Hub : Genes

Dnmt3a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS XM_017594268.3 0.01 0.01 1.9e-03 0.01 0.01 0.01 0.01 1.5e-02 7.1e-03 2.4e-02 2.9e-02
2 NAcc alternative TSS XM_017594268.3 0.02 0.01 6.8e-04 0.01 0.01 0.01 0.01 8.8e-03 2.5e-03 7.9e-03 1.2e-02
3 Liver alternative polyA XM_017594268.3 0.04 0.04 4.0e-03 0.02 0.01 0.01 0.02 5.6e-03 6.7e-03 1.8e-02 3.5e-03
4 Brain isoform ratio XM_017594268.3 0.02 0.02 6.9e-03 0.01 0.02 0.01 0.01 1.5e-02 1.1e-02 1.8e-02 1.6e-02
5 NAcc isoform ratio XM_017594268.3 0.02 0.02 1.2e-04 0.02 0.02 0.01 0.02 4.0e-04 3.6e-04 2.3e-03 1.0e-03
6 Liver alternative polyA XM_017594268.3 0.03 0.04 4.1e-03 0.02 0.02 0.02 0.02 1.8e-03 4.6e-03 4.8e-03 2.3e-03
7 Adipose alternative polyA XM_017594268.3 0.04 0.03 2.8e-04 0.02 0.03 0.02 0.02 9.8e-04 4.2e-04 1.3e-03 9.4e-04
8 PL alternative TSS XM_017594268.3 0.02 0.02 9.2e-03 0.01 0.01 0 0.01 1.6e-02 7.8e-03 2.7e-01 2.4e-02
9 PL isoform ratio XM_017594268.3 0.03 0.03 1.6e-04 0.03 0.04 0.03 0.02 8.3e-04 1.0e-04 6.1e-04 9.6e-04
10 Brain gene expression Dnmt3a 0.1 0.09 5.3e-06 0.06 0.06 0.06 0.06 1.3e-06 2.6e-06 2.4e-06 1.8e-06
11 Adipose alternative polyA XM_017594268.3 0.04 0.04 2.2e-04 0.02 0.03 0.02 0.02 9.6e-04 3.4e-04 8.7e-04 9.1e-04
12 Liver mRNA stability Dnmt3a 0.02 0.02 9.4e-03 0.02 0.01 0.02 0.01 5.4e-03 9.7e-03 3.7e-03 1.1e-02
13 BLA gene expression Dnmt3a 0.05 0.04 4.4e-03 0.03 0.02 0.01 0.01 1.6e-02 2.7e-02 1.1e-01 6.2e-02
14 OFC isoform ratio XM_017594268.3 0.18 0.15 8.8e-04 0.18 0.14 0.17 0.14 4.9e-05 3.4e-04 5.9e-05 2.6e-04
15 Adipose gene expression Dnmt3a 0.17 0.1 5.6e-17 0.14 0.15 0.15 0.14 5.3e-15 2.5e-16 6.8e-16 1.3e-15
16 Liver intron excision ratio chr6_32512139_32542146 0.41 0.16 6.9e-03 0.01 0.01 0.03 0.01 3.2e-02 2.1e-02 2.1e-04 3.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bone: apparent density2.54.67.4-2.2-2.2-2.4-2.1-2.22.7-2.1-2.1-2.12.3-2.1-2.32.31.9-2.0-0.3
Area under the delay curve0.00.10.3-0.1-0.1-0.0-0.1-0.1-0.3-0.1-0.1-0.10.5-0.10.20.40.1-0.10.6
BMI with tail2.07.08.42.92.92.72.92.8-2.72.82.82.7-2.62.72.1-2.6-2.62.1-2.2
BMI without tail1.36.98.72.82.82.92.82.7-2.92.72.72.7-2.72.62.5-2.6-2.62.3-1.1
Body weight1.98.410.33.23.22.73.23.1-2.73.13.13.0-2.73.02.0-2.8-2.92.4-2.9
Weight adjusted by age0.00.10.20.50.50.40.40.4-0.50.40.40.3-0.30.30.5-0.4-0.1-0.20.0
Bone surface0.40.81.5-0.9-0.9-1.2-0.8-0.81.2-0.8-0.8-0.81.1-0.8-0.91.10.8-0.8-0.4
Bone volume1.22.43.6-1.6-1.6-1.8-1.5-1.51.9-1.5-1.5-1.51.8-1.5-1.71.81.4-1.4-0.2
Breakpoint value in progressive ratio session0.40.70.8-0.9-0.9-0.9-0.9-0.90.8-0.9-0.9-0.90.9-0.9-0.70.60.7-0.80.3
Number of licking bursts0.51.72.01.41.41.31.41.4-1.41.41.31.3-1.31.40.9-1.3-1.31.1-1.0
Context. condit. distance diff. score0.20.20.4-0.5-0.5-0.2-0.5-0.50.7-0.5-0.5-0.50.1-0.5-0.20.20.3-0.5-0.0
Locomotion velocity, session 10.30.40.60.60.60.50.60.7-0.40.70.70.7-0.60.70.3-0.6-0.80.8-0.1
Locomotion distance, session 10.70.92.5-0.9-0.9-1.1-0.8-0.80.8-0.8-0.8-0.81.0-0.8-1.60.90.6-0.61.4
Locomotion velocity, session 20.10.20.60.50.50.50.50.4-0.80.40.40.3-0.30.4-0.0-0.4-0.20.1-0.3
Locomotion distance, session 20.10.22.20.10.1-0.20.10.1-0.20.10.10.10.20.1-0.80.1-0.20.11.5
Locomotion velocity, session 30.00.00.1-0.1-0.10.1-0.1-0.1-0.3-0.0-0.1-0.1-0.1-0.10.1-0.00.0-0.10.1
Locomotion distance, session 30.00.00.10.20.20.20.20.2-0.30.20.20.2-0.30.20.1-0.3-0.30.30.1
Stereotopy head waving bouts, day 32.02.43.1-1.6-1.6-1.6-1.7-1.61.8-1.6-1.6-1.61.5-1.6-1.01.61.6-1.41.0
Stereotopy head waving duration, day 30.30.40.5-0.7-0.7-0.5-0.7-0.70.5-0.7-0.7-0.70.6-0.7-0.10.60.7-0.60.2
Locomotion velocity, session 70.00.00.20.00.10.20.10.0-0.40.10.00.0-0.10.0-0.2-0.1-0.00.00.4
Locomotion distance, session 71.01.32.91.01.01.41.01.0-1.71.01.01.0-1.31.01.3-1.3-0.91.00.7
Stereotopy head waving bouts, day 70.00.00.1-0.00.00.00.00.00.20.10.00.1-0.10.10.2-0.0-0.10.1-0.2
Stereotopy head waving duration, day 70.30.40.5-0.6-0.6-0.6-0.6-0.70.7-0.6-0.6-0.60.6-0.6-0.40.70.6-0.6-0.1
Locomotion velocity, session 80.50.61.4-0.7-0.7-0.8-0.7-0.71.2-0.7-0.7-0.70.6-0.7-1.00.50.7-0.8-0.8
Locomotion distance, session 80.50.74.5-0.9-0.9-0.5-0.8-0.80.5-0.8-0.8-0.70.5-0.8-0.60.50.5-0.42.1
Degree of sensitization distance0.90.91.71.01.01.11.01.0-1.30.91.00.9-1.00.91.2-1.0-0.80.80.1
Degree of sensitization stereotypy0.30.30.40.60.60.50.60.6-0.40.60.60.6-0.50.60.6-0.5-0.70.6-0.2
Conditioned locomotion2.63.13.8-1.8-1.8-1.7-1.8-1.81.4-1.8-1.8-1.81.8-1.9-1.21.92.0-1.81.5
Cocaine response after cond. corrected0.10.10.2-0.4-0.4-0.2-0.4-0.40.3-0.4-0.4-0.40.3-0.4-0.40.30.4-0.4-0.0
Cocaine response after cond. not corrected0.50.70.8-0.8-0.8-0.8-0.8-0.80.8-0.8-0.8-0.80.8-0.8-0.80.90.8-0.80.5
Cocaine response before conditioning2.22.73.9-1.6-1.6-1.9-1.6-1.61.5-1.6-1.6-1.62.0-1.6-1.41.91.6-1.61.4
Saline control response1.31.82.9-1.3-1.3-1.6-1.3-1.31.7-1.3-1.3-1.31.5-1.3-1.11.61.4-1.20.3
Bone: connectivity density1.52.54.7-1.6-1.6-1.8-1.6-1.62.2-1.5-1.6-1.61.7-1.5-1.41.71.5-1.6-0.3
Bone: cortical apparent density0.10.10.5-0.2-0.2-0.5-0.3-0.20.7-0.2-0.2-0.20.5-0.2-0.10.50.1-0.2-0.1
Bone: cortical area0.00.00.10.10.10.00.10.1-0.40.10.10.1-0.00.1-0.2-0.0-0.20.2-0.0
Bone: cortical porosity3.33.64.4-1.9-1.9-2.0-1.9-1.92.1-1.9-1.9-2.02.0-1.9-1.92.02.0-2.1-0.4
Bone: cortical porosity3.03.34.1-1.8-1.8-1.9-1.8-1.82.0-1.8-1.8-1.91.9-1.8-2.01.91.9-2.0-0.5
Bone: cortical thickness0.20.30.70.60.60.50.60.6-0.80.60.60.6-0.50.60.4-0.5-0.70.7-0.1
Bone: cortical thickness0.40.51.5-0.7-0.7-0.8-0.7-0.60.6-0.7-0.6-0.70.8-0.7-1.20.80.4-0.60.6
Bone: cortical tissue density0.10.10.4-0.2-0.2-0.5-0.2-0.10.7-0.2-0.1-0.10.5-0.1-0.10.40.0-0.1-0.3
Condit. Reinf. active minus inactive responses2.32.63.11.71.71.61.71.7-1.51.71.71.7-1.61.71.1-1.6-1.71.5-1.3
Condit. Reinf. active-inactive response ratio2.52.74.21.71.71.61.61.6-1.41.61.61.6-1.71.61.4-1.7-1.71.4-2.1
Condit. Reinf. active responses0.10.20.30.50.50.30.50.5-0.40.50.50.5-0.40.5-0.1-0.4-0.60.4-0.1
Condit. Reinf. inactive responses1.51.93.4-1.3-1.3-1.5-1.3-1.21.2-1.3-1.2-1.31.5-1.3-1.71.51.3-1.21.8
Incentive salience index mean0.30.41.50.70.70.50.70.7-0.40.70.60.6-0.60.6-0.1-0.5-0.70.3-1.2
Condit. Reinf. lever presses0.91.43.4-1.1-1.1-1.2-1.1-1.11.2-1.1-1.1-1.21.2-1.1-1.81.31.2-1.3-0.1
Condit. Reinf. active minus inactive responses0.81.21.5-1.1-1.1-1.2-1.1-1.11.0-1.1-1.1-1.11.2-1.1-0.91.21.1-1.10.6
Condit. Reinf. active-inactive response ratio0.30.50.8-0.7-0.7-0.7-0.7-0.70.7-0.7-0.8-0.80.7-0.8-0.80.80.8-0.9-0.1
Condit. Reinf. active responses0.60.81.3-0.8-0.8-1.1-0.9-0.80.9-0.9-0.8-0.91.2-0.9-0.81.10.8-0.80.8
Condit. Reinf. inactive responses0.20.31.3-0.4-0.4-0.6-0.4-0.30.3-0.4-0.3-0.40.7-0.4-0.60.60.3-0.31.2
Condit. Reinf. lever presses0.91.31.4-1.1-1.2-1.1-1.2-1.10.9-1.2-1.1-1.11.2-1.2-1.11.11.0-1.11.2
Condit. Reinf. lever reinforcers received0.60.81.3-0.8-0.8-1.1-0.8-0.80.9-0.9-0.8-0.81.1-0.9-0.91.10.8-0.90.7
Conditioned reinforcement - actives1.45.67.6-2.4-2.4-2.6-2.5-2.42.4-2.4-2.4-2.42.4-2.4-2.82.32.3-2.21.0
Conditioned reinforcement - inactives2.77.58.6-2.9-2.9-2.9-2.9-2.92.9-2.8-2.8-2.82.8-2.7-2.92.72.7-2.41.1
Conditioned locomotion2.23.35.4-1.8-1.8-2.2-1.8-1.82.3-1.7-1.7-1.82.0-1.7-2.11.91.7-1.7-0.2
Patch foraging indifference point 0 sec0.20.61.00.70.70.90.70.7-1.00.80.80.8-0.80.80.4-0.9-0.81.00.1
Patch foraging indifference point AUC0.00.10.7-0.0-0.00.40.0-0.0-0.5-0.0-0.00.0-0.4-0.00.4-0.30.00.10.8
Delay disc. indifference point, 0s delay0.40.51.20.60.60.60.70.7-0.90.70.70.7-0.20.71.1-0.2-0.50.9-0.0
Delay disc. indifference point, 16s delay0.00.00.10.10.10.10.10.1-0.10.10.10.10.10.10.20.1-0.10.10.4
Delay disc. indifference point, 2s delay0.10.10.40.20.20.20.20.2-0.10.30.20.2-0.20.30.6-0.2-0.30.3-0.6
Delay disc. indifference point, 24s delay1.82.93.6-1.8-1.7-1.9-1.7-1.71.9-1.7-1.7-1.71.9-1.7-1.91.51.6-1.60.8
Delay disc. indifference point, 4s delay0.20.21.10.30.30.30.30.3-0.70.20.30.30.10.20.7-0.1-0.30.31.1
Delay disc. indifference point, 8s delay0.00.10.4-0.1-0.10.0-0.1-0.2-0.4-0.1-0.2-0.10.6-0.20.30.40.3-0.10.6
Indifference point function ln k0.82.53.1-1.7-1.7-1.7-1.6-1.61.8-1.6-1.6-1.61.7-1.6-1.51.71.5-1.50.5
Indifference point function log k0.82.53.1-1.7-1.7-1.7-1.6-1.61.8-1.6-1.6-1.61.7-1.6-1.51.71.5-1.50.5
Patch foraging total patch changes 0 sec0.20.61.10.70.70.90.70.7-1.00.70.80.8-0.80.80.4-0.9-0.71.00.4
Patch foraging total patch changes 12 sec1.11.52.61.31.31.41.21.2-1.61.21.21.2-1.31.11.1-1.4-1.11.0-0.5
Patch foraging total patch changes 18 sec0.40.91.11.01.00.91.01.0-1.01.01.01.0-0.91.00.9-1.0-1.01.0-0.1
Patch foraging total patch changes 24 sec0.51.73.61.31.31.51.31.3-1.91.31.31.3-1.41.31.1-1.4-1.21.30.2
Patch foraging total patch changes 6 sec1.62.64.81.51.61.91.61.5-2.21.61.61.6-1.71.61.5-1.8-1.51.7-0.1
Patch foraging time to switch 0 sec0.20.91.81.01.00.80.90.9-0.70.90.90.9-0.80.91.3-0.9-0.90.7-1.2
Patch foraging water rate 0 sec0.82.93.8-1.8-1.8-1.8-1.7-1.71.6-1.7-1.6-1.61.8-1.6-1.91.81.5-1.22.0
Patch foraging water rate 12 sec0.00.10.10.20.20.30.20.2-0.10.20.20.2-0.20.30.0-0.1-0.30.3-0.3
Patch foraging water rate 18 sec0.92.03.0-1.6-1.5-1.5-1.5-1.41.5-1.4-1.4-1.31.5-1.3-1.61.61.1-0.81.7
Patch foraging water rate 24 sec0.10.10.20.40.40.20.40.4-0.20.40.40.3-0.20.3-0.0-0.1-0.30.2-0.5
Patch foraging water rate 6 sec0.40.61.9-0.8-0.8-0.8-0.8-0.70.6-0.7-0.7-0.70.7-0.7-0.80.80.5-0.31.4
Seeking ratio, delayed vs. immediate footshock0.20.21.50.40.40.60.40.4-0.40.40.30.3-0.30.30.4-0.2-0.10.0-1.2
Distance traveled before self-admin0.00.10.5-0.2-0.2-0.2-0.3-0.20.1-0.3-0.2-0.30.4-0.3-0.60.20.3-0.20.7
Distance traveled after self-admin0.50.81.20.80.81.00.80.9-0.90.90.90.9-1.10.91.0-1.0-0.91.1-0.3
Extensor digitorum longus weight2.39.111.0-3.1-3.1-3.3-3.0-3.13.2-3.0-3.1-3.13.2-3.0-3.33.23.0-2.90.8
Bone: elastic displacement1.41.73.9-1.4-1.4-1.4-1.4-1.42.0-1.3-1.3-1.31.2-1.3-1.21.21.1-1.2-0.1
Bone: elastic work0.50.72.1-0.9-0.9-0.8-0.9-0.91.5-0.8-0.9-0.80.6-0.7-0.70.60.5-0.6-0.7
Bone: endosteal estimation0.10.30.5-0.6-0.6-0.5-0.5-0.50.6-0.5-0.6-0.50.3-0.5-0.70.30.5-0.40.3
Bone: endosteal perimeter0.00.10.3-0.1-0.1-0.2-0.1-0.10.4-0.1-0.1-0.10.1-0.1-0.40.10.1-0.2-0.6
Epididymis fat weight11.356.965.38.18.17.58.07.9-7.17.97.97.7-7.57.76.7-7.6-7.46.7-6.7
Delta time in closed arm before/after self-admin0.10.10.30.20.20.60.10.1-0.50.10.10.2-0.30.10.5-0.2-0.20.20.4
Delta time in open arm before/after self-admin0.00.00.20.20.2-0.00.20.20.00.20.10.10.00.1-0.5-0.2-0.1-0.1-0.5
Diff in mean of infusions in LGA sessions0.20.31.80.50.50.60.50.4-0.10.50.40.3-0.60.40.3-0.6-0.40.1-1.3
Delay discount exponential model param0.10.20.50.30.30.30.30.3-0.00.30.40.4-0.70.40.0-0.5-0.40.3-0.6
Extinction: sum of active levers before priming0.20.40.8-0.5-0.5-0.3-0.6-0.60.2-0.6-0.6-0.70.8-0.7-0.60.60.8-0.9-0.4
Active lever presses in extinction session 62.12.13.6-1.4-1.4-1.5-1.4-1.41.6-1.4-1.4-1.51.6-1.4-1.91.41.4-1.7-0.9
Bone: final force0.10.22.30.20.20.00.20.1-0.00.20.10.2-0.10.2-0.1-0.1-0.20.0-1.5
Bone: final moment0.10.12.10.10.1-0.00.20.10.00.20.10.1-0.00.2-0.0-0.0-0.20.0-1.4
Food consumed during 24 hour testing period0.10.22.00.00.00.30.10.1-0.60.10.10.1-0.30.1-0.2-0.3-0.20.41.4
Glucose0.91.42.01.21.21.31.21.2-1.11.21.21.2-1.21.21.4-1.3-1.21.1-1.0
Heart weight1.21.93.71.41.41.51.41.4-1.51.41.41.4-1.31.31.9-1.5-1.41.4-0.4
Delay discount hyperbolic model param0.00.00.30.10.10.00.10.10.20.10.10.1-0.40.1-0.3-0.3-0.10.0-0.5
Intermittent access intake day 1-15 change0.21.42.3-1.3-1.3-1.4-1.3-1.21.5-1.2-1.1-1.10.9-1.1-1.11.00.8-0.51.5
Intermittent access intake escalation0.10.72.4-1.0-1.0-1.0-0.9-0.81.1-0.9-0.8-0.70.5-0.7-0.60.60.5-0.11.6
Intermittent access intake escalation 20.10.22.0-0.5-0.5-0.5-0.4-0.30.6-0.4-0.3-0.20.2-0.3-0.00.20.00.41.4
Intermitt. access day 1 inactive lever presses0.11.51.9-1.3-1.2-1.0-1.2-1.30.9-1.2-1.3-1.31.3-1.3-1.31.31.4-1.30.3
Intermitt. access day 15 inactive lever presses0.31.41.9-1.2-1.2-1.0-1.2-1.31.0-1.2-1.3-1.31.1-1.2-0.91.11.4-1.4-0.4
Intermitt. access escalation Index1.85.710.72.42.42.52.42.4-2.62.42.42.4-2.22.43.3-2.2-2.42.4-0.4
Intermittent access day 1 total infusions0.82.43.2-1.6-1.6-1.3-1.6-1.71.1-1.6-1.7-1.71.4-1.7-1.41.51.8-1.80.7
Intermittent access day 15 total infusions1.22.93.4-1.8-1.9-1.7-1.8-1.81.7-1.8-1.8-1.81.5-1.8-1.51.51.7-1.51.5
Intermittent access terminal intake (last 3 days)2.23.94.7-2.2-2.2-1.9-2.1-2.11.9-2.1-2.1-2.11.7-2.1-1.91.91.9-1.71.6
Intermittent access total infusions3.64.34.9-2.2-2.2-2.1-2.2-2.22.0-2.2-2.2-2.22.0-2.2-2.22.02.1-2.10.7
Intermittent access day 1 locomotion1.63.03.4-1.8-1.8-1.6-1.8-1.81.6-1.8-1.8-1.81.7-1.8-1.81.71.8-1.71.2
Intermittent access day 15 total locomotion0.00.10.3-0.5-0.4-0.3-0.4-0.40.4-0.4-0.4-0.30.2-0.3-0.60.10.2-0.00.4
Intermittent access total locomotion1.61.93.4-1.5-1.4-1.5-1.4-1.41.5-1.4-1.4-1.41.3-1.4-1.81.21.2-1.11.0
Intermittent access standard deviation0.42.23.1-1.6-1.6-1.6-1.6-1.51.5-1.5-1.5-1.51.2-1.5-1.81.31.4-1.21.1
Left kidney weight0.10.71.7-0.6-0.6-0.7-0.7-0.80.8-0.7-0.8-0.90.8-0.8-1.20.71.0-1.3-0.3
Right kidney weight0.10.53.70.70.70.60.70.6-0.30.70.60.5-0.40.5-0.1-0.6-0.3-0.1-1.9
Cocaine induced anxiety0.00.10.3-0.3-0.4-0.6-0.4-0.30.5-0.3-0.3-0.30.2-0.3-0.10.30.2-0.20.0
Post-drug Anxiety1.31.52.31.21.21.11.31.2-1.41.21.31.3-1.51.31.1-1.4-1.31.3-0.1
Baseline Anxiety2.23.74.92.02.02.12.02.0-2.22.02.02.0-2.02.01.6-2.0-2.01.9-0.3
Tail length0.00.10.6-0.3-0.3-0.3-0.3-0.30.5-0.3-0.2-0.20.3-0.2-0.20.20.10.10.7
Length with tail0.10.21.70.40.4-0.20.40.40.20.40.40.40.10.4-0.7-0.2-0.40.2-1.3
Length without tail0.10.53.1-0.1-0.1-0.7-0.1-0.10.6-0.1-0.1-0.20.5-0.2-1.70.40.2-0.7-1.8
Times rat made contact with spout0.91.02.6-1.0-1.0-1.1-0.9-0.91.3-0.9-0.9-1.01.0-0.9-1.61.00.9-0.90.1
Lifetime Intake3.84.75.4-2.3-2.3-2.2-2.3-2.32.1-2.3-2.3-2.32.1-2.3-2.32.12.3-2.20.6
Liver weight, left1.83.24.61.81.81.81.81.8-1.21.81.81.8-1.91.81.6-2.0-1.81.7-2.1
Liver weight, right2.95.17.52.42.42.22.42.3-2.02.42.32.3-2.12.31.8-2.3-2.12.0-2.7
Locomotor activity0.81.25.11.21.21.01.21.1-0.91.11.11.0-0.91.10.2-0.9-0.90.6-2.3
Locomotor testing distance0.30.83.11.01.00.81.00.9-0.70.90.90.8-0.80.90.3-0.6-0.60.4-1.7
Locomotor testing rearing0.10.51.6-0.4-0.4-0.6-0.5-0.50.4-0.5-0.6-0.60.8-0.6-1.00.90.8-1.0-1.3
Locomotion in novel chamber0.30.44.70.50.50.20.50.4-0.20.40.30.3-0.10.3-0.70.0-0.2-0.2-2.2
Locomotion in novel chamber post-restriction0.92.84.51.71.71.31.71.8-1.51.71.81.8-1.31.82.1-1.5-1.81.9-0.4
Fecal boli incidents, locomotor time 11.23.13.7-1.9-1.9-1.7-1.9-1.91.5-1.9-1.9-1.91.7-1.9-1.61.61.8-1.61.5
Change in fecal boli incidents, locomotor task3.53.85.52.02.02.01.92.0-2.01.92.02.0-2.01.92.3-1.8-1.81.8-1.2
Time >=10cm from walls, locomotor time 10.40.50.9-0.7-0.7-0.9-0.7-0.70.7-0.7-0.7-0.70.8-0.8-0.70.70.7-0.80.6
Bouts of movement, locomotor time 10.30.45.7-0.2-0.20.3-0.1-0.1-0.9-0.2-0.1-0.00.3-0.1-0.2-0.10.10.42.4
Total resting periods, locomotor time 10.40.56.7-0.3-0.20.2-0.2-0.2-0.9-0.2-0.1-0.10.3-0.2-0.2-0.10.10.42.6
Rest time, locomotor task time 10.30.52.10.30.30.90.40.4-1.50.40.40.5-0.30.40.8-0.7-0.50.81.3
Distance moved, locomotor task time 10.20.55.30.40.4-0.20.40.40.90.40.40.3-0.70.4-0.2-0.2-0.2-0.1-2.3
Vertical activity count, locomotor time 10.00.32.40.20.2-0.50.20.21.20.20.20.1-0.20.2-0.20.0-0.1-0.0-1.5
Time >=10cm from walls, locomotor time 20.61.72.5-1.4-1.4-1.3-1.4-1.41.6-1.4-1.4-1.41.1-1.4-0.91.21.5-1.5-0.2
Bouts of movement, locomotor time 20.20.74.00.40.40.60.50.5-1.40.50.60.6-0.40.50.7-0.7-0.71.02.0
Total resting periods, locomotor time 20.20.73.30.50.50.70.50.6-1.50.50.60.6-0.40.50.8-0.8-0.71.01.8
Rest time, locomotor task time 20.00.00.2-0.1-0.10.1-0.0-0.0-0.5-0.0-0.0-0.00.5-0.0-0.10.1-0.00.10.3
Distance moved, locomotor task time 20.20.33.9-0.0-0.0-0.2-0.0-0.11.00.0-0.0-0.0-0.50.00.0-0.10.1-0.2-2.0
Vertical activity count, locomotor time 20.20.43.4-0.3-0.3-0.4-0.4-0.41.1-0.3-0.4-0.30.0-0.30.30.20.5-0.5-1.8
Light reinforcement 10.21.01.7-1.0-1.0-1.0-1.0-1.00.8-1.0-1.0-0.91.1-1.0-0.61.10.9-0.81.3
Light reinforcement 20.81.93.6-1.4-1.4-1.4-1.4-1.31.4-1.4-1.3-1.31.5-1.3-0.41.41.4-1.01.9
Bone: marrow area0.10.30.6-0.6-0.6-0.5-0.5-0.50.6-0.5-0.5-0.50.3-0.5-0.70.40.5-0.40.3
Bone: maximum diameter0.00.00.1-0.2-0.2-0.2-0.1-0.10.1-0.1-0.1-0.10.1-0.1-0.30.10.00.00.3
Bone: maximum force0.00.10.4-0.1-0.1-0.2-0.1-0.1-0.0-0.1-0.1-0.10.2-0.1-0.40.20.1-0.2-0.7
Bone: maximum moment0.00.10.4-0.2-0.2-0.3-0.2-0.20.0-0.1-0.2-0.20.3-0.1-0.30.30.1-0.2-0.6
Mean time between licks in bursts0.31.82.41.31.31.41.41.4-1.41.41.31.4-1.41.41.5-1.5-1.51.5-0.4
Mean num. licks in bursts0.92.33.5-1.6-1.6-1.6-1.6-1.61.9-1.6-1.6-1.51.5-1.5-1.41.51.4-1.30.8
Cd content in liver0.10.10.20.50.40.30.40.4-0.50.40.40.4-0.40.30.1-0.4-0.40.20.3
Co content in liver4.75.56.8-2.3-2.3-2.6-2.3-2.32.3-2.4-2.3-2.42.5-2.4-2.62.32.3-2.61.4
Cu content in liver0.20.30.8-0.3-0.3-0.5-0.4-0.4-0.0-0.5-0.4-0.50.6-0.6-0.50.60.6-0.90.6
Fe content in liver2.12.64.4-1.6-1.6-1.8-1.6-1.61.8-1.6-1.6-1.61.6-1.6-2.11.61.5-1.60.6
K content in liver0.40.31.40.60.60.60.60.6-1.20.50.50.5-0.50.50.5-0.6-0.50.3-0.4
Mg content in liver0.10.10.60.10.00.10.00.0-0.7-0.00.00.00.0-0.10.50.00.0-0.10.8
Mn content in liver0.60.71.20.80.80.80.80.8-1.10.80.80.8-0.80.81.0-0.8-0.70.8-0.6
Na content in liver2.12.43.1-1.8-1.7-1.6-1.7-1.71.7-1.7-1.7-1.61.4-1.6-1.21.51.6-1.40.2
Rb content in liver0.10.10.30.40.40.40.40.4-0.50.40.40.4-0.40.30.4-0.4-0.30.2-0.0
Se content in liver0.10.10.30.40.40.10.30.4-0.30.30.40.3-0.10.3-0.0-0.2-0.20.1-0.6
Sr content in liver0.10.10.2-0.3-0.3-0.2-0.3-0.30.3-0.3-0.3-0.30.2-0.3-0.40.20.2-0.10.2
Zn content in liver0.70.81.81.01.00.90.91.0-1.30.90.90.8-0.90.71.0-1.0-0.90.50.5
Bone: minimum diameter0.61.11.81.11.11.21.11.1-1.41.11.01.0-1.11.00.5-1.1-0.90.8-0.7
Time in familiar zone, hab. session 10.91.01.81.11.11.21.01.0-1.41.01.00.9-1.10.90.9-1.1-0.70.7-0.8
Time in novel zone, hab. session 10.30.31.10.60.60.30.60.5-0.10.60.60.5-0.40.60.3-0.4-0.70.4-1.0
Total zone transitions, hab. session 10.30.41.3-0.7-0.7-0.6-0.6-0.60.6-0.6-0.6-0.60.5-0.5-1.10.50.3-0.30.9
Total locomotion distance, hab. session 11.01.42.6-1.2-1.2-1.3-1.2-1.11.2-1.1-1.1-1.11.2-1.1-1.61.10.9-0.81.4
Locomotion velocity, hab. session 11.82.54.3-1.7-1.7-1.6-1.6-1.61.5-1.6-1.5-1.51.5-1.5-1.81.51.3-1.12.1
Time in familiar zone, hab. session 20.40.40.80.60.60.90.60.6-0.80.60.60.6-0.80.60.8-0.8-0.50.7-0.3
Time in novel zone, hab. session 20.10.10.50.30.3-0.30.20.20.20.20.20.10.20.1-0.10.1-0.2-0.2-0.7
Total zone transitions, hab. session 20.10.10.40.10.10.10.20.20.20.20.20.2-0.20.3-0.6-0.3-0.40.60.2
Total locomotion distance, hab. session 20.10.10.30.20.20.10.30.30.20.30.30.3-0.20.4-0.5-0.3-0.50.60.0
Locomotion velocity, hab. session 20.10.10.50.00.0-0.10.10.10.40.10.20.2-0.00.2-0.7-0.1-0.40.40.2
Novel to familiar place preference ratio0.10.20.50.30.40.30.40.4-0.50.40.50.5-0.20.5-0.0-0.3-0.50.70.5
Novelty place preference0.30.40.80.60.60.50.70.7-0.80.70.70.7-0.30.70.1-0.4-0.80.90.3
Time in novel zone, NPP test0.30.40.60.60.60.50.70.7-0.80.70.70.7-0.30.70.0-0.4-0.70.80.2
Total zone transitions, NPP test1.01.43.3-1.2-1.2-1.2-1.1-1.11.0-1.1-1.1-1.21.2-1.1-1.81.11.1-1.11.1
Total locomotion distance, NPP test1.52.24.0-1.5-1.5-1.6-1.4-1.41.3-1.4-1.4-1.41.5-1.4-2.01.51.3-1.31.5
Locomotion velocity, NPP test2.02.94.7-1.8-1.8-1.9-1.7-1.71.8-1.7-1.7-1.71.8-1.6-2.21.71.5-1.41.2
Intraocular pressure3.04.96.02.42.42.12.42.4-2.02.32.42.4-2.02.32.4-1.9-2.22.2-0.9
Delta distance traveled before/after self-admin2.12.34.01.41.41.61.41.4-1.31.41.41.5-2.01.51.6-1.7-1.51.6-1.2
Delta ambulatory time before/after self-admin0.30.51.30.50.50.70.50.5-0.50.60.60.6-1.10.71.1-0.7-0.70.9-0.7
Parametrial fat weight22.452.761.97.57.57.97.47.3-7.17.47.37.2-7.77.37.1-7.5-6.96.4-6.5
Pavlov. Cond. lever latency0.50.71.20.80.80.90.80.8-1.00.80.80.8-0.80.81.1-0.8-0.90.90.2
Pavlov. Cond. magazine entry latency0.00.00.3-0.0-0.0-0.20.00.00.20.00.0-0.00.1-0.0-0.50.20.0-0.1-0.2
Pavlov. Cond. change in total contacts0.10.10.1-0.3-0.3-0.1-0.2-0.30.1-0.3-0.3-0.30.1-0.3-0.40.10.3-0.30.3
Pavlov. Cond. index score0.10.20.5-0.3-0.3-0.5-0.3-0.30.5-0.3-0.3-0.40.4-0.3-0.70.50.4-0.5-0.2
Pavlov. Cond. latency score0.10.10.4-0.3-0.2-0.4-0.2-0.20.6-0.2-0.2-0.30.3-0.2-0.60.40.3-0.3-0.4
Pavlov. Cond. lever contacts0.60.71.1-0.8-0.8-0.9-0.8-0.81.0-0.8-0.8-0.80.8-0.8-1.10.90.9-0.9-0.2
Pavlov. Cond. magazine entry number0.10.20.90.40.30.50.30.3-0.40.30.30.3-0.40.30.9-0.5-0.30.2-0.4
Pavlov. Cond. intertrial magazine entries1.51.82.7-1.3-1.3-1.5-1.4-1.31.4-1.4-1.4-1.41.4-1.4-0.91.31.4-1.60.2
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-0.7-0.7-0.8-0.7-0.70.8-0.7-0.7-0.70.7-0.7-1.00.80.8-0.80.1
Pavlov. Cond. response bias0.91.11.9-1.0-1.0-1.1-1.0-1.01.0-1.0-1.0-1.01.0-1.0-1.41.11.1-1.10.5
Pavlov. Cond. lever latency0.50.73.00.80.80.60.80.8-0.20.80.80.8-0.70.80.6-0.7-0.70.6-1.7
Pavlov. Cond. magazine entry latency0.00.00.10.20.20.10.10.2-0.20.20.20.2-0.10.20.3-0.2-0.20.20.3
Pavlov. Cond. change in total contacts0.00.00.0-0.2-0.20.0-0.2-0.20.0-0.2-0.2-0.2-0.0-0.2-0.1-0.00.1-0.10.1
Pavlov. Cond. index score0.20.30.5-0.6-0.6-0.4-0.6-0.60.3-0.6-0.6-0.60.5-0.6-0.40.40.5-0.50.7
Pavlov. Cond. latency score0.20.30.7-0.6-0.6-0.4-0.6-0.60.3-0.6-0.6-0.60.5-0.6-0.30.40.5-0.50.9
Pavlov. Cond. lever contacts0.30.42.2-0.6-0.6-0.4-0.6-0.60.0-0.6-0.6-0.60.5-0.6-0.40.40.5-0.51.5
Pavlov. Cond. magazine entry number0.10.10.2-0.4-0.4-0.4-0.4-0.40.5-0.4-0.4-0.40.4-0.4-0.40.50.4-0.20.3
Pavlov. Cond. intertrial magazine entries1.22.63.41.71.71.51.71.7-0.81.71.71.7-1.71.80.9-1.8-1.91.8-1.5
Pavlov. Cond. lever-magazine prob. diff.0.00.10.2-0.3-0.3-0.1-0.3-0.30.1-0.3-0.3-0.30.2-0.2-0.20.10.1-0.20.4
Pavlov. Cond. response bias0.40.61.9-0.8-0.8-0.6-0.8-0.80.3-0.8-0.8-0.80.7-0.8-0.60.60.7-0.71.4
Time in closed arm before self-admin0.10.10.50.40.4-0.10.40.40.40.40.40.4-0.10.4-0.7-0.3-0.20.3-0.6
Time in closed arm after self-admin0.70.72.30.90.90.70.90.9-0.20.90.90.9-0.80.9-0.2-0.7-0.70.6-1.5
Time in open arm before self-admin0.00.10.40.00.00.3-0.0-0.0-0.5-0.0-0.0-0.0-0.2-0.00.6-0.0-0.20.00.0
Time in open arm after self-admin0.10.10.5-0.3-0.3-0.3-0.3-0.3-0.1-0.3-0.3-0.30.2-0.30.10.10.1-0.20.7
Bone: periosteal estimation0.10.30.7-0.6-0.6-0.5-0.5-0.50.3-0.5-0.6-0.50.4-0.5-0.90.40.5-0.40.7
Bone: periosteal perimeter0.00.00.1-0.1-0.1-0.2-0.1-0.10.1-0.1-0.1-0.10.1-0.1-0.30.10.1-0.10.0
Bone: post-yield work1.32.32.9-1.5-1.5-1.6-1.6-1.61.2-1.5-1.6-1.61.5-1.6-1.71.51.6-1.60.5
Progressive ratio test 1 active lever presses1.42.53.1-1.7-1.7-1.5-1.7-1.71.4-1.7-1.8-1.71.4-1.7-1.61.51.7-1.70.5
Progressive ratio test 1 breakpoint1.52.63.2-1.7-1.7-1.4-1.7-1.81.4-1.7-1.8-1.81.4-1.7-1.61.41.7-1.70.5
Progressive ratio test 1 inactive lever presses1.95.06.3-2.3-2.3-2.0-2.3-2.41.9-2.3-2.4-2.42.2-2.4-2.32.02.5-2.50.7
Progressive ratio test 2 active lever presses2.63.64.5-2.0-2.0-2.0-2.0-2.02.1-2.0-2.0-1.91.9-1.9-2.11.71.8-1.70.9
Progressive ratio test 2 breakpoint2.63.34.0-2.0-2.0-1.9-1.9-1.92.0-1.9-1.9-1.91.8-1.9-1.91.61.7-1.61.0
Progressive ratio test 2 inactive lever presses1.34.35.2-2.3-2.3-2.2-2.2-2.22.2-2.2-2.2-2.21.9-2.1-2.11.82.0-1.80.7
Incentive Sensitization - Responses1.12.93.6-1.8-1.8-1.8-1.8-1.81.9-1.8-1.8-1.81.7-1.8-1.71.61.6-1.60.9
Incentive Sensitization - Breakpoint1.02.32.8-1.6-1.6-1.6-1.6-1.61.7-1.6-1.6-1.61.5-1.6-1.51.41.5-1.40.9
Sum of active levers in priming session hrs 5-60.10.10.40.30.30.30.30.3-0.40.30.30.3-0.10.30.3-0.4-0.30.40.6
Progressive ratio0.00.11.60.20.2-0.10.20.20.30.20.10.10.20.1-0.5-0.1-0.2-0.1-1.3
Food seeking constrained by brief footshock12.816.019.7-4.0-4.0-4.1-4.1-4.14.1-4.1-4.2-4.23.7-4.2-4.23.94.1-4.41.6
Seeking ratio, punishment vs. effort0.92.13.7-1.5-1.5-1.3-1.6-1.51.2-1.6-1.5-1.51.1-1.5-1.01.31.5-1.31.9
Retroperitoneal fat weight34.6154.7174.013.213.212.913.012.9-12.112.912.812.7-12.612.612.1-12.4-12.111.0-10.4
Reaction time number correct0.10.51.5-0.7-0.7-0.8-0.6-0.61.2-0.6-0.6-0.60.7-0.6-1.10.80.6-0.50.3
Reaction time mean minus median0.00.31.50.70.70.30.60.6-0.10.50.50.4-0.30.40.1-0.4-0.3-0.2-1.2
Reaction time mean minus median AUC0.10.40.60.80.80.50.70.7-0.50.70.70.6-0.60.60.3-0.7-0.70.2-0.4
Reaction time num false alarms1.22.13.71.61.61.61.61.6-1.91.51.61.5-1.41.50.9-1.2-1.31.3-0.4
Reaction time num false alarms AUC0.92.13.31.61.61.61.61.6-1.81.61.61.5-1.41.50.9-1.2-1.31.4-0.2
Reaction time trials correct on left0.10.51.5-0.7-0.7-0.8-0.6-0.61.2-0.6-0.6-0.60.7-0.6-1.10.80.6-0.50.3
Reaction time trials on left0.10.51.4-0.6-0.6-0.8-0.6-0.51.2-0.6-0.5-0.60.7-0.6-1.10.80.5-0.50.3
Reaction time mean0.10.20.60.50.50.50.50.5-0.40.40.50.4-0.50.40.8-0.5-0.60.20.4
Reaction time mean AUC0.00.10.30.40.30.30.30.3-0.20.30.30.3-0.30.20.5-0.4-0.50.10.5
Median of all reaction times0.10.10.80.20.20.40.20.2-0.20.20.20.2-0.40.20.7-0.4-0.50.30.9
Reaction time omissions0.30.40.80.80.80.50.80.8-0.50.70.70.7-0.50.7-0.3-0.6-0.90.3-0.7
Reaction time false alarm rate2.23.05.21.91.91.91.81.8-2.31.81.81.8-1.71.81.5-1.6-1.61.6-0.6
Reaction time premature initiation rate0.00.00.10.20.2-0.20.20.20.10.20.30.20.10.20.20.0-0.30.40.2
Reaction time premature initiations0.00.10.5-0.2-0.2-0.6-0.2-0.10.7-0.2-0.1-0.10.5-0.1-0.20.40.10.10.6
Std. dev. reaction times0.20.61.01.01.00.70.90.9-0.60.90.90.8-0.70.80.5-0.8-0.90.4-0.3
Reaction time trials completed0.10.51.4-0.6-0.6-0.8-0.6-0.51.2-0.6-0.5-0.60.7-0.6-1.10.80.5-0.50.3
Reaction time trials AUC0.10.51.4-0.6-0.6-0.8-0.6-0.61.2-0.6-0.6-0.60.7-0.6-1.10.80.6-0.60.2
Run reversals in cocaine runway, females0.60.61.2-0.9-0.9-0.7-0.9-0.80.7-0.9-0.8-0.80.7-0.8-0.50.60.8-0.71.1
Run reversals in cocaine runway, males0.80.81.5-1.0-1.0-0.8-1.0-1.01.2-0.9-1.0-1.00.6-0.9-1.20.60.8-0.9-0.1
Latency to leave start box in cocaine runway0.20.20.5-0.5-0.5-0.1-0.6-0.60.2-0.6-0.6-0.60.1-0.6-0.20.40.7-0.60.0
Latency to leave start box in cocaine runway, F0.10.10.40.20.20.60.10.1-0.60.10.00.1-0.50.00.4-0.10.1-0.1-0.5
Latency to leave start box in cocaine runway, M0.70.60.9-0.9-0.9-0.7-0.9-0.91.0-0.9-0.9-0.90.6-0.8-0.60.70.8-0.70.5
Std. dev. time between licks in bursts0.40.81.20.80.80.80.90.9-1.10.90.90.9-0.70.90.9-0.8-1.01.10.6
Total sessions with >9 infusions2.22.83.6-1.8-1.8-1.8-1.7-1.71.8-1.7-1.7-1.71.6-1.7-1.91.71.6-1.50.5
Short access day 1 total inactive lever presses2.95.86.6-2.6-2.6-2.5-2.5-2.52.4-2.5-2.5-2.52.4-2.5-2.22.52.5-2.21.6
Short access day 10 total inactive lever presses0.10.81.1-0.9-0.9-0.7-0.9-1.00.8-0.9-1.0-0.91.0-0.9-0.70.91.0-1.0-0.1
Short access day 1 total infusions2.03.94.4-2.0-2.0-2.0-2.1-2.11.9-2.0-2.1-2.12.0-2.0-1.92.12.0-2.10.2
Short access day 10 total infusions2.43.95.0-2.1-2.1-1.8-2.1-2.21.8-2.1-2.2-2.11.8-2.1-1.71.92.2-2.20.7
Short access total infusions1.72.52.9-1.7-1.7-1.6-1.7-1.71.5-1.7-1.7-1.71.4-1.7-1.61.51.7-1.70.1
Short access day 1 locomotion1.83.05.9-1.6-1.6-2.0-1.6-1.62.1-1.6-1.6-1.71.8-1.6-2.41.91.6-1.8-0.4
Short access day 10 total locomotion0.62.32.9-1.6-1.6-1.4-1.6-1.61.5-1.6-1.6-1.61.4-1.5-1.71.41.6-1.50.9
Short access total locomotion1.21.82.4-1.4-1.4-1.4-1.4-1.41.5-1.4-1.4-1.41.3-1.3-1.51.31.3-1.20.6
One hour access (0.3 mA shock)2.83.35.2-2.0-2.0-2.2-1.9-1.92.3-1.9-1.8-1.81.9-1.7-1.81.81.6-1.40.3
Compulsive drug intake1.82.74.61.51.51.61.61.6-1.51.61.61.7-1.71.72.1-1.6-1.72.0-0.4
One hour access (shock baseline)2.77.29.0-2.8-2.8-2.9-2.8-2.82.9-2.7-2.7-2.72.8-2.7-3.02.62.6-2.60.9
Social response proportion0.20.23.20.10.1-0.40.00.00.30.00.0-0.00.4-0.00.20.4-0.0-0.3-1.8
Social responses0.30.42.20.60.60.30.60.6-0.50.60.60.6-0.30.60.5-0.2-0.50.4-1.5
Social time0.00.10.2-0.0-0.0-0.3-0.1-0.10.4-0.1-0.1-0.10.3-0.10.30.20.1-0.2-0.5
Soleus weight3.19.110.2-3.2-3.2-3.2-3.1-3.13.1-3.1-3.1-3.03.1-3.0-2.93.12.9-2.62.7
Bone: stiffness0.10.10.80.20.20.30.20.2-0.90.20.20.2-0.20.20.3-0.2-0.20.30.6
Tibialis anterior weight1.03.54.5-2.0-2.0-2.1-1.9-1.91.8-1.9-1.9-1.82.1-1.8-1.92.01.7-1.51.4
Time to tail flick, vehicle, before self-admin0.10.21.2-0.1-0.1-0.5-0.0-0.10.3-0.1-0.1-0.10.5-0.1-1.10.30.2-0.4-0.6
Time to tail flick, vehicle, after self-admin3.06.28.22.72.72.52.62.6-2.12.62.62.6-2.22.61.9-2.4-2.42.2-2.9
Time to tail flick, test, before self-admin0.50.62.0-0.5-0.5-1.2-0.5-0.51.0-0.5-0.5-0.60.9-0.5-1.40.70.5-0.7-0.4
Time to tail flick, test, after self-admin1.41.51.9-1.3-1.3-1.3-1.3-1.30.9-1.3-1.3-1.31.3-1.3-1.11.31.4-1.30.1
Delta time to tail flick, vehicle, before/after SA2.32.53.51.51.51.91.51.5-1.61.51.51.6-1.71.51.8-1.6-1.61.6-0.7
Delta time to tail flick, test, before/after SA1.72.13.1-1.6-1.6-1.1-1.6-1.61.0-1.6-1.6-1.61.5-1.6-0.31.61.8-1.50.7
Tibia length0.82.24.51.41.41.41.51.4-0.91.51.41.5-1.51.50.7-1.6-1.61.4-2.1
Ambulatory time before self-admin0.00.10.5-0.3-0.3-0.2-0.3-0.30.2-0.3-0.3-0.30.6-0.3-0.70.20.3-0.30.6
Ambulatory time after self-admin0.20.30.50.40.40.70.40.5-0.70.40.50.5-0.70.50.7-0.6-0.50.7-0.2
Bone: tissue strength0.70.82.70.70.70.80.80.7-0.40.80.80.8-0.80.91.2-0.7-0.70.8-1.6
Total heroin consumption2.73.24.0-2.0-1.9-2.0-1.9-1.92.0-1.9-1.8-1.82.0-1.8-1.31.71.5-1.31.4
Bone: trabecular number2.24.16.7-2.1-2.1-2.2-2.1-2.12.6-2.0-2.1-2.02.0-2.0-2.12.01.9-1.9-0.5
Bone: trabecular spacing0.71.02.20.90.91.20.90.9-1.50.90.90.9-1.10.90.8-1.1-1.01.10.9
Bone: trabecular thickness0.40.51.1-0.5-0.5-0.8-0.5-0.50.9-0.6-0.6-0.60.8-0.6-0.60.80.7-1.0-1.0
Bone: trabecular tissue density0.10.20.8-0.4-0.4-0.3-0.4-0.40.1-0.4-0.4-0.40.3-0.5-0.30.30.3-0.50.9
Water consumed over 24 hours0.10.20.80.40.40.20.40.5-0.60.40.40.4-0.20.4-0.3-0.2-0.50.50.9
Number of responses in last shaping day1.21.62.2-1.3-1.3-1.4-1.3-1.31.3-1.3-1.3-1.31.5-1.3-0.71.41.3-1.40.3