Hub : Genes

Dnajb9

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Dnajb9 0.04 0.03 6.1e-04 0.04 0.03 0.02 0.03 1.5e-04 6.1e-04 9.5e-03 3.6e-04
2 PL gene expression Dnajb9 0.08 0.05 9.4e-05 0.03 0.03 0.04 0.03 3.1e-04 3.5e-04 2.2e-05 1.8e-04
3 Adipose isoform ratio NM_012699.3 0.2 0.08 5.6e-17 0.16 0.15 0.15 0.16 5.3e-17 5.6e-16 1.2e-16 2.2e-17
4 OFC gene expression Dnajb9 0.15 0.08 1.1e-03 0.06 0.11 0.11 0.08 1.4e-02 1.4e-03 1.6e-03 5.1e-03
5 Adipose alternative TSS XM_039111791.2 0.1 0.05 4.0e-08 0.07 0.07 0.06 0.06 1.3e-08 6.5e-08 3.6e-07 9.0e-08
6 Adipose alternative TSS NM_012699.3 0.1 0.05 3.4e-08 0.08 0.07 0.07 0.07 7.1e-09 4.8e-08 7.6e-08 8.0e-08
7 pVTA gene expression Dnajb9 0.16 0.09 1.7e-05 0.07 0.04 0.06 0.06 1.5e-06 1.7e-04 1.7e-05 1.6e-05
8 NAcc gene expression Dnajb9 0.09 0.05 1.7e-10 0.08 0.07 0.08 0.08 4.5e-12 1.5e-10 1.3e-11 1.4e-11
9 Adipose isoform ratio XM_039111791.2 0.21 0.09 1.7e-16 0.16 0.14 0.15 0.16 1.8e-17 8.2e-16 1.7e-16 3.5e-17
10 LHb gene expression Dnajb9 0.3 0.17 1.6e-03 0.03 0.1 0.04 0.05 8.0e-02 2.7e-03 3.9e-02 2.1e-02
11 BLA gene expression Dnajb9 0.11 0.06 3.7e-04 0.06 0.06 0.07 0.05 3.0e-04 3.9e-04 1.1e-04 1.3e-03
12 PL intron excision ratio chr6_66999373_67000105 0.03 0.02 3.4e-03 0.03 0.02 0.03 0.02 2.9e-04 4.1e-03 8.0e-04 2.9e-03
13 PL intron excision ratio chr6_67000331_67001884 0.03 0.02 2.8e-03 0.03 0.02 0.02 0.01 5.2e-04 3.4e-03 2.1e-03 9.5e-03
14 IC gene expression Dnajb9 0.1 0.07 5.6e-03 0.06 0.04 0.05 0.05 1.2e-03 6.4e-03 5.0e-03 3.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.71.12.80.60.4-1.30.81.7-1.71.21.31.30.61.00.2-0.20.8
Area under the delay curve0.30.31.4-0.5-0.30.30.3-0.50.5-0.4-0.4-0.40.41.20.7-0.7-0.7
BMI with tail0.51.64.8-1.7-0.60.8-1.8-0.50.5-0.4-0.4-0.4-1.7-1.4-2.22.2-0.5
BMI without tail0.41.35.2-0.20.70.0-0.6-0.10.1-0.2-0.4-0.3-1.7-1.5-2.32.3-0.9
Body weight0.52.15.21.22.3-1.81.31.7-1.71.61.61.6-0.0-0.3-1.41.4-0.3
Weight adjusted by age0.00.10.20.30.4-0.30.30.2-0.20.10.30.3-0.3-0.2-0.10.1-0.3
Bone surface1.32.34.31.30.6-1.91.72.1-2.11.71.61.61.31.80.7-0.70.7
Bone volume0.61.02.81.00.4-1.40.91.7-1.71.21.11.10.30.8-0.10.10.7
Breakpoint value in progressive ratio session2.42.94.71.81.9-2.11.72.2-2.22.12.02.11.10.90.4-0.41.4
Number of licking bursts0.20.30.6-0.2-0.40.40.1-0.70.7-0.7-0.7-0.60.30.40.5-0.5-0.2
Context. condit. distance diff. score0.50.62.90.51.7-0.80.61.2-1.20.50.30.40.50.2-0.10.10.5
Locomotion velocity, session 11.01.12.8-0.4-0.90.9-1.2-1.01.0-0.8-0.9-0.9-1.6-1.7-1.11.1-0.4
Locomotion distance, session 10.50.72.2-0.6-1.50.8-0.8-0.80.8-1.0-1.0-0.9-0.6-0.80.0-0.0-0.5
Locomotion velocity, session 20.60.72.6-0.5-1.61.0-0.6-0.80.8-1.0-1.1-1.10.0-0.30.3-0.3-0.5
Locomotion distance, session 20.30.51.9-0.4-1.40.7-0.7-0.80.8-0.9-0.9-0.9-0.3-0.30.3-0.3-0.1
Locomotion velocity, session 30.40.51.80.3-0.2-0.40.80.3-0.30.30.10.20.91.01.3-1.3-0.2
Locomotion distance, session 31.41.52.80.60.8-1.11.41.1-1.11.31.11.11.61.71.6-1.60.4
Stereotopy head waving bouts, day 31.41.62.1-0.9-0.91.5-1.1-1.41.4-1.4-1.4-1.5-1.4-1.4-1.01.0-1.2
Stereotopy head waving duration, day 30.40.50.8-0.2-0.80.9-0.6-0.90.9-0.7-0.7-0.8-0.7-0.8-0.20.2-0.4
Locomotion velocity, session 71.61.75.3-0.30.2-0.41.20.5-0.50.80.80.82.12.32.2-2.20.1
Locomotion distance, session 71.21.65.0-0.30.4-0.41.40.5-0.50.70.60.81.92.22.1-2.1-0.6
Stereotopy head waving bouts, day 70.10.10.6-0.2-0.50.2-0.1-0.10.1-0.2-0.4-0.4-0.1-0.80.0-0.0-0.4
Stereotopy head waving duration, day 70.30.41.3-0.6-1.10.6-0.7-0.60.6-0.4-0.4-0.5-0.3-1.0-0.00.0-0.3
Locomotion velocity, session 80.50.61.4-0.1-0.20.6-1.2-0.30.3-0.7-0.8-0.8-0.7-1.2-0.90.91.1
Locomotion distance, session 80.20.31.10.50.5-0.70.10.8-0.80.20.00.10.30.20.1-0.11.1
Degree of sensitization distance0.10.20.6-0.00.2-0.10.50.2-0.2-0.00.20.20.60.80.6-0.6-0.2
Degree of sensitization stereotypy0.10.10.30.4-0.2-0.50.20.6-0.60.30.20.10.3-0.50.2-0.20.3
Conditioned locomotion10.512.115.5-2.3-3.53.7-3.3-3.93.9-3.9-3.7-3.7-3.9-3.9-2.72.7-2.9
Cocaine response after cond. corrected0.50.61.50.10.5-0.70.60.7-0.70.80.70.80.91.01.2-1.20.3
Cocaine response after cond. not corrected0.70.81.8-0.10.4-0.80.60.9-0.90.90.80.91.11.31.2-1.20.5
Cocaine response before conditioning0.70.83.2-0.30.1-0.41.20.6-0.60.50.50.41.51.81.1-1.1-0.2
Saline control response0.40.61.60.91.3-0.71.20.6-0.60.70.50.50.50.90.3-0.3-0.6
Bone: connectivity density1.92.95.11.01.0-2.01.42.2-2.22.32.22.31.41.50.7-0.71.7
Bone: cortical apparent density0.50.71.3-1.1-0.00.9-1.1-0.70.7-0.7-0.6-0.6-0.9-1.0-0.90.9-0.3
Bone: cortical area1.01.53.41.91.0-1.81.11.6-1.61.11.31.20.60.60.2-0.21.2
Bone: cortical porosity0.10.10.2-0.2-0.3-0.1-0.3-0.40.4-0.20.00.1-0.30.3-0.30.30.0
Bone: cortical porosity0.10.10.60.50.3-0.60.40.1-0.10.10.30.40.10.70.1-0.10.0
Bone: cortical thickness0.30.40.90.40.6-0.9-0.10.7-0.70.40.70.6-0.3-0.3-0.90.91.0
Bone: cortical thickness0.70.81.9-0.6-0.20.8-1.3-0.60.6-0.9-0.8-0.8-1.4-1.3-1.11.10.2
Bone: cortical tissue density0.50.61.2-1.10.00.9-1.1-0.70.7-0.7-0.6-0.6-0.9-1.0-0.90.9-0.3
Condit. Reinf. active minus inactive responses3.43.86.62.61.8-2.22.42.0-2.01.71.82.01.82.01.8-1.81.3
Condit. Reinf. active-inactive response ratio2.42.64.21.81.6-1.62.01.5-1.51.51.61.71.51.91.6-1.60.7
Condit. Reinf. active responses4.85.912.53.52.4-3.02.72.6-2.62.32.42.51.91.91.6-1.62.3
Condit. Reinf. inactive responses0.81.03.51.90.9-1.30.61.1-1.10.70.70.70.1-0.4-0.30.31.6
Incentive salience index mean5.36.610.73.32.0-3.02.82.6-2.62.42.62.72.32.52.2-2.22.3
Condit. Reinf. lever presses4.26.07.72.61.3-2.82.42.4-2.42.42.62.72.52.72.2-2.22.4
Condit. Reinf. active minus inactive responses1.21.52.91.61.1-1.11.61.1-1.10.90.90.91.70.91.3-1.31.4
Condit. Reinf. active-inactive response ratio0.20.21.31.10.2-0.30.8-0.00.0-0.2-0.2-0.20.4-0.10.6-0.60.1
Condit. Reinf. active responses2.43.47.21.51.2-1.62.01.7-1.71.71.71.62.72.02.0-2.01.9
Condit. Reinf. inactive responses1.92.55.20.31.0-1.21.31.5-1.51.71.81.82.32.21.6-1.61.4
Condit. Reinf. lever presses1.11.52.51.31.2-1.21.41.4-1.41.61.31.31.41.10.6-0.61.2
Condit. Reinf. lever reinforcers received3.54.98.12.01.8-2.22.32.3-2.32.32.22.22.82.21.9-1.92.5
Conditioned reinforcement - actives1.52.53.81.91.6-1.91.91.6-1.61.81.71.71.31.21.3-1.31.1
Conditioned reinforcement - inactives1.52.36.82.62.1-1.91.91.5-1.51.21.31.40.70.30.9-0.90.8
Conditioned locomotion1.21.63.01.71.5-1.70.91.3-1.31.41.71.70.2-0.00.0-0.01.4
Patch foraging indifference point 0 sec2.64.88.02.82.2-2.42.72.2-2.22.42.12.02.32.61.3-1.31.4
Patch foraging indifference point AUC1.92.85.32.22.1-1.91.31.8-1.81.82.01.81.00.30.6-0.62.3
Delay disc. indifference point, 0s delay0.10.10.80.30.9-0.30.20.1-0.10.30.60.60.20.10.0-0.00.3
Delay disc. indifference point, 16s delay0.30.31.00.40.5-0.60.70.5-0.50.50.30.40.61.00.4-0.40.3
Delay disc. indifference point, 2s delay0.10.20.8-0.30.20.10.4-0.30.30.10.20.20.40.40.5-0.5-0.9
Delay disc. indifference point, 24s delay0.20.20.7-0.1-0.40.4-0.1-0.40.4-0.5-0.8-0.70.10.50.2-0.2-0.2
Delay disc. indifference point, 4s delay1.01.11.9-1.1-1.41.2-1.0-1.31.3-1.3-1.1-1.1-0.7-0.1-0.30.3-1.0
Delay disc. indifference point, 8s delay0.50.63.7-0.7-0.30.10.60.1-0.1-0.1-0.3-0.41.01.91.0-1.0-0.6
Indifference point function ln k0.20.41.9-1.3-0.70.5-0.1-0.50.5-0.3-0.6-0.5-0.00.80.2-0.2-1.4
Indifference point function log k0.20.41.9-1.3-0.70.5-0.1-0.50.5-0.3-0.6-0.5-0.00.80.2-0.2-1.4
Patch foraging total patch changes 0 sec2.34.47.82.82.2-2.42.62.1-2.12.42.12.02.02.30.9-0.91.3
Patch foraging total patch changes 12 sec1.41.85.72.41.6-1.61.51.4-1.41.21.21.10.90.90.5-0.51.4
Patch foraging total patch changes 18 sec1.11.63.11.41.4-1.31.71.0-1.01.21.41.31.71.50.8-0.80.4
Patch foraging total patch changes 24 sec1.32.35.22.31.3-1.61.81.5-1.51.41.51.41.71.31.2-1.21.3
Patch foraging total patch changes 6 sec3.75.69.73.12.4-2.62.22.6-2.62.82.62.42.01.91.2-1.22.7
Patch foraging time to switch 0 sec5.210.616.1-4.0-3.63.7-3.6-3.53.5-3.6-3.3-3.3-3.0-2.4-2.12.1-3.1
Patch foraging water rate 0 sec2.04.37.12.72.5-2.52.62.3-2.32.12.32.31.61.41.0-1.01.2
Patch foraging water rate 12 sec2.14.47.12.42.6-2.72.22.5-2.52.42.32.31.41.60.9-0.91.4
Patch foraging water rate 18 sec0.20.30.90.40.9-0.70.70.7-0.70.30.30.30.30.80.1-0.10.2
Patch foraging water rate 24 sec0.10.20.5-0.10.1-0.70.30.5-0.50.40.50.6-0.00.7-0.00.0-0.2
Patch foraging water rate 6 sec1.21.74.51.32.1-1.70.91.7-1.71.51.31.30.30.7-0.00.01.4
Seeking ratio, delayed vs. immediate footshock1.11.34.1-2.0-1.71.4-1.1-1.21.2-1.0-1.3-1.3-0.3-0.10.2-0.2-1.1
Distance traveled before self-admin0.60.82.51.10.3-0.41.60.2-0.20.10.20.21.10.51.6-1.6-0.5
Distance traveled after self-admin0.40.51.91.30.2-0.41.4-0.10.1-0.2-0.3-0.20.5-0.20.9-0.9-0.8
Extensor digitorum longus weight0.52.05.92.41.7-2.02.01.5-1.51.31.31.4-0.1-0.3-0.40.4-0.9
Bone: elastic displacement0.91.03.3-0.8-0.10.7-1.2-0.90.9-0.9-0.7-0.8-1.2-1.8-1.41.4-0.3
Bone: elastic work0.50.62.70.91.7-1.10.60.9-0.90.60.80.70.2-0.2-0.50.50.5
Bone: endosteal estimation0.61.43.41.80.5-1.01.80.8-0.80.50.40.41.11.41.7-1.7-0.5
Bone: endosteal perimeter1.73.67.22.70.9-2.02.51.7-1.71.41.31.32.02.02.5-2.50.7
Epididymis fat weight0.41.37.0-2.2-0.81.1-0.5-1.01.0-0.7-0.7-0.6-0.3-0.3-0.80.8-2.6
Delta time in closed arm before/after self-admin0.70.62.3-0.2-0.00.0-1.40.3-0.30.10.10.1-0.5-0.3-1.41.41.5
Delta time in open arm before/after self-admin0.60.61.8-0.1-0.40.6-0.2-0.80.8-0.8-0.6-0.6-1.0-1.3-0.80.8-1.2
Diff in mean of infusions in LGA sessions0.10.20.50.2-0.6-0.20.40.3-0.3-0.2-0.1-0.10.20.40.7-0.7-0.3
Delay discount exponential model param0.40.41.30.70.6-0.6-0.00.7-0.70.60.70.6-0.3-1.1-0.60.60.9
Extinction: sum of active levers before priming1.11.22.31.00.8-1.30.71.5-1.51.41.11.10.81.00.6-0.61.5
Active lever presses in extinction session 61.61.64.71.50.7-1.50.31.7-1.71.51.41.40.40.6-0.10.12.2
Bone: final force0.10.20.60.70.4-0.60.60.8-0.80.20.20.20.20.30.1-0.1-0.2
Bone: final moment0.10.20.70.80.4-0.60.60.8-0.80.30.20.20.10.30.1-0.1-0.1
Food consumed during 24 hour testing period0.60.81.60.30.30.7-0.1-1.11.1-1.0-1.2-1.2-0.7-1.1-0.70.7-1.3
Glucose1.21.84.80.72.2-1.0-0.31.6-1.60.90.80.9-0.5-0.7-1.91.92.0
Heart weight0.30.41.50.50.2-0.60.10.4-0.40.10.30.4-0.9-0.9-1.21.2-0.5
Delay discount hyperbolic model param0.40.51.60.70.7-0.6-0.10.7-0.70.60.60.5-0.4-1.3-0.80.80.9
Intermittent access intake day 1-15 change0.81.73.61.21.2-1.31.91.2-1.21.11.41.41.50.81.6-1.60.4
Intermittent access intake escalation0.71.43.01.21.0-1.11.71.0-1.00.91.21.21.40.71.5-1.50.4
Intermittent access intake escalation 22.63.06.11.81.4-1.52.51.4-1.41.31.41.32.21.62.3-2.30.6
Intermitt. access day 1 inactive lever presses0.10.41.30.3-0.1-0.1-0.70.3-0.30.10.50.4-0.7-0.8-1.11.11.1
Intermitt. access day 15 inactive lever presses0.00.10.4-0.30.20.1-0.40.3-0.3-0.1-0.2-0.0-0.00.1-0.10.10.6
Intermitt. access escalation Index1.31.93.0-1.5-1.21.6-1.3-1.71.7-1.4-1.4-1.4-1.1-0.7-1.01.0-1.7
Intermittent access day 1 total infusions0.71.22.7-0.8-1.10.9-1.6-1.01.0-0.9-0.9-0.8-1.6-1.1-1.21.2-0.2
Intermittent access day 15 total infusions0.10.10.50.3-0.20.1-0.1-0.30.3-0.2-0.0-0.0-0.6-0.7-0.20.2-0.1
Intermittent access terminal intake (last 3 days)0.20.21.00.60.4-0.2-0.20.0-0.00.10.20.2-0.8-1.0-0.60.60.2
Intermittent access total infusions0.70.82.80.3-0.10.2-1.0-0.50.5-0.4-0.3-0.3-1.7-1.6-1.41.40.2
Intermittent access day 1 locomotion0.10.10.50.2-0.3-0.0-0.6-0.10.1-0.1-0.0-0.1-0.7-0.4-0.50.50.5
Intermittent access day 15 total locomotion0.20.41.01.00.9-0.70.30.6-0.60.50.50.5-0.2-0.4-0.30.30.8
Intermittent access total locomotion0.50.51.31.00.8-0.8-0.10.7-0.70.60.50.4-0.6-0.8-0.80.81.1
Intermittent access standard deviation0.40.81.70.71.3-1.01.00.8-0.80.81.11.11.00.50.9-0.90.3
Left kidney weight0.52.35.01.92.2-1.91.81.8-1.81.51.81.80.90.40.3-0.30.6
Right kidney weight0.10.61.90.71.4-0.80.80.6-0.60.61.00.9-0.1-0.3-0.60.6-0.8
Cocaine induced anxiety0.71.03.0-0.30.00.11.2-0.30.3-0.2-0.3-0.31.61.51.7-1.7-1.1
Post-drug Anxiety0.60.71.70.70.4-0.51.00.3-0.30.40.50.41.31.31.3-1.30.3
Baseline Anxiety0.80.94.10.60.2-0.9-0.51.0-1.01.01.31.30.00.2-0.40.42.0
Tail length0.72.98.82.53.0-2.22.81.7-1.71.51.31.30.90.1-0.00.0-0.8
Length with tail2.18.919.83.84.4-3.84.23.4-3.43.13.13.02.21.20.7-0.70.6
Length without tail0.82.54.61.52.2-1.81.91.9-1.92.01.91.91.50.80.3-0.30.6
Times rat made contact with spout4.65.39.4-2.6-2.32.6-1.7-2.72.7-2.8-2.8-2.9-1.4-1.2-0.80.8-3.1
Lifetime Intake0.50.62.00.70.4-0.2-0.6-0.00.00.00.10.1-1.4-1.3-1.21.20.6
Liver weight, left0.40.72.2-1.1-0.10.4-1.0-0.40.4-0.1-0.1-0.1-1.0-0.7-1.51.5-0.7
Liver weight, right1.42.54.2-1.7-0.81.4-1.9-1.31.3-1.3-1.7-1.5-1.8-1.5-2.12.1-1.2
Locomotor activity12.419.427.24.14.9-5.14.55.2-5.25.24.94.94.23.52.6-2.63.7
Locomotor testing distance9.817.625.93.54.6-4.64.04.7-4.75.14.95.04.03.72.7-2.73.6
Locomotor testing rearing5.911.922.73.34.8-3.83.03.8-3.84.24.14.23.02.31.3-1.33.3
Locomotion in novel chamber0.30.30.8-0.2-0.70.5-0.4-0.60.6-0.5-0.7-0.6-0.8-0.9-0.10.1-0.6
Locomotion in novel chamber post-restriction0.20.31.20.1-1.00.10.1-0.10.1-0.2-0.2-0.20.70.01.1-1.10.5
Fecal boli incidents, locomotor time 11.62.45.61.92.4-1.92.21.4-1.41.71.71.81.10.10.9-0.90.1
Change in fecal boli incidents, locomotor task0.10.10.4-0.5-0.50.1-0.30.3-0.3-0.20.10.00.30.6-0.20.20.4
Time >=10cm from walls, locomotor time 11.51.62.1-1.4-0.91.2-1.2-1.41.4-1.2-1.0-1.1-1.3-1.2-1.51.5-1.3
Bouts of movement, locomotor time 11.41.64.90.8-0.10.7-0.8-1.21.2-1.1-1.1-1.0-2.0-2.2-1.51.5-0.8
Total resting periods, locomotor time 11.71.95.70.7-0.10.9-1.0-1.41.4-1.3-1.3-1.2-2.1-2.4-1.61.6-0.9
Rest time, locomotor task time 10.30.32.11.50.7-0.21.0-0.20.2-0.1-0.2-0.10.3-0.00.6-0.6-0.4
Distance moved, locomotor task time 10.20.31.1-1.1-0.90.3-0.80.1-0.1-0.3-0.0-0.0-0.20.6-0.50.50.3
Vertical activity count, locomotor time 10.10.20.4-0.50.1-0.3-0.10.5-0.50.10.50.60.10.2-0.60.60.0
Time >=10cm from walls, locomotor time 21.92.85.5-1.2-1.01.8-1.1-1.91.9-2.1-2.0-2.0-1.5-1.2-1.21.2-2.4
Bouts of movement, locomotor time 20.50.72.2-1.5-1.20.9-0.4-1.11.1-0.7-0.8-0.60.10.50.4-0.4-1.0
Total resting periods, locomotor time 20.61.02.9-1.7-1.41.2-0.7-1.31.3-0.9-1.0-0.8-0.20.30.2-0.2-1.2
Rest time, locomotor task time 20.30.40.90.0-0.10.6-0.3-0.80.8-0.7-0.5-0.4-0.9-0.7-0.50.5-1.0
Distance moved, locomotor task time 20.00.00.2-0.1-0.20.10.00.2-0.2-0.0-0.2-0.30.20.50.3-0.30.2
Vertical activity count, locomotor time 20.20.21.2-0.9-0.20.40.2-0.40.4-0.3-0.4-0.40.30.30.3-0.3-1.1
Light reinforcement 10.41.02.9-0.20.80.51.0-0.70.7-0.2-0.5-0.41.11.41.4-1.4-1.7
Light reinforcement 20.81.22.1-0.6-0.91.4-0.4-1.41.4-1.2-1.4-1.40.30.61.2-1.2-0.8
Bone: marrow area0.81.74.01.90.7-1.22.01.0-1.00.70.60.61.31.51.9-1.9-0.4
Bone: maximum diameter3.26.013.73.71.7-3.13.02.6-2.62.12.22.22.12.12.2-2.21.7
Bone: maximum force0.50.81.91.21.0-1.21.21.4-1.40.80.70.60.50.70.3-0.3-0.0
Bone: maximum moment0.50.81.91.20.9-1.31.11.4-1.40.80.70.60.40.60.2-0.20.0
Mean time between licks in bursts0.20.62.60.40.50.3-0.5-0.40.4-0.5-0.4-0.4-1.6-1.4-1.11.1-0.1
Mean num. licks in bursts0.71.03.1-1.3-0.81.0-0.8-0.80.8-0.9-0.9-1.0-1.0-0.9-1.01.0-1.8
Cd content in liver0.10.10.5-0.70.00.4-0.20.2-0.20.40.30.30.1-0.1-0.20.2-0.2
Co content in liver5.05.88.42.72.9-2.82.72.5-2.52.72.62.62.31.71.8-1.81.6
Cu content in liver0.30.40.9-0.9-0.60.7-0.5-1.01.0-0.5-0.6-0.60.1-0.30.3-0.3-0.5
Fe content in liver1.21.54.51.10.8-0.81.70.6-0.60.60.60.52.11.31.9-1.90.1
K content in liver0.70.72.3-0.3-0.5-0.00.20.0-0.00.40.40.31.31.51.5-1.51.0
Mg content in liver0.40.51.60.10.2-0.10.40.1-0.10.40.30.30.91.11.3-1.30.7
Mn content in liver1.51.73.2-0.7-0.81.30.3-1.71.7-1.2-1.0-1.10.70.51.8-1.8-1.8
Na content in liver0.50.52.4-1.1-1.60.4-0.1-0.20.20.20.0-0.00.80.31.1-1.1-0.0
Rb content in liver1.41.72.9-0.9-0.91.6-1.0-1.71.7-1.6-1.6-1.6-0.9-1.2-0.50.5-1.4
Se content in liver1.01.24.8-0.2-1.00.30.6-0.30.3-0.4-0.3-0.41.81.22.2-2.2-0.1
Sr content in liver0.10.00.2-0.5-0.20.2-0.3-0.10.10.30.10.1-0.1-0.0-0.30.3-0.1
Zn content in liver0.40.51.40.60.2-0.50.70.3-0.30.40.30.31.20.71.1-1.10.7
Bone: minimum diameter1.22.33.61.80.8-1.91.81.5-1.51.31.31.31.61.81.6-1.60.9
Time in familiar zone, hab. session 10.10.10.60.50.8-0.10.30.2-0.20.30.10.2-0.30.1-0.30.30.1
Time in novel zone, hab. session 10.10.10.3-0.6-0.40.1-0.40.1-0.10.20.30.20.4-0.10.4-0.40.4
Total zone transitions, hab. session 10.91.34.0-1.5-2.01.3-1.1-1.31.3-1.2-1.3-1.3-0.30.10.3-0.3-0.7
Total locomotion distance, hab. session 10.71.13.7-1.2-1.91.1-0.5-0.90.9-1.2-1.2-1.20.20.40.6-0.6-1.1
Locomotion velocity, hab. session 10.81.24.8-0.8-2.20.9-0.5-1.01.0-1.5-1.5-1.5-0.00.10.4-0.4-1.1
Time in familiar zone, hab. session 21.01.12.0-1.3-0.30.9-1.2-0.90.9-0.7-0.7-0.7-1.4-0.8-1.41.4-0.9
Time in novel zone, hab. session 21.21.23.01.71.0-1.11.31.1-1.10.90.80.81.20.41.1-1.11.0
Total zone transitions, hab. session 20.20.20.8-0.5-0.90.3-0.3-0.30.3-0.5-0.4-0.40.40.40.5-0.50.4
Total locomotion distance, hab. session 20.60.72.5-0.6-1.60.8-0.4-0.80.8-1.3-1.2-1.20.1-0.00.4-0.4-0.6
Locomotion velocity, hab. session 20.60.82.8-0.7-1.70.8-0.6-0.80.8-1.4-1.3-1.2-0.1-0.10.3-0.3-0.6
Novel to familiar place preference ratio0.40.41.9-0.3-1.40.4-0.1-0.20.2-0.8-0.6-0.70.40.21.1-1.1-0.1
Novelty place preference0.40.41.4-0.0-1.10.30.1-0.00.0-0.7-0.6-0.70.60.31.2-1.20.0
Time in novel zone, NPP test0.40.41.3-0.0-0.90.20.2-0.00.0-0.7-0.6-0.70.60.41.2-1.2-0.1
Total zone transitions, NPP test0.40.61.8-0.0-1.0-0.10.20.2-0.20.10.20.30.91.31.3-1.30.8
Total locomotion distance, NPP test0.40.61.8-0.4-1.30.40.0-0.40.4-0.8-0.6-0.60.60.91.1-1.1-0.4
Locomotion velocity, NPP test0.30.51.5-0.2-1.20.20.1-0.10.1-0.5-0.4-0.30.71.01.2-1.20.1
Intraocular pressure0.40.61.2-0.40.80.6-0.5-0.90.9-1.0-0.7-0.8-1.1-0.5-0.70.7-1.1
Delta distance traveled before/after self-admin0.10.10.5-0.2-0.70.10.2-0.40.4-0.2-0.3-0.30.10.20.5-0.5-0.4
Delta ambulatory time before/after self-admin0.30.31.2-0.2-0.70.30.3-0.70.7-0.6-0.5-0.50.00.10.6-0.6-1.1
Parametrial fat weight0.51.12.51.41.6-1.30.91.0-1.01.51.21.2-0.40.2-0.70.70.2
Pavlov. Cond. lever latency1.31.63.0-1.1-0.11.2-1.0-1.01.0-1.1-1.3-1.3-1.7-1.7-1.41.4-1.5
Pavlov. Cond. magazine entry latency1.31.75.8-1.7-2.41.5-1.1-1.71.7-1.4-1.2-1.2-0.40.50.2-0.2-1.0
Pavlov. Cond. change in total contacts0.40.41.1-0.1-1.10.00.4-0.10.1-0.00.30.30.81.01.0-1.0-0.1
Pavlov. Cond. index score0.40.52.2-0.3-1.50.20.1-0.40.4-0.3-0.0-0.00.81.31.1-1.10.1
Pavlov. Cond. latency score0.30.41.5-0.1-1.1-0.00.2-0.20.2-0.10.10.20.91.21.0-1.00.4
Pavlov. Cond. lever contacts1.72.05.10.8-0.2-1.21.31.0-1.01.21.41.42.02.31.8-1.81.1
Pavlov. Cond. magazine entry number1.01.24.71.42.2-1.31.01.4-1.41.21.01.00.3-0.4-0.20.20.4
Pavlov. Cond. intertrial magazine entries1.11.44.52.12.0-1.31.61.2-1.20.81.01.00.50.30.2-0.20.1
Pavlov. Cond. lever-magazine prob. diff.0.50.62.3-0.4-1.50.30.1-0.50.5-0.4-0.0-0.00.71.21.2-1.2-0.1
Pavlov. Cond. response bias0.40.53.0-0.8-1.70.6-0.4-0.80.8-0.5-0.3-0.30.31.00.6-0.6-0.0
Pavlov. Cond. lever latency1.31.75.7-1.6-2.41.4-0.8-1.61.6-1.4-1.3-1.3-0.00.30.9-0.9-1.3
Pavlov. Cond. magazine entry latency0.10.10.4-0.5-0.00.5-0.6-0.30.3-0.2-0.3-0.4-0.3-0.4-0.40.4-0.2
Pavlov. Cond. change in total contacts0.71.15.41.32.3-0.90.51.1-1.11.00.90.90.1-0.3-0.90.90.8
Pavlov. Cond. index score0.40.52.30.81.5-0.50.10.7-0.70.60.50.4-0.3-0.5-0.80.80.6
Pavlov. Cond. latency score0.20.31.50.61.2-0.20.10.5-0.50.40.30.2-0.2-0.4-0.60.60.4
Pavlov. Cond. lever contacts0.81.04.11.12.0-0.90.51.1-1.11.00.90.9-0.2-0.4-1.01.00.8
Pavlov. Cond. magazine entry number0.30.41.1-0.2-1.10.10.4-0.50.5-0.6-0.4-0.30.50.61.0-1.0-0.7
Pavlov. Cond. intertrial magazine entries1.32.04.41.30.4-1.21.90.9-0.90.80.80.82.12.02.1-2.10.7
Pavlov. Cond. lever-magazine prob. diff.0.40.52.40.81.5-0.40.10.6-0.60.50.30.3-0.3-0.6-0.90.90.4
Pavlov. Cond. response bias1.21.75.61.32.4-1.30.61.6-1.61.51.41.40.0-0.2-0.90.91.3
Time in closed arm before self-admin1.51.97.5-0.5-0.70.41.5-0.60.6-0.3-0.5-0.61.51.52.7-2.7-1.7
Time in closed arm after self-admin0.70.82.7-0.4-0.8-0.10.30.3-0.30.30.20.11.21.71.6-1.60.4
Time in open arm before self-admin0.50.62.2-0.20.3-0.2-1.00.4-0.40.30.30.2-0.7-0.3-1.51.51.1
Time in open arm after self-admin1.01.13.2-0.2-0.30.7-1.0-0.80.8-0.8-0.6-0.6-1.6-1.8-1.51.5-0.5
Bone: periosteal estimation1.02.15.72.40.9-1.92.01.5-1.51.01.11.01.11.41.4-1.40.5
Bone: periosteal perimeter1.83.15.32.21.0-2.02.31.7-1.71.41.41.31.91.92.1-2.10.8
Bone: post-yield work2.63.87.31.81.4-2.12.72.0-2.01.91.81.82.02.52.0-2.00.1
Progressive ratio test 1 active lever presses1.01.33.81.91.8-1.40.91.2-1.21.21.21.1-0.3-0.2-0.20.20.9
Progressive ratio test 1 breakpoint0.91.13.71.91.7-1.30.91.1-1.11.21.01.0-0.3-0.2-0.20.20.9
Progressive ratio test 1 inactive lever presses0.91.33.21.81.2-1.51.01.3-1.31.11.41.40.4-0.10.3-0.31.4
Progressive ratio test 2 active lever presses0.20.30.5-0.3-0.70.4-0.6-0.50.5-0.6-0.6-0.6-0.7-0.6-0.40.4-0.2
Progressive ratio test 2 breakpoint0.20.30.6-0.3-0.70.4-0.7-0.50.5-0.6-0.6-0.6-0.8-0.6-0.50.5-0.1
Progressive ratio test 2 inactive lever presses0.10.20.6-0.3-0.80.4-0.3-0.40.4-0.7-0.4-0.4-0.2-0.20.1-0.1-0.4
Incentive Sensitization - Responses0.70.93.0-1.4-1.71.1-0.9-1.01.0-1.1-1.0-0.90.00.30.3-0.3-0.7
Incentive Sensitization - Breakpoint0.70.92.9-1.5-1.71.1-0.9-1.01.0-1.1-0.9-0.9-0.00.20.2-0.2-0.7
Sum of active levers in priming session hrs 5-60.30.30.60.70.8-0.70.40.7-0.70.50.40.40.0-0.0-0.20.20.2
Progressive ratio0.50.81.5-0.6-0.40.9-1.1-0.90.9-0.9-0.9-0.9-1.0-1.2-0.90.9-0.5
Food seeking constrained by brief footshock1.11.42.9-1.3-1.01.4-0.5-1.41.4-1.4-1.4-1.6-0.3-0.40.1-0.1-1.7
Seeking ratio, punishment vs. effort0.20.30.8-0.6-0.30.30.4-0.20.2-0.2-0.3-0.40.60.80.9-0.9-0.5
Retroperitoneal fat weight0.10.51.6-1.2-0.60.1-0.80.1-0.10.30.30.3-0.6-0.2-1.31.3-0.5
Reaction time number correct1.01.93.90.91.4-1.51.01.7-1.71.72.01.91.00.9-0.30.31.2
Reaction time mean minus median0.20.41.6-0.6-1.30.5-0.2-0.40.4-0.30.10.10.50.61.1-1.1-0.1
Reaction time mean minus median AUC0.10.30.90.30.0-0.20.50.3-0.30.20.60.60.90.81.0-1.00.3
Reaction time num false alarms3.04.29.52.02.0-1.62.71.3-1.31.41.41.32.82.43.1-3.10.6
Reaction time num false alarms AUC1.82.88.31.31.3-0.92.10.8-0.80.90.90.82.52.12.9-2.90.2
Reaction time trials correct on left1.01.93.90.91.4-1.51.01.7-1.71.72.01.91.00.9-0.30.31.2
Reaction time trials on left1.01.94.00.91.4-1.51.11.7-1.71.72.01.91.01.0-0.20.21.2
Reaction time mean0.60.92.8-1.7-1.21.3-0.7-1.21.2-0.9-0.7-0.60.20.50.5-0.5-1.0
Reaction time mean AUC0.50.82.3-1.5-1.21.2-0.6-1.01.0-0.9-0.6-0.60.20.50.4-0.4-0.9
Median of all reaction times0.71.02.9-1.7-1.01.4-0.8-1.31.3-1.0-0.9-0.8-0.10.20.2-0.2-1.2
Reaction time omissions0.20.30.8-0.1-0.60.50.4-0.50.5-0.5-0.3-0.40.50.20.9-0.9-0.7
Reaction time false alarm rate1.52.08.31.10.9-0.51.70.3-0.30.40.20.21.91.62.9-2.9-0.1
Reaction time premature initiation rate0.30.52.10.91.4-0.5-0.10.3-0.30.30.50.5-0.40.1-0.90.90.9
Reaction time premature initiations0.71.33.71.51.9-1.20.51.0-1.01.11.41.40.00.6-0.80.81.3
Std. dev. reaction times0.61.03.2-1.6-1.81.4-1.1-1.31.3-0.9-0.5-0.5-0.10.10.5-0.5-0.5
Reaction time trials completed1.01.94.00.91.4-1.51.11.7-1.71.72.01.91.01.0-0.20.21.2
Reaction time trials AUC0.91.84.01.01.4-1.51.01.7-1.71.72.01.90.90.9-0.30.31.0
Run reversals in cocaine runway, females6.06.08.2-2.2-2.32.7-2.5-2.82.8-2.9-2.6-2.7-2.7-2.4-1.71.7-1.9
Run reversals in cocaine runway, males0.30.31.00.50.5-0.5-0.10.6-0.60.50.50.5-0.1-0.8-0.20.21.0
Latency to leave start box in cocaine runway0.60.64.2-2.0-1.00.8-1.4-0.40.4-0.2-0.3-0.3-0.30.2-0.50.50.2
Latency to leave start box in cocaine runway, F0.50.63.8-1.9-0.70.2-0.40.1-0.10.40.60.50.91.20.3-0.3-0.0
Latency to leave start box in cocaine runway, M1.00.92.6-0.8-0.50.8-1.6-0.60.6-0.5-1.0-0.9-1.4-0.9-1.21.20.5
Std. dev. time between licks in bursts0.10.10.50.30.30.30.2-0.20.2-0.4-0.7-0.6-0.1-0.20.4-0.40.2
Total sessions with >9 infusions0.30.40.80.90.7-0.80.20.7-0.70.70.80.8-0.4-0.0-0.20.20.8
Short access day 1 total inactive lever presses1.52.05.41.91.4-1.60.51.8-1.81.61.41.50.2-0.1-0.40.42.3
Short access day 10 total inactive lever presses0.30.82.40.60.0-0.51.10.8-0.80.20.20.21.41.21.5-1.50.6
Short access day 1 total infusions0.81.02.41.31.5-1.30.51.1-1.11.11.21.2-0.4-0.1-0.60.60.9
Short access day 10 total infusions0.81.02.01.31.0-0.8-0.40.6-0.60.70.50.6-1.2-1.2-1.41.41.4
Short access total infusions0.70.81.91.41.2-1.20.30.9-0.91.00.91.0-0.5-0.4-0.60.61.2
Short access day 1 locomotion1.11.33.01.20.9-1.50.61.5-1.51.21.31.30.50.60.3-0.31.7
Short access day 10 total locomotion0.10.21.51.20.4-0.60.40.4-0.40.10.30.3-0.2-0.20.0-0.00.4
Short access total locomotion0.40.51.41.20.8-1.00.60.8-0.80.70.80.70.20.30.3-0.30.9
One hour access (0.3 mA shock)0.20.21.00.40.50.10.3-0.50.5-0.4-0.5-0.5-0.6-0.4-0.10.1-1.0
Compulsive drug intake1.82.15.1-0.4-0.21.1-1.6-1.31.3-1.1-1.2-1.2-2.3-2.0-2.12.1-0.8
One hour access (shock baseline)0.00.00.10.10.0-0.20.40.1-0.1-0.00.10.10.20.20.3-0.3-0.1
Social response proportion2.02.34.7-1.70.41.2-1.4-1.31.3-1.2-1.1-1.1-1.9-1.4-2.22.2-1.8
Social responses0.50.71.70.31.2-0.61.30.6-0.60.90.80.90.90.70.9-0.9-0.4
Social time1.21.63.6-0.41.00.7-0.5-1.01.0-1.3-1.3-1.2-1.5-1.5-1.71.7-1.9
Soleus weight0.61.86.52.41.1-0.50.3-0.10.10.00.10.1-2.0-2.6-1.71.7-0.9
Bone: stiffness0.10.10.40.70.2-0.50.10.5-0.50.1-0.0-0.1-0.3-0.1-0.20.20.0
Tibialis anterior weight2.06.912.73.23.1-3.63.23.2-3.23.13.23.21.51.10.7-0.70.6
Time to tail flick, vehicle, before self-admin0.50.50.90.8-0.0-0.70.80.7-0.70.60.50.40.81.01.0-1.00.6
Time to tail flick, vehicle, after self-admin0.10.10.8-0.3-0.6-0.1-0.00.3-0.30.20.30.20.20.9-0.10.10.4
Time to tail flick, test, before self-admin0.20.20.5-0.30.10.60.2-0.50.5-0.3-0.7-0.60.30.50.6-0.6-0.6
Time to tail flick, test, after self-admin0.60.61.9-0.60.80.4-0.7-0.50.5-0.2-0.5-0.3-1.2-1.1-1.41.4-0.5
Delta time to tail flick, vehicle, before/after SA0.50.51.2-1.1-1.00.8-1.1-0.50.5-0.6-0.4-0.5-0.8-0.1-0.80.8-0.1
Delta time to tail flick, test, before/after SA1.71.84.0-1.4-0.31.0-1.6-1.01.0-1.0-0.9-0.9-1.8-1.7-2.02.0-0.8
Tibia length0.41.24.71.52.2-1.21.01.4-1.40.90.70.70.70.0-0.20.21.2
Ambulatory time before self-admin0.60.92.20.80.2-0.71.40.8-0.80.50.70.71.31.01.5-1.50.1
Ambulatory time after self-admin0.50.62.31.10.1-0.51.50.2-0.20.10.30.20.90.51.2-1.2-0.5
Bone: tissue strength0.20.20.8-0.20.9-0.30.30.5-0.50.50.40.30.10.1-0.60.6-0.4
Total heroin consumption0.20.30.70.20.7-0.50.10.6-0.60.80.50.60.20.40.1-0.10.8
Bone: trabecular number0.50.81.90.30.2-1.10.31.4-1.41.21.21.30.20.5-0.30.31.2
Bone: trabecular spacing1.52.13.5-1.4-0.81.9-1.3-1.71.7-1.6-1.9-1.9-1.0-1.2-0.70.7-1.4
Bone: trabecular thickness0.30.40.80.80.6-0.70.00.8-0.80.50.70.7-0.5-0.6-0.60.60.9
Bone: trabecular tissue density1.52.23.9-0.9-1.01.6-1.3-1.41.4-2.0-1.9-2.0-1.3-1.8-1.21.2-1.3
Water consumed over 24 hours0.20.31.0-1.0-0.10.6-0.5-0.50.5-0.5-0.5-0.5-0.3-0.4-0.60.6-0.8
Number of responses in last shaping day1.11.22.00.8-0.3-1.10.60.9-0.91.21.31.21.11.41.3-1.31.3