Hub : Genes

Dnmt3a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS XM_017594268.3 0.01 0.01 1.9e-03 0.01 0.01 0.01 0.01 1.5e-02 7.1e-03 2.4e-02 2.9e-02
2 NAcc alternative TSS XM_017594268.3 0.02 0.01 6.8e-04 0.01 0.01 0.01 0.01 8.8e-03 2.5e-03 7.9e-03 1.3e-02
3 Liver alternative polyA XM_017594268.3 0.04 0.04 4.0e-03 0.02 0.01 0.01 0.02 5.6e-03 6.7e-03 2.0e-02 3.7e-03
4 Brain isoform ratio XM_017594268.3 0.02 0.02 6.9e-03 0.01 0.02 0.01 0.01 1.5e-02 1.1e-02 1.8e-02 1.5e-02
5 NAcc isoform ratio XM_017594268.3 0.02 0.02 1.2e-04 0.02 0.02 0.01 0.02 4.0e-04 3.6e-04 2.3e-03 1.0e-03
6 Liver alternative polyA XM_017594268.3 0.03 0.04 4.1e-03 0.02 0.02 0.02 0.02 1.8e-03 4.6e-03 2.7e-03 2.3e-03
7 Adipose alternative polyA XM_017594268.3 0.04 0.03 2.8e-04 0.02 0.03 0.02 0.02 9.8e-04 4.2e-04 1.3e-03 9.7e-04
8 PL alternative TSS XM_017594268.3 0.02 0.02 9.2e-03 0.01 0.01 0 0.01 1.6e-02 7.8e-03 2.7e-01 2.3e-02
9 PL isoform ratio XM_017594268.3 0.03 0.03 1.6e-04 0.03 0.04 0.03 0.03 8.3e-04 1.0e-04 6.1e-04 9.4e-04
10 Brain gene expression Dnmt3a 0.1 0.09 5.3e-06 0.06 0.06 0.06 0.06 1.3e-06 2.6e-06 2.5e-06 1.8e-06
11 Adipose alternative polyA XM_017594268.3 0.04 0.04 2.2e-04 0.02 0.03 0.02 0.02 9.6e-04 3.4e-04 8.8e-04 9.2e-04
12 Liver mRNA stability Dnmt3a 0.02 0.02 9.4e-03 0.02 0.01 0.02 0.01 5.4e-03 9.7e-03 4.3e-03 1.1e-02
13 BLA gene expression Dnmt3a 0.05 0.04 4.4e-03 0.03 0.02 0.01 0.01 1.6e-02 2.7e-02 1.1e-01 6.1e-02
14 OFC isoform ratio XM_017594268.3 0.18 0.15 8.8e-04 0.18 0.14 0.17 0.15 4.9e-05 3.4e-04 5.9e-05 2.6e-04
15 Adipose gene expression Dnmt3a 0.17 0.1 5.6e-17 0.14 0.15 0.15 0.14 5.3e-15 2.5e-16 6.4e-16 1.3e-15
16 Liver intron excision ratio chr6_32512139_32542146 0.41 0.16 6.9e-03 0.01 0.01 0.03 0.01 3.2e-02 2.1e-02 2.1e-04 3.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bone: apparent density2.64.67.4-2.2-2.2-2.4-2.1-2.2-2.7-2.1-2.1-2.1-2.3-2.12.3-2.3-1.9-2.00.3
Area under the delay curve0.00.10.3-0.1-0.1-0.0-0.1-0.10.3-0.1-0.1-0.1-0.5-0.1-0.2-0.4-0.1-0.1-0.6
BMI with tail2.07.08.42.92.92.72.92.82.72.82.82.72.62.7-2.12.62.62.12.2
BMI without tail2.36.98.72.82.82.92.82.72.92.72.72.72.72.6-2.52.62.62.31.1
Body weight1.98.410.33.23.22.73.23.12.73.13.13.02.73.0-2.02.82.92.42.9
Weight adjusted by age0.10.10.20.50.50.40.40.40.50.40.40.30.30.3-0.50.40.1-0.2-0.0
Bone surface0.50.81.5-0.9-0.9-1.2-0.8-0.8-1.2-0.8-0.8-0.8-1.1-0.80.9-1.1-0.8-0.80.4
Bone volume1.32.43.6-1.6-1.6-1.8-1.5-1.5-1.9-1.5-1.5-1.5-1.8-1.51.7-1.8-1.4-1.40.2
Breakpoint value in progressive ratio session0.60.70.8-0.9-0.9-0.9-0.9-0.9-0.8-0.9-0.9-0.9-0.9-0.90.7-0.6-0.7-0.8-0.3
Number of licking bursts1.01.72.01.41.41.31.41.41.41.41.31.31.31.4-0.91.31.31.11.0
Context. condit. distance diff. score0.20.20.4-0.5-0.5-0.2-0.5-0.5-0.7-0.5-0.5-0.5-0.1-0.50.2-0.2-0.3-0.50.0
Locomotion velocity, session 10.30.40.60.60.60.50.60.70.40.70.70.70.60.7-0.30.60.80.80.1
Locomotion distance, session 10.70.92.5-0.9-0.9-1.1-0.8-0.8-0.8-0.8-0.8-0.8-1.0-0.81.6-0.9-0.6-0.6-1.4
Locomotion velocity, session 20.10.20.60.50.50.40.50.40.80.40.40.30.30.40.00.40.20.10.3
Locomotion distance, session 20.10.22.20.10.1-0.20.10.10.20.10.10.1-0.20.10.8-0.10.20.1-1.5
Locomotion velocity, session 30.00.00.1-0.1-0.10.1-0.1-0.10.3-0.0-0.1-0.10.1-0.1-0.10.0-0.0-0.1-0.1
Locomotion distance, session 30.00.00.10.20.20.20.20.20.30.20.20.20.30.2-0.10.30.30.3-0.1
Stereotopy head waving bouts, day 32.02.43.1-1.6-1.6-1.6-1.7-1.6-1.8-1.6-1.6-1.6-1.5-1.61.0-1.6-1.6-1.4-1.0
Stereotopy head waving duration, day 30.30.40.5-0.7-0.7-0.6-0.7-0.7-0.5-0.7-0.7-0.7-0.6-0.70.1-0.6-0.7-0.6-0.2
Locomotion velocity, session 70.00.00.20.00.10.20.10.00.40.10.00.00.10.00.20.10.00.0-0.4
Locomotion distance, session 71.01.32.91.01.01.41.01.01.71.01.01.01.31.0-1.31.30.91.0-0.7
Stereotopy head waving bouts, day 70.00.00.1-0.00.00.00.00.0-0.20.10.00.10.10.1-0.20.00.10.10.2
Stereotopy head waving duration, day 70.30.40.5-0.6-0.6-0.6-0.6-0.7-0.7-0.6-0.6-0.6-0.6-0.60.4-0.7-0.6-0.60.1
Locomotion velocity, session 80.50.61.4-0.7-0.7-0.8-0.7-0.7-1.2-0.7-0.7-0.7-0.6-0.71.0-0.5-0.7-0.80.8
Locomotion distance, session 80.50.74.5-0.9-0.9-0.5-0.8-0.8-0.5-0.8-0.8-0.7-0.5-0.80.6-0.5-0.5-0.4-2.1
Degree of sensitization distance0.90.91.71.01.01.11.01.01.30.91.00.91.00.9-1.21.00.80.8-0.1
Degree of sensitization stereotypy0.30.30.40.60.60.50.60.60.40.60.60.60.50.6-0.60.50.70.60.2
Conditioned locomotion2.73.13.8-1.8-1.8-1.7-1.8-1.8-1.4-1.8-1.8-1.8-1.8-1.91.2-1.9-2.0-1.8-1.5
Cocaine response after cond. corrected0.10.10.2-0.4-0.4-0.2-0.4-0.4-0.3-0.4-0.4-0.4-0.3-0.40.4-0.3-0.4-0.40.0
Cocaine response after cond. not corrected0.60.70.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.80.8-0.9-0.8-0.8-0.5
Cocaine response before conditioning2.22.73.9-1.6-1.6-1.9-1.6-1.6-1.5-1.6-1.6-1.6-2.0-1.61.4-1.9-1.6-1.6-1.4
Saline control response1.31.82.9-1.3-1.3-1.6-1.3-1.3-1.7-1.3-1.3-1.3-1.5-1.31.1-1.6-1.4-1.2-0.3
Bone: connectivity density1.62.54.7-1.6-1.6-1.8-1.6-1.6-2.2-1.5-1.6-1.6-1.7-1.51.4-1.7-1.5-1.60.3
Bone: cortical apparent density0.10.10.5-0.2-0.2-0.5-0.3-0.2-0.7-0.2-0.2-0.2-0.5-0.20.1-0.5-0.1-0.20.1
Bone: cortical area0.00.00.10.10.10.00.10.10.40.10.10.10.00.10.20.00.20.20.0
Bone: cortical porosity3.33.64.4-1.9-1.9-2.0-1.9-1.9-2.1-1.9-1.9-2.0-2.0-1.91.9-2.0-2.0-2.10.4
Bone: cortical porosity3.03.34.1-1.8-1.8-1.9-1.8-1.8-2.0-1.8-1.8-1.9-1.9-1.82.0-1.9-1.9-2.00.5
Bone: cortical thickness0.20.30.70.60.60.50.60.60.80.60.60.60.50.6-0.40.50.70.70.1
Bone: cortical thickness0.40.51.5-0.7-0.7-0.8-0.7-0.6-0.6-0.7-0.6-0.7-0.8-0.71.2-0.8-0.4-0.6-0.6
Bone: cortical tissue density0.10.10.4-0.2-0.2-0.5-0.2-0.1-0.7-0.2-0.1-0.1-0.5-0.10.1-0.4-0.0-0.10.3
Condit. Reinf. active minus inactive responses2.32.63.11.71.71.61.71.71.51.71.71.71.61.7-1.11.61.71.51.3
Condit. Reinf. active-inactive response ratio2.52.74.21.71.71.61.61.61.41.61.61.61.71.6-1.41.71.71.42.1
Condit. Reinf. active responses0.20.20.30.50.50.30.50.50.40.50.50.50.40.50.10.40.60.40.1
Condit. Reinf. inactive responses1.61.93.4-1.3-1.3-1.5-1.3-1.2-1.2-1.3-1.2-1.3-1.5-1.31.7-1.5-1.3-1.2-1.8
Incentive salience index mean0.30.41.50.70.70.50.70.70.40.70.60.60.60.60.10.50.70.31.2
Condit. Reinf. lever presses1.01.43.4-1.1-1.1-1.2-1.1-1.1-1.2-1.1-1.1-1.2-1.2-1.11.8-1.3-1.2-1.30.1
Condit. Reinf. active minus inactive responses0.91.21.5-1.1-1.1-1.2-1.1-1.1-1.0-1.1-1.1-1.1-1.2-1.10.9-1.2-1.1-1.1-0.6
Condit. Reinf. active-inactive response ratio0.50.50.8-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.8-0.8-0.7-0.80.8-0.8-0.8-0.90.1
Condit. Reinf. active responses0.60.81.3-0.8-0.8-1.1-0.9-0.8-0.9-0.9-0.8-0.9-1.2-0.90.8-1.1-0.8-0.8-0.8
Condit. Reinf. inactive responses0.20.31.3-0.4-0.4-0.6-0.4-0.3-0.3-0.4-0.3-0.4-0.7-0.40.6-0.6-0.3-0.3-1.2
Condit. Reinf. lever presses0.91.31.4-1.1-1.2-1.1-1.2-1.1-0.9-1.2-1.1-1.1-1.2-1.21.1-1.1-1.0-1.1-1.2
Condit. Reinf. lever reinforcers received0.60.81.3-0.8-0.8-1.1-0.8-0.8-0.9-0.9-0.8-0.8-1.1-0.90.9-1.1-0.8-0.9-0.7
Conditioned reinforcement - actives3.35.67.6-2.4-2.4-2.6-2.5-2.4-2.4-2.4-2.4-2.4-2.4-2.42.8-2.3-2.3-2.2-1.0
Conditioned reinforcement - inactives5.17.58.6-2.9-2.9-2.9-2.9-2.9-2.9-2.8-2.8-2.8-2.8-2.72.9-2.7-2.7-2.4-1.1
Conditioned locomotion2.53.35.4-1.8-1.8-2.2-1.8-1.8-2.3-1.7-1.7-1.8-2.0-1.72.1-1.9-1.7-1.70.2
Patch foraging indifference point 0 sec0.30.61.00.70.70.90.70.71.00.80.80.80.80.8-0.40.90.81.0-0.1
Patch foraging indifference point AUC0.10.10.7-0.0-0.00.40.0-0.00.5-0.0-0.00.00.4-0.0-0.40.3-0.00.1-0.8
Delay disc. indifference point, 0s delay0.40.51.20.60.60.60.70.70.90.70.70.70.20.7-1.10.20.50.90.0
Delay disc. indifference point, 16s delay0.00.00.10.10.10.10.10.10.10.10.10.1-0.10.1-0.2-0.10.10.1-0.4
Delay disc. indifference point, 2s delay0.10.10.40.20.20.20.20.20.10.30.20.20.20.3-0.60.20.30.30.6
Delay disc. indifference point, 24s delay2.62.93.6-1.8-1.7-1.9-1.7-1.7-1.9-1.7-1.7-1.7-1.9-1.71.9-1.5-1.6-1.6-0.8
Delay disc. indifference point, 4s delay0.20.21.10.30.30.30.30.30.70.20.30.3-0.10.2-0.70.10.30.3-1.1
Delay disc. indifference point, 8s delay0.10.10.4-0.1-0.10.0-0.1-0.20.4-0.1-0.2-0.1-0.6-0.2-0.3-0.4-0.3-0.1-0.6
Indifference point function ln k1.42.53.1-1.7-1.7-1.6-1.6-1.6-1.8-1.6-1.6-1.6-1.7-1.61.5-1.7-1.5-1.5-0.5
Indifference point function log k1.42.53.1-1.7-1.7-1.6-1.6-1.6-1.8-1.6-1.6-1.6-1.7-1.61.5-1.7-1.5-1.5-0.5
Patch foraging total patch changes 0 sec0.30.61.10.70.70.90.70.71.00.70.80.80.80.8-0.40.90.71.0-0.4
Patch foraging total patch changes 12 sec1.11.52.61.31.31.41.21.21.61.21.21.21.31.1-1.11.41.11.00.5
Patch foraging total patch changes 18 sec0.60.91.11.01.00.91.01.01.01.01.01.00.91.0-0.91.01.01.00.1
Patch foraging total patch changes 24 sec1.01.73.61.31.31.51.31.31.91.31.31.31.41.3-1.11.41.21.3-0.2
Patch foraging total patch changes 6 sec1.72.64.81.51.61.91.61.52.21.61.61.61.71.6-1.51.81.51.70.1
Patch foraging time to switch 0 sec0.40.91.81.01.00.80.90.90.70.90.90.90.80.9-1.30.90.90.71.2
Patch foraging water rate 0 sec1.42.93.8-1.8-1.8-1.8-1.7-1.7-1.6-1.7-1.6-1.6-1.8-1.61.9-1.8-1.5-1.2-2.0
Patch foraging water rate 12 sec0.00.10.10.20.20.30.20.20.10.20.20.20.20.3-0.00.10.30.30.3
Patch foraging water rate 18 sec1.32.03.0-1.6-1.5-1.5-1.5-1.4-1.5-1.4-1.4-1.3-1.5-1.31.6-1.6-1.1-0.8-1.7
Patch foraging water rate 24 sec0.10.10.20.40.40.20.40.40.20.40.40.30.20.30.00.10.30.20.5
Patch foraging water rate 6 sec0.40.61.9-0.8-0.8-0.8-0.8-0.7-0.6-0.7-0.7-0.7-0.7-0.70.8-0.8-0.5-0.3-1.4
Seeking ratio, delayed vs. immediate footshock0.20.21.50.40.40.60.40.40.40.40.30.30.30.3-0.40.20.10.01.2
Distance traveled before self-admin0.10.10.5-0.2-0.2-0.2-0.3-0.2-0.1-0.3-0.2-0.3-0.4-0.30.6-0.2-0.3-0.2-0.7
Distance traveled after self-admin0.70.81.20.80.81.00.80.90.90.90.90.91.10.9-1.01.00.91.10.3
Extensor digitorum longus weight2.39.111.0-3.1-3.1-3.3-3.0-3.1-3.2-3.0-3.1-3.1-3.2-3.03.3-3.2-3.0-2.9-0.8
Bone: elastic displacement1.51.73.9-1.4-1.4-1.4-1.4-1.4-2.0-1.3-1.3-1.3-1.2-1.31.2-1.2-1.1-1.20.1
Bone: elastic work0.50.72.1-0.9-0.9-0.8-0.9-0.9-1.5-0.8-0.9-0.8-0.6-0.70.7-0.6-0.5-0.60.7
Bone: endosteal estimation0.10.30.5-0.6-0.6-0.5-0.5-0.5-0.6-0.5-0.6-0.5-0.3-0.50.7-0.3-0.5-0.4-0.3
Bone: endosteal perimeter0.00.10.3-0.1-0.1-0.2-0.1-0.1-0.4-0.1-0.1-0.1-0.1-0.10.4-0.1-0.1-0.20.6
Epididymis fat weight16.656.965.38.18.17.58.07.97.17.97.97.77.57.7-6.77.67.46.76.7
Delta time in closed arm before/after self-admin0.10.10.30.20.20.60.10.10.50.10.10.20.30.1-0.50.20.20.2-0.4
Delta time in open arm before/after self-admin0.00.00.20.20.2-0.00.20.2-0.00.20.10.1-0.00.10.50.20.1-0.10.5
Diff in mean of infusions in LGA sessions0.20.31.80.50.50.60.50.40.10.50.40.30.60.4-0.30.60.40.11.3
Delay discount exponential model param0.10.20.50.30.30.30.30.30.00.30.40.40.70.4-0.00.50.40.30.6
Extinction: sum of active levers before priming0.30.40.8-0.5-0.5-0.3-0.6-0.6-0.2-0.6-0.6-0.7-0.8-0.70.6-0.6-0.8-0.90.4
Active lever presses in extinction session 62.12.13.6-1.4-1.4-1.5-1.4-1.4-1.6-1.4-1.4-1.5-1.6-1.41.9-1.4-1.4-1.70.9
Bone: final force0.10.22.30.20.20.00.20.10.00.20.10.20.10.20.10.10.20.01.5
Bone: final moment0.10.12.10.10.1-0.00.20.1-0.00.20.10.10.00.20.00.00.20.01.4
Food consumed during 24 hour testing period0.10.22.00.00.00.30.10.10.60.10.10.10.30.10.20.30.20.4-1.4
Glucose0.91.42.01.21.21.31.21.21.11.21.21.21.21.2-1.41.31.21.11.0
Heart weight1.21.93.71.41.41.51.41.41.51.41.41.41.31.3-1.91.51.41.40.4
Delay discount hyperbolic model param0.00.00.30.10.10.00.10.1-0.20.10.10.10.40.10.30.30.10.00.5
Intermittent access intake day 1-15 change0.71.42.3-1.3-1.3-1.4-1.3-1.2-1.5-1.2-1.1-1.1-0.9-1.11.1-1.0-0.8-0.5-1.5
Intermittent access intake escalation0.30.72.4-1.0-1.0-1.0-0.9-0.8-1.1-0.9-0.8-0.7-0.5-0.70.6-0.6-0.5-0.1-1.6
Intermittent access intake escalation 20.20.22.0-0.5-0.5-0.5-0.4-0.3-0.6-0.4-0.3-0.2-0.2-0.30.0-0.2-0.00.4-1.4
Intermitt. access day 1 inactive lever presses0.41.51.9-1.3-1.2-1.0-1.2-1.3-0.9-1.2-1.3-1.3-1.3-1.31.3-1.3-1.4-1.3-0.3
Intermitt. access day 15 inactive lever presses0.71.41.9-1.2-1.2-1.0-1.2-1.3-1.0-1.2-1.3-1.3-1.1-1.20.9-1.1-1.4-1.40.4
Intermitt. access escalation Index4.05.710.72.42.42.52.42.42.62.42.42.42.22.4-3.32.22.42.40.4
Intermittent access day 1 total infusions1.52.43.2-1.6-1.6-1.3-1.6-1.7-1.1-1.6-1.7-1.7-1.4-1.71.4-1.5-1.8-1.8-0.7
Intermittent access day 15 total infusions1.92.93.4-1.8-1.9-1.7-1.8-1.8-1.7-1.8-1.8-1.8-1.5-1.81.5-1.5-1.7-1.5-1.5
Intermittent access terminal intake (last 3 days)3.03.94.7-2.2-2.2-1.9-2.1-2.1-1.9-2.1-2.1-2.1-1.7-2.11.9-1.9-1.9-1.7-1.6
Intermittent access total infusions3.74.34.9-2.2-2.2-2.1-2.2-2.2-2.0-2.2-2.2-2.2-2.0-2.22.2-2.0-2.1-2.1-0.7
Intermittent access day 1 locomotion2.43.03.4-1.8-1.8-1.6-1.8-1.8-1.6-1.8-1.8-1.8-1.7-1.81.8-1.7-1.8-1.7-1.2
Intermittent access day 15 total locomotion0.10.10.3-0.5-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.3-0.2-0.30.6-0.1-0.2-0.0-0.4
Intermittent access total locomotion1.61.93.4-1.5-1.4-1.5-1.4-1.4-1.5-1.4-1.4-1.4-1.3-1.41.8-1.2-1.2-1.1-1.0
Intermittent access standard deviation1.02.23.1-1.6-1.6-1.6-1.6-1.5-1.5-1.5-1.5-1.5-1.2-1.51.8-1.3-1.4-1.2-1.1
Left kidney weight0.10.71.7-0.6-0.6-0.7-0.7-0.8-0.8-0.7-0.8-0.9-0.8-0.81.2-0.7-1.0-1.30.3
Right kidney weight0.10.53.70.70.70.60.70.60.30.70.60.50.40.50.10.60.3-0.11.9
Cocaine induced anxiety0.10.10.3-0.3-0.4-0.6-0.4-0.3-0.5-0.3-0.3-0.3-0.2-0.30.1-0.3-0.2-0.2-0.0
Post-drug Anxiety1.41.52.31.21.21.11.31.21.41.21.31.31.51.3-1.11.41.31.30.1
Baseline Anxiety3.23.74.92.02.02.12.02.02.22.02.02.02.02.0-1.62.02.01.90.3
Tail length0.00.10.6-0.3-0.3-0.3-0.3-0.3-0.5-0.3-0.2-0.2-0.3-0.20.2-0.2-0.10.1-0.7
Length with tail0.10.21.70.40.4-0.20.40.4-0.20.40.40.4-0.10.40.70.20.40.21.3
Length without tail0.20.53.1-0.1-0.1-0.7-0.1-0.1-0.6-0.1-0.1-0.2-0.5-0.21.7-0.4-0.2-0.71.8
Times rat made contact with spout0.91.02.6-1.0-1.0-1.1-0.9-0.9-1.3-0.9-0.9-1.0-1.0-0.91.6-1.0-0.9-0.9-0.1
Lifetime Intake3.94.75.4-2.3-2.3-2.2-2.3-2.3-2.1-2.3-2.3-2.3-2.1-2.32.3-2.1-2.3-2.2-0.6
Liver weight, left1.93.24.61.81.81.81.81.81.21.81.81.81.91.8-1.62.01.81.72.1
Liver weight, right2.95.17.52.42.42.22.42.32.02.42.32.32.12.3-1.82.32.12.02.7
Locomotor activity0.81.25.11.21.21.01.21.10.91.11.11.00.91.1-0.20.90.90.62.3
Locomotor testing distance0.40.83.11.01.00.81.00.90.70.90.90.80.80.9-0.30.60.60.41.7
Locomotor testing rearing0.30.51.6-0.4-0.4-0.6-0.5-0.5-0.4-0.5-0.6-0.6-0.8-0.61.0-0.9-0.8-1.01.3
Locomotion in novel chamber0.30.44.70.50.50.20.50.40.20.40.30.30.10.30.7-0.00.2-0.22.2
Locomotion in novel chamber post-restriction1.72.84.51.71.71.31.71.81.51.71.81.81.31.8-2.11.51.81.90.4
Fecal boli incidents, locomotor time 12.23.13.7-1.9-1.9-1.7-1.9-1.9-1.5-1.9-1.9-1.9-1.7-1.91.6-1.6-1.8-1.6-1.5
Change in fecal boli incidents, locomotor task3.83.85.52.02.02.01.92.02.01.92.02.02.01.9-2.31.81.81.81.2
Time >=10cm from walls, locomotor time 10.50.50.9-0.7-0.7-0.9-0.7-0.7-0.7-0.7-0.7-0.7-0.8-0.80.7-0.7-0.7-0.8-0.6
Bouts of movement, locomotor time 10.40.45.7-0.2-0.20.3-0.1-0.10.9-0.2-0.1-0.0-0.3-0.10.20.1-0.10.4-2.4
Total resting periods, locomotor time 10.50.56.7-0.3-0.20.2-0.2-0.20.9-0.2-0.1-0.1-0.3-0.20.20.1-0.10.4-2.6
Rest time, locomotor task time 10.40.52.10.30.30.80.40.41.50.40.40.50.30.4-0.80.70.50.8-1.3
Distance moved, locomotor task time 10.30.55.30.40.4-0.10.40.4-0.90.40.40.30.70.40.20.20.2-0.12.3
Vertical activity count, locomotor time 10.10.32.40.20.2-0.50.20.2-1.20.20.20.10.20.20.2-0.00.1-0.01.5
Time >=10cm from walls, locomotor time 21.21.72.5-1.4-1.4-1.3-1.4-1.4-1.6-1.4-1.4-1.4-1.1-1.40.9-1.2-1.5-1.50.2
Bouts of movement, locomotor time 20.40.74.00.40.40.60.50.51.40.50.60.60.40.5-0.70.70.71.0-2.0
Total resting periods, locomotor time 20.40.73.30.50.50.70.50.61.50.50.60.60.40.5-0.80.80.71.0-1.8
Rest time, locomotor task time 20.00.00.2-0.1-0.10.1-0.0-0.00.5-0.0-0.0-0.0-0.5-0.00.1-0.10.00.1-0.3
Distance moved, locomotor task time 20.30.33.9-0.0-0.0-0.2-0.0-0.1-1.00.0-0.0-0.00.50.0-0.00.1-0.1-0.22.0
Vertical activity count, locomotor time 20.30.43.4-0.3-0.3-0.4-0.4-0.4-1.1-0.3-0.4-0.3-0.0-0.3-0.3-0.2-0.5-0.51.8
Light reinforcement 10.41.01.7-1.0-1.0-1.0-1.0-1.0-0.8-1.0-1.0-0.9-1.1-1.00.6-1.1-0.9-0.8-1.3
Light reinforcement 21.21.93.6-1.4-1.4-1.4-1.4-1.3-1.4-1.4-1.3-1.3-1.5-1.30.4-1.4-1.4-1.0-1.9
Bone: marrow area0.10.30.6-0.6-0.6-0.5-0.5-0.5-0.6-0.5-0.5-0.5-0.3-0.50.7-0.4-0.5-0.4-0.3
Bone: maximum diameter0.00.00.1-0.2-0.2-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.3-0.1-0.00.0-0.3
Bone: maximum force0.00.10.4-0.1-0.1-0.2-0.1-0.10.0-0.1-0.1-0.1-0.2-0.10.4-0.2-0.1-0.20.7
Bone: maximum moment0.00.10.4-0.2-0.2-0.3-0.2-0.2-0.0-0.1-0.2-0.2-0.3-0.10.3-0.3-0.1-0.20.6
Mean time between licks in bursts0.71.82.41.31.31.41.41.41.41.41.31.41.41.4-1.51.51.51.50.4
Mean num. licks in bursts1.52.33.5-1.6-1.6-1.6-1.6-1.6-1.9-1.6-1.6-1.5-1.5-1.51.4-1.5-1.4-1.3-0.8
Cd content in liver0.10.10.20.50.40.30.40.40.50.40.40.40.40.3-0.10.40.40.2-0.3
Co content in liver4.75.56.8-2.3-2.3-2.6-2.3-2.3-2.3-2.4-2.3-2.4-2.5-2.42.6-2.3-2.3-2.6-1.4
Cu content in liver0.20.30.8-0.3-0.3-0.5-0.4-0.40.0-0.5-0.4-0.5-0.6-0.60.5-0.6-0.6-0.9-0.6
Fe content in liver2.22.64.4-1.6-1.6-1.8-1.6-1.6-1.8-1.6-1.6-1.6-1.6-1.62.1-1.6-1.5-1.6-0.6
K content in liver0.40.31.40.60.60.60.60.61.20.50.50.50.50.5-0.50.60.50.30.4
Mg content in liver0.10.10.60.10.00.10.00.00.7-0.00.00.0-0.0-0.1-0.5-0.0-0.0-0.1-0.8
Mn content in liver0.60.71.20.80.80.80.80.81.10.80.80.80.80.8-1.00.80.70.80.6
Na content in liver2.22.43.1-1.8-1.7-1.6-1.7-1.7-1.7-1.7-1.7-1.6-1.4-1.61.2-1.5-1.6-1.4-0.2
Rb content in liver0.10.10.30.40.40.40.40.40.50.40.40.40.40.3-0.40.40.30.20.0
Se content in liver0.10.10.30.40.40.10.30.40.30.30.40.30.10.30.00.20.20.10.6
Sr content in liver0.10.10.2-0.3-0.3-0.2-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.30.4-0.2-0.2-0.1-0.2
Zn content in liver0.70.81.81.01.00.90.91.01.30.90.90.80.90.7-1.01.00.90.5-0.5
Bone: minimum diameter0.61.11.81.11.11.21.11.11.41.11.01.01.11.0-0.51.10.90.80.7
Time in familiar zone, hab. session 11.01.01.81.11.11.21.01.01.41.01.00.91.10.9-0.91.10.70.70.8
Time in novel zone, hab. session 10.30.31.10.60.60.30.60.50.10.60.60.50.40.6-0.30.40.70.41.0
Total zone transitions, hab. session 10.30.41.3-0.7-0.7-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.5-0.51.1-0.5-0.3-0.3-0.9
Total locomotion distance, hab. session 11.01.42.6-1.2-1.2-1.3-1.2-1.1-1.2-1.1-1.1-1.1-1.2-1.11.6-1.1-0.9-0.8-1.4
Locomotion velocity, hab. session 11.82.54.3-1.7-1.7-1.6-1.6-1.6-1.5-1.6-1.5-1.5-1.5-1.51.8-1.5-1.3-1.1-2.1
Time in familiar zone, hab. session 20.40.40.80.60.60.90.60.60.80.60.60.60.80.6-0.80.80.50.70.3
Time in novel zone, hab. session 20.10.10.50.30.3-0.30.20.2-0.20.20.20.1-0.20.10.1-0.10.2-0.20.7
Total zone transitions, hab. session 20.10.10.40.10.10.10.20.2-0.20.20.20.20.20.30.60.30.40.6-0.2
Total locomotion distance, hab. session 20.10.10.30.20.20.10.30.3-0.20.30.30.30.20.40.50.30.50.6-0.0
Locomotion velocity, hab. session 20.10.10.50.00.0-0.10.10.1-0.40.10.20.20.00.20.70.10.40.4-0.2
Novel to familiar place preference ratio0.20.20.50.30.40.30.40.40.50.40.50.50.20.50.00.30.50.7-0.5
Novelty place preference0.40.40.80.60.60.50.70.70.80.70.70.70.30.7-0.10.40.80.9-0.3
Time in novel zone, NPP test0.30.40.60.60.60.50.70.70.80.70.70.70.30.7-0.00.40.70.8-0.2
Total zone transitions, NPP test1.01.43.3-1.2-1.2-1.2-1.1-1.1-1.0-1.1-1.1-1.2-1.2-1.11.8-1.1-1.1-1.1-1.1
Total locomotion distance, NPP test1.62.24.0-1.5-1.5-1.6-1.4-1.4-1.3-1.4-1.4-1.4-1.5-1.42.0-1.5-1.3-1.3-1.5
Locomotion velocity, NPP test2.12.94.7-1.8-1.8-1.9-1.7-1.7-1.8-1.7-1.7-1.7-1.8-1.62.2-1.7-1.5-1.4-1.2
Intraocular pressure3.44.96.02.42.42.12.42.42.02.32.42.42.02.3-2.41.92.22.20.9
Delta distance traveled before/after self-admin2.12.34.01.41.41.61.41.41.31.41.41.52.01.5-1.61.71.51.61.2
Delta ambulatory time before/after self-admin0.40.51.30.50.50.70.50.50.50.60.60.61.10.7-1.10.70.70.90.7
Parametrial fat weight22.452.762.07.57.57.97.47.37.17.47.37.27.77.3-7.17.56.96.46.5
Pavlov. Cond. lever latency0.60.71.20.80.80.90.80.81.00.80.80.80.80.8-1.10.80.90.9-0.2
Pavlov. Cond. magazine entry latency0.00.00.3-0.0-0.0-0.20.00.0-0.20.00.0-0.0-0.1-0.00.5-0.2-0.0-0.10.2
Pavlov. Cond. change in total contacts0.10.10.1-0.3-0.3-0.1-0.2-0.3-0.1-0.3-0.3-0.3-0.1-0.30.4-0.1-0.3-0.3-0.3
Pavlov. Cond. index score0.10.20.5-0.3-0.3-0.5-0.3-0.3-0.5-0.3-0.3-0.4-0.4-0.30.7-0.5-0.4-0.50.2
Pavlov. Cond. latency score0.10.10.4-0.3-0.2-0.4-0.2-0.2-0.6-0.2-0.2-0.3-0.3-0.20.6-0.4-0.3-0.30.4
Pavlov. Cond. lever contacts0.60.71.1-0.8-0.8-0.9-0.8-0.8-1.0-0.8-0.8-0.8-0.8-0.81.1-0.9-0.9-0.90.2
Pavlov. Cond. magazine entry number0.10.20.90.40.30.50.30.30.40.30.30.30.40.3-0.90.50.30.20.4
Pavlov. Cond. intertrial magazine entries1.51.82.7-1.3-1.3-1.5-1.4-1.3-1.4-1.4-1.4-1.4-1.4-1.40.9-1.3-1.4-1.6-0.2
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-0.7-0.7-0.8-0.7-0.7-0.8-0.7-0.7-0.7-0.7-0.71.0-0.8-0.8-0.8-0.1
Pavlov. Cond. response bias0.91.11.9-1.0-1.0-1.1-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.01.4-1.1-1.1-1.1-0.5
Pavlov. Cond. lever latency0.50.73.00.80.80.60.80.80.20.80.80.80.70.8-0.60.70.70.61.7
Pavlov. Cond. magazine entry latency0.00.00.10.20.20.10.10.20.20.20.20.20.10.2-0.30.20.20.2-0.3
Pavlov. Cond. change in total contacts0.00.00.0-0.2-0.20.0-0.2-0.2-0.0-0.2-0.2-0.20.0-0.20.10.0-0.1-0.1-0.1
Pavlov. Cond. index score0.20.30.5-0.6-0.6-0.4-0.6-0.6-0.3-0.6-0.6-0.6-0.5-0.60.4-0.4-0.5-0.5-0.7
Pavlov. Cond. latency score0.20.30.7-0.6-0.6-0.4-0.6-0.6-0.3-0.6-0.6-0.6-0.5-0.60.3-0.4-0.5-0.5-0.9
Pavlov. Cond. lever contacts0.30.42.2-0.6-0.6-0.4-0.6-0.6-0.0-0.6-0.6-0.6-0.5-0.60.4-0.4-0.5-0.5-1.5
Pavlov. Cond. magazine entry number0.10.10.2-0.4-0.4-0.4-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.40.4-0.5-0.4-0.2-0.3
Pavlov. Cond. intertrial magazine entries1.72.63.41.71.71.51.71.70.81.71.71.71.71.8-0.91.81.91.81.5
Pavlov. Cond. lever-magazine prob. diff.0.00.10.2-0.3-0.3-0.1-0.3-0.3-0.1-0.3-0.3-0.3-0.2-0.20.2-0.1-0.1-0.2-0.4
Pavlov. Cond. response bias0.40.61.9-0.8-0.8-0.6-0.8-0.8-0.3-0.8-0.8-0.8-0.7-0.80.6-0.6-0.7-0.7-1.4
Time in closed arm before self-admin0.10.10.50.40.4-0.10.40.4-0.40.40.40.40.10.40.70.30.20.30.6
Time in closed arm after self-admin0.70.72.30.90.90.70.90.90.20.90.90.90.80.90.20.70.70.61.5
Time in open arm before self-admin0.00.10.40.00.00.3-0.0-0.00.5-0.0-0.0-0.00.2-0.0-0.60.00.20.0-0.0
Time in open arm after self-admin0.10.10.5-0.3-0.3-0.3-0.3-0.30.1-0.3-0.3-0.3-0.2-0.3-0.1-0.1-0.1-0.2-0.7
Bone: periosteal estimation0.10.30.7-0.6-0.6-0.5-0.5-0.5-0.3-0.5-0.6-0.5-0.4-0.50.9-0.4-0.5-0.4-0.7
Bone: periosteal perimeter0.00.00.1-0.1-0.1-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.3-0.1-0.1-0.1-0.0
Bone: post-yield work1.52.32.9-1.5-1.5-1.6-1.6-1.6-1.2-1.5-1.6-1.6-1.5-1.61.7-1.5-1.6-1.6-0.5
Progressive ratio test 1 active lever presses2.02.53.1-1.7-1.7-1.5-1.7-1.7-1.4-1.7-1.8-1.7-1.4-1.71.6-1.5-1.7-1.7-0.5
Progressive ratio test 1 breakpoint2.12.63.2-1.7-1.7-1.4-1.7-1.8-1.4-1.7-1.8-1.8-1.4-1.71.6-1.4-1.7-1.7-0.5
Progressive ratio test 1 inactive lever presses3.45.06.3-2.3-2.3-2.0-2.3-2.4-1.9-2.3-2.4-2.4-2.2-2.42.3-2.0-2.5-2.5-0.7
Progressive ratio test 2 active lever presses3.13.64.5-2.0-2.0-2.0-2.0-2.0-2.1-2.0-2.0-1.9-1.9-1.92.1-1.7-1.8-1.7-0.9
Progressive ratio test 2 breakpoint2.93.34.0-2.0-2.0-1.9-1.9-1.9-2.0-1.9-1.9-1.9-1.8-1.91.9-1.6-1.7-1.6-1.0
Progressive ratio test 2 inactive lever presses2.64.35.2-2.3-2.3-2.2-2.2-2.2-2.2-2.2-2.2-2.2-1.9-2.12.1-1.8-2.0-1.8-0.7
Incentive Sensitization - Responses2.12.93.6-1.8-1.8-1.8-1.8-1.8-1.9-1.8-1.8-1.8-1.7-1.81.7-1.6-1.6-1.6-0.9
Incentive Sensitization - Breakpoint1.82.32.8-1.6-1.6-1.6-1.6-1.6-1.7-1.6-1.6-1.6-1.5-1.61.5-1.4-1.5-1.4-0.9
Sum of active levers in priming session hrs 5-60.10.10.40.30.30.30.30.30.40.30.30.30.10.3-0.30.40.30.4-0.6
Progressive ratio0.10.11.60.20.2-0.10.20.2-0.30.20.10.1-0.20.10.50.10.2-0.11.3
Food seeking constrained by brief footshock13.016.019.7-4.0-4.0-4.1-4.1-4.1-4.1-4.1-4.2-4.2-3.7-4.24.2-3.9-4.1-4.4-1.6
Seeking ratio, punishment vs. effort1.52.13.7-1.5-1.5-1.3-1.6-1.5-1.2-1.6-1.5-1.5-1.1-1.51.0-1.3-1.5-1.3-1.9
Retroperitoneal fat weight36.3154.7174.013.213.212.913.012.912.112.912.812.712.612.6-12.112.412.111.010.4
Reaction time number correct0.30.51.5-0.7-0.7-0.8-0.6-0.6-1.2-0.6-0.6-0.6-0.7-0.61.1-0.8-0.6-0.5-0.3
Reaction time mean minus median0.10.31.50.70.70.30.60.60.10.50.50.40.30.4-0.10.40.3-0.21.2
Reaction time mean minus median AUC0.20.40.60.80.80.50.70.70.50.70.70.60.60.6-0.30.70.70.20.4
Reaction time num false alarms1.52.13.71.61.61.61.61.61.91.51.61.51.41.5-0.91.21.31.30.4
Reaction time num false alarms AUC1.32.13.31.61.61.61.61.61.81.61.61.51.41.5-0.91.21.31.40.2
Reaction time trials correct on left0.30.51.5-0.7-0.7-0.8-0.6-0.6-1.2-0.6-0.6-0.6-0.7-0.61.1-0.8-0.6-0.5-0.3
Reaction time trials on left0.30.51.4-0.6-0.6-0.8-0.6-0.5-1.2-0.6-0.5-0.6-0.7-0.61.1-0.8-0.5-0.5-0.3
Reaction time mean0.10.20.60.50.50.50.50.50.40.40.50.40.50.4-0.80.50.60.2-0.4
Reaction time mean AUC0.10.10.30.40.30.30.30.30.20.30.30.30.30.2-0.50.40.50.1-0.5
Median of all reaction times0.10.10.80.20.20.40.20.20.20.20.20.20.40.2-0.70.40.50.3-0.9
Reaction time omissions0.30.40.80.80.80.50.80.80.50.70.70.70.50.70.30.60.90.30.7
Reaction time false alarm rate2.23.05.21.91.91.91.81.82.31.81.81.81.71.8-1.51.61.61.60.6
Reaction time premature initiation rate0.00.00.10.20.2-0.20.20.2-0.10.20.30.2-0.10.2-0.2-0.00.30.4-0.2
Reaction time premature initiations0.10.10.5-0.2-0.2-0.6-0.2-0.1-0.7-0.2-0.1-0.1-0.5-0.10.2-0.4-0.10.1-0.6
Std. dev. reaction times0.30.61.01.01.00.70.90.90.60.90.90.80.70.8-0.50.80.90.40.3
Reaction time trials completed0.30.51.4-0.6-0.6-0.8-0.6-0.5-1.2-0.6-0.5-0.6-0.7-0.61.1-0.8-0.5-0.5-0.3
Reaction time trials AUC0.30.51.4-0.6-0.6-0.8-0.6-0.6-1.2-0.6-0.6-0.6-0.7-0.61.1-0.8-0.6-0.6-0.2
Run reversals in cocaine runway, females0.60.61.2-0.9-0.9-0.7-0.9-0.8-0.7-0.9-0.8-0.8-0.7-0.80.5-0.6-0.8-0.7-1.1
Run reversals in cocaine runway, males0.80.81.5-1.0-1.0-0.8-1.0-1.0-1.2-0.9-1.0-1.0-0.6-0.91.2-0.6-0.8-0.90.1
Latency to leave start box in cocaine runway0.20.20.5-0.5-0.5-0.1-0.6-0.6-0.2-0.6-0.6-0.6-0.1-0.60.2-0.4-0.7-0.6-0.0
Latency to leave start box in cocaine runway, F0.10.10.40.20.20.60.10.10.60.10.00.10.50.0-0.40.1-0.1-0.10.5
Latency to leave start box in cocaine runway, M0.70.60.9-0.9-0.9-0.7-0.9-0.9-1.0-0.9-0.9-0.9-0.6-0.80.6-0.7-0.8-0.7-0.5
Std. dev. time between licks in bursts0.60.81.20.80.80.80.90.91.10.90.90.90.70.9-0.90.81.01.1-0.6
Total sessions with >9 infusions2.32.83.6-1.8-1.8-1.8-1.7-1.7-1.8-1.7-1.7-1.7-1.6-1.71.9-1.7-1.6-1.5-0.5
Short access day 1 total inactive lever presses4.45.86.6-2.6-2.6-2.5-2.5-2.5-2.4-2.5-2.5-2.5-2.4-2.52.2-2.5-2.5-2.2-1.6
Short access day 10 total inactive lever presses0.30.81.1-0.9-0.9-0.7-0.9-1.0-0.8-0.9-1.0-0.9-1.0-0.90.7-0.9-1.0-1.00.1
Short access day 1 total infusions2.93.94.4-2.0-2.0-2.0-2.1-2.1-1.9-2.0-2.1-2.1-2.0-2.01.9-2.1-2.0-2.1-0.2
Short access day 10 total infusions3.13.95.0-2.1-2.1-1.8-2.1-2.2-1.8-2.1-2.2-2.1-1.8-2.11.7-1.9-2.2-2.2-0.7
Short access total infusions1.92.52.9-1.7-1.7-1.6-1.7-1.7-1.5-1.7-1.7-1.7-1.4-1.71.6-1.5-1.7-1.7-0.1
Short access day 1 locomotion2.43.05.9-1.6-1.6-2.0-1.6-1.6-2.1-1.6-1.6-1.7-1.8-1.62.4-1.9-1.6-1.80.4
Short access day 10 total locomotion1.22.32.9-1.6-1.6-1.4-1.6-1.6-1.5-1.6-1.6-1.6-1.4-1.51.7-1.4-1.6-1.5-0.9
Short access total locomotion1.51.82.4-1.4-1.4-1.4-1.4-1.4-1.5-1.4-1.4-1.4-1.3-1.31.5-1.3-1.3-1.2-0.6
One hour access (0.3 mA shock)2.93.35.2-2.0-2.0-2.2-1.9-1.9-2.3-1.9-1.8-1.8-1.9-1.71.8-1.8-1.6-1.4-0.3
Compulsive drug intake2.32.74.61.51.51.61.61.61.51.61.61.71.71.7-2.11.61.72.00.4
One hour access (shock baseline)4.77.29.0-2.8-2.8-2.9-2.8-2.8-2.9-2.7-2.7-2.7-2.8-2.73.0-2.6-2.6-2.6-0.9
Social response proportion0.20.23.20.10.1-0.40.00.0-0.30.00.0-0.0-0.4-0.0-0.2-0.40.0-0.31.8
Social responses0.30.42.20.60.60.30.60.60.50.60.60.60.30.6-0.50.20.50.41.5
Social time0.00.10.2-0.0-0.0-0.3-0.1-0.1-0.4-0.1-0.1-0.1-0.3-0.1-0.3-0.2-0.1-0.20.5
Soleus weight3.19.110.2-3.2-3.2-3.2-3.1-3.1-3.1-3.1-3.1-3.0-3.1-3.02.9-3.1-2.9-2.6-2.7
Bone: stiffness0.10.10.80.20.20.30.20.20.90.20.20.20.20.2-0.30.20.20.3-0.6
Tibialis anterior weight1.03.54.5-2.0-2.0-2.1-1.9-1.9-1.8-1.9-1.9-1.8-2.1-1.81.9-2.0-1.7-1.5-1.4
Time to tail flick, vehicle, before self-admin0.20.21.2-0.1-0.1-0.6-0.0-0.1-0.3-0.1-0.1-0.1-0.5-0.11.1-0.3-0.2-0.40.6
Time to tail flick, vehicle, after self-admin4.76.28.22.72.72.52.62.62.12.62.62.62.22.6-1.92.42.42.22.9
Time to tail flick, test, before self-admin0.50.62.0-0.5-0.5-1.2-0.5-0.5-1.0-0.5-0.5-0.6-0.9-0.51.4-0.7-0.5-0.70.4
Time to tail flick, test, after self-admin1.41.51.9-1.3-1.3-1.3-1.3-1.3-0.9-1.3-1.3-1.3-1.3-1.31.1-1.3-1.4-1.3-0.1
Delta time to tail flick, vehicle, before/after SA2.62.53.51.51.51.91.51.51.61.51.51.61.71.5-1.81.61.61.60.7
Delta time to tail flick, test, before/after SA2.02.13.1-1.6-1.6-1.1-1.6-1.6-1.0-1.6-1.6-1.6-1.5-1.60.3-1.6-1.8-1.5-0.7
Tibia length0.82.24.51.41.41.41.51.40.91.51.41.51.51.5-0.71.61.61.42.1
Ambulatory time before self-admin0.10.10.5-0.3-0.3-0.2-0.3-0.3-0.2-0.3-0.3-0.3-0.6-0.30.7-0.2-0.3-0.3-0.6
Ambulatory time after self-admin0.20.30.50.40.40.70.40.50.70.40.50.50.70.5-0.70.60.50.70.2
Bone: tissue strength0.80.82.70.70.70.80.80.70.40.80.80.80.80.9-1.20.70.70.81.6
Total heroin consumption2.73.24.0-2.0-1.9-2.0-1.9-1.9-2.0-1.9-1.8-1.8-2.0-1.81.3-1.7-1.5-1.3-1.4
Bone: trabecular number2.54.16.7-2.1-2.1-2.2-2.1-2.1-2.6-2.0-2.1-2.0-2.0-2.02.1-2.0-1.9-1.90.5
Bone: trabecular spacing0.81.02.20.90.91.20.90.91.50.90.90.91.10.9-0.81.11.01.1-0.9
Bone: trabecular thickness0.40.51.1-0.5-0.5-0.8-0.5-0.5-0.9-0.6-0.6-0.6-0.8-0.60.6-0.8-0.7-1.01.0
Bone: trabecular tissue density0.10.20.8-0.4-0.4-0.3-0.4-0.4-0.1-0.4-0.4-0.4-0.3-0.50.3-0.3-0.3-0.5-0.9
Water consumed over 24 hours0.20.20.80.40.40.20.40.50.60.40.40.40.20.40.30.20.50.5-0.9
Number of responses in last shaping day1.51.62.2-1.3-1.3-1.4-1.3-1.3-1.3-1.3-1.3-1.3-1.5-1.30.7-1.4-1.3-1.4-0.3