Hub : Genes

Dpysl5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Dpysl5 0.04 0.03 6.9e-05 0.05 0.04 0.04 0.05 1.5e-05 4.7e-05 4.4e-05 2.8e-05
2 IC gene expression Dpysl5 0.24 0.15 2.0e-09 0.18 0.21 0.21 0.21 6.1e-08 3.0e-09 4.7e-09 4.4e-09
3 Liver gene expression Dpysl5 0.34 0.16 0.0e+00 0.32 0.32 0.32 0.32 8.2e-36 2.0e-36 1.8e-36 1.4e-36
4 Eye gene expression Dpysl5 0.86 0.05 1.4e-09 0.25 0.26 0.24 0.28 9.3e-05 7.5e-05 1.4e-04 2.8e-05
5 OFC gene expression Dpysl5 0.36 0.16 1.9e-09 0.31 0.32 0.33 0.34 3.7e-08 2.3e-08 1.6e-08 6.5e-09
6 NAcc mRNA stability Dpysl5 0.05 0.03 9.3e-11 0.06 0.07 0.06 0.06 6.4e-09 1.5e-10 5.3e-10 1.1e-09
7 Liver mRNA stability Dpysl5 0.08 0.07 9.7e-08 0.06 0.05 0.05 0.05 1.0e-06 1.5e-06 1.4e-06 1.6e-06
8 PL mRNA stability Dpysl5 0.05 0.03 1.4e-06 0.06 0.05 0.06 0.06 6.4e-07 3.3e-06 8.3e-07 9.4e-07
9 pVTA mRNA stability Dpysl5 0.03 0.02 4.4e-03 0.01 0.02 0.04 0.01 2.5e-02 7.8e-03 6.4e-04 2.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density3.15.77.4-2.22.32.7-2.02.6-2.6-1.92.72.3
Area under the delay curve0.10.21.40.00.10.30.10.1-0.20.20.11.2
BMI with tail1.03.46.62.4-2.0-1.61.9-1.81.42.6-1.2-0.9
BMI without tail0.73.65.82.3-2.1-1.82.1-2.01.72.4-1.6-0.2
Body weight2.611.413.83.7-3.4-3.43.7-3.43.33.3-3.3-3.0
Weight adjusted by age0.10.10.5-0.50.00.2-0.70.2-0.20.30.5-0.4
Bone surface1.22.33.9-1.21.21.9-0.91.6-1.8-0.62.01.8
Bone volume1.42.74.1-1.31.62.0-1.01.9-1.9-1.32.01.6
Breakpoint value in progressive ratio session0.50.91.8-0.51.00.7-0.61.2-1.0-0.71.31.2
Number of licking bursts0.20.71.71.3-0.9-0.30.9-0.70.31.3-0.20.6
Context. condit. distance diff. score0.10.10.3-0.20.40.2-0.50.3-0.2-0.60.0-0.4
Locomotion velocity, session 10.30.40.90.9-0.7-0.10.8-0.50.30.9-0.40.2
Locomotion distance, session 10.81.02.2-0.70.81.5-0.51.0-1.2-0.71.20.8
Locomotion velocity, session 20.30.41.10.5-0.4-0.50.5-0.60.50.1-0.8-1.1
Locomotion distance, session 20.00.10.2-0.0-0.20.00.4-0.20.10.3-0.1-0.5
Locomotion velocity, session 30.60.71.6-1.00.60.8-1.30.8-0.9-0.11.10.6
Locomotion distance, session 30.30.30.7-0.60.20.8-0.50.4-0.70.30.80.6
Stereotopy head waving bouts, day 32.22.63.2-1.61.81.4-1.71.8-1.7-1.61.80.9
Stereotopy head waving duration, day 30.30.40.7-0.40.80.3-0.70.8-0.6-0.90.7-0.1
Locomotion velocity, session 70.50.61.3-0.50.50.8-0.20.7-0.90.11.11.1
Locomotion distance, session 70.30.41.30.7-0.6-0.10.9-0.20.11.10.30.5
Stereotopy head waving bouts, day 70.10.10.7-0.1-0.0-0.0-0.5-0.1-0.00.0-0.0-0.9
Stereotopy head waving duration, day 70.50.61.8-1.10.80.6-1.40.6-0.7-0.70.60.1
Locomotion velocity, session 80.30.40.6-0.60.70.6-0.80.7-0.6-0.70.50.5
Locomotion distance, session 80.20.30.6-0.50.60.7-0.50.7-0.6-0.60.60.4
Degree of sensitization distance1.11.22.21.5-1.0-1.11.4-0.91.00.9-0.9-0.6
Degree of sensitization stereotypy0.40.41.60.3-0.6-0.6-0.0-0.70.60.5-0.7-1.2
Conditioned locomotion3.84.57.1-2.22.02.0-2.32.1-2.0-1.81.92.7
Cocaine response after cond. corrected0.30.40.9-0.10.50.7-0.10.8-0.7-0.40.90.8
Cocaine response after cond. not corrected0.71.11.7-0.71.01.3-0.81.1-1.2-0.91.21.0
Cocaine response before conditioning2.02.44.1-2.01.71.6-2.01.3-1.5-1.80.80.8
Saline control response0.91.22.1-1.31.21.0-1.51.2-1.0-1.21.00.3
Bone: connectivity density2.94.66.7-2.02.02.4-1.82.3-2.4-1.42.62.2
Bone: cortical apparent density0.20.31.1-0.10.40.7-0.30.6-0.6-0.20.71.0
Bone: cortical area0.10.20.5-0.00.20.70.00.4-0.60.20.70.6
Bone: cortical porosity2.02.23.4-1.81.61.5-1.81.4-1.4-1.71.10.1
Bone: cortical porosity1.82.02.7-1.61.61.5-1.51.4-1.4-1.61.20.4
Bone: cortical thickness0.10.20.50.4-0.5-0.10.5-0.50.30.7-0.30.2
Bone: cortical thickness0.91.12.7-0.80.81.2-0.61.0-1.2-0.41.31.6
Bone: cortical tissue density0.10.20.70.10.30.5-0.10.5-0.5-0.10.60.8
Condit. Reinf. active minus inactive responses1.21.42.21.5-1.3-1.11.3-1.11.11.5-0.9-0.5
Condit. Reinf. active-inactive response ratio1.11.21.91.3-1.2-1.21.4-1.11.11.3-0.9-0.3
Condit. Reinf. active responses0.10.10.40.3-0.10.20.2-0.0-0.10.40.20.6
Condit. Reinf. inactive responses1.01.32.2-1.01.21.5-1.11.2-1.3-1.01.10.8
Incentive salience index mean0.10.10.40.6-0.3-0.20.6-0.10.10.50.1-0.1
Condit. Reinf. lever presses0.40.71.1-0.61.00.9-0.41.0-0.9-1.00.90.0
Condit. Reinf. active minus inactive responses2.94.48.3-2.51.72.2-2.91.7-2.1-1.01.92.3
Condit. Reinf. active-inactive response ratio0.81.34.6-1.40.91.2-2.10.8-1.1-0.70.80.7
Condit. Reinf. active responses2.63.75.7-2.31.52.0-2.31.6-2.0-0.72.02.4
Condit. Reinf. inactive responses1.01.43.9-1.10.91.2-0.51.2-1.3-0.31.52.0
Condit. Reinf. lever presses2.02.94.5-2.11.51.8-2.01.4-1.6-1.21.42.1
Condit. Reinf. lever reinforcers received2.53.55.6-2.31.51.9-2.41.5-1.9-0.71.82.3
Conditioned reinforcement - actives1.45.58.2-2.52.61.9-2.42.5-2.0-2.91.92.2
Conditioned reinforcement - inactives1.64.56.7-1.62.52.0-1.82.4-2.2-2.62.01.8
Conditioned locomotion1.01.52.8-1.51.40.8-1.41.3-1.0-1.71.00.5
Patch foraging indifference point 0 sec0.61.77.71.1-1.0-1.00.9-0.91.01.0-0.6-2.8
Patch foraging indifference point AUC0.40.93.90.10.31.2-0.20.6-1.10.41.12.0
Delay disc. indifference point, 0s delay2.62.94.51.8-1.6-1.82.1-1.71.81.1-2.0-1.1
Delay disc. indifference point, 16s delay0.10.10.6-0.3-0.10.3-0.3-0.0-0.10.40.10.8
Delay disc. indifference point, 2s delay0.20.20.40.5-0.5-0.40.5-0.50.40.5-0.6-0.1
Delay disc. indifference point, 24s delay0.81.22.1-1.21.31.2-1.01.1-1.0-1.40.70.8
Delay disc. indifference point, 4s delay0.20.20.90.4-0.2-0.00.5-0.10.00.5-0.10.9
Delay disc. indifference point, 8s delay0.00.10.5-0.20.10.2-0.10.1-0.1-0.10.10.7
Indifference point function ln k0.30.82.4-1.21.00.4-0.90.8-0.4-1.50.3-0.6
Indifference point function log k0.30.82.4-1.21.00.4-0.90.8-0.4-1.50.3-0.6
Patch foraging total patch changes 0 sec0.61.88.21.2-1.0-1.01.0-1.00.91.1-0.7-2.9
Patch foraging total patch changes 12 sec1.62.13.21.7-1.4-1.31.6-1.41.21.5-1.2-1.8
Patch foraging total patch changes 18 sec0.40.92.31.2-1.0-0.50.9-0.70.51.5-0.2-1.0
Patch foraging total patch changes 24 sec0.51.62.41.3-1.4-1.21.2-1.41.21.5-1.2-1.2
Patch foraging total patch changes 6 sec0.81.33.61.4-1.3-0.71.0-1.20.71.9-0.5-1.1
Patch foraging time to switch 0 sec0.00.20.40.4-0.4-0.50.2-0.40.30.6-0.2-0.3
Patch foraging water rate 0 sec0.20.61.3-1.10.80.5-0.80.5-0.4-1.10.2-0.9
Patch foraging water rate 12 sec0.20.71.70.1-0.7-1.00.5-0.91.20.2-1.3-0.6
Patch foraging water rate 18 sec0.20.51.2-1.00.3-0.3-0.4-0.20.4-1.1-0.9-0.9
Patch foraging water rate 24 sec0.91.32.40.6-0.9-1.60.8-1.11.40.5-1.5-1.3
Patch foraging water rate 6 sec0.40.61.8-0.1-0.4-0.80.4-0.71.0-0.4-1.4-1.0
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.0-0.2-0.1-0.0-0.30.10.3-0.2-0.3
Distance traveled before self-admin0.10.20.7-0.60.10.3-0.2-0.00.0-0.5-0.40.8
Distance traveled after self-admin1.12.03.01.4-1.5-1.31.7-1.51.61.1-1.7-0.6
Extensor digitorum longus weight3.714.917.2-4.13.74.1-4.13.9-4.1-2.84.13.8
Bone: elastic displacement1.11.42.0-1.01.31.0-0.91.4-1.0-1.41.31.1
Bone: elastic work0.91.22.4-0.81.01.2-0.71.2-1.0-0.81.41.6
Bone: endosteal estimation0.30.71.5-0.40.81.0-0.11.0-1.1-0.51.21.0
Bone: endosteal perimeter0.10.20.5-0.10.30.60.10.5-0.6-0.10.70.7
Epididymis fat weight11.156.263.97.7-7.8-8.07.6-7.77.77.3-7.2-6.2
Delta time in closed arm before/after self-admin0.20.20.90.6-0.2-0.20.2-0.10.00.60.3-0.9
Delta time in open arm before/after self-admin0.10.10.3-0.10.20.2-0.20.3-0.3-0.10.40.6
Diff in mean of infusions in LGA sessions0.00.10.30.3-0.10.00.20.2-0.10.20.5-0.4
Delay discount exponential model param0.20.31.80.3-0.4-0.60.3-0.40.50.1-0.4-1.3
Extinction: sum of active levers before priming0.20.30.60.10.80.3-0.20.7-0.6-0.60.5-0.6
Active lever presses in extinction session 61.11.11.8-1.01.30.8-1.01.2-1.0-1.31.00.6
Bone: final force0.00.10.10.30.00.30.30.1-0.30.20.30.3
Bone: final moment0.10.10.30.30.10.40.30.2-0.30.20.40.5
Food consumed during 24 hour testing period0.10.10.7-0.1-0.10.4-0.20.1-0.30.30.30.8
Glucose0.40.71.40.9-1.0-0.70.8-0.80.71.2-0.5-0.8
Heart weight2.64.26.02.1-1.8-2.12.3-2.12.11.1-2.5-2.1
Delay discount hyperbolic model param0.10.21.2-0.0-0.2-0.40.0-0.20.3-0.1-0.3-1.1
Intermittent access intake day 1-15 change0.10.61.6-1.10.80.7-0.80.7-0.6-1.30.40.4
Intermittent access intake escalation0.00.20.8-0.70.40.4-0.40.3-0.2-0.90.10.3
Intermittent access intake escalation 20.00.10.3-0.40.00.3-0.20.1-0.1-0.2-0.00.6
Intermitt. access day 1 inactive lever presses0.11.52.2-1.21.31.2-1.51.2-1.3-1.21.20.8
Intermitt. access day 15 inactive lever presses0.84.56.8-1.61.92.6-2.02.1-2.5-1.32.52.3
Intermitt. access escalation Index0.82.65.82.0-1.9-1.21.6-1.61.12.4-0.8-1.2
Intermittent access day 1 total infusions1.85.36.1-2.42.42.3-2.52.4-2.3-2.12.32.1
Intermittent access day 15 total infusions1.33.14.5-2.01.91.7-1.81.8-1.7-2.11.51.3
Intermittent access terminal intake (last 3 days)2.54.35.5-2.32.22.1-2.22.1-2.0-2.31.81.8
Intermittent access total infusions3.74.46.4-2.32.41.8-2.32.2-1.9-2.51.81.4
Intermittent access day 1 locomotion1.32.43.4-1.51.91.5-1.61.7-1.6-1.71.50.3
Intermittent access day 15 total locomotion0.10.40.7-0.50.60.5-0.70.7-0.6-0.60.70.8
Intermittent access total locomotion0.81.02.3-0.81.30.6-1.01.1-0.8-1.50.90.2
Intermittent access standard deviation0.42.02.7-1.31.61.5-1.41.6-1.4-1.61.40.3
Left kidney weight0.00.42.3-0.00.4-0.10.10.10.0-0.9-0.2-1.5
Right kidney weight0.31.94.91.3-0.9-1.41.5-1.21.40.1-1.6-2.2
Cocaine induced anxiety0.00.10.30.10.30.3-0.10.4-0.5-0.20.50.0
Post-drug Anxiety1.61.82.51.6-1.4-1.21.6-1.41.31.3-1.3-1.1
Baseline Anxiety2.23.74.61.8-2.1-1.92.0-2.12.12.0-1.9-1.0
Tail length0.10.71.60.6-0.6-0.91.0-0.91.00.0-1.3-0.8
Length with tail1.14.99.11.8-1.7-2.42.3-2.02.50.7-2.7-3.0
Length without tail0.42.08.71.1-0.7-1.31.3-0.91.30.2-1.2-2.9
Times rat made contact with spout1.31.52.1-1.21.11.3-1.31.2-1.3-0.71.51.3
Lifetime Intake3.84.87.3-2.32.51.8-2.32.4-2.0-2.72.01.3
Liver weight, left3.15.46.72.4-2.2-2.62.6-2.42.51.8-2.6-1.8
Liver weight, right7.913.918.73.6-3.3-4.13.9-3.84.02.3-4.3-3.9
Locomotor activity0.81.22.91.7-0.8-1.01.3-0.80.81.0-0.7-1.4
Locomotor testing distance0.10.20.70.8-0.1-0.10.20.1-0.20.70.6-0.2
Locomotor testing rearing0.30.92.4-0.51.10.7-1.01.2-1.1-0.61.5-0.2
Locomotion in novel chamber0.10.10.3-0.0-0.2-0.4-0.0-0.20.20.3-0.20.6
Locomotion in novel chamber post-restriction1.64.76.12.2-2.1-2.52.0-2.12.22.1-1.9-2.4
Fecal boli incidents, locomotor time 10.41.02.9-1.31.20.8-1.01.0-0.8-1.70.50.2
Change in fecal boli incidents, locomotor task3.94.25.42.3-2.1-2.12.3-2.02.12.0-1.9-1.2
Time >=10cm from walls, locomotor time 10.10.10.5-0.20.2-0.10.0-0.00.2-0.7-0.40.5
Bouts of movement, locomotor time 10.81.01.6-1.00.51.2-1.30.7-1.10.21.11.2
Total resting periods, locomotor time 11.11.32.3-1.10.61.4-1.30.8-1.20.21.31.5
Rest time, locomotor task time 10.00.10.3-0.0-0.4-0.10.1-0.30.20.5-0.10.2
Distance moved, locomotor task time 10.30.91.51.1-0.7-1.11.2-0.81.00.2-1.1-0.9
Vertical activity count, locomotor time 10.10.40.80.7-0.5-0.70.9-0.60.70.3-0.8-0.3
Time >=10cm from walls, locomotor time 20.30.81.8-0.91.10.8-0.70.9-0.8-1.30.41.1
Bouts of movement, locomotor time 20.10.20.50.3-0.7-0.20.1-0.60.40.7-0.5-0.5
Total resting periods, locomotor time 20.00.10.6-0.0-0.50.1-0.2-0.40.10.7-0.1-0.3
Rest time, locomotor task time 20.50.81.4-0.90.51.2-1.00.8-1.0-0.11.20.7
Distance moved, locomotor task time 20.50.61.20.9-0.5-1.01.1-0.70.90.1-1.1-0.1
Vertical activity count, locomotor time 20.10.20.60.4-0.1-0.70.6-0.40.5-0.3-0.8-0.1
Light reinforcement 10.73.25.5-1.51.62.3-1.91.9-2.2-0.92.4-0.0
Light reinforcement 21.22.84.5-1.71.42.1-1.71.7-1.9-1.11.81.5
Bone: marrow area0.30.71.5-0.40.81.0-0.11.0-1.1-0.51.21.0
Bone: maximum diameter0.30.71.8-0.30.61.1-0.10.9-1.1-0.01.30.9
Bone: maximum force0.00.10.30.00.20.5-0.00.3-0.4-0.10.40.2
Bone: maximum moment0.10.20.4-0.10.30.6-0.00.4-0.5-0.10.60.5
Mean time between licks in bursts0.53.24.11.7-1.8-2.02.0-1.92.01.3-2.0-1.3
Mean num. licks in bursts0.41.12.5-1.61.10.7-1.21.0-0.7-1.40.70.1
Cd content in liver0.10.10.90.3-0.0-0.10.20.1-0.00.00.2-1.0
Co content in liver5.46.37.6-2.52.62.8-2.32.6-2.7-2.72.51.9
Cu content in liver0.20.20.5-0.30.60.5-0.30.4-0.4-0.70.20.3
Fe content in liver1.21.52.6-0.71.61.3-0.91.4-1.3-1.61.20.3
K content in liver0.10.10.40.6-0.10.50.50.0-0.30.10.30.0
Mg content in liver0.40.42.00.80.10.50.60.2-0.4-0.30.4-1.4
Mn content in liver0.40.41.80.8-0.4-0.20.6-0.1-0.00.70.5-1.3
Na content in liver1.01.12.5-1.01.21.2-0.81.0-1.0-1.60.60.9
Rb content in liver0.20.31.20.9-0.2-0.20.6-0.10.10.30.0-1.1
Se content in liver0.40.42.50.8-0.3-0.40.4-0.30.20.2-0.2-1.6
Sr content in liver0.10.10.3-0.2-0.1-0.10.1-0.20.3-0.3-0.40.5
Zn content in liver1.21.33.31.3-0.9-0.81.5-1.01.00.5-1.0-1.8
Bone: minimum diameter0.30.51.31.0-0.7-0.51.1-0.60.40.8-0.2-0.6
Time in familiar zone, hab. session 10.91.01.71.3-0.9-1.01.3-0.80.80.9-0.8-1.1
Time in novel zone, hab. session 10.20.30.60.1-0.5-0.7-0.1-0.50.60.4-0.4-0.8
Total zone transitions, hab. session 10.10.20.2-0.50.40.4-0.50.5-0.4-0.30.4-0.1
Total locomotion distance, hab. session 10.20.30.9-0.30.80.5-0.20.7-0.5-0.90.50.4
Locomotion velocity, hab. session 10.91.31.7-0.81.31.2-0.81.3-1.2-1.31.11.2
Time in familiar zone, hab. session 20.10.10.40.4-0.3-0.1-0.0-0.20.10.70.1-0.3
Time in novel zone, hab. session 20.30.30.50.4-0.3-0.70.7-0.50.6-0.0-0.7-0.4
Total zone transitions, hab. session 20.00.10.30.1-0.20.20.2-0.0-0.10.50.2-0.2
Total locomotion distance, hab. session 20.10.10.30.0-0.30.4-0.0-0.0-0.20.60.30.3
Locomotion velocity, hab. session 20.10.10.3-0.2-0.10.6-0.20.1-0.40.40.50.5
Novel to familiar place preference ratio0.81.12.30.8-0.9-1.10.9-1.01.10.6-1.1-1.5
Novelty place preference1.21.62.91.0-1.2-1.41.1-1.31.40.8-1.3-1.7
Time in novel zone, NPP test1.51.83.61.0-1.2-1.51.1-1.31.40.8-1.4-1.9
Total zone transitions, NPP test1.11.62.5-1.31.31.6-1.21.3-1.4-1.11.30.7
Total locomotion distance, NPP test1.52.12.9-1.41.51.7-1.61.5-1.6-1.21.50.8
Locomotion velocity, NPP test2.33.34.6-1.71.82.2-1.92.0-2.0-1.52.01.3
Intraocular pressure5.48.811.13.3-2.9-3.33.1-2.83.02.5-2.8-2.8
Delta distance traveled before/after self-admin2.12.43.81.7-1.7-1.51.6-1.61.41.9-1.3-0.6
Delta ambulatory time before/after self-admin0.40.71.41.1-0.8-0.61.0-0.80.61.2-0.5-0.6
Parametrial fat weight14.133.144.35.7-6.7-5.45.8-6.45.86.5-5.6-3.2
Pavlov. Cond. lever latency0.81.11.70.7-1.0-1.30.8-1.21.30.7-1.3-0.6
Pavlov. Cond. magazine entry latency0.10.10.40.30.00.1-0.00.1-0.20.20.2-0.6
Pavlov. Cond. change in total contacts0.00.00.10.10.20.10.10.2-0.2-0.30.1-0.4
Pavlov. Cond. index score0.20.30.60.00.50.6-0.20.6-0.7-0.20.7-0.3
Pavlov. Cond. latency score0.20.20.60.00.40.6-0.20.6-0.7-0.10.8-0.3
Pavlov. Cond. lever contacts0.60.71.1-0.50.91.0-0.51.0-1.0-0.71.00.2
Pavlov. Cond. magazine entry number0.10.10.30.0-0.3-0.50.3-0.40.60.0-0.60.1
Pavlov. Cond. intertrial magazine entries1.61.92.6-1.31.51.4-1.21.4-1.3-1.61.21.4
Pavlov. Cond. lever-magazine prob. diff.0.60.71.2-0.40.91.0-0.61.0-1.1-0.61.10.2
Pavlov. Cond. response bias0.70.91.4-0.71.01.1-0.81.1-1.2-0.91.10.4
Pavlov. Cond. lever latency1.52.15.51.7-1.1-1.51.5-1.11.40.8-1.1-2.3
Pavlov. Cond. magazine entry latency0.40.64.1-0.70.10.6-0.40.2-0.50.30.42.0
Pavlov. Cond. change in total contacts0.51.24.8-1.10.50.9-1.20.7-0.90.00.92.2
Pavlov. Cond. index score1.11.86.2-1.50.81.3-1.30.9-1.2-0.41.02.5
Pavlov. Cond. latency score1.21.96.3-1.60.91.4-1.30.9-1.2-0.51.12.5
Pavlov. Cond. lever contacts0.91.43.4-1.40.91.2-1.30.8-1.1-0.60.91.8
Pavlov. Cond. magazine entry number0.40.53.70.40.1-0.50.2-0.00.3-0.5-0.3-1.9
Pavlov. Cond. intertrial magazine entries2.35.07.52.2-2.1-2.42.1-2.22.31.7-2.2-2.7
Pavlov. Cond. lever-magazine prob. diff.0.81.25.5-1.10.51.1-1.00.6-0.9-0.10.82.4
Pavlov. Cond. response bias1.72.37.2-1.61.11.6-1.51.1-1.4-0.71.12.7
Time in closed arm before self-admin0.40.61.20.8-0.7-1.10.8-0.60.90.5-0.6-0.9
Time in closed arm after self-admin0.91.02.11.1-1.0-1.40.9-0.71.11.2-0.6-0.6
Time in open arm before self-admin0.00.00.2-0.2-0.00.3-0.2-0.0-0.10.30.1-0.4
Time in open arm after self-admin0.70.81.3-0.70.81.1-0.80.8-1.1-0.60.90.8
Bone: periosteal estimation0.40.91.8-0.50.91.2-0.21.1-1.2-0.51.31.0
Bone: periosteal perimeter0.10.20.6-0.20.30.8-0.00.4-0.7-0.10.70.6
Bone: post-yield work1.11.92.8-1.51.61.3-1.41.5-1.4-1.71.3-0.0
Progressive ratio test 1 active lever presses1.52.74.4-1.62.01.3-1.71.8-1.5-2.11.51.0
Progressive ratio test 1 breakpoint1.62.74.6-1.62.01.3-1.71.8-1.5-2.11.50.9
Progressive ratio test 1 inactive lever presses2.25.77.7-2.22.72.2-2.42.5-2.3-2.82.22.1
Progressive ratio test 2 active lever presses1.21.64.2-1.51.60.8-1.31.3-0.9-2.00.70.7
Progressive ratio test 2 breakpoint1.11.43.8-1.41.50.7-1.21.2-0.8-2.00.60.6
Progressive ratio test 2 inactive lever presses1.03.34.9-1.82.11.6-1.81.9-1.7-2.21.51.5
Incentive Sensitization - Responses0.30.72.3-1.01.10.7-0.70.8-0.7-1.50.4-0.1
Incentive Sensitization - Breakpoint0.20.51.6-0.90.90.6-0.50.6-0.5-1.30.2-0.2
Sum of active levers in priming session hrs 5-60.20.20.50.6-0.10.30.4-0.0-0.30.70.30.5
Progressive ratio0.00.00.10.3-0.1-0.40.2-0.10.10.2-0.0-0.2
Food seeking constrained by brief footshock6.27.714.2-2.93.52.4-2.73.0-2.6-3.82.3-0.1
Seeking ratio, punishment vs. effort0.51.02.0-1.11.21.1-1.01.1-0.9-1.40.70.2
Retroperitoneal fat weight25.0111.9139.211.1-11.6-10.810.7-11.110.611.8-9.5-7.4
Reaction time number correct0.20.61.1-1.00.61.0-0.90.7-0.8-0.40.80.7
Reaction time mean minus median0.00.31.9-0.40.1-0.0-0.40.2-0.00.00.21.4
Reaction time mean minus median AUC0.00.10.30.1-0.3-0.30.1-0.10.30.3-0.10.5
Reaction time num false alarms0.61.02.71.1-1.1-0.60.9-0.80.51.6-0.2-1.4
Reaction time num false alarms AUC0.51.12.81.2-1.1-0.51.0-0.90.51.7-0.2-1.5
Reaction time trials correct on left0.20.61.1-1.00.61.0-0.90.7-0.8-0.40.80.7
Reaction time trials on left0.20.71.0-1.00.71.0-0.90.7-0.9-0.40.80.8
Reaction time mean0.40.91.90.9-0.8-1.21.1-0.91.20.2-1.40.1
Reaction time mean AUC0.30.71.60.8-0.7-1.11.0-0.81.10.1-1.30.0
Median of all reaction times0.71.22.41.1-0.8-1.21.4-1.01.30.1-1.5-0.4
Reaction time omissions0.00.10.20.4-0.1-0.10.20.1-0.10.40.20.3
Reaction time false alarm rate1.21.73.21.6-1.4-1.01.4-1.10.91.8-0.5-1.6
Reaction time premature initiation rate0.10.20.80.2-0.4-0.40.1-0.50.40.4-0.5-0.9
Reaction time premature initiations0.00.10.2-0.3-0.00.1-0.3-0.1-0.00.1-0.0-0.4
Std. dev. reaction times0.10.41.40.2-0.5-0.70.4-0.40.60.4-0.61.2
Reaction time trials completed0.20.71.0-1.00.71.0-0.90.7-0.9-0.40.80.8
Reaction time trials AUC0.20.81.4-1.20.71.1-1.10.8-1.0-0.50.90.8
Run reversals in cocaine runway, females0.10.20.6-0.70.30.1-0.30.20.0-0.8-0.20.4
Run reversals in cocaine runway, males0.40.40.8-0.90.70.4-0.70.6-0.4-0.90.30.4
Latency to leave start box in cocaine runway0.71.02.3-1.00.91.1-0.80.9-0.9-0.90.91.5
Latency to leave start box in cocaine runway, F0.20.20.6-0.30.40.6-0.20.4-0.5-0.30.50.8
Latency to leave start box in cocaine runway, M0.70.61.4-1.20.60.6-0.90.6-0.5-0.90.41.2
Std. dev. time between licks in bursts0.40.81.61.2-0.9-0.71.1-0.90.61.1-0.6-0.3
Total sessions with >9 infusions1.72.24.1-1.51.81.0-1.61.7-1.3-2.01.30.3
Short access day 1 total inactive lever presses3.97.89.7-2.13.12.8-2.53.1-3.0-2.82.92.7
Short access day 10 total inactive lever presses0.42.73.7-1.51.61.9-1.81.7-1.9-1.11.91.2
Short access day 1 total infusions3.06.07.7-2.22.82.2-2.52.7-2.5-2.52.62.1
Short access day 10 total infusions2.43.96.3-2.02.41.7-1.92.2-1.8-2.51.71.3
Short access total infusions1.82.64.2-1.52.01.2-1.61.9-1.5-2.11.50.9
Short access day 1 locomotion2.84.66.4-2.32.21.9-2.52.2-2.1-1.92.11.9
Short access day 10 total locomotion0.62.23.7-1.81.61.5-1.91.5-1.5-1.51.3-0.3
Short access total locomotion0.50.81.7-0.91.10.5-1.00.9-0.6-1.30.6-0.3
One hour access (0.3 mA shock)2.42.94.4-1.91.81.5-1.81.7-1.4-2.11.31.6
Compulsive drug intake1.62.33.01.7-1.6-1.31.7-1.41.31.6-1.2-1.6
One hour access (shock baseline)2.05.27.5-2.62.42.0-2.42.2-1.9-2.71.72.4
Social response proportion0.10.10.20.2-0.0-0.30.4-0.10.4-0.4-0.4-0.3
Social responses0.20.21.00.5-0.4-0.20.4-0.50.30.2-0.4-1.0
Social time0.20.31.30.2-0.1-0.40.3-0.30.4-0.3-0.6-1.1
Soleus weight4.011.714.0-3.73.43.7-3.33.5-3.6-2.93.53.1
Bone: stiffness0.00.00.10.2-0.20.2-0.2-0.3-0.10.4-0.2-0.3
Tibialis anterior weight2.69.111.3-3.32.63.4-3.12.9-3.3-1.73.33.2
Time to tail flick, vehicle, before self-admin0.20.31.00.2-0.5-1.00.3-0.50.80.0-0.6-0.2
Time to tail flick, vehicle, after self-admin1.73.65.01.8-2.2-2.21.8-1.92.22.0-1.6-0.8
Time to tail flick, test, before self-admin0.10.10.5-0.20.40.0-0.30.3-0.3-0.50.30.7
Time to tail flick, test, after self-admin0.60.72.0-1.10.80.4-0.80.8-0.4-1.40.50.6
Delta time to tail flick, vehicle, before/after SA0.40.41.50.6-0.8-0.40.6-0.50.41.2-0.1-0.1
Delta time to tail flick, test, before/after SA1.62.03.0-1.61.51.5-1.31.5-1.3-1.71.20.8
Tibia length2.46.610.62.6-2.1-2.72.8-2.42.61.4-2.8-3.3
Ambulatory time before self-admin0.10.20.4-0.60.30.4-0.30.1-0.1-0.6-0.30.6
Ambulatory time after self-admin0.81.32.41.1-1.0-0.91.3-1.21.20.7-1.6-0.8
Bone: tissue strength0.60.61.00.5-0.9-0.80.7-1.01.00.8-1.00.2
Total heroin consumption2.32.83.5-1.41.71.7-1.61.9-1.8-1.41.81.5
Bone: trabecular number2.44.45.6-1.92.12.4-1.52.3-2.3-1.92.32.2
Bone: trabecular spacing2.23.36.91.5-1.4-1.91.3-1.91.90.9-2.2-2.6
Bone: trabecular thickness0.40.61.3-0.30.70.9-0.01.0-0.9-0.71.10.6
Bone: trabecular tissue density0.30.51.0-0.50.70.8-0.80.6-0.7-0.60.51.0
Water consumed over 24 hours0.20.31.80.1-0.10.6-0.10.1-0.40.70.51.3
Number of responses in last shaping day0.60.81.3-0.61.10.5-0.61.0-0.7-1.00.71.1