Dus1l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS NM_172018.2 0.02 0.01 8.9e-03 0.01 0.01 0.01 0.01 1.6e-02 1.0e-02 6.9e-03 7.1e-03
2 Adipose alternative TSS NM_172018.2 0.02 0.01 5.7e-03 -0 0 -0 -0 4.6e-01 1.3e-01 5.4e-01 6.5e-01
3 Adipose alternative TSS XM_006247875.4 0.02 0.01 5.2e-03 0 0 0 -0 3.0e-01 1.1e-01 1.8e-01 4.4e-01
4 Adipose alternative TSS XM_006247875.4 0.02 0.01 6.1e-03 0 0 -0 0 2.6e-01 1.1e-01 4.2e-01 3.5e-01
5 Adipose alternative TSS NM_172018.2 0.02 0.01 4.6e-03 0 0 0 -0 3.1e-01 1.1e-01 2.1e-01 4.7e-01
6 Liver gene expression Dus1l 0.06 0.04 1.6e-06 0.03 0.04 0.04 0.03 2.0e-04 1.3e-05 2.9e-05 1.4e-04
7 NAcc alternative TSS XM_006247875.4 0.03 0.02 6.9e-04 0.03 0.02 0.02 0.02 6.8e-05 3.0e-04 2.8e-04 1.6e-04
8 NAcc alternative TSS NM_172018.2 0.03 0.02 7.3e-04 0.03 0.02 0.02 0.03 9.3e-06 3.7e-04 1.8e-04 8.6e-05
9 NAcc alternative TSS XM_006247875.4 0.03 0.02 6.0e-04 0.03 0.02 0.02 0.02 6.1e-05 2.9e-04 2.7e-04 1.6e-04
10 Brain gene expression Dus1l 0.07 0.05 2.9e-04 0.04 0.04 0.04 0.04 9.3e-05 9.0e-05 7.4e-05 2.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.40.7-0.7-0.40.30.3-0.3-0.80.8-0.80.80.8
Area under the delay curve1.11.72.21.31.4-1.4-1.41.41.0-1.51.5-1.5-0.0
BMI with tail0.41.45.0-1.9-1.01.00.9-0.9-1.20.4-0.40.42.2
BMI without tail1.47.512.3-3.5-2.52.32.3-2.2-3.12.8-2.82.82.7
Body weight2.19.216.1-4.0-3.43.33.3-3.3-2.62.5-2.52.52.3
Weight adjusted by age0.82.43.5-1.9-1.81.71.7-1.7-1.21.6-1.61.6-0.3
Bone surface0.30.51.2-0.6-0.60.50.5-0.5-0.51.1-1.11.10.0
Bone volume0.30.61.3-0.7-0.60.60.5-0.5-0.71.1-1.11.10.4
Breakpoint value in progressive ratio session0.50.91.9-0.5-1.21.31.3-1.30.40.1-0.10.1-1.4
Number of licking bursts0.10.20.6-0.70.1-0.1-0.10.1-0.80.5-0.50.50.6
Context. condit. distance diff. score0.91.13.6-1.4-0.0-0.1-0.20.2-1.91.0-1.01.01.2
Locomotion velocity, session 11.82.05.02.10.9-0.8-0.70.72.2-1.31.3-1.3-1.6
Locomotion distance, session 12.53.24.81.62.2-2.2-2.22.20.9-1.81.8-1.80.4
Locomotion velocity, session 24.04.87.62.82.2-2.1-2.12.12.2-2.32.3-2.3-1.1
Locomotion distance, session 20.50.71.20.41.0-1.1-1.11.1-0.1-0.70.7-0.70.9
Locomotion velocity, session 31.92.13.51.81.3-1.2-1.11.11.9-1.61.6-1.6-1.1
Locomotion distance, session 33.43.95.22.12.0-1.9-1.91.91.9-2.32.3-2.3-0.7
Stereotopy head waving bouts, day 30.50.61.31.00.5-0.5-0.50.41.2-0.90.9-0.9-0.6
Stereotopy head waving duration, day 30.40.50.70.80.6-0.6-0.60.60.8-0.80.8-0.8-0.3
Locomotion velocity, session 70.70.81.20.71.1-1.1-1.11.10.5-0.80.8-0.8-0.3
Locomotion distance, session 72.63.46.21.32.4-2.5-2.52.50.4-1.61.6-1.60.1
Stereotopy head waving bouts, day 70.20.30.3-0.5-0.60.60.6-0.6-0.30.5-0.50.50.4
Stereotopy head waving duration, day 70.20.30.4-0.6-0.60.60.6-0.6-0.40.6-0.60.60.4
Locomotion velocity, session 80.70.81.40.41.1-1.2-1.21.2-0.4-0.70.7-0.70.9
Locomotion distance, session 81.01.55.0-1.20.8-1.0-1.01.0-2.10.5-0.50.52.2
Degree of sensitization distance0.80.82.2-1.1-0.40.30.3-0.3-1.51.2-1.21.20.5
Degree of sensitization stereotypy0.40.40.6-0.8-0.60.60.6-0.5-0.70.7-0.70.70.6
Conditioned locomotion3.94.67.1-2.6-1.81.71.6-1.6-2.72.4-2.42.41.8
Cocaine response after cond. corrected0.10.20.50.5-0.10.20.2-0.20.7-0.40.4-0.4-0.4
Cocaine response after cond. not corrected0.40.61.11.00.5-0.4-0.40.41.0-1.01.0-1.0-0.4
Cocaine response before conditioning1.01.22.00.81.4-1.4-1.41.40.3-1.21.2-1.20.2
Saline control response2.43.34.6-2.2-1.71.61.6-1.6-2.02.0-2.02.01.3
Bone: connectivity density0.20.30.6-0.30.4-0.4-0.50.5-0.80.5-0.50.50.7
Bone: cortical apparent density2.03.24.12.01.9-1.9-1.81.81.8-1.81.8-1.8-0.9
Bone: cortical area3.96.39.8-2.9-3.13.13.1-3.1-1.61.7-1.71.72.2
Bone: cortical porosity1.11.22.6-0.1-1.41.61.6-1.61.00.2-0.20.2-1.2
Bone: cortical porosity1.41.53.3-0.5-1.71.81.8-1.80.60.6-0.60.6-0.9
Bone: cortical thickness3.55.810.9-2.5-3.23.33.3-3.3-0.91.2-1.21.21.9
Bone: cortical thickness0.91.12.2-1.1-1.41.51.5-1.5-0.30.2-0.20.21.0
Bone: cortical tissue density2.23.54.52.12.0-1.9-1.91.91.9-1.91.9-1.9-1.0
Condit. Reinf. active minus inactive responses2.22.53.3-1.8-1.71.61.6-1.6-1.61.6-1.61.61.2
Condit. Reinf. active-inactive response ratio0.80.91.4-1.2-1.01.01.0-1.0-0.90.7-0.70.70.9
Condit. Reinf. active responses4.25.46.6-2.6-2.32.22.1-2.1-2.42.6-2.62.61.7
Condit. Reinf. inactive responses1.31.72.8-1.2-1.11.11.1-1.1-1.31.7-1.71.70.6
Incentive salience index mean1.72.23.1-1.8-1.41.31.3-1.3-1.61.6-1.61.61.3
Condit. Reinf. lever presses0.10.20.7-0.50.2-0.3-0.30.3-0.70.3-0.30.30.8
Condit. Reinf. active minus inactive responses0.30.50.7-0.8-0.80.70.7-0.7-0.90.6-0.60.60.8
Condit. Reinf. active-inactive response ratio1.32.03.2-1.2-1.81.81.8-1.8-0.81.3-1.31.30.3
Condit. Reinf. active responses0.10.10.4-0.3-0.20.10.1-0.1-0.60.2-0.20.20.7
Condit. Reinf. inactive responses0.60.81.30.71.1-1.1-1.21.20.3-0.90.9-0.90.1
Condit. Reinf. lever presses0.20.31.0-0.7-0.20.10.1-0.1-1.00.6-0.60.60.7
Condit. Reinf. lever reinforcers received0.10.20.7-0.4-0.10.00.0-0.0-0.80.3-0.30.30.8
Conditioned reinforcement - actives0.00.20.30.20.5-0.6-0.60.6-0.0-0.40.4-0.40.3
Conditioned reinforcement - inactives0.10.30.5-0.5-0.60.60.6-0.6-0.50.6-0.60.60.7
Conditioned locomotion0.10.10.9-0.30.2-0.2-0.30.3-0.20.1-0.10.11.0
Patch foraging indifference point 0 sec0.10.20.3-0.4-0.30.30.3-0.3-0.30.5-0.50.50.3
Patch foraging indifference point AUC0.00.10.2-0.1-0.10.00.0-0.0-0.50.5-0.50.50.2
Delay disc. indifference point, 0s delay0.10.10.1-0.20.1-0.2-0.10.20.0-0.30.3-0.3-0.3
Delay disc. indifference point, 16s delay1.31.83.40.81.7-1.8-1.81.80.1-1.11.1-1.11.0
Delay disc. indifference point, 2s delay0.40.50.70.70.6-0.5-0.50.50.8-0.80.8-0.8-0.4
Delay disc. indifference point, 24s delay3.04.77.22.72.1-2.0-1.91.92.5-2.42.4-2.4-0.7
Delay disc. indifference point, 4s delay0.40.40.70.60.5-0.4-0.40.40.5-0.80.8-0.8-0.8
Delay disc. indifference point, 8s delay0.50.91.61.30.7-0.6-0.60.61.2-1.21.2-1.2-0.3
Indifference point function ln k0.51.52.40.91.2-1.2-1.21.20.8-1.61.6-1.60.1
Indifference point function log k0.51.52.40.91.2-1.2-1.21.20.8-1.61.6-1.60.1
Patch foraging total patch changes 0 sec0.10.20.3-0.4-0.30.30.3-0.3-0.40.5-0.50.50.5
Patch foraging total patch changes 12 sec0.30.30.6-0.1-0.50.50.5-0.5-0.10.8-0.80.8-0.7
Patch foraging total patch changes 18 sec0.10.10.3-0.10.4-0.4-0.40.4-0.60.3-0.30.30.3
Patch foraging total patch changes 24 sec0.30.91.4-1.2-0.90.90.9-0.9-0.91.0-1.01.00.8
Patch foraging total patch changes 6 sec0.40.61.0-0.5-0.90.90.9-0.9-0.31.0-1.01.00.1
Patch foraging time to switch 0 sec0.10.50.70.80.9-0.8-0.80.80.8-0.60.6-0.6-0.6
Patch foraging water rate 0 sec0.72.74.5-2.1-1.71.61.6-1.6-1.91.5-1.51.51.1
Patch foraging water rate 12 sec0.10.41.8-0.9-0.20.20.1-0.1-1.10.2-0.20.21.3
Patch foraging water rate 18 sec0.40.82.8-1.4-0.40.30.3-0.3-1.40.6-0.60.61.7
Patch foraging water rate 24 sec1.72.45.3-2.3-1.10.90.9-0.9-2.31.4-1.41.42.2
Patch foraging water rate 6 sec0.10.10.5-0.6-0.1-0.0-0.00.0-0.5-0.30.3-0.30.7
Seeking ratio, delayed vs. immediate footshock0.91.31.8-1.4-1.21.21.1-1.1-1.31.2-1.21.20.3
Distance traveled before self-admin0.51.12.0-0.9-1.41.41.4-1.4-0.30.7-0.70.7-0.8
Distance traveled after self-admin0.50.91.7-1.2-0.70.60.6-0.6-1.31.2-1.21.20.2
Extensor digitorum longus weight0.20.72.6-1.00.2-0.3-0.30.3-1.50.6-0.60.61.6
Bone: elastic displacement1.01.32.0-1.1-1.41.41.4-1.4-0.51.0-1.01.00.5
Bone: elastic work6.07.814.8-2.4-3.73.83.8-3.8-0.82.2-2.22.20.4
Bone: endosteal estimation0.10.20.6-0.30.5-0.5-0.60.6-0.80.3-0.30.30.3
Bone: endosteal perimeter0.51.21.5-1.2-1.11.11.1-1.1-0.91.2-1.21.20.2
Epididymis fat weight0.73.57.2-2.7-1.71.51.5-1.5-2.31.7-1.71.72.1
Delta time in closed arm before/after self-admin0.40.40.7-0.20.7-0.8-0.80.8-0.7-0.10.1-0.10.7
Delta time in open arm before/after self-admin0.00.00.10.10.2-0.1-0.10.10.2-0.20.2-0.20.0
Diff in mean of infusions in LGA sessions0.20.42.5-0.2-0.50.50.5-0.50.10.0-0.00.0-1.6
Delay discount exponential model param1.82.43.3-1.7-1.51.51.5-1.5-1.41.8-1.81.80.4
Extinction: sum of active levers before priming0.50.71.50.90.6-0.5-0.50.51.2-1.11.1-1.1-0.2
Active lever presses in extinction session 61.51.54.61.1-0.10.30.3-0.32.1-1.51.5-1.5-1.3
Bone: final force4.47.210.5-3.2-3.23.23.2-3.2-2.12.0-2.02.02.2
Bone: final moment5.38.512.7-3.4-3.63.53.5-3.5-2.02.2-2.22.22.0
Food consumed during 24 hour testing period0.30.61.0-0.9-0.60.60.6-0.6-0.81.0-1.01.00.2
Glucose6.911.025.64.31.6-1.2-1.11.15.1-3.63.6-3.6-4.4
Heart weight0.61.02.1-0.9-1.41.41.4-1.4-0.20.7-0.70.70.1
Delay discount hyperbolic model param1.72.12.9-1.6-1.41.41.4-1.4-1.41.7-1.71.70.5
Intermittent access intake day 1-15 change0.21.01.6-0.3-1.21.31.3-1.3-0.21.1-1.11.1-0.6
Intermittent access intake escalation0.20.91.4-0.3-1.11.21.2-1.2-0.21.0-1.01.0-0.4
Intermittent access intake escalation 21.22.13.7-0.8-1.81.91.9-1.9-0.11.1-1.11.1-1.5
Intermitt. access day 1 inactive lever presses0.33.56.8-1.8-1.61.51.4-1.4-2.12.0-2.02.02.6
Intermitt. access day 15 inactive lever presses0.21.12.8-1.1-0.50.50.4-0.4-1.41.2-1.21.21.7
Intermitt. access escalation Index0.20.61.4-0.8-0.30.20.2-0.2-1.20.9-0.90.91.0
Intermittent access day 1 total infusions0.00.10.4-0.1-0.20.20.2-0.2-0.20.3-0.30.30.6
Intermittent access day 15 total infusions0.30.71.1-0.5-0.80.80.8-0.8-0.61.0-1.01.00.4
Intermittent access terminal intake (last 3 days)0.61.01.5-0.7-1.11.11.1-1.1-0.61.2-1.21.2-0.3
Intermittent access total infusions0.20.30.4-0.3-0.50.50.5-0.5-0.40.6-0.60.60.5
Intermittent access day 1 locomotion0.10.10.9-0.20.2-0.2-0.20.2-0.1-0.30.3-0.30.9
Intermittent access day 15 total locomotion0.20.60.8-0.6-0.80.80.8-0.8-0.40.9-0.90.90.7
Intermittent access total locomotion0.20.20.8-0.4-0.40.40.4-0.4-0.30.4-0.40.40.9
Intermittent access standard deviation0.10.72.31.1-0.10.20.2-0.21.5-0.90.9-0.9-0.9
Left kidney weight0.00.20.3-0.1-0.50.50.6-0.60.6-0.20.2-0.20.3
Right kidney weight0.00.20.7-0.1-0.20.30.3-0.30.6-0.50.5-0.50.8
Cocaine induced anxiety0.61.63.8-0.2-1.81.92.0-2.01.0-0.40.4-0.4-0.7
Post-drug Anxiety0.91.02.70.9-0.80.91.0-1.01.6-0.90.9-0.9-0.7
Baseline Anxiety0.71.22.11.51.4-1.3-1.31.30.9-0.60.6-0.6-0.5
Tail length2.312.215.4-3.9-3.63.53.5-3.5-3.33.9-3.93.91.1
Length with tail1.46.010.0-2.6-3.13.13.2-3.2-1.22.0-2.02.0-0.0
Length without tail0.31.42.7-0.3-1.41.61.6-1.61.3-0.60.6-0.6-1.1
Times rat made contact with spout2.12.44.3-0.6-1.51.61.6-1.6-0.12.1-2.12.1-1.2
Lifetime Intake0.00.00.30.1-0.10.10.1-0.1-0.10.2-0.20.20.6
Liver weight, left0.81.32.41.20.9-0.8-0.80.71.4-1.51.5-1.5-0.5
Liver weight, right1.73.06.3-2.5-1.61.61.5-1.5-1.91.6-1.61.61.6
Locomotor activity0.61.01.11.11.0-1.0-1.01.01.0-1.01.0-1.0-0.8
Locomotor testing distance1.02.43.41.11.8-1.8-1.81.80.9-1.71.7-1.7-0.4
Locomotor testing rearing0.20.71.40.51.1-1.2-1.21.20.1-0.50.5-0.5-0.3
Locomotion in novel chamber0.40.50.80.10.8-0.9-0.90.90.0-0.60.6-0.60.9
Locomotion in novel chamber post-restriction1.54.66.1-2.0-2.32.22.2-2.2-1.92.5-2.52.50.9
Fecal boli incidents, locomotor time 10.10.40.80.40.9-0.9-0.90.90.2-0.30.3-0.30.4
Change in fecal boli incidents, locomotor task1.92.06.22.00.5-0.4-0.40.32.0-1.31.3-1.3-2.5
Time >=10cm from walls, locomotor time 11.01.32.8-1.1-0.40.20.2-0.2-1.71.4-1.41.41.5
Bouts of movement, locomotor time 11.21.62.11.41.2-1.2-1.11.11.4-1.51.5-1.5-0.6
Total resting periods, locomotor time 11.72.02.91.71.3-1.2-1.21.21.6-1.61.6-1.6-1.0
Rest time, locomotor task time 10.40.61.51.10.3-0.2-0.20.21.2-0.80.8-0.8-1.1
Distance moved, locomotor task time 10.10.41.0-1.0-0.50.40.4-0.4-0.90.6-0.60.60.1
Vertical activity count, locomotor time 10.11.02.6-1.6-0.70.60.5-0.5-1.50.9-0.90.90.9
Time >=10cm from walls, locomotor time 20.00.10.2-0.1-0.20.20.2-0.2-0.20.5-0.50.50.2
Bouts of movement, locomotor time 20.41.21.71.01.2-1.2-1.21.20.7-1.31.3-1.30.5
Total resting periods, locomotor time 20.20.91.30.61.1-1.1-1.11.10.2-0.90.9-0.90.9
Rest time, locomotor task time 20.00.10.10.20.2-0.2-0.20.20.0-0.30.3-0.3-0.3
Distance moved, locomotor task time 20.00.00.2-0.2-0.0-0.0-0.00.00.0-0.00.0-0.0-0.4
Vertical activity count, locomotor time 20.00.10.3-0.40.2-0.2-0.20.2-0.50.0-0.00.00.6
Light reinforcement 10.42.04.8-2.2-0.70.60.5-0.5-2.21.4-1.41.41.7
Light reinforcement 21.12.45.5-2.3-1.31.21.2-1.2-2.01.4-1.41.41.6
Bone: marrow area0.10.20.6-0.20.5-0.5-0.60.6-0.80.3-0.30.30.3
Bone: maximum diameter0.81.72.6-1.6-1.61.61.6-1.6-0.90.8-0.80.81.2
Bone: maximum force3.87.610.7-3.3-3.33.23.2-3.1-2.32.2-2.22.22.2
Bone: maximum moment4.58.612.6-3.4-3.53.53.5-3.5-2.22.4-2.42.42.0
Mean time between licks in bursts0.32.12.51.51.6-1.6-1.61.61.1-1.61.6-1.6-0.3
Mean num. licks in bursts0.30.71.20.1-0.91.01.0-1.00.40.8-0.80.8-1.1
Cd content in liver0.40.51.10.31.0-1.0-1.11.1-0.4-0.30.3-0.30.4
Co content in liver0.00.10.2-0.2-0.10.10.1-0.1-0.00.4-0.40.40.1
Cu content in liver0.81.01.9-0.7-1.31.31.4-1.40.00.8-0.80.8-0.3
Fe content in liver0.50.61.00.41.0-1.0-1.01.00.2-0.80.8-0.80.1
K content in liver1.61.53.9-1.7-0.40.30.3-0.3-2.01.3-1.31.31.7
Mg content in liver1.21.33.8-1.20.4-0.5-0.60.6-2.01.1-1.11.11.7
Mn content in liver0.00.00.2-0.3-0.20.10.1-0.1-0.30.1-0.10.10.5
Na content in liver0.10.20.4-0.30.4-0.5-0.50.5-0.5-0.10.1-0.10.6
Rb content in liver2.02.34.6-1.9-1.00.90.8-0.8-2.11.7-1.71.71.6
Se content in liver0.40.50.9-0.8-0.40.40.4-0.4-0.80.9-0.90.90.5
Sr content in liver0.50.41.50.8-0.20.30.3-0.31.2-0.50.5-0.5-1.1
Zn content in liver1.61.83.0-1.4-1.11.01.0-1.0-1.51.7-1.71.70.8
Bone: minimum diameter2.54.76.5-2.5-2.62.52.5-2.5-1.51.9-1.91.91.4
Time in familiar zone, hab. session 10.10.10.20.4-0.20.30.3-0.30.4-0.00.0-0.0-0.4
Time in novel zone, hab. session 10.00.00.1-0.20.2-0.2-0.20.2-0.30.0-0.00.00.2
Total zone transitions, hab. session 10.30.40.50.40.7-0.7-0.70.70.2-0.70.7-0.70.1
Total locomotion distance, hab. session 10.10.21.0-0.60.1-0.1-0.10.1-0.60.1-0.10.11.0
Locomotion velocity, hab. session 10.20.21.2-0.70.1-0.1-0.10.1-0.70.1-0.10.11.1
Time in familiar zone, hab. session 20.20.20.40.40.6-0.6-0.60.60.2-0.30.3-0.3-0.0
Time in novel zone, hab. session 20.00.10.10.10.1-0.1-0.10.10.1-0.40.4-0.40.1
Total zone transitions, hab. session 20.60.71.8-0.20.9-1.0-1.11.1-1.0-0.10.1-0.11.4
Total locomotion distance, hab. session 20.81.14.1-1.20.1-0.3-0.30.3-1.80.7-0.70.72.0
Locomotion velocity, hab. session 21.01.34.4-1.5-0.2-0.0-0.10.1-2.00.9-0.90.92.1
Novel to familiar place preference ratio2.02.64.8-1.3-2.12.22.2-2.2-0.51.3-1.31.3-0.1
Novelty place preference2.02.54.7-1.2-2.12.22.2-2.2-0.41.3-1.31.3-0.2
Time in novel zone, NPP test1.72.03.7-1.2-1.91.91.9-1.9-0.41.1-1.11.1-0.1
Total zone transitions, NPP test0.91.32.5-0.11.4-1.5-1.61.6-1.1-0.30.3-0.31.6
Total locomotion distance, NPP test0.91.34.9-1.00.7-0.9-0.91.0-1.80.4-0.40.42.2
Locomotion velocity, NPP test0.71.04.0-1.10.4-0.5-0.60.6-1.70.6-0.60.62.0
Intraocular pressure0.81.31.9-1.3-1.00.90.9-0.9-1.41.3-1.31.30.7
Delta distance traveled before/after self-admin0.30.30.70.10.8-0.8-0.80.8-0.4-0.10.1-0.10.3
Delta ambulatory time before/after self-admin0.61.02.30.61.4-1.5-1.51.5-0.1-0.50.5-0.50.2
Parametrial fat weight0.71.62.7-1.6-0.90.80.8-0.8-1.51.5-1.51.51.5
Pavlov. Cond. lever latency0.91.22.50.51.5-1.5-1.61.6-0.4-0.60.6-0.60.8
Pavlov. Cond. magazine entry latency2.12.75.1-1.1-2.22.22.3-2.3-0.21.3-1.31.3-0.5
Pavlov. Cond. change in total contacts0.50.61.20.1-0.91.11.1-1.10.90.1-0.10.1-0.7
Pavlov. Cond. index score2.73.45.7-1.6-2.32.42.4-2.4-0.71.6-1.61.6-0.0
Pavlov. Cond. latency score2.12.74.9-1.3-2.12.22.2-2.2-0.31.4-1.41.4-0.4
Pavlov. Cond. lever contacts0.60.71.4-0.7-1.11.21.2-1.2-0.10.6-0.60.6-0.3
Pavlov. Cond. magazine entry number2.43.06.20.92.4-2.5-2.52.5-0.3-1.21.2-1.21.0
Pavlov. Cond. intertrial magazine entries0.50.61.6-0.8-0.10.00.0-0.0-1.30.8-0.80.81.2
Pavlov. Cond. lever-magazine prob. diff.2.53.25.4-1.6-2.32.32.3-2.3-0.61.6-1.61.60.0
Pavlov. Cond. response bias1.72.14.5-0.8-2.02.12.1-2.10.21.0-1.01.0-0.8
Pavlov. Cond. lever latency0.91.33.01.40.6-0.5-0.40.41.7-1.41.4-1.4-0.9
Pavlov. Cond. magazine entry latency1.31.83.51.01.8-1.9-1.91.90.2-1.01.0-1.0-0.0
Pavlov. Cond. change in total contacts0.10.20.5-0.00.7-0.7-0.70.7-0.4-0.00.0-0.00.3
Pavlov. Cond. index score0.10.20.4-0.10.6-0.6-0.60.7-0.50.1-0.10.10.2
Pavlov. Cond. latency score0.20.30.5-0.20.6-0.7-0.70.7-0.60.2-0.20.20.4
Pavlov. Cond. lever contacts0.71.02.6-1.3-0.40.30.3-0.3-1.61.3-1.31.30.8
Pavlov. Cond. magazine entry number0.91.22.4-0.7-1.51.51.5-1.5-0.10.9-0.90.9-0.1
Pavlov. Cond. intertrial magazine entries0.92.02.5-1.6-1.41.41.3-1.3-1.51.5-1.51.51.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.20.8-0.8-0.90.9-0.3-0.10.1-0.10.1
Pavlov. Cond. response bias0.10.20.7-0.40.3-0.3-0.40.4-0.80.3-0.30.30.3
Time in closed arm before self-admin0.30.41.30.90.00.10.1-0.11.2-0.80.8-0.8-0.6
Time in closed arm after self-admin0.80.91.61.30.5-0.4-0.40.41.2-1.21.2-1.2-0.9
Time in open arm before self-admin0.30.40.9-0.70.4-0.5-0.50.5-0.90.6-0.60.60.7
Time in open arm after self-admin0.10.20.6-0.40.3-0.4-0.40.4-0.50.2-0.20.20.8
Bone: periosteal estimation1.02.53.9-2.0-1.81.71.7-1.7-1.41.3-1.31.31.4
Bone: periosteal perimeter2.34.58.6-1.9-2.82.92.9-2.9-0.61.6-1.61.60.2
Bone: post-yield work0.00.10.10.00.3-0.3-0.30.3-0.3-0.10.1-0.10.2
Progressive ratio test 1 active lever presses0.20.30.5-0.5-0.50.50.5-0.5-0.60.7-0.70.70.7
Progressive ratio test 1 breakpoint0.20.40.6-0.6-0.60.60.6-0.6-0.60.8-0.80.80.7
Progressive ratio test 1 inactive lever presses1.33.55.1-2.1-1.51.41.4-1.4-2.32.1-2.12.12.1
Progressive ratio test 2 active lever presses0.20.40.7-0.5-0.50.40.4-0.4-0.60.7-0.70.70.8
Progressive ratio test 2 breakpoint0.30.40.6-0.5-0.50.50.5-0.5-0.60.7-0.70.70.8
Progressive ratio test 2 inactive lever presses0.10.30.5-0.2-0.70.70.7-0.7-0.20.5-0.50.50.2
Incentive Sensitization - Responses0.20.40.7-0.5-0.50.50.4-0.4-0.70.8-0.80.80.6
Incentive Sensitization - Breakpoint0.20.30.6-0.4-0.50.40.4-0.4-0.60.8-0.80.80.5
Sum of active levers in priming session hrs 5-60.90.91.6-0.6-1.21.31.3-1.30.40.4-0.40.4-1.2
Progressive ratio0.31.01.41.21.1-1.0-1.01.01.0-1.11.1-1.1-0.3
Food seeking constrained by brief footshock0.20.21.00.7-0.00.10.1-0.11.0-0.30.3-0.3-0.6
Seeking ratio, punishment vs. effort0.10.30.7-0.5-0.30.30.3-0.3-0.60.6-0.60.60.8
Retroperitoneal fat weight2.712.020.9-4.6-3.12.92.8-2.8-3.93.6-3.63.63.3
Reaction time number correct0.51.85.5-1.30.9-1.1-1.21.2-2.40.3-0.30.32.3
Reaction time mean minus median0.00.31.10.60.10.00.0-0.00.9-0.30.3-0.3-1.1
Reaction time mean minus median AUC0.00.00.30.1-0.00.00.0-0.00.3-0.20.2-0.2-0.5
Reaction time num false alarms0.10.10.40.60.5-0.4-0.40.40.5-0.10.1-0.1-0.1
Reaction time num false alarms AUC0.20.50.80.80.9-0.9-0.90.90.6-0.50.5-0.50.0
Reaction time trials correct on left0.51.85.5-1.30.9-1.1-1.21.2-2.40.3-0.30.32.3
Reaction time trials on left0.51.85.7-1.30.9-1.1-1.21.2-2.40.3-0.30.32.3
Reaction time mean0.10.30.5-0.7-0.50.40.4-0.4-0.60.6-0.60.60.1
Reaction time mean AUC0.10.30.7-0.8-0.20.10.1-0.1-0.80.5-0.50.50.5
Median of all reaction times0.30.40.9-0.9-0.50.40.4-0.4-0.90.7-0.70.70.5
Reaction time omissions0.10.10.3-0.6-0.00.0-0.0-0.0-0.50.4-0.40.40.3
Reaction time false alarm rate0.50.72.81.40.3-0.2-0.20.21.7-0.50.5-0.5-1.2
Reaction time premature initiation rate0.91.42.21.51.3-1.2-1.21.21.1-1.21.2-1.2-0.3
Reaction time premature initiations0.41.42.70.51.5-1.6-1.61.7-0.3-0.80.8-0.81.0
Std. dev. reaction times0.10.30.40.60.6-0.6-0.60.60.5-0.40.4-0.4-0.6
Reaction time trials completed0.51.85.7-1.30.9-1.1-1.21.2-2.40.3-0.30.32.3
Reaction time trials AUC0.51.85.8-1.40.9-1.1-1.21.2-2.40.4-0.40.42.3
Run reversals in cocaine runway, females0.50.61.10.71.0-1.0-1.11.1-0.1-0.40.4-0.41.0
Run reversals in cocaine runway, males1.41.62.7-1.0-1.61.61.7-1.7-0.21.0-1.01.0-0.8
Latency to leave start box in cocaine runway0.30.30.70.60.8-0.8-0.80.80.1-0.40.4-0.4-0.1
Latency to leave start box in cocaine runway, F0.60.71.60.01.1-1.2-1.31.3-0.70.0-0.00.00.9
Latency to leave start box in cocaine runway, M0.20.20.80.6-0.20.30.3-0.30.6-0.30.3-0.3-0.9
Std. dev. time between licks in bursts0.71.34.6-1.40.3-0.5-0.60.6-2.10.6-0.60.62.1
Total sessions with >9 infusions0.30.40.60.80.7-0.7-0.70.70.6-0.60.6-0.60.2
Short access day 1 total inactive lever presses0.20.31.8-0.40.5-0.5-0.50.6-0.4-0.10.1-0.11.3
Short access day 10 total inactive lever presses0.53.44.6-2.1-1.81.71.7-1.7-2.12.0-2.02.01.2
Short access day 1 total infusions0.91.82.31.51.5-1.5-1.51.51.2-1.41.4-1.40.0
Short access day 10 total infusions0.71.21.7-0.8-1.21.21.2-1.2-0.61.3-1.31.30.4
Short access total infusions0.00.10.10.40.2-0.2-0.20.20.3-0.20.2-0.20.3
Short access day 1 locomotion0.20.41.00.90.3-0.2-0.20.21.0-0.70.7-0.7-0.4
Short access day 10 total locomotion0.10.51.60.7-0.20.30.4-0.41.2-0.60.6-0.6-1.3
Short access total locomotion0.10.20.80.5-0.20.30.3-0.30.9-0.40.4-0.4-0.4
One hour access (0.3 mA shock)0.40.51.0-0.6-0.40.40.3-0.3-0.80.8-0.80.81.0
Compulsive drug intake0.60.92.2-1.4-0.40.30.2-0.2-1.50.8-0.80.81.5
One hour access (shock baseline)0.00.10.2-0.0-0.0-0.0-0.00.0-0.20.4-0.40.40.2
Social response proportion0.30.40.60.40.8-0.8-0.80.80.1-0.60.6-0.60.1
Social responses0.30.40.50.10.7-0.7-0.70.70.1-0.70.7-0.70.6
Social time0.10.20.30.00.5-0.5-0.50.50.0-0.60.6-0.60.5
Soleus weight1.23.74.6-2.1-2.01.91.9-1.9-1.82.1-2.12.10.9
Bone: stiffness0.40.72.1-1.1-0.90.80.8-0.8-0.80.0-0.00.01.4
Tibialis anterior weight0.00.10.4-0.30.1-0.2-0.20.2-0.70.4-0.40.40.6
Time to tail flick, vehicle, before self-admin0.10.10.20.50.5-0.5-0.50.50.3-0.10.1-0.10.2
Time to tail flick, vehicle, after self-admin1.32.63.51.31.8-1.7-1.71.71.2-1.91.9-1.90.1
Time to tail flick, test, before self-admin0.10.10.70.90.2-0.2-0.20.20.4-0.20.2-0.20.1
Time to tail flick, test, after self-admin1.11.22.11.30.8-0.7-0.70.71.4-1.41.4-1.4-0.8
Delta time to tail flick, vehicle, before/after SA0.20.20.3-0.20.5-0.5-0.60.6-0.3-0.40.4-0.40.4
Delta time to tail flick, test, before/after SA0.60.71.50.70.3-0.3-0.20.21.2-1.11.1-1.1-1.2
Tibia length7.621.033.9-4.8-5.85.85.8-5.8-2.63.8-3.83.81.6
Ambulatory time before self-admin0.82.54.1-1.6-2.02.02.0-2.0-0.81.3-1.31.3-0.1
Ambulatory time after self-admin0.40.60.9-0.9-0.60.50.5-0.5-0.91.0-1.01.00.3
Bone: tissue strength1.71.83.2-1.8-1.21.11.1-1.1-1.61.2-1.21.21.6
Total heroin consumption0.50.61.10.2-0.40.50.6-0.61.1-1.01.0-1.0-0.8
Bone: trabecular number0.00.10.2-0.0-0.20.20.2-0.2-0.10.5-0.50.5-0.1
Bone: trabecular spacing0.71.03.7-1.20.5-0.6-0.70.7-1.80.3-0.30.31.9
Bone: trabecular thickness1.01.42.5-0.1-1.41.61.6-1.60.60.9-0.90.9-1.2
Bone: trabecular tissue density0.61.11.51.11.2-1.2-1.21.20.8-1.11.1-1.1-0.4
Water consumed over 24 hours0.10.31.40.5-0.20.30.3-0.30.80.2-0.20.2-1.2
Number of responses in last shaping day0.20.20.40.10.3-0.3-0.30.30.3-0.60.6-0.60.6