Hub : Genes

Eftud2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg intron excision ratio chr10_88333290_88334984 0.25 0.1 3.9e-06 0.13 0.11 0.15 0.12 3.0e-04 7.6e-04 8.6e-05 3.7e-04
2 RMTg intron excision ratio chr10_88332934_88334984 0.26 0.1 1.4e-06 0.13 0.13 0.18 0.15 2.2e-04 2.4e-04 1.4e-05 8.7e-05
3 Liver gene expression Eftud2 0.12 0.07 1.2e-07 0.02 0.05 0.02 0.04 1.4e-03 3.3e-06 1.2e-03 8.1e-05
4 NAcc mRNA stability Eftud2 0.25 0.08 0.0e+00 0.24 0.24 0.24 0.24 3.3e-36 2.4e-35 5.8e-36 2.4e-36
5 IC mRNA stability Eftud2 0.3 0.1 4.7e-09 0.24 0.18 0.22 0.23 2.0e-10 4.2e-08 1.5e-09 7.1e-10
6 OFC mRNA stability Eftud2 0.24 0.13 6.8e-03 0 0.04 0.02 0.02 3.3e-01 4.2e-02 1.1e-01 9.1e-02
7 pVTA intron excision ratio chr10_88333290_88334984 0.38 0.1 0.0e+00 0.39 0.41 0.42 0.41 3.5e-33 1.3e-35 2.4e-36 7.3e-35
8 Adipose gene expression Eftud2 0.23 0.07 0.0e+00 0.14 0.17 0.17 0.18 9.5e-15 3.6e-18 4.2e-18 5.0e-20
9 pVTA intron excision ratio chr10_88332934_88334984 0.41 0.1 0.0e+00 0.41 0.43 0.43 0.42 1.6e-35 1.6e-37 7.8e-38 9.9e-37
10 pVTA mRNA stability Eftud2 0.18 0.09 3.4e-10 0.06 0.12 0.12 0.11 1.3e-05 3.6e-10 7.1e-10 3.5e-09
11 Brain mRNA stability Eftud2 0.42 0.11 0.0e+00 0.31 0.35 0.33 0.33 1.6e-29 3.3e-34 1.5e-31 1.4e-31
12 Brain gene expression Eftud2 0.27 0.09 5.6e-17 0.11 0.2 0.2 0.2 1.4e-10 1.8e-18 1.1e-18 2.8e-18
13 BLA mRNA stability Eftud2 0.19 0.1 2.8e-06 0.08 0.11 0.09 0.1 3.1e-05 1.3e-06 1.6e-05 5.8e-06
14 LHb gene expression Eftud2 0.51 0.19 6.4e-06 0.2 0.05 0.25 0.21 1.6e-05 2.5e-02 1.3e-06 1.2e-05
15 pVTA gene expression Eftud2 0.16 0.07 2.8e-13 0.17 0.18 0.17 0.19 1.9e-13 2.9e-14 5.9e-14 7.7e-15
16 LHb mRNA stability Eftud2 0.24 0.15 5.4e-03 0.11 0.08 0.1 0.1 1.7e-03 6.3e-03 2.3e-03 2.6e-03
17 PL mRNA stability Eftud2 0.22 0.08 0.0e+00 0.18 0.18 0.18 0.18 2.0e-19 4.8e-19 1.6e-19 3.8e-19
18 Eye gene expression Eftud2 0.58 0.17 9.7e-05 0.17 0.26 0.37 0.32 1.5e-03 6.9e-05 9.0e-07 8.8e-06
19 NAcc gene expression Eftud2 0.16 0.05 0.0e+00 0.15 0.16 0.16 0.16 5.8e-22 3.6e-23 9.7e-23 4.7e-23
20 IC gene expression Eftud2 0.3 0.1 1.9e-11 0.21 0.27 0.23 0.27 3.0e-09 8.3e-12 3.7e-10 1.3e-11
21 IL gene expression Eftud2 0.36 0.16 2.1e-04 0.23 0.14 0.21 0.22 2.5e-06 3.1e-04 9.4e-06 6.1e-06
22 Adipose mRNA stability Eftud2 0.07 0.04 1.5e-06 0.06 0.05 0.03 0.06 2.9e-07 4.3e-06 9.8e-05 1.0e-06
23 IL mRNA stability Eftud2 0.41 0.13 1.0e-05 0.12 0.22 0.21 0.2 9.6e-04 6.7e-06 8.8e-06 1.9e-05
24 Liver mRNA stability Eftud2 0.06 0.04 5.1e-04 0 0.02 0.01 0.01 1.0e-01 1.6e-03 5.5e-02 2.7e-02
25 PL gene expression Eftud2 0.27 0.09 0.0e+00 0.17 0.21 0.19 0.2 7.4e-18 3.9e-22 1.0e-20 6.1e-22
26 BLA gene expression Eftud2 0.29 0.11 3.2e-09 0.09 0.16 0.16 0.16 1.3e-05 4.3e-09 1.3e-08 1.0e-08
27 OFC gene expression Eftud2 0.37 0.15 8.9e-04 0.28 0.16 0.18 0.22 2.1e-07 1.7e-04 3.7e-05 7.6e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density1.32.25.3-2.02.2-1.5-0.00.2-0.1-2.1-0.32.10.8-0.6-1.10.3-2.1-1.8-2.10.20.6-1.1-1.7-1.9-1.9-1.2-0.8-1.8-1.1-2.3
Area under the delay curve0.10.20.80.0-0.1-0.00.40.30.60.4-0.2-0.40.10.60.60.10.30.20.00.10.30.40.40.30.30.50.30.50.30.9
BMI with tail1.55.210.02.2-2.2-0.72.12.3-0.92.5-2.2-2.60.31.92.82.12.43.12.21.71.92.83.22.82.92.62.52.52.7-0.0
BMI without tail1.44.49.00.4-0.4-2.12.73.0-0.11.2-3.0-1.21.42.52.72.91.21.91.12.52.32.72.51.71.82.52.72.02.7-0.6
Body weight2.19.121.10.2-0.2-3.94.04.6-0.61.0-4.5-1.12.63.34.04.41.02.41.83.82.83.73.32.22.23.44.02.73.8-1.2
Weight adjusted by age0.30.53.1-0.20.0-0.70.80.71.1-0.1-0.60.21.01.00.90.3-0.0-0.10.30.9-0.30.70.70.20.20.80.80.80.61.8
Bone surface2.34.210.0-3.13.2-2.91.61.71.8-2.9-1.72.92.40.8-0.11.4-3.0-2.5-2.61.61.9-0.0-1.2-2.5-2.5-0.20.0-1.5-0.7-1.7
Bone volume1.62.87.3-2.52.7-2.20.91.11.1-2.4-1.12.41.60.3-0.40.9-2.5-2.1-2.50.91.5-0.4-1.3-2.1-2.1-0.6-0.4-1.6-0.9-1.8
Breakpoint value in progressive ratio session0.40.53.6-1.11.0-0.40.60.31.9-0.7-0.30.71.00.70.10.2-0.8-1.0-0.80.40.50.2-0.2-0.7-0.70.30.20.0-0.01.1
Number of licking bursts1.01.63.70.7-0.8-0.91.31.4-0.20.7-1.4-0.71.01.31.51.60.71.31.81.60.01.51.51.21.21.61.81.61.9-0.1
Context. condit. distance diff. score1.31.63.91.8-1.80.6-0.2-0.1-1.51.80.2-1.8-0.90.31.1-0.22.01.91.7-0.2-0.20.51.31.91.90.60.71.31.01.0
Locomotion velocity, session 10.40.40.9-0.10.20.2-0.4-0.7-0.2-0.40.70.5-0.4-0.9-0.6-0.8-0.5-0.6-0.7-0.7-0.5-0.8-0.7-0.6-0.6-0.9-0.9-0.9-1.0-0.4
Locomotion distance, session 10.30.31.00.3-0.10.6-0.6-0.7-0.40.00.80.0-0.7-0.9-0.5-0.8-0.0-0.1-0.7-1.00.3-0.7-0.5-0.1-0.1-0.8-0.8-0.7-0.9-0.3
Locomotion velocity, session 21.82.14.3-0.40.41.1-1.7-2.0-0.6-0.92.00.9-1.2-1.9-1.8-2.1-0.5-1.2-1.2-1.9-0.6-1.9-1.7-1.1-1.1-1.9-2.0-1.6-2.0-0.3
Locomotion distance, session 20.70.91.9-0.10.20.8-0.9-1.2-0.3-0.61.20.6-0.8-1.4-1.3-1.1-0.4-0.7-0.9-1.4-0.2-1.1-1.1-0.8-0.8-1.2-1.3-1.2-1.4-0.6
Locomotion velocity, session 30.10.10.90.3-0.1-0.2-0.2-0.1-1.0-0.10.10.1-0.3-0.6-0.1-0.2-0.10.0-0.2-0.10.6-0.4-0.20.00.0-0.5-0.3-0.4-0.3-0.7
Locomotion distance, session 30.30.32.80.2-0.2-0.30.30.5-0.30.2-0.4-0.20.20.30.60.40.30.60.60.61.70.50.50.60.60.40.60.70.60.5
Stereotopy head waving bouts, day 31.01.12.70.6-0.51.3-1.3-1.2-0.70.51.3-0.4-1.6-1.5-1.0-1.60.1-0.2-0.9-1.6-0.1-1.2-0.8-0.2-0.2-1.3-1.6-1.2-1.5-0.4
Stereotopy head waving duration, day 30.70.82.00.8-0.71.4-1.1-1.2-0.30.71.2-0.7-1.4-1.0-0.7-1.40.3-0.0-0.5-1.4-0.8-0.9-0.40.10.1-0.9-1.2-0.7-1.10.2
Locomotion velocity, session 70.70.73.71.2-1.00.9-1.0-0.7-1.90.90.8-0.9-1.3-1.0-0.5-0.80.90.70.7-0.9-0.6-0.6-0.10.70.7-0.6-0.5-0.2-0.2-0.6
Locomotion distance, session 70.30.41.20.7-0.70.8-0.7-0.6-1.10.50.8-0.6-1.0-0.6-0.4-0.90.90.40.5-0.8-0.0-0.5-0.10.60.6-0.4-0.40.2-0.20.5
Stereotopy head waving bouts, day 70.80.91.7-0.60.60.1-0.9-1.0-0.2-1.00.81.00.0-1.0-1.2-0.7-1.2-1.2-0.4-0.5-0.8-1.1-1.2-1.3-1.3-1.0-1.0-1.3-1.0-0.9
Stereotopy head waving duration, day 71.01.22.7-0.10.10.9-1.5-1.6-0.4-0.61.40.6-0.6-1.5-1.5-1.2-0.9-1.0-0.1-1.1-1.3-1.4-1.3-1.1-1.1-1.3-1.4-1.4-1.3-0.9
Locomotion velocity, session 80.50.62.01.4-1.20.40.20.2-1.21.4-0.2-1.3-0.8-0.40.6-0.01.11.30.4-0.30.50.40.91.01.00.20.10.10.2-0.9
Locomotion distance, session 80.60.92.11.2-1.11.4-1.1-1.1-1.10.91.3-0.8-1.5-1.0-0.4-1.31.10.70.3-1.4-0.5-0.7-0.10.70.7-0.7-0.8-0.1-0.60.5
Degree of sensitization distance0.10.10.70.4-0.4-0.00.20.1-0.40.50.0-0.5-0.20.10.2-0.10.60.30.1-0.1-0.80.10.30.40.40.10.10.20.20.2
Degree of sensitization stereotypy0.50.61.1-0.40.4-0.0-0.8-0.9-0.4-1.00.70.90.2-0.9-1.0-0.4-0.9-1.00.3-0.3-1.0-0.9-1.0-1.0-1.0-0.8-0.7-0.9-0.6-0.7
Conditioned locomotion0.00.10.9-0.20.2-0.2-0.10.0-0.4-0.1-0.10.1-0.1-0.00.20.00.10.2-0.20.00.9-0.1-0.10.10.1-0.10.00.10.20.1
Cocaine response after cond. corrected0.20.22.0-0.20.4-0.8-0.10.2-1.4-0.4-0.20.30.1-0.20.10.4-0.10.20.20.30.7-0.1-0.20.00.0-0.20.2-0.10.3-0.9
Cocaine response after cond. not corrected0.60.73.0-0.81.0-1.0-0.5-0.1-1.7-1.30.21.20.2-0.9-0.70.2-0.9-0.6-0.30.10.2-0.8-1.1-0.8-0.9-0.9-0.4-0.9-0.3-1.6
Cocaine response before conditioning0.91.02.0-0.70.70.0-0.8-0.6-0.1-1.30.71.3-0.0-1.2-1.4-0.6-1.2-1.4-0.9-0.5-0.9-1.0-1.3-1.4-1.4-1.1-1.1-1.3-1.1-0.9
Saline control response0.40.53.2-0.80.7-0.60.90.90.8-0.2-0.90.20.60.80.41.0-0.2-0.0-0.50.81.80.90.40.00.00.70.60.40.6-0.0
Bone: connectivity density2.03.17.5-2.72.7-1.90.30.40.9-2.7-0.42.71.5-0.2-1.00.4-2.7-2.4-2.30.50.3-1.0-1.8-2.4-2.4-1.1-0.8-1.8-1.2-1.8
Bone: cortical apparent density4.46.014.31.0-0.83.6-3.7-3.8-1.50.23.7-0.2-3.2-3.3-3.3-3.20.3-0.6-0.7-3.6-2.2-2.9-2.3-0.6-0.6-2.8-3.0-2.0-2.7-0.1
Bone: cortical area1.11.74.2-1.82.0-1.20.50.50.7-1.7-0.51.80.9-0.1-0.80.6-2.1-1.7-1.90.51.2-0.5-1.3-1.8-1.8-0.8-0.6-1.5-1.1-1.9
Bone: cortical porosity5.45.816.8-3.53.5-4.12.82.72.4-2.9-2.72.93.52.21.22.6-2.9-2.1-2.22.82.31.1-0.3-2.0-2.00.91.3-0.50.4-1.4
Bone: cortical porosity3.74.013.6-2.42.4-3.72.82.71.3-1.8-2.71.82.92.11.52.6-1.8-1.1-1.42.62.51.40.4-1.0-1.01.11.50.00.9-1.6
Bone: cortical thickness1.83.08.1-0.30.60.8-2.1-1.8-2.3-1.01.71.0-1.4-2.4-2.5-1.2-0.9-1.0-0.8-1.6-1.1-2.3-2.2-1.3-1.3-2.5-2.0-2.2-1.9-2.8
Bone: cortical thickness2.93.46.9-1.41.50.2-1.9-1.5-1.0-2.21.62.1-0.5-2.0-2.6-1.4-1.6-2.1-1.2-1.3-1.6-2.5-2.6-2.0-2.0-2.5-2.0-2.1-2.1-1.7
Bone: cortical tissue density4.35.914.10.9-0.83.6-3.6-3.8-1.40.23.6-0.2-3.1-3.2-3.3-3.20.2-0.6-0.7-3.5-2.2-2.8-2.3-0.6-0.6-2.8-3.0-2.0-2.7-0.0
Condit. Reinf. active minus inactive responses0.91.03.6-1.51.3-1.00.90.81.9-1.3-0.81.21.51.20.50.8-0.8-0.9-0.61.21.10.6-0.0-0.7-0.70.70.70.50.41.4
Condit. Reinf. active-inactive response ratio0.40.43.7-0.80.6-0.30.30.21.4-0.8-0.20.80.80.70.40.1-0.3-0.5-0.10.70.30.30.0-0.3-0.30.50.40.60.21.9
Condit. Reinf. active responses0.70.92.7-1.71.6-0.70.50.51.5-1.4-0.41.30.90.7-0.10.4-0.9-1.1-1.30.71.50.1-0.5-0.9-0.90.20.1-0.1-0.21.1
Condit. Reinf. inactive responses0.60.73.0-0.91.1-0.1-0.3-0.1-0.3-0.70.20.7-0.4-0.6-0.9-0.2-0.8-0.8-1.7-0.71.1-0.8-1.0-0.8-0.8-1.0-0.9-1.3-1.1-1.1
Incentive salience index mean0.91.13.3-1.81.6-1.00.60.61.8-1.6-0.51.61.40.80.00.6-1.3-1.3-0.91.01.20.3-0.4-1.1-1.10.30.3-0.00.01.0
Condit. Reinf. lever presses0.40.51.7-1.11.1-0.1-0.3-0.30.4-1.10.31.10.3-0.3-0.80.0-0.9-1.0-1.00.01.3-0.4-0.9-1.0-1.0-0.5-0.5-0.8-0.6-0.2
Condit. Reinf. active minus inactive responses2.53.39.8-3.13.0-1.90.60.41.9-2.9-0.52.91.70.2-0.70.2-2.5-2.8-2.70.61.2-0.8-1.7-2.4-2.4-0.8-0.6-1.3-1.10.0
Condit. Reinf. active-inactive response ratio2.22.68.1-2.82.6-1.91.00.72.2-2.4-0.82.52.10.7-0.30.6-2.3-2.3-1.81.21.3-0.1-1.0-2.0-2.0-0.10.0-0.7-0.40.3
Condit. Reinf. active responses2.63.710.5-3.23.2-1.80.60.22.3-3.0-0.33.01.70.2-0.80.0-2.7-3.0-2.80.40.9-0.9-1.8-2.6-2.6-0.9-0.7-1.5-1.40.1
Condit. Reinf. inactive responses1.01.33.3-1.01.10.2-0.8-0.90.6-1.30.81.2-0.3-0.8-1.3-1.0-1.2-1.5-1.8-1.1-0.2-1.2-1.5-1.3-1.4-1.2-1.3-1.5-1.6-0.3
Condit. Reinf. lever presses1.01.43.8-2.01.9-0.6-0.0-0.21.6-1.70.21.70.70.0-0.9-0.2-1.6-2.0-1.9-0.2-0.0-0.7-1.4-1.6-1.6-0.7-0.7-1.0-1.10.2
Condit. Reinf. lever reinforcers received2.33.29.0-3.02.9-1.50.40.12.1-2.8-0.22.81.40.1-0.9-0.1-2.5-2.8-2.80.20.8-0.9-1.8-2.4-2.4-0.9-0.8-1.4-1.40.2
Conditioned reinforcement - actives0.20.41.2-0.10.1-0.40.70.60.70.3-0.5-0.40.40.90.70.90.20.20.10.51.10.80.50.30.30.80.80.70.70.4
Conditioned reinforcement - inactives0.50.83.4-0.90.9-1.31.11.10.5-0.5-1.20.51.10.70.51.5-0.8-0.3-0.61.01.80.90.2-0.4-0.40.70.7-0.10.5-1.1
Conditioned locomotion1.31.73.9-0.60.5-1.61.72.01.3-0.1-1.70.01.51.81.71.90.00.20.31.61.31.61.10.40.41.61.81.41.50.8
Patch foraging indifference point 0 sec1.12.06.0-1.51.8-0.3-0.8-0.5-0.5-1.40.51.4-0.5-1.1-1.6-0.5-1.3-1.6-2.4-0.90.4-1.7-2.0-1.7-1.6-1.8-1.4-2.0-1.7-1.9
Patch foraging indifference point AUC0.40.61.9-0.60.5-1.41.00.70.0-0.4-0.80.31.21.11.01.3-0.30.30.51.2-0.70.70.50.40.30.81.10.71.0-0.2
Delay disc. indifference point, 0s delay0.20.21.5-0.10.00.5-0.3-0.60.6-0.10.60.1-0.2-0.1-0.2-0.60.1-0.3-0.3-0.6-0.6-0.3-0.2-0.0-0.0-0.2-0.30.0-0.41.2
Delay disc. indifference point, 16s delay0.80.91.80.7-0.8-0.31.00.70.31.0-0.6-1.10.31.21.30.70.91.11.00.70.41.21.31.11.11.21.11.31.20.8
Delay disc. indifference point, 2s delay0.70.82.8-1.51.4-0.50.10.01.2-1.20.01.30.6-0.0-0.4-0.3-1.2-1.3-1.7-0.10.7-0.5-0.9-1.1-1.1-0.5-0.6-0.8-0.90.5
Delay disc. indifference point, 24s delay0.30.30.8-0.30.2-0.80.80.60.50.0-0.6-0.00.70.80.90.5-0.00.10.20.7-0.30.50.50.20.20.60.70.60.60.6
Delay disc. indifference point, 4s delay0.20.22.1-0.0-0.10.30.10.00.80.40.1-0.4-0.10.50.4-0.30.30.1-0.2-0.30.30.10.20.20.20.20.00.40.01.5
Delay disc. indifference point, 8s delay0.10.10.30.0-0.00.5-0.5-0.40.10.10.4-0.1-0.4-0.3-0.4-0.5-0.0-0.2-0.3-0.50.0-0.4-0.3-0.1-0.1-0.3-0.5-0.3-0.40.2
Indifference point function ln k0.50.92.5-0.91.0-0.3-0.20.10.6-1.0-0.11.10.2-0.6-1.0-0.3-1.3-1.4-1.3-0.30.8-0.8-1.1-1.6-1.5-0.9-0.9-1.2-1.1-0.9
Indifference point function log k0.50.92.5-0.91.0-0.3-0.20.10.6-1.0-0.11.10.2-0.6-1.0-0.3-1.3-1.4-1.3-0.30.8-0.8-1.1-1.6-1.5-0.9-0.9-1.2-1.1-0.9
Patch foraging total patch changes 0 sec1.12.06.2-1.61.9-0.5-0.5-0.3-0.3-1.40.31.5-0.3-1.0-1.5-0.4-1.5-1.6-2.5-0.80.4-1.5-1.9-1.7-1.6-1.7-1.4-2.1-1.7-2.1
Patch foraging total patch changes 12 sec1.21.65.3-1.61.8-0.4-0.5-0.70.3-1.50.61.5-0.0-0.6-1.2-0.4-1.5-1.4-2.3-0.6-0.6-1.3-1.7-1.5-1.4-1.4-1.2-1.7-1.5-1.4
Patch foraging total patch changes 18 sec0.10.20.7-0.80.8-0.70.30.20.1-0.6-0.20.60.40.20.10.2-0.5-0.4-0.80.10.5-0.1-0.3-0.2-0.2-0.20.0-0.3-0.2-0.0
Patch foraging total patch changes 24 sec0.91.65.3-1.41.7-0.5-0.4-0.2-0.2-1.40.21.4-0.1-0.9-1.2-0.4-1.5-1.4-2.3-0.70.5-1.3-1.6-1.5-1.4-1.5-1.2-1.8-1.5-1.6
Patch foraging total patch changes 6 sec0.40.52.1-1.31.4-0.7-0.2-0.1-0.4-1.10.11.00.2-0.1-0.60.4-0.8-0.7-1.10.0-0.1-0.7-1.0-0.8-0.7-0.7-0.2-0.7-0.5-1.1
Patch foraging time to switch 0 sec0.10.21.00.1-0.10.8-0.7-0.6-0.30.20.7-0.2-0.7-0.4-0.3-0.60.60.3-0.0-0.40.8-0.2-0.10.50.6-0.2-0.30.2-0.11.0
Patch foraging water rate 0 sec0.00.11.40.10.0-0.50.40.4-0.30.1-0.50.00.10.10.20.3-0.1-0.0-0.10.10.00.10.1-0.2-0.2-0.10.0-0.3-0.1-1.2
Patch foraging water rate 12 sec0.10.11.60.3-0.3-0.40.10.3-0.5-0.0-0.10.10.20.10.2-0.10.10.10.70.0-1.3-0.20.10.10.1-0.20.20.20.10.0
Patch foraging water rate 18 sec1.42.25.3-0.10.30.5-1.6-1.0-1.8-0.61.10.8-1.3-2.3-1.8-1.6-0.7-1.1-1.3-1.7-0.8-2.0-1.7-1.3-1.3-2.2-2.0-2.1-1.9-1.9
Patch foraging water rate 24 sec0.91.22.70.3-0.21.3-1.5-1.6-0.70.11.6-0.0-1.4-1.4-1.4-1.70.2-0.6-0.6-1.6-1.1-1.5-1.0-0.4-0.5-1.5-1.5-1.0-1.40.1
Patch foraging water rate 6 sec0.40.61.7-0.90.9-0.90.20.50.3-1.2-0.41.30.7-0.3-0.40.1-1.2-1.2-0.70.20.0-0.4-0.7-1.2-1.3-0.5-0.4-0.9-0.6-1.1
Seeking ratio, delayed vs. immediate footshock2.53.16.30.6-0.8-1.01.91.70.51.3-1.6-1.40.92.22.51.71.51.61.51.71.42.32.31.81.82.32.32.42.31.7
Distance traveled before self-admin0.20.31.8-0.80.80.00.10.01.4-0.50.10.50.30.4-0.2-0.4-0.5-0.8-0.8-0.2-0.4-0.3-0.4-0.6-0.6-0.1-0.3-0.2-0.50.7
Distance traveled after self-admin0.10.10.70.1-0.10.6-0.1-0.30.60.40.3-0.5-0.30.30.0-0.30.40.20.0-0.3-0.7-0.00.10.30.30.1-0.00.3-0.10.8
Extensor digitorum longus weight3.614.228.64.4-4.71.31.51.4-0.94.9-1.3-4.9-0.82.53.91.25.15.15.21.50.33.64.95.35.33.83.55.24.24.0
Bone: elastic displacement0.40.51.5-0.70.8-0.9-0.30.1-0.5-1.1-0.21.10.6-0.3-0.40.3-1.1-0.7-0.00.2-0.7-0.6-0.8-0.9-0.9-0.6-0.2-0.7-0.2-1.2
Bone: elastic work1.01.33.7-1.81.9-1.70.30.6-0.0-1.9-0.71.71.20.2-0.41.0-1.7-1.3-1.00.60.4-0.5-1.1-1.4-1.4-0.60.0-1.0-0.3-1.7
Bone: endosteal estimation2.65.617.8-2.21.9-2.83.63.14.2-1.0-3.01.03.23.52.52.4-1.3-0.9-1.42.83.42.51.4-0.5-0.52.42.11.21.32.1
Bone: endosteal perimeter4.39.121.9-2.52.2-3.84.64.44.7-1.0-4.31.14.14.23.33.6-1.7-0.7-1.34.03.93.31.9-0.6-0.63.22.91.52.01.4
Epididymis fat weight0.20.52.10.5-0.6-0.50.90.9-0.20.5-0.9-0.50.40.40.90.60.40.60.60.61.51.01.10.80.80.90.70.60.8-0.2
Delta time in closed arm before/after self-admin2.01.95.62.3-2.01.6-0.9-0.9-2.42.20.7-2.2-2.1-0.9-0.2-0.31.81.91.1-1.00.0-0.00.61.51.5-0.1-0.30.10.3-1.5
Delta time in open arm before/after self-admin0.40.44.7-0.40.20.20.50.12.2-0.2-0.20.20.80.80.20.4-0.4-0.5-0.10.5-0.30.60.2-0.3-0.30.70.50.50.21.0
Diff in mean of infusions in LGA sessions0.20.31.1-0.80.7-0.40.10.31.1-0.7-0.20.70.70.4-0.10.2-0.7-0.7-0.40.2-0.6-0.1-0.3-0.7-0.70.10.0-0.3-0.20.1
Delay discount exponential model param0.20.20.80.00.00.2-0.5-0.4-0.7-0.40.40.4-0.3-0.8-0.7-0.3-0.3-0.30.0-0.3-0.5-0.5-0.5-0.4-0.4-0.6-0.5-0.6-0.4-0.9
Extinction: sum of active levers before priming0.10.10.3-0.20.30.00.40.50.30.3-0.5-0.3-0.10.60.30.50.30.3-0.20.00.30.30.20.30.30.20.40.40.40.0
Active lever presses in extinction session 62.72.76.2-1.71.5-2.32.42.22.3-0.8-2.20.82.52.41.52.3-1.0-0.5-0.32.41.11.70.9-0.4-0.41.71.81.01.40.4
Bone: final force1.42.26.2-1.41.7-0.5-0.6-0.7-0.4-1.70.61.7-0.1-1.1-1.6-0.4-1.8-1.7-2.1-0.90.7-1.5-1.9-1.8-1.8-1.7-1.5-2.2-1.8-2.5
Bone: final moment1.72.86.5-1.61.9-0.5-0.8-0.8-0.5-1.90.81.9-0.2-1.3-1.8-0.6-2.0-1.9-2.4-1.00.7-1.8-2.2-2.0-2.0-2.0-1.7-2.5-2.1-2.6
Food consumed during 24 hour testing period0.71.02.50.5-0.5-1.01.21.3-0.10.4-1.3-0.41.01.01.11.60.20.71.31.3-0.71.21.20.60.61.21.50.91.3-0.8
Glucose0.71.23.51.9-1.91.3-0.4-0.6-1.01.70.6-1.7-1.3-0.40.4-0.81.61.51.1-0.8-1.00.20.91.41.40.2-0.10.70.20.3
Heart weight2.94.610.30.8-0.8-2.32.53.2-0.61.1-3.1-1.11.62.22.92.70.91.91.82.62.02.72.61.81.72.42.72.12.8-1.0
Delay discount hyperbolic model param0.20.20.80.2-0.10.2-0.5-0.4-0.8-0.30.40.3-0.3-0.8-0.6-0.3-0.1-0.10.2-0.2-0.6-0.5-0.4-0.2-0.2-0.5-0.4-0.4-0.3-0.9
Intermittent access intake day 1-15 change0.61.23.81.7-1.71.0-0.1-0.1-1.01.90.2-1.9-1.2-0.10.6-0.21.71.70.9-0.30.70.51.11.61.60.40.20.70.50.2
Intermittent access intake escalation0.51.03.41.6-1.51.1-0.1-0.2-0.91.80.2-1.8-1.3-0.20.5-0.41.61.60.5-0.50.90.41.01.51.50.2-0.00.50.20.3
Intermittent access intake escalation 20.70.82.81.3-1.20.70.30.6-0.71.6-0.3-1.5-0.9-0.00.50.11.31.40.4-0.11.70.71.01.21.20.50.20.50.4-0.0
Intermitt. access day 1 inactive lever presses0.83.07.7-1.61.5-2.12.42.52.4-0.8-2.60.92.51.91.02.8-1.6-0.7-0.72.51.81.80.7-0.9-0.91.61.60.31.1-1.3
Intermitt. access day 15 inactive lever presses1.32.610.3-2.32.2-1.31.00.53.2-2.2-0.62.32.10.6-0.50.6-2.6-2.5-2.00.90.2-0.0-1.1-2.3-2.3-0.0-0.2-1.0-0.9-0.0
Intermitt. access escalation Index0.40.61.20.9-1.00.30.70.70.80.9-0.6-0.80.30.60.90.30.60.80.90.50.21.11.10.80.81.00.81.00.81.1
Intermittent access day 1 total infusions0.61.02.1-0.20.1-0.71.31.01.40.1-1.0-0.21.01.41.21.20.20.20.41.01.31.41.00.50.51.41.31.31.21.4
Intermittent access day 15 total infusions1.21.73.00.8-0.90.11.30.90.91.5-0.8-1.60.11.61.61.11.41.50.70.71.51.71.71.61.61.61.41.71.41.5
Intermittent access terminal intake (last 3 days)1.31.73.90.2-0.3-0.41.61.41.80.8-1.1-0.80.91.81.61.30.60.70.31.12.01.91.51.01.01.81.51.61.31.8
Intermittent access total infusions2.32.75.50.4-0.5-0.91.91.61.31.1-1.5-1.21.12.32.21.91.01.31.11.51.52.32.01.51.52.32.22.12.01.5
Intermittent access day 1 locomotion1.11.44.5-0.60.6-1.51.61.41.0-0.1-1.4-0.01.41.91.32.1-0.00.30.51.70.71.50.90.30.31.51.81.21.40.0
Intermittent access day 15 total locomotion0.50.91.60.6-0.6-0.30.80.5-0.11.0-0.6-1.10.11.11.21.11.11.20.90.50.21.11.21.21.21.11.21.31.20.3
Intermittent access total locomotion1.31.53.9-0.40.4-1.51.71.50.90.1-1.5-0.21.31.91.62.00.30.60.51.60.91.61.20.60.61.61.81.41.50.4
Intermittent access standard deviation0.10.23.00.3-0.30.40.2-0.10.10.60.0-0.6-0.30.10.00.50.20.4-0.20.11.70.60.30.20.20.40.1-0.00.2-0.4
Left kidney weight0.10.44.00.6-0.5-0.90.20.6-2.00.0-0.5-0.10.0-0.50.50.30.20.70.70.20.50.10.30.50.5-0.00.2-0.00.4-1.3
Right kidney weight0.41.64.10.4-0.4-2.01.41.9-1.60.2-1.8-0.31.01.01.81.70.51.21.41.40.51.21.31.11.11.11.61.01.7-1.0
Cocaine induced anxiety0.30.43.40.5-0.40.2-0.7-0.6-1.80.20.6-0.1-0.7-1.0-0.5-0.30.10.30.3-0.10.1-0.6-0.30.00.0-0.7-0.6-0.7-0.2-1.8
Post-drug Anxiety0.30.43.7-0.40.5-1.20.20.5-1.4-0.3-0.40.40.4-0.10.10.7-0.40.10.20.9-0.1-0.1-0.1-0.2-0.2-0.20.2-0.40.3-1.9
Baseline Anxiety1.41.64.2-1.51.3-1.91.71.71.9-1.0-1.60.92.11.71.11.6-0.9-0.6-0.31.6-0.01.10.4-0.4-0.41.21.40.80.90.9
Tail length0.72.78.7-2.62.6-3.01.41.70.5-2.3-1.82.32.30.80.11.9-2.1-1.6-1.11.80.50.2-0.7-1.7-1.70.20.7-0.70.3-1.8
Length with tail0.83.613.8-1.41.4-3.72.73.2-0.4-0.9-3.10.82.51.82.03.1-0.70.20.22.71.41.71.10.20.21.52.30.92.0-1.6
Length without tail0.72.44.40.9-0.9-1.81.72.0-1.50.9-1.8-1.00.91.12.11.81.11.71.91.50.61.61.81.71.81.52.01.72.0-0.5
Times rat made contact with spout0.30.32.20.3-0.3-0.70.40.5-1.00.1-0.5-0.10.50.10.21.0-0.20.40.90.6-0.80.30.30.10.00.30.60.10.7-1.5
Lifetime Intake2.12.55.5-0.1-0.0-1.32.11.81.60.6-1.7-0.61.52.32.12.00.50.80.71.71.82.21.71.01.02.22.11.91.91.3
Liver weight, left0.71.14.7-1.01.0-2.21.51.50.0-1.0-1.61.01.50.60.91.4-1.0-0.5-0.41.41.40.70.3-0.5-0.50.50.8-0.20.4-1.3
Liver weight, right0.40.75.9-0.00.2-0.4-0.5-0.6-1.6-0.70.40.7-0.1-1.4-0.9-0.0-0.8-0.60.1-0.5-0.2-0.8-0.9-0.8-0.8-1.0-0.6-1.0-0.6-2.4
Locomotor activity0.91.43.4-1.81.8-1.50.90.81.6-1.6-0.81.71.40.8-0.10.8-1.6-1.5-1.70.70.20.0-0.6-1.5-1.5-0.00.1-0.8-0.4-0.9
Locomotor testing distance1.01.85.6-2.32.2-1.31.00.92.4-1.7-0.91.71.41.10.10.6-1.5-1.6-2.20.71.50.2-0.6-1.5-1.50.10.0-0.6-0.50.1
Locomotor testing rearing0.40.83.7-1.81.7-0.60.50.11.9-1.1-0.21.10.80.9-0.10.2-0.9-1.1-1.80.40.60.0-0.6-0.9-0.90.10.0-0.2-0.31.0
Locomotion in novel chamber0.60.82.3-1.11.0-1.0-0.0-0.00.9-1.50.21.50.90.20.1-0.8-0.9-1.3-0.9-0.3-1.5-0.7-0.7-1.0-1.0-0.5-0.4-0.4-0.71.4
Locomotion in novel chamber post-restriction0.10.21.0-0.50.6-0.50.40.5-0.0-0.2-0.60.30.20.0-0.00.5-0.4-0.2-0.60.21.00.2-0.1-0.2-0.2-0.00.1-0.3-0.0-0.9
Fecal boli incidents, locomotor time 10.10.20.70.2-0.20.4-0.4-0.3-0.50.10.4-0.1-0.5-0.6-0.6-0.5-0.1-0.1-0.2-0.4-0.1-0.5-0.4-0.2-0.2-0.6-0.6-0.7-0.5-0.8
Change in fecal boli incidents, locomotor task0.10.10.4-0.40.4-0.60.40.6-0.2-0.1-0.60.10.30.30.40.5-0.10.1-0.10.20.60.30.10.00.00.30.40.20.4-0.1
Time >=10cm from walls, locomotor time 10.20.21.50.4-0.40.3-0.4-0.4-0.1-0.10.50.0-0.1-0.2-0.1-0.70.2-0.10.7-0.3-1.2-0.3-0.00.10.1-0.1-0.10.3-0.01.0
Bouts of movement, locomotor time 10.40.41.41.2-1.21.1-0.5-0.6-0.60.90.6-0.9-0.7-0.6-0.2-0.40.70.61.0-0.3-0.3-0.00.30.50.5-0.0-0.20.30.10.0
Total resting periods, locomotor time 10.40.41.51.2-1.20.8-0.3-0.4-0.80.90.3-0.9-0.6-0.5-0.0-0.10.70.71.2-0.1-0.40.10.50.60.60.20.10.40.4-0.3
Rest time, locomotor task time 10.10.10.50.2-0.20.7-0.5-0.40.0-0.10.50.0-0.3-0.7-0.6-0.4-0.2-0.30.1-0.4-0.1-0.4-0.4-0.3-0.3-0.3-0.4-0.2-0.30.1
Distance moved, locomotor task time 10.71.02.5-0.10.0-1.21.31.50.40.3-1.4-0.31.01.61.61.00.50.70.51.00.21.21.20.80.81.21.31.11.20.8
Vertical activity count, locomotor time 10.30.71.90.1-0.1-0.71.01.00.70.5-0.9-0.50.71.41.30.60.50.60.40.80.31.01.00.70.71.01.01.00.91.2
Time >=10cm from walls, locomotor time 20.20.20.7-0.60.6-0.80.20.20.4-0.8-0.20.80.70.2-0.00.1-0.7-0.7-0.30.3-0.5-0.2-0.3-0.6-0.6-0.1-0.1-0.3-0.2-0.2
Bouts of movement, locomotor time 20.10.20.5-0.70.7-0.3-0.2-0.20.1-0.70.10.70.2-0.2-0.40.0-0.6-0.6-0.60.00.7-0.3-0.5-0.6-0.6-0.3-0.3-0.5-0.3-0.6
Total resting periods, locomotor time 20.10.10.6-0.30.30.0-0.3-0.3-0.2-0.30.30.3-0.1-0.4-0.4-0.1-0.3-0.3-0.3-0.20.8-0.2-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.5
Rest time, locomotor task time 20.60.72.01.2-1.20.40.30.3-0.41.1-0.3-1.1-0.10.30.70.60.91.11.40.40.81.01.01.01.00.90.81.01.0-0.0
Distance moved, locomotor task time 20.10.10.6-0.30.3-0.40.20.30.4-0.2-0.20.20.20.40.3-0.10.0-0.2-0.4-0.1-0.50.00.10.10.10.10.10.2-0.00.8
Vertical activity count, locomotor time 20.20.31.2-0.91.0-0.20.0-0.11.1-0.70.10.70.30.2-0.4-0.2-0.7-0.9-1.1-0.1-0.4-0.4-0.6-0.7-0.7-0.3-0.3-0.4-0.60.4
Light reinforcement 10.51.23.2-1.51.6-0.6-0.10.10.7-1.5-0.11.50.5-0.3-0.90.1-1.6-1.4-1.8-0.20.1-0.8-1.2-1.4-1.5-0.9-0.7-1.4-1.0-1.3
Light reinforcement 20.71.13.0-1.31.3-0.4-0.3-0.20.6-1.40.21.50.3-0.6-0.9-0.2-1.5-1.4-1.7-0.30.4-0.8-1.3-1.5-1.4-1.0-1.0-1.5-1.2-1.1
Bone: marrow area2.55.517.3-2.11.9-2.83.53.14.2-0.9-3.01.03.13.42.52.4-1.3-0.8-1.42.83.42.51.4-0.5-0.52.42.11.21.22.0
Bone: maximum diameter1.12.16.4-1.91.9-1.71.61.62.5-1.4-1.61.51.71.20.41.2-2.0-1.5-2.01.42.20.7-0.3-1.5-1.50.50.2-0.7-0.4-0.5
Bone: maximum force0.61.04.5-1.51.7-1.30.70.80.3-1.1-0.71.10.60.4-0.10.8-1.2-0.9-1.80.42.1-0.1-0.6-0.9-0.9-0.3-0.1-0.9-0.5-1.4
Bone: maximum moment0.71.24.3-1.61.8-1.30.50.50.2-1.4-0.51.40.50.0-0.40.5-1.4-1.2-2.10.12.0-0.4-0.9-1.1-1.1-0.7-0.4-1.2-0.9-1.4
Mean time between licks in bursts1.63.97.31.9-1.9-0.51.61.8-1.32.4-1.7-2.30.21.32.31.72.12.72.41.71.02.32.72.52.62.22.22.32.5-0.1
Mean num. licks in bursts0.40.71.4-0.10.30.6-0.8-1.0-0.3-0.20.90.2-0.8-1.0-1.1-0.9-0.4-0.7-1.0-1.1-0.3-1.0-0.9-0.7-0.7-1.0-1.2-1.2-1.2-0.5
Cd content in liver2.32.67.52.7-2.72.7-1.4-1.4-1.12.11.5-2.1-2.3-1.2-0.2-1.82.21.61.3-1.7-0.6-0.20.61.71.7-0.2-0.60.7-0.11.6
Co content in liver0.50.64.00.2-0.5-0.30.30.40.8-0.4-0.20.40.80.70.7-0.10.2-0.01.20.8-1.90.40.40.20.20.70.71.10.72.0
Cu content in liver0.70.82.5-1.21.0-1.10.60.71.2-1.3-0.71.21.60.60.11.0-1.3-1.00.41.30.30.4-0.3-1.1-1.10.50.60.10.40.1
Fe content in liver0.40.52.10.7-0.61.0-1.5-0.7-1.10.30.9-0.4-1.0-0.9-0.5-1.00.50.20.7-0.9-0.6-0.9-0.50.20.2-0.7-0.7-0.2-0.30.3
K content in liver2.12.04.7-1.61.5-0.1-0.9-1.11.1-2.11.02.10.6-0.8-1.6-0.9-1.9-2.2-1.0-0.6-1.2-1.4-1.9-2.1-2.1-1.2-1.2-1.4-1.40.1
Mg content in liver4.44.59.3-0.50.41.8-2.7-2.90.3-1.72.81.7-0.9-2.3-3.1-2.4-1.6-2.3-0.5-2.2-2.8-2.6-2.7-2.3-2.3-2.3-2.5-2.1-2.5-0.1
Mn content in liver6.36.913.1-1.61.80.7-2.3-2.3-0.3-2.52.22.5-0.6-2.7-3.5-1.9-2.8-3.1-2.3-2.2-2.6-3.2-3.5-3.3-3.3-3.2-3.0-3.6-3.3-2.7
Na content in liver0.50.52.6-1.10.90.1-0.2-0.31.6-0.90.20.80.50.4-0.2-0.1-0.7-0.9-0.9-0.00.9-0.1-0.6-0.7-0.70.0-0.10.1-0.21.6
Rb content in liver2.83.25.9-0.80.71.2-2.2-2.20.0-1.72.21.7-0.8-2.1-2.4-2.3-1.2-2.0-0.9-1.8-1.8-2.3-2.4-1.8-1.8-2.1-2.2-1.8-2.20.0
Se content in liver0.50.63.31.4-1.41.2-0.6-0.4-0.71.00.4-1.1-0.6-0.3-0.1-0.10.90.91.8-0.3-1.10.20.50.70.70.30.20.60.6-0.2
Sr content in liver0.90.81.80.7-0.9-0.40.90.80.70.6-0.7-0.60.70.91.20.30.60.61.31.0-0.80.91.10.70.71.10.91.10.91.3
Zn content in liver0.20.20.6-0.0-0.00.4-0.7-0.6-0.3-0.50.60.5-0.2-0.7-0.6-0.5-0.2-0.40.2-0.40.6-0.5-0.6-0.4-0.4-0.4-0.5-0.2-0.30.7
Bone: minimum diameter3.36.013.8-2.92.8-3.73.63.43.4-1.9-3.42.03.52.91.82.9-2.4-1.5-2.03.02.92.00.6-1.4-1.41.81.80.10.8-0.3
Time in familiar zone, hab. session 10.90.82.61.4-1.41.1-0.2-0.3-0.71.60.3-1.6-1.00.10.2-0.01.51.30.9-0.5-0.70.50.91.21.20.50.30.70.50.1
Time in novel zone, hab. session 10.30.31.0-0.80.7-0.80.30.40.4-0.9-0.31.00.90.00.10.1-1.0-0.8-0.10.60.5-0.2-0.4-0.7-0.7-0.1-0.0-0.2-0.10.4
Total zone transitions, hab. session 10.91.23.51.9-1.90.7-0.0-0.1-1.21.60.2-1.6-0.80.00.7-0.11.71.61.7-0.1-1.20.51.21.51.50.40.50.90.7-0.0
Total locomotion distance, hab. session 10.00.10.4-0.20.3-0.60.30.3-0.0-0.3-0.20.30.20.10.20.1-0.1-0.2-0.50.0-0.3-0.1-0.0-0.2-0.2-0.20.0-0.3-0.2-0.6
Locomotion velocity, hab. session 10.10.10.6-0.30.3-0.70.50.50.1-0.3-0.40.30.30.30.30.3-0.1-0.2-0.60.1-0.10.10.1-0.1-0.1-0.00.1-0.2-0.1-0.6
Time in familiar zone, hab. session 20.90.92.51.1-0.90.10.10.3-1.51.2-0.3-1.4-0.50.30.60.81.41.61.20.2-0.00.71.01.41.40.71.01.01.2-0.5
Time in novel zone, hab. session 21.11.12.7-0.90.8-0.2-0.4-0.41.0-1.40.51.50.3-0.7-0.8-1.1-1.4-1.6-1.3-0.5-0.2-1.0-1.2-1.5-1.5-1.0-1.2-1.2-1.40.3
Total zone transitions, hab. session 20.81.13.41.7-1.81.0-0.6-0.8-1.01.20.9-1.2-0.9-0.20.2-0.71.51.11.7-0.6-1.8-0.10.71.21.20.10.20.80.40.8
Total locomotion distance, hab. session 20.40.51.41.2-1.20.8-0.6-0.6-0.80.80.7-0.8-0.7-0.3-0.0-0.51.10.71.1-0.5-1.1-0.10.40.80.80.00.00.50.20.3
Locomotion velocity, hab. session 20.50.61.91.4-1.40.9-0.6-0.7-0.91.00.7-1.0-0.9-0.30.0-0.61.20.91.1-0.6-1.0-0.10.51.01.0-0.00.00.50.20.3
Novel to familiar place preference ratio0.30.32.6-0.80.8-0.60.60.50.5-0.6-0.50.60.40.30.10.4-0.6-0.4-1.00.31.60.2-0.2-0.4-0.40.00.0-0.2-0.1-0.2
Novelty place preference0.30.32.1-0.80.8-0.50.40.40.4-0.6-0.30.70.30.0-0.10.2-0.7-0.6-1.10.21.4-0.0-0.4-0.5-0.5-0.2-0.2-0.4-0.3-0.2
Time in novel zone, NPP test0.30.31.4-0.70.7-0.50.30.30.3-0.7-0.20.70.3-0.1-0.20.1-0.8-0.6-1.00.11.2-0.2-0.5-0.6-0.6-0.3-0.3-0.5-0.4-0.4
Total zone transitions, NPP test1.11.63.61.9-1.81.9-1.4-1.8-1.21.21.8-1.1-1.8-1.5-0.7-1.81.20.60.7-1.7-1.5-1.0-0.10.60.6-0.9-1.2-0.4-0.90.1
Total locomotion distance, NPP test0.20.30.80.5-0.40.5-0.6-0.7-0.50.00.70.0-0.6-0.8-0.5-0.80.0-0.2-0.2-0.9-0.5-0.7-0.4-0.2-0.2-0.8-0.8-0.7-0.8-0.6
Locomotion velocity, NPP test0.10.20.50.7-0.60.6-0.4-0.6-0.30.40.6-0.3-0.6-0.5-0.2-0.60.40.2-0.0-0.7-0.2-0.3-0.00.20.2-0.4-0.5-0.2-0.5-0.2
Intraocular pressure0.60.91.90.3-0.5-0.51.11.30.60.5-1.2-0.50.81.21.11.10.40.70.81.20.41.31.20.70.71.41.31.21.40.7
Delta distance traveled before/after self-admin0.20.20.50.7-0.70.6-0.3-0.5-0.60.60.3-0.6-0.5-0.3-0.10.10.50.60.6-0.3-0.10.10.20.50.50.00.00.10.1-0.3
Delta ambulatory time before/after self-admin0.30.41.20.8-0.70.10.30.2-0.90.9-0.3-0.9-0.40.10.40.70.71.10.70.20.40.60.70.80.80.40.50.40.6-0.8
Parametrial fat weight0.40.82.7-0.70.9-0.4-0.5-0.1-0.8-0.80.30.9-0.2-0.9-0.9-0.4-1.0-0.9-1.3-0.40.3-1.0-1.1-1.1-1.0-1.1-1.1-1.5-1.1-1.7
Pavlov. Cond. lever latency1.41.85.22.3-2.22.2-1.2-1.4-0.51.91.3-1.8-1.7-0.8-0.2-1.51.51.11.3-1.6-2.1-0.40.41.11.1-0.3-0.60.3-0.30.7
Pavlov. Cond. magazine entry latency2.83.510.5-3.13.2-1.6-0.1-0.10.2-3.1-0.02.91.0-0.6-1.60.4-2.4-2.4-2.80.31.8-1.2-2.2-2.4-2.4-1.4-0.9-1.9-1.3-1.6
Pavlov. Cond. change in total contacts1.71.85.8-2.42.3-1.40.50.51.1-2.3-0.52.21.50.4-0.81.0-1.9-1.8-1.31.01.3-0.2-1.1-1.8-1.8-0.20.0-0.8-0.3-0.6
Pavlov. Cond. index score1.92.37.7-2.72.8-1.80.60.60.6-2.5-0.72.41.30.2-0.71.0-2.0-1.8-2.20.92.3-0.4-1.3-1.7-1.7-0.5-0.2-1.1-0.5-1.0
Pavlov. Cond. latency score1.72.17.2-2.72.7-1.90.70.80.4-2.4-0.82.31.40.3-0.61.1-1.9-1.6-1.91.12.0-0.3-1.2-1.6-1.6-0.40.0-0.9-0.3-1.1
Pavlov. Cond. lever contacts1.61.95.5-2.32.3-2.21.21.40.8-2.0-1.41.91.80.90.21.5-1.6-1.1-1.31.62.30.4-0.4-1.1-1.10.30.7-0.20.3-0.4
Pavlov. Cond. magazine entry number3.34.210.33.1-3.21.10.70.7-0.43.1-0.5-3.0-0.70.92.10.12.62.73.00.3-1.41.72.62.72.71.81.42.31.81.5
Pavlov. Cond. intertrial magazine entries0.91.12.20.5-0.6-0.01.21.11.11.1-1.1-1.00.51.31.11.10.70.90.70.90.51.51.40.90.91.41.31.21.20.9
Pavlov. Cond. lever-magazine prob. diff.2.22.78.7-2.93.0-1.80.60.60.8-2.7-0.62.61.40.1-0.90.9-2.2-2.0-2.30.92.2-0.5-1.5-2.0-2.0-0.6-0.3-1.2-0.7-1.0
Pavlov. Cond. response bias3.54.312.8-3.53.6-1.90.10.10.7-3.4-0.23.31.3-0.4-1.50.4-2.8-2.8-3.10.41.9-1.3-2.3-2.7-2.7-1.4-0.9-2.0-1.4-1.4
Pavlov. Cond. lever latency0.40.61.61.1-1.10.40.10.2-0.81.1-0.2-1.1-0.50.10.60.21.11.31.10.20.30.60.91.11.10.50.50.70.70.1
Pavlov. Cond. magazine entry latency0.30.40.90.9-0.90.8-0.4-0.5-0.30.70.6-0.7-0.7-0.10.1-0.50.90.70.7-0.4-0.70.00.30.80.80.1-0.00.50.10.9
Pavlov. Cond. change in total contacts0.60.93.6-1.61.4-0.80.30.21.9-1.6-0.21.61.20.5-0.20.0-1.3-1.5-0.80.6-0.5-0.2-0.7-1.1-1.1-0.00.0-0.1-0.31.4
Pavlov. Cond. index score0.20.21.2-0.60.5-0.30.1-0.11.1-0.70.10.70.50.2-0.1-0.2-0.7-0.8-0.40.1-0.8-0.2-0.4-0.5-0.5-0.1-0.1-0.1-0.30.7
Pavlov. Cond. latency score0.20.21.4-0.70.6-0.40.30.11.2-0.7-0.10.70.60.40.1-0.0-0.7-0.7-0.40.3-0.5-0.0-0.3-0.5-0.50.00.0-0.0-0.20.8
Pavlov. Cond. lever contacts0.50.71.7-1.11.0-0.3-0.3-0.40.6-1.20.41.20.3-0.4-0.8-0.4-1.1-1.3-1.1-0.4-0.4-0.7-1.1-1.2-1.2-0.7-0.7-0.9-0.9-0.3
Pavlov. Cond. magazine entry number0.40.52.0-0.60.6-0.91.01.00.4-0.2-1.10.30.90.60.51.1-0.5-0.1-0.21.01.40.70.4-0.3-0.30.70.60.00.6-0.8
Pavlov. Cond. intertrial magazine entries1.62.45.3-1.81.7-2.12.11.91.9-1.3-2.11.42.31.30.82.0-1.9-1.0-1.02.22.31.30.3-1.1-1.21.11.0-0.30.5-1.2
Pavlov. Cond. lever-magazine prob. diff.0.10.21.0-0.50.4-0.20.1-0.11.0-0.60.10.60.40.2-0.0-0.2-0.5-0.6-0.20.1-0.8-0.1-0.3-0.3-0.4-0.0-0.00.0-0.30.8
Pavlov. Cond. response bias0.50.71.2-0.60.60.2-0.8-0.80.3-0.90.80.9-0.2-0.7-1.0-0.8-0.8-1.0-1.0-0.8-0.9-1.0-1.1-0.9-0.9-1.0-0.9-0.9-1.1-0.1
Time in closed arm before self-admin1.21.53.20.10.01.0-1.8-1.3-1.5-0.31.40.4-1.2-1.6-1.7-1.3-0.3-0.5-0.2-1.3-1.8-1.7-1.3-0.6-0.6-1.7-1.5-1.4-1.3-1.7
Time in closed arm after self-admin4.04.211.82.7-2.42.9-2.7-2.3-3.42.02.4-2.0-3.4-2.4-1.6-2.01.91.51.1-2.4-1.9-1.6-0.41.21.2-1.6-1.7-0.8-1.0-1.7
Time in open arm before self-admin2.72.96.71.3-1.4-0.81.71.9-0.31.5-1.7-1.60.41.52.60.91.81.91.51.01.81.92.32.02.01.91.82.32.02.1
Time in open arm after self-admin4.04.39.2-0.80.5-2.33.02.82.5-0.1-2.80.12.73.02.72.5-0.10.40.62.71.62.72.00.60.62.72.72.22.31.6
Bone: periosteal estimation1.94.110.2-2.82.7-2.72.62.33.2-1.9-2.32.02.72.11.01.9-2.3-1.8-2.32.13.01.1-0.1-1.6-1.61.00.9-0.4-0.00.0
Bone: periosteal perimeter2.54.28.9-2.32.1-2.93.03.02.7-1.2-2.91.22.82.71.92.5-1.5-0.8-1.22.82.91.90.8-0.8-0.81.71.80.71.10.4
Bone: post-yield work2.53.78.2-0.40.3-2.12.72.91.10.5-2.7-0.51.82.52.52.40.51.00.42.62.52.52.11.21.22.42.42.02.21.0
Progressive ratio test 1 active lever presses1.01.34.9-0.70.6-1.11.61.22.2-0.3-1.10.31.61.71.31.3-0.4-0.3-0.21.41.21.40.80.00.01.41.31.00.91.3
Progressive ratio test 1 breakpoint1.21.55.2-0.80.7-1.31.81.32.3-0.3-1.30.31.71.81.31.6-0.5-0.3-0.21.61.31.50.90.00.01.51.51.01.01.1
Progressive ratio test 1 inactive lever presses1.62.35.3-1.91.8-2.01.91.92.2-1.2-2.01.22.21.80.72.3-1.5-1.0-1.02.01.71.30.2-1.0-1.01.21.30.20.8-0.6
Progressive ratio test 2 active lever presses1.01.24.2-0.90.8-1.21.51.32.1-0.4-1.20.31.61.71.21.3-0.4-0.3-0.21.40.81.30.7-0.1-0.11.31.30.90.91.1
Progressive ratio test 2 breakpoint1.11.24.4-0.90.8-1.21.51.32.1-0.4-1.20.31.51.81.21.3-0.4-0.3-0.21.40.81.30.7-0.1-0.11.31.30.90.91.2
Progressive ratio test 2 inactive lever presses1.32.15.4-1.00.9-1.62.01.92.0-0.3-1.90.32.02.11.32.3-0.7-0.1-0.11.91.51.81.0-0.1-0.11.71.70.91.3-0.1
Incentive Sensitization - Responses0.50.72.7-1.11.0-0.90.90.91.7-0.8-0.70.81.21.00.60.5-0.6-0.7-0.60.80.70.50.1-0.5-0.50.70.60.40.21.5
Incentive Sensitization - Breakpoint0.50.62.7-1.10.9-0.80.80.81.7-0.8-0.60.71.11.00.60.4-0.5-0.7-0.60.70.60.50.1-0.4-0.40.60.50.40.21.5
Sum of active levers in priming session hrs 5-60.50.57.3-0.30.10.5-0.0-0.31.7-0.10.40.00.30.70.4-0.60.2-0.2-0.10.0-0.40.10.20.20.20.40.20.80.12.7
Progressive ratio0.20.40.8-0.30.30.9-0.7-0.80.3-0.20.90.2-0.6-0.5-0.8-0.7-0.1-0.3-0.8-0.8-0.5-0.7-0.6-0.3-0.3-0.7-0.8-0.7-0.90.3
Food seeking constrained by brief footshock0.10.10.60.1-0.1-0.10.30.10.5-0.1-0.20.00.30.40.30.5-0.00.20.30.2-0.70.40.30.20.20.40.40.20.3-0.3
Seeking ratio, punishment vs. effort0.50.71.8-0.10.1-1.11.11.00.6-0.2-1.20.11.21.11.11.3-0.20.20.71.20.31.10.70.20.21.11.20.81.1-0.4
Retroperitoneal fat weight0.00.21.5-0.20.2-0.5-0.3-0.0-1.2-0.30.10.3-0.2-0.6-0.2-0.4-0.1-0.2-0.2-0.30.2-0.5-0.3-0.2-0.1-0.5-0.4-0.5-0.3-0.4
Reaction time number correct0.20.41.40.2-0.3-0.80.91.20.30.2-1.1-0.10.70.90.90.60.00.10.51.00.00.70.80.10.10.70.70.50.70.1
Reaction time mean minus median0.10.41.0-0.90.8-0.30.30.21.0-0.7-0.20.70.80.4-0.60.8-1.0-0.7-0.10.6-0.70.1-0.4-0.9-0.80.20.2-0.20.1-0.6
Reaction time mean minus median AUC0.41.02.4-1.01.00.4-0.8-0.80.8-1.00.81.00.2-0.5-1.6-0.4-1.3-1.3-0.6-0.4-1.3-1.0-1.3-1.5-1.4-0.9-0.9-1.1-1.0-0.6
Reaction time num false alarms1.01.43.4-0.00.0-1.41.81.91.10.0-1.8-0.01.51.71.41.8-0.20.30.41.60.41.51.10.10.21.41.50.71.2-0.4
Reaction time num false alarms AUC0.71.13.1-0.10.2-1.41.71.71.1-0.2-1.70.21.41.51.01.8-0.50.10.11.50.31.20.8-0.1-0.11.21.20.41.0-0.8
Reaction time trials correct on left0.20.41.40.2-0.3-0.80.91.20.30.2-1.1-0.10.70.90.90.60.00.10.51.00.00.70.80.10.10.70.70.50.70.1
Reaction time trials on left0.20.41.30.1-0.1-0.90.91.10.50.1-1.10.00.80.90.80.6-0.1-0.10.41.0-0.10.60.6-0.0-0.10.60.60.40.60.0
Reaction time mean0.91.54.0-2.01.90.2-0.7-1.01.2-1.70.91.70.5-0.5-1.5-0.2-1.8-1.6-1.0-0.2-0.3-1.0-1.6-1.7-1.6-0.9-0.8-1.1-1.0-0.3
Reaction time mean AUC0.91.43.5-1.91.80.4-0.8-1.11.3-1.51.01.50.3-0.4-1.5-0.4-1.6-1.6-0.9-0.3-0.5-1.1-1.6-1.5-1.5-0.9-0.9-1.0-1.10.1
Median of all reaction times1.11.64.5-2.12.00.1-0.6-1.01.2-1.90.91.80.6-0.5-1.4-0.3-1.8-1.7-1.2-0.3-0.1-1.1-1.7-1.7-1.6-0.9-0.9-1.1-1.1-0.1
Reaction time omissions3.14.611.0-3.23.2-1.0-0.4-0.62.0-3.10.63.11.4-0.5-2.0-0.3-3.2-3.3-2.4-0.0-1.0-1.6-2.6-3.2-3.2-1.5-1.3-2.2-1.9-0.7
Reaction time false alarm rate0.30.41.4-0.10.1-0.71.01.00.9-0.2-1.00.10.80.90.51.2-0.30.1-0.10.80.40.90.5-0.1-0.00.80.80.20.5-0.5
Reaction time premature initiation rate0.30.41.5-1.01.1-1.00.60.90.0-0.4-0.90.40.50.50.11.1-0.4-0.1-0.90.71.00.4-0.1-0.4-0.40.30.4-0.10.3-1.2
Reaction time premature initiations0.40.72.1-0.91.0-1.31.11.40.3-0.3-1.50.30.91.00.51.3-0.5-0.1-0.61.11.00.70.2-0.4-0.40.60.70.00.6-1.2
Std. dev. reaction times0.81.53.5-1.51.40.4-0.9-1.10.8-1.51.11.50.3-0.8-1.9-0.4-1.6-1.6-0.8-0.4-1.1-1.2-1.7-1.7-1.7-1.0-1.0-1.3-1.2-0.9
Reaction time trials completed0.20.41.30.1-0.1-0.90.91.10.50.1-1.10.00.80.90.80.6-0.1-0.10.41.0-0.10.60.6-0.0-0.10.60.60.40.60.0
Reaction time trials AUC0.20.31.10.1-0.2-0.80.81.00.50.1-1.00.00.70.80.70.5-0.1-0.10.50.9-0.10.50.6-0.0-0.10.60.60.30.60.0
Run reversals in cocaine runway, females1.01.02.01.1-1.2-0.10.60.7-0.61.0-0.6-1.00.10.51.00.81.11.31.41.01.41.21.31.11.11.21.01.21.30.4
Run reversals in cocaine runway, males0.30.31.1-0.70.7-1.10.40.1-0.0-0.8-0.50.90.60.10.20.3-0.8-0.5-0.70.31.0-0.0-0.3-0.5-0.5-0.1-0.1-0.6-0.2-1.0
Latency to leave start box in cocaine runway0.70.82.11.4-1.30.30.10.2-1.31.2-0.3-1.3-0.8-0.10.9-0.11.51.40.8-0.30.80.61.01.31.30.50.40.80.70.2
Latency to leave start box in cocaine runway, F3.33.87.22.2-2.30.11.21.4-0.92.5-1.3-2.5-0.41.12.50.72.62.71.90.61.92.12.62.72.72.01.72.32.11.5
Latency to leave start box in cocaine runway, M2.62.44.4-1.01.20.3-1.7-1.7-0.7-1.61.51.5-0.7-1.6-2.0-1.3-1.2-1.5-1.4-1.4-1.6-2.0-2.1-1.6-1.6-2.0-1.8-2.0-1.9-1.6
Std. dev. time between licks in bursts0.60.91.70.6-0.6-0.10.81.00.01.1-0.8-1.10.01.01.10.61.31.10.70.70.91.11.21.11.11.11.01.31.21.0
Total sessions with >9 infusions2.83.47.00.6-0.8-1.12.22.01.51.0-1.8-1.11.42.42.61.91.01.31.51.71.62.52.21.61.62.52.42.52.31.9
Short access day 1 total inactive lever presses0.60.82.6-0.90.9-1.61.31.41.0-1.0-1.20.91.50.81.10.9-0.9-0.6-0.40.81.10.70.2-0.4-0.40.60.70.40.50.4
Short access day 10 total inactive lever presses0.61.42.9-1.51.4-1.51.61.61.7-1.0-1.71.11.71.00.31.7-1.5-0.9-0.81.40.90.8-0.1-1.1-1.10.60.7-0.30.3-1.3
Short access day 1 total infusions0.81.04.7-0.60.5-0.71.41.22.0-0.3-1.20.31.21.11.11.1-0.6-0.4-0.40.82.21.20.6-0.1-0.11.20.90.70.81.0
Short access day 10 total infusions1.21.53.2-0.30.2-1.21.61.41.30.2-1.4-0.31.31.71.61.60.20.40.41.41.81.61.20.60.61.61.61.41.51.0
Short access total infusions1.31.64.3-0.40.3-1.21.81.51.8-0.0-1.5-0.01.51.71.61.6-0.20.10.21.42.11.71.10.30.31.71.61.31.41.0
Short access day 1 locomotion1.31.64.1-1.11.0-1.71.81.92.0-0.6-1.70.51.81.91.51.7-0.6-0.3-0.31.41.11.30.7-0.0-0.01.31.51.01.10.8
Short access day 10 total locomotion1.12.16.7-1.41.3-2.22.01.91.3-0.6-2.00.61.92.01.22.6-0.7-0.2-0.12.10.81.50.7-0.3-0.31.41.80.81.3-0.8
Short access total locomotion3.84.510.8-0.90.8-2.63.02.92.1-0.0-2.8-0.12.63.22.63.3-0.10.50.72.91.62.71.90.60.62.72.92.12.40.5
One hour access (0.3 mA shock)0.30.41.70.6-0.60.40.3-0.20.40.80.3-0.9-0.30.50.6-0.00.90.70.3-0.10.40.60.70.80.80.60.40.70.31.3
Compulsive drug intake0.40.51.6-0.10.20.3-1.0-0.8-1.1-0.41.00.4-0.7-0.9-0.8-1.0-0.0-0.2-0.2-0.6-1.3-1.2-0.8-0.3-0.3-1.1-0.8-0.6-0.7-0.1
One hour access (shock baseline)1.11.73.30.6-0.7-0.61.61.21.01.0-1.1-1.10.81.71.81.40.91.11.01.11.11.81.71.21.21.81.71.71.51.1
Social response proportion3.03.47.50.2-0.3-2.52.42.70.00.2-2.7-0.22.22.12.32.70.11.11.92.7-0.42.21.90.80.82.12.51.72.5-1.1
Social responses0.40.52.1-0.50.5-1.30.70.9-0.3-0.5-1.00.50.90.60.41.2-0.40.00.11.00.10.40.2-0.1-0.10.40.70.10.6-1.5
Social time2.83.89.9-1.31.2-3.12.82.71.4-0.8-2.90.83.12.62.02.9-1.00.00.73.10.12.11.3-0.1-0.12.12.41.22.1-0.7
Soleus weight0.51.43.10.5-0.6-1.01.51.60.40.7-1.5-0.61.11.21.61.30.40.91.41.80.71.61.50.80.81.51.51.41.50.5
Bone: stiffness0.10.21.00.3-0.20.40.0-0.1-0.20.60.2-0.6-0.7-0.00.0-0.20.50.4-0.6-0.51.00.10.20.40.4-0.1-0.2-0.1-0.3-0.2
Tibialis anterior weight0.82.75.30.6-0.7-1.21.91.90.51.0-1.8-1.01.32.12.21.91.11.41.92.00.02.12.11.41.42.22.32.12.20.9
Time to tail flick, vehicle, before self-admin1.41.54.00.7-0.61.7-1.8-1.7-1.00.31.8-0.3-1.6-1.7-1.4-2.00.4-0.2-0.2-1.5-1.2-1.6-1.0-0.1-0.1-1.4-1.6-0.9-1.40.2
Time to tail flick, vehicle, after self-admin0.30.30.9-0.91.0-0.60.1-0.20.5-0.7-0.10.70.50.3-0.30.4-0.8-0.7-0.80.2-0.7-0.3-0.5-0.7-0.7-0.3-0.1-0.6-0.3-0.9
Time to tail flick, test, before self-admin0.50.52.51.2-1.40.5-0.1-0.1-0.20.70.2-0.7-0.2-0.10.4-0.30.70.51.50.3-1.60.30.60.60.60.40.40.80.50.7
Time to tail flick, test, after self-admin0.10.10.30.2-0.30.00.20.30.6-0.1-0.20.10.3-0.1-0.00.1-0.3-0.20.20.3-0.10.30.1-0.3-0.30.30.1-0.00.0-0.2
Delta time to tail flick, vehicle, before/after SA1.11.12.6-1.51.5-1.61.20.81.4-1.0-1.11.01.61.10.31.5-1.3-0.9-0.91.20.30.7-0.1-0.9-0.90.60.7-0.20.3-0.7
Delta time to tail flick, test, before/after SA0.70.71.9-1.41.3-1.10.70.71.3-1.1-0.61.11.10.60.10.4-1.2-1.0-1.20.40.80.1-0.4-1.0-1.00.10.1-0.4-0.20.1
Tibia length0.41.211.81.2-0.9-0.2-0.5-0.1-3.40.9-0.0-1.1-1.1-0.7-0.00.61.11.40.9-0.40.4-0.10.31.11.1-0.40.2-0.20.5-2.8
Ambulatory time before self-admin0.30.42.1-1.11.0-0.20.20.31.4-0.7-0.10.70.50.5-0.2-0.1-0.7-0.9-0.9-0.0-0.5-0.2-0.5-0.8-0.8-0.1-0.2-0.2-0.40.5
Ambulatory time after self-admin0.00.00.2-0.40.5-0.10.20.20.2-0.0-0.30.0-0.00.2-0.10.3-0.1-0.1-0.4-0.0-0.0-0.0-0.2-0.1-0.1-0.00.0-0.1-0.1-0.3
Bone: tissue strength0.90.94.01.3-1.11.1-0.9-0.7-2.01.10.6-1.1-1.6-1.1-0.3-0.61.11.10.0-1.11.0-0.30.10.90.9-0.5-0.6-0.3-0.2-1.0
Total heroin consumption1.01.24.4-1.81.7-0.70.2-0.02.1-1.50.01.61.10.4-0.3-0.3-1.5-1.7-1.60.30.1-0.5-0.9-1.4-1.4-0.3-0.3-0.6-0.71.3
Bone: trabecular number2.23.79.8-2.93.1-2.20.20.40.4-2.9-0.52.91.4-0.3-1.10.6-2.8-2.4-2.70.40.7-1.2-2.0-2.5-2.5-1.3-0.8-2.1-1.3-2.6
Bone: trabecular spacing1.41.94.41.9-2.01.3-0.0-0.3-0.52.10.3-2.1-0.90.41.00.02.02.01.9-0.00.51.01.51.91.91.10.81.51.11.6
Bone: trabecular thickness1.01.23.7-1.41.5-1.91.21.60.7-1.2-1.61.21.51.00.61.4-1.1-0.7-0.91.51.00.5-0.1-0.7-0.70.40.7-0.10.4-1.0
Bone: trabecular tissue density0.81.13.00.3-0.21.1-1.4-1.4-1.4-0.11.40.1-1.4-1.7-1.3-1.2-0.0-0.1-0.5-1.3-0.2-1.2-1.0-0.3-0.3-1.4-1.4-1.1-1.2-1.2
Water consumed over 24 hours0.20.32.70.8-0.70.0-0.2-0.2-1.00.30.1-0.2-0.1-0.6-0.20.2-0.30.10.8-0.2-1.1-0.2-0.0-0.1-0.1-0.3-0.2-0.5-0.1-1.6
Number of responses in last shaping day1.92.06.8-0.50.4-1.62.02.11.20.0-2.1-0.01.61.71.72.2-0.20.5-0.01.82.61.91.20.40.41.71.71.01.4-0.1