Ech1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_039089636.1 0.02 0.02 3.5e-03 0.01 0.01 0.01 0 2.7e-02 4.6e-02 6.6e-02 9.1e-02
2 Adipose alternative TSS XM_039089636.1 0.02 0.02 5.7e-03 0.01 0.01 0 0.01 3.1e-02 5.4e-02 1.2e-01 5.8e-02
3 pVTA gene expression Ech1 0.08 0.06 1.9e-03 0.05 0.03 0.04 0.03 3.0e-03 3.0e-02 5.7e-03 1.5e-02
4 LHb alternative TSS NM_022594.1 0.19 0.13 3.4e-03 0.09 0.04 0.05 0.09 3.5e-03 4.1e-02 2.9e-02 4.7e-03
5 LHb alternative TSS XM_039089636.1 0.16 0.12 7.0e-03 0.08 0.03 0.03 0.07 6.8e-03 7.4e-02 7.6e-02 1.1e-02
6 LHb mRNA stability Ech1 0.18 0.12 9.7e-04 0.14 0.12 0.12 0.12 3.7e-04 1.1e-03 9.9e-04 8.8e-04
7 Liver mRNA stability Ech1 0.56 0.16 0.0e+00 0.38 0.38 0.37 0.38 2.0e-44 2.3e-44 1.8e-43 3.5e-45
8 Adipose isoform ratio NM_022594.1 0.03 0.02 1.3e-03 0.01 0.01 0.01 0.01 1.5e-02 9.5e-03 3.3e-02 2.0e-02
9 Adipose alternative TSS NM_022594.1 0.03 0.02 1.4e-03 0 0 0 0 9.5e-02 9.0e-02 1.2e-01 1.2e-01
10 PL mRNA stability Ech1 0.22 0.22 5.9e-15 0.13 0.12 0.14 0.13 1.8e-14 3.8e-13 5.9e-15 1.9e-14
11 Brain mRNA stability Ech1 0.14 0.09 9.3e-13 0.16 0.13 0.14 0.15 2.8e-14 4.9e-12 1.6e-12 1.7e-13
12 LHb isoform ratio XM_039089636.1 0.18 0.12 6.7e-03 0.08 0.05 0.04 0.08 5.7e-03 2.3e-02 3.6e-02 7.2e-03
13 NAcc mRNA stability Ech1 0.16 0.1 0.0e+00 0.17 0.15 0.17 0.01 1.1e-19 1.2e-16 7.2e-19 6.8e-03
14 Brain gene expression Ech1 0.09 0.06 2.3e-08 0.08 0.06 0.07 0.08 9.8e-08 1.9e-06 2.8e-07 8.5e-08
15 Adipose gene expression Ech1 0.06 0.04 7.0e-05 0.01 0.02 0.01 0.01 1.4e-02 5.8e-03 1.2e-02 9.9e-03
16 BLA mRNA stability Ech1 0.23 0.13 1.0e-10 0.16 0.18 0.16 0.16 3.6e-09 5.3e-10 6.7e-09 4.4e-09
17 pVTA mRNA stability Ech1 0.35 0.15 2.6e-15 0.35 0.23 0.34 0.24 8.1e-16 1.4e-10 1.3e-15 1.0e-10
18 Adipose mRNA stability Ech1 0.13 0.08 3.3e-11 0.06 0.07 0.06 0.07 1.1e-07 3.8e-08 1.1e-07 2.7e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.10.10.4-0.3-0.3-0.20.2-0.20.2-0.20.10.1-0.10.3-0.30.20.4-0.5-0.60.7-0.7
Area under the delay curve0.00.00.10.20.20.2-0.30.3-0.30.2-0.3-0.3-0.20.2-0.2-0.20.00.10.1-0.1-0.0
BMI with tail0.10.30.7-0.7-0.7-0.70.4-0.40.4-0.5-0.8-0.80.70.4-0.40.60.5-0.4-0.40.5-0.5
BMI without tail0.20.40.60.60.60.7-0.80.8-0.80.80.30.2-0.6-0.70.7-0.7-0.70.70.7-0.70.6
Body weight2.811.613.63.43.43.6-3.73.7-3.73.73.73.7-3.7-3.13.0-3.6-3.23.23.1-2.92.9
Weight adjusted by age0.10.20.2-0.4-0.4-0.30.5-0.50.5-0.4-0.5-0.50.40.3-0.30.40.4-0.3-0.30.2-0.3
Bone surface0.30.51.40.70.70.8-0.60.6-0.60.71.11.2-0.8-0.60.6-0.8-0.50.30.3-0.30.3
Bone volume0.30.51.30.70.70.7-0.70.7-0.70.71.11.1-0.9-0.70.7-0.8-0.50.30.3-0.30.3
Breakpoint value in progressive ratio session1.21.42.71.31.31.1-1.11.1-1.11.00.20.1-1.5-1.21.2-0.9-1.01.61.7-1.21.2
Number of licking bursts2.22.63.4-1.8-1.8-1.71.8-1.81.8-1.7-0.9-0.81.81.3-1.31.71.6-1.8-1.81.4-1.4
Context. condit. distance diff. score0.10.10.1-0.3-0.3-0.30.3-0.30.3-0.3-0.3-0.30.10.3-0.30.30.3-0.2-0.20.2-0.2
Locomotion velocity, session 12.62.83.6-1.5-1.5-1.71.7-1.71.7-1.8-1.9-1.91.81.6-1.71.71.7-1.5-1.51.7-1.7
Locomotion distance, session 10.81.11.31.21.21.1-1.01.0-1.01.01.01.0-1.0-1.01.0-1.0-1.01.01.0-0.91.0
Locomotion velocity, session 20.30.40.6-0.7-0.7-0.60.4-0.40.4-0.5-0.7-0.70.50.7-0.70.60.6-0.6-0.60.7-0.7
Locomotion distance, session 20.50.61.5-0.9-0.9-0.80.6-0.60.6-0.7-1.2-1.20.60.7-0.70.80.7-0.5-0.50.8-0.8
Locomotion velocity, session 30.30.30.9-0.7-0.7-0.60.5-0.50.5-0.50.50.61.00.2-0.30.60.4-0.7-0.80.3-0.3
Locomotion distance, session 36.16.68.12.52.52.5-2.62.6-2.62.72.92.8-2.3-2.62.6-2.6-2.62.42.4-2.62.6
Stereotopy head waving bouts, day 30.70.81.6-1.3-1.3-1.11.0-1.01.0-1.0-0.9-1.00.90.5-0.51.00.7-0.5-0.40.6-0.6
Stereotopy head waving duration, day 32.93.54.4-2.1-2.1-2.02.0-2.02.0-2.0-1.9-1.91.91.7-1.61.91.8-1.6-1.61.7-1.7
Locomotion velocity, session 70.00.00.30.10.10.0-0.10.1-0.10.10.50.50.00.0-0.1-0.10.1-0.2-0.20.2-0.1
Locomotion distance, session 70.10.20.50.30.30.3-0.40.4-0.40.40.70.7-0.4-0.40.3-0.3-0.30.10.1-0.20.2
Stereotopy head waving bouts, day 70.10.10.2-0.5-0.5-0.30.3-0.30.3-0.2-0.3-0.40.10.1-0.10.20.2-0.0-0.00.2-0.2
Stereotopy head waving duration, day 71.01.22.0-1.3-1.3-1.21.1-1.11.1-1.1-1.4-1.41.01.0-1.01.11.1-0.8-0.81.0-1.0
Locomotion velocity, session 83.23.85.1-2.3-2.3-2.21.9-1.91.9-2.0-1.6-1.52.01.8-1.82.11.9-2.0-2.02.0-1.9
Locomotion distance, session 80.40.51.4-0.8-0.8-0.80.6-0.60.6-0.7-1.1-1.20.50.6-0.70.70.7-0.4-0.40.7-0.7
Degree of sensitization distance3.43.44.1-1.7-1.7-1.81.8-1.81.8-1.9-1.8-1.81.61.9-1.91.91.9-1.9-1.92.0-2.0
Degree of sensitization stereotypy0.00.00.2-0.2-0.2-0.10.1-0.10.1-0.1-0.4-0.4-0.1-0.00.00.00.00.20.2-0.00.0
Conditioned locomotion0.40.51.80.20.20.4-0.40.4-0.40.61.31.3-0.4-0.90.9-0.5-0.70.50.5-0.80.8
Cocaine response after cond. corrected0.40.51.00.50.50.6-0.70.7-0.70.71.01.0-0.5-0.70.8-0.7-0.80.60.5-0.80.8
Cocaine response after cond. not corrected0.80.91.50.50.50.7-1.01.0-1.01.01.21.2-0.7-1.01.1-0.8-1.00.80.8-1.01.0
Cocaine response before conditioning1.62.02.81.01.01.2-1.51.5-1.51.41.21.2-1.4-1.71.7-1.3-1.51.51.5-1.51.5
Saline control response0.40.61.20.70.70.7-0.70.7-0.70.7-0.0-0.1-0.8-1.01.0-0.8-0.81.01.1-0.80.8
Bone: connectivity density0.50.81.4-0.8-0.8-0.80.8-0.80.8-0.8-0.6-0.50.51.0-1.00.81.0-1.1-1.11.2-1.2
Bone: cortical apparent density2.22.94.6-1.7-1.7-1.81.7-1.71.7-1.7-2.1-2.11.41.7-1.71.81.6-1.4-1.41.7-1.7
Bone: cortical area2.03.13.71.71.71.8-1.71.7-1.71.81.61.5-1.9-1.91.9-1.8-1.71.91.9-1.61.6
Bone: cortical porosity0.70.71.5-1.2-1.2-1.00.7-0.70.7-0.8-0.8-0.81.00.9-0.90.90.7-0.7-0.70.7-0.7
Bone: cortical porosity0.80.81.8-1.3-1.3-1.10.8-0.80.8-0.8-0.8-0.81.10.9-0.91.00.8-0.8-0.80.7-0.7
Bone: cortical thickness0.91.42.11.11.11.1-1.11.1-1.11.11.11.0-1.4-1.41.4-1.1-1.11.31.3-1.11.1
Bone: cortical thickness0.10.10.4-0.6-0.6-0.40.1-0.10.1-0.20.00.1-0.00.2-0.20.40.2-0.3-0.30.3-0.2
Bone: cortical tissue density2.63.45.1-1.9-1.9-1.91.8-1.81.8-1.9-2.2-2.31.51.8-1.81.91.8-1.6-1.51.9-1.9
Condit. Reinf. active minus inactive responses0.30.30.5-0.6-0.6-0.70.6-0.60.6-0.7-0.3-0.30.50.4-0.40.70.5-0.6-0.60.5-0.5
Condit. Reinf. active-inactive response ratio0.30.30.6-0.6-0.6-0.60.8-0.80.8-0.7-0.4-0.40.50.3-0.30.60.5-0.4-0.40.4-0.4
Condit. Reinf. active responses0.91.11.4-1.2-1.2-1.21.0-1.01.0-1.0-0.8-0.80.91.1-1.11.21.1-1.2-1.21.1-1.2
Condit. Reinf. inactive responses0.50.61.0-0.8-0.8-0.80.5-0.50.5-0.6-0.7-0.70.61.0-1.00.70.8-0.9-0.91.0-1.0
Incentive salience index mean0.00.00.2-0.2-0.2-0.20.0-0.00.0-0.00.40.40.10.1-0.10.20.1-0.3-0.30.1-0.1
Condit. Reinf. lever presses0.20.30.60.50.50.5-0.70.7-0.70.60.70.8-0.5-0.30.3-0.5-0.50.20.2-0.40.4
Condit. Reinf. active minus inactive responses4.25.26.62.32.32.2-2.22.2-2.22.22.02.0-2.1-2.62.5-2.2-2.42.42.4-2.52.5
Condit. Reinf. active-inactive response ratio2.72.84.41.41.41.5-1.61.6-1.61.61.21.1-1.6-2.02.0-1.6-1.82.02.1-2.02.0
Condit. Reinf. active responses4.96.88.22.62.62.5-2.62.6-2.62.62.32.3-2.3-2.92.8-2.5-2.72.62.6-2.82.8
Condit. Reinf. inactive responses1.61.92.81.71.71.5-1.51.5-1.51.41.11.1-1.3-1.41.3-1.4-1.41.31.3-1.31.2
Condit. Reinf. lever presses7.39.911.53.43.43.1-3.33.3-3.33.23.13.1-2.8-3.33.3-3.0-3.22.92.8-3.13.1
Condit. Reinf. lever reinforcers received5.88.29.92.92.92.8-2.82.8-2.82.82.82.7-2.5-3.13.1-2.8-3.02.82.8-3.03.0
Conditioned reinforcement - actives0.50.51.00.50.50.8-0.50.5-0.50.60.90.9-0.3-1.01.0-0.5-0.80.40.4-0.70.6
Conditioned reinforcement - inactives2.12.34.01.51.51.5-1.51.5-1.51.52.02.0-1.6-1.31.3-1.3-1.51.31.3-1.51.5
Conditioned locomotion0.91.11.9-1.4-1.4-1.11.1-1.11.1-1.1-0.7-0.61.40.7-0.71.00.9-1.2-1.20.8-0.8
Patch foraging indifference point 0 sec0.40.61.10.70.70.6-0.90.9-0.90.80.70.7-0.6-0.91.0-0.6-0.90.60.6-0.70.7
Patch foraging indifference point AUC0.50.61.5-0.6-0.6-0.50.7-0.70.7-0.7-1.2-1.20.30.9-0.90.50.9-0.4-0.31.1-1.1
Delay disc. indifference point, 0s delay0.70.71.40.90.90.9-1.21.2-1.21.0-0.1-0.2-0.8-0.60.6-0.9-0.90.80.9-0.70.6
Delay disc. indifference point, 16s delay1.41.42.01.31.31.3-1.41.4-1.41.41.11.1-1.1-1.01.0-1.3-1.10.90.9-1.11.0
Delay disc. indifference point, 2s delay0.00.00.1-0.1-0.1-0.10.1-0.10.1-0.1-0.4-0.40.10.3-0.30.10.2-0.2-0.20.1-0.2
Delay disc. indifference point, 24s delay1.31.22.21.21.21.2-1.31.3-1.31.31.31.3-1.5-0.60.6-1.2-0.80.90.8-0.80.8
Delay disc. indifference point, 4s delay0.10.10.20.30.30.3-0.40.4-0.40.40.00.0-0.2-0.20.2-0.3-0.20.20.2-0.30.1
Delay disc. indifference point, 8s delay1.01.12.2-1.0-1.0-0.90.9-0.90.9-0.9-1.5-1.50.71.2-1.21.01.2-0.8-0.81.0-1.1
Indifference point function ln k0.50.72.00.80.80.7-0.80.8-0.80.81.41.4-0.4-1.01.0-0.7-0.90.40.4-0.80.9
Indifference point function log k0.50.72.00.80.80.7-0.80.8-0.80.81.41.4-0.4-1.01.0-0.7-0.90.40.4-0.80.9
Patch foraging total patch changes 0 sec0.50.71.20.80.80.8-1.01.0-1.00.90.80.9-0.7-1.01.1-0.7-1.00.70.7-0.80.8
Patch foraging total patch changes 12 sec0.40.50.90.70.70.7-0.90.9-0.90.80.30.3-0.9-0.70.6-0.7-0.70.70.7-0.40.4
Patch foraging total patch changes 18 sec0.20.31.6-0.2-0.2-0.20.2-0.20.2-0.3-1.2-1.3-0.20.5-0.40.20.40.10.10.6-0.5
Patch foraging total patch changes 24 sec0.70.91.31.21.21.1-1.11.1-1.11.00.60.6-1.0-0.80.8-1.0-0.90.90.9-0.60.6
Patch foraging total patch changes 6 sec0.10.20.40.40.40.4-0.60.6-0.60.5-0.1-0.1-0.6-0.30.3-0.4-0.40.50.5-0.20.2
Patch foraging time to switch 0 sec1.11.72.7-1.3-1.3-1.31.1-1.11.1-1.2-1.4-1.41.01.5-1.61.31.4-1.3-1.31.4-1.3
Patch foraging water rate 0 sec0.50.81.4-0.9-0.9-0.91.0-1.01.0-0.80.00.11.20.7-0.60.90.8-1.0-1.10.8-0.7
Patch foraging water rate 12 sec0.81.23.41.21.21.0-0.90.9-0.91.01.81.8-1.0-0.60.7-1.0-1.00.80.7-1.01.1
Patch foraging water rate 18 sec0.71.02.0-0.9-0.9-1.11.1-1.11.1-1.0-0.2-0.11.40.9-0.71.10.9-1.2-1.30.9-0.8
Patch foraging water rate 24 sec0.30.51.70.40.40.4-0.30.3-0.30.51.31.3-0.3-0.80.9-0.4-0.60.50.5-0.91.0
Patch foraging water rate 6 sec0.10.21.20.40.40.20.1-0.10.10.21.01.10.1-0.30.4-0.2-0.2-0.0-0.1-0.30.3
Seeking ratio, delayed vs. immediate footshock1.11.31.71.11.10.9-1.21.2-1.21.11.01.0-1.3-1.21.2-0.9-1.11.31.3-1.31.2
Distance traveled before self-admin1.81.92.31.31.31.2-1.41.4-1.41.41.41.4-1.3-1.51.5-1.0-1.41.51.5-1.51.5
Distance traveled after self-admin5.35.87.02.72.72.5-2.32.3-2.32.42.42.3-2.3-2.52.5-2.5-2.42.42.4-2.42.4
Extensor digitorum longus weight0.20.70.9-0.9-0.9-0.90.7-0.70.7-0.8-0.8-0.80.90.7-0.80.90.8-0.9-0.90.8-0.9
Bone: elastic displacement0.00.00.1-0.2-0.2-0.20.1-0.10.1-0.1-0.1-0.10.20.3-0.20.20.2-0.3-0.30.4-0.4
Bone: elastic work2.22.93.81.61.61.6-1.81.8-1.81.81.91.9-1.7-1.71.8-1.6-1.71.61.5-1.51.5
Bone: endosteal estimation1.22.63.21.81.81.8-1.71.7-1.71.71.11.1-1.7-1.51.5-1.7-1.51.71.7-1.41.4
Bone: endosteal perimeter1.12.23.11.81.81.7-1.61.6-1.61.61.31.2-1.5-1.41.4-1.6-1.41.41.4-1.31.3
Epididymis fat weight0.00.00.1-0.0-0.00.0-0.10.1-0.1-0.0-0.2-0.20.10.2-0.2-0.00.1-0.1-0.10.2-0.2
Delta time in closed arm before/after self-admin0.90.81.31.01.01.1-1.11.1-1.11.11.11.2-0.9-0.70.7-0.9-0.80.40.4-0.60.6
Delta time in open arm before/after self-admin0.20.10.3-0.5-0.5-0.60.6-0.60.6-0.4-0.1-0.10.40.0-0.00.60.3-0.1-0.10.0-0.0
Diff in mean of infusions in LGA sessions0.10.10.30.20.20.1-0.10.1-0.10.1-0.4-0.4-0.5-0.10.1-0.1-0.10.50.6-0.30.3
Delay discount exponential model param0.00.00.1-0.2-0.2-0.20.3-0.30.3-0.20.20.20.3-0.10.10.2-0.0-0.1-0.10.1-0.0
Extinction: sum of active levers before priming1.31.31.91.31.31.2-1.21.2-1.21.20.40.3-1.3-1.11.1-1.0-1.11.31.4-1.11.1
Active lever presses in extinction session 60.40.41.01.01.00.9-0.70.7-0.70.60.20.1-0.8-0.50.5-0.7-0.40.60.6-0.30.3
Bone: final force1.72.73.61.61.61.7-1.71.7-1.71.71.71.6-1.9-1.71.7-1.7-1.61.71.7-1.51.5
Bone: final moment2.64.14.91.91.92.0-2.02.0-2.02.12.12.1-2.2-2.22.2-2.0-2.02.02.0-1.91.9
Food consumed during 24 hour testing period0.40.51.30.80.80.6-0.60.6-0.60.61.11.2-0.3-0.70.7-0.6-0.60.40.3-0.70.7
Glucose0.30.41.2-0.5-0.5-0.50.4-0.40.4-0.40.10.20.70.8-0.70.50.7-1.0-1.10.8-0.9
Heart weight0.70.91.30.80.80.9-0.90.9-0.91.01.11.1-0.6-0.91.0-1.0-1.11.01.0-1.01.1
Delay discount hyperbolic model param0.00.00.1-0.1-0.1-0.10.1-0.10.1-0.10.30.30.1-0.20.20.1-0.10.00.00.00.1
Intermittent access intake day 1-15 change1.61.62.51.51.51.4-1.51.5-1.51.40.80.8-1.6-0.80.8-1.5-1.11.21.2-0.80.8
Intermittent access intake escalation1.11.11.61.21.21.1-1.31.3-1.31.20.80.7-1.2-0.80.8-1.2-1.01.01.0-0.90.9
Intermittent access intake escalation 23.33.24.41.81.81.8-2.02.0-2.01.91.00.9-2.1-1.61.6-1.9-1.92.02.1-1.71.7
Intermitt. access day 1 inactive lever presses0.50.61.81.01.00.8-0.80.8-0.80.81.31.3-0.7-0.50.4-0.7-0.60.10.0-0.20.4
Intermitt. access day 15 inactive lever presses0.30.41.60.80.80.7-0.50.5-0.50.51.21.3-0.3-0.30.3-0.6-0.4-0.0-0.1-0.10.3
Intermitt. access escalation Index0.20.10.6-0.2-0.2-0.3-0.00.0-0.00.00.0-0.00.1-0.80.8-0.0-0.30.50.5-0.40.5
Intermittent access day 1 total infusions0.30.41.0-0.8-0.8-0.80.5-0.50.5-0.40.70.81.0-0.60.60.6-0.2-0.2-0.3-0.60.5
Intermittent access day 15 total infusions0.91.01.80.70.70.6-0.90.9-0.90.91.31.3-0.6-1.21.2-0.7-1.20.90.8-1.31.2
Intermittent access terminal intake (last 3 days)1.41.52.11.01.01.0-1.21.2-1.21.21.51.5-1.0-1.41.4-1.1-1.41.21.2-1.51.4
Intermittent access total infusions0.60.71.70.40.40.3-0.50.5-0.50.61.31.3-0.1-1.21.2-0.5-1.00.60.6-1.21.1
Intermittent access day 1 locomotion0.30.30.8-0.5-0.5-0.30.2-0.20.2-0.10.70.70.8-0.90.90.3-0.4-0.2-0.2-0.50.4
Intermittent access day 15 total locomotion0.00.00.1-0.2-0.2-0.2-0.20.2-0.20.10.30.40.3-0.10.10.0-0.2-0.3-0.30.0-0.1
Intermittent access total locomotion0.30.30.9-0.8-0.8-0.60.5-0.50.5-0.5-0.00.00.90.1-0.10.50.3-0.8-0.90.4-0.5
Intermittent access standard deviation4.54.86.62.62.62.4-2.22.2-2.22.21.61.6-2.5-2.02.0-2.1-2.12.42.4-2.22.2
Left kidney weight2.98.010.02.52.52.8-2.92.9-2.93.03.23.2-2.7-3.02.9-2.9-2.92.72.7-2.62.6
Right kidney weight4.111.612.73.43.43.5-3.63.6-3.63.63.53.4-3.3-3.33.2-3.5-3.43.43.3-3.23.2
Cocaine induced anxiety0.00.00.20.30.30.50.0-0.00.0-0.1-0.3-0.3-0.10.2-0.20.00.10.00.1-0.00.1
Post-drug Anxiety0.30.40.9-0.1-0.1-0.10.5-0.50.5-0.6-0.9-0.90.60.7-0.70.40.6-0.6-0.60.6-0.7
Baseline Anxiety0.10.10.4-0.6-0.6-0.60.4-0.40.4-0.3-0.1-0.10.6-0.10.10.40.1-0.3-0.30.3-0.4
Tail length5.115.418.54.34.34.2-4.04.0-4.04.13.93.9-4.2-3.53.5-4.2-3.73.73.7-3.63.6
Length with tail7.527.631.65.65.65.6-5.55.5-5.55.55.65.6-5.6-4.74.7-5.5-5.04.94.8-4.64.7
Length without tail3.47.510.32.82.82.8-2.82.8-2.82.83.23.2-2.9-2.62.6-2.8-2.62.52.4-2.42.4
Times rat made contact with spout0.40.51.0-0.8-0.8-0.70.6-0.60.6-0.6-0.9-1.00.50.7-0.70.60.6-0.4-0.40.6-0.6
Lifetime Intake0.20.20.6-0.2-0.2-0.20.0-0.00.00.10.70.80.5-0.80.70.1-0.50.10.0-0.70.6
Liver weight, left0.00.10.2-0.5-0.5-0.2-0.20.2-0.20.0-0.3-0.30.30.2-0.20.10.1-0.2-0.20.3-0.3
Liver weight, right0.00.00.10.10.10.1-0.30.3-0.30.20.40.4-0.20.1-0.0-0.1-0.10.00.0-0.10.1
Locomotor activity0.40.71.2-0.9-0.9-0.80.6-0.60.6-0.6-1.1-1.10.71.0-1.00.70.9-0.6-0.61.0-0.9
Locomotor testing distance0.91.52.1-1.2-1.2-1.31.2-1.21.2-1.2-1.4-1.41.41.2-1.21.31.2-1.0-1.01.2-1.2
Locomotor testing rearing1.62.45.8-1.6-1.6-1.61.3-1.31.3-1.4-2.3-2.41.51.5-1.61.61.4-0.9-0.91.5-1.5
Locomotion in novel chamber0.40.51.6-0.5-0.5-0.70.5-0.50.5-0.5-1.2-1.30.70.6-0.60.60.6-0.5-0.40.7-0.9
Locomotion in novel chamber post-restriction0.00.00.20.20.2-0.20.4-0.40.4-0.20.10.1-0.10.0-0.00.10.20.00.00.0-0.0
Fecal boli incidents, locomotor time 13.03.35.5-1.9-1.9-1.81.7-1.71.7-1.7-1.3-1.22.31.8-1.81.81.7-2.2-2.21.6-2.0
Change in fecal boli incidents, locomotor task0.20.20.90.30.30.3-0.30.3-0.30.2-0.4-0.6-0.5-0.60.6-0.3-0.40.80.9-0.40.5
Time >=10cm from walls, locomotor time 10.00.00.1-0.2-0.2-0.10.1-0.10.1-0.1-0.1-0.10.10.0-0.00.10.2-0.2-0.20.3-0.2
Bouts of movement, locomotor time 10.10.10.30.40.40.4-0.30.3-0.30.3-0.0-0.1-0.4-0.50.5-0.4-0.40.50.5-0.20.0
Total resting periods, locomotor time 10.10.10.20.20.20.2-0.20.2-0.20.20.00.0-0.1-0.50.5-0.2-0.30.30.3-0.1-0.1
Rest time, locomotor task time 10.10.10.3-0.3-0.3-0.20.2-0.20.2-0.20.00.10.50.1-0.10.20.1-0.4-0.40.0-0.3
Distance moved, locomotor task time 10.20.20.60.40.40.4-0.50.5-0.50.40.20.2-0.8-0.20.2-0.4-0.30.50.5-0.20.6
Vertical activity count, locomotor time 11.21.22.11.01.01.1-1.11.1-1.11.00.80.7-1.5-1.01.0-1.1-1.11.31.3-1.11.3
Time >=10cm from walls, locomotor time 20.00.00.20.10.10.2-0.30.3-0.30.2-0.1-0.1-0.4-0.10.1-0.2-0.10.20.30.1-0.1
Bouts of movement, locomotor time 20.20.20.9-0.3-0.3-0.2-0.00.0-0.0-0.1-0.1-0.00.60.3-0.40.20.2-0.8-0.80.7-0.9
Total resting periods, locomotor time 20.20.20.9-0.4-0.4-0.30.1-0.10.1-0.1-0.2-0.10.60.3-0.30.30.3-0.8-0.80.7-1.0
Rest time, locomotor task time 20.20.20.50.30.30.3-0.00.0-0.00.20.70.7-0.5-0.60.6-0.3-0.30.50.5-0.50.5
Distance moved, locomotor task time 20.10.10.40.00.00.0-0.20.2-0.20.1-0.6-0.7-0.10.2-0.2-0.00.00.00.10.2-0.1
Vertical activity count, locomotor time 20.20.20.50.40.40.5-0.70.7-0.70.5-0.3-0.4-0.6-0.20.3-0.5-0.50.60.6-0.20.2
Light reinforcement 10.10.30.7-0.2-0.2-0.30.1-0.10.1-0.3-0.6-0.60.40.8-0.80.40.5-0.5-0.50.8-0.8
Light reinforcement 26.68.910.9-2.9-2.9-3.13.1-3.13.1-3.1-2.4-2.33.22.8-2.73.13.1-3.3-3.33.0-2.9
Bone: marrow area1.22.63.31.81.81.8-1.81.8-1.81.71.21.1-1.7-1.61.5-1.8-1.61.71.7-1.41.4
Bone: maximum diameter1.52.83.31.61.61.7-1.81.8-1.81.81.81.8-1.7-1.81.8-1.7-1.61.51.5-1.41.4
Bone: maximum force2.84.96.32.22.22.2-2.22.2-2.22.22.01.9-2.5-2.42.4-2.2-2.12.32.3-2.02.0
Bone: maximum moment3.86.57.82.52.52.6-2.62.6-2.62.62.32.3-2.8-2.82.8-2.6-2.52.62.6-2.32.3
Mean time between licks in bursts0.20.20.30.30.30.4-0.60.6-0.60.50.60.6-0.5-0.50.5-0.4-0.50.40.4-0.50.5
Mean num. licks in bursts0.91.01.81.01.01.1-1.21.2-1.21.10.10.0-1.3-0.70.7-1.1-1.01.31.4-0.80.8
Cd content in liver0.50.62.0-0.5-0.5-0.60.8-0.80.8-0.8-1.3-1.40.50.7-0.70.70.7-0.3-0.30.6-0.6
Co content in liver1.82.12.5-1.5-1.5-1.61.5-1.51.5-1.6-1.3-1.31.61.2-1.21.61.5-1.5-1.51.4-1.4
Cu content in liver1.31.63.21.11.11.2-1.21.2-1.21.31.71.8-1.2-1.31.3-1.2-1.21.00.9-1.31.3
Fe content in liver0.30.40.8-0.4-0.4-0.50.5-0.50.5-0.5-0.3-0.30.60.8-0.80.60.7-0.8-0.90.8-0.8
K content in liver0.80.81.40.60.60.7-0.90.9-0.90.91.21.2-0.8-0.90.9-0.8-0.90.70.6-0.90.9
Mg content in liver0.10.10.7-0.1-0.10.0-0.20.2-0.20.20.80.80.0-0.30.3-0.1-0.20.0-0.0-0.30.3
Mn content in liver0.40.50.90.00.00.4-0.60.6-0.60.60.60.6-0.5-0.90.9-0.5-0.80.90.9-0.90.9
Na content in liver5.76.07.02.32.32.5-2.62.6-2.62.62.42.4-2.4-2.42.4-2.5-2.52.42.4-2.42.4
Rb content in liver0.00.00.10.10.10.1-0.30.3-0.30.20.10.2-0.00.1-0.0-0.1-0.1-0.0-0.10.0-0.0
Se content in liver3.44.26.2-2.5-2.5-2.22.1-2.12.1-2.1-2.0-2.01.92.0-2.02.12.0-1.8-1.71.8-1.8
Sr content in liver0.80.71.1-1.0-1.0-1.01.0-1.01.0-0.9-0.6-0.61.00.5-0.60.90.8-0.8-0.80.6-0.6
Zn content in liver0.30.30.6-0.6-0.6-0.60.7-0.70.7-0.6-0.1-0.10.70.4-0.50.60.6-0.7-0.80.5-0.5
Bone: minimum diameter5.310.013.43.23.23.2-3.23.2-3.23.22.22.1-3.3-3.33.3-3.2-3.23.63.7-3.13.1
Time in familiar zone, hab. session 10.30.30.50.60.60.6-0.70.7-0.70.60.20.2-0.7-0.40.4-0.6-0.50.60.6-0.40.4
Time in novel zone, hab. session 10.20.20.3-0.5-0.5-0.50.5-0.50.5-0.5-0.2-0.20.50.2-0.20.40.3-0.3-0.30.2-0.2
Total zone transitions, hab. session 10.60.81.40.90.90.9-1.11.1-1.11.00.0-0.1-0.7-0.90.9-0.9-1.01.11.2-0.70.7
Total locomotion distance, hab. session 13.14.45.92.42.42.3-2.32.3-2.32.11.00.9-2.1-2.01.9-2.2-2.12.42.4-1.91.9
Locomotion velocity, hab. session 11.31.92.71.61.61.5-1.51.5-1.51.40.40.3-1.3-1.31.3-1.4-1.41.61.7-1.31.3
Time in familiar zone, hab. session 20.40.40.80.90.90.7-0.50.5-0.50.60.60.6-0.6-0.60.6-0.6-0.50.60.6-0.70.7
Time in novel zone, hab. session 20.50.50.7-0.8-0.8-0.80.6-0.60.6-0.7-0.7-0.70.60.8-0.80.70.7-0.7-0.70.8-0.8
Total zone transitions, hab. session 20.00.10.3-0.5-0.5-0.40.1-0.10.1-0.2-0.2-0.20.20.1-0.10.30.1-0.1-0.00.1-0.1
Total locomotion distance, hab. session 20.40.50.90.60.60.6-0.80.8-0.80.70.40.3-0.9-0.80.7-0.7-0.80.90.9-0.80.8
Locomotion velocity, hab. session 20.30.40.80.50.50.5-0.70.7-0.70.60.30.3-0.8-0.70.7-0.6-0.70.80.9-0.80.8
Novel to familiar place preference ratio1.21.22.01.21.21.2-1.11.1-1.11.10.40.3-1.4-0.90.9-1.2-1.11.31.4-1.01.0
Novelty place preference1.11.11.81.11.11.2-1.11.1-1.11.10.50.4-1.3-0.90.9-1.2-1.01.21.3-0.90.9
Time in novel zone, NPP test0.60.71.20.80.80.9-0.80.8-0.80.80.20.2-1.1-0.60.7-0.9-0.81.01.0-0.70.7
Total zone transitions, NPP test0.10.20.3-0.3-0.3-0.30.2-0.20.2-0.3-0.5-0.40.40.5-0.50.30.4-0.5-0.50.5-0.5
Total locomotion distance, NPP test1.62.33.11.81.81.6-1.61.6-1.61.50.80.8-1.7-1.41.4-1.5-1.51.61.7-1.41.4
Locomotion velocity, NPP test2.13.03.92.02.01.8-1.81.8-1.81.71.11.0-1.9-1.61.6-1.8-1.71.91.9-1.61.6
Intraocular pressure0.10.10.30.00.0-0.00.4-0.40.4-0.20.00.10.30.3-0.30.10.3-0.4-0.50.6-0.5
Delta distance traveled before/after self-admin0.60.61.51.21.21.1-0.70.7-0.70.80.60.6-0.8-0.60.6-1.2-0.70.60.6-0.40.4
Delta ambulatory time before/after self-admin1.11.32.11.41.41.4-1.01.0-1.01.10.90.8-1.1-1.21.2-1.5-1.11.11.1-0.90.9
Parametrial fat weight0.51.01.5-1.2-1.2-1.11.0-1.01.0-1.0-0.6-0.51.20.9-0.91.01.0-1.1-1.11.0-0.9
Pavlov. Cond. lever latency0.20.20.4-0.3-0.3-0.40.7-0.70.7-0.6-0.5-0.50.30.5-0.40.40.5-0.4-0.40.5-0.5
Pavlov. Cond. magazine entry latency0.10.10.4-0.4-0.4-0.40.3-0.30.3-0.3-0.1-0.10.60.3-0.30.40.3-0.5-0.50.3-0.3
Pavlov. Cond. change in total contacts0.00.00.00.00.00.0-0.10.1-0.10.00.10.2-0.0-0.10.1-0.0-0.0-0.0-0.0-0.00.0
Pavlov. Cond. index score0.00.00.1-0.1-0.1-0.0-0.30.3-0.30.20.20.30.1-0.10.1-0.0-0.20.00.0-0.10.1
Pavlov. Cond. latency score0.10.10.20.10.10.2-0.40.4-0.40.40.40.4-0.0-0.30.3-0.2-0.30.20.2-0.30.3
Pavlov. Cond. lever contacts0.91.11.70.90.91.0-1.31.3-1.31.21.11.1-0.8-1.00.9-1.0-1.10.90.8-1.01.0
Pavlov. Cond. magazine entry number0.00.10.20.30.30.3-0.20.2-0.20.20.10.1-0.4-0.10.1-0.3-0.10.20.2-0.10.1
Pavlov. Cond. intertrial magazine entries0.20.20.4-0.6-0.6-0.40.5-0.50.5-0.4-0.6-0.6-0.10.3-0.30.40.4-0.2-0.20.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.00.00.1-0.50.5-0.50.40.50.5-0.1-0.40.4-0.2-0.40.20.2-0.40.4
Pavlov. Cond. response bias0.10.10.30.30.30.3-0.50.5-0.50.40.50.5-0.1-0.40.4-0.3-0.50.20.2-0.40.4
Pavlov. Cond. lever latency3.34.45.5-2.3-2.3-2.12.1-2.12.1-2.1-2.1-2.11.82.2-2.22.02.1-1.9-1.92.1-2.1
Pavlov. Cond. magazine entry latency2.02.34.21.71.71.5-1.51.5-1.51.52.02.0-1.4-1.51.5-1.5-1.41.01.0-1.31.3
Pavlov. Cond. change in total contacts6.28.510.33.23.22.9-2.92.9-2.92.92.72.6-2.7-3.03.0-2.9-2.92.92.9-2.92.9
Pavlov. Cond. index score3.14.05.12.32.32.0-2.12.1-2.12.02.12.2-1.7-2.02.0-1.9-2.01.61.6-1.81.8
Pavlov. Cond. latency score2.93.74.82.22.21.9-2.02.0-2.01.92.12.2-1.6-1.91.9-1.9-1.91.51.5-1.81.8
Pavlov. Cond. lever contacts3.14.35.22.32.32.1-2.12.1-2.12.12.02.0-1.8-2.22.2-2.0-2.11.91.9-2.02.0
Pavlov. Cond. magazine entry number1.31.62.6-1.6-1.6-1.41.3-1.31.3-1.3-1.5-1.61.11.1-1.11.21.1-0.8-0.71.0-1.0
Pavlov. Cond. intertrial magazine entries0.91.21.7-1.3-1.3-1.21.2-1.21.2-1.1-0.6-0.51.21.0-1.11.21.1-1.1-1.10.9-0.9
Pavlov. Cond. lever-magazine prob. diff.3.64.55.52.42.42.2-2.22.2-2.22.22.32.3-1.9-2.22.2-2.1-2.11.81.7-2.02.0
Pavlov. Cond. response bias3.64.95.92.42.42.2-2.22.2-2.22.22.22.2-1.9-2.32.3-2.1-2.22.02.0-2.22.2
Time in closed arm before self-admin0.20.30.7-0.8-0.8-0.80.6-0.60.6-0.7-0.3-0.30.70.2-0.20.70.3-0.1-0.1-0.00.0
Time in closed arm after self-admin0.30.30.70.20.20.3-0.60.6-0.60.50.80.9-0.1-0.50.5-0.2-0.60.10.1-0.60.6
Time in open arm before self-admin1.41.62.21.41.41.5-1.31.3-1.31.41.21.2-1.5-1.01.0-1.4-1.11.11.1-0.90.9
Time in open arm after self-admin0.70.81.50.80.80.9-0.80.8-0.80.90.70.7-1.2-1.01.0-0.9-0.81.21.2-0.70.7
Bone: periosteal estimation2.04.24.92.12.12.1-2.12.1-2.12.11.61.6-2.2-2.12.1-2.1-2.02.22.2-1.81.8
Bone: periosteal perimeter1.82.93.61.91.91.9-1.81.8-1.81.81.41.3-1.8-1.71.7-1.8-1.71.81.8-1.51.5
Bone: post-yield work0.71.01.51.21.21.1-0.90.9-0.90.90.60.5-1.2-1.01.0-1.0-1.01.01.0-1.00.9
Progressive ratio test 1 active lever presses1.81.94.00.70.70.5-1.11.1-1.11.11.92.0-0.6-2.02.0-0.8-1.61.11.1-1.81.8
Progressive ratio test 1 breakpoint2.22.34.40.90.90.7-1.41.4-1.41.42.12.1-0.8-2.02.0-1.0-1.81.31.3-1.91.9
Progressive ratio test 1 inactive lever presses0.40.51.40.80.80.7-0.40.4-0.40.51.11.2-0.1-1.01.0-0.5-0.70.20.2-0.60.6
Progressive ratio test 2 active lever presses0.80.82.10.70.70.5-0.80.8-0.80.81.41.5-0.3-1.21.2-0.6-1.00.50.5-1.01.0
Progressive ratio test 2 breakpoint0.80.92.50.70.70.5-0.80.8-0.80.81.51.6-0.3-1.31.3-0.6-1.10.50.5-1.11.0
Progressive ratio test 2 inactive lever presses2.83.25.21.91.91.7-1.71.7-1.71.72.22.3-1.6-2.01.9-1.6-1.71.41.4-1.71.7
Incentive Sensitization - Responses0.00.00.20.30.30.0-0.20.2-0.20.20.40.4-0.00.0-0.0-0.1-0.1-0.3-0.30.2-0.3
Incentive Sensitization - Breakpoint0.10.10.20.10.1-0.10.0-0.00.0-0.00.10.20.10.3-0.30.10.1-0.4-0.50.4-0.5
Sum of active levers in priming session hrs 5-60.20.21.40.00.00.1-0.10.1-0.10.0-1.1-1.2-0.5-0.10.1-0.1-0.00.60.8-0.00.0
Progressive ratio0.40.51.3-0.3-0.3-0.10.6-0.60.6-0.6-1.1-1.20.30.8-0.80.40.8-0.6-0.60.9-0.8
Food seeking constrained by brief footshock2.83.54.42.02.02.0-1.81.8-1.81.71.41.3-1.8-2.02.0-1.8-2.02.12.1-1.91.9
Seeking ratio, punishment vs. effort1.82.23.61.21.21.0-1.31.3-1.31.31.91.9-1.0-1.81.8-1.1-1.71.51.4-1.81.7
Retroperitoneal fat weight0.93.04.3-1.9-1.9-1.81.5-1.51.5-1.5-1.4-1.41.72.0-2.11.71.8-1.8-1.81.9-2.0
Reaction time number correct0.00.10.1-0.2-0.2-0.0-0.10.1-0.10.10.30.30.1-0.30.3-0.1-0.30.30.3-0.40.4
Reaction time mean minus median0.20.20.70.40.40.4-0.50.5-0.50.50.80.8-0.3-0.40.4-0.4-0.50.40.4-0.60.5
Reaction time mean minus median AUC0.30.41.40.50.50.5-0.70.7-0.70.61.11.2-0.4-0.60.6-0.6-0.70.40.4-0.70.5
Reaction time num false alarms0.81.11.6-1.3-1.3-1.11.0-1.01.0-1.0-1.2-1.21.30.3-0.31.01.0-1.0-1.01.1-1.0
Reaction time num false alarms AUC1.11.52.3-1.5-1.5-1.31.2-1.21.2-1.3-1.4-1.41.50.5-0.61.31.1-1.2-1.21.3-1.2
Reaction time trials correct on left0.00.10.1-0.2-0.2-0.0-0.10.1-0.10.10.30.30.1-0.30.3-0.1-0.30.30.3-0.40.4
Reaction time trials on left0.00.00.1-0.2-0.2-0.1-0.00.0-0.00.10.30.30.1-0.20.3-0.0-0.30.30.3-0.30.3
Reaction time mean0.10.10.3-0.3-0.3-0.30.3-0.30.3-0.30.20.20.60.1-0.20.30.2-0.4-0.50.0-0.1
Reaction time mean AUC0.20.20.7-0.6-0.6-0.50.4-0.40.4-0.40.20.30.80.2-0.30.50.3-0.7-0.70.2-0.3
Median of all reaction times0.20.20.6-0.6-0.6-0.50.5-0.50.5-0.5-0.1-0.10.80.3-0.30.50.4-0.6-0.70.2-0.3
Reaction time omissions0.20.30.7-0.8-0.8-0.70.5-0.50.5-0.5-0.3-0.30.80.1-0.20.60.3-0.4-0.40.2-0.3
Reaction time false alarm rate1.01.31.8-1.2-1.2-1.11.1-1.11.1-1.2-1.3-1.31.30.6-0.71.11.2-1.3-1.31.3-1.3
Reaction time premature initiation rate0.00.00.10.20.20.10.0-0.00.0-0.0-0.1-0.1-0.00.1-0.1-0.00.10.10.10.1-0.1
Reaction time premature initiations0.00.00.00.00.00.00.0-0.00.0-0.0-0.0-0.00.0-0.0-0.0-0.0-0.00.20.2-0.00.0
Std. dev. reaction times0.10.10.70.10.10.2-0.20.2-0.20.20.80.80.0-0.40.3-0.2-0.40.20.1-0.50.4
Reaction time trials completed0.00.00.1-0.2-0.2-0.1-0.00.0-0.00.10.30.30.1-0.20.3-0.0-0.30.30.3-0.30.3
Reaction time trials AUC0.00.00.1-0.4-0.4-0.20.1-0.10.1-0.00.20.20.2-0.20.20.1-0.20.20.2-0.30.3
Run reversals in cocaine runway, females0.30.31.0-0.4-0.4-0.40.5-0.50.5-0.50.20.30.70.5-0.60.40.5-0.9-1.00.6-0.6
Run reversals in cocaine runway, males1.31.32.7-1.4-1.4-1.61.2-1.21.2-1.2-0.9-0.91.20.9-0.91.31.1-0.8-0.80.8-0.8
Latency to leave start box in cocaine runway0.10.10.4-0.1-0.1-0.10.2-0.20.2-0.1-0.2-0.2-0.20.5-0.5-0.10.6-0.3-0.30.6-0.5
Latency to leave start box in cocaine runway, F0.50.61.0-0.7-0.7-0.80.8-0.80.8-0.7-0.9-0.90.40.9-0.90.31.0-0.6-0.60.9-0.8
Latency to leave start box in cocaine runway, M0.10.10.30.30.30.4-0.20.2-0.20.20.50.5-0.3-0.20.2-0.2-0.10.10.1-0.10.0
Std. dev. time between licks in bursts0.70.81.40.90.91.0-1.11.1-1.11.00.50.4-1.2-0.80.8-1.0-0.80.91.0-0.70.7
Total sessions with >9 infusions0.20.20.8-0.9-0.9-0.70.2-0.20.2-0.20.00.00.7-0.60.60.2-0.30.00.0-0.50.4
Short access day 1 total inactive lever presses0.50.51.10.90.90.8-0.70.7-0.70.71.01.1-0.5-0.70.7-0.7-0.70.40.4-0.50.5
Short access day 10 total inactive lever presses0.30.41.11.01.01.1-0.50.5-0.50.50.80.8-0.4-0.40.4-0.5-0.50.10.1-0.30.4
Short access day 1 total infusions0.30.40.90.00.0-0.0-0.40.4-0.40.40.90.90.0-0.90.9-0.2-0.70.50.5-0.90.8
Short access day 10 total infusions0.20.30.9-0.7-0.7-0.70.6-0.60.6-0.60.10.10.9-0.20.20.60.1-0.4-0.4-0.20.1
Short access total infusions0.30.31.2-0.8-0.8-0.80.5-0.50.5-0.50.10.21.1-0.30.30.60.0-0.4-0.4-0.20.1
Short access day 1 locomotion1.11.21.9-1.4-1.4-1.10.9-0.90.9-1.0-1.2-1.21.30.8-0.81.10.9-1.1-1.11.2-1.1
Short access day 10 total locomotion0.70.71.50.70.70.9-0.90.9-0.90.80.80.8-0.4-1.21.2-0.8-1.00.50.5-1.01.0
Short access total locomotion0.10.10.6-0.5-0.5-0.20.1-0.10.1-0.2-0.1-0.10.8-0.50.50.2-0.1-0.4-0.4-0.00.0
One hour access (0.3 mA shock)1.51.82.61.41.41.4-1.31.3-1.31.31.31.3-0.9-1.51.5-1.2-1.51.11.1-1.61.4
Compulsive drug intake0.30.30.70.70.70.8-0.40.4-0.40.4-0.0-0.1-0.6-0.50.5-0.5-0.50.70.8-0.60.4
One hour access (shock baseline)0.30.30.90.40.40.3-0.50.5-0.50.50.90.9-0.1-0.60.6-0.4-0.70.20.2-0.70.7
Social response proportion4.44.87.11.91.91.9-2.12.1-2.12.12.32.2-2.0-2.22.2-2.0-2.42.32.3-2.72.6
Social responses0.10.10.50.40.40.3-0.40.4-0.40.40.70.7-0.2-0.00.0-0.3-0.40.10.1-0.50.3
Social time0.30.41.11.01.00.8-0.60.6-0.60.70.30.3-0.8-0.10.1-0.8-0.70.70.8-0.60.5
Soleus weight0.92.65.1-1.4-1.4-1.51.4-1.41.4-1.6-2.2-2.31.51.8-1.81.51.6-1.3-1.31.6-1.6
Bone: stiffness1.42.23.01.51.51.5-1.41.4-1.41.41.11.0-1.7-1.71.7-1.5-1.41.71.7-1.41.4
Tibialis anterior weight0.00.10.4-0.1-0.10.0-0.30.3-0.30.1-0.6-0.7-0.1-0.00.1-0.1-0.20.30.3-0.10.1
Time to tail flick, vehicle, before self-admin0.20.20.60.10.10.4-0.70.7-0.70.60.70.8-0.3-0.40.4-0.6-0.40.20.1-0.30.3
Time to tail flick, vehicle, after self-admin0.20.20.80.40.40.2-0.20.2-0.20.20.80.9-0.2-0.50.50.1-0.30.20.2-0.50.5
Time to tail flick, test, before self-admin0.10.10.3-0.2-0.20.2-0.50.5-0.50.40.10.1-0.4-0.20.2-0.4-0.30.20.2-0.00.0
Time to tail flick, test, after self-admin0.00.00.1-0.1-0.10.1-0.20.2-0.20.10.30.30.1-0.30.3-0.4-0.30.00.0-0.20.2
Delta time to tail flick, vehicle, before/after SA0.10.10.20.20.20.10.0-0.00.00.00.30.3-0.2-0.30.30.2-0.30.30.2-0.40.4
Delta time to tail flick, test, before/after SA0.00.00.1-0.1-0.1-0.10.3-0.30.3-0.20.20.20.3-0.10.10.10.0-0.1-0.1-0.20.2
Tibia length2.16.07.52.32.32.4-2.52.5-2.52.52.72.7-2.2-2.62.6-2.4-2.52.22.2-2.32.3
Ambulatory time before self-admin1.01.01.30.90.90.8-1.01.0-1.01.01.00.9-1.0-1.11.1-0.5-1.01.11.1-1.11.1
Ambulatory time after self-admin5.35.97.32.72.72.5-2.22.2-2.22.32.42.4-2.4-2.52.5-2.4-2.42.42.4-2.52.5
Bone: tissue strength4.34.25.02.12.12.1-1.91.9-1.92.01.91.9-2.0-2.22.2-2.1-2.12.12.1-2.12.1
Total heroin consumption1.41.73.81.41.41.3-1.21.2-1.21.20.1-0.1-1.7-1.31.3-1.1-1.21.81.9-1.31.3
Bone: trabecular number0.10.20.50.40.40.5-0.60.6-0.60.50.50.5-0.7-0.40.4-0.5-0.40.20.2-0.10.1
Bone: trabecular spacing1.62.12.91.51.51.4-1.41.4-1.41.41.11.0-1.3-1.51.5-1.5-1.51.71.7-1.61.6
Bone: trabecular thickness0.20.20.5-0.6-0.6-0.50.3-0.30.3-0.30.20.30.40.4-0.40.40.5-0.7-0.70.6-0.6
Bone: trabecular tissue density2.63.74.1-1.9-1.9-1.91.9-1.91.9-1.9-2.0-1.91.82.0-2.01.92.0-1.8-1.82.0-2.0
Water consumed over 24 hours0.81.01.70.70.70.9-1.01.0-1.01.01.31.3-0.8-1.01.0-1.0-1.00.90.9-1.11.1
Number of responses in last shaping day2.12.12.71.11.11.2-1.51.5-1.51.51.71.6-1.7-1.51.5-1.4-1.51.61.5-1.51.5