Hub : Genes

Efr3b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Efr3b 0.24 0.07 0.0e+00 0.39 0.39 0.38 0.39 2.1e-45 1.4e-44 3.7e-44 9.7e-45
2 pVTA gene expression Efr3b 0.03 0.02 3.6e-03 0.03 0.04 0.04 0.04 8.8e-04 6.9e-04 3.2e-04 2.7e-04
3 BLA gene expression Efr3b 0.23 0.2 3.2e-08 0.11 0.13 0.13 0.13 1.3e-06 3.5e-07 1.9e-07 2.2e-07
4 NAcc alternative TSS XM_039113097.2 0.01 0.01 9.3e-03 0.01 0.01 0.01 0.01 6.1e-03 7.6e-03 8.1e-03 1.1e-02
5 Adipose gene expression Efr3b 0.1 0.06 4.6e-12 0.07 0.08 0.08 0.08 1.4e-08 6.7e-09 4.8e-09 6.3e-09
6 Brain mRNA stability Efr3b 0.17 0.12 2.7e-12 0.14 0.13 0.12 0.13 9.1e-13 3.6e-12 3.1e-11 3.9e-12
7 BLA mRNA stability Efr3b 0.17 0.12 4.5e-07 0.11 0.12 0.11 0.13 1.9e-06 1.0e-06 1.8e-06 1.5e-07
8 PL alternative TSS XM_039113097.2 0.02 0.02 5.5e-03 0.02 0.02 0.02 0.02 4.2e-03 4.2e-03 4.9e-03 4.0e-03
9 NAcc gene expression Efr3b 0.18 0.03 0.0e+00 0.31 0.33 0.33 0.33 2.5e-48 2.9e-51 4.1e-51 1.8e-51
10 PL alternative TSS NM_001427261.1 0.02 0.02 2.6e-03 0.02 0.02 0.02 0.02 2.4e-03 2.2e-03 1.4e-03 1.8e-03
11 pVTA mRNA stability Efr3b 0.03 0.03 6.1e-03 0.01 0.02 0.01 0.01 2.4e-02 5.1e-03 2.0e-02 2.7e-02
12 OFC mRNA stability Efr3b 0.16 0.12 4.7e-04 0.11 0.11 0.09 0.1 1.7e-03 1.2e-03 3.4e-03 2.1e-03
13 NAcc alternative TSS NM_001427261.1 0.01 0.01 5.9e-03 0.01 0.01 0.01 0.01 4.1e-03 3.8e-03 4.9e-03 6.5e-03
14 PL mRNA stability Efr3b 0.14 0.07 0.0e+00 0.17 0.19 0.19 0.19 1.6e-18 6.6e-20 3.3e-20 2.4e-20
15 Brain gene expression Efr3b 0.21 0.14 1.4e-15 0.17 0.14 0.15 0.16 7.4e-16 2.0e-13 5.9e-14 8.4e-15
16 LHb mRNA stability Efr3b 0.17 0.13 5.6e-04 0.15 0.14 0.15 0.15 2.0e-04 4.4e-04 2.0e-04 2.6e-04
17 NAcc mRNA stability Efr3b 0.09 0.05 0.0e+00 0.12 0.15 0.15 0.15 2.2e-18 1.8e-22 6.4e-22 6.7e-22
18 IC mRNA stability Efr3b 0.07 0.05 3.8e-04 0.04 0.06 0.04 0.04 8.1e-03 1.1e-03 1.1e-02 5.6e-03
19 IC gene expression Efr3b 0.29 0.27 4.0e-09 0.16 0.21 0.22 0.19 3.6e-07 4.1e-09 1.2e-09 1.7e-08
20 BLA alternative TSS XM_039113097.2 0.06 0.05 3.2e-03 0.03 0.03 0.02 0.03 1.1e-02 7.7e-03 4.3e-02 8.3e-03
21 BLA alternative TSS NM_001427261.1 0.07 0.06 2.6e-03 0.03 0.03 0.02 0.03 1.1e-02 6.7e-03 2.8e-02 7.9e-03
22 IL gene expression Efr3b 0.72 0.25 3.1e-15 0.46 0.42 0.46 0.45 1.8e-12 2.3e-11 2.1e-12 3.4e-12
23 IL mRNA stability Efr3b 0.29 0.21 5.0e-05 0.16 0.15 0.15 0.15 1.0e-04 1.7e-04 1.9e-04 1.7e-04
24 LHb gene expression Efr3b 0.2 0.14 2.0e-04 0.14 0.12 0.1 0.1 4.2e-04 1.1e-03 2.8e-03 2.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density3.25.510.92.22.22.2-2.4-3.32.42.5-2.32.32.52.32.22.32.51.92.22.22.32.1-2.22.31.82.72.7
Area under the delay curve0.10.11.40.30.20.2-0.31.20.10.0-0.10.10.10.00.10.1-0.1-0.00.10.10.10.3-0.10.10.1-0.2-0.1
BMI with tail2.89.812.9-3.4-3.3-3.43.22.5-3.1-3.13.0-3.4-3.1-3.1-3.2-3.1-3.0-3.6-3.2-3.1-3.0-3.22.9-2.9-3.3-2.8-2.9
BMI without tail3.09.310.7-3.2-3.2-3.23.02.9-3.0-3.03.0-3.1-3.1-3.0-3.0-3.0-3.2-3.3-3.0-2.9-2.9-3.22.8-2.8-3.0-3.1-3.1
Body weight2.611.415.1-3.8-3.8-3.83.61.6-3.2-3.23.2-3.8-3.2-3.4-3.5-3.5-3.2-3.9-3.5-3.5-3.3-3.63.2-3.2-3.6-3.0-2.7
Weight adjusted by age0.60.91.7-1.3-1.2-1.31.30.4-1.0-1.10.8-1.2-0.9-0.9-0.8-0.8-1.1-1.0-0.8-0.7-0.6-0.70.5-0.5-1.1-1.2-0.6
Bone surface0.51.02.10.91.00.9-0.9-1.30.90.9-0.90.91.00.90.90.91.20.61.00.90.91.1-0.90.90.91.41.3
Bone volume1.73.06.71.71.71.6-1.7-2.61.71.8-1.71.61.81.61.61.61.91.31.61.61.61.7-1.61.61.52.12.0
Breakpoint value in progressive ratio session0.70.81.50.90.80.9-0.8-1.20.90.9-0.80.90.80.91.00.90.91.01.01.00.90.8-0.90.91.00.90.8
Number of licking bursts1.22.03.5-1.3-1.4-1.31.40.4-1.6-1.31.4-1.4-1.4-1.5-1.5-1.5-1.6-1.9-1.5-1.5-1.4-1.01.4-1.3-1.7-1.5-1.3
Context. condit. distance diff. score0.20.20.30.60.50.5-0.4-0.30.50.4-0.30.50.40.50.50.50.50.40.60.50.50.4-0.50.50.40.50.5
Locomotion velocity, session 10.20.20.3-0.3-0.2-0.30.30.5-0.5-0.50.5-0.3-0.4-0.5-0.5-0.5-0.2-0.6-0.5-0.5-0.5-0.20.6-0.6-0.4-0.1-0.2
Locomotion distance, session 10.91.11.61.31.21.2-1.1-1.11.21.2-1.31.01.21.11.01.01.20.70.80.91.01.2-0.90.90.71.11.1
Locomotion velocity, session 20.40.51.7-0.7-0.8-0.80.70.8-0.8-0.70.7-0.9-0.7-0.7-0.6-0.7-0.7-1.3-0.4-0.6-0.6-0.40.5-0.5-0.5-0.5-0.6
Locomotion distance, session 20.00.00.10.20.20.1-0.20.20.40.2-0.2-0.00.20.10.0-0.00.0-0.3-0.1-0.1-0.00.30.1-0.10.1-0.2-0.1
Locomotion velocity, session 30.00.00.1-0.1-0.0-0.10.0-0.20.20.20.0-0.0-0.0-0.0-0.00.0-0.0-0.1-0.1-0.00.0-0.3-0.10.1-0.30.1-0.1
Locomotion distance, session 30.00.00.1-0.1-0.1-0.10.10.1-0.00.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.2-0.2-0.30.2-0.2-0.20.0-0.1
Stereotopy head waving bouts, day 32.32.74.31.51.61.6-1.6-1.21.71.5-1.51.71.61.71.71.71.72.11.81.71.71.7-1.61.61.71.61.7
Stereotopy head waving duration, day 30.30.40.90.50.50.6-0.5-0.40.60.4-0.40.70.50.60.60.60.60.90.70.70.60.7-0.70.70.60.60.6
Locomotion velocity, session 70.00.00.1-0.0-0.3-0.10.0-0.0-0.00.2-0.1-0.20.0-0.1-0.1-0.1-0.1-0.2-0.1-0.1-0.1-0.30.0-0.0-0.1-0.1-0.2
Locomotion distance, session 71.01.32.8-1.0-1.2-1.01.01.2-1.0-0.81.0-1.1-1.2-1.1-1.0-1.1-1.5-0.9-1.2-1.0-1.1-1.41.0-1.0-0.9-1.7-1.6
Stereotopy head waving bouts, day 70.00.00.20.00.20.1-0.10.10.30.10.10.20.00.0-0.00.10.1-0.0-0.2-0.00.0-0.0-0.00.0-0.40.30.3
Stereotopy head waving duration, day 70.30.30.70.40.60.5-0.5-0.40.70.5-0.50.60.50.50.50.60.70.50.40.50.60.6-0.70.70.00.80.8
Locomotion velocity, session 80.50.61.50.50.50.5-0.5-0.70.50.8-0.60.60.60.70.70.71.10.51.00.70.70.6-0.70.71.01.21.1
Locomotion distance, session 80.81.12.21.51.31.3-1.3-0.81.41.3-1.01.20.91.11.01.00.71.00.91.00.90.9-0.90.91.20.50.5
Degree of sensitization distance1.41.42.6-1.1-1.2-1.11.11.6-1.2-1.21.1-1.2-1.2-1.1-1.1-1.1-1.4-1.0-1.2-1.1-1.1-1.11.0-1.0-1.1-1.6-1.5
Degree of sensitization stereotypy0.40.41.2-0.6-0.4-0.60.60.8-0.2-0.50.6-0.5-0.6-0.6-0.7-0.6-0.6-0.9-0.9-0.7-0.6-0.70.5-0.5-1.1-0.6-0.5
Conditioned locomotion2.12.43.91.61.51.6-1.7-2.01.61.4-1.61.61.61.61.71.71.11.31.51.71.81.7-1.81.81.20.91.1
Cocaine response after cond. corrected0.10.11.30.30.30.3-0.31.10.20.1-0.30.30.30.30.30.30.50.20.20.30.40.4-0.40.4-0.10.30.3
Cocaine response after cond. not corrected0.50.61.10.80.80.8-0.80.10.70.7-0.80.90.80.80.80.80.90.80.70.80.81.0-0.80.80.50.70.8
Cocaine response before conditioning1.92.34.61.41.41.5-1.3-2.11.31.5-1.41.51.51.51.61.51.41.51.71.61.61.9-1.51.51.61.21.4
Saline control response1.41.82.51.31.31.3-1.4-1.01.31.2-1.31.31.41.31.31.31.51.31.41.31.31.4-1.31.31.21.51.6
Bone: connectivity density1.72.66.61.41.41.4-1.6-2.61.71.7-1.61.51.71.61.61.61.81.41.51.51.61.3-1.61.61.21.81.9
Bone: cortical apparent density0.10.10.50.20.20.2-0.20.60.30.1-0.30.30.40.40.40.30.40.50.50.40.30.4-0.20.20.70.40.5
Bone: cortical area0.00.00.10.0-0.1-0.00.0-0.1-0.0-0.0-0.0-0.10.0-0.1-0.2-0.1-0.0-0.3-0.2-0.2-0.10.00.1-0.1-0.40.20.1
Bone: cortical porosity2.72.94.31.51.41.5-1.5-1.81.51.6-1.71.51.81.71.71.72.01.41.91.81.81.9-1.91.91.42.02.1
Bone: cortical porosity2.42.64.01.41.31.4-1.4-1.81.31.6-1.61.41.71.61.61.61.91.21.81.71.71.7-1.81.81.41.92.0
Bone: cortical thickness0.10.20.3-0.4-0.5-0.40.40.4-0.4-0.40.3-0.4-0.4-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.50.6-0.6-0.5-0.4-0.4
Bone: cortical thickness0.50.60.90.80.70.8-0.80.40.70.7-1.00.70.90.80.70.71.00.70.80.70.70.9-0.70.70.70.80.9
Bone: cortical tissue density0.10.10.50.10.10.1-0.10.70.20.0-0.20.20.30.30.30.20.40.40.40.30.20.3-0.10.10.60.40.5
Condit. Reinf. active minus inactive responses2.73.04.5-1.7-1.9-1.81.82.1-1.8-1.81.7-1.8-1.6-1.8-1.8-1.8-1.5-1.8-1.6-1.8-1.7-1.61.7-1.7-1.7-1.4-1.3
Condit. Reinf. active-inactive response ratio2.62.86.3-1.8-2.0-1.81.92.5-2.0-1.81.8-1.7-1.6-1.7-1.7-1.7-1.2-1.3-1.4-1.6-1.7-1.71.7-1.7-1.4-1.0-1.0
Condit. Reinf. active responses0.20.30.6-0.5-0.6-0.50.50.6-0.4-0.50.4-0.6-0.4-0.5-0.6-0.6-0.4-0.8-0.5-0.6-0.5-0.40.5-0.5-0.6-0.4-0.4
Condit. Reinf. inactive responses1.61.95.01.51.61.4-1.5-2.21.71.5-1.61.31.41.41.31.31.20.91.11.31.31.4-1.31.31.10.91.0
Incentive salience index mean0.50.61.4-0.8-1.0-0.90.80.8-0.8-0.70.7-0.9-0.6-0.8-0.8-0.8-0.4-1.2-0.7-0.9-0.7-0.60.7-0.7-1.1-0.2-0.2
Condit. Reinf. lever presses0.81.11.81.00.90.9-1.0-1.31.11.1-1.10.81.21.00.91.01.20.20.90.91.11.2-1.11.20.41.41.3
Condit. Reinf. active minus inactive responses0.70.91.30.90.90.9-0.9-0.90.90.9-1.00.91.01.01.01.00.91.10.91.01.11.1-1.11.00.80.70.9
Condit. Reinf. active-inactive response ratio0.30.41.70.50.40.5-0.5-1.30.50.7-0.60.50.60.60.60.60.50.40.50.60.70.7-0.70.70.10.60.7
Condit. Reinf. active responses0.40.61.30.80.90.9-0.8-0.20.80.7-0.90.70.90.80.80.80.80.90.60.80.81.1-0.80.80.50.50.7
Condit. Reinf. inactive responses0.20.20.70.60.60.6-0.50.60.50.3-0.50.40.50.40.40.40.50.50.20.30.40.8-0.40.40.10.30.2
Condit. Reinf. lever presses0.91.21.81.01.21.1-1.0-1.01.11.1-1.11.11.11.11.11.21.11.41.11.21.11.3-1.11.11.01.01.0
Condit. Reinf. lever reinforcers received0.40.51.10.70.70.7-0.6-0.20.70.6-0.80.60.80.80.80.80.80.90.70.80.81.1-0.80.80.50.50.7
Conditioned reinforcement - actives3.66.17.42.22.22.3-2.3-1.92.52.5-2.62.52.62.62.62.52.72.72.72.62.52.1-2.42.42.72.52.7
Conditioned reinforcement - inactives6.39.211.53.03.03.0-3.2-2.12.93.1-3.43.23.33.13.03.13.33.33.03.03.02.5-3.03.02.73.23.2
Conditioned locomotion3.03.96.91.61.71.8-1.6-1.31.91.9-2.01.62.12.02.01.82.42.02.42.01.81.7-1.81.72.62.32.5
Patch foraging indifference point 0 sec0.20.31.4-0.6-0.5-0.60.3-1.2-0.2-0.00.5-0.4-0.6-0.5-0.5-0.5-0.4-0.3-0.4-0.5-0.6-0.90.7-0.70.2-0.2-0.6
Patch foraging indifference point AUC0.00.10.40.30.30.2-0.20.50.0-0.20.10.2-0.2-0.1-0.10.0-0.20.0-0.3-0.10.00.3-0.10.1-0.7-0.4-0.3
Delay disc. indifference point, 0s delay0.30.33.2-0.4-0.3-0.30.21.8-0.4-0.40.5-0.3-0.5-0.5-0.5-0.5-0.6-0.3-0.6-0.5-0.6-0.50.6-0.6-0.3-0.6-0.7
Delay disc. indifference point, 16s delay0.00.00.60.10.10.1-0.00.8-0.2-0.30.1-0.0-0.0-0.1-0.1-0.1-0.2-0.1-0.1-0.1-0.10.40.1-0.1-0.2-0.30.1
Delay disc. indifference point, 2s delay0.10.12.2-0.1-0.0-0.1-0.11.5-0.2-0.10.2-0.2-0.2-0.1-0.1-0.20.0-0.20.2-0.1-0.2-0.20.2-0.20.60.1-0.1
Delay disc. indifference point, 24s delay2.83.24.21.91.91.9-1.9-1.52.11.9-1.91.61.91.81.71.71.81.31.71.71.81.9-1.81.81.41.72.1
Delay disc. indifference point, 4s delay0.20.21.3-0.1-0.2-0.10.01.1-0.5-0.30.2-0.2-0.3-0.3-0.2-0.2-0.60.0-0.1-0.2-0.3-0.20.3-0.30.3-0.8-0.8
Delay disc. indifference point, 8s delay0.00.10.80.20.20.1-0.30.90.20.2-0.10.00.10.10.10.1-0.10.00.10.10.10.2-0.20.20.2-0.1-0.1
Indifference point function ln k1.73.07.31.51.51.6-1.7-2.71.72.1-1.71.61.71.71.71.71.71.71.71.71.71.4-1.71.71.71.71.7
Indifference point function log k1.73.07.31.51.51.6-1.7-2.71.72.1-1.71.61.71.71.71.71.71.71.71.71.71.4-1.71.71.71.71.7
Patch foraging total patch changes 0 sec0.10.31.2-0.5-0.5-0.50.3-1.1-0.2-0.10.5-0.4-0.5-0.5-0.5-0.5-0.5-0.3-0.5-0.5-0.6-0.80.7-0.70.3-0.3-0.7
Patch foraging total patch changes 12 sec1.62.02.8-1.5-1.5-1.51.41.2-1.1-1.61.4-1.4-1.5-1.4-1.4-1.4-1.5-1.5-1.6-1.4-1.3-1.31.2-1.2-1.7-1.5-1.5
Patch foraging total patch changes 18 sec0.60.91.2-0.9-0.8-1.01.00.9-0.9-1.01.0-0.8-1.0-0.9-0.9-0.9-1.0-0.7-0.9-0.9-1.0-0.81.0-1.0-0.6-1.1-0.9
Patch foraging total patch changes 24 sec0.81.42.3-0.9-0.9-1.11.10.7-1.0-1.21.2-1.0-1.3-1.2-1.2-1.2-1.3-1.3-1.4-1.2-1.2-1.01.2-1.2-0.9-1.4-1.5
Patch foraging total patch changes 6 sec1.31.92.8-1.3-1.3-1.41.20.4-1.1-1.21.5-1.3-1.5-1.5-1.5-1.5-1.5-1.2-1.6-1.5-1.5-1.61.5-1.5-1.3-1.4-1.7
Patch foraging time to switch 0 sec0.71.44.2-1.4-1.3-1.31.32.0-1.3-1.41.3-1.2-1.2-1.1-1.1-1.1-1.2-1.0-0.9-1.0-1.1-1.11.1-1.1-0.8-1.2-1.0
Patch foraging water rate 0 sec2.24.79.52.32.32.2-2.3-3.12.52.6-2.22.22.12.22.12.02.12.12.02.01.91.8-1.81.82.21.91.8
Patch foraging water rate 12 sec0.00.00.60.00.00.0-0.1-0.70.30.2-0.00.00.1-0.0-0.1-0.10.0-0.1-0.1-0.1-0.1-0.10.2-0.2-0.00.10.1
Patch foraging water rate 18 sec2.43.85.22.12.22.1-2.2-2.02.32.2-2.12.22.02.01.91.91.92.11.71.71.71.6-1.61.62.01.71.8
Patch foraging water rate 24 sec0.10.20.6-0.5-0.6-0.50.5-0.8-0.3-0.10.3-0.5-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.3-0.4-0.50.4-0.4-0.3-0.3-0.2
Patch foraging water rate 6 sec0.91.32.01.21.21.2-1.3-1.21.31.4-1.21.21.11.11.11.11.01.41.01.00.90.9-0.80.81.40.80.9
Seeking ratio, delayed vs. immediate footshock0.40.52.8-0.8-0.8-0.80.81.7-0.9-0.80.6-0.7-0.5-0.6-0.6-0.6-0.5-0.5-0.3-0.5-0.5-0.40.5-0.5-0.4-0.3-0.2
Distance traveled before self-admin0.10.10.20.30.40.4-0.3-0.30.30.2-0.50.20.40.20.20.2-0.10.30.10.20.20.4-0.30.3-0.2-0.20.2
Distance traveled after self-admin0.30.30.7-0.3-0.4-0.30.50.4-0.5-0.50.6-0.5-0.7-0.6-0.6-0.7-0.6-0.4-0.7-0.6-0.8-0.80.8-0.8-0.3-0.6-0.7
Extensor digitorum longus weight2.59.714.43.03.03.0-3.0-3.83.03.2-3.22.93.33.13.03.13.42.72.93.03.13.2-3.13.12.33.53.5
Bone: elastic displacement1.92.23.41.41.51.5-1.4-1.41.41.4-1.41.51.41.51.51.51.71.81.51.51.41.4-1.41.41.41.81.8
Bone: elastic work1.11.53.01.21.21.2-1.2-1.01.21.3-1.11.31.11.21.11.11.41.41.31.11.00.8-0.90.91.41.71.6
Bone: endosteal estimation0.30.51.20.91.00.8-0.9-0.80.70.8-0.70.70.70.60.60.60.90.50.60.60.60.7-0.60.60.51.10.8
Bone: endosteal perimeter0.00.10.4-0.00.0-0.00.1-0.6-0.10.10.0-0.00.1-0.0-0.10.00.3-0.3-0.0-0.10.10.1-0.10.1-0.40.60.4
Epididymis fat weight19.968.378.6-8.8-8.9-8.88.86.6-8.4-8.58.3-8.8-8.3-8.4-8.4-8.4-8.1-8.6-8.1-8.3-8.2-8.68.1-8.1-7.7-7.6-7.2
Delta time in closed arm before/after self-admin0.10.10.3-0.2-0.2-0.10.1-0.50.0-0.10.2-0.1-0.2-0.2-0.1-0.1-0.40.3-0.1-0.1-0.2-0.40.1-0.1-0.0-0.4-0.4
Delta time in open arm before/after self-admin0.10.10.8-0.2-0.3-0.30.10.4-0.3-0.10.1-0.40.0-0.3-0.4-0.3-0.1-0.9-0.5-0.4-0.20.10.1-0.1-0.9-0.10.1
Diff in mean of infusions in LGA sessions0.50.63.1-0.8-0.8-0.80.91.8-0.9-0.80.7-0.8-0.7-0.7-0.7-0.6-0.3-1.3-0.6-0.7-0.5-0.70.5-0.4-1.0-0.1-0.2
Delay discount exponential model param0.10.20.8-0.5-0.4-0.40.6-0.9-0.3-0.30.4-0.3-0.4-0.3-0.3-0.3-0.2-0.2-0.4-0.3-0.3-0.50.4-0.4-0.4-0.1-0.2
Extinction: sum of active levers before priming0.10.11.5-0.10.1-0.1-0.1-1.20.20.3-0.20.20.30.20.30.30.1-0.00.40.40.40.2-0.50.50.10.10.3
Active lever presses in extinction session 61.41.42.90.90.80.9-1.0-1.71.41.2-1.30.91.31.11.01.21.40.50.81.01.31.0-1.41.5-0.21.61.6
Bone: final force0.10.10.4-0.3-0.5-0.40.30.4-0.2-0.20.2-0.3-0.1-0.3-0.3-0.30.2-0.6-0.2-0.3-0.2-0.20.2-0.1-0.60.60.3
Bone: final moment0.00.10.5-0.2-0.3-0.30.20.3-0.1-0.10.2-0.2-0.0-0.2-0.2-0.20.2-0.3-0.1-0.2-0.1-0.20.1-0.1-0.40.70.3
Food consumed during 24 hour testing period0.00.10.40.50.40.4-0.40.60.30.3-0.20.30.10.10.10.1-0.00.1-0.20.00.00.1-0.00.00.0-0.1-0.3
Glucose1.11.74.6-1.3-1.2-1.31.42.2-1.5-1.41.4-1.2-1.4-1.3-1.2-1.2-1.2-0.8-1.3-1.2-1.2-1.31.2-1.2-1.4-1.1-1.1
Heart weight1.21.83.0-1.3-1.1-1.31.31.7-1.4-1.31.4-1.3-1.5-1.4-1.3-1.3-1.5-1.2-1.3-1.3-1.4-1.51.4-1.4-0.7-1.6-1.6
Delay discount hyperbolic model param0.10.11.4-0.3-0.2-0.20.3-1.2-0.0-0.10.1-0.1-0.1-0.0-0.1-0.10.0-0.0-0.2-0.1-0.1-0.30.1-0.1-0.30.10.1
Intermittent access intake day 1-15 change1.53.05.71.91.92.0-1.9-2.01.61.6-1.62.01.61.81.71.71.62.11.81.71.41.5-1.31.22.41.31.6
Intermittent access intake escalation1.02.14.81.61.71.7-1.6-1.91.31.3-1.31.71.21.41.41.31.21.91.41.41.11.1-0.90.92.20.91.2
Intermittent access intake escalation 20.91.13.01.21.31.3-1.3-1.20.70.9-0.91.30.91.01.00.90.71.71.00.90.60.6-0.40.41.70.50.7
Intermitt. access day 1 inactive lever presses0.31.32.91.11.01.0-1.3-1.71.41.3-1.41.01.41.11.11.11.00.60.91.01.20.6-1.31.40.31.11.2
Intermitt. access day 15 inactive lever presses0.51.01.60.80.80.8-1.00.20.80.8-1.01.01.11.01.01.11.11.01.01.11.21.0-1.21.30.21.21.3
Intermitt. access escalation Index4.05.67.8-2.2-2.2-2.12.52.7-2.7-2.62.5-2.1-2.7-2.4-2.2-2.3-2.6-1.4-2.2-2.2-2.4-2.22.5-2.5-1.4-2.7-2.8
Intermittent access day 1 total infusions1.01.72.81.31.21.2-1.2-0.41.41.3-1.41.31.31.31.31.41.31.11.31.31.61.2-1.71.70.71.21.0
Intermittent access day 15 total infusions2.43.54.32.12.02.1-2.0-1.41.81.8-1.92.11.91.92.02.01.72.02.01.91.91.8-1.81.82.01.41.7
Intermittent access terminal intake (last 3 days)3.95.16.22.52.52.5-2.4-1.42.32.2-2.32.42.32.32.32.32.22.32.42.32.22.1-2.22.22.42.02.0
Intermittent access total infusions3.54.25.42.01.92.0-2.0-2.02.32.1-2.21.92.12.12.12.12.11.82.12.12.21.7-2.22.21.71.92.0
Intermittent access day 1 locomotion2.43.04.01.91.91.9-1.9-0.71.81.7-2.01.71.91.81.71.81.81.51.71.71.81.6-1.91.91.51.61.5
Intermittent access day 15 total locomotion0.30.51.10.80.80.8-0.70.11.00.8-0.80.70.70.70.60.60.70.60.70.60.50.3-0.50.51.00.70.6
Intermittent access total locomotion2.02.43.91.71.61.6-1.6-1.42.01.6-1.81.51.61.61.51.51.61.31.51.51.51.1-1.51.51.61.41.5
Intermittent access standard deviation1.43.04.12.02.02.0-2.0-1.51.81.9-1.81.81.81.81.71.71.81.41.61.61.71.7-1.61.61.41.71.7
Left kidney weight0.00.21.3-0.0-0.3-0.1-0.0-1.10.10.2-0.4-0.20.40.20.20.30.4-0.50.20.30.50.6-0.70.7-0.80.40.7
Right kidney weight0.31.54.0-1.6-1.8-1.61.40.4-1.3-1.31.0-1.6-1.0-1.2-1.2-1.1-0.7-1.8-1.0-1.1-0.9-0.80.8-0.7-2.0-0.5-0.3
Cocaine induced anxiety0.10.21.00.20.30.3-0.1-0.70.30.3-0.10.60.20.50.50.50.51.00.50.50.40.4-0.30.30.60.50.4
Post-drug Anxiety1.21.31.7-1.0-1.1-1.11.20.7-1.0-1.01.3-1.0-1.3-1.2-1.2-1.2-1.3-1.0-1.3-1.2-1.2-1.21.2-1.2-1.2-1.3-1.2
Baseline Anxiety3.43.94.9-1.7-1.7-1.81.92.0-1.8-1.81.9-1.9-2.0-2.0-2.0-2.0-2.1-2.2-2.2-2.1-2.0-1.82.0-2.0-2.0-2.2-2.1
Tail length0.10.30.80.50.50.6-0.4-0.90.70.6-0.50.70.50.50.50.50.50.90.40.50.40.5-0.30.30.30.40.7
Length with tail0.10.31.8-0.7-0.8-0.70.7-1.3-0.1-0.20.2-0.7-0.1-0.4-0.5-0.5-0.1-0.6-0.4-0.5-0.4-0.40.4-0.4-0.70.10.5
Length without tail0.10.33.8-0.4-0.6-0.50.3-1.90.20.2-0.3-0.60.3-0.0-0.2-0.20.4-0.8-0.1-0.20.0-0.2-0.10.1-0.70.60.8
Times rat made contact with spout1.01.22.31.11.11.1-1.2-0.80.91.0-1.11.11.31.11.01.01.20.71.11.01.01.4-1.01.01.01.31.5
Lifetime Intake3.84.65.72.12.02.1-2.1-2.02.42.2-2.32.02.22.22.22.22.21.92.22.22.31.8-2.32.31.72.12.1
Liver weight, left1.82.94.2-1.9-1.8-1.91.81.7-1.8-2.11.9-1.6-1.8-1.8-1.8-1.7-1.4-1.5-1.6-1.7-1.8-1.71.8-1.8-1.6-1.1-1.0
Liver weight, right3.35.87.9-2.6-2.5-2.62.52.3-2.4-2.52.4-2.5-2.4-2.5-2.5-2.5-2.1-2.8-2.4-2.5-2.4-2.42.4-2.3-2.5-1.7-1.7
Locomotor activity1.42.15.5-1.7-1.8-1.71.61.5-1.4-1.41.4-1.6-1.2-1.5-1.6-1.4-1.1-1.8-1.6-1.6-1.2-1.01.2-1.1-2.3-0.7-0.6
Locomotor testing distance0.91.63.8-1.4-1.5-1.41.41.6-1.4-1.31.3-1.3-1.0-1.3-1.3-1.2-1.0-1.6-1.3-1.3-1.0-0.70.9-0.9-2.0-0.8-0.6
Locomotor testing rearing0.10.10.5-0.2-0.4-0.20.1-0.20.10.2-0.2-0.20.40.10.10.20.2-0.50.20.20.40.3-0.50.5-0.70.30.7
Locomotion in novel chamber0.50.72.8-1.0-1.1-1.11.00.6-0.5-0.70.7-1.1-0.4-0.8-0.8-0.8-0.4-1.5-0.8-0.8-0.5-0.30.4-0.4-1.7-0.10.1
Locomotion in novel chamber post-restriction1.42.33.3-1.3-1.2-1.31.31.8-1.7-1.61.6-1.3-1.6-1.5-1.5-1.5-1.6-1.2-1.5-1.5-1.7-1.21.7-1.8-0.9-1.7-1.7
Fecal boli incidents, locomotor time 12.73.95.42.12.12.1-2.3-0.72.02.2-2.12.02.02.02.02.02.02.02.02.02.01.9-1.91.91.91.91.6
Change in fecal boli incidents, locomotor task4.54.47.4-2.7-2.4-2.52.50.4-2.1-2.22.3-2.0-2.3-2.1-1.9-2.0-2.3-1.4-1.7-1.8-2.1-2.52.1-2.2-1.0-2.3-2.2
Time >=10cm from walls, locomotor time 10.30.40.80.30.40.4-0.5-0.90.70.5-0.70.40.60.70.60.60.40.90.70.70.70.4-0.60.60.70.20.5
Bouts of movement, locomotor time 10.20.30.80.90.70.8-0.9-0.20.80.8-0.70.70.40.40.40.4-0.20.50.20.30.30.1-0.30.30.6-0.4-0.4
Total resting periods, locomotor time 10.30.30.80.90.70.8-0.9-0.40.80.8-0.70.70.40.50.50.4-0.10.60.20.40.30.1-0.30.30.6-0.4-0.4
Rest time, locomotor task time 10.10.10.9-0.00.10.1-0.00.50.30.00.20.0-0.3-0.1-0.1-0.2-0.50.7-0.3-0.1-0.3-0.60.3-0.30.2-0.7-0.9
Distance moved, locomotor task time 10.30.51.4-0.8-0.8-0.80.80.8-0.9-0.80.6-0.8-0.4-0.6-0.7-0.6-0.0-1.2-0.5-0.7-0.5-0.30.5-0.4-1.00.30.5
Vertical activity count, locomotor time 10.00.10.3-0.2-0.2-0.20.40.1-0.5-0.40.3-0.2-0.1-0.2-0.2-0.20.4-0.50.1-0.2-0.20.40.2-0.20.00.50.5
Time >=10cm from walls, locomotor time 21.01.53.00.81.00.9-0.9-1.01.00.9-1.01.11.21.31.41.31.21.71.61.51.31.0-1.31.31.61.11.6
Bouts of movement, locomotor time 20.20.31.70.30.10.3-0.41.3-0.20.1-0.10.1-0.2-0.2-0.2-0.2-0.7-0.3-0.3-0.3-0.4-0.60.4-0.40.5-1.1-1.0
Total resting periods, locomotor time 20.10.31.40.30.00.2-0.31.2-0.20.10.10.0-0.3-0.2-0.2-0.3-0.8-0.2-0.4-0.3-0.4-0.60.4-0.50.3-1.1-1.0
Rest time, locomotor task time 20.10.10.80.40.20.3-0.3-0.90.30.3-0.20.10.10.10.10.1-0.00.2-0.10.10.10.2-0.10.1-0.1-0.1-0.2
Distance moved, locomotor task time 20.10.10.6-0.4-0.1-0.30.30.7-0.1-0.20.2-0.1-0.0-0.0-0.0-0.00.50.00.30.0-0.0-0.30.0-0.00.20.80.8
Vertical activity count, locomotor time 20.10.20.9-0.20.0-0.10.3-0.2-0.0-0.10.20.2-0.00.30.40.30.70.40.70.50.30.2-0.20.20.90.90.5
Light reinforcement 10.40.91.71.01.01.1-1.1-0.50.70.8-1.01.11.00.90.91.00.91.20.80.91.01.3-1.01.00.60.60.8
Light reinforcement 21.42.23.91.51.61.6-1.6-1.01.01.0-1.41.71.51.51.61.51.32.01.71.61.41.7-1.31.31.91.01.2
Bone: marrow area0.20.51.30.80.90.8-0.8-0.70.70.8-0.60.70.70.60.60.60.90.50.60.60.60.7-0.60.60.51.10.9
Bone: maximum diameter0.10.10.50.40.40.3-0.4-0.70.30.4-0.30.30.30.20.20.20.40.10.10.10.20.2-0.20.20.00.60.4
Bone: maximum force0.00.10.70.1-0.10.0-0.20.30.10.2-0.20.10.20.10.00.10.4-0.20.10.00.10.1-0.10.2-0.20.80.4
Bone: maximum moment0.10.10.80.20.10.2-0.30.20.30.3-0.20.20.30.20.20.20.50.10.20.10.20.2-0.20.2-0.00.90.5
Mean time between licks in bursts0.71.78.5-0.9-1.0-1.01.02.9-1.0-1.11.2-1.1-1.3-1.2-1.2-1.2-1.2-1.3-1.3-1.3-1.3-1.41.3-1.3-1.0-1.1-1.3
Mean num. licks in bursts2.13.34.61.71.81.8-1.9-0.62.01.6-1.81.91.81.91.81.82.02.21.91.81.71.6-1.61.62.12.01.9
Cd content in liver0.40.52.7-0.7-0.8-0.70.71.7-0.8-0.80.5-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.40.5-0.5-0.6-0.8-0.5
Co content in liver3.43.95.11.81.71.8-1.8-2.02.01.9-2.11.82.12.12.12.12.11.52.12.12.22.2-2.32.31.51.91.9
Cu content in liver0.10.10.9-0.2-0.2-0.20.20.9-0.3-0.40.0-0.3-0.0-0.1-0.00.0-0.3-0.5-0.10.10.20.4-0.30.3-0.5-0.6-0.5
Fe content in liver2.32.83.81.71.61.6-1.7-1.61.71.7-1.81.51.81.71.61.61.81.41.61.61.61.7-1.61.61.41.91.8
K content in liver0.80.71.4-0.9-0.9-0.90.90.3-0.7-0.90.8-0.9-0.9-0.9-0.8-0.8-1.0-0.9-0.8-0.8-0.7-0.60.6-0.6-1.1-1.2-1.1
Mg content in liver0.10.10.7-0.2-0.1-0.20.20.0-0.1-0.30.2-0.2-0.3-0.2-0.1-0.1-0.50.0-0.2-0.1-0.1-0.10.1-0.1-0.2-0.8-0.7
Mn content in liver0.60.61.2-0.8-0.8-0.80.80.2-0.7-0.80.8-0.8-0.9-0.8-0.8-0.8-1.0-0.6-0.7-0.7-0.8-0.90.8-0.8-0.3-1.1-1.0
Na content in liver3.23.45.71.81.91.9-1.8-2.42.01.9-1.72.01.81.81.81.91.81.91.61.81.81.7-1.81.81.42.01.9
Rb content in liver0.30.40.6-0.8-0.7-0.70.7-0.2-0.6-0.60.6-0.7-0.6-0.5-0.5-0.5-0.7-0.5-0.5-0.5-0.5-0.70.5-0.5-0.5-0.7-0.8
Se content in liver0.30.31.3-0.7-0.7-0.60.71.1-0.7-0.80.5-0.6-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.4-0.4-0.20.4-0.4-0.4-0.4-0.5
Sr content in liver0.20.20.90.40.40.4-0.4-0.20.40.4-0.40.50.40.40.50.40.40.50.70.50.30.3-0.30.30.90.50.4
Zn content in liver1.92.14.4-1.4-1.4-1.41.42.1-1.4-1.71.3-1.4-1.4-1.3-1.3-1.2-1.6-1.5-1.4-1.2-1.1-1.01.0-1.0-1.6-2.0-1.8
Bone: minimum diameter0.91.62.6-1.3-1.3-1.31.31.1-1.3-1.21.2-1.3-1.2-1.3-1.3-1.3-1.1-1.6-1.3-1.3-1.2-1.11.1-1.1-1.5-0.9-1.1
Time in familiar zone, hab. session 11.61.52.5-1.3-1.3-1.31.31.6-1.3-1.21.2-1.4-1.3-1.2-1.2-1.2-1.2-1.4-1.1-1.1-1.1-1.21.1-1.1-1.0-1.2-1.2
Time in novel zone, hab. session 10.30.30.7-0.8-0.8-0.80.70.4-0.5-0.60.6-0.6-0.5-0.5-0.6-0.6-0.3-0.4-0.4-0.5-0.6-0.60.6-0.6-0.3-0.2-0.1
Total zone transitions, hab. session 10.71.02.41.21.11.2-1.2-1.21.61.3-1.11.01.00.90.80.81.00.70.60.70.80.8-0.80.80.41.11.0
Total locomotion distance, hab. session 11.31.93.31.51.41.4-1.5-1.31.81.6-1.51.41.41.41.31.31.51.21.11.21.31.3-1.21.21.01.31.4
Locomotion velocity, hab. session 12.53.55.52.12.02.0-2.1-1.92.32.1-2.02.01.91.91.81.81.91.71.51.71.71.8-1.71.71.41.71.7
Time in familiar zone, hab. session 20.40.44.8-0.5-0.5-0.40.52.2-0.8-0.60.7-0.5-0.6-0.5-0.5-0.5-0.4-0.3-0.3-0.4-0.6-0.50.6-0.60.1-0.2-0.4
Time in novel zone, hab. session 20.20.20.6-0.7-0.7-0.70.6-0.5-0.4-0.50.4-0.6-0.3-0.4-0.4-0.4-0.3-0.6-0.3-0.4-0.3-0.30.3-0.3-0.6-0.5-0.2
Total zone transitions, hab. session 20.10.20.50.70.60.6-0.5-0.40.70.6-0.40.30.30.30.10.10.5-0.10.0-0.00.00.30.0-0.00.10.70.5
Total locomotion distance, hab. session 20.10.10.30.40.40.3-0.3-0.20.50.4-0.20.20.20.1-0.0-0.00.4-0.1-0.1-0.2-0.10.20.2-0.2-0.00.50.4
Locomotion velocity, hab. session 20.10.20.50.60.60.5-0.5-0.30.70.6-0.40.40.40.30.10.20.50.0-0.0-0.00.10.3-0.00.0-0.00.70.6
Novel to familiar place preference ratio0.00.00.2-0.0-0.0-0.0-0.0-0.30.2-0.1-0.10.1-0.1-0.1-0.2-0.2-0.30.0-0.4-0.3-0.3-0.20.3-0.3-0.3-0.2-0.3
Novelty place preference0.20.20.5-0.3-0.4-0.30.3-0.0-0.1-0.40.2-0.2-0.3-0.4-0.5-0.5-0.5-0.3-0.7-0.5-0.5-0.40.6-0.6-0.6-0.5-0.5
Time in novel zone, NPP test0.30.30.6-0.5-0.5-0.50.50.1-0.3-0.60.3-0.5-0.4-0.5-0.6-0.6-0.6-0.5-0.8-0.6-0.6-0.40.6-0.6-0.6-0.5-0.6
Total zone transitions, NPP test0.91.32.01.31.21.2-1.2-0.81.31.3-1.31.01.31.21.11.11.30.60.91.01.21.4-1.21.20.61.31.2
Total locomotion distance, NPP test1.72.33.11.71.71.6-1.6-1.81.71.7-1.71.41.61.51.41.51.51.21.31.41.51.7-1.51.51.01.41.4
Locomotion velocity, NPP test2.63.64.62.12.12.0-2.1-2.12.12.1-2.02.02.01.91.81.91.91.61.51.71.82.0-1.81.81.21.91.9
Intraocular pressure3.85.57.3-2.6-2.5-2.52.51.0-2.2-2.32.5-2.4-2.5-2.3-2.3-2.4-2.5-2.0-2.2-2.2-2.4-2.52.5-2.5-1.6-2.7-2.5
Delta distance traveled before/after self-admin1.31.42.1-0.9-1.1-1.01.11.1-1.3-1.11.4-1.0-1.4-1.2-1.2-1.2-1.0-0.9-1.3-1.3-1.3-1.41.3-1.4-0.9-0.8-1.3
Delta ambulatory time before/after self-admin0.10.10.40.1-0.10.00.10.2-0.3-0.10.5-0.1-0.5-0.3-0.2-0.3-0.1-0.2-0.2-0.3-0.4-0.60.5-0.50.40.0-0.5
Parametrial fat weight26.061.074.5-8.0-8.1-8.17.87.8-8.0-7.88.0-7.9-7.9-8.0-8.0-7.8-7.5-7.8-8.0-7.9-7.6-7.97.5-7.4-8.6-6.8-6.9
Pavlov. Cond. lever latency0.50.61.5-0.8-0.7-0.70.81.2-0.9-0.90.8-0.6-0.9-0.7-0.7-0.7-0.8-0.1-0.6-0.6-0.8-0.80.9-0.9-0.2-0.8-0.9
Pavlov. Cond. magazine entry latency0.00.00.50.00.0-0.1-0.0-0.70.40.1-0.1-0.10.10.1-0.0-0.00.1-0.5-0.0-0.10.0-0.1-0.00.0-0.20.10.1
Pavlov. Cond. change in total contacts0.10.10.30.30.20.2-0.3-0.60.60.4-0.30.10.20.20.20.20.1-0.20.30.20.2-0.1-0.30.30.2-0.10.0
Pavlov. Cond. index score0.10.10.90.30.20.2-0.3-0.90.60.4-0.30.10.40.30.20.30.3-0.40.20.20.30.2-0.40.40.00.30.3
Pavlov. Cond. latency score0.10.10.70.30.20.2-0.3-0.80.50.4-0.30.10.30.20.20.20.4-0.40.20.20.30.2-0.30.30.00.40.4
Pavlov. Cond. lever contacts0.50.51.70.80.60.6-0.8-1.30.80.9-0.80.60.80.70.60.70.80.00.60.60.80.7-0.80.90.20.70.8
Pavlov. Cond. magazine entry number0.20.31.2-0.6-0.5-0.40.61.1-0.9-0.70.6-0.4-0.6-0.4-0.3-0.4-0.50.2-0.2-0.3-0.4-0.30.4-0.4-0.0-0.5-0.4
Pavlov. Cond. intertrial magazine entries0.81.01.60.70.70.8-0.7-1.20.40.8-0.90.80.91.11.11.11.01.21.31.21.21.3-1.21.21.10.70.9
Pavlov. Cond. lever-magazine prob. diff.0.30.41.70.60.60.5-0.6-1.30.90.7-0.70.50.70.60.60.60.6-0.00.60.60.70.6-0.70.70.30.60.6
Pavlov. Cond. response bias0.81.02.31.10.90.9-1.1-1.51.31.2-1.10.91.11.00.91.01.00.30.80.91.00.9-1.11.10.40.91.0
Pavlov. Cond. lever latency0.50.71.0-1.0-1.0-1.00.80.9-0.9-0.90.8-0.9-0.7-0.8-0.9-0.8-0.6-1.0-0.9-0.9-0.8-1.00.8-0.8-1.0-0.4-0.4
Pavlov. Cond. magazine entry latency0.10.11.2-0.1-0.0-0.10.2-1.1-0.10.00.2-0.1-0.2-0.1-0.1-0.1-0.20.2-0.1-0.1-0.1-0.20.1-0.1-0.0-0.3-0.3
Pavlov. Cond. change in total contacts0.00.10.60.20.30.2-0.1-0.80.40.3-0.20.10.10.20.20.10.20.30.20.10.20.1-0.20.20.20.10.1
Pavlov. Cond. index score0.30.51.80.60.70.6-0.5-1.40.70.7-0.60.60.50.60.60.60.60.90.70.60.60.6-0.60.60.70.50.5
Pavlov. Cond. latency score0.40.52.40.70.80.7-0.5-1.60.70.7-0.60.70.60.60.70.60.50.90.70.70.60.6-0.60.60.80.40.4
Pavlov. Cond. lever contacts0.20.30.50.60.70.6-0.5-0.60.60.5-0.50.60.50.50.60.60.30.60.60.60.60.7-0.60.60.60.20.2
Pavlov. Cond. magazine entry number0.20.20.40.60.40.5-0.60.50.50.4-0.50.50.50.50.40.50.40.20.40.40.40.5-0.40.40.40.40.4
Pavlov. Cond. intertrial magazine entries1.42.16.4-1.4-1.4-1.41.42.5-1.7-1.61.4-1.3-1.3-1.4-1.5-1.5-1.1-1.4-1.1-1.5-1.6-1.31.7-1.7-0.7-0.9-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.21.30.30.50.4-0.2-1.10.40.4-0.30.30.30.30.30.30.30.70.40.30.30.3-0.30.30.50.30.3
Pavlov. Cond. response bias0.40.60.90.90.90.9-0.7-1.00.90.8-0.70.80.70.80.80.80.70.90.70.80.80.9-0.80.80.70.50.4
Time in closed arm before self-admin0.10.10.3-0.3-0.4-0.30.40.3-0.2-0.30.1-0.5-0.1-0.3-0.4-0.3-0.0-0.3-0.5-0.4-0.3-0.00.3-0.3-0.60.00.3
Time in closed arm after self-admin0.90.91.6-1.2-1.3-1.21.20.3-0.8-1.00.8-1.2-0.8-1.0-1.0-1.0-0.7-1.0-1.0-1.0-0.9-0.80.9-0.9-1.3-0.5-0.2
Time in open arm before self-admin0.00.10.5-0.00.1-0.0-0.10.40.1-0.0-0.10.1-0.1-0.00.0-0.0-0.2-0.30.20.1-0.0-0.70.0-0.00.4-0.2-0.5
Time in open arm after self-admin0.10.10.30.50.50.4-0.60.60.20.4-0.40.40.40.30.30.30.2-0.00.30.30.30.2-0.30.30.30.10.0
Bone: periosteal estimation0.20.40.90.80.80.7-0.8-0.80.70.8-0.70.70.70.60.60.60.70.30.50.50.60.6-0.60.60.31.00.7
Bone: periosteal perimeter0.00.00.30.10.10.1-0.1-0.60.10.2-0.10.10.20.10.00.10.3-0.10.00.00.10.1-0.10.1-0.30.40.3
Bone: post-yield work1.52.22.71.41.41.4-1.4-1.31.51.5-1.51.31.61.41.51.51.51.21.61.51.51.5-1.51.61.31.71.6
Progressive ratio test 1 active lever presses1.82.33.61.51.51.5-1.7-0.71.81.7-1.91.41.71.51.51.61.61.11.41.51.70.9-1.81.80.81.61.4
Progressive ratio test 1 breakpoint1.92.33.61.51.51.5-1.7-0.71.81.7-1.91.41.71.51.51.61.61.21.41.51.70.9-1.81.80.81.61.5
Progressive ratio test 1 inactive lever presses2.63.85.81.81.81.8-1.9-1.92.12.0-2.01.81.92.02.02.12.01.71.82.02.31.9-2.42.40.91.91.9
Progressive ratio test 2 active lever presses3.84.45.42.12.12.1-2.2-1.42.32.1-2.32.22.32.22.12.12.21.92.22.12.11.8-2.02.02.12.12.2
Progressive ratio test 2 breakpoint3.74.25.12.12.12.1-2.1-1.32.32.0-2.22.22.22.12.12.12.11.92.22.12.01.7-2.02.02.12.02.0
Progressive ratio test 2 inactive lever presses3.55.76.62.42.42.4-2.5-1.52.62.4-2.62.52.52.52.42.42.62.52.52.42.31.9-2.32.32.42.52.5
Incentive Sensitization - Responses2.53.55.31.81.81.8-1.7-1.31.91.7-1.92.02.01.92.01.91.91.82.22.01.81.8-1.81.72.31.72.0
Incentive Sensitization - Breakpoint2.22.94.81.61.71.7-1.5-1.11.71.5-1.71.81.81.81.81.71.71.72.01.91.71.7-1.61.62.21.51.8
Sum of active levers in priming session hrs 5-60.10.10.40.1-0.0-0.1-0.0-0.4-0.3-0.10.2-0.1-0.2-0.3-0.3-0.2-0.5-0.4-0.4-0.3-0.3-0.10.3-0.3-0.3-0.6-0.4
Progressive ratio0.10.22.3-0.2-0.2-0.20.41.5-0.4-0.40.3-0.3-0.1-0.3-0.3-0.30.1-0.4-0.1-0.3-0.20.40.2-0.2-0.20.30.3
Food seeking constrained by brief footshock10.412.717.63.43.33.3-3.2-3.23.43.4-3.53.33.63.73.73.73.72.83.83.74.04.2-4.04.03.03.63.7
Seeking ratio, punishment vs. effort1.62.35.61.51.51.5-1.6-2.41.71.6-1.51.61.31.61.61.61.21.51.51.61.61.2-1.61.51.51.01.0
Retroperitoneal fat weight43.3184.7206.9-14.4-14.3-14.314.213.1-14.0-14.013.9-14.1-13.8-13.8-13.7-13.7-13.2-13.4-13.3-13.5-13.4-13.813.3-13.3-12.8-12.4-12.3
Reaction time number correct0.30.71.20.80.80.8-0.7-1.10.80.9-0.80.80.90.80.70.71.10.50.70.70.70.9-0.70.60.70.91.1
Reaction time mean minus median0.61.42.7-1.6-1.5-1.61.61.1-1.6-1.61.1-1.4-1.0-1.0-1.0-1.0-0.9-1.4-0.9-0.9-0.8-0.80.8-0.8-1.5-1.0-0.7
Reaction time mean minus median AUC0.51.32.3-1.3-1.2-1.31.41.4-1.4-1.41.0-1.2-1.0-1.1-1.1-1.0-0.9-1.4-1.1-1.0-0.9-0.80.9-0.9-1.5-1.1-0.8
Reaction time num false alarms2.12.94.2-1.7-1.8-1.61.82.0-1.7-1.71.6-1.7-1.6-1.7-1.7-1.7-1.7-2.0-1.8-1.7-1.6-1.31.6-1.6-1.9-1.7-1.7
Reaction time num false alarms AUC1.82.85.2-1.5-1.7-1.51.72.3-1.6-1.71.5-1.6-1.5-1.7-1.7-1.6-1.6-2.0-1.9-1.8-1.6-1.21.6-1.6-1.9-1.7-1.6
Reaction time trials correct on left0.30.71.20.80.80.8-0.7-1.10.80.9-0.80.80.90.80.70.71.10.50.70.70.70.9-0.70.60.70.91.1
Reaction time trials on left0.30.61.10.70.80.8-0.6-1.00.70.8-0.80.70.80.70.60.71.00.40.70.60.70.9-0.60.60.60.81.0
Reaction time mean0.40.61.7-0.8-0.7-0.80.91.3-1.1-1.10.8-0.7-0.8-0.7-0.6-0.6-0.8-0.6-0.6-0.5-0.6-0.40.6-0.6-0.5-1.1-1.0
Reaction time mean AUC0.20.41.6-0.6-0.5-0.50.61.3-0.9-0.90.6-0.5-0.6-0.5-0.5-0.4-0.6-0.5-0.5-0.4-0.4-0.20.4-0.4-0.4-0.8-0.7
Median of all reaction times0.10.11.0-0.2-0.1-0.20.31.0-0.6-0.50.4-0.1-0.4-0.3-0.2-0.2-0.50.0-0.2-0.2-0.2-0.10.3-0.30.1-0.6-0.6
Reaction time omissions0.91.34.5-1.0-1.2-1.21.10.9-0.9-1.00.8-1.2-0.8-1.1-1.2-1.0-1.0-2.0-1.3-1.2-0.9-0.60.8-0.7-2.1-1.2-0.8
Reaction time false alarm rate2.83.86.4-1.8-2.0-1.82.02.5-1.9-2.01.8-1.9-1.9-2.0-2.0-1.9-2.0-2.0-2.1-2.0-1.9-1.71.8-1.8-2.0-1.9-2.0
Reaction time premature initiation rate0.00.10.80.10.10.1-0.20.90.10.00.10.00.00.0-0.0-0.1-0.00.10.1-0.1-0.10.20.2-0.20.6-0.00.1
Reaction time premature initiations0.20.31.00.60.60.6-0.60.30.50.5-0.40.50.50.50.40.40.60.50.50.40.30.8-0.20.21.00.40.6
Std. dev. reaction times1.01.82.9-1.5-1.4-1.51.61.7-1.5-1.71.2-1.4-1.2-1.2-1.2-1.2-1.2-1.4-1.2-1.1-1.0-0.91.0-1.0-1.5-1.4-1.2
Reaction time trials completed0.30.61.10.70.80.8-0.6-1.00.70.8-0.80.70.80.70.60.71.00.40.70.60.70.9-0.60.60.60.81.0
Reaction time trials AUC0.30.51.00.60.70.7-0.6-0.90.70.7-0.70.60.80.70.60.71.00.30.70.60.70.9-0.60.60.60.81.0
Run reversals in cocaine runway, females0.80.81.50.91.01.0-0.8-1.21.10.8-0.71.00.71.01.00.90.71.20.91.00.91.0-0.90.81.00.60.4
Run reversals in cocaine runway, males1.11.12.01.00.91.0-1.00.21.00.9-0.91.11.11.01.01.11.31.11.01.01.01.1-1.01.00.61.41.4
Latency to leave start box in cocaine runway0.20.20.50.30.30.4-0.4-0.20.30.4-0.50.40.50.40.50.50.30.40.70.60.5-0.0-0.50.50.70.40.5
Latency to leave start box in cocaine runway, F0.10.20.6-0.6-0.5-0.50.50.5-0.5-0.50.3-0.5-0.3-0.4-0.3-0.3-0.5-0.3-0.1-0.2-0.2-0.80.2-0.2-0.2-0.4-0.2
Latency to leave start box in cocaine runway, M1.00.91.31.01.01.0-1.0-0.90.90.9-1.01.01.00.91.01.00.91.01.01.00.90.8-0.90.91.10.91.0
Std. dev. time between licks in bursts0.30.51.1-0.3-0.5-0.40.30.8-0.4-0.50.5-0.6-0.6-0.7-0.7-0.7-0.8-0.8-0.8-0.8-0.8-0.70.8-0.8-0.5-0.9-1.1
Total sessions with >9 infusions2.73.34.31.91.91.9-1.7-1.22.01.9-2.01.81.91.91.81.82.11.81.81.71.81.6-1.81.81.62.01.8
Short access day 1 total inactive lever presses4.96.57.82.82.72.7-2.6-2.32.32.5-2.62.82.62.62.62.62.52.52.52.62.62.5-2.62.62.32.32.4
Short access day 10 total inactive lever presses0.20.51.70.60.50.6-0.7-1.30.40.6-0.50.80.70.70.70.80.60.40.60.80.90.9-0.91.00.10.70.7
Short access day 1 total infusions2.73.54.51.71.71.8-1.6-1.72.02.0-1.91.81.82.01.91.92.12.11.92.02.01.8-2.02.01.52.11.9
Short access day 10 total infusions2.53.24.41.71.61.7-1.5-1.21.81.6-1.71.81.81.91.92.01.81.72.02.02.01.8-2.12.11.51.71.7
Short access total infusions1.82.22.91.41.41.4-1.3-1.21.71.6-1.61.41.51.61.51.61.71.51.51.51.61.2-1.71.71.11.61.5
Short access day 1 locomotion1.92.44.01.31.31.3-1.2-1.71.61.7-1.61.31.71.61.41.52.01.01.41.41.61.6-1.61.60.92.01.9
Short access day 10 total locomotion1.32.42.91.71.61.7-1.6-1.01.41.5-1.71.51.61.61.61.61.71.21.51.51.61.5-1.61.61.31.61.6
Short access total locomotion2.12.53.31.81.71.7-1.7-1.11.71.8-1.81.51.71.61.51.51.71.21.51.41.51.2-1.51.51.51.71.6
One hour access (0.3 mA shock)4.65.38.52.22.32.3-2.3-1.22.32.2-2.42.42.42.32.32.22.62.62.62.32.01.7-1.91.92.92.62.5
Compulsive drug intake1.21.44.2-0.8-0.8-0.80.82.0-1.5-1.21.3-0.7-1.3-1.2-1.1-1.2-1.2-0.5-1.0-1.1-1.4-1.21.6-1.60.1-1.1-1.3
One hour access (shock baseline)4.97.59.92.52.52.5-2.6-3.12.92.8-3.02.52.92.82.82.82.92.72.92.82.82.2-2.72.72.62.72.9
Social response proportion0.10.10.5-0.7-0.6-0.70.5-0.5-0.4-0.30.3-0.5-0.2-0.2-0.1-0.20.10.10.40.0-0.2-0.50.2-0.20.40.10.3
Social responses0.30.41.0-0.9-0.9-0.90.70.0-0.6-0.50.6-0.8-0.5-0.7-0.7-0.7-0.5-0.4-0.5-0.6-0.7-1.00.6-0.6-0.8-0.4-0.3
Social time0.10.10.9-0.4-0.3-0.30.3-1.0-0.1-0.30.2-0.3-0.1-0.1-0.1-0.1-0.10.20.1-0.0-0.00.00.0-0.00.1-0.30.1
Soleus weight3.911.416.03.63.63.6-3.6-4.03.43.4-3.53.53.43.43.33.33.22.93.13.23.23.5-3.23.23.13.03.2
Bone: stiffness0.00.10.3-0.0-0.1-0.10.00.50.0-0.00.1-0.2-0.2-0.2-0.2-0.2-0.4-0.5-0.3-0.2-0.2-0.30.1-0.1-0.3-0.3-0.6
Tibialis anterior weight1.44.78.62.32.32.3-2.3-2.92.12.4-2.32.22.32.12.12.12.22.01.82.02.02.0-2.02.01.72.22.2
Time to tail flick, vehicle, before self-admin0.10.11.5-0.2-0.3-0.30.1-0.20.20.1-0.1-0.20.1-0.1-0.2-0.10.3-0.9-0.5-0.20.00.0-0.10.1-1.20.5-0.0
Time to tail flick, vehicle, after self-admin5.77.610.7-3.2-3.0-3.22.92.4-2.5-2.82.6-2.9-2.6-2.8-2.8-2.8-2.5-2.8-2.8-2.8-2.7-3.32.7-2.6-2.9-2.1-2.1
Time to tail flick, test, before self-admin0.30.31.10.30.40.3-0.6-0.80.60.6-0.80.40.90.60.50.50.70.10.60.50.50.5-0.50.50.40.71.0
Time to tail flick, test, after self-admin1.31.32.10.91.10.9-1.2-1.41.01.2-1.31.11.31.21.21.21.10.71.21.21.20.8-1.31.31.01.11.1
Delta time to tail flick, vehicle, before/after SA2.32.23.7-1.6-1.5-1.51.41.6-1.4-1.51.5-1.4-1.5-1.5-1.5-1.5-1.6-1.1-1.3-1.4-1.5-1.91.5-1.5-0.9-1.6-1.3
Delta time to tail flick, test, before/after SA2.02.13.21.41.51.4-1.4-0.91.11.3-1.21.51.31.51.61.61.41.71.71.71.51.4-1.61.61.81.31.1
Tibia length0.51.52.2-1.3-1.4-1.31.30.1-1.1-1.11.2-1.4-1.1-1.3-1.4-1.4-0.8-1.3-1.2-1.4-1.4-1.51.4-1.4-1.1-0.4-0.4
Ambulatory time before self-admin0.00.10.30.30.40.3-0.2-0.10.20.1-0.40.30.40.20.20.2-0.00.10.00.20.30.6-0.30.3-0.4-0.10.2
Ambulatory time after self-admin0.10.10.30.0-0.0-0.00.20.1-0.3-0.20.3-0.1-0.4-0.3-0.2-0.3-0.30.0-0.4-0.3-0.4-0.50.4-0.4-0.2-0.3-0.6
Bone: tissue strength0.40.40.7-0.7-0.7-0.60.60.5-0.6-0.60.8-0.6-0.8-0.7-0.7-0.7-0.5-0.4-0.6-0.7-0.7-0.80.7-0.7-0.4-0.2-0.5
Total heroin consumption4.35.06.82.32.62.3-2.5-2.42.52.4-2.22.42.12.32.32.22.22.42.22.22.01.7-1.91.92.62.11.9
Bone: trabecular number2.94.910.92.02.02.0-2.1-3.32.32.3-2.22.12.32.22.12.12.41.92.12.12.11.8-2.12.11.72.62.5
Bone: trabecular spacing0.50.72.0-0.4-0.5-0.50.51.4-0.7-0.50.6-0.6-0.8-0.8-0.8-0.8-1.1-0.5-1.0-0.9-0.8-0.80.8-0.8-0.8-1.3-1.2
Bone: trabecular thickness0.10.10.5-0.0-0.0-0.0-0.0-0.3-0.1-0.1-0.20.10.40.30.30.30.60.10.50.40.40.6-0.40.40.20.70.7
Bone: trabecular tissue density0.10.10.50.30.30.3-0.10.70.0-0.1-0.20.30.20.30.30.30.00.30.30.30.30.7-0.30.30.2-0.10.1
Water consumed over 24 hours0.10.10.4-0.0-0.1-0.1-0.0-0.2-0.1-0.00.0-0.2-0.1-0.3-0.3-0.3-0.5-0.5-0.5-0.4-0.40.00.3-0.3-0.4-0.6-0.4
Number of responses in last shaping day1.21.31.91.01.01.1-1.0-1.41.11.1-1.21.01.11.21.21.21.11.01.21.21.20.9-1.31.31.11.01.0