01.0-0.6
Food consumed during 24 hour testing period2.63.15.00.8-0.8-1.8-1.9-1.9-1.9-1.91.9-1.92.2
Glucose1.92.83.81.7-1.7-1.7-1.7-1.6-1.6-1.61.6-2.01.5
Heart weight0.81.12.9-1.71.60.91.20.60.60.8-0.50.5-1.2
Delay discount hyperbolic model param0.30.31.1-1.01.10.50.30.30.3-0.0-0.40.3-0.1
Intermittent access intake day 1-15 change0.10.10.2-0.10.10.40.10.40.4-0.3-0.40.40.1
Intermittent access intake escalation0.10.10.20.2-0.20.2-0.10.30.3-0.4-0.30.30.2
Intermittent access intake escalation 20.00.00.10.0-0.10.2-0.00.20.2-0.3-0.10.20.3
Intermitt. access day 1 inactive lever presses0.70.81.90.1-0.00.81.00.70.71.3-0.90.8-1.4
Intermitt. access day 15 inactive lever presses2.83.14.3-1.11.12.01.91.81.81.9-2.12.0-1.8
Intermitt. access escalation Index0.60.52.41.5-1.5-0.0-0.10.40.40.0-0.40.5-0.2
Intermittent access day 1 total infusions0.91.11.7-1.31.31.11.10.90.90.9-1.00.9-0.9
Intermittent access day 15 total infusions0.20.20.50.3-0.30.50.30.60.60.1-0.70.7-0.3
Intermittent access terminal intake (last 3 days)0.10.10.20.2-0.20.40.20.40.4-0.0-0.40.4-0.1
Intermittent access total infusions0.50.50.8-0.30.30.90.80.80.80.7-0.90.8-0.7
Intermittent access day 1 locomotion0.20.20.40.3-0.2-0.4-0.2-0.6-0.6-0.30.5-0.60.3
Intermittent access day 15 total locomotion0.20.20.50.5-0.4-0.5-0.5-0.4-0.4-0.70.3-0.30.6
Intermittent access total locomotion0.00.00.0-0.00.10.10.2-0.0-0.0-0.0-0.0-0.00.0
Intermittent access standard deviation1.21.32.40.3-0.41.00.71.61.60.9-1.51.5-0.8
Left kidney weight7.621.328.0-5.35.25.14.94.44.44.2-4.34.2-4.1
Right kidney weight5.014.118.1-4.34.24.03.93.53.53.5-3.43.5-3.5
Cocaine induced anxiety1.71.93.4-0.60.6-1.2-0.9-1.8-1.8-1.31.8-1.81.2
Post-drug Anxiety0.20.20.5-0.70.7-0.3-0.1-0.5-0.5-0.20.5-0.50.0
Baseline Anxiety0.30.30.60.8-0.70.20.10.60.60.4-0.60.7-0.5
Tail length0.41.21.7-1.11.11.31.21.11.11.0-1.01.0-0.8
Length with tail0.62.15.3-2.32.21.71.41.21.21.0-1.01.0-0.7
Length without tail0.40.93.1-1.81.70.90.70.60.60.3-0.40.5-0.2
Times rat made contact with spout0.50.61.10.6-0.6-0.8-0.8-0.7-0.7-0.80.9-0.81.0
Lifetime Intake0.40.50.7-0.20.20.80.80.80.80.6-0.80.8-0.7
Liver weight, left10.817.221.1-2.82.74.44.44.64.64.4-4.64.3-4.2
Liver weight, right2.74.56.6-0.90.92.22.42.32.32.5-2.22.1-2.6
Locomotor activity1.42.23.3-0.70.71.51.61.61.51.8-1.51.6-1.8
Locomotor testing distance0.61.01.5-0.80.81.11.21.00.91.2-0.81.0-1.1
Locomotor testing rearing5.17.99.7-2.62.63.13.12.82.82.8-2.72.8-2.8
Locomotion in novel chamber2.93.65.41.6-1.4-2.3-2.0-2.0-2.0-1.72.1-2.11.6
Locomotion in novel chamber post-restriction0.91.01.31.0-1.0-1.1-1.2-0.8-0.8-1.11.1-1.01.1
Fecal boli incidents, locomotor time 10.10.10.40.2-0.2-0.3-0.4-0.4-0.4-0.50.3-0.30.6
Change in fecal boli incidents, locomotor task0.60.61.41.2-1.1-0.9-0.8-0.5-0.5-0.60.5-0.60.5
Time >=10cm from walls, locomotor time 10.20.20.30.6-0.5-0.5-0.4-0.4-0.4-0.40.3-0.30.2
Bouts of movement, locomotor time 11.11.21.91.0-0.9-1.0-1.1-1.2-1.2-1.21.0-1.01.4
Total resting periods, locomotor time 12.22.42.81.5-1.5-1.6-1.6-1.6-1.6-1.51.4-1.41.7
Rest time, locomotor task time 10.30.40.7-0.40.4-0.4-0.5-0.7-0.7-0.80.5-0.70.8
Distance moved, locomotor task time 10.50.51.5-0.0-0.10.60.80.70.71.2-0.60.7-1.0
Vertical activity count, locomotor time 10.10.10.30.4-0.40.00.20.20.20.5-0.10.2-0.5
Time >=10cm from walls, locomotor time 20.00.00.10.1-0.0-0.1-0.20.10.1-0.1-0.20.20.4
Bouts of movement, locomotor time 21.31.42.30.5-0.3-1.4-1.3-1.5-1.5-1.21.2-1.21.2
Total resting periods, locomotor time 21.92.03.10.6-0.4-1.6-1.5-1.7-1.7-1.41.5-1.51.4
Rest time, locomotor task time 21.51.72.50.3-0.2-1.3-1.4-1.5-1.5-1.61.4-1.51.4
Distance moved, locomotor task time 21.51.72.7-0.80.71.41.41.51.51.6-1.31.3-1.3
Vertical activity count, locomotor time 20.70.71.0-0.50.50.90.91.01.00.9-0.90.8-0.9
Light reinforcement 10.61.01.8-1.31.31.01.10.80.81.0-0.90.9-0.9
Light reinforcement 20.91.22.10.1-0.10.91.11.21.31.3-1.31.1-1.4
Bone: marrow area0.81.77.7-2.72.80.90.70.00.00.1-0.30.30.0
Bone: maximum diameter2.64.85.9-2.42.42.32.32.02.02.0-2.22.1-1.9
Bone: maximum force0.71.24.0-2.02.01.11.00.60.60.6-0.70.7-0.4
Bone: maximum moment0.91.55.3-2.32.31.21.00.60.60.6-0.70.7-0.3
Mean time between licks in bursts0.10.10.60.7-0.8-0.00.00.30.30.20.10.1-0.2
Mean num. licks in bursts3.54.15.81.1-1.0-2.1-2.2-2.1-2.1-2.22.2-2.22.4
Cd content in liver0.20.20.4-0.40.4-0.3-0.3-0.3-0.3-0.60.3-0.40.6
Co content in liver1.21.42.40.7-0.6-1.2-1.3-1.1-1.1-1.31.3-1.31.6
Cu content in liver0.50.61.4-1.21.20.80.70.70.70.6-0.60.6-0.5
Fe content in liver0.30.40.5-0.60.60.70.50.70.70.5-0.70.7-0.3
K content in liver1.61.61.9-1.31.21.41.31.31.31.1-1.31.3-1.1
Mg content in liver1.41.42.1-0.50.51.21.31.31.31.4-1.31.3-1.4
Mn content in liver1.01.11.7-0.10.11.11.01.31.31.1-1.31.2-1.2
Na content in liver0.20.20.70.8-0.8-0.2-0.30.20.20.00.2-0.10.2
Rb content in liver0.30.40.8-0.90.90.70.60.60.60.4-0.70.6-0.3
Se content in liver4.55.68.0-0.40.32.42.42.82.82.7-2.52.6-2.8
Sr content in liver0.60.52.51.5-1.6-0.3-0.10.20.20.3-0.20.2-0.4
Zn content in liver0.80.91.90.1-0.10.91.01.01.01.2-0.91.0-1.4
Bone: minimum diameter1.12.08.5-2.92.91.21.00.40.40.5-0.70.7-0.1
Time in familiar zone, hab. session 10.70.73.1-1.71.70.20.1-0.4-0.4-0.50.2-0.20.3
Time in novel zone, hab. session 11.21.21.80.6-0.70.90.91.31.31.4-1.11.2-1.2
Total zone transitions, hab. session 10.50.73.4-1.81.80.40.3-0.1-0.1-0.1-0.20.10.2
Total locomotion distance, hab. session 10.40.61.0-0.60.6-0.5-0.6-0.8-0.8-0.90.8-0.81.0
Locomotion velocity, hab. session 10.91.32.1-0.00.1-1.1-1.2-1.3-1.3-1.31.3-1.31.5
Time in familiar zone, hab. session 20.20.20.5-0.70.7-0.1-0.1-0.5-0.5-0.50.2-0.30.2
Time in novel zone, hab. session 20.30.30.50.4-0.40.40.40.70.70.7-0.60.6-0.3
Total zone transitions, hab. session 21.31.66.2-2.52.51.11.00.50.50.5-0.80.7-0.5
Total locomotion distance, hab. session 20.40.51.1-0.20.2-0.7-0.8-0.7-0.7-1.00.7-0.81.0
Locomotion velocity, hab. session 20.20.30.7-0.30.3-0.5-0.6-0.5-0.5-0.80.6-0.60.8
Novel to familiar place preference ratio0.60.70.8-0.70.70.90.90.90.90.9-0.70.8-0.8
Novelty place preference0.60.60.8-0.90.90.90.80.70.70.7-0.60.7-0.7
Time in novel zone, NPP test0.60.60.8-0.90.90.90.80.80.80.8-0.60.7-0.7
Total zone transitions, NPP test0.30.41.0-1.01.00.60.60.40.40.6-0.50.5-0.4
Total locomotion distance, NPP test0.00.10.2-0.40.40.20.20.30.30.1-0.20.20.0
Locomotion velocity, NPP test0.10.10.4-0.60.60.30.20.30.30.1-0.30.20.0
Intraocular pressure0.20.20.5-0.40.5-0.3-0.5-0.5-0.4-0.60.5-0.40.7
Delta distance traveled before/after self-admin0.50.60.80.5-0.4-0.8-0.9-0.8-0.8-0.80.7-0.80.8
Delta ambulatory time before/after self-admin0.60.70.90.8-0.7-0.9-1.0-0.9-0.9-0.90.7-0.80.8
Parametrial fat weight1.22.410.43.2-3.2-1.2-0.9-0.3-0.30.10.7-0.60.1
Pavlov. Cond. lever latency0.60.81.10.7-0.7-0.9-1.0-0.9-0.9-1.10.8-0.91.0
Pavlov. Cond. magazine entry latency1.01.21.9-0.20.11.11.21.31.31.4-1.21.2-1.4
Pavlov. Cond. change in total contacts0.00.00.10.4-0.4-0.1-0.0-0.0-0.00.10.2-0.1-0.1
Pavlov. Cond. index score1.21.52.1-0.50.41.21.31.41.41.5-1.31.3-1.4
Pavlov. Cond. latency score0.60.71.2-0.20.10.80.91.01.01.1-0.90.9-1.1
Pavlov. Cond. lever contacts0.91.11.6-0.60.61.11.11.21.21.2-1.01.1-1.2
Pavlov. Cond. magazine entry number0.70.91.30.5-0.4-1.0-1.0-1.1-1.1-1.11.0-1.01.0
Pavlov. Cond. intertrial magazine entries0.30.40.7-0.00.1-0.6-0.6-0.7-0.7-0.80.8-0.80.6
Pavlov. Cond. lever-magazine prob. diff.1.41.72.5-0.50.41.31.41.51.51.6-1.41.4-1.5
Pavlov. Cond. response bias2.83.44.3-1.11.01.92.02.02.02.1-2.02.0-2.0
Pavlov. Cond. lever latency0.10.20.2-0.20.2-0.3-0.3-0.4-0.4-0.50.4-0.50.5
Pavlov. Cond. magazine entry latency0.20.20.90.9-0.9-0.1-0.00.20.20.1-0.20.2-0.2
Pavlov. Cond. change in total contacts0.20.30.4-0.40.5-0.4-0.4-0.7-0.7-0.60.5-0.50.6
Pavlov. Cond. index score0.00.10.10.1-0.10.20.20.30.30.2-0.30.3-0.3
Pavlov. Cond. latency score0.10.10.40.6-0.6-0.1-0.10.00.0-0.0-0.00.0-0.0
Pavlov. Cond. lever contacts0.30.50.6-0.60.60.80.70.70.70.7-0.70.7-0.7
Pavlov. Cond. magazine entry number0.20.30.6-0.80.80.50.50.40.40.5-0.40.4-0.4
Pavlov. Cond. intertrial magazine entries0.81.04.9-2.22.20.50.4-0.1-0.1-0.00.2-0.10.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.10.10.40.30.40.40.3-0.40.4-0.4
Pavlov. Cond. response bias0.20.30.8-0.90.90.60.50.40.40.4-0.50.5-0.4
Time in closed arm before self-admin0.20.20.5-0.20.20.40.50.40.40.4-0.60.7-0.6
Time in closed arm after self-admin0.10.10.40.6-0.60.1-0.00.20.20.3-0.30.4-0.3
Time in open arm before self-admin0.10.10.5-0.10.1-0.3-0.2-0.3-0.3-0.00.5-0.70.2
Time in open arm after self-admin0.20.31.2-1.01.1-0.00.1-0.3-0.3-0.10.3-0.40.1
Bone: periosteal estimation0.91.87.0-2.62.61.21.10.50.50.6-0.70.7-0.4
Bone: periosteal perimeter0.91.56.1-2.42.51.00.90.30.30.4-0.60.6-0.2
Bone: post-yield work0.30.41.9-1.31.40.30.2-0.2-0.2-0.1-0.10.10.3
Progressive ratio test 1 active lever presses0.60.72.9-1.61.70.60.60.10.10.2-0.30.10.0
Progressive ratio test 1 breakpoint0.40.52.1-1.41.40.50.60.10.10.1-0.20.00.1
Progressive ratio test 1 inactive lever presses2.52.75.4-2.32.31.81.81.21.21.4-1.41.1-1.3
Progressive ratio test 2 active lever presses0.30.30.5-0.20.20.70.70.60.60.6-0.70.6-0.6
Progressive ratio test 2 breakpoint0.30.30.5-0.30.30.70.70.60.60.6-0.70.6-0.6
Progressive ratio test 2 inactive lever presses1.11.22.2-1.41.51.21.10.90.90.8-1.11.0-0.8
Incentive Sensitization - Responses0.30.30.4-0.30.30.60.60.50.50.5-0.70.5-0.6
Incentive Sensitization - Breakpoint0.30.30.5-0.10.10.60.60.60.60.5-0.70.6-0.7
Sum of active levers in priming session hrs 5-61.71.72.41.5-1.4-1.5-1.4-1.2-1.2-1.11.3-1.21.0
Progressive ratio0.20.20.50.5-0.5-0.3-0.4-0.3-0.3-0.70.4-0.40.6
Food seeking constrained by brief footshock3.03.75.20.4-0.3-1.8-1.8-2.3-2.3-2.32.2-2.22.2
Seeking ratio, punishment vs. effort0.70.81.4-0.10.2-0.9-0.9-1.2-1.2-1.01.0-1.01.0
Retroperitoneal fat weight1.34.418.04.2-4.2-1.7-1.5-0.4-0.5-0.61.0-1.20.6
Reaction time number correct1.72.42.9-1.21.21.61.61.71.71.6-1.61.5-1.7
Reaction time mean minus median0.50.61.10.1-0.0-0.9-1.0-0.8-0.7-1.10.8-0.71.0
Reaction time mean minus median AUC0.10.10.3-0.30.3-0.2-0.4-0.2-0.1-0.50.3-0.10.5
Reaction time num false alarms4.76.38.2-1.71.72.62.62.92.82.7-2.72.5-2.7
Reaction time num false alarms AUC3.65.06.8-1.61.52.32.32.62.62.4-2.42.1-2.4
Reaction time trials correct on left1.72.42.9-1.21.21.61.61.71.71.6-1.61.5-1.7
Reaction time trials on left1.72.53.0-1.21.21.61.61.71.71.6-1.71.5-1.7
Reaction time mean1.21.62.40.8-0.8-1.5-1.3-1.4-1.3-1.31.5-1.41.2
Reaction time mean AUC1.21.62.21.3-1.3-1.5-1.3-1.3-1.2-1.11.5-1.31.0
Median of all reaction times1.01.42.01.0-1.0-1.3-1.2-1.3-1.2-1.11.4-1.20.9
Reaction time omissions0.30.40.8-0.50.50.40.60.50.60.9-0.60.6-0.9
Reaction time false alarm rate0.60.81.3-0.50.50.90.91.11.11.0-0.90.8-1.0
Reaction time premature initiation rate1.92.63.01.5-1.4-1.7-1.6-1.7-1.7-1.71.7-1.61.5
Reaction time premature initiations0.50.70.90.9-0.9-0.9-0.8-0.8-0.7-0.80.8-0.90.6
Std. dev. reaction times0.60.91.40.3-0.3-1.1-1.1-1.0-0.9-1.11.2-1.11.0
Reaction time trials completed1.72.53.0-1.21.21.61.61.71.71.6-1.71.5-1.7
Reaction time trials AUC2.23.13.9-1.31.21.81.91.91.91.9-1.91.7-2.0
Run reversals in cocaine runway, females1.01.01.80.8-0.9-1.3-1.0-1.0-1.0-1.01.1-0.90.9
Run reversals in cocaine runway, males1.00.91.5-1.21.21.00.90.90.90.8-0.90.8-0.8
Latency to leave start box in cocaine runway0.50.51.1-0.10.0-0.6-0.8-0.8-0.8-0.90.6-0.61.1
Latency to leave start box in cocaine runway, F0.20.30.7-0.30.3-0.4-0.5-0.5-0.5-0.60.5-0.50.8
Latency to leave start box in cocaine runway, M0.20.20.4-0.60.60.40.30.30.30.1-0.40.4-0.1
Std. dev. time between licks in bursts0.70.91.1-0.90.91.01.01.01.00.9-0.90.9-1.0
Total sessions with >9 infusions1.82.03.0-1.00.91.71.71.41.41.5-1.51.4-1.5
Short access day 1 total inactive lever presses1.51.72.2-1.41.51.31.31.31.30.9-1.51.4-1.1
Short access day 10 total inactive lever presses0.40.50.70.7-0.7-0.8-0.6-0.9-0.9-0.30.7-0.70.5
Short access day 1 total infusions0.20.20.4-0.40.50.60.60.40.40.4-0.50.4-0.5
Short access day 10 total infusions2.22.43.2-1.21.21.61.51.71.71.5-1.81.7-1.5
Short access total infusions0.20.30.40.1-0.00.50.50.60.60.5-0.60.6-0.6
Short access day 1 locomotion0.20.30.6-0.40.40.50.70.30.30.7-0.40.3-0.6
Short access day 10 total locomotion1.01.11.61.0-0.9-1.0-0.8-1.1-1.1-1.01.1-1.31.0
Short access total locomotion0.20.20.50.7-0.6-0.4-0.3-0.4-0.4-0.20.4-0.50.3
One hour access (0.3 mA shock)0.00.10.10.00.1-0.1-0.2-0.3-0.3-0.40.1-0.10.4
Compulsive drug intake0.10.10.3-0.00.1-0.1-0.1-0.5-0.5-0.30.3-0.50.1
One hour access (shock baseline)0.91.01.9-0.30.21.00.91.31.30.9-1.31.4-0.7
Social response proportion1.11.11.8-0.70.71.11.21.01.11.3-1.01.0-1.3
Social responses2.93.77.4-2.72.71.91.91.51.51.6-1.61.4-1.7
Social time0.81.14.2-2.02.1-0.0-0.3-0.6-0.6-0.80.3-0.40.9
Soleus weight0.20.61.1-0.20.20.90.90.80.81.1-0.70.8-1.0
Bone: stiffness1.82.85.4-2.32.31.81.71.41.41.4-1.41.5-1.2
Tibialis anterior weight2.17.111.1-0.20.12.72.73.13.13.3-2.72.9-3.1
Time to tail flick, vehicle, before self-admin0.20.20.30.5-0.5-0.10.2-0.5-0.50.10.2-0.3-0.6
Time to tail flick, vehicle, after self-admin0.30.30.90.9-0.9-0.4-0.5-0.2-0.2-0.40.3-0.20.5
Time to tail flick, test, before self-admin2.01.92.8-0.40.4-1.2-1.2-1.7-1.7-1.51.7-1.71.6
Time to tail flick, test, after self-admin0.10.10.2-0.20.20.10.10.20.20.4-0.20.40.1
Delta time to tail flick, vehicle, before/after SA0.20.20.40.3-0.40.1-0.30.60.6-0.0-0.30.30.5
Delta time to tail flick, test, before/after SA0.90.81.50.3-0.30.60.81.01.01.2-1.01.2-1.1
Tibia length2.67.218.2-4.34.32.72.61.81.81.8-2.12.1-1.9
Ambulatory time before self-admin0.20.21.0-1.01.00.20.2-0.3-0.3-0.10.3-0.10.2
Ambulatory time after self-admin1.31.52.0-1.01.0-1.0-1.0-1.4-1.4-1.31.3-1.41.2
Bone: tissue strength0.10.10.20.2-0.2-0.2-0.2-0.2-0.2-0.20.4-0.30.3
Total heroin consumption0.20.31.21.1-1.1-0.3-0.1-0.0-0.00.30.1-0.1-0.3
Bone: trabecular number0.40.61.30.1-0.1-0.7-0.8-0.9-0.9-0.90.8-0.81.1
Bone: trabecular spacing0.20.20.6-0.20.20.50.50.60.60.6-0.30.4-0.8
Bone: trabecular thickness0.10.20.3-0.30.30.40.30.50.50.3-0.50.5-0.2
Bone: trabecular tissue density0.60.92.21.4-1.50.20.40.90.90.9-0.80.7-1.0
Water consumed over 24 hours0.40.51.0-0.40.5-0.5-0.6-0.7-0.7-0.80.8-0.81.0
Number of responses in last shaping day0.60.71.20.7-0.80.70.80.90.90.7-0.91.1-0.6