Dock1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS NM_001143858.1 0.11 0.08 2.0e-03 0 0 -0 -0 1.5e-01 3.6e-01 9.2e-01 9.4e-01
2 Adipose alternative TSS XM_063263800.1 0.11 0.07 1.7e-03 0 0 -0 -0 1.7e-01 2.8e-01 4.0e-01 9.8e-01
3 OFC mRNA stability Dock1 0.49 0.18 2.8e-04 0.19 0.17 0.21 0.22 3.1e-05 7.2e-05 1.2e-05 7.3e-06
4 Adipose gene expression Dock1 0.51 0.11 0.0e+00 0.2 0.23 0.24 0.22 7.6e-22 2.9e-25 6.3e-26 4.5e-24
5 IC gene expression Dock1 0.43 0.11 1.3e-06 0.19 0.08 0.15 0.16 2.2e-08 3.7e-04 8.9e-07 2.5e-07
6 NAcc gene expression Dock1 0.26 0.08 3.3e-14 0.08 0.09 0.11 0.1 1.4e-12 1.1e-13 1.6e-16 1.5e-15
7 PL gene expression Dock1 0.35 0.13 5.7e-11 0.11 0.04 0.12 0.12 6.4e-12 9.5e-06 1.6e-13 1.5e-12
8 IC intron excision ratio chr1_199099491_199119912 0.12 0.06 5.1e-03 0.04 0.05 0.03 0.04 1.2e-02 3.0e-03 3.1e-02 8.4e-03
9 pVTA gene expression Dock1 0.45 0.1 0.0e+00 0.22 0.25 0.25 0.26 3.7e-17 4.1e-20 2.4e-20 1.2e-20
10 BLA mRNA stability Dock1 0.08 0.05 9.3e-03 0.04 0.04 0.04 0.04 5.7e-03 2.4e-03 3.2e-03 5.0e-03
11 Adipose mRNA stability Dock1 0.39 0.1 0.0e+00 0.17 0.21 0.2 0.21 5.1e-19 1.2e-22 1.3e-21 5.6e-23
12 Liver gene expression Dock1 0.28 0.09 1.2e-15 0.11 0.1 0.1 0.1 2.5e-12 3.2e-11 9.2e-11 2.8e-11
13 Brain mRNA stability Dock1 0.35 0.12 2.5e-14 0.07 0.18 0.16 0.15 5.3e-07 2.8e-16 5.1e-15 1.5e-13
14 Brain gene expression Dock1 0.58 0.09 0.0e+00 0.18 0.35 0.33 0.33 2.1e-16 1.8e-33 9.6e-32 1.5e-31
15 LHb mRNA stability Dock1 0.33 0.15 9.5e-03 0.08 0.05 0.02 0.07 5.3e-03 2.6e-02 9.5e-02 1.2e-02
16 Liver mRNA stability Dock1 0.12 0.06 4.0e-09 0.03 0.07 0.07 0.06 1.6e-04 2.3e-08 4.6e-08 2.5e-07
17 PL isoform ratio NM_001143858.1 0.06 0.03 5.9e-04 0.01 0.03 0.02 0.02 1.5e-02 1.9e-04 1.9e-03 4.7e-03
18 PL intron excision ratio chr1_198996980_199000423 0.04 0.03 9.6e-03 0.02 0.02 0 0.01 2.6e-03 2.4e-03 1.6e-01 3.8e-02
19 PL isoform ratio XM_063263800.1 0.06 0.03 5.0e-04 0.01 0.03 0.02 0.02 1.4e-02 1.5e-04 1.2e-03 3.4e-03
20 LHb gene expression Dock1 0.5 0.14 1.3e-04 0.06 0.08 0.06 0.1 1.6e-02 5.4e-03 1.8e-02 2.8e-03
21 PL mRNA stability Dock1 0.07 0.05 2.2e-03 0.01 0.03 0.04 0.02 4.8e-02 7.8e-04 7.0e-05 3.9e-03
22 NAcc mRNA stability Dock1 0.07 0.04 1.3e-04 0.03 0.03 0.04 0.03 1.3e-05 2.3e-05 5.2e-07 2.4e-05
23 BLA gene expression Dock1 0.24 0.13 3.3e-03 0.01 0.02 0.03 0.03 6.0e-02 3.2e-02 1.7e-02 1.5e-02
24 pVTA mRNA stability Dock1 0.12 0.05 4.5e-07 0.08 0.1 0.1 0.1 1.0e-06 2.9e-08 8.0e-09 2.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.61.14.81.6-1.6-0.6-0.5-0.10.10.9-0.2-0.4-1.21.10.5-1.3-0.5-0.00.6-0.9-1.00.8-1.42.21.1-2.1-0.0
Area under the delay curve0.10.10.6-0.10.10.2-0.2-0.1-0.2-0.7-0.50.2-0.10.50.20.1-0.20.8-0.7-0.00.10.00.0-0.50.1-0.20.2
BMI with tail1.96.618.8-0.90.90.2-2.7-3.3-3.6-3.1-1.04.31.81.8-3.13.13.7-2.01.42.11.5-2.03.9-3.1-1.52.5-2.7
BMI without tail0.42.06.7-0.40.40.3-1.8-1.9-1.7-1.3-0.72.60.71.7-1.81.62.0-1.31.31.00.6-1.02.1-1.0-0.10.8-1.8
Body weight1.04.413.4-0.50.5-0.7-2.0-3.0-3.1-2.9-1.43.71.01.5-2.42.43.5-1.91.01.20.7-1.13.2-1.9-1.02.1-1.8
Weight adjusted by age0.20.72.40.1-0.10.0-0.9-1.0-1.5-0.7-0.11.30.50.4-1.31.01.4-0.90.70.70.5-0.71.1-0.4-0.60.4-1.0
Bone surface1.32.76.52.5-2.5-2.1-1.3-1.1-0.4-0.6-1.80.1-2.52.00.4-2.2-0.7-0.1-0.6-1.9-2.11.9-1.32.40.6-1.80.8
Bone volume1.22.56.82.6-2.6-1.9-1.1-0.8-0.2-0.2-1.4-0.2-2.31.80.6-2.1-0.80.1-0.4-1.8-1.91.7-1.62.60.8-2.10.6
Breakpoint value in progressive ratio session0.71.33.1-0.80.8-0.21.61.41.40.6-0.2-1.6-0.6-1.01.7-1.2-1.71.5-1.8-1.1-0.71.1-1.20.20.30.01.7
Number of licking bursts0.20.62.0-0.30.30.61.11.30.60.50.9-1.40.4-1.01.00.0-0.91.3-0.60.30.7-0.3-1.0-0.4-0.1-0.20.6
Context. condit. distance diff. score1.21.55.82.0-2.0-0.9-2.4-1.9-1.9-1.3-1.01.5-0.82.1-0.9-0.00.9-0.00.2-0.1-0.30.1-0.00.8-0.2-0.9-0.6
Locomotion velocity, session 10.10.20.60.3-0.30.2-0.1-0.1-0.8-0.00.60.10.5-0.3-0.30.50.6-0.10.50.50.5-0.50.0-0.2-0.6-0.0-0.5
Locomotion distance, session 10.50.72.2-0.90.91.21.41.11.11.51.2-0.70.7-0.60.50.3-0.2-0.11.20.40.3-0.5-0.50.31.0-0.6-0.4
Locomotion velocity, session 20.10.10.30.2-0.2-0.50.50.0-0.3-0.10.0-0.2-0.0-0.50.1-0.00.4-0.40.1-0.2-0.20.2-0.10.2-0.20.20.1
Locomotion distance, session 20.70.92.2-1.41.41.21.30.80.40.91.3-0.21.5-1.3-0.01.30.9-0.41.01.01.0-1.00.5-0.80.20.7-0.6
Locomotion velocity, session 30.60.72.30.8-0.8-1.0-0.8-1.0-0.5-1.2-1.50.7-1.11.3-0.1-0.8-0.1-0.0-0.7-1.0-1.11.00.10.3-0.1-0.10.4
Locomotion distance, session 31.41.66.60.2-0.2-1.8-0.0-1.2-0.1-1.6-2.60.8-1.71.40.6-1.00.30.2-1.4-1.9-2.22.00.21.00.90.11.3
Stereotopy head waving bouts, day 31.21.45.31.5-1.5-0.60.20.91.00.80.2-1.6-1.3-0.40.7-2.3-2.30.4-0.6-1.2-1.01.2-1.81.3-0.3-1.40.8
Stereotopy head waving duration, day 30.80.94.40.9-0.90.10.11.00.91.00.3-1.4-0.9-0.10.7-1.7-2.10.7-0.5-0.7-0.40.6-1.50.90.0-1.40.6
Locomotion velocity, session 71.61.75.82.0-2.0-2.4-1.6-1.7-1.6-2.1-1.40.9-1.10.5-1.1-1.00.3-1.1-0.7-0.8-0.80.80.5-0.1-1.80.70.1
Locomotion distance, session 71.21.55.41.4-1.4-2.3-1.4-1.9-1.5-2.2-1.81.3-1.10.7-0.7-0.41.1-0.8-0.9-1.0-1.11.00.80.1-1.00.90.3
Stereotopy head waving bouts, day 70.91.04.60.9-0.90.90.41.00.71.50.8-1.2-0.60.30.5-1.3-1.70.60.5-0.4-0.30.3-1.51.30.6-2.1-0.0
Stereotopy head waving duration, day 70.60.73.51.4-1.40.8-0.60.2-0.21.00.7-0.4-0.40.8-0.3-0.9-1.10.11.00.10.1-0.2-1.00.90.1-1.9-0.7
Locomotion velocity, session 80.60.71.91.4-1.4-1.3-1.3-0.9-1.1-1.1-1.10.3-0.90.70.0-0.40.20.5-1.1-0.6-0.50.6-0.30.4-0.50.00.6
Locomotion distance, session 80.20.31.01.0-1.0-0.5-0.7-0.7-0.8-0.6-0.50.4-0.50.80.1-0.00.50.6-0.2-0.4-0.40.3-0.50.60.2-0.70.1
Degree of sensitization distance0.50.51.60.5-0.50.1-0.7-0.2-0.9-0.20.90.10.8-0.7-0.90.70.5-0.50.51.01.2-1.00.5-0.8-1.30.6-0.8
Degree of sensitization stereotypy0.40.42.50.8-0.80.9-0.00.40.01.00.7-0.6-0.10.40.1-0.5-0.80.60.60.10.1-0.2-1.00.80.4-1.6-0.3
Conditioned locomotion0.10.21.10.4-0.40.5-0.00.20.20.30.3-0.4-0.10.30.2-0.2-0.40.70.20.00.1-0.1-0.70.50.4-1.0-0.1
Cocaine response after cond. corrected1.82.66.10.9-0.9-0.0-2.4-2.0-2.4-0.90.12.40.91.0-2.51.62.2-1.92.01.61.2-1.61.9-0.8-1.00.6-2.2
Cocaine response after cond. not corrected1.82.66.30.9-0.9-0.3-2.2-1.9-2.4-1.10.22.21.00.5-2.51.52.1-1.91.61.51.3-1.52.0-1.1-1.51.0-2.0
Cocaine response before conditioning0.40.52.00.0-0.0-0.61.00.80.70.00.1-1.2-0.3-1.40.6-0.8-0.90.3-1.1-0.6-0.30.6-0.4-0.2-0.80.51.0
Saline control response2.94.010.2-1.81.80.12.41.83.21.2-1.3-1.7-1.70.12.7-2.1-2.21.7-1.5-2.4-2.52.4-1.62.02.8-1.32.2
Bone: connectivity density0.71.13.41.5-1.5-1.2-0.7-0.40.20.2-0.9-0.1-1.51.10.3-1.6-0.6-0.50.0-1.2-1.41.2-0.91.80.7-1.40.3
Bone: cortical apparent density0.30.52.7-0.70.7-0.01.30.90.50.20.5-1.00.4-1.60.60.3-0.10.8-0.90.00.30.0-0.2-0.5-0.50.60.9
Bone: cortical area0.71.22.50.7-0.7-0.0-1.1-0.8-1.3-0.50.90.81.0-0.6-1.61.01.2-1.51.21.21.3-1.21.1-1.1-1.61.1-1.4
Bone: cortical porosity0.70.82.50.6-0.6-0.10.40.60.60.2-0.4-1.1-0.90.51.2-0.8-1.11.6-1.1-0.8-0.50.7-1.50.80.7-0.91.1
Bone: cortical porosity0.30.31.60.3-0.30.90.20.60.20.50.5-0.70.10.30.60.1-0.61.3-0.10.30.5-0.3-1.00.20.5-0.80.1
Bone: cortical thickness1.72.85.60.4-0.4-0.3-1.2-1.2-1.9-0.91.11.41.7-1.2-2.31.82.2-2.21.41.81.8-1.82.1-2.0-2.42.2-1.8
Bone: cortical thickness0.70.82.41.0-1.0-1.3-0.9-1.2-1.6-1.3-0.40.90.1-0.1-1.00.61.3-1.00.10.30.3-0.30.9-0.5-1.41.1-0.4
Bone: cortical tissue density0.30.52.4-0.70.7-0.21.30.80.4-0.00.3-0.90.3-1.50.60.2-0.00.8-1.0-0.10.20.1-0.2-0.5-0.50.71.0
Condit. Reinf. active minus inactive responses1.51.76.1-2.52.50.82.31.92.21.40.3-1.30.3-1.41.5-0.2-0.90.8-0.7-0.5-0.50.6-0.2-0.01.50.31.1
Condit. Reinf. active-inactive response ratio1.51.64.4-1.81.80.72.11.92.11.60.3-1.6-0.1-1.11.7-0.6-1.31.3-0.9-0.7-0.60.7-0.80.51.5-0.31.3
Condit. Reinf. active responses1.01.36.1-2.52.51.31.71.41.51.40.9-0.51.1-1.30.50.80.1-0.30.70.40.3-0.40.5-0.41.30.5-0.0
Condit. Reinf. inactive responses0.70.92.8-1.21.21.40.50.50.31.21.20.21.2-0.3-0.31.20.8-0.81.71.20.9-1.20.5-0.20.8-0.0-0.9
Incentive salience index mean1.11.46.0-2.42.41.22.01.71.71.41.0-1.01.0-1.80.80.5-0.40.00.10.30.3-0.20.3-0.71.00.70.3
Condit. Reinf. lever presses0.91.44.0-1.41.41.81.11.41.01.62.0-0.71.6-1.6-0.20.8-0.2-0.81.51.21.3-1.20.3-0.80.20.3-0.9
Condit. Reinf. active minus inactive responses0.60.92.1-0.20.20.41.21.11.41.40.1-1.2-0.60.11.3-0.9-1.10.8-0.2-0.8-0.80.8-1.21.31.5-1.00.8
Condit. Reinf. active-inactive response ratio0.40.72.20.4-0.40.20.40.40.70.6-0.4-0.5-0.91.11.0-0.9-0.80.8-0.1-0.8-0.90.7-1.21.31.5-1.50.5
Condit. Reinf. active responses0.30.51.8-0.90.90.41.40.91.11.00.1-0.7-0.1-0.21.1-0.2-0.40.3-0.1-0.4-0.50.5-0.40.61.2-0.10.6
Condit. Reinf. inactive responses0.30.52.2-1.51.50.51.00.50.50.50.40.00.8-0.80.20.70.4-0.40.20.30.3-0.30.7-0.60.31.1-0.0
Condit. Reinf. lever presses0.50.71.8-0.70.7-0.11.10.61.40.2-0.7-0.7-0.70.11.3-0.8-0.90.7-1.1-1.1-1.11.1-0.60.51.1-0.11.2
Condit. Reinf. lever reinforcers received0.40.62.2-1.21.20.21.50.81.30.9-0.2-0.6-0.2-0.21.1-0.4-0.50.3-0.4-0.7-0.80.7-0.30.61.30.10.8
Conditioned reinforcement - actives1.35.319.8-4.54.54.23.02.31.81.42.2-0.73.0-1.81.22.60.21.90.42.12.1-2.00.4-2.41.30.5-0.2
Conditioned reinforcement - inactives0.82.16.1-2.52.51.91.91.61.20.81.6-0.91.9-2.10.71.70.31.0-0.01.31.5-1.20.5-1.60.21.10.1
Conditioned locomotion5.98.831.9-5.65.65.04.44.03.52.92.5-2.32.7-2.62.81.7-1.53.5-0.41.31.5-1.2-0.8-1.72.2-0.20.9
Patch foraging indifference point 0 sec0.61.64.71.2-1.2-1.30.30.10.6-0.1-1.1-0.7-1.90.80.8-2.2-1.40.0-0.4-1.8-1.91.8-1.31.80.8-1.60.9
Patch foraging indifference point AUC0.10.20.7-0.50.50.30.70.50.80.70.2-0.5-0.2-0.20.4-0.3-0.50.10.1-0.3-0.30.3-0.30.50.6-0.20.2
Delay disc. indifference point, 0s delay0.91.04.90.8-0.8-0.5-1.3-1.1-1.1-1.4-1.81.0-1.22.20.1-0.40.01.0-0.9-0.8-0.90.8-0.00.30.4-0.80.3
Delay disc. indifference point, 16s delay0.00.10.20.1-0.1-0.10.10.10.1-0.50.0-0.20.0-0.3-0.0-0.0-0.30.2-0.40.10.2-0.10.0-0.5-0.50.20.1
Delay disc. indifference point, 2s delay0.40.41.70.1-0.10.90.50.90.70.50.4-0.9-0.20.30.8-0.7-1.31.1-0.1-0.2-0.10.1-1.10.20.6-1.20.3
Delay disc. indifference point, 24s delay0.50.72.7-1.01.00.6-0.1-0.4-0.6-1.10.00.81.0-0.2-0.51.40.80.5-0.31.01.1-0.91.1-1.6-0.71.1-0.4
Delay disc. indifference point, 4s delay0.50.52.3-0.20.2-0.4-0.3-0.4-0.6-1.4-1.30.3-0.61.00.50.0-0.11.2-1.5-0.5-0.40.50.1-0.60.10.20.9
Delay disc. indifference point, 8s delay0.10.10.7-0.40.40.40.40.50.40.0-0.0-0.3-0.1-0.10.6-0.1-0.40.9-0.6-0.10.00.1-0.4-0.00.4-0.30.4
Indifference point function ln k0.41.13.21.1-1.10.1-1.3-1.1-1.8-1.10.51.10.80.4-1.31.21.3-0.61.01.21.2-1.20.7-0.9-1.00.3-1.3
Indifference point function log k0.41.13.21.1-1.10.1-1.3-1.1-1.8-1.10.51.10.80.4-1.31.21.3-0.61.01.21.2-1.20.7-0.9-1.00.3-1.3
Patch foraging total patch changes 0 sec0.61.64.51.4-1.4-1.50.2-0.00.5-0.3-1.3-0.6-2.00.80.8-2.1-1.20.1-0.6-1.9-1.91.8-1.21.90.7-1.51.0
Patch foraging total patch changes 12 sec1.92.67.61.0-1.0-1.70.60.41.10.3-1.4-1.2-2.40.51.3-2.8-1.90.4-1.1-2.5-2.52.5-1.52.30.9-1.51.6
Patch foraging total patch changes 18 sec0.20.51.50.8-0.8-0.4-0.7-0.7-0.40.0-0.50.7-0.71.2-0.7-0.50.1-1.21.2-0.3-0.60.20.21.00.6-0.7-0.8
Patch foraging total patch changes 24 sec0.10.31.0-0.20.2-0.40.3-0.10.3-0.0-0.80.2-0.70.60.2-0.5-0.0-0.80.4-0.7-1.00.70.00.90.9-0.30.1
Patch foraging total patch changes 6 sec2.03.39.50.6-0.6-2.20.4-0.11.3-0.7-2.6-0.5-2.91.11.3-3.0-1.90.1-1.7-2.9-3.12.9-1.02.01.0-1.11.9
Patch foraging time to switch 0 sec0.10.31.0-0.60.60.10.50.90.90.70.1-0.8-0.3-0.70.5-0.8-1.00.2-0.4-0.5-0.40.5-0.40.10.3-0.10.5
Patch foraging water rate 0 sec0.20.71.90.9-0.9-1.2-0.8-1.4-0.9-1.2-1.21.2-0.81.2-0.6-0.20.9-0.90.2-0.6-0.90.60.50.50.1-0.0-0.1
Patch foraging water rate 12 sec0.31.12.80.5-0.5-0.4-1.4-1.5-1.4-1.2-0.51.70.51.1-1.11.31.6-1.30.70.80.6-0.81.3-0.9-0.21.0-1.0
Patch foraging water rate 18 sec0.81.75.8-0.50.5-0.2-1.1-1.7-1.1-1.1-0.62.40.81.0-1.51.42.2-2.21.40.90.3-0.82.1-0.9-0.21.2-1.5
Patch foraging water rate 24 sec0.60.82.60.7-0.7-0.6-1.6-1.5-0.8-1.1-1.01.6-0.21.6-0.80.61.3-0.70.30.0-0.2-0.00.8-0.10.30.2-0.7
Patch foraging water rate 6 sec0.20.30.7-0.60.60.40.1-0.5-0.0-0.5-0.20.80.40.6-0.40.70.8-0.60.70.30.1-0.30.6-0.30.50.3-0.5
Seeking ratio, delayed vs. immediate footshock0.10.21.0-0.10.1-0.80.50.20.00.10.2-0.40.2-1.00.20.00.3-0.5-0.1-0.0-0.00.10.30.1-0.51.00.4
Distance traveled before self-admin0.81.75.6-2.22.21.92.21.52.01.30.1-0.80.20.31.60.0-1.01.5-0.2-0.2-0.40.3-0.90.32.4-1.10.7
Distance traveled after self-admin1.12.07.5-2.72.71.31.60.80.90.41.10.12.0-1.7-0.11.91.0-0.70.61.31.3-1.31.3-1.80.11.7-0.4
Extensor digitorum longus weight0.41.53.81.8-1.8-1.3-2.0-1.8-1.6-0.9-0.91.5-0.91.5-1.3-0.31.1-1.71.3-0.3-0.70.30.51.1-0.2-0.6-1.0
Bone: elastic displacement0.20.31.01.0-1.0-0.8-0.7-0.6-0.5-0.4-0.40.3-0.50.2-0.4-0.50.1-0.50.0-0.4-0.40.40.10.4-0.60.1-0.1
Bone: elastic work0.60.82.60.6-0.60.2-1.4-1.1-1.1-0.20.11.30.40.9-1.40.61.1-1.41.60.80.5-0.80.9-0.1-0.20.1-1.5
Bone: endosteal estimation0.30.85.90.8-0.80.2-1.3-0.9-0.5-0.0-0.91.0-0.82.4-0.2-0.30.10.00.8-0.3-0.70.3-0.21.31.3-1.5-0.7
Bone: endosteal perimeter0.40.93.70.7-0.70.7-0.20.70.91.00.0-0.9-0.91.20.9-1.2-1.71.00.1-0.5-0.50.5-1.51.21.2-1.90.1
Epididymis fat weight0.20.94.3-0.10.1-0.2-0.9-1.3-1.6-0.8-0.31.50.70.5-1.01.62.1-0.60.60.90.7-0.91.2-0.5-0.20.9-0.8
Delta time in closed arm before/after self-admin0.70.72.11.4-1.40.5-0.70.5-0.00.80.8-1.1-0.20.20.3-0.4-1.01.3-0.30.30.6-0.4-1.40.7-0.1-1.30.2
Delta time in open arm before/after self-admin0.40.51.41.1-1.1-1.0-0.6-0.7-0.3-0.4-0.60.5-0.70.6-0.5-0.9-0.1-1.20.5-0.7-0.90.70.20.6-0.2-0.3-0.4
Diff in mean of infusions in LGA sessions0.10.21.1-0.10.1-0.30.10.1-0.3-0.30.2-0.20.4-1.0-0.10.30.20.2-0.70.30.5-0.20.3-0.7-1.10.80.2
Delay discount exponential model param0.10.10.90.3-0.3-0.2-0.1-0.00.00.70.5-0.10.1-0.3-0.4-0.00.3-0.90.80.10.0-0.10.10.5-0.10.1-0.4
Extinction: sum of active levers before priming0.50.83.7-1.11.1-0.21.61.10.50.20.4-1.20.2-1.90.8-0.3-0.70.9-1.3-0.4-0.10.5-0.3-0.3-0.90.71.2
Active lever presses in extinction session 62.72.77.0-2.62.62.22.62.62.22.52.0-1.91.3-2.31.20.2-1.10.80.40.50.6-0.5-0.6-0.21.10.00.4
Bone: final force0.30.51.8-0.50.50.2-0.0-0.2-0.10.30.50.50.8-0.5-0.80.81.0-1.41.20.70.5-0.71.0-0.50.00.6-0.9
Bone: final moment0.40.72.4-0.40.40.4-0.1-0.2-0.20.50.80.61.0-0.5-1.01.01.1-1.51.50.90.7-0.91.0-0.5-0.00.5-1.2
Food consumed during 24 hour testing period0.40.73.2-0.60.61.80.20.60.31.01.5-0.11.2-0.5-0.40.80.1-0.21.21.21.2-1.20.1-0.6-0.0-0.2-1.0
Glucose0.50.81.70.0-0.0-0.21.10.50.80.5-0.6-0.7-1.00.21.1-1.1-0.71.1-0.8-1.3-1.31.3-1.11.31.1-1.11.0
Heart weight0.30.52.4-0.90.90.10.00.3-0.10.10.50.01.0-0.9-0.21.20.7-0.3-0.00.91.0-0.80.9-1.1-0.41.6-0.2
Delay discount hyperbolic model param0.20.21.10.0-0.0-0.10.00.00.00.80.6-0.00.4-0.6-0.50.20.4-1.10.90.30.2-0.30.30.3-0.20.4-0.5
Intermittent access intake day 1-15 change0.10.31.5-0.80.81.20.50.2-0.2-0.0-0.10.20.30.80.60.60.11.2-0.00.20.2-0.2-0.40.01.1-0.80.1
Intermittent access intake escalation0.10.31.8-0.70.71.30.60.4-0.10.30.20.00.40.50.50.50.11.00.30.30.2-0.3-0.50.11.0-0.9-0.1
Intermittent access intake escalation 20.10.20.9-0.90.90.90.50.1-0.5-0.30.00.30.40.10.20.50.21.0-0.10.30.3-0.30.0-0.50.2-0.3-0.0
Intermitt. access day 1 inactive lever presses0.00.61.9-0.00.0-0.01.10.90.5-0.10.3-1.3-0.2-1.10.8-0.8-1.21.4-1.2-0.5-0.20.5-0.7-0.2-0.5-0.10.9
Intermitt. access day 15 inactive lever presses0.20.84.1-0.60.6-0.6-0.1-1.1-1.4-2.0-1.41.3-0.20.4-0.40.20.60.4-1.2-0.4-0.40.51.0-1.2-0.81.00.3
Intermitt. access escalation Index0.20.51.90.0-0.00.7-0.6-0.1-0.3-0.00.90.21.0-0.2-0.61.00.4-0.40.61.31.4-1.30.5-1.0-0.60.6-0.8
Intermittent access day 1 total infusions0.92.67.0-2.62.62.62.32.42.62.11.5-1.71.1-1.41.70.4-1.31.8-0.10.50.6-0.5-0.9-0.51.3-0.50.6
Intermittent access day 15 total infusions1.02.59.4-2.72.73.12.12.01.61.51.6-1.11.7-1.11.31.3-0.51.80.21.21.3-1.2-0.4-1.11.1-0.30.1
Intermittent access terminal intake (last 3 days)1.52.78.9-3.03.02.72.62.21.81.61.3-1.31.4-1.31.81.1-0.62.1-0.30.80.9-0.7-0.6-0.71.5-0.40.7
Intermittent access total infusions2.73.211.5-3.43.43.12.72.42.31.91.6-1.41.6-1.51.71.1-0.81.80.10.90.9-0.8-0.5-0.91.6-0.30.4
Intermittent access day 1 locomotion1.52.711.2-3.33.33.02.01.71.61.51.6-0.52.0-1.50.61.5-0.10.70.81.31.2-1.20.5-1.50.80.5-0.4
Intermittent access day 15 total locomotion0.62.38.7-3.03.02.22.71.92.31.70.9-1.01.1-1.11.50.7-0.40.80.40.20.0-0.1-0.3-0.22.1-0.20.4
Intermittent access total locomotion3.03.513.0-3.63.63.53.02.42.42.21.6-1.11.6-1.21.60.9-0.81.50.70.70.5-0.6-0.4-0.62.1-0.80.1
Intermittent access standard deviation0.10.41.9-1.41.40.90.90.2-0.3-0.30.00.30.5-0.30.30.50.21.2-0.60.20.2-0.10.1-0.70.1-0.20.1
Left kidney weight0.43.27.7-0.30.30.4-1.7-1.8-2.4-2.2-0.02.41.60.6-2.12.42.2-1.20.91.91.8-1.92.5-2.8-1.81.9-1.8
Right kidney weight0.64.08.2-1.21.21.3-0.7-0.8-1.8-0.71.51.72.7-1.1-2.22.82.3-1.61.82.62.5-2.52.6-2.9-1.92.2-2.3
Cocaine induced anxiety0.20.62.2-0.90.9-0.21.20.60.9-0.2-0.8-0.6-0.40.01.30.2-0.11.1-1.4-0.5-0.40.5-0.40.11.10.41.5
Post-drug Anxiety0.50.54.0-0.60.60.50.50.41.20.7-0.6-0.2-0.41.11.10.3-0.00.8-0.3-0.3-0.40.3-0.50.82.0-0.50.7
Baseline Anxiety0.61.03.61.6-1.6-0.1-1.9-1.2-0.70.10.21.1-0.01.3-1.30.20.6-1.41.50.50.3-0.60.40.4-0.4-0.5-1.5
Tail length0.10.63.11.0-1.0-0.20.10.20.50.90.1-0.5-0.80.60.5-0.8-0.30.00.6-0.6-0.70.5-1.21.81.0-1.50.1
Length with tail0.00.10.2-0.10.1-0.50.4-0.1-0.0-0.3-0.30.1-0.3-0.10.20.10.4-0.1-0.2-0.3-0.30.30.00.30.10.10.3
Length without tail0.31.35.6-1.71.7-0.40.6-0.6-0.9-1.4-0.51.11.0-1.0-0.51.61.7-0.5-0.60.50.5-0.41.8-1.7-0.82.40.2
Times rat made contact with spout1.71.96.2-1.31.32.51.72.11.61.81.3-1.70.6-0.31.70.2-1.42.3-0.20.40.5-0.4-1.60.11.4-1.50.5
Lifetime Intake3.64.413.0-3.63.63.63.23.02.82.62.2-1.91.9-1.92.01.0-1.11.90.41.01.1-1.0-0.9-0.71.8-0.70.4
Liver weight, left1.11.95.91.1-1.1-1.8-1.0-1.7-0.9-1.5-2.41.4-1.82.30.1-0.90.6-0.5-0.4-1.6-2.01.60.11.61.1-0.80.4
Liver weight, right0.71.13.50.5-0.5-0.1-1.5-1.6-1.3-0.7-0.51.90.21.4-1.50.81.4-1.71.50.70.3-0.71.2-0.10.10.1-1.4
Locomotor activity0.50.93.7-1.91.90.71.00.40.80.40.40.31.0-0.9-0.21.11.1-1.20.80.50.3-0.41.1-0.60.61.2-0.3
Locomotor testing distance0.82.15.6-2.42.41.81.20.60.40.81.30.42.0-1.2-0.62.21.6-1.21.71.51.3-1.51.5-1.30.61.4-1.1
Locomotor testing rearing0.51.76.7-2.62.61.12.01.72.01.40.8-1.01.1-1.61.01.10.20.1-0.10.40.4-0.40.4-0.61.31.20.6
Locomotion in novel chamber1.41.98.6-2.92.91.50.5-0.3-0.1-0.1-0.21.61.50.5-0.32.11.6-0.30.81.10.7-1.02.0-1.51.21.4-0.8
Locomotion in novel chamber post-restriction0.10.41.7-0.20.2-1.1-0.4-0.7-0.4-0.1-0.70.7-0.3-0.1-0.5-0.00.8-1.30.2-0.3-0.60.31.00.5-0.11.00.0
Fecal boli incidents, locomotor time 10.20.51.00.4-0.4-0.2-0.00.00.60.2-0.6-0.4-0.90.80.9-0.8-0.60.8-0.6-0.8-0.80.8-1.00.90.8-1.00.7
Change in fecal boli incidents, locomotor task0.40.41.6-1.11.1-0.01.11.00.40.90.3-0.80.2-1.20.6-0.0-0.30.3-0.5-0.10.10.1-0.00.00.10.70.6
Time >=10cm from walls, locomotor time 12.22.78.1-0.30.31.71.82.51.92.11.2-2.7-0.5-0.82.0-1.6-2.82.4-0.8-0.6-0.20.5-2.51.00.8-2.01.2
Bouts of movement, locomotor time 10.60.82.31.1-1.1-1.5-0.9-1.0-1.0-1.4-1.40.4-0.91.00.1-0.10.40.6-1.5-0.7-0.50.7-0.10.0-0.40.30.8
Total resting periods, locomotor time 10.50.61.71.1-1.1-1.3-1.0-0.9-0.9-1.1-1.10.4-0.70.90.10.10.50.5-1.2-0.4-0.30.4-0.00.1-0.30.30.7
Rest time, locomotor task time 10.10.21.10.3-0.30.5-0.10.60.71.10.9-0.60.4-0.3-0.00.3-0.3-0.10.30.60.7-0.6-0.1-0.20.10.2-0.2
Distance moved, locomotor task time 10.20.73.2-0.60.60.00.90.60.5-0.4-0.6-0.7-0.6-0.01.3-0.5-0.71.8-1.4-0.9-0.70.9-0.90.20.5-0.71.2
Vertical activity count, locomotor time 10.21.44.6-1.21.21.42.11.81.11.00.6-1.50.1-0.61.7-0.2-1.12.1-0.7-0.3-0.10.3-1.50.21.0-1.20.9
Time >=10cm from walls, locomotor time 20.51.44.70.0-0.00.41.41.81.51.20.9-2.2-0.3-1.51.5-1.2-1.91.4-1.0-0.6-0.20.6-1.60.40.0-0.61.2
Bouts of movement, locomotor time 20.92.89.22.2-2.2-2.7-2.2-2.5-2.4-3.0-1.91.6-1.20.8-1.3-0.60.9-0.8-1.4-0.8-0.60.80.8-0.5-2.61.30.2
Total resting periods, locomotor time 20.62.46.92.1-2.1-2.3-2.3-2.3-2.5-2.6-1.31.6-0.70.6-1.5-0.11.2-1.0-0.9-0.2-0.00.20.9-0.7-2.61.4-0.2
Rest time, locomotor task time 20.20.41.31.1-1.1-0.7-0.9-0.5-0.8-0.10.30.00.2-0.2-0.70.30.4-0.2-0.10.50.7-0.50.2-0.3-1.10.4-0.3
Distance moved, locomotor task time 21.21.54.1-0.90.90.41.51.41.50.3-0.7-1.4-0.9-0.01.9-1.1-1.52.0-1.6-1.3-1.21.3-1.30.51.4-0.91.6
Vertical activity count, locomotor time 20.81.84.6-1.11.11.32.12.01.91.30.3-1.7-0.3-0.42.0-0.8-1.61.6-0.6-0.8-0.70.8-1.60.61.8-1.21.1
Light reinforcement 10.21.03.00.2-0.2-1.30.3-0.20.1-0.8-1.4-0.3-1.40.31.0-1.3-0.90.8-1.7-1.6-1.51.6-0.70.40.10.01.4
Light reinforcement 20.40.92.20.3-0.3-0.80.60.10.2-0.4-1.0-0.6-1.20.20.9-1.5-1.11.2-1.4-1.5-1.41.5-1.00.60.1-0.51.2
Bone: marrow area0.30.85.40.7-0.70.3-1.3-0.9-0.50.1-0.81.0-0.72.3-0.3-0.20.2-0.11.0-0.1-0.60.1-0.11.21.2-1.5-0.8
Bone: maximum diameter0.20.30.70.7-0.70.2-0.7-0.2-0.6-0.00.70.10.5-0.2-0.70.30.1-0.50.70.70.8-0.70.1-0.5-0.90.2-0.8
Bone: maximum force0.10.21.50.0-0.00.7-0.10.20.20.80.60.10.30.3-0.30.20.0-0.51.20.50.3-0.5-0.10.20.5-0.7-0.8
Bone: maximum moment0.20.42.30.0-0.00.9-0.10.30.11.00.90.10.50.2-0.40.30.1-0.61.50.70.5-0.7-0.00.10.5-0.7-1.0
Mean time between licks in bursts0.10.82.20.3-0.3-1.00.8-0.00.4-0.4-1.1-0.3-1.10.61.0-0.9-0.20.6-0.8-1.3-1.51.4-0.71.21.1-0.61.2
Mean num. licks in bursts0.10.31.6-0.60.60.80.00.10.60.8-0.30.3-0.30.90.2-0.2-0.20.10.6-0.3-0.70.3-0.10.91.3-0.9-0.2
Cd content in liver0.60.71.8-0.50.51.30.71.20.91.40.8-1.10.1-0.10.8-0.3-1.11.10.20.10.1-0.1-1.10.51.0-1.10.2
Co content in liver0.91.13.2-0.30.3-0.1-0.6-1.0-1.6-1.3-0.11.30.9-0.1-1.11.51.8-0.80.51.00.9-0.91.6-1.3-1.11.5-0.8
Cu content in liver0.70.81.90.3-0.30.5-0.6-0.7-1.1-0.40.80.81.1-0.1-1.01.41.3-0.31.01.31.3-1.30.8-0.8-0.80.3-1.1
Fe content in liver0.10.21.10.3-0.3-0.9-0.2-0.2-0.1-0.3-0.10.1-0.1-0.7-0.4-0.20.3-1.1-0.0-0.1-0.10.20.5-0.0-0.60.7-0.0
K content in liver1.00.94.21.2-1.2-0.9-1.4-1.5-1.6-2.1-1.11.3-0.41.4-0.60.20.7-0.1-0.3-0.0-0.10.00.5-0.4-0.90.2-0.2
Mg content in liver1.11.23.91.2-1.2-1.0-1.5-1.6-2.0-2.0-0.71.4-0.00.6-1.20.41.1-0.70.00.40.4-0.41.1-0.8-1.60.8-0.6
Mn content in liver1.31.53.81.9-1.9-1.8-1.3-1.3-1.2-1.6-1.70.5-1.61.50.1-1.00.10.7-1.2-1.2-1.21.2-0.51.0-0.2-0.70.8
Na content in liver0.10.10.80.2-0.20.0-0.1-0.4-0.8-0.9-0.30.40.10.50.10.50.50.6-0.30.10.2-0.1-0.0-0.4-0.40.00.2
Rb content in liver0.20.21.1-0.40.40.30.80.20.40.1-0.3-0.1-0.20.60.7-0.1-0.10.6-0.0-0.3-0.40.3-0.50.51.0-0.70.3
Se content in liver0.30.41.8-0.50.5-0.80.3-0.40.0-1.1-1.30.5-0.50.30.3-0.30.2-0.2-0.8-0.8-1.00.90.6-0.20.30.60.7
Sr content in liver2.11.87.51.4-1.4-0.5-2.2-2.0-1.9-0.8-1.02.1-0.52.7-1.30.31.4-1.21.70.2-0.3-0.30.51.00.6-1.0-1.5
Zn content in liver1.51.75.72.0-2.0-1.7-1.9-2.0-1.9-2.4-1.11.5-0.61.0-1.3-0.30.8-1.20.0-0.2-0.20.10.9-0.4-1.80.6-0.5
Bone: minimum diameter0.20.31.20.3-0.30.8-0.6-0.2-0.50.30.70.30.60.3-0.60.70.5-0.31.10.80.8-0.90.2-0.3-0.0-0.2-0.9
Time in familiar zone, hab. session 11.31.43.5-0.80.80.3-0.6-1.1-1.3-0.80.01.71.20.1-1.51.61.8-1.41.11.20.9-1.11.9-1.3-0.71.4-1.2
Time in novel zone, hab. session 10.40.41.50.5-0.50.5-0.10.80.70.91.2-0.90.4-1.0-0.3-0.6-1.2-0.30.30.50.7-0.5-0.3-0.5-0.90.0-0.5
Total zone transitions, hab. session 10.71.02.3-1.41.41.50.40.2-0.00.41.00.61.4-0.2-0.61.40.7-0.81.41.41.2-1.30.9-1.10.20.6-1.1
Total locomotion distance, hab. session 12.94.110.1-1.21.23.0-0.30.3-0.41.02.80.92.9-0.7-1.92.41.0-1.73.23.12.9-3.11.5-2.2-0.70.6-2.8
Locomotion velocity, hab. session 11.82.66.1-1.21.22.50.00.3-0.20.72.20.72.4-0.5-1.32.21.1-1.12.52.42.3-2.51.2-1.8-0.30.5-2.1
Time in familiar zone, hab. session 20.50.52.1-0.00.00.0-0.7-0.9-0.50.2-0.61.2-0.21.5-0.40.41.0-0.71.10.0-0.4-0.00.41.11.2-0.6-0.7
Time in novel zone, hab. session 20.50.63.10.0-0.00.10.10.4-0.3-0.50.8-0.50.8-1.3-0.30.4-0.30.3-0.60.71.1-0.70.3-1.7-1.71.20.0
Total zone transitions, hab. session 20.40.62.2-1.51.51.31.10.70.50.90.8-0.00.9-0.60.00.70.3-0.31.00.50.4-0.50.3-0.30.70.0-0.4
Total locomotion distance, hab. session 21.31.76.0-1.11.12.00.40.3-0.10.91.80.61.9-0.5-1.11.61.1-1.22.41.81.5-1.80.8-1.00.20.1-1.8
Locomotion velocity, hab. session 21.31.86.1-1.21.22.10.40.2-0.10.91.80.72.0-0.4-1.01.81.2-1.12.51.81.5-1.80.9-1.00.30.1-1.8
Novel to familiar place preference ratio0.70.93.11.1-1.1-1.8-0.2-0.6-0.4-1.4-1.2-0.2-1.20.10.5-0.8-0.10.6-1.7-1.2-1.01.2-0.40.3-0.70.31.2
Novelty place preference0.70.93.40.9-0.9-1.60.1-0.4-0.1-1.3-1.3-0.3-1.20.20.7-0.9-0.40.8-1.8-1.3-1.11.3-0.50.3-0.40.21.4
Time in novel zone, NPP test0.70.83.10.7-0.7-1.60.2-0.4-0.0-1.3-1.3-0.3-1.10.10.7-0.9-0.30.6-1.8-1.3-1.11.3-0.40.3-0.50.41.4
Total zone transitions, NPP test0.81.23.9-0.90.91.31.81.81.52.01.3-1.50.4-1.01.1-0.3-1.00.60.5-0.00.0-0.0-1.20.71.1-1.00.4
Total locomotion distance, NPP test1.92.69.2-1.31.32.61.21.50.81.93.0-0.82.4-1.9-0.61.50.1-0.52.22.12.2-2.10.2-1.3-0.20.1-1.5
Locomotion velocity, NPP test1.72.49.0-1.31.32.51.51.81.12.03.0-1.22.2-2.1-0.31.2-0.2-0.31.81.82.0-1.8-0.1-1.2-0.20.1-1.1
Intraocular pressure0.20.31.4-0.70.70.50.90.71.00.70.3-0.40.1-0.00.60.0-0.2-0.10.5-0.1-0.20.1-0.40.51.2-0.50.2
Delta distance traveled before/after self-admin0.70.82.6-0.50.5-0.3-0.2-0.3-0.3-0.60.50.51.0-1.2-0.91.11.1-1.30.40.80.9-0.81.3-1.3-1.21.6-0.5
Delta ambulatory time before/after self-admin0.50.92.1-0.10.1-0.6-0.7-1.0-0.8-1.10.11.10.8-0.6-1.21.01.3-1.40.50.70.6-0.71.4-1.2-1.21.4-0.8
Parametrial fat weight0.20.62.5-1.11.10.2-0.7-0.9-0.3-0.7-1.21.5-0.01.6-0.20.60.8-0.0-0.1-0.0-0.40.10.9-0.31.00.5-0.2
Pavlov. Cond. lever latency0.60.82.91.4-1.4-1.0-1.7-1.3-1.3-1.3-1.00.9-0.61.1-0.7-0.10.40.1-0.5-0.1-0.10.10.3-0.1-1.00.2-0.2
Pavlov. Cond. magazine entry latency1.01.33.6-0.90.90.91.81.71.91.90.9-1.6-0.1-0.91.3-0.7-1.30.80.0-0.5-0.40.5-1.30.91.3-1.00.7
Pavlov. Cond. change in total contacts1.01.13.6-1.31.31.21.91.61.81.81.3-1.20.6-1.30.6-0.1-0.7-0.30.80.10.0-0.1-0.40.41.2-0.50.1
Pavlov. Cond. index score1.01.34.5-1.51.51.42.11.71.81.91.4-1.30.7-1.30.90.1-0.60.10.80.20.2-0.2-0.60.41.3-0.50.2
Pavlov. Cond. latency score0.91.24.1-1.61.61.32.01.71.71.71.3-1.30.6-1.40.90.0-0.70.10.60.20.2-0.2-0.50.21.0-0.30.3
Pavlov. Cond. lever contacts0.60.72.0-1.21.21.11.41.01.01.41.1-0.50.7-0.80.30.30.0-0.61.20.30.2-0.3-0.00.31.0-0.3-0.3
Pavlov. Cond. magazine entry number1.01.23.70.8-0.8-0.7-1.9-1.6-1.9-1.6-0.61.60.20.8-1.40.81.3-0.70.10.70.6-0.61.2-1.0-1.31.0-0.9
Pavlov. Cond. intertrial magazine entries3.64.48.5-1.21.20.9-1.2-1.0-1.6-0.11.52.02.6-1.0-2.62.92.8-2.62.42.72.4-2.72.9-2.3-1.22.2-2.6
Pavlov. Cond. lever-magazine prob. diff.1.01.34.6-1.41.41.32.21.71.72.01.5-1.30.7-1.30.80.1-0.5-0.01.00.20.1-0.2-0.60.51.3-0.60.1
Pavlov. Cond. response bias1.11.34.9-1.21.21.61.91.81.72.21.6-1.30.7-1.10.70.0-0.70.01.10.30.3-0.3-0.70.51.3-0.9-0.1
Pavlov. Cond. lever latency0.30.51.61.3-1.3-1.0-1.0-0.9-1.0-0.8-0.60.6-0.60.7-0.6-0.40.3-0.60.2-0.2-0.20.10.00.4-0.7-0.3-0.2
Pavlov. Cond. magazine entry latency0.91.23.7-1.31.30.51.91.71.91.10.7-1.60.2-1.71.2-0.6-1.31.0-1.0-0.6-0.30.6-0.6-0.20.40.21.0
Pavlov. Cond. change in total contacts0.30.82.5-1.61.60.41.51.01.40.6-0.1-0.70.1-0.81.1-0.2-0.50.9-0.9-0.6-0.60.7-0.1-0.00.90.40.9
Pavlov. Cond. index score0.71.13.8-1.91.90.81.81.41.70.90.4-1.00.4-1.41.1-0.1-0.70.9-0.9-0.3-0.20.4-0.1-0.50.70.70.9
Pavlov. Cond. latency score0.81.34.3-1.91.90.92.11.71.91.20.7-1.40.5-1.61.2-0.2-0.91.0-0.9-0.3-0.20.4-0.3-0.40.70.51.0
Pavlov. Cond. lever contacts0.20.31.4-1.21.20.60.80.60.80.40.2-0.30.5-0.40.50.4-0.00.5-0.40.00.00.00.2-0.40.60.50.3
Pavlov. Cond. magazine entry number1.31.73.91.3-1.30.3-1.8-1.2-1.9-0.20.81.30.80.6-1.91.21.3-1.72.01.61.5-1.70.9-0.5-1.10.1-1.9
Pavlov. Cond. intertrial magazine entries0.92.05.00.2-0.2-0.2-1.7-1.8-2.1-1.4-0.32.10.90.9-1.71.82.2-1.61.11.31.1-1.31.8-1.2-1.01.3-1.4
Pavlov. Cond. lever-magazine prob. diff.0.71.03.5-1.91.90.71.81.31.60.80.4-1.10.4-1.41.1-0.0-0.70.9-1.0-0.3-0.20.4-0.1-0.60.50.70.9
Pavlov. Cond. response bias0.30.41.5-1.21.20.51.00.71.00.40.1-0.40.3-0.60.70.1-0.30.7-0.6-0.2-0.20.30.0-0.30.60.40.5
Time in closed arm before self-admin0.40.72.50.5-0.5-1.2-0.8-1.2-0.9-0.8-1.11.2-0.50.9-0.6-0.11.0-1.60.6-0.4-0.80.40.80.50.30.4-0.5
Time in closed arm after self-admin0.40.52.71.4-1.4-0.4-1.6-0.8-1.2-0.2-0.10.4-0.30.8-0.6-0.20.2-0.30.40.20.1-0.2-0.10.5-0.1-0.5-0.5
Time in open arm before self-admin2.73.38.4-2.92.92.21.11.00.60.72.00.22.8-1.9-0.42.71.2-0.10.92.42.5-2.31.5-2.6-0.51.8-0.9
Time in open arm after self-admin1.11.22.5-1.41.40.50.80.20.20.31.10.41.6-1.5-0.71.41.0-1.00.81.21.2-1.21.4-1.4-0.91.6-0.8
Bone: periosteal estimation0.40.82.71.0-1.0-0.1-1.6-1.3-1.3-0.6-0.31.4-0.01.5-1.10.41.0-1.01.20.40.2-0.50.70.2-0.1-0.3-1.3
Bone: periosteal perimeter0.20.31.40.4-0.40.90.00.80.40.81.2-0.90.4-0.5-0.0-0.1-0.80.20.50.60.8-0.6-0.5-0.3-0.4-0.3-0.4
Bone: post-yield work1.01.64.8-0.40.42.11.02.01.62.11.4-1.80.1-0.21.1-0.8-2.21.50.30.20.4-0.3-1.80.51.0-1.90.1
Progressive ratio test 1 active lever presses2.54.410.4-3.23.23.23.13.23.22.72.5-2.31.8-2.41.80.7-1.41.50.41.01.2-0.9-0.9-0.71.6-0.60.4
Progressive ratio test 1 breakpoint2.54.210.3-3.13.13.13.13.23.22.72.4-2.31.7-2.31.90.6-1.51.60.30.81.1-0.8-1.0-0.61.6-0.70.5
Progressive ratio test 1 inactive lever presses0.82.26.9-1.61.62.51.82.11.22.02.6-1.61.8-2.20.50.7-0.90.81.11.21.4-1.2-0.5-0.9-0.1-0.3-0.5
Progressive ratio test 2 active lever presses4.05.716.8-4.14.13.73.23.12.92.63.0-1.92.9-3.21.31.8-0.61.20.71.82.1-1.80.1-1.80.80.7-0.1
Progressive ratio test 2 breakpoint4.25.416.2-4.04.03.63.02.92.72.43.0-1.63.0-3.11.11.9-0.41.00.92.02.1-1.90.3-1.90.70.8-0.3
Progressive ratio test 2 inactive lever presses1.13.49.8-3.13.13.12.62.31.91.82.4-1.22.4-2.30.91.6-0.31.10.81.61.7-1.5-0.0-1.50.80.3-0.3
Incentive Sensitization - Responses0.61.66.2-1.61.61.11.31.41.00.91.9-1.01.8-2.50.21.20.10.10.21.31.6-1.20.5-1.6-0.71.4-0.1
Incentive Sensitization - Breakpoint0.71.65.5-1.51.51.01.11.00.70.71.8-0.71.9-2.3-0.11.40.4-0.20.41.41.7-1.40.8-1.7-0.91.6-0.4
Sum of active levers in priming session hrs 5-60.50.52.3-1.11.10.41.50.91.40.50.4-0.70.2-1.10.5-0.2-0.50.0-0.2-0.3-0.20.3-0.1-0.20.50.30.4
Progressive ratio0.10.41.21.1-1.1-0.9-0.1-0.1-0.9-0.6-0.2-0.5-0.6-0.30.3-0.6-0.30.8-0.9-0.4-0.10.4-0.70.3-1.0-0.20.6
Food seeking constrained by brief footshock0.91.13.5-0.60.60.50.1-0.5-1.0-1.00.70.71.3-1.1-1.01.31.10.00.01.11.2-1.01.2-1.9-1.81.5-0.8
Seeking ratio, punishment vs. effort0.40.81.9-1.31.31.20.3-0.10.1-0.00.70.81.4-0.5-0.81.20.8-0.40.80.90.8-0.91.2-1.4-0.30.8-1.0
Retroperitoneal fat weight0.62.57.9-0.90.90.3-1.7-2.1-2.1-1.8-1.02.81.11.5-1.52.42.6-0.20.31.31.0-1.22.3-1.7-0.31.6-1.2
Reaction time number correct0.31.25.60.6-0.6-2.4-1.0-1.5-0.7-1.9-1.71.1-0.90.2-0.5-0.30.9-1.1-1.0-0.9-0.90.91.0-0.0-1.01.50.5
Reaction time mean minus median0.10.92.5-1.31.31.00.80.90.20.81.4-0.41.5-1.6-0.11.10.5-0.20.71.11.1-1.00.5-0.9-0.30.8-0.4
Reaction time mean minus median AUC0.10.92.0-1.01.01.00.00.2-0.20.61.10.41.4-0.8-0.71.30.9-0.91.31.31.1-1.21.0-0.8-0.20.8-1.1
Reaction time num false alarms0.50.93.8-0.80.8-0.4-0.1-0.9-0.7-1.4-0.41.20.8-0.2-0.61.31.4-0.3-0.40.60.6-0.61.5-1.6-1.11.9-0.2
Reaction time num false alarms AUC0.40.93.7-0.20.2-1.2-0.6-1.4-1.0-1.9-1.21.40.10.4-0.60.71.4-0.4-0.7-0.0-0.10.11.4-1.0-1.11.70.0
Reaction time trials correct on left0.31.25.60.6-0.6-2.4-1.0-1.5-0.7-1.9-1.71.1-0.90.2-0.5-0.30.9-1.1-1.0-0.9-0.90.91.0-0.0-1.01.50.5
Reaction time trials on left0.31.15.30.5-0.5-2.3-0.9-1.4-0.6-1.8-1.71.0-0.90.2-0.5-0.30.9-1.1-1.0-0.9-0.90.91.0-0.1-1.01.50.5
Reaction time mean0.40.93.5-1.71.70.61.61.21.00.50.7-0.90.9-1.90.50.4-0.40.5-0.70.30.4-0.20.4-1.1-0.31.20.6
Reaction time mean AUC0.40.93.1-1.71.70.61.61.31.10.60.7-1.00.8-1.70.60.2-0.50.6-0.70.20.4-0.10.3-1.0-0.21.10.7
Median of all reaction times0.40.72.3-1.51.5-0.11.40.80.9-0.00.0-0.60.4-1.50.50.0-0.40.4-1.1-0.2-0.00.30.5-1.0-0.41.30.9
Reaction time omissions0.81.34.4-1.41.40.62.11.82.01.40.5-1.60.1-1.41.4-0.5-1.10.8-0.6-0.5-0.40.5-0.80.30.9-0.11.1
Reaction time false alarm rate0.20.30.8-0.90.90.30.3-0.3-0.2-0.7-0.30.60.60.2-0.10.80.70.3-0.20.30.3-0.30.7-0.9-0.10.8-0.1
Reaction time premature initiation rate1.11.65.51.0-1.0-2.1-0.6-1.4-1.0-1.8-2.30.8-1.81.30.1-1.4-0.2-0.2-1.3-1.7-1.81.70.00.7-0.1-0.01.0
Reaction time premature initiations1.03.010.81.3-1.3-3.3-0.9-1.8-1.1-2.6-3.21.0-2.41.30.2-1.70.1-0.4-2.1-2.3-2.42.30.30.8-0.50.71.6
Std. dev. reaction times0.41.34.3-1.91.91.11.41.40.81.01.4-0.81.6-2.10.31.10.20.30.11.01.1-0.90.6-1.2-0.21.20.1
Reaction time trials completed0.31.15.30.5-0.5-2.3-0.9-1.4-0.6-1.8-1.71.0-0.90.2-0.5-0.30.9-1.1-1.0-0.9-0.90.91.0-0.1-1.01.50.5
Reaction time trials AUC0.31.04.60.3-0.3-2.1-0.7-1.3-0.5-1.7-1.40.9-0.7-0.1-0.5-0.20.9-1.0-1.0-0.7-0.70.71.1-0.2-1.11.60.5
Run reversals in cocaine runway, females1.61.84.8-0.60.60.1-1.2-1.5-1.3-0.7-0.02.21.10.3-1.91.41.9-2.11.51.00.6-1.02.0-1.3-0.61.4-1.8
Run reversals in cocaine runway, males1.21.35.70.5-0.51.90.11.20.61.82.4-1.01.2-0.8-0.50.4-0.7-0.11.71.31.5-1.4-0.6-0.4-0.2-0.8-1.4
Latency to leave start box in cocaine runway0.30.42.70.8-0.8-1.0-1.6-0.6-0.80.4-0.40.4-0.50.3-0.6-0.20.4-0.90.30.0-0.1-0.00.51.0-0.30.2-0.2
Latency to leave start box in cocaine runway, F0.40.52.80.9-0.9-1.7-1.0-0.4-0.70.1-0.7-0.1-0.9-0.3-0.2-0.80.1-0.5-0.6-0.7-0.70.70.21.2-0.70.30.6
Latency to leave start box in cocaine runway, M0.70.62.30.1-0.10.9-1.5-0.3-0.60.70.50.70.60.8-0.80.90.5-0.61.21.21.0-1.20.6-0.20.3-0.1-1.2
Std. dev. time between licks in bursts0.20.31.4-1.21.20.60.80.40.40.70.30.10.6-0.30.20.80.70.10.40.20.1-0.20.4-0.01.10.2-0.0
Total sessions with >9 infusions3.44.212.9-3.53.53.63.12.92.02.52.5-1.82.1-2.31.51.0-1.01.70.71.21.3-1.2-0.8-0.81.4-0.60.1
Short access day 1 total inactive lever presses0.81.75.8-1.91.90.92.32.02.41.70.7-1.70.3-1.41.7-0.2-0.90.5-0.2-0.4-0.30.4-0.80.51.4-0.01.1
Short access day 10 total inactive lever presses0.11.03.90.8-0.8-2.00.1-0.4-0.3-1.1-1.2-0.2-1.2-0.30.3-1.2-0.30.3-1.7-1.5-1.31.5-0.10.5-0.80.51.2
Short access day 1 total infusions2.85.614.3-3.43.43.53.73.83.13.42.8-3.01.8-2.82.40.5-1.72.10.30.81.1-0.8-1.7-0.11.9-0.70.8
Short access day 10 total infusions2.33.79.2-2.22.23.02.83.02.82.51.9-2.50.9-1.52.2-0.1-2.22.5-0.30.30.6-0.3-1.9-0.11.6-1.60.9
Short access total infusions3.75.316.0-3.33.34.03.33.52.93.32.9-2.42.0-2.22.00.9-1.52.00.91.21.4-1.2-1.4-0.31.9-1.20.2
Short access day 1 locomotion2.23.711.9-3.43.43.03.12.72.42.62.1-1.71.8-2.21.40.8-1.01.00.80.90.9-0.8-0.5-0.71.5-0.10.1
Short access day 10 total locomotion0.31.14.3-2.02.02.11.71.10.90.70.5-0.40.70.11.00.7-0.31.50.20.40.4-0.4-0.4-0.51.4-1.00.1
Short access total locomotion2.13.213.6-3.73.73.12.92.01.41.51.8-0.82.1-1.90.91.4-0.21.20.71.11.2-1.10.2-1.50.90.1-0.2
One hour access (0.3 mA shock)2.12.58.1-2.72.72.81.51.41.21.41.8-0.32.2-1.10.32.00.50.51.21.81.7-1.70.7-1.31.00.4-0.8
Compulsive drug intake0.20.41.20.9-0.9-0.5-0.7-0.5-0.60.30.30.30.10.4-0.70.40.9-1.01.10.40.2-0.40.40.60.40.2-0.7
One hour access (shock baseline)1.23.110.4-3.23.22.92.52.32.11.51.7-1.41.8-1.81.41.1-0.91.8-0.31.11.3-1.1-0.2-1.50.60.10.4
Social response proportion2.93.79.1-0.20.2-0.71.41.42.00.3-1.6-2.0-2.10.43.0-2.0-2.52.8-3.0-2.2-1.92.2-2.11.41.6-1.33.0
Social responses1.62.15.9-0.70.70.31.81.82.20.3-0.2-2.1-0.6-0.62.4-0.8-1.92.3-2.3-0.9-0.50.9-1.60.10.8-0.42.3
Social time0.40.64.0-0.80.8-0.40.50.20.1-1.0-0.0-0.20.6-1.40.00.60.2-0.1-1.00.30.6-0.20.9-1.5-1.12.00.5
Soleus weight2.16.115.7-0.40.42.4-2.4-1.1-2.00.42.22.22.80.2-3.32.92.2-2.94.03.43.1-3.52.6-2.3-1.21.0-4.0
Bone: stiffness0.30.61.7-0.70.71.01.21.31.11.31.0-1.10.5-0.80.70.1-0.70.60.40.30.4-0.3-0.70.10.7-0.60.1
Tibialis anterior weight0.62.16.90.0-0.0-0.3-1.8-1.9-1.8-0.4-0.32.40.51.1-2.01.22.4-2.62.30.80.2-0.82.10.20.00.6-2.0
Time to tail flick, vehicle, before self-admin0.10.11.1-0.10.1-0.5-0.0-0.30.2-0.3-0.10.40.1-0.1-0.40.20.4-1.10.30.10.0-0.10.6-0.40.00.6-0.3
Time to tail flick, vehicle, after self-admin0.10.21.10.3-0.3-0.3-0.3-0.0-0.30.10.5-0.10.4-0.9-0.60.10.3-0.70.30.40.5-0.40.4-0.3-1.00.4-0.3
Time to tail flick, test, before self-admin0.10.10.30.2-0.20.60.00.1-0.4-0.10.5-0.10.40.0-0.10.2-0.20.30.40.40.4-0.4-0.1-0.4-0.1-0.1-0.3
Time to tail flick, test, after self-admin1.21.35.52.3-2.3-1.0-1.8-1.4-1.8-1.3-0.90.8-1.01.7-0.7-0.60.1-0.50.2-0.4-0.40.3-0.40.7-0.0-0.9-0.4
Delta time to tail flick, vehicle, before/after SA0.70.82.60.5-0.50.1-0.9-0.4-1.2-0.01.00.31.0-1.0-1.30.70.8-0.80.81.01.1-1.00.8-0.7-1.60.7-1.1
Delta time to tail flick, test, before/after SA0.40.51.51.2-1.2-1.1-1.0-1.1-1.0-1.2-0.60.7-0.40.6-0.70.00.7-0.90.1-0.1-0.10.00.30.0-0.50.1-0.3
Tibia length1.64.517.6-0.30.3-3.8-0.3-2.3-1.3-4.2-3.91.7-1.70.50.2-0.21.6-0.2-3.5-2.2-2.12.31.7-0.8-1.13.02.3
Ambulatory time before self-admin0.82.67.7-2.32.32.32.52.12.32.20.6-1.40.20.12.0-0.3-1.41.80.0-0.3-0.40.3-1.30.82.8-1.60.7
Ambulatory time after self-admin0.71.26.4-2.52.51.41.71.21.51.00.5-0.30.9-0.60.90.80.00.30.30.40.2-0.30.3-0.61.50.20.2
Bone: tissue strength1.81.98.0-1.21.22.81.41.81.62.52.1-1.11.2-0.50.30.4-0.90.51.81.11.0-1.1-0.80.21.4-1.5-0.9
Total heroin consumption0.91.04.4-1.11.1-1.50.90.20.4-1.0-1.1-0.4-0.5-1.40.7-0.4-0.20.2-2.1-1.0-0.71.00.4-0.7-0.81.71.7
Bone: trabecular number0.40.82.61.5-1.5-0.8-0.5-0.4-0.20.2-0.5-0.1-1.11.10.3-1.1-0.3-0.10.2-0.8-0.90.8-1.01.60.5-1.50.1
Bone: trabecular spacing0.10.21.4-0.10.10.20.10.50.20.40.7-0.50.5-1.2-0.30.1-0.2-0.1-0.20.40.6-0.40.2-0.5-0.80.8-0.1
Bone: trabecular thickness0.10.20.6-0.30.3-0.30.70.50.70.50.1-0.6-0.1-0.70.6-0.4-0.30.0-0.3-0.4-0.40.4-0.40.40.30.00.5
Bone: trabecular tissue density0.50.93.1-0.00.01.4-0.00.5-0.41.21.8-0.31.4-0.8-0.51.20.50.21.21.41.5-1.5-0.0-0.4-0.4-0.1-1.0
Water consumed over 24 hours0.10.20.60.4-0.4-0.30.10.20.4-0.4-0.4-0.4-0.60.20.6-0.6-0.60.6-0.8-0.5-0.40.5-0.70.20.1-0.50.6
Number of responses in last shaping day0.20.21.0-0.50.51.00.40.6-0.10.60.8-0.40.5-0.40.20.2-0.30.60.30.50.6-0.5-0.3-0.2-0.0-0.4-0.3