Hub : Genes

Dpf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Dpf1 0.24 0.16 3.2e-15 0.13 0.14 0.14 0.14 9.8e-14 1.3e-15 1.6e-15 4.3e-15
2 NAcc gene expression Dpf1 0.14 0.08 1.2e-13 0.13 0.12 0.12 0.12 4.2e-15 4.0e-14 7.5e-14 6.5e-14
3 BLA gene expression Dpf1 0.52 0.22 4.7e-10 0.13 0.15 0.14 0.16 1.2e-07 1.6e-08 4.6e-08 3.6e-09
4 Brain gene expression Dpf1 0.26 0.03 0.0e+00 0.21 0.2 0.19 0.2 5.9e-19 2.4e-18 3.1e-17 2.9e-18
5 RMTg intron excision ratio chr1_84609784_84610001 0.15 0.11 9.3e-04 0.12 0.04 0.09 0.09 4.1e-04 2.5e-02 1.7e-03 2.3e-03
6 RMTg intron excision ratio chr1_84610090_84611337 0.1 0.08 7.2e-03 0.08 0.01 0.03 0.07 4.2e-03 1.6e-01 5.1e-02 7.8e-03
7 BLA intron excision ratio chr1_84609784_84611337 0.05 0.04 2.9e-03 0.01 0.01 -0 0 1.2e-01 8.2e-02 5.1e-01 3.1e-01
8 OFC gene expression Dpf1 0.48 0.2 1.5e-05 0.15 -0.01 0.13 0.02 2.0e-04 8.7e-01 6.5e-04 1.2e-01
9 PL intron excision ratio chr1_84609784_84611337 0.04 0.03 1.8e-05 0.04 0.04 0.04 0.04 3.5e-05 1.7e-05 6.9e-05 2.0e-05
10 NAcc isoform ratio XM_039088425.1 0.02 0.02 9.3e-03 0.01 0.01 0 0 4.3e-02 4.7e-02 1.7e-01 7.3e-02
11 NAcc intron excision ratio chr1_84609784_84611337 0.09 0.06 7.6e-06 0.04 0.04 0.04 0.04 8.9e-06 2.4e-05 9.5e-06 2.1e-05
12 Brain intron excision ratio chr1_84610090_84611337 0.02 0.02 8.4e-03 0.02 0.01 0.01 0.01 1.1e-02 1.6e-02 1.7e-02 2.4e-02
13 Brain intron excision ratio chr1_84609784_84611337 0.09 0.07 1.1e-05 0.05 0.06 0.04 0.05 1.3e-05 7.3e-06 8.7e-05 2.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.10.10.2-0.00.2-0.30.4-0.20.20.20.30.3-0.2-0.40.40.2
Area under the delay curve0.80.81.81.3-1.31.0-1.3-1.01.0-0.8-1.0-0.40.5-0.10.10.2
BMI with tail0.30.91.6-1.31.3-1.01.20.9-0.91.11.00.8-0.8-0.60.40.4
BMI without tail0.10.30.50.4-0.40.5-0.3-0.70.7-0.5-0.4-0.60.70.5-0.7-0.7
Body weight2.410.212.42.9-3.03.3-2.9-3.03.0-3.3-2.7-3.53.53.3-3.4-3.5
Weight adjusted by age0.20.30.5-0.60.7-0.60.70.4-0.40.50.60.5-0.3-0.40.50.3
Bone surface0.30.61.30.9-0.70.6-0.5-1.11.1-0.7-0.6-0.70.80.5-0.5-0.7
Bone volume0.30.50.90.8-0.70.6-0.5-1.01.0-0.7-0.6-0.60.70.5-0.5-0.7
Breakpoint value in progressive ratio session3.23.55.62.4-2.41.9-2.3-2.32.3-2.0-1.6-1.61.21.3-1.2-1.0
Number of licking bursts2.73.24.2-2.01.8-1.81.72.0-2.01.91.71.8-1.8-1.51.61.6
Context. condit. distance diff. score0.00.10.1-0.10.2-0.30.10.0-0.00.20.30.2-0.3-0.30.30.3
Locomotion velocity, session 11.61.83.1-1.01.1-1.31.00.9-0.91.41.01.6-1.7-1.71.51.8
Locomotion distance, session 10.81.01.60.9-0.91.2-1.2-0.70.7-1.0-1.3-1.01.01.0-1.1-1.0
Locomotion velocity, session 20.40.50.9-0.71.0-0.80.90.4-0.40.71.00.6-0.5-0.70.50.5
Locomotion distance, session 21.01.32.5-1.41.6-1.11.21.4-1.41.21.21.0-0.9-0.80.70.6
Locomotion velocity, session 30.40.51.3-0.91.1-0.90.90.6-0.60.70.90.5-0.6-0.30.30.4
Locomotion distance, session 34.65.17.21.9-1.82.2-1.9-2.02.0-2.3-1.9-2.52.52.6-2.6-2.7
Stereotopy head waving bouts, day 31.21.52.8-1.41.6-1.51.71.1-1.11.11.70.9-1.0-0.50.60.6
Stereotopy head waving duration, day 32.93.55.0-1.82.1-2.22.11.5-1.51.82.21.8-1.9-1.71.71.7
Locomotion velocity, session 70.00.00.10.2-0.00.00.0-0.40.4-0.10.1-0.10.1-0.1-0.0-0.1
Locomotion distance, session 70.00.10.10.2-0.10.2-0.2-0.20.2-0.2-0.2-0.30.30.3-0.3-0.3
Stereotopy head waving bouts, day 70.30.30.8-0.80.8-0.50.70.8-0.80.50.90.3-0.3-0.10.20.0
Stereotopy head waving duration, day 71.41.82.5-1.51.5-1.41.41.5-1.51.31.61.2-1.2-1.01.00.9
Locomotion velocity, session 84.04.86.0-2.42.4-2.42.32.2-2.22.32.42.1-2.1-1.91.91.9
Locomotion distance, session 80.40.60.9-0.91.0-0.80.60.9-0.90.80.80.8-0.7-0.70.70.7
Degree of sensitization distance2.32.34.0-1.01.2-1.51.21.0-1.01.51.31.8-1.8-1.92.02.0
Degree of sensitization stereotypy0.30.31.0-0.80.6-0.30.51.0-1.00.40.60.1-0.10.0-0.0-0.1
Conditioned locomotion0.30.30.8-0.60.6-0.20.60.5-0.5-0.10.5-0.50.40.8-0.8-0.9
Cocaine response after cond. corrected0.20.20.60.1-0.30.4-0.3-0.10.1-0.4-0.1-0.60.60.7-0.7-0.8
Cocaine response after cond. not corrected0.30.31.1-0.0-0.00.3-0.1-0.00.0-0.40.1-0.70.70.9-0.9-1.0
Cocaine response before conditioning0.81.02.50.5-0.20.7-0.4-0.80.8-0.9-0.4-1.21.21.6-1.5-1.5
Saline control response0.30.40.50.5-0.70.7-0.7-0.30.3-0.6-0.7-0.70.70.7-0.7-0.7
Bone: connectivity density0.30.51.2-0.30.6-0.80.60.0-0.00.70.60.9-0.7-1.11.10.9
Bone: cortical apparent density2.33.13.5-1.81.8-1.81.71.8-1.81.91.61.8-1.8-1.61.61.7
Bone: cortical area1.82.63.51.4-1.61.6-1.4-1.31.3-1.7-1.5-1.81.71.9-1.9-1.9
Bone: cortical porosity1.92.13.5-1.81.9-1.61.81.7-1.71.41.91.1-1.0-0.80.80.6
Bone: cortical porosity2.22.43.9-1.92.0-1.71.91.8-1.81.52.01.1-1.1-0.80.80.6
Bone: cortical thickness0.61.01.70.7-0.81.0-0.7-0.60.6-1.0-0.9-1.21.11.3-1.3-1.3
Bone: cortical thickness0.60.71.4-1.11.1-0.91.21.1-1.10.81.10.4-0.4-0.10.20.1
Bone: cortical tissue density2.83.64.1-2.01.9-2.01.91.9-1.92.01.82.0-2.0-1.81.81.8
Condit. Reinf. active minus inactive responses0.20.30.5-0.50.5-0.50.50.3-0.30.60.40.6-0.7-0.40.60.6
Condit. Reinf. active-inactive response ratio0.20.20.4-0.40.4-0.50.50.2-0.20.40.50.4-0.6-0.30.50.5
Condit. Reinf. active responses1.41.72.3-1.51.4-1.31.41.4-1.41.51.21.3-1.3-1.11.21.1
Condit. Reinf. inactive responses1.11.32.1-1.41.2-1.01.11.5-1.51.30.91.1-0.9-1.00.90.7
Incentive salience index mean0.10.10.1-0.40.4-0.20.30.1-0.10.30.30.2-0.3-0.10.20.1
Condit. Reinf. lever presses0.10.10.20.2-0.20.4-0.3-0.50.5-0.2-0.3-0.30.40.3-0.3-0.4
Condit. Reinf. active minus inactive responses3.84.75.81.9-1.82.2-1.9-2.22.2-2.2-2.1-2.32.22.4-2.4-2.3
Condit. Reinf. active-inactive response ratio1.51.63.70.5-0.71.2-0.8-0.60.6-1.2-0.9-1.61.41.9-1.9-1.8
Condit. Reinf. active responses4.76.67.12.5-2.32.6-2.4-2.72.7-2.7-2.5-2.72.62.7-2.6-2.5
Condit. Reinf. inactive responses2.53.14.52.1-1.91.8-1.9-2.02.0-1.8-2.0-1.51.51.3-1.2-1.2
Condit. Reinf. lever presses8.611.714.03.7-3.73.7-3.7-3.53.5-3.6-3.6-3.33.13.1-3.1-2.8
Condit. Reinf. lever reinforcers received5.47.58.72.6-2.52.8-2.5-2.72.7-2.8-2.7-2.92.82.9-2.9-2.8
Conditioned reinforcement - actives0.20.20.6-0.10.00.30.10.6-0.6-0.2-0.3-0.40.80.5-0.5-0.6
Conditioned reinforcement - inactives1.61.82.61.2-1.31.5-1.4-0.60.6-1.5-1.4-1.61.51.6-1.6-1.6
Conditioned locomotion1.92.33.5-1.71.9-1.61.91.7-1.71.51.51.3-1.1-1.21.21.0
Patch foraging indifference point 0 sec0.20.30.50.3-0.40.5-0.30.0-0.0-0.5-0.6-0.60.60.7-0.6-0.6
Patch foraging indifference point AUC0.50.51.0-0.91.0-0.81.00.7-0.70.80.50.7-0.6-0.60.50.5
Delay disc. indifference point, 0s delay0.91.01.71.2-1.21.2-1.3-0.90.9-1.0-1.2-0.81.10.5-0.6-0.5
Delay disc. indifference point, 16s delay2.62.74.82.0-2.21.9-2.0-1.71.7-1.6-1.8-1.31.50.8-0.9-0.8
Delay disc. indifference point, 2s delay0.80.92.31.5-1.41.0-1.5-0.90.9-0.9-1.2-0.30.3-0.30.30.4
Delay disc. indifference point, 24s delay2.32.23.01.7-1.71.6-1.7-1.71.7-1.5-1.6-1.31.31.0-1.1-1.0
Delay disc. indifference point, 4s delay0.20.20.60.6-0.70.6-0.7-0.40.4-0.4-0.5-0.30.40.1-0.2-0.1
Delay disc. indifference point, 8s delay0.40.41.40.4-0.3-0.2-0.2-0.30.30.30.20.7-0.7-1.11.11.2
Indifference point function ln k0.50.71.01.0-0.90.9-0.9-1.01.0-0.9-0.8-0.80.70.7-0.7-0.6
Indifference point function log k0.50.71.01.0-0.90.9-0.9-1.01.0-0.9-0.8-0.80.70.7-0.7-0.6
Patch foraging total patch changes 0 sec0.30.40.70.5-0.60.7-0.6-0.20.2-0.7-0.8-0.70.80.8-0.7-0.7
Patch foraging total patch changes 12 sec0.20.30.50.3-0.20.5-0.2-0.30.3-0.5-0.6-0.60.70.7-0.6-0.7
Patch foraging total patch changes 18 sec0.20.30.6-0.60.7-0.50.70.8-0.80.50.10.4-0.2-0.20.20.2
Patch foraging total patch changes 24 sec0.70.92.00.9-0.91.1-1.0-0.80.8-1.0-1.4-0.91.00.8-0.8-0.8
Patch foraging total patch changes 6 sec0.10.10.2-0.10.10.10.10.4-0.4-0.1-0.3-0.30.40.4-0.4-0.4
Patch foraging time to switch 0 sec0.71.11.8-0.70.9-1.10.90.5-0.51.01.11.2-1.2-1.31.41.3
Patch foraging water rate 0 sec0.71.11.9-1.21.0-1.01.01.4-1.41.01.10.9-1.0-0.80.70.7
Patch foraging water rate 12 sec0.71.11.80.9-1.21.2-1.1-0.50.5-1.1-1.1-1.20.91.1-1.4-1.0
Patch foraging water rate 18 sec0.40.51.4-0.2-0.1-0.4-0.10.6-0.60.50.70.8-1.1-1.01.01.2
Patch foraging water rate 24 sec0.20.30.90.3-0.60.5-0.60.1-0.1-0.5-0.1-0.70.30.8-0.9-0.6
Patch foraging water rate 6 sec0.30.41.10.8-0.80.6-0.8-1.01.0-0.6-0.6-0.40.20.3-0.3-0.2
Seeking ratio, delayed vs. immediate footshock1.41.61.91.3-1.31.2-1.3-1.31.3-1.4-1.4-1.30.91.3-1.2-1.2
Distance traveled before self-admin1.41.52.90.9-1.21.3-1.1-0.60.6-1.3-1.0-1.41.11.6-1.7-1.4
Distance traveled after self-admin5.46.17.32.5-2.52.7-2.5-2.12.1-2.6-2.5-2.52.52.5-2.6-2.3
Extensor digitorum longus weight0.20.80.9-0.90.9-0.90.80.8-0.80.90.80.9-0.9-0.90.90.9
Bone: elastic displacement0.00.00.1-0.10.1-0.10.10.3-0.30.10.10.2-0.2-0.20.20.3
Bone: elastic work1.82.43.31.4-1.41.6-1.3-1.41.4-1.6-1.3-1.71.61.8-1.8-1.7
Bone: endosteal estimation1.53.24.21.9-1.91.9-1.8-2.12.1-1.8-1.8-1.71.81.5-1.5-1.6
Bone: endosteal perimeter1.63.44.62.1-2.12.0-2.0-2.12.1-1.9-2.0-1.61.71.3-1.3-1.4
Epididymis fat weight0.00.00.0-0.10.2-0.10.1-0.00.00.2-0.00.2-0.0-0.20.10.1
Delta time in closed arm before/after self-admin1.00.91.71.1-0.91.0-0.9-1.31.3-0.9-0.9-0.81.10.5-0.7-0.7
Delta time in open arm before/after self-admin0.50.41.1-1.00.7-0.60.71.0-1.00.60.40.3-0.60.00.10.1
Diff in mean of infusions in LGA sessions0.20.30.70.6-0.70.5-0.9-0.60.6-0.5-0.3-0.40.20.5-0.3-0.1
Delay discount exponential model param0.80.81.8-1.31.3-1.01.31.0-1.00.81.00.4-0.50.1-0.0-0.1
Extinction: sum of active levers before priming2.02.04.21.5-1.41.4-1.3-2.12.1-1.3-1.4-1.21.21.1-1.0-1.1
Active lever presses in extinction session 61.51.54.01.6-1.21.1-1.1-2.02.0-1.1-1.1-0.80.90.5-0.5-0.4
Bone: final force1.52.33.11.3-1.41.5-1.3-1.41.4-1.6-1.4-1.71.71.8-1.7-1.7
Bone: final moment2.13.54.71.6-1.71.9-1.5-1.61.6-1.9-1.7-2.12.02.2-2.1-2.1
Food consumed during 24 hour testing period0.50.61.10.9-0.80.9-0.9-0.90.9-0.8-1.0-0.70.60.6-0.5-0.5
Glucose0.20.40.7-0.50.6-0.50.50.5-0.50.70.60.7-0.6-0.80.60.6
Heart weight0.40.61.20.4-0.40.6-0.3-0.70.7-0.8-0.5-1.00.91.1-1.1-1.1
Delay discount hyperbolic model param0.60.71.6-1.21.3-0.91.30.9-0.90.71.00.3-0.40.2-0.1-0.3
Intermittent access intake day 1-15 change1.71.63.01.3-1.21.4-1.3-1.21.2-1.3-1.7-1.21.41.0-1.0-1.2
Intermittent access intake escalation1.31.32.51.2-1.11.2-1.1-1.21.2-1.2-1.6-1.11.10.8-0.8-1.0
Intermittent access intake escalation 23.02.93.71.5-1.61.9-1.7-1.41.4-1.8-1.9-1.81.81.7-1.7-1.8
Intermitt. access day 1 inactive lever presses1.71.84.91.7-1.51.2-1.3-2.22.2-1.2-1.4-0.80.80.4-0.4-0.5
Intermitt. access day 15 inactive lever presses0.60.71.31.1-1.10.9-1.0-1.11.1-0.8-0.7-0.50.70.3-0.3-0.2
Intermitt. access escalation Index0.10.10.10.1-0.30.1-0.30.4-0.4-0.20.3-0.3-0.30.4-0.4-0.2
Intermittent access day 1 total infusions0.81.03.0-1.30.9-0.81.01.7-1.70.71.10.4-0.80.1-0.10.1
Intermittent access day 15 total infusions0.40.51.00.4-0.60.7-0.40.2-0.2-0.7-0.7-0.90.61.0-1.0-0.9
Intermittent access terminal intake (last 3 days)0.80.81.80.4-0.70.9-0.70.3-0.3-0.9-0.7-1.11.01.3-1.3-1.3
Intermittent access total infusions0.30.30.7-0.2-0.20.3-0.00.7-0.7-0.3-0.1-0.60.30.8-0.8-0.7
Intermittent access day 1 locomotion0.40.41.0-0.90.8-0.60.91.0-1.00.60.70.3-0.30.0-0.0-0.1
Intermittent access day 15 total locomotion0.10.10.2-0.30.3-0.30.30.5-0.50.20.10.2-0.2-0.20.20.1
Intermittent access total locomotion0.70.81.5-1.11.1-0.91.21.1-1.11.00.80.8-0.6-0.70.70.5
Intermittent access standard deviation6.16.58.42.7-2.82.8-2.7-2.52.5-2.7-2.9-2.52.42.2-2.2-2.2
Left kidney weight1.95.59.71.6-1.62.2-1.6-2.12.1-2.3-1.7-2.72.73.0-3.0-3.1
Right kidney weight3.910.912.63.0-3.03.3-3.0-3.53.5-3.3-2.7-3.53.43.6-3.5-3.5
Cocaine induced anxiety0.30.31.00.8-0.70.4-0.5-1.01.0-0.4-0.1-0.10.50.1-0.10.2
Post-drug Anxiety0.10.20.80.3-0.2-0.1-0.1-0.10.10.20.30.5-0.1-0.60.60.9
Baseline Anxiety0.70.82.0-1.11.1-0.90.91.4-1.40.80.60.5-0.6-0.30.30.2
Tail length5.717.119.64.2-4.44.4-4.2-3.93.9-4.4-4.1-4.24.33.8-3.9-3.9
Length with tail8.129.733.75.6-5.75.7-5.5-5.25.2-5.8-5.1-5.65.65.2-5.1-5.2
Length without tail3.68.09.12.9-3.03.0-2.9-2.72.7-3.0-2.5-2.92.82.8-2.7-2.7
Times rat made contact with spout1.01.12.0-1.31.2-1.01.21.4-1.41.01.20.8-0.7-0.60.60.5
Lifetime Intake0.20.31.0-0.60.4-0.30.61.0-1.00.20.4-0.0-0.20.3-0.3-0.2
Liver weight, left0.50.71.8-1.11.0-0.81.11.3-1.30.70.90.4-0.2-0.20.30.0
Liver weight, right0.10.10.4-0.30.3-0.10.30.6-0.60.10.0-0.00.10.2-0.2-0.2
Locomotor activity0.61.01.8-1.11.2-1.11.20.9-0.91.01.30.9-0.9-0.90.70.6
Locomotor testing distance0.81.41.8-1.21.3-1.31.30.8-0.81.31.31.2-1.3-1.21.11.2
Locomotor testing rearing2.03.14.2-2.01.9-1.92.02.0-2.01.82.01.5-1.7-1.21.21.3
Locomotion in novel chamber0.20.20.7-0.00.1-0.40.1-0.00.00.40.20.6-0.7-0.80.70.7
Locomotion in novel chamber post-restriction0.40.51.11.0-0.80.5-0.8-1.01.0-0.6-0.8-0.3-0.20.1-0.10.0
Fecal boli incidents, locomotor time 12.12.34.0-0.91.1-1.51.11.1-1.11.51.51.8-1.7-2.02.02.0
Change in fecal boli incidents, locomotor task0.20.10.40.2-0.20.2-0.1-0.60.6-0.3-0.2-0.40.30.4-0.4-0.5
Time >=10cm from walls, locomotor time 10.00.00.1-0.10.1-0.20.1-0.20.20.10.20.1-0.1-0.10.20.1
Bouts of movement, locomotor time 11.31.53.51.8-1.91.4-1.9-1.01.0-1.3-1.3-0.80.80.3-0.4-0.2
Total resting periods, locomotor time 11.21.43.21.8-1.81.3-1.8-1.11.1-1.3-1.3-0.70.60.2-0.3-0.1
Rest time, locomotor task time 10.00.00.1-0.20.1-0.20.20.2-0.20.20.10.3-0.2-0.30.20.3
Distance moved, locomotor task time 10.10.10.3-0.40.4-0.20.40.4-0.40.00.3-0.20.30.4-0.4-0.5
Vertical activity count, locomotor time 10.80.91.60.7-0.60.7-0.6-1.01.0-0.9-0.7-1.11.11.0-1.0-1.3
Time >=10cm from walls, locomotor time 20.10.10.3-0.60.3-0.10.30.5-0.50.20.2-0.00.10.3-0.1-0.2
Bouts of movement, locomotor time 20.20.20.50.6-0.50.2-0.5-0.20.2-0.2-0.30.20.1-0.60.60.7
Total resting periods, locomotor time 20.10.10.50.4-0.30.1-0.3-0.10.1-0.0-0.10.3-0.0-0.60.60.7
Rest time, locomotor task time 20.10.10.4-0.1-0.00.2-0.10.2-0.2-0.2-0.1-0.40.20.5-0.6-0.6
Distance moved, locomotor task time 20.20.20.5-0.70.5-0.40.60.7-0.70.50.50.3-0.1-0.10.20.1
Vertical activity count, locomotor time 20.30.30.60.7-0.70.6-0.6-0.80.8-0.6-0.6-0.50.60.3-0.3-0.4
Light reinforcement 10.10.30.6-0.50.5-0.40.50.8-0.80.50.10.5-0.4-0.50.40.5
Light reinforcement 25.37.110.3-2.12.4-2.82.41.8-1.82.72.53.0-3.0-3.23.23.1
Bone: marrow area1.53.34.31.9-1.91.9-1.8-2.12.1-1.8-1.8-1.71.81.6-1.5-1.6
Bone: maximum diameter1.32.42.91.4-1.41.6-1.4-1.61.6-1.6-1.5-1.71.71.6-1.6-1.7
Bone: maximum force2.74.65.32.0-2.12.2-2.0-2.02.0-2.2-2.1-2.32.22.3-2.3-2.2
Bone: maximum moment3.56.07.02.2-2.42.5-2.2-2.22.2-2.5-2.4-2.62.52.6-2.6-2.6
Mean time between licks in bursts0.10.10.30.1-0.20.1-0.1-0.30.3-0.3-0.1-0.40.40.6-0.2-0.4
Mean num. licks in bursts0.70.81.30.9-0.70.9-0.7-0.90.9-1.0-0.7-1.01.10.9-1.0-1.1
Cd content in liver0.20.20.5-0.20.2-0.40.20.2-0.20.40.20.6-0.6-0.60.70.7
Co content in liver1.51.82.5-1.11.3-1.51.30.7-0.71.41.41.5-1.6-1.51.61.5
Cu content in liver0.80.91.70.7-0.91.0-0.8-0.40.4-1.0-0.8-1.21.11.3-1.2-1.2
Fe content in liver0.20.20.6-0.00.1-0.20.00.1-0.10.40.20.6-0.5-0.80.70.7
K content in liver0.30.30.80.1-0.10.4-0.2-0.30.3-0.5-0.2-0.70.70.9-0.9-0.9
Mg content in liver0.20.20.5-0.70.6-0.40.60.7-0.70.30.6-0.00.00.4-0.2-0.3
Mn content in liver0.70.81.4-1.21.1-0.51.01.2-1.20.30.9-0.30.30.9-0.9-1.0
Na content in liver4.34.56.41.7-1.72.1-1.8-1.91.9-2.2-1.8-2.42.42.4-2.5-2.5
Rb content in liver0.00.00.00.1-0.20.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.00.0
Se content in liver6.27.611.0-3.33.2-2.93.13.3-3.32.83.22.3-2.3-1.91.81.7
Sr content in liver0.90.81.1-1.01.0-1.01.00.8-0.81.01.00.9-1.0-0.80.80.8
Zn content in liver0.30.30.4-0.50.5-0.60.60.3-0.30.60.50.6-0.6-0.60.50.6
Bone: minimum diameter5.29.611.12.8-3.03.2-2.9-2.92.9-3.2-3.0-3.33.23.3-3.3-3.3
Time in familiar zone, hab. session 10.30.30.50.6-0.40.6-0.7-0.50.5-0.6-0.6-0.50.60.4-0.5-0.5
Time in novel zone, hab. session 10.40.30.9-0.70.5-0.60.51.0-1.00.50.70.4-0.5-0.20.30.3
Total zone transitions, hab. session 10.30.50.80.4-0.40.8-0.8-0.30.3-0.6-0.8-0.70.80.8-0.9-0.9
Total locomotion distance, hab. session 13.24.66.62.1-2.22.4-2.5-1.71.7-2.2-2.6-2.12.22.0-2.0-2.0
Locomotion velocity, hab. session 11.62.23.71.5-1.51.7-1.8-1.31.3-1.5-1.9-1.41.41.3-1.3-1.2
Time in familiar zone, hab. session 21.31.42.71.6-1.31.2-1.3-1.61.6-1.2-1.3-0.90.80.6-0.5-0.5
Time in novel zone, hab. session 21.01.01.9-1.20.9-1.01.01.4-1.41.01.00.9-0.8-0.70.70.7
Total zone transitions, hab. session 20.81.12.6-1.51.5-0.81.11.6-1.61.00.90.5-0.5-0.10.20.0
Total locomotion distance, hab. session 20.20.30.70.2-0.20.6-0.40.0-0.0-0.5-0.6-0.60.60.8-0.6-0.7
Locomotion velocity, hab. session 20.10.20.6-0.10.10.3-0.10.2-0.2-0.3-0.3-0.50.50.8-0.6-0.7
Novel to familiar place preference ratio0.90.91.80.6-0.81.1-0.8-0.50.5-0.9-1.0-1.11.11.0-1.3-1.2
Novelty place preference0.80.81.70.5-0.81.0-0.7-0.40.4-0.8-1.0-1.01.11.0-1.3-1.1
Time in novel zone, NPP test0.40.41.10.3-0.60.7-0.5-0.20.2-0.6-0.7-0.70.80.7-1.1-0.9
Total zone transitions, NPP test0.10.20.3-0.40.5-0.30.20.5-0.50.50.10.5-0.4-0.60.60.4
Total locomotion distance, NPP test2.23.04.42.0-1.81.9-2.0-1.71.7-1.8-2.1-1.61.71.4-1.4-1.4
Locomotion velocity, NPP test2.63.75.22.1-1.92.1-2.1-1.81.8-2.0-2.3-1.81.91.6-1.6-1.6
Intraocular pressure0.10.10.30.4-0.50.2-0.6-0.10.1-0.1-0.30.2-0.1-0.30.30.3
Delta distance traveled before/after self-admin1.81.93.41.8-1.51.4-1.6-1.81.8-1.4-1.7-1.01.20.6-0.6-0.6
Delta ambulatory time before/after self-admin1.81.92.71.6-1.41.5-1.5-1.61.6-1.4-1.5-1.31.41.0-1.0-1.1
Parametrial fat weight0.81.62.7-1.41.6-1.51.61.1-1.11.31.41.2-1.1-1.01.00.9
Pavlov. Cond. lever latency0.10.10.30.4-0.50.0-0.3-0.40.4-0.1-0.20.2-0.3-0.40.40.6
Pavlov. Cond. magazine entry latency0.20.20.6-0.40.2-0.20.20.8-0.80.40.30.4-0.5-0.40.40.5
Pavlov. Cond. change in total contacts0.00.00.0-0.20.00.0-0.00.2-0.20.10.00.0-0.00.00.0-0.0
Pavlov. Cond. index score0.20.20.6-0.70.6-0.30.50.8-0.80.40.50.1-0.10.1-0.1-0.2
Pavlov. Cond. latency score0.10.10.2-0.40.4-0.10.30.4-0.40.20.3-0.10.10.2-0.2-0.3
Pavlov. Cond. lever contacts0.40.51.10.3-0.30.7-0.4-0.30.3-0.6-0.5-0.80.90.9-0.9-1.0
Pavlov. Cond. magazine entry number0.20.20.80.5-0.30.3-0.3-0.90.9-0.4-0.4-0.30.40.2-0.2-0.3
Pavlov. Cond. intertrial magazine entries0.30.30.7-0.80.8-0.70.80.4-0.40.60.80.5-0.5-0.30.20.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.7-0.70.5-0.20.50.9-0.90.30.5-0.00.10.3-0.3-0.4
Pavlov. Cond. response bias0.00.10.1-0.10.00.2-0.10.4-0.4-0.1-0.1-0.20.20.3-0.3-0.3
Pavlov. Cond. lever latency4.45.97.6-2.72.6-2.62.62.8-2.82.52.52.3-2.1-2.12.11.9
Pavlov. Cond. magazine entry latency2.73.24.32.1-1.91.9-1.9-2.12.1-1.8-1.9-1.61.51.3-1.4-1.2
Pavlov. Cond. change in total contacts8.211.314.33.7-3.53.5-3.6-3.83.8-3.5-3.4-3.23.02.9-2.9-2.7
Pavlov. Cond. index score4.55.77.72.8-2.72.6-2.7-2.82.8-2.5-2.5-2.12.01.9-1.9-1.7
Pavlov. Cond. latency score4.35.37.22.6-2.52.4-2.5-2.72.7-2.3-2.5-2.11.91.8-1.8-1.6
Pavlov. Cond. lever contacts4.25.77.02.6-2.62.5-2.6-2.62.6-2.5-2.4-2.22.12.0-2.0-1.8
Pavlov. Cond. magazine entry number2.73.45.5-2.32.2-2.02.22.3-2.31.82.11.4-1.3-1.01.10.9
Pavlov. Cond. intertrial magazine entries1.72.23.2-1.71.7-1.61.61.8-1.81.51.61.3-1.3-0.91.00.9
Pavlov. Cond. lever-magazine prob. diff.4.65.97.42.7-2.62.6-2.6-2.72.7-2.5-2.6-2.22.22.0-2.0-1.8
Pavlov. Cond. response bias4.76.48.12.8-2.82.7-2.8-2.82.8-2.6-2.6-2.42.22.2-2.2-2.0
Time in closed arm before self-admin0.50.62.1-0.90.3-0.60.31.4-1.40.51.10.4-0.8-0.10.20.4
Time in closed arm after self-admin0.40.41.10.9-1.00.6-1.0-0.70.7-0.7-0.1-0.50.40.3-0.3-0.2
Time in open arm before self-admin1.82.04.21.4-1.01.3-1.1-2.02.0-1.3-1.3-1.31.51.1-1.2-1.3
Time in open arm after self-admin0.50.51.70.00.00.50.0-0.60.6-0.5-0.5-0.90.81.1-1.1-1.3
Bone: periosteal estimation2.14.34.72.0-2.12.1-1.9-2.12.1-2.1-2.0-2.22.12.1-2.1-2.1
Bone: periosteal perimeter2.13.54.11.9-2.02.0-1.9-2.02.0-1.9-1.9-1.91.81.7-1.7-1.7
Bone: post-yield work1.31.82.81.6-1.61.4-1.6-1.61.6-1.3-1.7-1.11.10.9-0.8-0.8
Progressive ratio test 1 active lever presses0.70.81.90.5-0.60.7-0.5-0.30.3-0.9-0.5-1.20.51.3-1.3-1.4
Progressive ratio test 1 breakpoint1.11.22.50.8-0.80.9-0.8-0.70.7-1.2-0.7-1.40.71.6-1.6-1.6
Progressive ratio test 1 inactive lever presses0.50.61.01.0-1.00.9-0.9-0.60.6-0.8-0.8-0.70.70.5-0.5-0.5
Progressive ratio test 2 active lever presses0.40.40.60.6-0.70.8-0.7-0.10.1-0.7-0.7-0.80.50.8-0.8-0.7
Progressive ratio test 2 breakpoint0.40.40.70.5-0.70.7-0.70.0-0.0-0.7-0.6-0.70.50.8-0.8-0.8
Progressive ratio test 2 inactive lever presses3.43.95.72.2-2.42.3-2.3-1.61.6-2.1-2.3-1.91.71.7-1.7-1.6
Incentive Sensitization - Responses0.10.10.30.4-0.40.4-0.5-0.00.0-0.2-0.4-0.10.0-0.00.00.1
Incentive Sensitization - Breakpoint0.10.10.10.2-0.30.3-0.40.1-0.1-0.0-0.30.1-0.1-0.20.20.3
Sum of active levers in priming session hrs 5-60.10.10.20.20.2-0.0-0.0-0.50.5-0.20.1-0.20.10.2-0.2-0.2
Progressive ratio0.20.20.80.10.2-0.20.1-0.30.30.4-0.00.6-0.1-0.80.90.8
Food seeking constrained by brief footshock3.54.35.32.2-2.22.2-2.1-2.12.1-2.1-2.3-2.02.02.0-1.9-1.8
Seeking ratio, punishment vs. effort1.41.72.91.1-1.41.3-1.3-0.70.7-1.4-1.1-1.61.01.7-1.7-1.5
Retroperitoneal fat weight1.65.17.2-2.72.6-2.32.52.7-2.72.42.32.1-1.9-1.81.71.5
Reaction time number correct0.20.30.6-0.80.7-0.50.80.7-0.70.30.6-0.0-0.10.4-0.4-0.4
Reaction time mean minus median0.10.20.30.3-0.40.4-0.4-0.30.3-0.4-0.3-0.50.40.6-0.6-0.5
Reaction time mean minus median AUC0.20.20.50.3-0.40.4-0.4-0.20.2-0.5-0.3-0.60.50.7-0.7-0.6
Reaction time num false alarms1.21.72.1-1.41.5-1.31.41.3-1.31.31.41.2-1.1-1.21.21.0
Reaction time num false alarms AUC1.62.22.7-1.61.6-1.51.51.4-1.41.61.71.4-1.3-1.41.41.2
Reaction time trials correct on left0.20.30.6-0.80.7-0.50.80.7-0.70.30.6-0.0-0.10.4-0.4-0.4
Reaction time trials on left0.20.30.7-0.80.7-0.50.80.7-0.70.40.70.0-0.10.3-0.3-0.4
Reaction time mean0.00.10.1-0.20.1-0.30.10.1-0.10.30.40.3-0.4-0.30.20.3
Reaction time mean AUC0.20.20.5-0.50.5-0.60.40.2-0.20.60.70.5-0.6-0.50.40.5
Median of all reaction times0.20.20.4-0.40.3-0.50.30.2-0.20.50.60.6-0.6-0.60.50.5
Reaction time omissions0.40.51.2-0.70.6-0.80.70.9-0.90.61.10.5-0.6-0.50.60.4
Reaction time false alarm rate0.91.22.2-0.91.0-1.10.90.7-0.71.11.01.3-1.1-1.51.51.3
Reaction time premature initiation rate0.10.10.40.5-0.50.4-0.5-0.40.4-0.3-0.6-0.10.1-0.0-0.10.1
Reaction time premature initiations0.00.00.00.0-0.10.00.00.1-0.1-0.1-0.1-0.10.00.1-0.2-0.1
Std. dev. reaction times0.10.10.20.2-0.30.2-0.3-0.20.2-0.30.0-0.30.20.4-0.4-0.3
Reaction time trials completed0.20.30.7-0.80.7-0.50.80.7-0.70.40.70.0-0.10.3-0.3-0.4
Reaction time trials AUC0.30.51.1-1.00.9-0.71.10.8-0.80.50.90.2-0.30.2-0.2-0.3
Run reversals in cocaine runway, females0.10.10.4-0.10.2-0.30.20.0-0.00.30.20.5-0.4-0.60.60.6
Run reversals in cocaine runway, males1.41.32.7-1.21.4-1.51.40.5-0.51.21.51.1-1.6-0.80.80.9
Latency to leave start box in cocaine runway0.00.00.1-0.20.3-0.30.30.2-0.20.20.30.2-0.1-0.20.20.2
Latency to leave start box in cocaine runway, F0.50.50.7-0.60.8-0.80.80.7-0.70.70.80.7-0.8-0.60.60.7
Latency to leave start box in cocaine runway, M0.10.10.20.3-0.40.4-0.5-0.20.2-0.3-0.4-0.30.40.2-0.2-0.3
Std. dev. time between licks in bursts1.01.22.31.2-1.11.0-1.0-1.51.5-1.1-0.9-1.01.10.8-0.7-0.8
Total sessions with >9 infusions1.21.32.6-1.61.4-1.11.61.6-1.61.01.20.5-0.7-0.10.1-0.1
Short access day 1 total inactive lever presses0.80.91.81.1-1.31.1-1.1-0.80.8-1.0-1.2-0.80.80.6-0.7-0.5
Short access day 10 total inactive lever presses1.51.64.01.6-1.41.2-1.4-2.02.0-1.1-1.4-0.71.10.3-0.3-0.2
Short access day 1 total infusions0.10.20.5-0.30.3-0.10.30.3-0.3-0.20.2-0.4-0.00.7-0.7-0.7
Short access day 10 total infusions0.50.61.1-1.00.9-0.71.01.1-1.10.80.80.5-0.7-0.20.20.3
Short access total infusions0.91.01.8-1.31.2-1.01.31.3-1.30.91.20.6-0.8-0.30.30.3
Short access day 1 locomotion2.22.34.2-1.82.0-1.72.11.2-1.21.61.81.4-1.1-1.31.30.9
Short access day 10 total locomotion0.40.41.30.5-0.20.5-0.2-1.21.2-0.4-0.6-0.50.90.5-0.5-0.7
Short access total locomotion0.90.92.0-1.31.4-0.91.41.0-1.01.01.00.7-0.2-0.40.40.2
One hour access (0.3 mA shock)1.41.62.31.4-1.51.5-1.4-0.90.9-1.4-1.5-1.31.41.1-1.1-1.0
Compulsive drug intake0.40.40.70.6-0.80.8-0.8-0.30.3-0.7-0.8-0.70.80.5-0.5-0.5
One hour access (shock baseline)0.10.10.20.4-0.40.4-0.3-0.10.1-0.4-0.3-0.40.30.4-0.4-0.4
Social response proportion3.63.95.61.8-1.81.9-1.7-1.71.7-2.1-1.3-2.22.02.4-2.3-2.3
Social responses0.20.30.70.8-0.60.5-0.6-0.80.8-0.6-0.3-0.40.40.3-0.4-0.3
Social time1.41.93.41.9-1.81.5-1.8-1.61.6-1.4-1.3-1.00.90.8-0.7-0.5
Soleus weight0.51.62.9-0.80.8-1.10.81.2-1.21.20.91.5-1.4-1.71.71.7
Bone: stiffness1.42.22.41.5-1.51.6-1.4-1.41.4-1.5-1.5-1.61.51.5-1.5-1.5
Tibialis anterior weight0.00.10.2-0.40.3-0.20.30.4-0.40.20.20.10.00.0-0.0-0.1
Time to tail flick, vehicle, before self-admin0.50.51.2-1.11.1-0.51.00.9-0.90.50.50.00.40.3-0.3-0.5
Time to tail flick, vehicle, after self-admin0.40.51.00.9-0.90.6-1.0-0.70.7-0.7-0.9-0.50.20.4-0.5-0.3
Time to tail flick, test, before self-admin0.50.51.2-0.91.1-0.50.81.1-1.10.40.70.00.20.2-0.2-0.3
Time to tail flick, test, after self-admin0.30.30.7-0.60.8-0.40.60.8-0.80.30.70.10.20.1-0.0-0.1
Delta time to tail flick, vehicle, before/after SA0.50.51.11.0-1.10.6-1.0-0.80.8-0.7-0.6-0.50.10.3-0.3-0.2
Delta time to tail flick, test, before/after SA0.10.10.3-0.40.3-0.30.30.5-0.50.30.40.2-0.1-0.00.00.1
Tibia length1.95.26.12.1-2.02.2-1.9-2.42.4-2.3-1.9-2.42.42.5-2.5-2.5
Ambulatory time before self-admin0.80.91.70.8-1.01.0-1.0-0.40.4-1.0-0.7-1.00.81.2-1.3-1.0
Ambulatory time after self-admin6.77.38.82.9-2.82.9-3.0-2.62.6-2.8-2.8-2.72.62.6-2.7-2.3
Bone: tissue strength4.24.04.71.9-2.02.2-2.1-1.61.6-2.1-2.1-2.12.12.1-2.1-2.0
Total heroin consumption1.61.82.21.3-1.21.5-1.5-1.31.3-1.3-1.3-1.41.31.4-1.4-1.3
Bone: trabecular number0.20.30.90.6-0.40.4-0.3-0.90.9-0.5-0.4-0.40.50.2-0.2-0.4
Bone: trabecular spacing1.41.92.51.2-1.31.5-1.4-0.90.9-1.4-1.3-1.51.51.6-1.6-1.5
Bone: trabecular thickness0.40.51.0-0.90.8-0.80.90.6-0.60.71.00.6-0.5-0.50.50.3
Bone: trabecular tissue density2.53.63.9-1.91.8-1.91.91.8-1.82.01.91.9-2.0-1.91.91.8
Water consumed over 24 hours0.40.41.30.2-0.10.5-0.2-0.40.4-0.6-0.3-0.80.91.0-0.8-1.1
Number of responses in last shaping day1.41.42.90.8-1.01.1-1.0-0.50.5-1.3-0.8-1.51.21.6-1.6-1.7