Hub : Genes

Ece1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_006239275.4 0.02 0.02 9.9e-03 0.01 0.01 0 0.01 2.0e-02 2.6e-02 8.1e-02 4.8e-02
2 Liver gene expression Ece1 0.04 0.05 4.9e-04 0.02 0.02 0.02 0.02 2.9e-03 1.4e-03 6.6e-03 5.8e-03
3 PL gene expression Ece1 0.1 0.08 3.9e-09 0.08 0.08 0.08 0.08 8.7e-09 5.3e-09 1.0e-08 1.0e-08
4 NAcc gene expression Ece1 0.17 0.11 0.0e+00 0.16 0.17 0.16 0.17 2.1e-18 2.5e-19 1.2e-18 5.5e-19
5 Adipose intron excision ratio chr5_150133272_150133824 0.03 0.03 7.7e-04 0.02 0.02 0.03 0.02 1.0e-03 2.5e-03 6.7e-04 1.6e-03
6 BLA gene expression Ece1 0.13 0.09 2.9e-06 0.08 0.09 0.08 0.08 3.3e-05 9.9e-06 5.0e-05 4.4e-05
7 Adipose intron excision ratio chr5_150126242_150133824 0.03 0.03 5.8e-04 0.02 0.02 0.03 0.02 1.2e-03 1.9e-03 4.8e-04 1.2e-03
8 Adipose isoform ratio XM_006239275.4 0.03 0.03 2.3e-04 0.03 0.03 0.03 0.02 6.4e-04 3.8e-04 7.7e-04 1.8e-03
9 pVTA intron excision ratio chr5_150133272_150133824 0.09 0.1 8.8e-03 0.01 0.04 0.01 0.01 1.4e-01 1.1e-02 9.3e-02 9.0e-02
10 pVTA intron excision ratio chr5_150126242_150133824 0.09 0.1 8.5e-03 0 0.04 0.01 0.01 3.2e-01 1.0e-02 7.4e-02 7.7e-02
11 pVTA gene expression Ece1 0.22 0.14 2.5e-08 0.18 0.16 0.15 0.18 2.8e-08 2.9e-07 6.7e-07 4.5e-08
12 OFC gene expression Ece1 0.26 0.23 8.3e-04 0.12 0.12 0.1 0.12 8.2e-04 1.1e-03 1.9e-03 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.10.1-0.40.40.40.40.30.3-0.30.3-0.30.3-0.2-0.4
Area under the delay curve0.50.50.6-0.80.70.70.70.70.8-0.70.8-0.80.8-0.5-0.7
BMI with tail0.00.10.30.3-0.4-0.5-0.4-0.3-0.30.3-0.20.1-0.10.60.2
BMI without tail0.40.71.00.9-0.8-0.8-0.8-0.9-0.80.9-0.80.8-0.81.00.9
Body weight2.08.611.42.8-2.9-2.9-2.9-2.8-2.92.8-2.93.0-3.03.42.7
Weight adjusted by age1.41.62.01.4-1.2-1.2-1.2-1.4-1.21.4-1.21.1-1.11.11.3
Bone surface0.00.00.0-0.10.10.10.10.10.1-0.10.1-0.00.00.2-0.0
Bone volume0.00.10.1-0.30.30.40.30.20.2-0.20.2-0.20.2-0.1-0.2
Breakpoint value in progressive ratio session1.61.81.91.4-1.4-1.4-1.4-1.4-1.41.4-1.31.3-1.31.11.2
Number of licking bursts0.00.00.00.1-0.2-0.2-0.2-0.1-0.20.1-0.20.1-0.1-0.20.1
Context. condit. distance diff. score0.80.91.11.0-1.0-1.0-1.0-1.0-1.01.0-0.90.9-0.90.90.9
Locomotion velocity, session 12.02.12.4-1.51.51.51.51.51.5-1.51.5-1.51.5-1.2-1.3
Locomotion distance, session 12.53.23.4-1.81.81.81.81.81.8-1.81.8-1.81.8-1.7-1.8
Locomotion velocity, session 24.45.25.8-2.42.32.32.32.32.3-2.32.3-2.22.2-2.4-2.0
Locomotion distance, session 21.21.61.9-1.41.41.41.31.31.3-1.31.3-1.21.2-1.1-1.1
Locomotion velocity, session 31.21.42.4-1.21.11.11.11.21.2-1.21.2-1.31.3-1.6-0.9
Locomotion distance, session 30.50.60.70.8-0.8-0.8-0.8-0.7-0.80.7-0.80.7-0.70.60.6
Stereotopy head waving bouts, day 31.51.82.1-1.41.41.41.51.41.4-1.41.4-1.31.3-0.8-1.1
Stereotopy head waving duration, day 30.70.81.1-1.01.01.01.00.91.0-0.90.9-0.90.9-0.4-0.7
Locomotion velocity, session 72.32.62.81.7-1.7-1.7-1.7-1.7-1.61.7-1.61.6-1.61.41.3
Locomotion distance, session 70.30.40.50.7-0.6-0.6-0.6-0.7-0.60.7-0.60.6-0.60.60.3
Stereotopy head waving bouts, day 70.10.10.30.1-0.2-0.2-0.2-0.1-0.20.1-0.20.1-0.10.60.3
Stereotopy head waving duration, day 70.10.10.20.2-0.2-0.3-0.3-0.2-0.30.2-0.30.3-0.30.50.4
Locomotion velocity, session 81.01.21.4-1.11.11.11.11.01.1-1.01.1-1.21.2-1.2-0.5
Locomotion distance, session 80.00.00.0-0.0-0.0-0.0-0.0-0.00.00.00.0-0.10.10.10.0
Degree of sensitization distance0.30.30.5-0.60.60.70.70.50.6-0.50.6-0.50.5-0.5-0.6
Degree of sensitization stereotypy1.41.51.81.2-1.3-1.3-1.3-1.2-1.31.2-1.31.2-1.21.31.3
Conditioned locomotion1.61.92.3-1.31.41.31.41.31.4-1.31.4-1.41.4-1.5-1.4
Cocaine response after cond. corrected0.00.00.1-0.20.20.20.20.20.2-0.20.2-0.20.2-0.2-0.1
Cocaine response after cond. not corrected0.00.00.10.1-0.2-0.2-0.2-0.1-0.20.1-0.20.1-0.10.20.3
Cocaine response before conditioning1.21.41.61.1-1.2-1.2-1.2-1.1-1.21.1-1.21.3-1.31.21.2
Saline control response0.00.00.1-0.10.10.00.10.10.2-0.10.2-0.30.3-0.2-0.0
Bone: connectivity density0.00.10.10.2-0.3-0.3-0.3-0.3-0.30.3-0.30.3-0.30.30.3
Bone: cortical apparent density2.43.23.51.8-1.9-1.8-1.9-1.9-1.81.9-1.81.8-1.81.51.4
Bone: cortical area0.71.11.31.0-0.9-0.9-0.9-1.1-1.01.1-1.01.1-1.11.11.1
Bone: cortical porosity0.91.01.2-1.11.11.11.11.01.0-1.01.0-0.90.9-0.9-1.0
Bone: cortical porosity1.92.02.4-1.51.51.51.51.41.4-1.41.4-1.31.3-1.2-1.5
Bone: cortical thickness0.60.91.01.0-1.0-0.9-1.0-1.0-1.01.0-1.01.0-1.00.91.0
Bone: cortical thickness0.10.20.7-0.30.30.30.30.30.4-0.30.4-0.40.4-0.8-0.3
Bone: cortical tissue density2.22.93.21.8-1.8-1.8-1.8-1.8-1.81.8-1.81.7-1.71.41.4
Condit. Reinf. active minus inactive responses0.40.40.6-0.70.70.70.70.70.6-0.70.6-0.50.5-0.5-0.8
Condit. Reinf. active-inactive response ratio0.10.10.2-0.40.40.40.40.30.3-0.30.3-0.20.2-0.3-0.4
Condit. Reinf. active responses0.30.40.6-0.70.70.70.70.70.6-0.70.5-0.40.4-0.3-0.7
Condit. Reinf. inactive responses0.20.20.3-0.50.50.60.50.60.4-0.60.4-0.30.3-0.0-0.4
Incentive salience index mean0.30.30.5-0.60.60.70.70.60.5-0.60.5-0.40.4-0.6-0.7
Condit. Reinf. lever presses0.10.10.2-0.30.30.40.30.30.2-0.30.2-0.00.0-0.5-0.4
Condit. Reinf. active minus inactive responses0.10.20.2-0.40.40.40.40.40.4-0.40.4-0.50.5-0.5-0.2
Condit. Reinf. active-inactive response ratio0.90.91.0-1.00.90.90.90.91.0-0.91.0-1.01.0-0.9-0.9
Condit. Reinf. active responses0.00.00.10.1-0.1-0.1-0.1-0.2-0.10.2-0.20.2-0.2-0.10.3
Condit. Reinf. inactive responses0.80.91.21.0-0.9-0.8-0.9-1.0-1.01.0-1.01.1-1.10.71.0
Condit. Reinf. lever presses0.60.91.1-0.91.01.01.00.90.9-0.90.9-0.80.8-0.9-1.0
Condit. Reinf. lever reinforcers received0.00.00.00.1-0.0-0.0-0.1-0.1-0.10.1-0.10.1-0.1-0.00.2
Conditioned reinforcement - actives0.30.30.30.6-0.4-0.4-0.4-0.5-0.50.5-0.50.5-0.50.50.6
Conditioned reinforcement - inactives0.20.20.50.3-0.4-0.4-0.4-0.4-0.40.4-0.40.5-0.50.70.5
Conditioned locomotion1.21.41.71.3-1.1-1.1-1.1-1.2-1.21.2-1.21.2-1.21.11.3
Patch foraging indifference point 0 sec0.10.10.70.4-0.2-0.3-0.3-0.3-0.30.3-0.30.2-0.20.20.9
Patch foraging indifference point AUC1.41.62.21.5-1.3-1.3-1.3-1.4-1.31.4-1.21.2-1.20.81.2
Delay disc. indifference point, 0s delay1.51.61.7-1.31.31.21.31.31.3-1.31.3-1.31.3-0.9-1.3
Delay disc. indifference point, 16s delay0.00.00.00.00.00.10.0-0.00.00.00.0-0.00.0-0.00.0
Delay disc. indifference point, 2s delay0.20.20.4-0.50.50.40.50.50.5-0.50.5-0.50.5-0.3-0.6
Delay disc. indifference point, 24s delay0.00.00.1-0.10.20.20.20.10.1-0.10.1-0.10.1-0.3-0.1
Delay disc. indifference point, 4s delay0.60.60.7-0.80.80.80.80.80.8-0.80.8-0.80.8-0.1-0.8
Delay disc. indifference point, 8s delay0.40.40.5-0.70.60.60.60.60.7-0.60.7-0.70.7-0.6-0.5
Indifference point function ln k4.96.97.8-2.62.82.82.82.52.7-2.52.7-2.62.6-2.3-2.5
Indifference point function log k4.96.97.8-2.62.82.82.82.52.7-2.52.7-2.62.6-2.3-2.5
Patch foraging total patch changes 0 sec0.00.00.40.2-0.0-0.1-0.1-0.1-0.00.1-0.1-0.00.0-0.10.6
Patch foraging total patch changes 12 sec1.92.54.21.7-1.5-1.5-1.5-1.6-1.51.6-1.51.5-1.51.42.0
Patch foraging total patch changes 18 sec1.11.41.81.3-1.1-1.1-1.2-1.2-1.21.2-1.21.2-1.21.01.4
Patch foraging total patch changes 24 sec1.21.51.91.3-1.3-1.3-1.3-1.2-1.21.2-1.21.1-1.11.11.4
Patch foraging total patch changes 6 sec3.45.17.42.3-2.2-2.2-2.2-2.3-2.22.3-2.22.1-2.12.12.7
Patch foraging time to switch 0 sec1.21.92.21.3-1.4-1.4-1.4-1.3-1.41.3-1.41.4-1.41.51.3
Patch foraging water rate 0 sec1.93.03.3-1.71.71.71.71.71.8-1.71.8-1.81.8-1.7-1.5
Patch foraging water rate 12 sec1.92.83.1-1.61.61.61.61.61.7-1.61.7-1.81.8-1.8-1.8
Patch foraging water rate 18 sec1.62.22.8-1.61.61.71.61.51.5-1.51.5-1.41.4-1.4-1.2
Patch foraging water rate 24 sec2.83.94.4-2.12.02.02.02.12.0-2.12.0-2.02.0-1.6-1.8
Patch foraging water rate 6 sec3.44.95.3-2.32.22.22.22.32.2-2.32.2-2.32.3-2.2-2.0
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.30.20.10.20.30.3-0.30.3-0.40.40.0-0.4
Distance traveled before self-admin7.68.08.83.0-2.9-2.9-2.9-2.9-2.92.9-2.92.9-2.92.42.6
Distance traveled after self-admin2.83.13.31.8-1.8-1.8-1.8-1.7-1.81.7-1.81.8-1.81.71.5
Extensor digitorum longus weight0.20.81.0-0.90.90.90.90.90.9-0.90.9-1.01.0-0.8-1.0
Bone: elastic displacement0.10.10.1-0.30.20.30.30.30.2-0.30.2-0.20.20.0-0.2
Bone: elastic work0.00.00.00.1-0.1-0.1-0.1-0.0-0.10.0-0.00.1-0.10.1-0.1
Bone: endosteal estimation0.20.50.70.7-0.5-0.4-0.5-0.7-0.70.7-0.70.8-0.80.80.7
Bone: endosteal perimeter0.10.30.6-0.60.70.70.70.50.6-0.50.5-0.40.4-0.2-0.5
Epididymis fat weight0.00.00.1-0.20.00.10.10.20.1-0.20.1-0.10.10.1-0.4
Delta time in closed arm before/after self-admin0.10.10.2-0.30.40.40.40.30.3-0.20.3-0.20.2-0.10.0
Delta time in open arm before/after self-admin0.20.20.40.4-0.4-0.4-0.4-0.3-0.40.3-0.40.4-0.40.70.1
Diff in mean of infusions in LGA sessions0.00.00.0-0.10.10.10.10.10.1-0.10.1-0.00.0-0.0-0.1
Delay discount exponential model param0.40.40.50.7-0.7-0.6-0.7-0.7-0.70.6-0.70.7-0.70.40.6
Extinction: sum of active levers before priming0.60.61.00.8-0.7-0.7-0.7-0.7-0.80.7-0.80.8-0.81.00.6
Active lever presses in extinction session 60.30.30.50.5-0.5-0.5-0.5-0.5-0.50.5-0.50.6-0.60.70.3
Bone: final force1.32.22.71.6-1.5-1.4-1.5-1.6-1.51.6-1.51.5-1.51.21.2
Bone: final moment0.91.51.81.3-1.2-1.2-1.2-1.3-1.21.3-1.21.3-1.31.00.9
Food consumed during 24 hour testing period1.21.52.21.2-1.2-1.2-1.2-1.2-1.21.2-1.21.1-1.11.31.5
Glucose3.95.96.52.5-2.5-2.5-2.5-2.4-2.42.4-2.42.3-2.32.42.3
Heart weight1.82.63.51.5-1.7-1.7-1.6-1.5-1.61.5-1.61.5-1.51.91.8
Delay discount hyperbolic model param0.40.50.50.7-0.7-0.7-0.7-0.7-0.70.7-0.70.7-0.70.40.7
Intermittent access intake day 1-15 change0.50.50.7-0.80.70.70.70.80.6-0.80.6-0.60.6-0.7-0.9
Intermittent access intake escalation0.40.40.6-0.70.60.70.60.70.5-0.70.5-0.40.4-0.6-0.8
Intermittent access intake escalation 20.50.50.6-0.80.70.80.70.80.6-0.80.6-0.50.5-0.7-0.8
Intermitt. access day 1 inactive lever presses4.24.55.22.3-2.0-2.0-2.0-2.3-2.12.3-2.12.1-2.11.92.2
Intermitt. access day 15 inactive lever presses1.61.82.11.3-1.3-1.3-1.3-1.4-1.41.4-1.41.4-1.41.01.3
Intermitt. access escalation Index0.10.10.20.1-0.5-0.5-0.4-0.1-0.30.1-0.30.2-0.20.30.1
Intermittent access day 1 total infusions5.86.77.32.7-2.6-2.6-2.6-2.7-2.62.7-2.62.5-2.52.52.7
Intermittent access day 15 total infusions2.52.83.01.7-1.6-1.6-1.6-1.7-1.71.7-1.71.7-1.71.51.6
Intermittent access terminal intake (last 3 days)1.71.82.21.4-1.3-1.3-1.3-1.3-1.41.3-1.41.5-1.51.11.3
Intermittent access total infusions3.13.53.71.9-1.9-1.9-1.9-1.9-1.91.9-1.91.9-1.91.61.9
Intermittent access day 1 locomotion0.10.10.30.5-0.3-0.3-0.3-0.5-0.20.5-0.30.2-0.20.40.4
Intermittent access day 15 total locomotion0.10.10.2-0.40.40.40.40.40.3-0.40.3-0.30.3-0.0-0.4
Intermittent access total locomotion0.10.20.20.4-0.4-0.4-0.4-0.4-0.40.4-0.40.4-0.40.40.4
Intermittent access standard deviation1.31.41.81.2-1.1-1.1-1.1-1.2-1.11.2-1.11.2-1.21.41.1
Left kidney weight10.128.435.55.3-5.3-5.2-5.2-5.3-5.35.3-5.35.3-5.36.05.2
Right kidney weight5.214.519.03.7-3.8-3.8-3.8-3.7-3.83.7-3.83.8-3.84.43.7
Cocaine induced anxiety0.00.00.10.2-0.1-0.1-0.1-0.2-0.20.2-0.20.3-0.30.20.2
Post-drug Anxiety2.22.52.6-1.61.61.61.61.61.5-1.61.5-1.51.5-1.5-1.6
Baseline Anxiety3.84.04.5-2.11.91.81.92.12.0-2.12.0-2.12.1-1.9-2.1
Tail length1.64.86.02.2-2.0-1.9-2.0-2.2-2.22.2-2.22.4-2.42.42.1
Length with tail2.710.011.93.1-3.1-3.0-3.1-3.1-3.23.1-3.23.4-3.43.42.9
Length without tail1.53.24.01.7-1.9-1.8-1.8-1.7-1.81.6-1.81.9-1.82.01.5
Times rat made contact with spout0.40.50.60.7-0.7-0.7-0.7-0.7-0.70.7-0.70.6-0.60.30.8
Lifetime Intake2.62.93.11.8-1.7-1.7-1.7-1.7-1.71.7-1.71.8-1.81.51.7
Liver weight, left2.74.24.82.1-1.9-1.8-1.9-2.1-2.02.1-2.12.2-2.22.12.2
Liver weight, right2.44.04.62.1-1.9-1.9-2.0-2.0-2.02.0-2.02.0-2.01.92.1
Locomotor activity1.01.62.81.0-1.3-1.3-1.3-1.1-1.21.1-1.31.2-1.21.41.7
Locomotor testing distance0.50.81.30.6-0.9-0.9-0.9-0.6-0.90.7-0.90.8-0.91.11.1
Locomotor testing rearing0.50.81.30.8-0.9-0.9-0.9-0.8-0.90.8-0.90.9-0.90.91.1
Locomotion in novel chamber0.30.30.80.3-0.8-0.9-0.7-0.4-0.50.4-0.50.3-0.30.90.6
Locomotion in novel chamber post-restriction0.00.00.20.0-0.1-0.0-0.00.0-0.1-0.0-0.10.1-0.10.5-0.1
Fecal boli incidents, locomotor time 15.15.67.82.5-2.4-2.3-2.3-2.2-2.42.2-2.32.4-2.42.82.1
Change in fecal boli incidents, locomotor task5.55.26.9-2.22.32.22.32.12.3-2.12.3-2.42.4-2.6-2.1
Time >=10cm from walls, locomotor time 12.82.83.41.7-1.9-1.8-1.8-1.5-1.81.5-1.81.8-1.81.51.4
Bouts of movement, locomotor time 10.00.00.1-0.00.0-0.00.00.20.2-0.20.2-0.30.3-0.20.1
Total resting periods, locomotor time 10.00.00.10.1-0.1-0.2-0.10.0-0.0-0.0-0.0-0.10.10.00.3
Rest time, locomotor task time 10.91.01.91.0-1.0-1.1-1.0-0.8-0.90.8-0.90.8-0.81.41.0
Distance moved, locomotor task time 10.70.71.2-1.10.80.90.80.70.8-0.70.8-0.80.8-1.1-0.8
Vertical activity count, locomotor time 11.61.62.1-1.41.31.31.31.21.2-1.21.2-1.21.2-1.4-1.2
Time >=10cm from walls, locomotor time 22.42.53.21.8-1.7-1.7-1.7-1.7-1.61.7-1.51.5-1.51.21.4
Bouts of movement, locomotor time 20.00.00.10.0-0.0-0.0-0.00.20.1-0.20.1-0.20.2-0.2-0.0
Total resting periods, locomotor time 20.10.10.1-0.10.10.10.10.30.2-0.30.2-0.30.3-0.3-0.2
Rest time, locomotor task time 20.91.01.61.0-1.1-1.1-1.1-0.7-1.00.7-1.01.0-1.01.30.8
Distance moved, locomotor task time 20.00.00.1-0.30.20.20.2-0.00.20.00.2-0.10.1-0.2-0.2
Vertical activity count, locomotor time 20.40.51.1-0.80.70.80.70.50.7-0.50.7-0.60.6-1.1-0.5
Light reinforcement 10.30.60.80.8-0.8-0.8-0.8-0.9-0.80.9-0.80.7-0.70.30.9
Light reinforcement 20.00.00.1-0.1-0.0-0.1-0.10.00.0-0.00.1-0.20.2-0.3-0.3
Bone: marrow area0.20.50.70.7-0.5-0.4-0.5-0.7-0.70.7-0.70.8-0.80.80.7
Bone: maximum diameter0.20.50.60.7-0.6-0.5-0.5-0.7-0.70.7-0.70.8-0.80.70.8
Bone: maximum force0.71.11.41.1-1.0-1.0-1.0-1.2-1.11.2-1.11.2-1.20.80.9
Bone: maximum moment0.30.60.80.8-0.7-0.6-0.7-0.8-0.80.8-0.80.9-0.90.60.6
Mean time between licks in bursts0.71.01.8-0.91.01.01.00.91.0-0.91.0-1.01.0-1.1-1.4
Mean num. licks in bursts0.30.40.60.6-0.5-0.5-0.5-0.6-0.50.6-0.50.6-0.60.70.7
Cd content in liver0.50.60.80.8-0.9-0.9-0.8-0.8-0.80.8-0.70.7-0.70.70.7
Co content in liver0.10.20.2-0.50.40.40.50.40.4-0.40.4-0.30.3-0.0-0.4
Cu content in liver0.00.00.10.2-0.3-0.3-0.3-0.2-0.20.2-0.20.2-0.20.10.1
Fe content in liver0.70.81.1-0.90.90.90.90.90.9-0.90.9-0.90.9-1.0-0.8
K content in liver0.10.10.3-0.30.30.30.30.30.3-0.30.3-0.40.4-0.5-0.2
Mg content in liver0.10.10.20.4-0.4-0.5-0.4-0.4-0.40.4-0.40.3-0.30.20.5
Mn content in liver0.00.00.10.2-0.1-0.1-0.2-0.2-0.20.2-0.20.2-0.2-0.20.1
Na content in liver0.00.00.1-0.20.20.30.20.10.2-0.10.1-0.10.1-0.3-0.0
Rb content in liver1.92.42.51.5-1.6-1.6-1.6-1.5-1.51.5-1.51.5-1.51.61.4
Se content in liver0.10.10.2-0.40.30.30.30.40.4-0.40.4-0.40.4-0.1-0.4
Sr content in liver2.62.33.0-1.61.61.61.61.61.5-1.61.5-1.51.5-1.1-1.7
Zn content in liver3.03.33.91.8-1.9-1.9-1.9-1.8-1.81.8-1.81.7-1.71.72.0
Bone: minimum diameter0.81.42.41.1-1.0-0.9-1.0-1.2-1.21.2-1.21.4-1.41.61.3
Time in familiar zone, hab. session 11.91.82.11.3-1.4-1.4-1.4-1.4-1.31.4-1.31.2-1.21.21.4
Time in novel zone, hab. session 10.10.10.1-0.20.20.20.20.30.3-0.30.3-0.20.2-0.1-0.4
Total zone transitions, hab. session 10.10.20.2-0.40.50.50.50.50.4-0.50.4-0.40.4-0.4-0.3
Total locomotion distance, hab. session 10.30.40.5-0.70.70.70.70.70.6-0.70.6-0.60.6-0.3-0.5
Locomotion velocity, hab. session 10.71.01.3-1.01.11.11.11.11.0-1.11.0-0.90.9-0.8-0.8
Time in familiar zone, hab. session 20.20.20.30.4-0.5-0.4-0.5-0.6-0.50.6-0.50.5-0.50.20.4
Time in novel zone, hab. session 20.50.50.6-0.60.60.60.60.80.7-0.80.7-0.80.8-0.6-0.5
Total zone transitions, hab. session 21.72.22.6-1.51.51.51.51.41.5-1.41.5-1.41.4-1.4-1.6
Total locomotion distance, hab. session 22.22.93.1-1.71.81.81.71.71.7-1.71.7-1.71.7-1.7-1.7
Locomotion velocity, hab. session 21.82.42.5-1.61.61.61.61.51.5-1.51.5-1.51.5-1.5-1.6
Novel to familiar place preference ratio1.21.21.31.1-1.2-1.2-1.2-1.2-1.11.2-1.11.1-1.11.10.9
Novelty place preference1.81.81.91.3-1.4-1.4-1.4-1.4-1.41.4-1.31.3-1.31.31.2
Time in novel zone, NPP test2.12.22.31.5-1.5-1.5-1.5-1.5-1.51.5-1.51.4-1.41.41.4
Total zone transitions, NPP test1.52.22.4-1.51.51.51.51.51.5-1.51.4-1.41.4-1.5-1.6
Total locomotion distance, NPP test1.52.02.2-1.41.51.51.51.41.4-1.41.4-1.31.3-1.3-1.4
Locomotion velocity, NPP test2.13.03.3-1.71.81.81.81.71.7-1.71.7-1.61.6-1.6-1.8
Intraocular pressure0.10.10.20.2-0.3-0.3-0.3-0.2-0.30.2-0.30.2-0.2-0.10.5
Delta distance traveled before/after self-admin0.30.30.5-0.50.50.60.60.60.5-0.60.5-0.40.4-0.1-0.7
Delta ambulatory time before/after self-admin0.50.50.8-0.80.80.80.80.80.7-0.80.7-0.70.7-0.2-0.9
Parametrial fat weight0.00.10.1-0.20.30.30.30.20.3-0.20.3-0.30.3-0.3-0.4
Pavlov. Cond. lever latency1.62.03.01.3-1.5-1.5-1.5-1.5-1.41.5-1.41.2-1.21.41.7
Pavlov. Cond. magazine entry latency0.00.00.2-0.00.00.00.00.10.0-0.10.00.0-0.00.4-0.1
Pavlov. Cond. change in total contacts1.81.92.7-1.31.41.41.41.51.3-1.51.3-1.31.3-1.2-1.6
Pavlov. Cond. index score0.40.40.7-0.60.70.70.70.70.6-0.70.6-0.50.5-0.4-0.9
Pavlov. Cond. latency score0.60.71.1-0.80.90.90.90.90.8-0.90.8-0.70.7-0.6-1.1
Pavlov. Cond. lever contacts3.33.85.3-1.82.02.12.12.01.9-2.01.9-1.81.8-1.8-2.3
Pavlov. Cond. magazine entry number0.30.40.8-0.60.60.50.50.50.6-0.50.6-0.70.7-0.9-0.4
Pavlov. Cond. intertrial magazine entries2.53.03.2-1.71.71.71.71.81.7-1.81.7-1.71.7-1.8-1.6
Pavlov. Cond. lever-magazine prob. diff.0.60.81.1-0.90.90.90.90.90.9-0.90.9-0.80.8-0.6-1.1
Pavlov. Cond. response bias0.40.50.8-0.70.70.80.70.70.7-0.70.6-0.50.5-0.4-0.9
Pavlov. Cond. lever latency0.20.20.30.5-0.5-0.5-0.5-0.5-0.50.5-0.40.4-0.40.50.5
Pavlov. Cond. magazine entry latency2.12.42.8-1.51.71.71.61.61.6-1.61.6-1.51.5-1.3-1.6
Pavlov. Cond. change in total contacts0.20.30.5-0.60.70.70.60.60.5-0.60.5-0.50.5-0.7-0.3
Pavlov. Cond. index score1.21.51.7-1.21.31.31.31.31.2-1.31.2-1.21.2-1.1-1.2
Pavlov. Cond. latency score1.41.81.9-1.41.41.41.41.41.4-1.41.3-1.31.3-1.2-1.3
Pavlov. Cond. lever contacts0.00.00.0-0.20.20.20.20.20.2-0.20.1-0.10.1-0.1-0.2
Pavlov. Cond. magazine entry number0.20.30.30.5-0.6-0.6-0.6-0.6-0.50.6-0.50.5-0.50.30.6
Pavlov. Cond. intertrial magazine entries0.10.20.20.3-0.4-0.4-0.4-0.3-0.40.3-0.40.4-0.40.30.5
Pavlov. Cond. lever-magazine prob. diff.1.41.82.0-1.31.41.41.41.41.3-1.41.3-1.31.3-1.1-1.3
Pavlov. Cond. response bias0.30.40.5-0.70.70.70.70.70.7-0.70.6-0.60.6-0.6-0.6
Time in closed arm before self-admin5.96.77.02.7-2.6-2.6-2.6-2.6-2.62.6-2.62.6-2.62.32.5
Time in closed arm after self-admin1.31.31.51.1-1.1-1.0-1.1-1.2-1.11.2-1.11.2-1.21.21.2
Time in open arm before self-admin1.41.51.6-1.21.21.21.21.21.2-1.21.2-1.21.2-1.3-1.2
Time in open arm after self-admin0.50.60.8-0.80.70.70.70.80.8-0.80.8-0.80.8-0.6-0.9
Bone: periosteal estimation0.51.01.30.9-0.8-0.7-0.8-1.0-1.01.0-1.01.1-1.11.11.1
Bone: periosteal perimeter0.20.30.60.4-0.3-0.3-0.3-0.5-0.40.5-0.50.6-0.60.80.6
Bone: post-yield work0.00.00.1-0.10.10.20.10.00.0-0.00.00.1-0.1-0.1-0.2
Progressive ratio test 1 active lever presses1.41.41.71.3-1.2-1.2-1.2-1.2-1.21.2-1.21.2-1.21.11.2
Progressive ratio test 1 breakpoint1.21.21.51.2-1.1-1.1-1.1-1.2-1.11.2-1.11.0-1.01.11.1
Progressive ratio test 1 inactive lever presses1.21.31.61.2-1.0-1.0-1.1-1.2-1.11.2-1.11.1-1.11.21.2
Progressive ratio test 2 active lever presses3.43.64.12.0-1.8-1.8-1.9-2.0-1.92.0-1.91.9-1.91.81.9
Progressive ratio test 2 breakpoint3.64.14.62.1-2.0-1.9-2.0-2.1-2.02.1-2.02.0-2.01.92.0
Progressive ratio test 2 inactive lever presses4.45.16.12.2-2.2-2.2-2.2-2.2-2.22.2-2.22.3-2.32.52.2
Incentive Sensitization - Responses4.04.14.52.0-2.0-1.9-2.0-2.0-2.12.0-2.12.1-2.11.92.0
Incentive Sensitization - Breakpoint3.94.04.42.0-2.0-1.9-2.0-2.0-2.02.0-2.02.1-2.11.92.0
Sum of active levers in priming session hrs 5-60.40.30.40.6-0.6-0.6-0.6-0.6-0.60.6-0.60.6-0.60.50.4
Progressive ratio0.30.40.60.6-0.5-0.5-0.5-0.7-0.50.7-0.50.6-0.60.50.8
Food seeking constrained by brief footshock2.02.52.91.5-1.6-1.5-1.5-1.6-1.61.6-1.61.6-1.61.71.4
Seeking ratio, punishment vs. effort0.00.00.10.0-0.2-0.2-0.2-0.0-0.10.0-0.10.2-0.20.3-0.1
Retroperitoneal fat weight0.31.11.2-1.11.00.91.01.01.0-1.01.1-1.11.1-1.0-1.0
Reaction time number correct0.91.21.3-1.11.11.11.11.11.1-1.11.1-1.11.1-1.0-1.0
Reaction time mean minus median1.31.72.21.3-1.4-1.5-1.4-1.3-1.31.3-1.31.1-1.11.51.2
Reaction time mean minus median AUC2.93.74.51.9-2.1-2.1-2.1-1.9-1.91.9-1.91.8-1.82.01.8
Reaction time num false alarms0.00.00.10.1-0.2-0.2-0.2-0.1-0.20.1-0.20.2-0.20.20.2
Reaction time num false alarms AUC0.00.10.1-0.30.20.20.20.40.2-0.40.2-0.20.2-0.1-0.2
Reaction time trials correct on left0.91.21.3-1.11.11.11.11.11.1-1.11.1-1.11.1-1.0-1.0
Reaction time trials on left0.91.31.4-1.21.11.11.11.21.2-1.21.1-1.21.2-1.0-1.1
Reaction time mean0.20.30.70.5-0.6-0.6-0.6-0.5-0.60.5-0.60.6-0.60.90.5
Reaction time mean AUC0.00.00.20.1-0.2-0.2-0.2-0.1-0.20.1-0.10.1-0.10.40.1
Median of all reaction times0.00.00.1-0.10.00.10.10.10.0-0.10.00.0-0.00.3-0.1
Reaction time omissions0.00.00.1-0.10.00.00.00.10.1-0.20.1-0.10.10.4-0.2
Reaction time false alarm rate0.10.10.10.2-0.4-0.4-0.4-0.2-0.30.2-0.30.3-0.30.30.3
Reaction time premature initiation rate1.01.31.5-1.11.21.21.21.11.2-1.11.2-1.21.2-1.0-1.2
Reaction time premature initiations1.92.62.7-1.61.61.61.71.61.7-1.61.7-1.61.6-1.5-1.6
Std. dev. reaction times0.50.71.30.7-0.9-0.9-0.9-0.7-0.80.7-0.80.7-0.71.10.6
Reaction time trials completed0.91.31.4-1.21.11.11.11.21.2-1.21.1-1.21.2-1.0-1.1
Reaction time trials AUC0.60.90.9-0.90.90.90.90.90.9-0.90.9-0.90.9-0.8-0.9
Run reversals in cocaine runway, females0.70.71.10.8-0.9-0.9-0.9-0.9-0.80.9-0.80.7-0.70.91.1
Run reversals in cocaine runway, males3.43.33.91.8-2.0-2.0-1.9-1.8-1.81.8-1.81.7-1.71.81.6
Latency to leave start box in cocaine runway0.50.60.7-0.70.70.80.80.70.7-0.70.7-0.70.7-0.9-0.8
Latency to leave start box in cocaine runway, F0.10.10.2-0.20.20.20.20.20.3-0.20.3-0.30.3-0.4-0.4
Latency to leave start box in cocaine runway, M2.01.92.3-1.41.51.51.51.41.4-1.41.4-1.31.3-1.3-1.4
Std. dev. time between licks in bursts0.10.10.3-0.30.30.40.30.30.3-0.30.3-0.30.3-0.6-0.5
Total sessions with >9 infusions0.70.80.91.0-0.8-0.7-0.8-0.9-0.90.9-0.91.0-1.00.91.0
Short access day 1 total inactive lever presses0.10.10.2-0.10.40.40.40.10.4-0.10.4-0.30.30.3-0.2
Short access day 10 total inactive lever presses1.61.82.31.3-1.3-1.3-1.3-1.3-1.31.3-1.31.3-1.31.51.3
Short access day 1 total infusions2.22.32.71.6-1.5-1.5-1.5-1.6-1.51.6-1.51.5-1.51.61.6
Short access day 10 total infusions2.83.13.51.9-1.8-1.8-1.8-1.8-1.71.8-1.71.7-1.71.71.7
Short access total infusions1.61.82.01.4-1.3-1.3-1.3-1.4-1.31.4-1.31.3-1.31.31.4
Short access day 1 locomotion0.00.00.2-0.10.20.10.10.10.2-0.10.2-0.20.2-0.4-0.1
Short access day 10 total locomotion0.70.81.40.9-0.9-1.0-0.9-0.9-0.80.9-0.80.8-0.81.20.9
Short access total locomotion0.20.20.40.6-0.5-0.5-0.5-0.6-0.40.6-0.40.4-0.40.40.6
One hour access (0.3 mA shock)1.61.92.21.3-1.3-1.3-1.3-1.3-1.41.3-1.41.5-1.51.11.4
Compulsive drug intake0.90.91.30.9-0.9-0.9-0.9-0.9-1.00.9-1.01.1-1.10.71.0
One hour access (shock baseline)0.50.60.70.8-0.8-0.8-0.8-0.8-0.80.8-0.80.8-0.70.60.8
Social response proportion0.00.00.00.0-0.0-0.0-0.0-0.10.00.1-0.0-0.00.00.10.2
Social responses0.10.10.30.3-0.4-0.4-0.4-0.4-0.30.4-0.30.3-0.30.50.6
Social time0.30.40.4-0.60.60.70.70.60.6-0.60.6-0.50.5-0.6-0.6
Soleus weight0.30.80.8-0.90.90.90.90.90.9-0.90.9-0.90.9-0.9-0.9
Bone: stiffness0.61.01.31.1-1.0-0.9-1.0-1.1-1.01.1-1.11.1-1.10.90.8
Tibialis anterior weight0.00.10.2-0.30.20.20.20.40.3-0.40.3-0.40.4-0.5-0.3
Time to tail flick, vehicle, before self-admin1.61.62.4-1.21.11.11.11.31.2-1.31.2-1.31.3-1.6-1.5
Time to tail flick, vehicle, after self-admin0.00.00.10.1-0.1-0.0-0.1-0.1-0.10.1-0.10.2-0.2-0.30.1
Time to tail flick, test, before self-admin0.00.00.0-0.10.10.00.10.10.1-0.10.1-0.10.10.10.0
Time to tail flick, test, after self-admin0.30.30.60.5-0.5-0.4-0.5-0.6-0.60.6-0.60.6-0.60.70.8
Delta time to tail flick, vehicle, before/after SA1.11.11.61.0-1.0-1.0-1.0-1.1-1.01.1-1.11.1-1.11.01.3
Delta time to tail flick, test, before/after SA0.10.10.2-0.20.30.40.30.10.2-0.10.2-0.10.1-0.5-0.1
Tibia length0.30.91.21.0-0.9-0.8-0.8-1.0-1.01.0-1.01.1-1.11.00.8
Ambulatory time before self-admin5.05.25.72.4-2.3-2.3-2.3-2.3-2.32.3-2.32.4-2.41.92.0
Ambulatory time after self-admin2.22.42.71.6-1.5-1.5-1.5-1.5-1.61.5-1.61.6-1.61.61.2
Bone: tissue strength0.00.00.1-0.30.20.20.20.30.2-0.30.2-0.10.1-0.2-0.3
Total heroin consumption1.82.12.31.4-1.5-1.5-1.5-1.5-1.41.5-1.41.3-1.31.31.4
Bone: trabecular number0.30.50.7-0.80.70.70.70.70.7-0.70.7-0.70.7-0.7-0.8
Bone: trabecular spacing0.00.00.1-0.10.10.10.10.10.1-0.10.1-0.10.1-0.10.3
Bone: trabecular thickness0.91.11.41.1-1.0-1.0-1.0-1.1-1.11.1-1.11.1-1.11.21.0
Bone: trabecular tissue density0.60.81.00.9-0.8-0.8-0.8-1.0-0.91.0-0.90.9-0.90.70.9
Water consumed over 24 hours0.00.00.1-0.10.20.20.20.10.2-0.10.2-0.10.1-0.1-0.3
Number of responses in last shaping day0.20.20.30.5-0.5-0.5-0.5-0.5-0.40.5-0.40.4-0.40.30.5