Dpf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	PL	gene expression	Dpf1	0.8	0	8.3e-16	0.11	0.13	0.13	0.13	8.8e-12	7.0e-14	6.3e-14	1.3e-13
2	BLA	gene expression	Dpf1	0.55	0.15	1.0e-09	0.17	0.18	0.16	0.18	3.3e-09	1.2e-09	1.2e-08	4.8e-10
3	IC	gene expression	Dpf1	0.47	0.16	1.7e-14	0.28	0.26	0.27	0.28	3.4e-12	3.0e-11	7.5e-12	5.5e-12
4	IC	intron excision ratio	chr1_93740103_93740197	0.08	0.07	2.0e-03	0.03	0.05	0.03	0.03	1.4e-02	2.8e-03	2.5e-02	1.9e-02
5	BLA	intron excision ratio	chr1_93737259_93738812	0.05	0.04	1.9e-03	0.02	0.04	0.02	0.02	2.7e-02	5.0e-03	2.1e-02	4.0e-02
6	NAcc	gene expression	Dpf1	0.15	0.08	0.0e+00	0.16	0.15	0.15	0.16	3.4e-23	2.8e-22	1.9e-22	6.0e-23
7	OFC	gene expression	Dpf1	0.52	0.19	3.3e-06	0.22	-0.01	0.17	0.01	7.7e-06	9.7e-01	7.3e-05	1.8e-01
8	RMTg	intron excision ratio	chr1_93737259_93737476	0.12	0.1	9.4e-03	0.09	0.02	0.06	0.06	3.0e-03	9.6e-02	9.3e-03	9.4e-03
9	NAcc	isoform ratio	NM_001105729.3	0.03	0.03	6.4e-03	0.02	0	0.01	0	1.6e-03	9.7e-02	3.4e-02	2.0e-01
10	PL	intron excision ratio	chr1_93737259_93738812	0.04	0.03	9.5e-06	0.04	0.01	0.04	0.01	1.2e-05	2.3e-02	2.6e-05	3.5e-02
11	NAcc	intron excision ratio	chr1_93737259_93738812	0.06	0.04	4.9e-07	0.05	0.04	0.03	0.04	7.7e-08	3.8e-06	6.8e-06	3.6e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.0	0.1	0.7	0.1	-0.2	-0.0	0.0	0.0	-0.2	-0.3	0.8	0.1	0.2	0.2
Area under the delay curve	0.8	1.0	2.1	1.3	1.1	1.3	0.9	-1.0	1.4	1.2	1.1	0.0	-0.0	0.0
BMI with tail	0.1	0.4	0.7	-0.5	-0.7	-0.8	-0.6	0.6	-0.8	-0.9	-0.3	-0.3	0.6	0.5
BMI without tail	0.5	1.7	2.4	1.4	1.2	1.1	1.4	-1.3	1.1	1.2	1.4	1.5	-1.3	-1.3
Body weight	2.4	10.5	12.3	3.3	3.2	3.0	3.4	-3.4	3.0	2.9	3.4	3.5	-3.2	-3.2
Weight adjusted by age	0.1	0.1	0.3	-0.6	-0.3	-0.6	-0.2	0.2	-0.5	-0.1	-0.5	0.1	-0.1	0.0
Bone surface	0.5	0.8	2.7	0.9	0.7	0.8	0.9	-0.9	0.6	0.6	1.7	1.0	-0.7	-0.7
Bone volume	0.5	0.9	2.3	1.0	0.8	0.9	0.9	-0.9	0.7	0.7	1.5	1.1	-0.8	-0.8
Breakpoint value in progressive ratio session	2.4	2.9	4.2	1.8	1.7	2.1	1.8	-1.8	2.0	1.4	1.7	1.2	-1.4	-1.4
Number of licking bursts	2.2	3.6	5.7	-2.2	-1.8	-2.0	-2.0	2.0	-1.9	-1.8	-2.4	-1.7	1.5	1.6
Context. condit. distance diff. score	0.1	0.1	0.2	-0.1	-0.4	-0.2	-0.2	0.2	-0.1	-0.4	-0.1	-0.3	0.4	0.3
Locomotion velocity, session 1	1.6	1.7	3.6	-1.3	-1.2	-1.0	-1.3	1.3	-0.9	-1.0	-0.8	-1.9	1.6	1.7
Locomotion distance, session 1	0.7	0.9	1.1	0.9	1.0	0.9	1.0	-0.9	1.0	0.9	0.9	0.9	-1.0	-1.0
Locomotion velocity, session 2	0.6	0.7	1.3	-0.8	-1.0	-0.7	-0.7	0.7	-0.9	-1.1	-0.7	-0.7	0.7	0.8
Locomotion distance, session 2	1.1	1.6	2.8	-1.4	-1.3	-1.5	-1.3	1.3	-1.7	-1.4	-1.2	-0.7	0.8	0.8
Locomotion velocity, session 3	0.4	0.4	0.9	-0.9	-0.7	-0.8	-0.6	0.6	-1.0	-0.6	-0.7	-0.4	0.3	0.4
Locomotion distance, session 3	4.9	5.4	7.8	2.3	2.3	1.9	2.4	-2.4	1.8	2.3	1.8	2.8	-2.6	-2.6
Stereotopy head waving bouts, day 3	1.1	1.3	2.5	-1.5	-1.3	-1.2	-1.0	1.1	-1.6	-1.4	-0.8	-0.8	0.5	0.6
Stereotopy head waving duration, day 3	2.8	3.3	4.4	-2.1	-2.1	-1.7	-1.8	1.8	-2.1	-2.1	-1.3	-1.7	1.6	1.7
Locomotion velocity, session 7	0.1	0.1	0.4	0.4	0.0	0.2	0.2	-0.2	0.2	0.0	0.6	0.2	0.0	0.0
Locomotion distance, session 7	0.1	0.1	0.3	0.5	0.4	0.2	0.3	-0.3	0.2	0.4	0.5	0.5	-0.3	-0.3
Stereotopy head waving bouts, day 7	0.8	0.9	2.2	-1.1	-0.8	-1.0	-1.0	0.9	-1.3	-0.7	-1.5	-0.4	0.5	0.5
Stereotopy head waving duration, day 7	1.4	1.7	3.0	-1.4	-1.3	-1.3	-1.4	1.3	-1.6	-1.3	-1.7	-1.0	1.0	1.0
Locomotion velocity, session 8	4.2	5.0	6.1	-2.4	-2.4	-2.4	-2.3	2.3	-2.4	-2.5	-2.2	-2.0	2.0	1.9
Locomotion distance, session 8	0.6	0.8	1.1	-0.9	-1.0	-1.0	-0.9	0.9	-0.9	-1.0	-1.0	-0.8	0.8	0.8
Degree of sensitization distance	2.2	2.2	3.8	-1.3	-1.6	-1.1	-1.5	1.5	-1.1	-1.5	-0.7	-1.9	2.0	1.9
Degree of sensitization stereotypy	0.3	0.3	1.6	-0.6	-0.2	-0.5	-0.5	0.4	-0.7	-0.1	-1.3	0.1	-0.0	0.0
Conditioned locomotion	0.3	0.3	0.9	-0.5	-0.1	-0.2	0.1	-0.1	-0.4	-0.4	-0.5	0.7	-0.9	-1.0
Cocaine response after cond. corrected	0.2	0.3	0.8	0.6	0.5	0.3	0.4	-0.5	0.3	0.4	-0.2	0.9	-0.7	-0.7
Cocaine response after cond. not corrected	0.3	0.3	1.2	0.4	0.4	0.1	0.4	-0.4	-0.0	0.1	-0.1	1.1	-0.9	-1.0
Cocaine response before conditioning	0.8	0.9	2.3	0.5	0.6	0.3	0.9	-0.8	0.2	0.4	1.2	1.3	-1.5	-1.5
Saline control response	0.0	0.1	0.2	0.3	0.2	0.1	0.2	-0.2	0.2	-0.1	-0.2	0.4	-0.3	-0.3
Bone: connectivity density	0.2	0.3	0.6	-0.3	-0.7	-0.3	-0.4	0.5	-0.5	-0.7	0.6	-0.6	0.8	0.8
Bone: cortical apparent density	2.4	3.3	4.1	-1.8	-1.8	-2.0	-1.9	2.0	-1.8	-1.5	-1.5	-1.9	1.8	1.8
Bone: cortical area	2.1	3.2	4.4	1.5	1.7	1.7	1.9	-1.9	1.7	1.5	1.7	2.0	-2.1	-2.0
Bone: cortical porosity	1.2	1.3	2.2	-1.3	-1.3	-1.4	-1.1	1.2	-1.5	-1.5	-1.1	-0.5	0.5	0.5
Bone: cortical porosity	1.6	1.7	2.9	-1.6	-1.5	-1.5	-1.3	1.3	-1.7	-1.6	-1.4	-0.6	0.6	0.6
Bone: cortical thickness	1.0	1.7	2.7	1.0	1.3	1.2	1.4	-1.4	1.1	1.1	1.1	1.5	-1.7	-1.6
Bone: cortical thickness	0.4	0.5	1.0	-1.0	-0.7	-0.8	-0.5	0.5	-0.9	-0.9	-0.8	-0.2	-0.0	-0.0
Bone: cortical tissue density	2.8	3.7	4.6	-1.9	-1.9	-2.2	-2.0	2.1	-2.0	-1.6	-1.6	-2.0	1.9	1.9
Condit. Reinf. active minus inactive responses	0.2	0.3	0.5	-0.7	-0.6	-0.3	-0.5	0.6	-0.4	-0.5	-0.4	-0.7	0.5	0.4
Condit. Reinf. active-inactive response ratio	0.1	0.2	0.2	-0.5	-0.5	-0.2	-0.4	0.4	-0.4	-0.5	-0.3	-0.5	0.3	0.3
Condit. Reinf. active responses	1.5	1.9	2.4	-1.6	-1.4	-1.3	-1.5	1.5	-1.4	-1.5	-1.4	-1.2	1.1	1.1
Condit. Reinf. inactive responses	1.2	1.5	2.1	-1.3	-1.1	-1.3	-1.4	1.3	-1.3	-1.2	-1.4	-0.9	0.9	1.0
Incentive salience index mean	0.1	0.1	0.2	-0.4	-0.4	-0.3	-0.3	0.4	-0.3	-0.4	-0.2	-0.2	0.1	0.1
Condit. Reinf. lever presses	0.0	0.1	0.2	0.2	0.1	0.1	0.2	-0.1	0.1	0.1	0.3	0.4	-0.4	-0.3
Condit. Reinf. active minus inactive responses	3.1	4.0	5.5	1.8	2.0	1.8	2.1	-2.1	1.7	1.9	1.6	2.2	-2.3	-2.3
Condit. Reinf. active-inactive response ratio	1.2	1.4	3.4	0.7	1.1	0.7	1.1	-1.1	0.6	0.8	-0.1	1.7	-1.8	-1.9
Condit. Reinf. active responses	4.4	6.1	6.9	2.3	2.4	2.3	2.6	-2.6	2.2	2.4	2.5	2.4	-2.6	-2.6
Condit. Reinf. inactive responses	2.3	3.0	5.9	1.8	1.7	1.8	1.8	-1.8	1.8	1.9	2.4	1.1	-1.3	-1.3
Condit. Reinf. lever presses	8.7	12.0	13.6	3.6	3.7	3.7	3.6	-3.6	3.6	3.6	3.5	2.9	-3.0	-3.1
Condit. Reinf. lever reinforcers received	5.1	7.1	8.5	2.5	2.7	2.5	2.8	-2.8	2.3	2.6	2.6	2.7	-2.9	-2.9
Conditioned reinforcement - actives	0.3	0.5	1.1	-0.8	-0.7	-0.6	-0.7	0.7	-1.1	-0.7	-1.1	-0.2	0.4	0.4
Conditioned reinforcement - inactives	0.4	0.6	1.1	0.6	0.6	0.8	0.8	-0.8	0.4	0.7	0.5	1.0	-0.9	-0.9
Conditioned locomotion	3.0	4.0	7.1	-2.1	-2.3	-2.1	-2.0	2.0	-2.7	-2.3	-1.6	-1.4	1.6	1.5
Patch foraging indifference point 0 sec	0.1	0.2	0.4	0.3	0.4	0.2	0.5	-0.5	0.3	0.6	0.3	0.5	-0.7	-0.7
Patch foraging indifference point AUC	0.5	0.7	1.2	-0.9	-0.8	-0.9	-0.9	0.9	-1.1	-0.5	-0.9	-0.4	0.8	0.7
Delay disc. indifference point, 0s delay	0.9	1.0	1.8	1.3	1.1	1.2	1.0	-1.0	1.4	1.2	0.9	0.5	-0.3	-0.4
Delay disc. indifference point, 16s delay	2.7	3.0	4.6	2.1	1.9	2.1	1.7	-1.7	2.2	2.0	1.6	1.2	-1.1	-0.9
Delay disc. indifference point, 2s delay	0.8	0.9	2.0	1.1	0.9	1.3	0.8	-0.9	1.4	1.2	1.1	-0.3	0.4	0.3
Delay disc. indifference point, 24s delay	2.1	2.4	3.5	1.9	1.7	1.6	1.6	-1.6	1.7	1.8	1.6	1.3	-1.1	-1.1
Delay disc. indifference point, 4s delay	0.3	0.3	0.7	0.7	0.6	0.7	0.5	-0.5	0.8	0.6	0.2	-0.0	-0.1	-0.1
Delay disc. indifference point, 8s delay	0.3	0.4	1.3	0.2	-0.3	0.1	-0.2	0.3	0.2	-0.2	0.4	-1.1	1.0	1.1
Indifference point function ln k	0.3	0.6	0.8	0.8	0.8	0.8	0.8	-0.8	0.9	0.9	0.8	0.5	-0.7	-0.7
Indifference point function log k	0.3	0.6	0.8	0.8	0.8	0.8	0.8	-0.8	0.9	0.9	0.8	0.5	-0.7	-0.7
Patch foraging total patch changes 0 sec	0.2	0.3	0.5	0.4	0.6	0.3	0.6	-0.6	0.4	0.7	0.4	0.7	-0.7	-0.7
Patch foraging total patch changes 12 sec	0.1	0.2	0.4	0.3	0.3	0.2	0.4	-0.4	-0.0	0.5	0.3	0.6	-0.5	-0.6
Patch foraging total patch changes 18 sec	0.3	0.5	0.9	-0.9	-0.8	-0.9	-0.7	0.7	-1.0	-0.4	-0.6	-0.3	0.5	0.5
Patch foraging total patch changes 24 sec	0.4	0.8	1.7	0.8	1.0	0.8	0.9	-0.9	0.7	1.3	0.6	0.9	-0.8	-0.8
Patch foraging total patch changes 6 sec	0.0	0.1	0.2	-0.2	-0.1	-0.2	0.0	-0.1	-0.3	-0.0	-0.3	0.4	-0.2	-0.4
Patch foraging time to switch 0 sec	0.5	1.0	1.8	-0.6	-1.2	-0.7	-0.9	0.9	-0.8	-1.3	-0.4	-1.2	1.4	1.2
Patch foraging water rate 0 sec	0.6	1.2	2.0	-1.4	-1.1	-1.3	-1.1	1.1	-1.2	-0.9	-1.3	-0.9	0.7	0.7
Patch foraging water rate 12 sec	0.5	1.0	1.5	0.7	1.2	1.1	1.0	-1.1	1.2	1.2	0.1	0.8	-1.2	-1.1
Patch foraging water rate 18 sec	0.3	0.4	1.4	-0.5	-0.3	-0.1	-0.5	0.5	-0.0	-0.3	-0.6	-1.2	0.8	1.0
Patch foraging water rate 24 sec	0.2	0.2	0.6	0.1	0.6	0.5	0.4	-0.4	0.5	0.4	-0.2	0.4	-0.7	-0.7
Patch foraging water rate 6 sec	0.2	0.3	0.7	0.4	0.6	0.7	0.5	-0.5	0.7	0.8	0.5	0.0	-0.3	-0.2
Seeking ratio, delayed vs. immediate footshock	1.4	1.7	2.1	1.2	1.4	1.4	1.4	-1.4	1.4	1.5	1.1	1.3	-1.2	-1.2
Distance traveled before self-admin	1.7	2.2	3.1	1.1	1.6	1.5	1.6	-1.6	1.5	1.3	1.1	1.4	-1.8	-1.8
Distance traveled after self-admin	2.5	3.0	3.4	1.7	1.8	1.7	1.8	-1.8	1.6	1.7	1.7	1.8	-1.8	-1.8
Extensor digitorum longus weight	0.2	0.9	1.0	-0.9	-1.0	-0.9	-1.0	1.0	-0.9	-0.9	-0.9	-0.9	0.9	1.0
Bone: elastic displacement	0.0	0.0	0.0	-0.1	-0.0	0.0	-0.0	0.0	-0.2	0.1	-0.0	-0.1	0.1	0.1
Bone: elastic work	2.3	3.0	4.0	1.5	1.7	1.6	1.8	-1.8	1.6	1.7	1.6	1.8	-1.9	-2.0
Bone: endosteal estimation	1.4	3.0	4.0	2.0	1.8	1.7	1.8	-1.7	1.7	1.6	2.0	1.8	-1.4	-1.4
Bone: endosteal perimeter	1.3	2.8	3.5	1.9	1.7	1.8	1.7	-1.7	1.9	1.6	1.9	1.4	-1.3	-1.3
Epididymis fat weight	0.0	0.1	0.5	-0.1	-0.2	-0.7	-0.3	0.3	-0.5	-0.2	-0.2	0.3	-0.1	-0.1
Delta time in closed arm before/after self-admin	0.3	0.3	0.9	0.9	0.5	0.7	0.3	-0.4	0.6	0.6	0.6	0.3	0.3	0.3
Delta time in open arm before/after self-admin	0.2	0.2	0.7	-0.7	-0.2	-0.4	-0.2	0.2	-0.4	-0.4	-0.9	0.0	-0.5	-0.5
Diff in mean of infusions in LGA sessions	0.0	0.0	0.1	0.2	0.2	0.0	0.2	-0.2	0.3	-0.1	-0.0	-0.1	-0.3	-0.3
Delay discount exponential model param	0.9	1.0	2.1	-1.3	-1.1	-1.2	-0.9	1.0	-1.5	-1.2	-1.0	-0.1	0.1	0.0
Extinction: sum of active levers before priming	2.4	2.7	5.7	1.7	1.5	1.2	1.7	-1.6	1.3	1.5	2.4	1.6	-1.7	-1.7
Active lever presses in extinction session 6	0.9	0.9	2.9	1.3	0.8	1.1	0.9	-0.9	0.9	0.8	1.7	0.6	-0.4	-0.4
Bone: final force	1.6	2.5	2.9	1.5	1.6	1.4	1.6	-1.6	1.4	1.5	1.7	1.7	-1.7	-1.7
Bone: final moment	2.4	3.8	4.6	1.9	2.0	1.7	2.0	-2.0	1.7	1.8	2.0	2.1	-2.2	-2.1
Food consumed during 24 hour testing period	0.3	0.4	0.8	0.6	0.7	0.6	0.8	-0.8	0.6	0.8	0.9	0.3	-0.6	-0.5
Glucose	0.1	0.2	0.5	-0.1	-0.2	-0.6	-0.6	0.5	-0.4	0.0	-0.7	-0.2	0.6	0.7
Heart weight	0.6	0.9	2.3	0.5	0.7	0.7	0.9	-1.0	0.5	0.3	0.2	1.4	-1.5	-1.5
Delay discount hyperbolic model param	0.7	0.7	1.7	-1.1	-0.9	-1.1	-0.8	0.8	-1.3	-1.0	-0.9	0.2	-0.1	-0.2
Intermittent access intake day 1-15 change	0.4	0.8	1.9	1.0	0.9	0.8	1.0	-1.0	0.7	1.4	1.0	0.9	-0.5	-0.5
Intermittent access intake escalation	0.2	0.4	1.2	0.7	0.7	0.5	0.7	-0.7	0.4	1.1	0.7	0.7	-0.4	-0.4
Intermittent access intake escalation 2	1.9	2.2	2.9	1.6	1.6	1.3	1.5	-1.5	1.4	1.7	1.1	1.7	-1.5	-1.4
Intermitt. access day 1 inactive lever presses	1.6	6.1	8.9	2.9	2.6	2.3	2.5	-2.4	2.5	2.7	3.0	2.2	-2.1	-2.0
Intermitt. access day 15 inactive lever presses	0.7	1.4	2.1	1.4	1.4	1.3	1.2	-1.2	1.5	1.2	1.3	0.8	-0.9	-0.9
Intermitt. access escalation Index	0.2	0.2	0.5	0.2	0.5	0.5	0.4	-0.5	0.5	0.2	-0.1	0.6	-0.7	-0.7
Intermittent access day 1 total infusions	0.6	1.0	2.4	-1.6	-1.1	-0.8	-0.8	0.8	-1.0	-1.3	-1.2	-0.8	0.3	0.3
Intermittent access day 15 total infusions	0.0	0.1	0.2	-0.3	0.0	0.2	0.2	-0.2	-0.2	0.1	-0.1	0.1	-0.4	-0.4
Intermittent access terminal intake (last 3 days)	0.3	0.4	1.0	0.1	0.5	0.6	0.5	-0.6	0.3	0.4	-0.1	0.7	-1.0	-1.0
Intermittent access total infusions	0.1	0.1	0.5	-0.7	-0.3	-0.0	-0.2	0.2	-0.5	-0.4	-0.5	-0.2	-0.2	-0.2
Intermittent access day 1 locomotion	0.2	0.2	0.7	-0.8	-0.5	-0.5	-0.3	0.3	-0.7	-0.7	-0.4	-0.1	-0.2	-0.2
Intermittent access day 15 total locomotion	0.1	0.2	0.7	-0.5	-0.6	-0.5	-0.3	0.3	-0.8	-0.5	-0.1	-0.1	0.2	0.2
Intermittent access total locomotion	0.8	0.9	2.1	-1.1	-1.1	-0.9	-0.9	0.9	-1.4	-1.1	-0.9	-0.5	0.5	0.5
Intermittent access standard deviation	2.1	4.4	6.0	2.0	2.2	2.2	2.2	-2.2	2.1	2.5	2.3	1.6	-1.9	-1.8
Left kidney weight	2.1	9.7	19.4	2.9	2.8	2.2	3.1	-3.0	2.0	2.2	2.3	4.4	-4.0	-4.1
Right kidney weight	2.5	11.4	17.2	3.4	3.2	2.8	3.4	-3.4	2.7	2.6	3.1	4.1	-4.0	-4.0
Cocaine induced anxiety	0.1	0.2	0.7	0.1	-0.1	0.1	-0.2	0.2	0.3	-0.3	0.1	-0.8	0.6	0.6
Post-drug Anxiety	0.2	0.2	0.7	0.5	0.5	0.7	0.4	-0.4	0.8	0.4	0.3	-0.2	0.0	0.0
Baseline Anxiety	0.6	0.7	1.9	0.4	0.7	0.4	0.7	-0.8	0.4	0.7	0.2	1.4	-1.3	-1.3
Tail length	5.7	22.1	24.2	4.9	4.9	4.7	4.8	-4.9	4.6	4.8	4.3	4.8	-4.5	-4.4
Length with tail	7.2	31.1	33.7	5.6	5.7	5.7	5.8	-5.8	5.6	5.5	5.2	5.6	-5.5	-5.4
Length without tail	2.1	6.8	7.7	2.7	2.7	2.8	2.7	-2.7	2.8	2.6	2.5	2.4	-2.3	-2.3
Times rat made contact with spout	1.1	1.3	2.0	-1.4	-1.2	-1.4	-1.1	1.1	-1.4	-1.2	-1.2	-0.6	0.6	0.6
Lifetime Intake	0.3	0.4	1.1	-1.0	-0.6	-0.4	-0.5	0.5	-0.8	-0.6	-0.8	-0.4	0.1	0.1
Liver weight, left	0.1	0.2	1.0	0.0	0.1	-0.5	-0.2	0.1	-0.2	-0.3	-1.0	0.8	-0.5	-0.5
Liver weight, right	0.0	0.1	0.4	0.1	0.2	-0.1	-0.0	-0.0	0.0	0.1	-0.6	0.3	-0.2	-0.2
Locomotor activity	0.7	1.2	2.3	-1.0	-1.2	-1.3	-1.1	1.1	-1.2	-1.5	-0.9	-0.5	0.8	0.9
Locomotor testing distance	1.3	2.3	2.8	-1.6	-1.6	-1.7	-1.6	1.6	-1.7	-1.7	-1.1	-1.2	1.3	1.3
Locomotor testing rearing	1.7	3.5	4.9	-2.2	-2.0	-2.0	-1.9	1.8	-2.0	-2.2	-2.2	-1.4	1.4	1.2
Locomotion in novel chamber	0.3	0.4	0.9	-0.1	-0.6	-0.4	-0.5	0.5	-0.4	-0.6	0.2	-0.8	1.0	1.0
Locomotion in novel chamber post-restriction	0.3	0.4	1.3	0.5	0.6	0.8	0.7	-0.7	0.8	0.8	1.1	-0.2	-0.0	-0.0
Fecal boli incidents, locomotor time 1	1.8	2.6	4.8	-1.2	-1.6	-1.3	-1.7	1.7	-1.4	-1.4	-0.9	-1.9	2.2	2.1
Change in fecal boli incidents, locomotor task	0.0	0.0	0.1	-0.3	-0.2	-0.2	-0.0	0.1	-0.1	-0.2	-0.0	-0.0	-0.2	-0.1
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.0	0.2	0.0	0.1	-0.0	0.0	-0.0	0.0	-0.1	0.2	0.1	0.1
Bouts of movement, locomotor time 1	1.8	2.1	4.9	1.5	1.5	2.2	1.4	-1.5	1.9	1.7	1.1	0.6	-0.5	-0.4
Total resting periods, locomotor time 1	1.7	1.8	4.6	1.4	1.4	2.1	1.3	-1.4	1.8	1.7	1.2	0.3	-0.4	-0.3
Rest time, locomotor task time 1	0.1	0.1	0.3	-0.5	-0.2	-0.2	-0.3	0.3	-0.3	-0.0	-0.5	-0.3	0.3	0.4
Distance moved, locomotor task time 1	0.1	0.2	0.5	-0.2	-0.2	-0.4	-0.1	0.1	-0.4	-0.4	-0.4	0.7	-0.4	-0.5
Vertical activity count, locomotor time 1	0.4	0.9	2.2	0.9	0.8	0.6	1.0	-1.0	0.6	0.6	0.9	1.5	-1.2	-1.1
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.9	-0.2	0.1	-0.2	-0.1	0.1	-0.1	0.0	-1.0	0.4	-0.3	-0.3
Bouts of movement, locomotor time 2	0.1	0.2	0.6	0.4	0.2	0.8	0.2	-0.2	0.6	0.3	0.2	-0.6	0.5	0.7
Total resting periods, locomotor time 2	0.1	0.1	0.5	0.2	-0.0	0.5	-0.0	-0.0	0.3	0.1	0.0	-0.6	0.5	0.7
Rest time, locomotor task time 2	0.1	0.2	0.4	-0.2	0.4	0.2	0.3	-0.3	0.0	0.4	-0.3	0.6	-0.6	-0.6
Distance moved, locomotor task time 2	0.2	0.3	0.7	-0.4	-0.5	-0.7	-0.5	0.5	-0.5	-0.7	-0.9	0.1	0.2	0.1
Vertical activity count, locomotor time 2	0.2	0.3	0.7	0.8	0.5	0.6	0.6	-0.6	0.7	0.5	0.6	0.6	-0.2	-0.3
Light reinforcement 1	0.1	0.3	0.6	-0.6	-0.5	-0.6	-0.6	0.5	-0.6	-0.5	-0.7	-0.6	0.6	0.5
Light reinforcement 2	4.8	7.3	11.0	-2.5	-2.8	-2.3	-2.7	2.7	-2.3	-2.6	-1.9	-3.3	3.2	3.2
Bone: marrow area	1.4	3.1	4.2	2.0	1.8	1.7	1.8	-1.8	1.7	1.7	2.0	1.8	-1.5	-1.4
Bone: maximum diameter	1.4	2.6	3.5	1.5	1.5	1.6	1.7	-1.7	1.5	1.2	1.7	1.9	-1.8	-1.7
Bone: maximum force	3.1	5.5	6.0	2.3	2.5	2.1	2.4	-2.4	2.2	2.3	2.3	2.4	-2.4	-2.4
Bone: maximum moment	4.0	7.0	8.0	2.6	2.8	2.4	2.7	-2.7	2.4	2.6	2.5	2.8	-2.8	-2.7
Mean time between licks in bursts	0.0	0.1	0.4	0.1	0.3	0.2	0.4	-0.4	0.2	0.2	0.2	0.4	-0.6	-0.6
Mean num. licks in bursts	0.6	1.0	1.8	1.1	0.8	0.9	1.1	-1.0	0.7	0.7	1.3	1.1	-1.0	-1.0
Cd content in liver	0.5	0.6	0.7	-0.8	-0.7	-0.7	-0.8	0.8	-0.7	-0.8	-0.7	-0.8	0.8	0.8
Co content in liver	1.0	1.2	1.7	-1.1	-1.3	-1.1	-1.0	1.1	-1.1	-1.3	-0.7	-1.1	1.1	1.1
Cu content in liver	1.1	1.3	1.7	0.9	1.2	1.2	1.2	-1.2	1.1	1.1	1.0	1.1	-1.3	-1.3
Fe content in liver	0.5	0.6	1.3	-0.5	-0.7	-0.6	-0.8	0.8	-0.6	-0.5	-0.4	-1.0	1.2	1.2
K content in liver	0.4	0.4	0.9	0.5	0.7	0.4	0.6	-0.7	0.4	0.6	0.2	0.9	-0.9	-0.9
Mg content in liver	0.1	0.1	0.4	-0.5	-0.2	-0.4	-0.1	0.1	-0.4	-0.3	-0.6	0.3	-0.5	-0.5
Mn content in liver	0.5	0.5	1.3	-0.6	-0.2	-0.8	-0.1	0.1	-0.8	-0.3	-0.6	1.1	-1.0	-1.0
Na content in liver	2.2	2.3	3.9	1.5	1.6	1.2	1.5	-1.5	1.1	1.4	0.9	2.0	-1.8	-1.8
Rb content in liver	0.0	0.0	0.1	-0.1	-0.1	0.0	-0.0	0.0	-0.1	-0.3	-0.3	-0.1	-0.2	-0.2
Se content in liver	4.6	5.4	7.3	-2.5	-2.4	-2.7	-2.4	2.4	-2.7	-2.3	-2.4	-1.7	1.8	1.8
Sr content in liver	0.5	0.4	0.9	-0.6	-0.7	-0.6	-0.6	0.6	-0.6	-1.0	-0.5	-0.6	0.6	0.6
Zn content in liver	3.4	3.7	5.7	-2.2	-2.1	-2.1	-1.9	1.9	-2.2	-2.4	-1.8	-1.5	1.4	1.4
Bone: minimum diameter	5.3	9.7	11.3	3.1	3.2	3.0	3.3	-3.3	3.0	2.8	2.7	3.4	-3.3	-3.3
Time in familiar zone, hab. session 1	0.3	0.3	0.5	0.7	0.6	0.7	0.5	-0.6	0.6	0.4	0.6	0.5	-0.4	-0.4
Time in novel zone, hab. session 1	0.3	0.3	1.1	-0.7	-0.5	-0.6	-0.6	0.5	-0.6	-0.5	-1.0	-0.3	0.2	0.2
Total zone transitions, hab. session 1	0.3	0.4	0.8	0.6	0.7	0.3	0.5	-0.5	0.3	0.8	0.3	0.9	-0.7	-0.8
Total locomotion distance, hab. session 1	3.2	4.5	6.2	2.1	2.4	2.1	2.1	-2.1	2.2	2.5	1.9	2.0	-1.9	-2.0
Locomotion velocity, hab. session 1	1.5	2.1	3.6	1.4	1.6	1.4	1.4	-1.4	1.5	1.9	1.5	1.2	-1.3	-1.3
Time in familiar zone, hab. session 2	1.3	1.3	2.5	1.4	1.1	1.6	1.2	-1.2	1.4	1.1	1.6	0.5	-0.5	-0.5
Time in novel zone, hab. session 2	0.9	0.9	1.5	-1.1	-0.9	-1.2	-1.0	1.0	-1.0	-0.8	-1.2	-0.7	0.6	0.6
Total zone transitions, hab. session 2	1.0	1.2	3.2	-1.3	-0.9	-1.4	-1.0	1.0	-1.5	-1.2	-1.8	-0.2	0.1	0.1
Total locomotion distance, hab. session 2	0.2	0.2	0.7	0.1	0.4	0.3	0.4	-0.4	0.2	0.3	-0.1	0.6	-0.8	-0.8
Locomotion velocity, hab. session 2	0.1	0.2	0.6	-0.2	0.2	-0.0	0.2	-0.2	-0.1	0.1	-0.2	0.5	-0.8	-0.8
Novel to familiar place preference ratio	0.8	0.9	1.3	0.8	1.1	0.8	0.9	-0.9	0.7	1.1	0.2	1.1	-1.1	-1.1
Novelty place preference	0.7	0.7	1.3	0.7	1.1	0.7	0.7	-0.8	0.7	1.1	-0.0	1.0	-1.0	-1.0
Time in novel zone, NPP test	0.4	0.4	0.7	0.5	0.8	0.5	0.5	-0.6	0.4	0.9	-0.2	0.8	-0.8	-0.8
Total zone transitions, NPP test	0.1	0.2	0.4	-0.3	-0.4	-0.5	-0.5	0.5	-0.5	-0.3	-0.2	-0.5	0.6	0.6
Total locomotion distance, NPP test	2.2	3.1	4.2	1.7	1.8	1.8	1.8	-1.8	1.8	2.0	2.1	1.3	-1.4	-1.4
Locomotion velocity, NPP test	2.6	3.7	4.7	1.9	2.0	2.0	2.0	-2.0	1.9	2.2	2.2	1.6	-1.7	-1.6
Intraocular pressure	0.1	0.1	0.2	0.3	0.2	0.4	-0.0	-0.0	0.4	0.3	0.3	-0.2	0.4	0.4
Delta distance traveled before/after self-admin	0.2	0.2	0.7	0.8	0.2	0.5	0.3	-0.2	0.3	0.4	0.8	0.0	0.3	0.3
Delta ambulatory time before/after self-admin	0.1	0.2	0.5	0.6	0.3	0.4	0.3	-0.3	0.3	0.3	0.7	0.5	-0.1	-0.1
Parametrial fat weight	0.3	0.8	1.3	-1.1	-1.0	-1.0	-0.8	0.8	-1.1	-1.1	-0.9	-0.5	0.5	0.4
Pavlov. Cond. lever latency	0.1	0.1	0.5	0.1	-0.1	0.3	-0.1	0.1	0.3	-0.0	0.1	-0.7	0.7	0.6
Pavlov. Cond. magazine entry latency	0.2	0.3	0.7	-0.6	-0.4	-0.4	-0.6	0.6	-0.4	-0.3	-0.8	-0.6	0.5	0.5
Pavlov. Cond. change in total contacts	0.0	0.0	0.1	0.0	-0.0	-0.1	-0.2	0.1	-0.1	-0.1	-0.4	0.1	-0.0	0.0
Pavlov. Cond. index score	0.1	0.2	0.4	-0.5	-0.3	-0.6	-0.4	0.4	-0.6	-0.4	-0.6	0.1	-0.1	-0.1
Pavlov. Cond. latency score	0.1	0.1	0.2	-0.3	-0.2	-0.4	-0.2	0.2	-0.4	-0.3	-0.3	0.3	-0.3	-0.2
Pavlov. Cond. lever contacts	0.4	0.4	1.0	0.5	0.6	0.2	0.6	-0.6	0.3	0.6	0.4	1.0	-1.0	-0.9
Pavlov. Cond. magazine entry number	0.1	0.1	0.5	0.4	0.2	0.3	0.4	-0.4	0.3	0.1	0.7	0.3	-0.2	-0.3
Pavlov. Cond. intertrial magazine entries	0.4	0.5	1.0	-0.7	-0.8	-0.9	-0.7	0.7	-0.8	-1.0	-1.0	-0.3	0.3	0.3
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	0.7	-0.5	-0.3	-0.6	-0.4	0.4	-0.6	-0.4	-0.8	0.2	-0.2	-0.1
Pavlov. Cond. response bias	0.0	0.0	0.2	-0.2	-0.0	-0.2	-0.2	0.2	-0.2	0.1	-0.5	0.1	-0.2	-0.1
Pavlov. Cond. lever latency	4.7	6.4	7.5	-2.7	-2.7	-2.7	-2.7	2.6	-2.6	-2.6	-2.7	-2.1	2.2	2.2
Pavlov. Cond. magazine entry latency	3.2	3.9	5.3	2.2	2.1	2.3	2.1	-2.0	2.0	2.0	2.2	1.5	-1.6	-1.6
Pavlov. Cond. change in total contacts	6.9	11.0	13.4	3.5	3.5	3.7	3.5	-3.5	3.5	3.4	3.4	2.7	-2.9	-2.9
Pavlov. Cond. index score	5.1	6.9	8.9	2.9	2.8	3.0	2.7	-2.7	2.7	2.7	2.9	2.0	-2.1	-2.1
Pavlov. Cond. latency score	4.6	6.1	7.8	2.7	2.6	2.8	2.6	-2.5	2.6	2.6	2.7	1.8	-1.9	-2.0
Pavlov. Cond. lever contacts	5.3	7.3	8.8	2.9	2.9	3.0	2.8	-2.8	2.8	2.8	2.8	2.2	-2.3	-2.4
Pavlov. Cond. magazine entry number	3.1	3.8	5.9	-2.3	-2.1	-2.4	-2.0	1.9	-2.2	-2.2	-2.2	-1.1	1.2	1.3
Pavlov. Cond. intertrial magazine entries	1.5	2.3	4.1	-1.9	-1.6	-2.0	-1.6	1.6	-1.7	-1.5	-1.4	-1.1	1.0	1.1
Pavlov. Cond. lever-magazine prob. diff.	5.1	6.8	8.6	2.9	2.8	2.9	2.7	-2.7	2.7	2.7	2.8	2.1	-2.1	-2.2
Pavlov. Cond. response bias	6.1	8.4	10.0	3.1	3.1	3.2	3.0	-3.0	3.0	3.0	2.9	2.4	-2.5	-2.5
Time in closed arm before self-admin	0.2	0.3	1.2	-0.9	-0.4	-0.4	-0.4	0.3	-0.1	-0.8	-1.1	-0.5	-0.0	-0.0
Time in closed arm after self-admin	0.6	0.7	1.9	0.9	0.7	1.2	0.8	-0.8	1.4	0.6	1.0	-0.1	0.1	0.1
Time in open arm before self-admin	1.4	1.5	4.1	1.5	1.1	1.0	1.2	-1.1	0.9	1.2	2.0	1.2	-0.9	-0.9
Time in open arm after self-admin	0.7	0.8	2.3	0.4	0.6	0.2	0.7	-0.7	0.0	0.4	0.3	1.5	-1.5	-1.5
Bone: periosteal estimation	2.4	5.1	6.2	2.3	2.3	2.2	2.3	-2.3	2.2	2.0	2.3	2.5	-2.2	-2.2
Bone: periosteal perimeter	2.2	3.9	4.3	1.9	2.0	2.0	2.1	-2.1	2.0	1.8	1.9	1.9	-1.9	-1.9
Bone: post-yield work	1.7	2.5	3.9	1.7	1.7	1.7	1.6	-1.6	1.6	1.9	2.0	1.1	-1.1	-1.2
Progressive ratio test 1 active lever presses	0.1	0.1	0.5	-0.3	-0.1	0.1	0.3	-0.2	-0.1	-0.3	0.3	0.4	-0.7	-0.7
Progressive ratio test 1 breakpoint	0.2	0.2	0.7	-0.1	0.1	0.3	0.4	-0.4	0.0	-0.1	0.5	0.6	-0.9	-0.9
Progressive ratio test 1 inactive lever presses	0.5	0.7	0.8	0.7	0.9	0.9	0.8	-0.9	0.8	0.8	0.8	0.7	-0.9	-0.8
Progressive ratio test 2 active lever presses	0.1	0.2	0.3	-0.6	-0.5	-0.2	-0.3	0.3	-0.5	-0.5	-0.2	-0.5	0.3	0.3
Progressive ratio test 2 breakpoint	0.2	0.2	0.4	-0.6	-0.5	-0.3	-0.4	0.4	-0.5	-0.6	-0.3	-0.5	0.3	0.3
Progressive ratio test 2 inactive lever presses	0.8	1.4	2.4	1.1	1.2	1.6	1.2	-1.2	1.3	1.3	1.4	0.5	-0.8	-0.8
Incentive Sensitization - Responses	0.3	0.4	0.7	-0.5	-0.6	-0.5	-0.6	0.6	-0.4	-0.4	-0.5	-0.9	0.8	0.7
Incentive Sensitization - Breakpoint	0.3	0.4	0.8	-0.5	-0.6	-0.5	-0.7	0.7	-0.4	-0.4	-0.5	-0.9	0.8	0.8
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.6	-0.4	-0.5	-0.6	-0.3	0.3	-0.7	-0.8	0.1	0.0	-0.0	-0.0
Progressive ratio	0.2	0.4	1.4	0.1	-0.2	-0.1	-0.4	0.4	-0.0	-0.1	0.2	-0.9	1.2	1.1
Food seeking constrained by brief footshock	3.0	3.7	5.3	1.9	2.1	1.9	2.0	-1.9	1.9	2.1	2.3	1.5	-1.7	-1.7
Seeking ratio, punishment vs. effort	1.0	1.5	2.7	0.8	1.2	1.2	1.3	-1.3	1.2	1.0	0.8	1.2	-1.6	-1.6
Retroperitoneal fat weight	0.6	2.6	3.6	-1.8	-1.6	-1.9	-1.7	1.7	-1.7	-1.5	-1.9	-1.2	1.2	1.2
Reaction time number correct	0.1	0.2	0.5	-0.6	-0.4	-0.6	-0.4	0.4	-0.7	-0.4	-0.6	0.1	-0.3	-0.3
Reaction time mean minus median	0.1	0.1	0.3	0.2	0.3	0.2	0.3	-0.3	0.3	0.2	0.3	0.3	-0.5	-0.6
Reaction time mean minus median AUC	0.1	0.2	0.7	0.2	0.4	0.4	0.4	-0.4	0.5	0.3	0.3	0.5	-0.8	-0.8
Reaction time num false alarms	1.4	2.0	3.0	-1.4	-1.5	-1.5	-1.4	1.4	-1.5	-1.7	-1.5	-1.0	1.2	1.4
Reaction time num false alarms AUC	1.7	2.7	3.9	-1.6	-1.7	-1.8	-1.7	1.7	-1.8	-2.0	-1.5	-1.3	1.4	1.6
Reaction time trials correct on left	0.1	0.2	0.5	-0.6	-0.4	-0.6	-0.4	0.4	-0.7	-0.4	-0.6	0.1	-0.3	-0.3
Reaction time trials on left	0.1	0.2	0.5	-0.6	-0.5	-0.6	-0.4	0.4	-0.7	-0.4	-0.6	0.1	-0.3	-0.3
Reaction time mean	0.1	0.1	0.2	-0.2	-0.3	-0.5	-0.3	0.4	-0.3	-0.4	-0.1	-0.3	0.2	0.2
Reaction time mean AUC	0.2	0.3	0.6	-0.5	-0.5	-0.8	-0.6	0.6	-0.6	-0.7	-0.2	-0.5	0.3	0.4
Median of all reaction times	0.3	0.4	0.7	-0.5	-0.6	-0.8	-0.7	0.7	-0.7	-0.7	-0.4	-0.7	0.6	0.6
Reaction time omissions	0.4	0.6	1.7	-0.9	-1.0	-0.8	-0.7	0.7	-0.8	-1.3	-0.7	-0.6	0.5	0.5
Reaction time false alarm rate	1.0	1.4	2.4	-1.0	-1.2	-1.1	-1.2	1.2	-1.0	-1.3	-0.9	-1.1	1.4	1.6
Reaction time premature initiation rate	0.0	0.1	0.2	0.2	0.2	0.5	0.2	-0.2	0.4	0.1	0.3	-0.2	-0.0	0.1
Reaction time premature initiations	0.0	0.0	0.1	-0.2	-0.1	0.1	-0.0	0.0	0.0	-0.2	-0.0	-0.1	-0.2	-0.0
Std. dev. reaction times	0.0	0.1	0.2	0.1	0.2	0.1	0.2	-0.2	0.2	-0.1	0.3	0.2	-0.5	-0.5
Reaction time trials completed	0.1	0.2	0.5	-0.6	-0.5	-0.6	-0.4	0.4	-0.7	-0.4	-0.6	0.1	-0.3	-0.3
Reaction time trials AUC	0.2	0.4	0.9	-0.8	-0.7	-0.8	-0.6	0.6	-0.9	-0.7	-0.7	-0.0	-0.1	-0.1
Run reversals in cocaine runway, females	0.0	0.0	0.2	0.2	-0.1	-0.0	-0.1	0.1	-0.1	0.1	0.2	-0.2	0.3	0.4
Run reversals in cocaine runway, males	1.5	1.5	2.3	-1.5	-1.5	-1.4	-1.1	1.2	-1.4	-1.5	-0.5	-1.3	0.8	0.8
Latency to leave start box in cocaine runway	0.0	0.0	0.1	0.1	-0.2	-0.1	-0.1	0.1	-0.2	-0.2	-0.0	0.0	0.2	0.2
Latency to leave start box in cocaine runway, F	0.4	0.4	0.7	-0.8	-0.8	-0.6	-0.6	0.6	-0.8	-0.8	-0.6	-0.5	0.4	0.5
Latency to leave start box in cocaine runway, M	0.2	0.2	0.7	0.8	0.6	0.5	0.4	-0.4	0.6	0.6	0.2	0.5	-0.1	-0.1
Std. dev. time between licks in bursts	0.7	0.9	1.3	1.1	1.0	1.1	1.0	-1.0	1.1	1.1	0.8	0.8	-0.7	-0.8
Total sessions with >9 infusions	1.6	2.0	3.4	-1.9	-1.6	-1.6	-1.4	1.4	-1.8	-1.7	-1.3	-0.7	0.6	0.5
Short access day 1 total inactive lever presses	1.0	1.3	2.5	1.3	1.4	1.4	1.1	-1.2	1.3	1.6	0.9	0.6	-0.8	-0.8
Short access day 10 total inactive lever presses	2.2	5.5	8.0	2.8	2.5	2.6	2.4	-2.4	2.5	2.7	2.6	1.6	-1.5	-1.5
Short access day 1 total infusions	0.2	0.3	1.0	-0.2	0.2	0.2	0.5	-0.5	-0.1	0.2	-0.1	0.6	-0.9	-1.0
Short access day 10 total infusions	0.4	0.5	1.1	-1.1	-0.8	-0.7	-0.7	0.7	-1.0	-0.9	-0.4	-0.5	0.1	0.1
Short access total infusions	0.6	0.7	1.7	-1.3	-0.9	-0.8	-0.8	0.8	-1.2	-0.9	-1.0	-0.6	0.2	0.2
Short access day 1 locomotion	2.3	2.9	4.9	-1.8	-1.9	-1.9	-1.7	1.8	-2.2	-2.0	-1.6	-1.0	1.1	1.1
Short access day 10 total locomotion	0.4	0.7	2.0	1.0	0.7	0.4	0.8	-0.7	0.3	0.7	1.4	0.9	-0.9	-0.9
Short access total locomotion	0.8	0.9	2.2	-1.1	-1.0	-1.4	-0.9	1.0	-1.5	-1.1	-0.9	-0.2	0.1	0.1
One hour access (0.3 mA shock)	0.7	0.8	1.4	1.0	0.9	1.2	0.9	-0.9	1.0	0.9	0.8	0.6	-0.6	-0.6
Compulsive drug intake	2.1	2.5	4.2	1.4	2.0	1.3	1.4	-1.5	1.8	1.9	-0.2	1.7	-1.7	-1.7
One hour access (shock baseline)	0.0	0.1	0.2	-0.1	-0.3	0.2	-0.1	0.1	-0.2	-0.2	0.4	-0.4	0.3	0.3
Social response proportion	3.5	4.0	5.4	1.8	1.7	2.1	2.2	-2.1	1.8	1.2	2.1	2.0	-2.3	-2.3
Social responses	0.3	0.3	1.4	0.7	0.3	0.7	0.6	-0.6	0.5	0.1	1.2	0.3	-0.2	-0.3
Social time	1.6	2.2	4.2	1.9	1.4	1.9	1.4	-1.4	1.9	1.3	2.1	0.7	-0.6	-0.8
Soleus weight	0.4	1.1	2.5	-0.9	-1.0	-0.7	-1.0	1.0	-0.7	-0.7	-0.3	-1.6	1.5	1.5
Bone: stiffness	1.6	2.7	3.1	1.7	1.7	1.6	1.7	-1.7	1.7	1.6	1.7	1.6	-1.5	-1.5
Tibialis anterior weight	0.0	0.1	0.3	-0.3	-0.3	-0.5	-0.4	0.3	-0.5	-0.3	-0.6	-0.0	0.1	0.1
Time to tail flick, vehicle, before self-admin	0.5	0.5	1.3	-0.9	-0.7	-1.1	-0.6	0.7	-1.2	-0.7	-0.7	0.2	-0.2	-0.2
Time to tail flick, vehicle, after self-admin	1.0	1.4	2.4	1.2	1.2	1.3	1.3	-1.3	1.5	1.2	1.6	0.5	-0.6	-0.6
Time to tail flick, test, before self-admin	0.5	0.5	1.1	-0.6	-0.8	-0.8	-0.7	0.7	-1.1	-0.9	-0.7	-0.2	0.5	0.5
Time to tail flick, test, after self-admin	0.1	0.1	0.3	-0.4	-0.5	-0.4	-0.3	0.3	-0.5	-0.6	-0.2	-0.1	0.3	0.3
Delta time to tail flick, vehicle, before/after SA	0.9	0.9	1.4	1.1	1.0	1.1	1.0	-1.0	1.2	0.8	1.1	0.6	-0.5	-0.5
Delta time to tail flick, test, before/after SA	0.0	0.0	0.0	-0.2	-0.0	0.0	0.0	-0.1	0.1	-0.2	-0.1	-0.0	-0.1	-0.1
Tibia length	1.8	5.1	6.5	2.1	2.1	1.9	2.4	-2.3	1.9	2.0	2.5	2.4	-2.5	-2.5
Ambulatory time before self-admin	1.4	2.1	2.7	1.2	1.6	1.6	1.6	-1.6	1.6	1.3	1.2	1.2	-1.5	-1.5
Ambulatory time after self-admin	3.4	4.0	4.9	2.0	2.1	2.2	2.1	-2.1	2.1	1.9	2.2	1.8	-1.8	-1.8
Bone: tissue strength	4.6	4.6	5.5	2.3	2.3	1.9	2.1	-2.2	2.0	2.2	1.7	2.3	-2.2	-2.2
Total heroin consumption	0.7	0.8	1.5	0.7	0.9	0.5	0.9	-0.9	0.7	0.8	0.9	1.0	-1.2	-1.2
Bone: trabecular number	0.2	0.3	1.7	0.6	0.3	0.6	0.6	-0.5	0.4	0.2	1.3	0.5	-0.3	-0.4
Bone: trabecular spacing	1.5	2.0	2.6	1.5	1.6	1.4	1.4	-1.4	1.5	1.5	0.6	1.4	-1.5	-1.5
Bone: trabecular thickness	0.3	0.4	0.8	-0.9	-0.7	-0.8	-0.6	0.6	-0.8	-0.8	-0.5	-0.2	0.2	0.4
Bone: trabecular tissue density	2.0	3.0	3.7	-1.5	-1.7	-1.6	-1.9	1.8	-1.6	-1.6	-1.6	-1.7	1.9	1.9
Water consumed over 24 hours	0.3	0.4	1.1	0.2	0.3	0.0	0.6	-0.5	-0.0	0.1	0.6	1.0	-1.1	-1.0
Number of responses in last shaping day	0.4	0.4	0.7	0.3	0.3	0.9	0.8	-0.8	0.6	0.1	0.5	0.7	-0.8	-0.8