Dnah17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC mRNA stability Dnah17 0.16 0.11 3.0e-03 0.05 0.04 0.05 0.03 3.0e-02 4.2e-02 2.8e-02 6.2e-02
2 Adipose gene expression Dnah17 0.22 0.12 0.0e+00 0.17 0.17 0.16 0.16 3.4e-18 2.3e-18 2.5e-17 8.7e-18
3 LHb gene expression Dnah17 0.11 0.08 9.6e-03 0.08 0.08 0.07 0.08 5.4e-03 6.6e-03 7.5e-03 5.9e-03
4 PL mRNA stability Dnah17 0.21 0.11 2.2e-16 0.15 0.15 0.14 0.15 3.2e-16 3.2e-16 1.2e-15 4.7e-16
5 OFC gene expression Dnah17 0.34 0.17 1.1e-05 0.12 0.12 0.13 0.12 9.4e-04 1.1e-03 5.3e-04 9.4e-04
6 PL gene expression Dnah17 0.52 0.15 0.0e+00 0.32 0.32 0.32 0.32 1.4e-36 3.0e-36 1.4e-35 1.2e-36
7 Adipose mRNA stability Dnah17 0.03 0.03 1.2e-03 0.01 0.01 0.02 0.01 4.5e-02 8.0e-03 2.4e-03 2.1e-02
8 BLA mRNA stability Dnah17 0.38 0.14 5.6e-12 0.19 0.2 0.2 0.19 1.7e-10 8.9e-11 9.3e-11 2.0e-10
9 IL gene expression Dnah17 0.34 0.15 6.3e-08 0.18 0.18 0.14 0.16 4.9e-05 4.1e-05 3.6e-04 9.6e-05
10 BLA gene expression Dnah17 0.5 0.13 0.0e+00 0.34 0.34 0.34 0.34 1.1e-18 4.1e-19 9.3e-19 4.7e-19
11 NAcc mRNA stability Dnah17 0.05 0.03 2.9e-07 0.06 0.05 0.04 0.04 2.4e-07 2.4e-06 1.2e-05 8.8e-06
12 pVTA mRNA stability Dnah17 0.2 0.14 3.4e-03 0.04 0.03 0.01 0.03 5.8e-03 2.4e-02 7.5e-02 1.7e-02
13 IL mRNA stability Dnah17 0.3 0.15 1.0e-06 0.17 0.21 0.22 0.18 6.1e-05 9.4e-06 4.9e-06 3.6e-05
14 Liver gene expression Dnah17 0.09 0.06 2.6e-04 0.02 0.02 0.03 0.02 6.6e-03 3.4e-03 3.8e-04 1.1e-03
15 LHb mRNA stability Dnah17 0.41 0.18 1.7e-06 0.13 0.21 0.13 0.15 6.5e-04 9.8e-06 6.6e-04 2.1e-04
16 RMTg gene expression Dnah17 0.39 0.2 1.5e-03 0.06 0.07 0.05 0.07 8.5e-03 5.4e-03 2.3e-02 5.9e-03
17 Brain mRNA stability Dnah17 0.46 0.16 0.0e+00 0.21 0.26 0.26 0.25 4.1e-19 1.6e-24 1.9e-24 6.1e-23
18 pVTA gene expression Dnah17 0.65 0.14 0.0e+00 0.31 0.33 0.32 0.3 8.6e-14 9.9e-15 1.6e-14 2.6e-13
19 Brain gene expression Dnah17 0.59 0.15 0.0e+00 0.05 0.2 0.17 0.18 2.2e-05 3.8e-18 7.1e-16 6.0e-17
20 NAcc gene expression Dnah17 0.23 0.11 2.1e-05 0.03 0.05 0.06 0.02 5.9e-04 2.9e-06 8.6e-08 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.81.43.91.4-1.1-1.4-0.91.8-1.6-1.0-0.7-0.9-1.0-1.3-1.30.9-1.00.72.00.91.3-0.4-0.6
Area under the delay curve1.41.53.7-1.31.11.91.0-0.81.0-0.10.61.60.61.61.6-1.7-0.6-1.7-1.1-1.5-1.6-0.70.5
BMI with tail0.82.69.6-1.10.1-0.80.3-1.00.72.20.9-1.71.3-1.3-1.31.41.62.60.42.22.03.1-2.1
BMI without tail1.02.14.11.4-1.2-1.8-1.01.0-0.8-1.1-0.7-1.7-0.5-1.9-2.01.71.41.71.62.01.91.2-1.3
Body weight0.52.15.3-1.41.61.41.6-2.32.12.21.80.42.20.90.9-0.20.80.4-1.10.2-0.12.2-0.8
Weight adjusted by age0.10.10.5-0.30.20.30.30.00.1-0.10.40.20.3-0.1-0.1-0.1-0.7-0.20.60.00.20.2-0.6
Bone surface0.91.610.4-0.71.10.71.30.00.5-0.51.31.70.81.01.0-1.5-3.2-1.91.1-1.0-0.5-0.50.4
Bone volume0.40.66.10.10.3-0.00.50.7-0.3-0.70.60.60.20.10.2-0.6-2.5-0.81.8-0.10.4-0.2-0.4
Breakpoint value in progressive ratio session1.21.34.2-0.30.6-0.51.0-0.50.70.51.4-0.11.3-0.8-0.90.5-1.70.42.01.31.42.0-1.7
Number of licking bursts0.10.10.50.20.10.40.1-0.20.2-0.50.00.20.10.40.3-0.30.7-0.2-0.3-0.2-0.3-0.10.2
Context. condit. distance diff. score0.30.31.8-0.80.6-0.00.8-0.40.60.40.80.60.80.00.1-0.5-1.3-0.50.5-0.10.10.50.0
Locomotion velocity, session 11.01.03.7-0.50.51.40.2-0.50.30.2-0.20.9-0.11.41.3-1.00.7-0.9-1.9-1.5-1.6-1.21.2
Locomotion distance, session 12.32.96.72.6-2.1-1.2-2.11.7-1.9-1.5-2.0-2.0-1.8-1.5-1.52.12.21.80.61.41.2-0.4-0.9
Locomotion velocity, session 20.50.61.50.8-1.0-0.6-1.11.0-1.2-0.4-1.0-0.9-1.0-0.5-0.50.80.70.80.30.50.5-0.5-0.4
Locomotion distance, session 24.86.710.63.2-3.2-2.3-3.22.9-3.3-2.0-2.9-3.1-2.9-2.4-2.53.02.72.81.42.12.1-0.8-1.4
Locomotion velocity, session 30.60.72.1-0.1-0.10.8-0.3-0.0-0.1-0.5-0.70.5-0.60.90.9-0.80.9-0.8-1.4-1.1-1.3-1.31.2
Locomotion distance, session 30.40.42.40.6-0.5-0.5-0.60.1-0.20.2-0.6-0.9-0.3-0.6-0.60.91.61.0-0.50.60.30.4-0.1
Stereotopy head waving bouts, day 31.72.03.9-1.91.71.41.9-1.61.61.61.91.31.81.11.2-1.4-2.0-1.0-0.2-0.7-0.50.9-0.2
Stereotopy head waving duration, day 31.92.26.3-2.11.81.52.0-1.41.51.42.01.61.81.21.2-1.6-2.5-1.30.1-0.9-0.60.7-0.2
Locomotion velocity, session 70.20.20.80.5-0.2-0.2-0.30.4-0.2-0.9-0.40.3-0.5-0.1-0.2-0.2-0.1-0.60.0-0.3-0.4-0.70.7
Locomotion distance, session 72.43.05.42.3-1.9-2.2-1.72.1-1.8-1.7-1.5-1.7-1.5-2.1-2.01.90.61.42.01.71.80.0-0.9
Stereotopy head waving bouts, day 73.33.77.0-2.72.41.92.4-2.22.31.72.32.12.21.71.8-2.2-2.1-1.8-0.9-1.4-1.30.80.5
Stereotopy head waving duration, day 75.06.19.2-3.02.92.82.9-2.52.62.02.62.92.42.72.8-2.8-2.7-2.6-1.5-2.3-2.10.21.0
Locomotion velocity, session 80.80.92.3-1.00.70.70.7-0.20.4-0.10.51.30.30.80.9-1.5-1.4-1.5-0.4-1.3-1.1-0.91.1
Locomotion distance, session 82.23.24.62.0-2.0-2.1-1.81.9-2.0-1.4-1.5-2.0-1.5-2.1-2.12.10.91.81.91.91.90.1-1.2
Degree of sensitization distance2.42.45.51.9-1.7-1.8-1.52.3-2.0-2.3-1.4-1.0-1.6-1.5-1.51.1-0.50.52.31.11.3-0.8-0.6
Degree of sensitization stereotypy1.41.62.8-1.71.51.21.6-1.41.61.01.41.41.41.21.2-1.5-1.3-1.2-0.7-0.9-1.00.50.5
Conditioned locomotion0.20.20.90.9-0.4-0.4-0.30.4-0.3-0.7-0.2-0.5-0.2-0.3-0.30.40.30.40.70.60.60.2-0.5
Cocaine response after cond. corrected0.20.30.9-0.90.60.30.7-0.80.60.60.80.20.80.30.2-0.2-0.30.00.10.10.10.7-0.4
Cocaine response after cond. not corrected0.10.10.4-0.70.30.30.3-0.40.30.10.30.40.30.40.3-0.4-0.3-0.4-0.1-0.3-0.2-0.00.1
Cocaine response before conditioning0.50.62.80.6-0.50.0-0.61.0-0.7-1.2-0.90.5-1.00.20.2-0.5-0.3-0.9-0.2-0.9-0.8-1.71.2
Saline control response1.92.48.80.6-0.60.3-1.00.8-0.7-2.0-1.61.0-1.60.91.0-1.21.4-1.6-1.8-2.0-2.2-3.02.7
Bone: connectivity density1.01.64.41.7-1.3-1.7-1.32.1-1.8-1.7-1.2-0.6-1.6-1.2-1.20.7-0.70.11.40.30.6-1.30.4
Bone: cortical apparent density1.62.15.21.3-1.4-1.6-1.41.2-1.50.3-0.9-2.1-0.9-1.5-1.62.21.42.30.81.61.70.6-1.3
Bone: cortical area2.23.310.2-2.62.22.12.1-2.32.13.22.30.92.41.71.8-1.2-0.8-0.1-1.2-0.6-0.41.6-0.6
Bone: cortical porosity1.82.03.5-1.91.51.71.5-1.21.21.21.21.61.11.71.6-1.8-1.7-1.5-1.0-1.5-1.3-0.20.7
Bone: cortical porosity2.62.85.1-2.31.92.01.9-1.41.61.31.61.91.51.91.8-2.1-2.0-1.8-1.0-1.6-1.5-0.00.7
Bone: cortical thickness1.01.68.9-1.20.20.5-0.1-1.10.43.00.3-1.30.70.30.40.82.62.2-1.90.50.41.3-0.8
Bone: cortical thickness0.60.73.2-1.10.20.5-0.0-0.80.31.80.2-0.80.50.50.50.21.81.4-1.30.30.20.9-0.6
Bone: cortical tissue density1.72.25.21.3-1.4-1.6-1.41.2-1.50.3-0.9-2.1-0.9-1.6-1.62.21.32.30.91.71.80.6-1.4
Condit. Reinf. active minus inactive responses0.10.10.4-0.1-0.4-0.1-0.40.5-0.5-0.6-0.5-0.1-0.5-0.1-0.1-0.2-0.1-0.10.2-0.1-0.0-0.50.0
Condit. Reinf. active-inactive response ratio0.20.31.60.2-0.3-0.2-0.20.8-0.8-0.4-0.2-0.0-0.4-0.3-0.20.0-1.3-0.21.00.00.3-0.6-0.3
Condit. Reinf. active responses0.50.61.80.6-1.1-0.3-1.10.9-1.0-1.3-1.3-0.5-1.3-0.3-0.40.11.00.1-0.10.0-0.1-1.10.2
Condit. Reinf. inactive responses0.80.94.11.0-1.2-0.5-1.30.8-0.8-1.5-1.5-0.8-1.3-0.5-0.60.42.00.5-0.30.3-0.1-0.80.4
Incentive salience index mean0.10.10.5-0.1-0.20.2-0.20.3-0.3-0.6-0.40.2-0.50.30.2-0.5-0.0-0.4-0.1-0.4-0.4-0.70.2
Condit. Reinf. lever presses0.10.10.60.3-0.40.3-0.40.3-0.3-0.8-0.5-0.2-0.50.1-0.0-0.10.70.0-0.1-0.0-0.1-0.4-0.2
Condit. Reinf. active minus inactive responses0.50.61.7-0.40.60.90.5-0.30.4-0.20.31.10.20.80.8-0.8-0.9-1.3-0.5-1.1-1.1-0.80.8
Condit. Reinf. active-inactive response ratio0.30.30.8-0.30.30.60.2-0.20.2-0.3-0.10.7-0.10.50.7-0.6-0.2-0.9-0.7-0.9-0.9-0.70.9
Condit. Reinf. active responses0.10.10.70.4-0.1-0.0-0.10.4-0.3-0.5-0.00.2-0.2-0.1-0.10.1-0.8-0.30.70.00.1-0.3-0.1
Condit. Reinf. inactive responses0.40.51.21.0-0.8-0.7-0.71.0-0.9-0.9-0.6-0.6-0.7-0.7-0.80.7-0.20.41.10.60.7-0.3-0.4
Condit. Reinf. lever presses0.71.02.41.1-1.2-0.8-1.11.5-1.4-1.5-1.0-0.7-1.1-0.9-0.90.8-0.10.41.40.70.8-0.6-0.7
Condit. Reinf. lever reinforcers received0.20.31.70.4-0.2-0.4-0.10.5-0.4-0.50.1-0.2-0.1-0.6-0.60.5-1.00.11.30.60.70.2-0.7
Conditioned reinforcement - actives1.01.02.41.6-0.9-0.7-0.70.8-0.7-0.6-0.6-1.1-0.5-1.2-1.21.30.61.11.11.21.20.6-1.1
Conditioned reinforcement - inactives0.20.20.50.20.50.50.5-0.50.50.70.40.40.40.50.5-0.3-0.4-0.3-0.5-0.4-0.40.10.3
Conditioned locomotion1.31.63.11.5-1.0-0.9-0.81.0-0.8-0.6-0.5-1.4-0.5-1.8-1.71.50.21.41.71.71.70.9-1.7
Patch foraging indifference point 0 sec0.81.33.41.8-1.3-1.0-1.11.1-1.2-1.3-1.0-1.2-1.0-1.2-1.31.30.51.01.31.31.10.1-0.9
Patch foraging indifference point AUC1.82.05.41.5-1.8-1.4-1.91.8-1.8-2.3-2.1-0.8-2.2-1.1-1.00.51.40.20.10.1-0.0-1.71.0
Delay disc. indifference point, 0s delay1.61.84.2-1.40.92.10.7-0.90.80.60.31.40.31.91.8-1.8-0.3-1.4-1.8-1.8-1.8-1.20.9
Delay disc. indifference point, 16s delay0.20.21.00.5-0.5-0.3-0.40.6-0.5-1.0-0.4-0.3-0.5-0.5-0.40.30.20.10.60.30.3-0.2-0.4
Delay disc. indifference point, 2s delay0.60.73.5-0.30.71.90.7-0.50.7-0.20.41.00.41.21.0-0.9-0.4-1.1-0.6-0.9-0.9-0.4-0.3
Delay disc. indifference point, 24s delay0.10.10.30.1-0.20.2-0.30.3-0.4-0.5-0.40.0-0.40.10.0-0.10.2-0.1-0.1-0.2-0.2-0.6-0.1
Delay disc. indifference point, 4s delay1.61.73.4-1.41.11.81.0-0.80.90.10.51.70.51.71.7-1.8-0.6-1.8-1.4-1.7-1.8-1.00.9
Delay disc. indifference point, 8s delay4.24.37.5-2.12.12.51.9-1.71.90.61.42.71.32.62.6-2.6-1.3-2.7-1.9-2.5-2.5-0.91.7
Indifference point function ln k1.01.45.0-0.30.50.10.7-0.90.62.21.2-0.91.4-0.3-0.41.2-0.11.70.61.31.52.2-2.0
Indifference point function log k1.01.45.0-0.30.50.10.7-0.90.62.21.2-0.91.4-0.3-0.41.2-0.11.70.61.31.52.2-2.0
Patch foraging total patch changes 0 sec1.11.83.71.9-1.5-1.2-1.41.3-1.4-1.3-1.2-1.5-1.2-1.4-1.61.50.61.31.51.51.40.1-1.1
Patch foraging total patch changes 12 sec3.14.07.02.2-2.6-2.3-2.62.3-2.3-2.6-2.7-1.9-2.5-2.2-2.11.52.01.31.11.41.1-1.00.0
Patch foraging total patch changes 18 sec1.82.39.22.1-1.8-1.5-1.61.9-1.6-3.0-1.8-0.9-1.8-1.6-1.60.90.60.21.60.90.8-0.9-0.1
Patch foraging total patch changes 24 sec0.40.41.5-0.10.10.40.10.00.1-1.0-0.30.8-0.40.50.5-0.9-0.6-1.2-0.2-0.8-0.9-1.01.0
Patch foraging total patch changes 6 sec1.72.54.01.8-1.9-1.7-1.91.8-1.9-2.0-1.8-1.6-1.8-1.7-1.71.41.71.21.01.21.1-0.6-0.4
Patch foraging time to switch 0 sec0.30.40.7-0.80.80.40.8-0.70.90.50.70.80.70.50.5-0.8-0.5-0.7-0.4-0.6-0.60.10.6
Patch foraging water rate 0 sec0.50.82.11.3-1.2-0.7-1.21.0-1.1-1.4-1.2-0.8-1.2-0.7-0.70.90.90.50.60.60.5-0.6-0.2
Patch foraging water rate 12 sec0.91.34.10.1-0.4-1.0-0.3-0.2-0.21.10.2-1.50.4-1.1-1.11.50.82.00.91.71.81.8-1.7
Patch foraging water rate 18 sec0.40.61.50.4-0.5-0.8-0.30.5-0.6-0.1-0.0-0.8-0.1-0.9-1.01.0-0.10.91.21.01.20.7-1.1
Patch foraging water rate 24 sec1.52.13.51.5-1.4-1.7-1.21.4-1.2-1.6-1.0-1.5-1.0-1.9-1.91.60.81.31.91.71.70.5-1.1
Patch foraging water rate 6 sec0.30.41.6-0.2-0.4-0.3-0.4-0.1-0.30.7-0.2-1.0-0.0-0.5-0.40.81.21.3-0.10.80.70.7-0.8
Seeking ratio, delayed vs. immediate footshock0.30.41.20.8-0.6-0.4-0.80.7-0.7-0.3-1.0-0.1-1.00.20.00.20.3-0.1-0.6-0.4-0.5-1.10.9
Distance traveled before self-admin1.31.42.7-0.81.01.60.8-0.90.90.40.51.50.51.51.4-1.4-0.6-1.6-1.4-1.6-1.7-0.81.1
Distance traveled after self-admin1.21.43.61.2-1.1-1.4-0.91.3-1.1-1.2-0.6-1.0-0.7-1.7-1.61.3-0.20.81.91.21.40.2-0.8
Extensor digitorum longus weight1.24.78.52.9-2.3-2.1-2.11.9-1.8-1.4-1.8-2.8-1.6-2.1-2.32.62.62.71.62.62.30.8-1.7
Bone: elastic displacement1.21.33.70.8-1.3-1.1-1.40.9-1.20.3-1.1-1.8-1.0-1.0-1.11.31.61.90.11.11.10.2-0.7
Bone: elastic work0.40.63.7-0.80.50.20.5-0.80.51.90.8-0.50.90.20.20.20.41.0-0.50.40.51.1-0.7
Bone: endosteal estimation1.43.016.8-1.41.81.32.3-1.01.6-0.02.41.82.01.01.0-1.8-4.1-1.82.2-0.20.21.1-1.0
Bone: endosteal perimeter4.18.424.9-2.73.53.23.8-2.43.01.03.63.63.22.92.9-3.5-5.0-3.40.6-2.0-1.50.60.1
Epididymis fat weight0.41.04.5-1.00.50.00.7-1.00.91.11.1-0.61.3-0.4-0.40.60.41.10.61.21.12.1-1.5
Delta time in closed arm before/after self-admin0.40.41.3-0.60.70.20.7-0.50.7-0.10.51.00.40.60.5-0.7-0.9-1.2-0.2-0.7-0.7-0.20.7
Delta time in open arm before/after self-admin0.90.92.01.2-1.3-0.6-1.31.4-1.4-1.2-1.4-0.9-1.4-0.4-0.30.51.10.60.20.40.3-0.90.1
Diff in mean of infusions in LGA sessions1.11.23.5-0.81.20.51.5-0.91.10.51.80.61.6-0.0-0.0-0.1-1.9-0.31.50.60.71.7-1.4
Delay discount exponential model param1.81.94.41.5-1.3-2.1-1.21.0-1.1-0.1-0.8-1.8-0.7-1.8-1.71.80.71.81.21.61.60.7-0.6
Extinction: sum of active levers before priming0.10.10.3-0.30.10.10.1-0.20.10.50.3-0.30.3-0.3-0.20.30.40.60.10.30.40.5-0.4
Active lever presses in extinction session 60.50.51.70.6-0.2-1.00.1-0.1-0.1-0.40.3-0.50.3-1.1-1.00.5-0.20.61.31.01.00.9-0.7
Bone: final force0.81.34.4-2.01.41.11.2-1.51.22.11.40.81.41.01.0-0.8-0.6-0.3-1.1-0.7-0.60.60.0
Bone: final moment0.91.44.9-2.01.51.11.3-1.51.22.21.50.81.51.11.1-0.8-0.8-0.3-1.0-0.8-0.60.7-0.0
Food consumed during 24 hour testing period0.60.72.60.6-0.10.3-0.20.4-0.3-1.5-0.60.8-0.70.80.8-0.70.0-1.3-0.4-1.1-1.1-1.61.3
Glucose0.30.41.70.00.2-0.40.3-0.30.40.80.6-0.50.7-0.1-0.11.00.30.90.30.80.81.3-0.9
Heart weight0.81.14.4-0.40.60.20.7-1.11.01.91.1-0.61.3-0.4-0.40.80.41.30.01.11.02.1-1.4
Delay discount hyperbolic model param1.61.74.41.3-1.2-2.1-1.10.9-1.1-0.0-0.7-1.7-0.7-1.7-1.71.70.71.81.11.51.60.6-0.4
Intermittent access intake day 1-15 change0.80.73.10.10.20.2-0.00.10.2-0.3-0.40.8-0.40.91.0-0.90.2-1.1-1.3-1.3-1.4-1.31.8
Intermittent access intake escalation0.70.62.70.40.00.0-0.10.4-0.0-0.7-0.50.8-0.60.70.8-0.8-0.1-1.1-0.9-1.1-1.2-1.31.6
Intermittent access intake escalation 20.50.51.81.0-0.4-0.6-0.60.7-0.4-1.1-0.80.2-0.90.10.2-0.10.6-0.5-0.5-0.6-0.7-1.11.3
Intermitt. access day 1 inactive lever presses1.81.93.0-0.91.61.51.6-1.41.41.21.41.71.31.61.6-1.5-1.7-1.6-1.0-1.5-1.3-0.20.9
Intermitt. access day 15 inactive lever presses0.30.30.70.6-0.7-0.7-0.70.8-0.7-0.8-0.8-0.3-0.8-0.4-0.30.10.40.10.10.10.0-0.60.5
Intermitt. access escalation Index1.00.91.9-1.00.80.70.7-0.50.60.00.51.30.41.21.2-1.3-1.0-1.4-0.6-1.2-1.1-0.71.2
Intermittent access day 1 total infusions0.70.83.0-0.30.50.40.8-0.70.71.01.1-0.31.1-0.6-0.60.5-0.60.70.91.01.01.7-1.6
Intermittent access day 15 total infusions0.00.10.30.30.20.10.3-0.00.2-0.10.20.30.10.00.1-0.2-0.6-0.40.1-0.2-0.2-0.10.3
Intermittent access terminal intake (last 3 days)0.20.20.6-0.10.60.40.7-0.40.60.30.60.50.60.20.2-0.4-0.8-0.50.1-0.2-0.20.30.1
Intermittent access total infusions0.30.30.9-0.20.50.30.7-0.50.60.60.80.20.8-0.2-0.2-0.1-1.00.00.60.30.40.9-0.6
Intermittent access day 1 locomotion0.90.92.20.7-0.6-0.6-0.30.5-0.5-0.2-0.0-1.0-0.0-1.4-1.41.1-0.11.11.41.41.41.0-1.5
Intermittent access day 15 total locomotion0.20.20.70.50.30.30.4-0.40.40.70.6-0.10.6-0.3-0.30.4-0.40.30.30.40.40.8-0.6
Intermittent access total locomotion0.50.61.40.9-0.4-0.4-0.20.3-0.30.00.0-0.80.0-1.1-1.11.0-0.00.91.01.11.10.9-1.2
Intermittent access standard deviation3.43.77.0-2.62.42.02.3-2.22.52.22.21.92.21.81.8-1.9-1.2-1.5-1.6-1.4-1.40.90.7
Left kidney weight2.36.511.7-3.23.23.03.1-3.43.43.03.12.43.22.62.5-2.0-1.4-1.7-2.0-1.7-1.71.50.3
Right kidney weight0.82.34.6-1.61.81.91.8-2.12.02.21.71.21.91.61.6-1.1-0.5-0.7-1.5-0.9-1.00.90.1
Cocaine induced anxiety0.91.12.6-1.40.50.60.3-0.30.30.00.01.2-0.11.11.1-1.5-0.3-1.4-1.3-1.6-1.5-1.31.6
Post-drug Anxiety0.40.51.6-0.6-0.2-0.2-0.30.4-0.3-1.0-0.60.6-0.70.10.2-1.00.1-0.9-0.5-0.8-0.8-1.21.3
Baseline Anxiety0.10.10.30.3-0.1-0.1-0.1-0.1-0.00.10.1-0.40.1-0.5-0.40.30.20.50.40.50.50.5-0.5
Tail length0.30.95.41.9-0.6-0.2-0.61.0-0.5-2.3-0.90.4-1.0-0.1-0.00.10.2-1.00.3-0.4-0.5-1.40.9
Length with tail0.93.56.5-1.32.12.62.0-2.12.20.91.62.31.72.32.4-1.8-0.9-2.1-1.7-1.9-2.0-0.21.1
Length without tail3.06.612.9-3.43.13.12.9-3.53.23.62.92.13.02.72.7-2.1-1.1-1.3-2.4-1.7-1.71.30.3
Times rat made contact with spout0.20.31.11.0-0.6-0.4-0.60.6-0.6-1.1-0.7-0.2-0.7-0.2-0.20.40.40.00.30.10.1-0.60.1
Lifetime Intake0.40.41.1-0.60.70.20.8-0.70.70.91.00.21.0-0.1-0.1-0.2-0.90.10.50.30.41.0-0.6
Liver weight, left2.33.78.2-2.92.41.92.4-2.32.32.12.32.02.21.81.8-2.1-1.7-1.5-1.2-1.4-1.30.80.5
Liver weight, right0.71.22.4-1.51.31.41.2-1.51.51.21.10.91.31.01.1-1.20.1-0.6-1.3-0.8-0.90.60.3
Locomotor activity0.00.10.50.3-0.20.5-0.10.1-0.20.1-0.1-0.2-0.10.1-0.00.3-0.20.20.30.20.20.0-0.7
Locomotor testing distance0.20.32.20.20.20.30.40.1-0.00.20.60.10.4-0.1-0.10.3-1.5-0.01.10.30.60.4-1.1
Locomotor testing rearing0.71.12.61.6-1.3-0.7-1.31.5-1.5-1.4-1.3-0.8-1.4-0.7-0.80.80.00.41.00.50.6-0.9-0.4
Locomotion in novel chamber0.60.84.21.0-0.7-0.6-0.71.3-1.0-2.0-0.90.2-1.1-0.3-0.2-0.4-0.4-0.70.8-0.3-0.2-1.30.7
Locomotion in novel chamber post-restriction0.20.32.2-0.20.50.10.60.00.2-0.20.60.80.40.10.2-0.4-1.5-0.90.6-0.4-0.2-0.20.3
Fecal boli incidents, locomotor time 10.91.03.50.2-0.4-0.7-0.10.4-0.30.00.2-1.00.2-0.9-1.10.9-0.41.11.81.51.61.3-1.9
Change in fecal boli incidents, locomotor task0.10.10.3-0.0-0.30.1-0.30.1-0.10.1-0.2-0.5-0.1-0.5-0.50.50.60.60.10.50.40.3-0.5
Time >=10cm from walls, locomotor time 10.30.31.00.30.20.20.10.2-0.0-0.5-0.00.8-0.20.50.5-0.5-0.9-1.0-0.1-0.8-0.7-0.90.9
Bouts of movement, locomotor time 10.20.20.6-0.1-0.10.2-0.1-0.20.00.6-0.1-0.60.1-0.0-0.10.30.60.8-0.20.50.40.7-0.7
Total resting periods, locomotor time 10.20.20.70.0-0.20.1-0.2-0.0-0.10.5-0.1-0.7-0.0-0.2-0.30.40.60.8-0.00.60.50.6-0.8
Rest time, locomotor task time 10.50.52.1-0.80.6-0.00.7-0.90.71.50.9-0.21.0-0.5-0.50.2-0.10.70.10.60.61.4-0.6
Distance moved, locomotor task time 10.50.61.91.3-0.6-0.3-0.70.8-0.7-1.3-0.90.2-1.00.00.20.00.3-0.6-0.2-0.6-0.6-1.40.9
Vertical activity count, locomotor time 11.21.24.22.0-1.3-0.9-1.31.3-1.1-2.0-1.5-0.6-1.5-0.7-0.70.71.10.10.40.30.1-1.00.3
Time >=10cm from walls, locomotor time 20.40.41.71.3-0.7-0.6-0.90.6-0.8-0.3-0.9-0.6-0.9-0.3-0.40.70.70.5-0.30.00.1-0.70.5
Bouts of movement, locomotor time 20.20.30.8-0.30.60.10.7-0.50.60.60.80.40.8-0.10.0-0.1-0.9-0.20.40.10.20.7-0.2
Total resting periods, locomotor time 20.30.31.4-0.40.70.10.8-0.50.60.60.90.40.9-0.2-0.1-0.1-1.2-0.20.60.10.30.8-0.3
Rest time, locomotor task time 21.11.23.2-1.61.20.61.5-1.11.21.11.70.61.6-0.2-0.2-0.4-1.8-0.30.90.40.51.6-0.8
Distance moved, locomotor task time 20.50.62.61.1-0.8-0.1-1.00.4-0.7-0.2-1.2-0.5-1.00.10.10.41.60.4-1.1-0.3-0.4-1.00.4
Vertical activity count, locomotor time 20.30.41.71.2-0.6-0.0-0.60.1-0.2-0.3-0.6-0.7-0.4-0.1-0.30.91.30.7-0.20.50.30.2-0.6
Light reinforcement 11.73.16.22.5-2.2-1.9-2.11.8-1.9-2.0-2.2-1.8-2.0-1.9-1.91.62.11.40.71.21.0-0.6-0.0
Light reinforcement 20.40.52.10.6-0.6-0.5-0.80.2-0.4-0.9-1.0-0.2-0.9-0.4-0.3-0.11.4-0.1-0.8-0.3-0.6-0.81.3
Bone: marrow area1.43.117.1-1.41.81.42.4-1.01.60.02.41.92.01.01.0-1.9-4.1-1.92.1-0.30.11.1-0.9
Bone: maximum diameter5.710.518.0-3.94.13.74.2-3.43.73.14.23.44.03.33.3-3.3-4.1-2.7-0.7-2.0-1.61.6-0.1
Bone: maximum force1.01.75.6-2.21.60.91.6-1.51.42.42.00.71.90.60.6-0.6-1.2-0.0-0.3-0.20.01.5-0.6
Bone: maximum moment1.01.86.1-2.11.70.91.7-1.61.42.52.00.72.00.70.7-0.6-1.4-0.1-0.2-0.20.11.5-0.7
Mean time between licks in bursts0.00.00.2-0.50.00.1-0.00.0-0.00.50.0-0.10.00.20.10.0-0.00.2-0.2-0.00.00.0-0.2
Mean num. licks in bursts0.40.50.90.7-0.8-1.0-0.80.9-0.9-0.3-0.6-0.8-0.7-0.9-0.81.0-0.20.70.80.70.8-0.1-0.5
Cd content in liver1.11.23.40.9-0.9-1.1-0.90.6-0.70.4-0.5-1.6-0.4-1.0-1.01.51.21.80.61.41.40.9-1.1
Co content in liver0.60.71.50.4-0.7-1.2-0.50.7-0.70.1-0.3-1.1-0.4-0.9-0.80.7-0.21.11.11.11.20.6-0.8
Cu content in liver0.00.10.30.20.00.20.0-0.40.10.3-0.0-0.10.10.50.5-0.00.40.2-0.3-0.0-0.00.1-0.0
Fe content in liver0.30.41.5-0.20.30.50.4-0.00.2-0.70.20.90.00.60.6-1.1-1.2-1.10.3-0.6-0.5-0.60.4
K content in liver0.40.41.70.4-0.3-0.0-0.40.4-0.6-0.4-0.60.4-0.70.30.3-0.4-0.3-0.6-0.5-0.8-0.7-1.31.1
Mg content in liver1.51.63.41.8-1.5-1.5-1.51.7-1.8-1.1-1.4-1.1-1.6-1.2-1.31.10.30.80.90.60.8-0.9-0.0
Mn content in liver0.80.91.7-0.80.90.80.7-0.80.80.20.51.20.51.01.1-1.1-0.2-1.2-1.2-1.3-1.3-0.61.2
Na content in liver0.70.71.9-0.30.40.70.3-0.10.00.00.11.0-0.11.11.1-1.1-0.9-1.2-0.8-1.4-1.2-1.31.2
Rb content in liver2.12.64.11.7-2.0-1.9-2.01.9-1.9-1.5-1.8-1.7-1.8-1.8-1.91.81.61.41.01.31.2-0.6-0.4
Se content in liver0.80.93.41.2-0.8-0.3-0.91.1-1.1-1.8-1.30.2-1.40.20.1-0.20.1-0.7-0.1-0.7-0.7-1.81.1
Sr content in liver0.10.10.7-0.10.1-0.10.1-0.30.20.90.2-0.20.20.10.10.20.30.4-0.50.10.00.40.1
Zn content in liver1.11.22.7-1.51.31.41.2-1.21.11.71.20.91.21.31.3-1.1-1.0-0.5-0.8-0.8-0.60.40.0
Bone: minimum diameter2.14.011.2-2.32.32.52.5-1.81.91.82.42.12.22.12.1-2.3-3.3-1.8-0.1-1.4-1.00.5-0.2
Time in familiar zone, hab. session 10.00.00.10.1-0.3-0.1-0.30.1-0.2-0.0-0.3-0.3-0.3-0.2-0.1-0.00.30.3-0.10.20.10.0-0.0
Time in novel zone, hab. session 10.40.40.9-0.60.50.40.4-0.40.30.20.30.80.20.60.7-0.8-0.5-0.9-0.7-1.0-0.8-0.60.9
Total zone transitions, hab. session 11.72.44.91.7-2.0-1.4-2.02.1-2.2-1.4-1.8-1.7-1.9-1.3-1.41.51.31.41.01.01.1-0.9-0.7
Total locomotion distance, hab. session 11.42.14.12.0-1.8-1.1-1.81.6-1.7-1.4-1.7-1.7-1.6-1.2-1.21.61.51.40.81.21.1-0.4-0.8
Locomotion velocity, hab. session 12.02.85.62.4-2.1-1.3-2.01.8-2.0-1.5-1.9-2.0-1.8-1.4-1.52.01.91.81.01.51.4-0.3-1.1
Time in familiar zone, hab. session 20.10.10.60.2-0.2-0.8-0.10.0-0.10.00.0-0.40.1-0.7-0.50.40.10.50.40.50.50.5-0.1
Time in novel zone, hab. session 20.40.40.8-0.90.60.70.6-0.40.40.50.50.70.40.70.6-0.8-0.9-0.7-0.4-0.7-0.6-0.30.3
Total zone transitions, hab. session 25.16.69.62.9-3.0-2.8-2.93.0-3.1-2.1-2.5-3.0-2.6-2.8-2.82.81.72.62.32.42.5-0.3-1.5
Total locomotion distance, hab. session 25.16.811.53.4-3.0-2.8-2.92.6-2.8-2.1-2.6-3.1-2.5-2.9-2.83.12.52.81.92.52.4-0.0-1.5
Locomotion velocity, hab. session 25.16.912.33.5-3.1-2.7-3.02.7-2.9-2.2-2.7-3.1-2.6-2.8-2.73.12.72.81.82.42.3-0.3-1.4
Novel to familiar place preference ratio2.02.13.41.5-1.5-1.8-1.31.6-1.6-0.7-1.0-1.6-1.1-1.7-1.81.6-0.11.51.91.61.80.3-1.1
Novelty place preference1.51.52.91.3-1.3-1.5-1.11.4-1.3-0.7-0.8-1.4-0.9-1.5-1.51.3-0.21.31.71.41.50.2-1.0
Time in novel zone, NPP test1.81.83.11.4-1.4-1.7-1.31.5-1.5-0.8-1.0-1.5-1.0-1.7-1.71.5-0.01.41.81.51.70.2-1.0
Total zone transitions, NPP test3.65.18.02.8-2.8-2.3-2.82.6-2.8-2.2-2.6-2.5-2.6-2.2-2.22.32.22.11.41.81.7-0.8-0.8
Total locomotion distance, NPP test6.79.216.54.1-3.6-3.0-3.52.9-3.2-2.5-3.1-3.6-2.9-3.0-3.03.73.43.31.92.92.7-0.1-1.7
Locomotion velocity, NPP test5.68.014.03.7-3.3-2.8-3.22.7-3.0-2.3-2.9-3.4-2.7-2.8-2.93.43.13.11.82.72.5-0.1-1.7
Intraocular pressure0.91.25.21.2-0.5-1.5-0.10.5-0.3-1.20.1-0.70.1-1.4-1.40.9-0.70.62.31.51.51.2-1.1
Delta distance traveled before/after self-admin2.93.15.71.6-1.8-2.4-1.61.9-1.8-1.2-1.2-2.0-1.2-2.3-2.21.90.71.92.22.02.20.4-1.2
Delta ambulatory time before/after self-admin3.23.57.01.7-1.9-2.7-1.62.1-2.0-1.5-1.2-2.0-1.4-2.5-2.42.00.41.92.52.02.30.4-1.1
Parametrial fat weight0.00.10.5-0.10.10.00.2-0.50.40.20.2-0.10.3-0.2-0.2-0.10.20.30.10.40.20.7-0.3
Pavlov. Cond. lever latency0.60.72.81.0-0.5-1.6-0.30.8-0.5-0.7-0.1-0.4-0.2-1.3-1.10.6-1.10.21.70.91.00.4-0.1
Pavlov. Cond. magazine entry latency1.92.54.7-1.51.72.21.6-1.41.40.81.21.91.12.01.9-2.0-1.2-1.9-1.5-1.9-1.8-0.61.0
Pavlov. Cond. change in total contacts0.40.41.60.0-0.5-0.1-0.50.4-0.60.5-0.2-1.0-0.2-0.5-0.60.90.61.20.30.80.90.5-1.3
Pavlov. Cond. index score1.21.54.1-1.41.22.01.1-1.31.20.80.91.20.91.71.5-1.3-0.1-1.1-1.4-1.3-1.3-0.20.3
Pavlov. Cond. latency score1.62.05.2-1.61.42.31.3-1.61.41.01.01.41.02.01.8-1.5-0.0-1.2-1.8-1.5-1.6-0.20.5
Pavlov. Cond. lever contacts0.20.21.3-0.50.11.0-0.1-0.40.10.4-0.1-0.10.00.70.50.01.10.3-1.0-0.2-0.3-0.1-0.3
Pavlov. Cond. magazine entry number2.43.05.72.2-2.0-2.4-1.91.8-1.8-1.4-1.7-2.0-1.7-2.1-1.91.91.31.71.41.71.6-0.0-0.5
Pavlov. Cond. intertrial magazine entries1.51.93.01.5-1.7-1.7-1.61.7-1.7-1.5-1.5-1.4-1.5-1.6-1.61.20.81.11.21.11.1-0.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.81.03.1-1.11.01.80.9-1.00.80.70.61.00.61.51.3-1.1-0.1-0.9-1.2-1.1-1.1-0.30.2
Pavlov. Cond. response bias1.11.33.4-1.51.21.81.1-1.21.11.11.01.11.01.51.4-1.2-0.6-0.9-1.2-1.1-1.1-0.10.1
Pavlov. Cond. lever latency0.91.24.3-1.31.00.80.8-1.41.21.50.60.80.81.11.2-1.00.6-0.5-2.1-1.1-1.30.01.3
Pavlov. Cond. magazine entry latency0.81.02.90.4-0.3-0.70.00.2-0.10.00.4-0.90.4-1.1-1.21.0-0.31.01.61.51.51.5-1.7
Pavlov. Cond. change in total contacts0.91.24.01.1-0.9-1.0-0.61.1-0.8-0.9-0.3-1.0-0.4-1.3-1.41.3-0.40.92.01.51.60.8-1.6
Pavlov. Cond. index score0.70.93.61.0-0.7-0.5-0.40.9-0.6-0.9-0.2-0.8-0.3-1.0-1.10.9-0.50.71.91.31.30.6-1.6
Pavlov. Cond. latency score0.50.63.00.7-0.4-0.3-0.20.7-0.4-0.70.0-0.5-0.1-0.8-0.90.7-0.70.41.71.11.10.7-1.4
Pavlov. Cond. lever contacts0.81.13.11.4-1.2-0.5-1.01.6-1.4-1.8-1.0-0.7-1.2-0.8-0.80.8-0.40.21.70.70.8-0.6-0.9
Pavlov. Cond. magazine entry number1.01.23.2-1.20.70.80.4-0.70.50.50.11.10.11.31.4-1.20.0-1.2-1.8-1.6-1.6-1.11.7
Pavlov. Cond. intertrial magazine entries0.81.04.10.9-0.50.4-0.60.8-0.8-1.8-1.00.7-1.20.60.7-0.6-0.6-1.4-0.0-1.0-1.0-2.01.1
Pavlov. Cond. lever-magazine prob. diff.0.81.04.01.1-0.8-0.6-0.41.0-0.7-1.0-0.2-0.8-0.3-1.1-1.21.0-0.50.72.01.31.40.6-1.6
Pavlov. Cond. response bias0.70.92.61.2-1.0-0.5-0.81.1-0.9-1.2-0.6-0.9-0.7-0.9-1.01.0-0.10.71.61.11.10.2-1.3
Time in closed arm before self-admin0.10.11.00.1-0.20.1-0.3-0.1-0.10.5-0.2-0.5-0.1-0.2-0.20.31.00.7-0.50.20.10.2-0.1
Time in closed arm after self-admin1.81.83.5-1.81.81.21.8-1.71.81.81.81.31.91.00.9-1.0-1.3-0.9-0.5-0.6-0.61.1-0.0
Time in open arm before self-admin0.30.30.7-0.60.6-0.00.6-0.60.50.60.60.60.50.50.4-0.7-0.8-0.5-0.3-0.5-0.40.00.6
Time in open arm after self-admin0.50.51.21.0-0.9-1.1-0.81.0-0.9-1.1-0.8-0.6-0.9-0.6-0.60.30.40.30.60.30.4-0.60.4
Bone: periosteal estimation2.34.710.7-2.72.72.33.0-2.22.42.13.11.92.91.91.9-2.1-3.3-1.40.6-0.6-0.21.8-1.0
Bone: periosteal perimeter4.67.712.5-3.43.53.43.5-3.13.32.93.52.73.43.03.0-2.8-2.8-2.1-1.2-1.8-1.51.3-0.0
Bone: post-yield work0.71.03.00.8-0.6-1.2-0.40.9-0.8-0.2-0.1-0.9-0.3-1.3-1.41.1-0.80.91.71.21.40.7-1.1
Progressive ratio test 1 active lever presses0.20.20.90.3-0.1-0.30.00.3-0.2-0.40.1-0.10.0-0.6-0.50.0-0.80.01.00.40.50.2-0.4
Progressive ratio test 1 breakpoint0.20.21.00.0-0.0-0.40.20.1-0.0-0.10.3-0.20.2-0.6-0.50.0-0.80.21.00.50.60.5-0.5
Progressive ratio test 1 inactive lever presses0.20.30.70.10.50.80.5-0.30.40.20.30.70.30.60.6-0.6-0.7-0.7-0.4-0.7-0.6-0.30.4
Progressive ratio test 2 active lever presses0.50.51.51.1-0.2-0.40.00.1-0.1-0.10.3-0.60.2-0.8-0.91.0-0.40.71.21.01.00.9-1.1
Progressive ratio test 2 breakpoint0.40.51.21.1-0.3-0.5-0.10.2-0.2-0.10.1-0.60.1-0.8-0.90.9-0.30.71.10.91.00.8-1.0
Progressive ratio test 2 inactive lever presses0.00.00.60.80.1-0.10.1-0.10.10.20.2-0.00.2-0.2-0.10.2-0.20.10.10.10.10.2-0.0
Incentive Sensitization - Responses0.50.51.10.30.81.00.9-1.10.90.91.00.31.10.40.30.0-0.4-0.0-0.20.0-0.00.9-0.6
Incentive Sensitization - Breakpoint0.60.61.40.11.01.11.1-1.21.11.01.10.51.20.60.5-0.1-0.4-0.2-0.3-0.2-0.20.9-0.5
Sum of active levers in priming session hrs 5-60.50.51.9-0.50.70.20.9-0.40.60.51.10.30.9-0.1-0.1-0.3-1.4-0.11.00.30.51.0-0.8
Progressive ratio0.70.83.1-0.10.30.10.6-0.40.50.70.9-0.40.9-0.7-0.70.5-0.80.71.21.21.21.7-1.8
Food seeking constrained by brief footshock0.60.81.5-1.21.01.01.1-1.21.21.21.10.51.20.50.5-0.2-0.5-0.2-0.3-0.0-0.21.2-0.8
Seeking ratio, punishment vs. effort0.50.61.5-0.50.40.70.2-0.30.3-0.1-0.10.9-0.11.11.0-0.80.1-1.0-1.2-1.2-1.2-1.01.1
Retroperitoneal fat weight0.41.33.9-1.01.51.01.7-1.72.00.51.61.11.70.70.7-0.8-0.6-0.8-0.1-0.1-0.31.5-0.3
Reaction time number correct2.63.79.42.6-2.3-2.5-2.12.4-2.2-3.1-2.1-1.6-2.2-1.9-1.91.41.31.01.91.41.3-0.8-0.2
Reaction time mean minus median0.40.61.6-0.40.80.90.7-1.10.91.10.50.60.70.90.8-0.60.0-0.4-1.3-0.7-0.80.20.6
Reaction time mean minus median AUC0.91.12.5-0.80.91.20.8-1.10.90.80.51.20.51.31.3-1.2-0.3-1.1-1.6-1.4-1.4-0.61.3
Reaction time num false alarms0.10.20.70.8-0.20.0-0.10.10.0-0.3-0.1-0.40.0-0.5-0.40.70.10.30.60.70.50.5-0.8
Reaction time num false alarms AUC0.30.41.21.1-0.5-0.3-0.30.4-0.3-0.5-0.3-0.6-0.2-0.9-0.71.0-0.00.51.00.90.80.5-0.9
Reaction time trials correct on left2.63.79.42.6-2.3-2.5-2.12.4-2.2-3.1-2.1-1.6-2.2-1.9-1.91.41.31.01.91.41.3-0.8-0.2
Reaction time trials on left2.53.69.42.6-2.3-2.5-2.12.4-2.2-3.1-2.1-1.6-2.1-1.9-1.91.41.31.01.91.31.3-0.8-0.2
Reaction time mean0.00.10.4-0.10.30.30.3-0.30.30.70.30.10.30.10.1-0.2-0.40.0-0.2-0.0-0.00.2-0.1
Reaction time mean AUC0.00.10.40.10.10.10.1-0.20.10.60.2-0.20.2-0.1-0.20.1-0.20.40.00.30.30.4-0.3
Median of all reaction times0.00.00.3-0.10.20.30.2-0.10.10.60.2-0.00.20.1-0.0-0.1-0.50.10.10.10.10.2-0.3
Reaction time omissions0.50.71.4-0.70.90.90.8-1.01.10.60.60.90.71.21.2-0.9-0.3-0.9-1.0-0.8-0.9-0.00.7
Reaction time false alarm rate0.30.41.1-0.30.71.00.7-0.80.81.10.70.30.80.30.40.1-0.6-0.1-0.10.0-0.10.8-0.6
Reaction time premature initiation rate2.53.36.11.0-2.0-2.0-1.91.8-2.0-0.5-1.4-2.4-1.4-2.3-2.22.01.52.51.52.02.10.4-1.5
Reaction time premature initiations4.86.710.42.3-2.9-3.2-2.72.9-2.9-2.0-2.2-3.1-2.3-3.2-3.12.71.82.82.62.72.80.1-1.7
Std. dev. reaction times0.10.10.50.00.20.20.2-0.50.40.70.20.00.30.20.2-0.10.10.1-0.5-0.1-0.20.20.1
Reaction time trials completed2.53.69.42.6-2.3-2.5-2.12.4-2.2-3.1-2.1-1.6-2.1-1.9-1.91.41.31.01.91.31.3-0.8-0.2
Reaction time trials AUC3.04.310.42.7-2.5-2.7-2.32.6-2.4-3.2-2.2-1.8-2.3-2.1-2.11.61.41.22.01.51.5-0.9-0.3
Run reversals in cocaine runway, females0.20.20.6-0.50.40.80.5-0.60.60.10.40.20.60.30.1-0.40.4-0.1-0.00.2-0.00.6-0.6
Run reversals in cocaine runway, males0.60.62.6-0.60.3-0.30.4-0.60.61.10.7-0.60.9-0.6-0.50.80.61.00.31.00.81.6-0.9
Latency to leave start box in cocaine runway0.50.61.30.6-0.5-0.9-0.40.3-0.40.3-0.0-0.90.0-1.1-1.11.20.11.10.91.11.10.8-0.7
Latency to leave start box in cocaine runway, F0.50.61.80.8-0.8-1.3-0.80.6-0.7-0.4-0.7-0.8-0.6-1.1-1.10.90.40.70.60.70.70.00.1
Latency to leave start box in cocaine runway, M1.11.02.40.9-0.7-0.7-0.50.6-0.60.1-0.1-1.3-0.1-1.0-1.21.40.41.51.31.51.51.0-1.5
Std. dev. time between licks in bursts1.21.43.81.8-1.5-1.2-1.41.7-1.5-2.0-1.5-0.9-1.5-1.0-1.00.70.60.51.00.70.6-0.90.0
Total sessions with >9 infusions1.01.12.6-1.51.20.71.4-1.31.21.61.60.51.60.20.3-0.7-1.2-0.10.10.10.21.4-0.7
Short access day 1 total inactive lever presses0.30.31.2-0.60.70.30.8-0.70.60.80.90.50.80.30.3-0.5-1.1-0.30.1-0.2-0.00.4-0.0
Short access day 10 total inactive lever presses1.01.22.4-1.00.90.80.7-0.70.70.60.51.20.41.31.4-1.4-0.7-1.3-1.3-1.5-1.4-0.91.5
Short access day 1 total infusions1.01.02.3-1.31.30.71.4-1.51.21.51.50.71.50.60.6-0.8-1.1-0.3-0.1-0.2-0.11.1-0.3
Short access day 10 total infusions1.41.63.7-1.51.51.11.7-1.61.51.31.91.01.90.50.5-0.9-1.9-0.60.5-0.10.11.4-0.7
Short access total infusions0.40.51.4-0.70.60.10.8-0.90.71.11.00.01.1-0.2-0.1-0.1-0.60.30.40.40.51.2-0.6
Short access day 1 locomotion0.30.31.2-1.10.60.60.6-0.80.61.00.70.20.80.20.3-0.4-0.10.1-0.3-0.1-0.00.6-0.3
Short access day 10 total locomotion0.30.31.1-0.80.70.60.7-0.90.71.10.80.20.90.20.2-0.3-0.40.1-0.2-0.00.00.7-0.4
Short access total locomotion0.90.93.9-1.21.00.91.0-1.41.12.01.30.11.40.20.3-0.2-0.10.4-0.50.20.21.4-0.7
One hour access (0.3 mA shock)0.30.41.60.2-0.2-0.70.00.3-0.1-0.30.2-0.40.2-0.9-0.80.4-0.40.51.20.90.90.8-0.7
Compulsive drug intake0.60.61.30.9-0.7-1.1-0.60.4-0.5-0.2-0.4-1.0-0.4-1.0-1.00.90.81.10.61.00.90.6-0.5
One hour access (shock baseline)0.10.10.40.00.20.30.30.10.2-0.40.20.40.20.00.1-0.3-0.6-0.50.4-0.1-0.1-0.0-0.0
Social response proportion0.50.51.50.4-0.6-0.6-0.50.4-0.3-0.3-0.4-1.0-0.3-0.8-0.70.91.21.10.51.00.90.7-0.8
Social responses0.20.32.30.2-0.6-0.2-0.70.4-0.5-0.5-0.8-0.4-0.7-0.00.00.21.50.3-0.6-0.1-0.2-0.60.4
Social time0.60.71.70.9-0.9-0.8-0.90.6-0.7-0.2-0.8-1.2-0.6-0.7-0.81.11.31.30.31.10.90.4-0.8
Soleus weight0.72.18.21.9-1.6-1.2-1.61.0-1.2-0.7-1.5-1.9-1.3-1.2-1.31.72.91.9-0.01.31.00.2-0.7
Bone: stiffness1.11.85.3-2.31.71.31.6-1.61.62.11.71.01.71.11.1-0.9-0.7-0.4-0.9-0.7-0.61.0-0.1
Tibialis anterior weight0.20.61.71.0-0.7-0.5-0.70.6-0.6-0.1-0.5-1.2-0.4-0.6-0.70.91.21.30.40.90.90.5-0.8
Time to tail flick, vehicle, before self-admin0.80.83.10.8-1.1-0.3-1.30.8-1.1-0.7-1.4-0.9-1.20.10.00.31.80.8-0.60.10.0-0.90.4
Time to tail flick, vehicle, after self-admin1.11.25.0-1.51.30.61.3-1.61.42.21.50.31.60.30.4-0.3-0.20.3-0.70.10.11.7-0.5
Time to tail flick, test, before self-admin0.30.31.10.9-0.60.2-0.60.6-0.7-1.0-0.8-0.0-0.80.20.2-0.2-0.0-0.30.1-0.2-0.2-1.10.2
Time to tail flick, test, after self-admin0.60.61.4-0.81.00.71.0-1.11.20.71.00.71.10.80.7-0.8-0.5-0.4-0.3-0.3-0.30.60.1
Delta time to tail flick, vehicle, before/after SA0.60.62.2-0.40.6-0.20.9-0.60.70.81.00.11.0-0.6-0.50.2-1.10.20.80.60.61.5-1.0
Delta time to tail flick, test, before/after SA1.11.02.3-1.51.30.61.2-1.51.51.51.30.61.40.70.6-0.5-0.0-0.2-0.8-0.3-0.41.10.1
Tibia length10.128.441.1-6.36.26.25.8-6.36.44.65.05.95.36.16.2-5.3-2.5-5.1-5.4-5.0-5.30.63.1
Ambulatory time before self-admin1.92.04.2-0.61.32.01.1-1.31.20.70.71.70.71.81.8-1.4-0.5-1.7-1.9-1.8-2.0-0.81.2
Ambulatory time after self-admin0.50.51.60.7-0.6-1.0-0.50.8-0.8-0.7-0.3-0.5-0.4-1.2-1.10.7-0.50.41.30.70.80.0-0.4
Bone: tissue strength1.21.22.40.9-0.7-1.4-0.50.7-0.80.4-0.1-1.2-0.2-1.5-1.51.5-0.51.31.41.41.60.9-1.2
Total heroin consumption2.22.55.2-1.72.11.42.2-1.92.01.92.31.52.21.21.3-1.1-2.2-1.0-0.2-0.7-0.51.3-0.2
Bone: trabecular number0.30.51.50.8-0.6-0.7-0.61.2-1.0-1.0-0.6-0.1-0.9-0.4-0.40.0-0.6-0.20.8-0.10.1-1.00.4
Bone: trabecular spacing0.30.31.0-0.70.60.90.7-1.01.00.40.50.40.70.40.4-0.30.1-0.3-0.40.0-0.30.8-0.4
Bone: trabecular thickness0.40.51.50.9-0.7-0.7-0.61.2-1.1-0.5-0.4-0.7-0.7-0.5-0.50.4-0.60.61.20.50.9-0.3-0.6
Bone: trabecular tissue density0.20.31.5-0.20.21.10.1-0.80.7-0.1-0.10.20.20.60.6-0.21.2-0.2-1.0-0.2-0.70.10.1
Water consumed over 24 hours0.60.72.11.1-0.7-0.4-0.90.7-0.8-1.4-1.2-0.0-1.2-0.00.10.01.1-0.4-0.6-0.6-0.6-1.41.2
Number of responses in last shaping day1.61.73.4-1.51.51.81.5-1.61.51.71.51.11.51.51.4-1.2-0.8-0.7-1.1-0.9-0.90.6-0.1