Dus1l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS NM_172018.2 0.02 0.01 5.7e-03 -0 0 -0 -0 4.6e-01 1.3e-01 5.4e-01 6.5e-01
2 Adipose alternative TSS XM_006247875.4 0.02 0.01 5.2e-03 0 0 0 -0 3.0e-01 1.1e-01 1.8e-01 4.5e-01
3 Adipose alternative TSS XM_006247875.4 0.02 0.01 6.1e-03 0 0 -0 0 2.6e-01 1.1e-01 4.2e-01 3.6e-01
4 Adipose alternative TSS NM_172018.2 0.02 0.01 4.6e-03 0 0 0 -0 3.1e-01 1.1e-01 2.1e-01 5.1e-01
5 Liver gene expression Dus1l 0.06 0.04 1.6e-06 0.03 0.04 0.04 0.03 2.0e-04 1.3e-05 2.9e-05 1.1e-04
6 NAcc alternative TSS XM_006247875.4 0.03 0.02 6.9e-04 0.03 0.02 0.02 0.02 6.8e-05 3.0e-04 2.8e-04 1.5e-04
7 NAcc alternative TSS NM_172018.2 0.03 0.02 7.3e-04 0.03 0.02 0.02 0.03 9.3e-06 3.7e-04 1.8e-04 8.8e-05
8 NAcc alternative TSS XM_006247875.4 0.03 0.02 6.0e-04 0.03 0.02 0.02 0.02 6.1e-05 2.9e-04 2.7e-04 1.6e-04
9 Brain gene expression Dus1l 0.07 0.05 2.9e-04 0.04 0.04 0.04 0.04 9.3e-05 9.0e-05 7.4e-05 2.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.40.7-0.40.30.3-0.3-0.8-0.80.8-0.8-0.8
Area under the delay curve1.51.72.21.4-1.4-1.41.41.01.5-1.51.50.0
BMI with tail0.31.25.0-1.01.00.9-0.9-1.2-0.40.4-0.4-2.2
BMI without tail2.36.99.8-2.52.32.3-2.2-3.1-2.82.8-2.8-2.7
Body weight1.98.511.7-3.43.33.3-3.3-2.6-2.52.5-2.5-2.3
Weight adjusted by age1.52.33.1-1.81.71.7-1.7-1.2-1.61.6-1.60.3
Bone surface0.30.51.2-0.60.50.5-0.5-0.5-1.11.1-1.1-0.0
Bone volume0.40.61.3-0.60.60.5-0.5-0.7-1.11.1-1.1-0.4
Breakpoint value in progressive ratio session0.81.01.9-1.21.31.3-1.30.4-0.10.1-0.11.4
Number of licking bursts0.10.20.60.1-0.1-0.10.1-0.8-0.50.5-0.5-0.6
Context. condit. distance diff. score0.80.93.6-0.0-0.1-0.20.2-1.9-1.01.0-1.0-1.2
Locomotion velocity, session 11.61.75.00.9-0.8-0.70.72.21.3-1.31.31.6
Locomotion distance, session 12.63.34.82.2-2.2-2.22.20.91.8-1.81.8-0.4
Locomotion velocity, session 23.84.55.42.2-2.1-2.12.12.22.3-2.32.31.1
Locomotion distance, session 20.50.71.21.0-1.1-1.11.1-0.10.7-0.70.7-0.9
Locomotion velocity, session 31.82.03.51.3-1.2-1.11.11.91.6-1.61.61.1
Locomotion distance, session 33.53.85.22.0-1.9-1.91.91.92.3-2.32.30.7
Stereotopy head waving bouts, day 30.50.61.30.5-0.5-0.50.41.20.9-0.90.90.6
Stereotopy head waving duration, day 30.40.50.70.6-0.6-0.60.60.80.8-0.80.80.3
Locomotion velocity, session 70.70.81.21.1-1.1-1.11.10.50.8-0.80.80.3
Locomotion distance, session 72.83.66.22.4-2.5-2.52.50.41.6-1.61.6-0.1
Stereotopy head waving bouts, day 70.20.30.3-0.60.60.6-0.6-0.3-0.50.5-0.5-0.4
Stereotopy head waving duration, day 70.20.30.3-0.60.60.6-0.6-0.4-0.60.6-0.6-0.4
Locomotion velocity, session 80.70.91.41.1-1.2-1.21.2-0.40.7-0.70.7-0.9
Locomotion distance, session 81.01.55.00.8-1.0-1.01.0-2.1-0.50.5-0.5-2.2
Degree of sensitization distance0.80.82.2-0.40.30.3-0.3-1.5-1.21.2-1.2-0.5
Degree of sensitization stereotypy0.30.40.4-0.60.60.6-0.5-0.7-0.70.7-0.7-0.6
Conditioned locomotion3.84.37.1-1.81.71.6-1.6-2.7-2.42.4-2.4-1.8
Cocaine response after cond. corrected0.10.10.5-0.10.20.2-0.20.70.4-0.40.40.4
Cocaine response after cond. not corrected0.50.61.10.5-0.4-0.40.41.01.0-1.01.00.4
Cocaine response before conditioning1.11.32.01.4-1.4-1.41.40.31.2-1.21.2-0.2
Saline control response2.33.14.1-1.71.61.6-1.6-2.0-2.02.0-2.0-1.3
Bone: connectivity density0.20.30.60.4-0.4-0.50.5-0.8-0.50.5-0.5-0.7
Bone: cortical apparent density2.33.13.71.9-1.9-1.81.81.81.8-1.81.80.9
Bone: cortical area4.06.19.8-3.13.13.1-3.1-1.6-1.71.7-1.7-2.2
Bone: cortical porosity1.31.42.6-1.41.61.6-1.61.0-0.20.2-0.21.2
Bone: cortical porosity1.51.73.3-1.71.81.8-1.80.6-0.60.6-0.60.9
Bone: cortical thickness3.55.710.9-3.23.33.3-3.3-0.9-1.21.2-1.2-1.9
Bone: cortical thickness0.91.12.2-1.41.51.5-1.5-0.3-0.20.2-0.2-1.0
Bone: cortical tissue density2.53.44.02.0-1.9-1.91.91.91.9-1.91.91.0
Condit. Reinf. active minus inactive responses2.22.52.7-1.71.61.6-1.6-1.6-1.61.6-1.6-1.2
Condit. Reinf. active-inactive response ratio0.70.81.1-1.01.01.0-1.0-0.9-0.70.7-0.7-0.9
Condit. Reinf. active responses4.25.26.6-2.32.22.1-2.1-2.4-2.62.6-2.6-1.7
Condit. Reinf. inactive responses1.41.72.8-1.11.11.1-1.1-1.3-1.71.7-1.7-0.6
Incentive salience index mean1.72.12.6-1.41.31.3-1.3-1.6-1.61.6-1.6-1.3
Condit. Reinf. lever presses0.10.20.70.2-0.3-0.30.3-0.7-0.30.3-0.3-0.8
Condit. Reinf. active minus inactive responses0.40.50.7-0.80.70.7-0.7-0.9-0.60.6-0.6-0.8
Condit. Reinf. active-inactive response ratio1.82.13.2-1.81.81.8-1.8-0.8-1.31.3-1.3-0.3
Condit. Reinf. active responses0.10.10.4-0.20.10.1-0.1-0.6-0.20.2-0.2-0.7
Condit. Reinf. inactive responses0.70.91.31.1-1.1-1.21.20.30.9-0.90.9-0.1
Condit. Reinf. lever presses0.20.31.0-0.20.10.1-0.1-1.0-0.60.6-0.6-0.7
Condit. Reinf. lever reinforcers received0.10.20.7-0.10.00.0-0.0-0.8-0.30.3-0.3-0.8
Conditioned reinforcement - actives0.10.20.30.5-0.6-0.60.6-0.00.4-0.40.4-0.3
Conditioned reinforcement - inactives0.20.30.5-0.60.60.6-0.6-0.5-0.60.6-0.6-0.7
Conditioned locomotion0.10.10.90.2-0.2-0.30.3-0.2-0.10.1-0.1-1.0
Patch foraging indifference point 0 sec0.10.20.3-0.30.30.3-0.3-0.3-0.50.5-0.5-0.3
Patch foraging indifference point AUC0.10.10.2-0.10.00.0-0.0-0.5-0.50.5-0.5-0.2
Delay disc. indifference point, 0s delay0.10.10.10.1-0.2-0.10.20.00.3-0.30.30.3
Delay disc. indifference point, 16s delay1.82.03.41.7-1.8-1.81.80.11.1-1.11.1-1.0
Delay disc. indifference point, 2s delay0.40.50.70.6-0.5-0.50.50.80.8-0.80.80.4
Delay disc. indifference point, 24s delay4.04.56.52.1-2.0-1.91.92.52.4-2.42.40.7
Delay disc. indifference point, 4s delay0.40.40.70.5-0.4-0.40.40.50.8-0.80.80.8
Delay disc. indifference point, 8s delay0.70.81.50.7-0.6-0.60.61.21.2-1.21.20.3
Indifference point function ln k0.91.62.41.2-1.2-1.21.20.81.6-1.61.6-0.1
Indifference point function log k0.91.62.41.2-1.2-1.21.20.81.6-1.61.6-0.1
Patch foraging total patch changes 0 sec0.10.20.3-0.30.30.3-0.3-0.4-0.50.5-0.5-0.5
Patch foraging total patch changes 12 sec0.30.40.6-0.50.50.5-0.5-0.1-0.80.8-0.80.7
Patch foraging total patch changes 18 sec0.10.20.30.4-0.4-0.40.4-0.6-0.30.3-0.3-0.3
Patch foraging total patch changes 24 sec0.50.81.0-0.90.90.9-0.9-0.9-1.01.0-1.0-0.8
Patch foraging total patch changes 6 sec0.50.71.0-0.90.90.9-0.9-0.3-1.01.0-1.0-0.1
Patch foraging time to switch 0 sec0.30.50.70.9-0.8-0.80.80.80.6-0.60.60.6
Patch foraging water rate 0 sec1.22.53.7-1.71.61.6-1.6-1.9-1.51.5-1.5-1.1
Patch foraging water rate 12 sec0.20.41.8-0.20.20.1-0.1-1.1-0.20.2-0.2-1.3
Patch foraging water rate 18 sec0.40.72.8-0.40.30.3-0.3-1.4-0.60.6-0.6-1.7
Patch foraging water rate 24 sec1.52.15.3-1.10.90.9-0.9-2.3-1.41.4-1.4-2.2
Patch foraging water rate 6 sec0.10.10.5-0.1-0.0-0.00.0-0.50.3-0.30.3-0.7
Seeking ratio, delayed vs. immediate footshock1.11.31.6-1.21.21.1-1.1-1.3-1.21.2-1.2-0.3
Distance traveled before self-admin0.81.12.0-1.41.41.4-1.4-0.3-0.70.7-0.70.8
Distance traveled after self-admin0.70.91.7-0.70.60.6-0.6-1.3-1.21.2-1.2-0.2
Extensor digitorum longus weight0.20.72.60.2-0.3-0.30.3-1.5-0.60.6-0.6-1.6
Bone: elastic displacement1.11.32.0-1.41.41.4-1.4-0.5-1.01.0-1.0-0.5
Bone: elastic work6.28.114.8-3.73.83.8-3.8-0.8-2.22.2-2.2-0.4
Bone: endosteal estimation0.10.20.60.5-0.5-0.60.6-0.8-0.30.3-0.3-0.3
Bone: endosteal perimeter0.51.11.5-1.11.11.1-1.1-0.9-1.21.2-1.2-0.2
Epididymis fat weight0.93.15.2-1.71.51.5-1.5-2.3-1.71.7-1.7-2.1
Delta time in closed arm before/after self-admin0.40.40.70.7-0.8-0.80.8-0.70.1-0.10.1-0.7
Delta time in open arm before/after self-admin0.00.00.10.2-0.1-0.10.10.20.2-0.20.2-0.0
Diff in mean of infusions in LGA sessions0.30.42.5-0.50.50.5-0.50.1-0.00.0-0.01.6
Delay discount exponential model param2.12.33.3-1.51.51.5-1.5-1.4-1.81.8-1.8-0.4
Extinction: sum of active levers before priming0.60.71.50.6-0.5-0.50.51.21.1-1.11.10.2
Active lever presses in extinction session 61.51.54.6-0.10.30.3-0.32.11.5-1.51.51.3
Bone: final force4.36.810.4-3.23.23.2-3.2-2.1-2.02.0-2.0-2.2
Bone: final moment5.18.212.7-3.63.53.5-3.5-2.0-2.22.2-2.2-2.0
Food consumed during 24 hour testing period0.40.61.0-0.60.60.6-0.6-0.8-1.01.0-1.0-0.2
Glucose6.410.125.61.6-1.2-1.11.15.13.6-3.63.64.4
Heart weight0.71.12.1-1.41.41.4-1.4-0.2-0.70.7-0.7-0.1
Delay discount hyperbolic model param1.92.12.9-1.41.41.4-1.4-1.4-1.71.7-1.7-0.5
Intermittent access intake day 1-15 change0.51.11.6-1.21.31.3-1.3-0.2-1.11.1-1.10.6
Intermittent access intake escalation0.50.91.4-1.11.21.2-1.2-0.2-1.01.0-1.00.4
Intermittent access intake escalation 22.02.33.7-1.81.91.9-1.9-0.1-1.11.1-1.11.5
Intermitt. access day 1 inactive lever presses0.93.56.8-1.61.51.4-1.4-2.1-2.02.0-2.0-2.6
Intermitt. access day 15 inactive lever presses0.61.12.8-0.50.50.4-0.4-1.4-1.21.2-1.2-1.7
Intermitt. access escalation Index0.40.61.4-0.30.20.2-0.2-1.2-0.90.9-0.9-1.0
Intermittent access day 1 total infusions0.10.10.4-0.20.20.2-0.2-0.2-0.30.3-0.3-0.6
Intermittent access day 15 total infusions0.50.71.1-0.80.80.8-0.8-0.6-1.01.0-1.0-0.4
Intermittent access terminal intake (last 3 days)0.81.11.5-1.11.11.1-1.1-0.6-1.21.2-1.20.3
Intermittent access total infusions0.20.30.4-0.50.50.5-0.5-0.4-0.60.6-0.6-0.5
Intermittent access day 1 locomotion0.10.10.90.2-0.2-0.20.2-0.10.3-0.30.3-0.9
Intermittent access day 15 total locomotion0.40.70.8-0.80.80.8-0.8-0.4-0.90.9-0.9-0.7
Intermittent access total locomotion0.20.20.8-0.40.40.4-0.4-0.3-0.40.4-0.4-0.9
Intermittent access standard deviation0.30.62.3-0.10.20.2-0.21.50.9-0.90.90.9
Left kidney weight0.00.20.3-0.50.50.6-0.60.60.2-0.20.2-0.3
Right kidney weight0.00.20.7-0.20.30.3-0.30.60.5-0.50.5-0.8
Cocaine induced anxiety1.31.83.8-1.81.92.0-2.01.00.4-0.40.40.7
Post-drug Anxiety1.01.02.7-0.80.91.0-1.01.60.9-0.90.90.7
Baseline Anxiety0.91.01.91.4-1.3-1.31.30.90.6-0.60.60.5
Tail length3.011.815.1-3.63.53.5-3.5-3.3-3.93.9-3.9-1.1
Length with tail1.45.910.0-3.13.13.2-3.2-1.2-2.02.0-2.00.0
Length without tail0.51.62.7-1.41.61.6-1.61.30.6-0.60.61.1
Times rat made contact with spout2.32.74.3-1.51.61.6-1.6-0.1-2.12.1-2.11.2
Lifetime Intake0.00.10.3-0.10.10.1-0.1-0.1-0.20.2-0.2-0.6
Liver weight, left0.81.32.40.9-0.8-0.80.71.41.5-1.51.50.5
Liver weight, right1.52.73.8-1.61.61.5-1.5-1.9-1.61.6-1.6-1.6
Locomotor activity0.61.01.11.0-1.0-1.01.01.01.0-1.01.00.8
Locomotor testing distance1.42.63.41.8-1.8-1.81.80.91.7-1.71.70.4
Locomotor testing rearing0.40.71.41.1-1.2-1.21.20.10.5-0.50.50.3
Locomotion in novel chamber0.40.50.80.8-0.9-0.90.90.00.6-0.60.6-0.9
Locomotion in novel chamber post-restriction2.94.76.1-2.32.22.2-2.2-1.9-2.52.5-2.5-0.9
Fecal boli incidents, locomotor time 10.30.40.80.9-0.9-0.90.90.20.3-0.30.3-0.4
Change in fecal boli incidents, locomotor task1.81.86.20.5-0.4-0.40.32.01.3-1.31.32.5
Time >=10cm from walls, locomotor time 11.21.32.8-0.40.20.2-0.2-1.7-1.41.4-1.4-1.5
Bouts of movement, locomotor time 11.41.62.11.2-1.2-1.11.11.41.5-1.51.50.6
Total resting periods, locomotor time 11.71.92.61.3-1.2-1.21.21.61.6-1.61.61.0
Rest time, locomotor task time 10.40.61.50.3-0.2-0.20.21.20.8-0.80.81.1
Distance moved, locomotor task time 10.20.30.8-0.50.40.4-0.4-0.9-0.60.6-0.6-0.1
Vertical activity count, locomotor time 10.30.82.3-0.70.60.5-0.5-1.5-0.90.9-0.9-0.9
Time >=10cm from walls, locomotor time 20.10.10.2-0.20.20.2-0.2-0.2-0.50.5-0.5-0.2
Bouts of movement, locomotor time 20.81.31.71.2-1.2-1.21.20.71.3-1.31.3-0.5
Total resting periods, locomotor time 20.50.91.31.1-1.1-1.11.10.20.9-0.90.9-0.9
Rest time, locomotor task time 20.00.10.10.2-0.2-0.20.20.00.3-0.30.30.3
Distance moved, locomotor task time 20.00.00.2-0.0-0.0-0.00.00.00.0-0.00.00.4
Vertical activity count, locomotor time 20.10.10.30.2-0.2-0.20.2-0.5-0.00.0-0.0-0.6
Light reinforcement 10.71.74.8-0.70.60.5-0.5-2.2-1.41.4-1.4-1.7
Light reinforcement 21.32.03.8-1.31.21.2-1.2-2.0-1.41.4-1.4-1.6
Bone: marrow area0.10.20.60.5-0.5-0.60.6-0.8-0.30.3-0.3-0.3
Bone: maximum diameter0.91.62.6-1.61.61.6-1.6-0.9-0.80.8-0.8-1.2
Bone: maximum force4.17.210.6-3.33.23.2-3.1-2.3-2.22.2-2.2-2.2
Bone: maximum moment4.78.312.6-3.53.53.5-3.5-2.2-2.42.4-2.4-2.0
Mean time between licks in bursts0.82.02.51.6-1.6-1.61.61.11.6-1.61.60.3
Mean num. licks in bursts0.50.81.2-0.91.01.0-1.00.4-0.80.8-0.81.1
Cd content in liver0.50.51.11.0-1.0-1.11.1-0.40.3-0.30.3-0.4
Co content in liver0.00.10.2-0.10.10.1-0.1-0.0-0.40.4-0.4-0.1
Cu content in liver0.91.01.9-1.31.31.4-1.40.0-0.80.8-0.80.3
Fe content in liver0.60.71.01.0-1.0-1.01.00.20.8-0.80.8-0.1
K content in liver1.41.43.9-0.40.30.3-0.3-2.0-1.31.3-1.3-1.7
Mg content in liver1.21.33.80.4-0.5-0.60.6-2.0-1.11.1-1.1-1.7
Mn content in liver0.00.00.2-0.20.10.1-0.1-0.3-0.10.1-0.1-0.5
Na content in liver0.20.20.40.4-0.5-0.50.5-0.50.1-0.10.1-0.6
Rb content in liver1.92.24.6-1.00.90.8-0.8-2.1-1.71.7-1.7-1.6
Se content in liver0.40.50.9-0.40.40.4-0.4-0.8-0.90.9-0.9-0.5
Sr content in liver0.50.41.5-0.20.30.3-0.31.20.5-0.50.51.1
Zn content in liver1.61.83.0-1.11.01.0-1.0-1.5-1.71.7-1.7-0.8
Bone: minimum diameter2.54.66.5-2.62.52.5-2.5-1.5-1.91.9-1.9-1.4
Time in familiar zone, hab. session 10.10.10.2-0.20.30.3-0.30.40.0-0.00.00.4
Time in novel zone, hab. session 10.00.00.10.2-0.2-0.20.2-0.3-0.00.0-0.0-0.2
Total zone transitions, hab. session 10.30.40.50.7-0.7-0.70.70.20.7-0.70.7-0.1
Total locomotion distance, hab. session 10.10.21.00.1-0.1-0.10.1-0.6-0.10.1-0.1-1.0
Locomotion velocity, hab. session 10.10.21.20.1-0.1-0.10.1-0.7-0.10.1-0.1-1.1
Time in familiar zone, hab. session 20.20.20.40.6-0.6-0.60.60.20.3-0.30.30.0
Time in novel zone, hab. session 20.10.10.10.1-0.1-0.10.10.10.4-0.40.4-0.1
Total zone transitions, hab. session 20.60.81.80.9-1.0-1.11.1-1.00.1-0.10.1-1.4
Total locomotion distance, hab. session 20.81.04.10.1-0.3-0.30.3-1.8-0.70.7-0.7-2.0
Locomotion velocity, hab. session 20.91.24.4-0.2-0.0-0.10.1-2.0-0.90.9-0.9-2.1
Novel to familiar place preference ratio2.52.74.8-2.12.22.2-2.2-0.5-1.31.3-1.30.1
Novelty place preference2.42.64.7-2.12.22.2-2.2-0.4-1.31.3-1.30.2
Time in novel zone, NPP test1.92.13.7-1.91.91.9-1.9-0.4-1.11.1-1.10.1
Total zone transitions, NPP test1.01.52.51.4-1.5-1.61.6-1.10.3-0.30.3-1.6
Total locomotion distance, NPP test1.01.34.90.7-0.9-0.91.0-1.8-0.40.4-0.4-2.2
Locomotion velocity, NPP test0.71.04.00.4-0.5-0.60.6-1.7-0.60.6-0.6-2.0
Intraocular pressure0.81.21.9-1.00.90.9-0.9-1.4-1.31.3-1.3-0.7
Delta distance traveled before/after self-admin0.30.30.70.8-0.8-0.80.8-0.40.1-0.10.1-0.3
Delta ambulatory time before/after self-admin0.91.12.31.4-1.5-1.51.5-0.10.5-0.50.5-0.2
Parametrial fat weight0.61.52.3-0.90.80.8-0.8-1.5-1.51.5-1.5-1.5
Pavlov. Cond. lever latency1.01.32.51.5-1.5-1.61.6-0.40.6-0.60.6-0.8
Pavlov. Cond. magazine entry latency2.22.85.1-2.22.22.3-2.3-0.2-1.31.3-1.30.5
Pavlov. Cond. change in total contacts0.60.61.2-0.91.11.1-1.10.9-0.10.1-0.10.7
Pavlov. Cond. index score2.73.45.7-2.32.42.4-2.4-0.7-1.61.6-1.60.0
Pavlov. Cond. latency score2.22.84.9-2.12.22.2-2.2-0.3-1.41.4-1.40.4
Pavlov. Cond. lever contacts0.60.81.4-1.11.21.2-1.2-0.1-0.60.6-0.60.3
Pavlov. Cond. magazine entry number2.63.36.22.4-2.5-2.52.5-0.31.2-1.21.2-1.0
Pavlov. Cond. intertrial magazine entries0.50.61.6-0.10.00.0-0.0-1.3-0.80.8-0.8-1.2
Pavlov. Cond. lever-magazine prob. diff.2.63.25.4-2.32.32.3-2.3-0.6-1.61.6-1.6-0.0
Pavlov. Cond. response bias1.92.34.5-2.02.12.1-2.10.2-1.01.0-1.00.8
Pavlov. Cond. lever latency0.91.23.00.6-0.5-0.40.41.71.4-1.41.40.9
Pavlov. Cond. magazine entry latency1.61.93.51.8-1.9-1.91.90.21.0-1.01.00.0
Pavlov. Cond. change in total contacts0.20.30.50.7-0.7-0.70.7-0.40.0-0.00.0-0.3
Pavlov. Cond. index score0.20.20.40.6-0.6-0.60.7-0.5-0.10.1-0.1-0.2
Pavlov. Cond. latency score0.20.30.50.6-0.7-0.70.7-0.6-0.20.2-0.2-0.4
Pavlov. Cond. lever contacts0.71.02.6-0.40.30.3-0.3-1.6-1.31.3-1.3-0.8
Pavlov. Cond. magazine entry number1.01.32.4-1.51.51.5-1.5-0.1-0.90.9-0.90.1
Pavlov. Cond. intertrial magazine entries1.32.02.3-1.41.41.3-1.3-1.5-1.51.5-1.5-1.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.8-0.8-0.90.9-0.30.1-0.10.1-0.1
Pavlov. Cond. response bias0.10.20.70.3-0.3-0.40.4-0.8-0.30.3-0.3-0.3
Time in closed arm before self-admin0.30.41.30.00.10.1-0.11.20.8-0.80.80.6
Time in closed arm after self-admin0.70.81.60.5-0.4-0.40.41.21.2-1.21.20.9
Time in open arm before self-admin0.40.40.90.4-0.5-0.50.5-0.9-0.60.6-0.6-0.7
Time in open arm after self-admin0.10.20.60.3-0.4-0.40.4-0.5-0.20.2-0.2-0.8
Bone: periosteal estimation1.12.33.1-1.81.71.7-1.7-1.4-1.31.3-1.3-1.4
Bone: periosteal perimeter2.74.68.6-2.82.92.9-2.9-0.6-1.61.6-1.6-0.2
Bone: post-yield work0.00.10.10.3-0.3-0.30.3-0.30.1-0.10.1-0.2
Progressive ratio test 1 active lever presses0.30.30.5-0.50.50.5-0.5-0.6-0.70.7-0.7-0.7
Progressive ratio test 1 breakpoint0.30.40.6-0.60.60.6-0.6-0.6-0.80.8-0.8-0.7
Progressive ratio test 1 inactive lever presses2.43.45.1-1.51.41.4-1.4-2.3-2.12.1-2.1-2.1
Progressive ratio test 2 active lever presses0.30.40.7-0.50.40.4-0.4-0.6-0.70.7-0.7-0.8
Progressive ratio test 2 breakpoint0.30.40.6-0.50.50.5-0.5-0.6-0.70.7-0.7-0.8
Progressive ratio test 2 inactive lever presses0.20.30.5-0.70.70.7-0.7-0.2-0.50.5-0.5-0.2
Incentive Sensitization - Responses0.30.40.7-0.50.50.4-0.4-0.7-0.80.8-0.8-0.6
Incentive Sensitization - Breakpoint0.30.40.6-0.50.40.4-0.4-0.6-0.80.8-0.8-0.5
Sum of active levers in priming session hrs 5-61.00.91.6-1.21.31.3-1.30.4-0.40.4-0.41.2
Progressive ratio0.61.01.11.1-1.0-1.01.01.01.1-1.11.10.3
Food seeking constrained by brief footshock0.20.21.0-0.00.10.1-0.11.00.3-0.30.30.6
Seeking ratio, punishment vs. effort0.20.30.7-0.30.30.3-0.3-0.6-0.60.6-0.6-0.8
Retroperitoneal fat weight2.611.014.9-3.12.92.8-2.8-3.9-3.63.6-3.6-3.3
Reaction time number correct0.91.85.50.9-1.1-1.21.2-2.4-0.30.3-0.3-2.3
Reaction time mean minus median0.10.31.10.10.00.0-0.00.90.3-0.30.31.1
Reaction time mean minus median AUC0.00.10.3-0.00.00.0-0.00.30.2-0.20.20.5
Reaction time num false alarms0.10.10.20.5-0.4-0.40.40.50.1-0.10.10.1
Reaction time num false alarms AUC0.30.50.80.9-0.9-0.90.90.60.5-0.50.5-0.0
Reaction time trials correct on left0.91.85.50.9-1.1-1.21.2-2.4-0.30.3-0.3-2.3
Reaction time trials on left1.01.85.70.9-1.1-1.21.2-2.4-0.30.3-0.3-2.3
Reaction time mean0.20.30.4-0.50.40.4-0.4-0.6-0.60.6-0.6-0.1
Reaction time mean AUC0.10.20.6-0.20.10.1-0.1-0.8-0.50.5-0.5-0.5
Median of all reaction times0.30.40.7-0.50.40.4-0.4-0.9-0.70.7-0.7-0.5
Reaction time omissions0.10.10.3-0.00.0-0.0-0.0-0.5-0.40.4-0.4-0.3
Reaction time false alarm rate0.40.62.80.3-0.2-0.20.21.70.5-0.50.51.2
Reaction time premature initiation rate0.91.31.61.3-1.2-1.21.21.11.2-1.21.20.3
Reaction time premature initiations0.81.52.71.5-1.6-1.61.7-0.30.8-0.80.8-1.0
Std. dev. reaction times0.20.30.40.6-0.6-0.60.60.50.4-0.40.40.6
Reaction time trials completed1.01.85.70.9-1.1-1.21.2-2.4-0.30.3-0.3-2.3
Reaction time trials AUC1.01.85.80.9-1.1-1.21.2-2.4-0.40.4-0.4-2.3
Run reversals in cocaine runway, females0.60.61.11.0-1.0-1.11.1-0.10.4-0.40.4-1.0
Run reversals in cocaine runway, males1.61.62.7-1.61.61.7-1.7-0.2-1.01.0-1.00.8
Latency to leave start box in cocaine runway0.30.30.70.8-0.8-0.80.80.10.4-0.40.40.1
Latency to leave start box in cocaine runway, F0.70.81.61.1-1.2-1.31.3-0.7-0.00.0-0.0-0.9
Latency to leave start box in cocaine runway, M0.20.20.8-0.20.30.3-0.30.60.3-0.30.30.9
Std. dev. time between licks in bursts0.91.24.60.3-0.5-0.60.6-2.1-0.60.6-0.6-2.1
Total sessions with >9 infusions0.30.40.50.7-0.7-0.70.70.60.6-0.60.6-0.2
Short access day 1 total inactive lever presses0.30.31.80.5-0.5-0.50.6-0.40.1-0.10.1-1.3
Short access day 10 total inactive lever presses1.43.34.6-1.81.71.7-1.7-2.1-2.02.0-2.0-1.2
Short access day 1 total infusions1.41.82.31.5-1.5-1.51.51.21.4-1.41.4-0.0
Short access day 10 total infusions1.01.31.7-1.21.21.2-1.2-0.6-1.31.3-1.3-0.4
Short access total infusions0.00.00.10.2-0.2-0.20.20.30.2-0.20.2-0.3
Short access day 1 locomotion0.30.31.00.3-0.2-0.20.21.00.7-0.70.70.4
Short access day 10 total locomotion0.30.51.6-0.20.30.4-0.41.20.6-0.60.61.3
Short access total locomotion0.20.20.8-0.20.30.3-0.30.90.4-0.40.40.4
One hour access (0.3 mA shock)0.40.51.0-0.40.40.3-0.3-0.8-0.80.8-0.8-1.0
Compulsive drug intake0.60.72.2-0.40.30.2-0.2-1.5-0.80.8-0.8-1.5
One hour access (shock baseline)0.00.10.2-0.0-0.0-0.00.0-0.2-0.40.4-0.4-0.2
Social response proportion0.40.40.60.8-0.8-0.80.80.10.6-0.60.6-0.1
Social responses0.30.40.50.7-0.7-0.70.70.10.7-0.70.7-0.6
Social time0.20.20.30.5-0.5-0.50.50.00.6-0.60.6-0.5
Soleus weight1.23.54.5-2.01.91.9-1.9-1.8-2.12.1-2.1-0.9
Bone: stiffness0.40.62.1-0.90.80.8-0.8-0.8-0.00.0-0.0-1.4
Tibialis anterior weight0.00.20.40.1-0.2-0.20.2-0.7-0.40.4-0.4-0.6
Time to tail flick, vehicle, before self-admin0.10.10.20.5-0.5-0.50.50.30.1-0.10.1-0.2
Time to tail flick, vehicle, after self-admin2.02.73.51.8-1.7-1.71.71.21.9-1.91.9-0.1
Time to tail flick, test, before self-admin0.10.10.20.2-0.2-0.20.20.40.2-0.20.2-0.1
Time to tail flick, test, after self-admin1.11.12.10.8-0.7-0.70.71.41.4-1.41.40.8
Delta time to tail flick, vehicle, before/after SA0.20.20.30.5-0.5-0.60.6-0.30.4-0.40.4-0.4
Delta time to tail flick, test, before/after SA0.70.71.50.3-0.3-0.20.21.21.1-1.11.11.2
Tibia length7.620.933.9-5.85.85.8-5.8-2.6-3.83.8-3.8-1.6
Ambulatory time before self-admin1.72.54.1-2.02.02.0-2.0-0.8-1.31.3-1.30.1
Ambulatory time after self-admin0.50.50.9-0.60.50.5-0.5-0.9-1.01.0-1.0-0.3
Bone: tissue strength1.61.62.6-1.21.11.1-1.1-1.6-1.21.2-1.2-1.6
Total heroin consumption0.50.61.1-0.40.50.6-0.61.11.0-1.01.00.8
Bone: trabecular number0.10.10.2-0.20.20.2-0.2-0.1-0.50.5-0.50.1
Bone: trabecular spacing0.71.03.70.5-0.6-0.70.7-1.8-0.30.3-0.3-1.9
Bone: trabecular thickness1.21.52.5-1.41.61.6-1.60.6-0.90.9-0.91.2
Bone: trabecular tissue density0.81.11.51.2-1.2-1.21.20.81.1-1.11.10.4
Water consumed over 24 hours0.20.31.4-0.20.30.3-0.30.8-0.20.2-0.21.2
Number of responses in last shaping day0.20.20.40.3-0.3-0.30.30.30.6-0.60.6-0.6