Hub : Genes

Dnah17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Dnah17 0.16 0.09 1.8e-15 0.13 0.14 0.13 0.14 2.5e-14 1.5e-14 2.8e-14 2.9e-15
2 IC gene expression Dnah17 0.43 0.16 1.1e-10 0.12 0.21 0.2 0.2 1.5e-05 2.9e-09 1.0e-08 7.1e-09
3 Adipose mRNA stability Dnah17 0.02 0.01 5.6e-03 0.02 0.01 0.01 0.01 2.1e-03 3.4e-02 2.3e-02 1.7e-02
4 BLA mRNA stability Dnah17 0.36 0.14 1.2e-11 0.19 0.19 0.18 0.19 3.4e-10 3.2e-10 6.5e-10 1.6e-10
5 OFC gene expression Dnah17 0.23 0.13 2.3e-04 0.03 0.09 0.05 0.06 5.7e-02 4.2e-03 2.4e-02 1.5e-02
6 PL gene expression Dnah17 0.38 0.13 0.0e+00 0.26 0.28 0.27 0.27 9.4e-29 4.9e-30 5.9e-30 3.6e-29
7 OFC mRNA stability Dnah17 0.17 0.12 3.0e-03 0.06 0.02 0.02 0.02 1.9e-02 9.0e-02 1.0e-01 9.6e-02
8 BLA gene expression Dnah17 0.46 0.14 0.0e+00 0.32 0.32 0.31 0.32 3.0e-17 2.1e-17 1.1e-16 2.6e-17
9 IL gene expression Dnah17 0.39 0.16 4.3e-09 0.22 0.24 0.2 0.22 5.9e-06 1.7e-06 1.8e-05 5.4e-06
10 Brain intron excision ratio chr10_103769309_103770227 0.02 0.01 9.4e-03 0.01 0.01 0 0.01 4.3e-02 1.5e-02 9.2e-02 4.9e-02
11 IC mRNA stability Dnah17 0.17 0.16 4.1e-03 0.05 0.04 0.04 0.04 2.8e-03 6.9e-03 1.2e-02 8.7e-03
12 IL mRNA stability Dnah17 0.3 0.15 6.6e-07 0.17 0.2 0.18 0.17 8.5e-05 1.6e-05 3.2e-05 7.9e-05
13 LHb gene expression Dnah17 0.44 0.18 8.9e-08 0.22 0.25 0.24 0.23 7.8e-06 9.7e-07 1.6e-06 3.0e-06
14 NAcc mRNA stability Dnah17 0.07 0.04 2.7e-08 0.06 0.05 0.06 0.05 5.6e-09 2.3e-08 1.0e-08 1.2e-08
15 RMTg gene expression Dnah17 0.53 0.19 4.3e-09 0.31 0.32 0.3 0.32 7.8e-09 2.2e-09 1.6e-08 3.5e-09
16 NAcc gene expression Dnah17 0.19 0.09 0.0e+00 0.12 0.13 0.13 0.13 5.6e-17 4.5e-19 1.5e-19 7.9e-19
17 LHb mRNA stability Dnah17 0.47 0.19 1.0e-06 0.14 0.23 0.18 0.18 3.6e-04 4.0e-06 3.8e-05 3.6e-05
18 pVTA gene expression Dnah17 0.66 0.14 0.0e+00 0.39 0.44 0.44 0.43 1.6e-33 8.6e-39 4.8e-38 1.5e-37
19 pVTA mRNA stability Dnah17 0.21 0.18 5.6e-08 0.08 0.09 0.13 0.1 8.4e-07 1.9e-07 6.8e-11 2.0e-08
20 Brain mRNA stability Dnah17 0.41 0.15 0.0e+00 0.2 0.24 0.24 0.2 4.2e-18 7.2e-22 7.8e-22 7.4e-19
21 Brain gene expression Dnah17 0.54 0.26 0.0e+00 0.15 0.22 0.22 0.2 3.0e-14 3.5e-20 9.5e-21 1.6e-18

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.11.94.3-1.6-1.40.5-1.5-1.7-1.3-1.1-1.1-1.0-1.5-1.5-1.01.11.41.91.40.91.72.11.10.7
Area under the delay curve1.21.43.30.80.2-0.40.60.90.60.60.51.41.10.71.5-1.7-1.4-1.1-1.6-1.8-1.4-1.4-1.5-1.5
BMI with tail0.51.65.71.12.4-0.81.00.91.61.31.7-0.30.41.0-0.81.30.5-0.21.22.10.80.01.62.1
BMI without tail0.41.22.9-0.6-0.11.5-0.7-0.7-0.5-0.7-0.4-1.4-1.0-0.6-1.61.61.20.71.51.71.00.31.51.5
Body weight0.62.78.12.32.9-1.42.12.12.52.22.51.11.62.10.7-0.3-0.9-1.4-0.10.4-0.8-1.30.10.7
Weight adjusted by age0.00.10.30.2-0.3-0.10.2-0.30.10.30.10.3-0.20.00.3-0.30.20.60.3-0.30.20.20.1-0.0
Bone surface0.51.03.30.7-0.3-1.30.50.00.70.90.81.60.50.71.7-1.7-0.80.4-0.6-1.8-0.21.1-0.8-1.0
Bone volume0.20.41.80.0-0.6-0.8-0.1-0.70.20.40.30.6-0.30.10.7-0.60.11.20.4-0.70.71.30.1-0.2
Breakpoint value in progressive ratio session0.70.93.60.80.4-0.81.0-0.31.01.11.20.5-0.20.90.4-0.10.61.21.00.11.21.91.01.4
Number of licking bursts0.00.10.40.10.20.1-0.00.20.20.20.10.10.20.10.1-0.2-0.3-0.3-0.2-0.1-0.4-0.6-0.2-0.3
Context. condit. distance diff. score0.20.30.50.60.3-0.70.70.30.70.70.70.70.40.70.7-0.7-0.30.0-0.2-0.6-0.20.7-0.20.1
Locomotion velocity, session 11.11.23.70.30.5-0.20.41.20.20.40.00.71.20.40.8-0.9-1.3-1.6-1.7-0.9-1.5-1.9-1.5-1.6
Locomotion distance, session 12.22.84.5-1.9-1.42.0-1.8-1.6-1.9-1.8-1.9-2.1-1.8-1.8-2.12.01.71.21.41.71.40.51.31.0
Locomotion velocity, session 20.50.61.2-1.1-0.70.7-0.9-0.7-1.0-0.7-1.0-0.9-0.8-0.8-1.00.90.80.60.50.80.7-0.10.50.2
Locomotion distance, session 25.37.310.6-3.2-2.32.8-3.0-2.7-3.1-2.9-3.0-3.2-2.9-3.0-3.33.12.82.22.22.72.51.32.01.3
Locomotion velocity, session 30.40.51.5-0.1-0.30.6-0.20.5-0.3-0.4-0.50.20.50.00.4-0.7-0.9-1.0-0.9-0.9-1.1-1.0-1.1-1.2
Locomotion distance, session 30.30.31.0-0.30.30.6-0.4-0.0-0.2-0.4-0.2-0.8-0.3-0.2-0.90.90.4-0.10.81.00.30.30.60.9
Stereotopy head waving bouts, day 31.82.14.11.81.6-1.82.01.41.81.91.81.71.51.91.6-1.3-1.2-0.9-1.1-1.0-0.9-0.9-0.8-0.6
Stereotopy head waving duration, day 31.72.03.61.71.2-1.81.91.21.61.81.71.81.41.71.7-1.5-1.2-0.8-1.1-1.2-0.8-0.6-0.9-0.9
Locomotion velocity, session 70.20.20.6-0.4-0.80.5-0.5-0.3-0.5-0.5-0.50.0-0.2-0.40.2-0.4-0.10.1-0.4-0.7-0.10.6-0.4-0.4
Locomotion distance, session 73.03.85.4-2.0-2.01.8-2.1-2.3-1.8-2.0-1.7-1.9-2.3-2.0-1.81.72.12.31.81.32.12.21.71.4
Stereotopy head waving bouts, day 74.14.66.52.52.0-2.32.52.22.42.42.32.52.32.42.5-2.3-2.1-1.8-1.8-1.9-1.9-1.2-1.6-1.3
Stereotopy head waving duration, day 75.46.59.52.72.1-2.72.72.62.62.82.53.12.82.63.0-2.8-2.6-2.2-2.3-2.5-2.4-1.3-2.3-2.0
Locomotion velocity, session 80.70.82.40.4-0.2-0.50.50.50.20.60.21.20.80.41.3-1.4-1.0-0.6-1.6-1.6-0.9-0.3-1.3-1.3
Locomotion distance, session 82.43.54.7-1.9-1.81.6-1.7-2.2-1.8-1.6-1.6-2.0-2.2-1.6-2.01.92.12.12.01.62.12.11.81.5
Degree of sensitization distance3.13.26.8-2.1-2.61.7-2.0-2.5-2.0-2.0-1.9-1.4-2.2-2.1-1.10.91.72.41.20.41.81.91.00.5
Degree of sensitization stereotypy1.51.62.31.51.2-1.21.41.41.51.31.41.51.41.41.5-1.4-1.3-1.1-1.0-1.2-1.2-0.8-0.9-0.7
Conditioned locomotion0.30.31.2-0.4-0.61.1-0.4-0.7-0.4-0.8-0.4-0.5-0.7-0.4-0.40.40.40.80.60.30.60.20.50.1
Cocaine response after cond. corrected0.20.30.90.70.8-0.60.90.50.70.50.80.40.40.90.3-0.1-0.1-0.20.00.1-0.1-0.30.10.1
Cocaine response after cond. not corrected0.10.10.20.30.1-0.40.40.20.20.10.20.30.30.50.3-0.3-0.2-0.2-0.3-0.3-0.3-0.3-0.3-0.4
Cocaine response before conditioning0.50.61.8-0.9-1.40.4-1.0-0.5-1.1-0.8-1.10.0-0.3-1.00.3-0.6-0.30.1-0.7-1.0-0.40.3-0.8-1.1
Saline control response1.21.63.8-1.2-1.61.5-1.2-0.2-1.7-1.4-1.8-0.20.1-1.20.2-0.7-0.9-1.0-1.7-1.4-1.4-1.0-1.7-1.9
Bone: connectivity density1.42.25.9-2.0-2.01.1-2.0-1.8-1.8-1.5-1.7-1.0-1.5-2.0-0.80.61.21.60.80.21.22.40.40.1
Bone: cortical apparent density1.72.35.6-1.5-0.30.8-1.3-1.1-1.2-0.8-1.1-1.8-1.4-1.4-2.12.31.81.21.72.41.71.21.71.6
Bone: cortical area3.14.811.42.73.4-2.82.82.72.82.92.71.72.42.81.3-0.8-1.8-2.1-1.20.0-1.3-2.3-0.7-0.5
Bone: cortical porosity1.71.92.91.11.1-1.71.11.41.21.31.11.61.51.11.6-1.5-1.5-1.3-1.7-1.3-1.3-1.2-1.4-1.4
Bone: cortical porosity2.72.94.41.61.3-1.91.51.71.51.71.52.11.91.52.1-2.0-1.9-1.5-2.0-1.8-1.6-1.4-1.7-1.6
Bone: cortical thickness1.11.98.20.82.9-0.90.91.91.00.90.9-0.61.21.0-1.21.6-0.4-1.9-0.32.4-0.6-2.50.40.6
Bone: cortical thickness0.60.73.60.51.6-0.30.31.00.60.00.5-0.50.50.3-0.91.0-0.2-1.00.11.5-0.2-1.90.50.5
Bone: cortical tissue density1.82.45.5-1.6-0.40.8-1.3-1.2-1.2-0.8-1.1-1.8-1.5-1.5-2.12.31.91.31.82.41.71.31.71.6
Condit. Reinf. active minus inactive responses0.10.10.5-0.5-0.70.5-0.4-0.5-0.5-0.5-0.6-0.2-0.4-0.4-0.1-0.00.20.3-0.1-0.20.1-0.1-0.1-0.2
Condit. Reinf. active-inactive response ratio0.30.30.9-0.7-0.9-0.1-0.4-0.8-0.7-0.4-0.6-0.0-0.5-0.50.1-0.00.40.80.2-0.20.61.0-0.0-0.3
Condit. Reinf. active responses0.50.61.6-1.0-1.21.3-1.0-0.8-1.2-1.2-1.2-0.8-0.7-0.9-0.60.30.40.30.00.00.1-0.30.0-0.3
Condit. Reinf. inactive responses0.50.72.5-0.8-1.01.6-0.9-0.7-1.0-1.2-1.1-1.1-0.8-0.9-0.90.60.50.20.30.40.1-0.50.30.1
Incentive salience index mean0.10.10.3-0.3-0.60.3-0.3-0.2-0.4-0.3-0.50.0-0.1-0.20.2-0.3-0.1-0.0-0.3-0.5-0.2-0.4-0.4-0.5
Condit. Reinf. lever presses0.10.20.7-0.5-0.60.8-0.5-0.4-0.6-0.7-0.6-0.4-0.4-0.5-0.30.20.20.20.2-0.00.0-0.40.1-0.1
Condit. Reinf. active minus inactive responses0.30.41.50.2-0.3-0.40.20.30.0-0.0-0.00.70.50.20.9-1.0-0.6-0.5-0.9-1.2-0.9-0.1-0.9-0.8
Condit. Reinf. active-inactive response ratio0.20.30.90.1-0.20.00.10.3-0.0-0.2-0.10.50.40.10.6-0.8-0.5-0.6-0.8-0.9-0.8-0.2-0.8-0.7
Condit. Reinf. active responses0.20.20.8-0.5-0.90.1-0.5-0.7-0.5-0.4-0.5-0.2-0.6-0.4-0.10.00.50.70.3-0.20.30.90.20.1
Condit. Reinf. inactive responses0.81.01.8-1.1-1.30.7-1.0-1.3-1.1-0.8-1.0-0.9-1.2-1.0-0.80.71.11.31.00.51.11.30.70.6
Condit. Reinf. lever presses1.01.42.7-1.3-1.61.1-1.2-1.7-1.3-0.9-1.2-0.9-1.5-1.1-0.80.71.21.61.10.41.21.50.80.5
Condit. Reinf. lever reinforcers received0.40.62.4-0.6-0.80.1-0.5-1.0-0.5-0.4-0.3-0.4-0.9-0.5-0.40.41.01.20.90.30.91.60.70.8
Conditioned reinforcement - actives0.71.23.3-0.30.00.4-0.4-0.8-0.1-0.4-0.0-1.1-1.0-0.5-1.31.41.41.21.61.61.40.71.71.8
Conditioned reinforcement - inactives0.00.00.20.20.3-0.20.10.30.10.10.1-0.00.2-0.1-0.10.1-0.1-0.3-0.10.2-0.4-0.5-0.0-0.0
Conditioned locomotion1.41.83.8-0.8-0.50.6-0.8-1.3-0.6-0.8-0.4-1.4-1.5-0.9-1.51.71.81.71.81.81.70.61.91.9
Patch foraging indifference point 0 sec0.91.72.8-1.2-1.41.3-1.0-1.7-1.2-0.9-1.1-1.3-1.6-0.9-1.31.21.51.61.71.01.40.81.31.2
Patch foraging indifference point AUC1.01.44.2-1.5-2.11.8-1.5-1.3-1.8-1.7-2.0-0.9-1.1-1.7-0.60.20.60.6-0.0-0.40.10.5-0.2-0.3
Delay disc. indifference point, 0s delay1.41.65.40.50.3-0.50.41.10.30.40.21.11.30.51.2-1.4-1.6-1.6-1.6-1.5-1.7-2.3-1.8-1.8
Delay disc. indifference point, 16s delay0.20.20.5-0.4-0.70.6-0.5-0.6-0.4-0.5-0.4-0.3-0.5-0.5-0.20.10.40.60.1-0.10.40.30.20.2
Delay disc. indifference point, 2s delay0.50.52.50.40.0-0.10.10.50.40.10.30.80.60.50.9-1.0-0.8-0.6-0.7-1.1-0.8-1.6-0.8-0.8
Delay disc. indifference point, 24s delay0.10.10.5-0.3-0.30.2-0.2-0.1-0.3-0.1-0.3-0.0-0.0-0.20.0-0.1-0.1-0.1-0.5-0.2-0.1-0.4-0.3-0.7
Delay disc. indifference point, 4s delay1.61.73.40.80.3-0.60.61.10.60.60.51.41.30.71.6-1.7-1.6-1.4-1.7-1.8-1.6-1.8-1.7-1.6
Delay disc. indifference point, 8s delay3.94.57.61.91.1-1.41.72.11.61.61.42.52.31.72.6-2.8-2.6-2.2-2.5-2.7-2.5-1.4-2.5-2.3
Indifference point function ln k0.50.93.70.41.5-0.80.50.30.90.71.0-0.5-0.10.7-0.91.30.60.41.21.91.0-0.11.41.4
Indifference point function log k0.50.93.70.41.5-0.80.50.30.90.71.0-0.5-0.10.7-0.91.30.60.41.21.91.0-0.11.41.4
Patch foraging total patch changes 0 sec1.22.23.7-1.4-1.51.4-1.1-1.8-1.3-1.1-1.3-1.6-1.8-1.1-1.51.51.81.91.91.21.70.91.61.4
Patch foraging total patch changes 12 sec3.03.97.3-2.2-2.52.7-2.1-2.3-2.4-2.3-2.4-2.2-2.2-2.1-1.91.61.91.71.61.01.41.01.31.2
Patch foraging total patch changes 18 sec1.92.96.9-1.7-2.62.3-1.7-2.3-1.9-1.8-1.9-1.4-2.1-1.8-1.00.71.72.01.40.11.52.01.00.9
Patch foraging total patch changes 24 sec0.30.52.20.3-0.80.00.5-0.0-0.10.2-0.20.60.20.30.9-1.2-0.6-0.2-0.8-1.5-0.7-1.1-0.9-0.9
Patch foraging total patch changes 6 sec1.62.53.5-1.8-1.81.8-1.7-1.8-1.9-1.5-1.8-1.7-1.8-1.8-1.61.51.71.41.41.11.30.91.11.1
Patch foraging time to switch 0 sec0.20.30.60.70.5-0.50.40.60.60.50.70.80.60.40.8-0.8-0.6-0.5-0.6-0.7-0.60.1-0.5-0.3
Patch foraging water rate 0 sec0.51.01.5-1.0-1.21.2-0.8-1.2-1.1-1.2-1.1-1.2-1.2-0.7-1.00.91.00.91.10.60.80.60.80.6
Patch foraging water rate 12 sec0.61.35.0-0.30.7-0.10.0-0.40.0-0.20.1-1.2-0.80.1-1.51.81.20.81.62.21.50.51.71.8
Patch foraging water rate 18 sec0.40.71.7-0.4-0.20.3-0.2-0.8-0.2-0.1-0.1-0.7-0.9-0.1-0.80.91.01.11.31.01.30.91.11.1
Patch foraging water rate 24 sec1.62.33.8-1.1-1.41.5-1.1-1.8-1.1-1.2-1.0-1.5-1.8-1.0-1.41.41.81.91.91.21.91.81.71.7
Patch foraging water rate 6 sec0.30.52.2-0.20.60.20.10.0-0.1-0.2-0.1-0.9-0.3-0.0-1.11.20.60.00.61.50.6-1.10.90.9
Seeking ratio, delayed vs. immediate footshock0.10.20.5-0.5-0.40.1-0.6-0.0-0.6-0.5-0.7-0.20.0-0.5-0.1-0.1-0.2-0.4-0.3-0.3-0.30.7-0.5-0.6
Distance traveled before self-admin0.40.51.30.40.2-0.30.30.70.40.20.30.70.80.40.8-0.9-0.9-1.0-1.0-1.0-1.2-1.0-0.9-0.8
Distance traveled after self-admin1.51.84.8-1.1-1.41.0-1.1-1.7-1.0-1.1-0.8-1.1-1.6-1.1-1.01.01.61.91.30.81.82.21.41.3
Extensor digitorum longus weight1.24.87.2-2.0-1.32.5-2.1-2.1-1.6-2.1-1.6-2.6-2.3-2.1-2.72.62.42.02.62.62.21.12.52.2
Bone: elastic displacement1.31.54.5-1.2-0.11.0-1.1-0.7-1.1-1.2-1.1-1.8-1.0-1.1-1.92.01.10.51.02.11.10.31.20.9
Bone: elastic work0.50.73.50.81.9-1.00.91.11.01.01.00.00.71.0-0.40.7-0.3-0.80.01.2-0.0-0.50.30.4
Bone: endosteal estimation1.12.45.42.00.3-2.01.90.12.02.02.22.20.62.12.3-2.1-0.90.9-0.0-2.00.20.6-0.3-0.5
Bone: endosteal perimeter4.28.917.23.51.7-3.63.42.03.43.73.44.12.63.54.2-3.9-2.9-1.0-2.1-3.6-1.6-0.9-2.1-2.3
Epididymis fat weight0.20.73.10.50.9-0.30.5-0.00.80.61.0-0.2-0.20.4-0.40.70.80.61.31.10.91.41.31.8
Delta time in closed arm before/after self-admin0.20.22.0-0.1-0.80.4-0.3-0.4-0.3-0.3-0.30.2-0.2-0.20.4-0.5-0.00.3-0.2-0.80.11.4-0.3-0.3
Delta time in open arm before/after self-admin0.80.71.3-1.1-0.81.0-1.1-0.8-1.0-1.1-1.1-1.0-0.8-1.2-1.00.90.70.50.70.70.50.40.40.4
Diff in mean of infusions in LGA sessions0.91.12.51.40.6-1.31.50.21.51.61.61.40.51.41.3-1.1-0.30.50.2-0.90.30.60.10.4
Delay discount exponential model param1.51.73.6-1.0-0.30.6-0.8-1.1-0.8-0.7-0.7-1.5-1.3-0.9-1.71.81.51.21.71.91.51.51.61.6
Extinction: sum of active levers before priming0.20.30.8-0.00.30.10.1-0.30.20.20.3-0.4-0.40.1-0.50.70.60.60.70.90.8-0.10.80.8
Active lever presses in extinction session 60.30.31.10.10.00.20.3-0.50.20.30.3-0.3-0.50.3-0.40.50.70.81.10.60.60.70.91.0
Bone: final force1.21.94.41.42.1-1.91.61.81.52.01.61.21.61.50.9-0.6-1.0-1.4-1.0-0.1-1.0-1.0-0.8-0.5
Bone: final moment1.32.14.91.52.2-2.01.81.91.62.11.71.31.71.71.0-0.6-1.1-1.5-1.1-0.1-1.0-1.2-0.8-0.6
Food consumed during 24 hour testing period0.40.62.4-0.3-1.00.5-0.3-0.1-0.6-0.1-0.60.50.2-0.30.8-1.0-0.6-0.3-1.0-1.4-0.7-0.1-1.1-1.5
Glucose0.50.83.11.21.8-1.00.91.21.41.01.40.61.00.70.3-0.1-0.4-0.8-0.00.4-0.4-0.20.10.6
Heart weight0.81.35.31.42.3-1.01.21.41.61.41.60.21.01.2-0.20.5-0.3-1.00.21.2-0.2-1.10.51.1
Delay discount hyperbolic model param1.51.73.5-1.0-0.40.6-0.7-1.1-0.8-0.7-0.7-1.5-1.3-0.9-1.71.81.51.21.71.91.51.61.61.5
Intermittent access intake day 1-15 change0.30.61.40.50.2-0.20.20.80.20.20.10.70.90.10.8-0.9-1.0-1.1-1.1-1.0-1.2-0.5-1.1-1.0
Intermittent access intake escalation0.20.41.10.20.2-0.3-0.00.70.00.0-0.10.40.7-0.10.5-0.6-0.8-1.0-0.9-0.6-1.0-0.5-1.0-0.9
Intermittent access intake escalation 20.20.20.70.30.1-0.00.00.50.20.10.10.40.5-0.00.5-0.6-0.7-0.7-0.6-0.6-0.8-0.1-0.7-0.5
Intermitt. access day 1 inactive lever presses0.10.61.70.80.6-1.30.90.60.80.90.80.90.70.60.9-0.8-0.7-0.4-0.7-0.7-0.8-0.5-0.5-0.4
Intermitt. access day 15 inactive lever presses0.10.20.5-0.5-0.70.6-0.6-0.6-0.5-0.6-0.6-0.4-0.6-0.7-0.30.20.40.60.40.10.20.00.30.3
Intermitt. access escalation Index0.40.51.70.2-0.2-0.30.30.40.10.20.00.80.60.31.0-1.1-0.9-0.6-0.8-1.3-0.70.2-1.1-1.3
Intermittent access day 1 total infusions0.61.03.70.51.0-0.70.7-0.20.80.71.0-0.4-0.40.5-0.71.11.00.91.41.51.20.71.61.9
Intermittent access day 15 total infusions0.00.10.3-0.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.3-0.2-0.3-0.40.50.30.10.30.50.20.20.30.4
Intermittent access terminal intake (last 3 days)0.10.20.60.60.6-0.80.60.40.70.60.70.30.30.40.3-0.1-0.1-0.00.10.1-0.1-0.00.20.5
Intermittent access total infusions0.30.41.10.60.9-0.90.80.20.80.80.90.00.00.5-0.20.50.40.40.70.80.50.20.81.0
Intermittent access day 1 locomotion1.01.32.8-0.7-0.40.2-0.5-1.1-0.4-0.4-0.3-1.1-1.2-0.7-1.21.41.51.51.51.51.51.11.71.6
Intermittent access day 15 total locomotion0.10.20.90.20.5-0.40.20.00.40.20.4-0.3-0.20.1-0.50.60.40.30.70.80.30.20.81.0
Intermittent access total locomotion0.50.62.1-0.00.3-0.40.1-0.40.20.20.3-0.6-0.6-0.1-0.81.01.00.91.11.31.00.51.31.4
Intermittent access standard deviation3.06.210.63.33.1-2.83.12.93.23.13.22.72.72.92.4-2.1-2.2-2.2-1.7-1.4-1.9-1.1-1.3-0.4
Left kidney weight1.04.68.52.72.9-2.22.82.62.72.92.72.22.52.61.9-1.6-1.9-2.1-1.4-0.9-1.7-0.8-1.2-0.6
Right kidney weight0.31.24.11.42.0-1.11.41.51.61.61.60.71.21.30.4-0.2-0.7-1.1-0.30.4-0.6-0.7-0.10.2
Cocaine induced anxiety0.50.72.40.20.5-0.20.21.00.10.2-0.00.50.90.10.5-0.6-1.1-1.4-1.5-0.6-1.2-1.4-1.2-1.2
Post-drug Anxiety0.20.21.3-0.10.40.3-0.20.5-0.1-0.2-0.1-0.20.3-0.0-0.30.2-0.3-0.8-0.80.3-0.5-1.1-0.2-0.1
Baseline Anxiety0.50.51.4-0.3-0.30.2-0.2-0.8-0.1-0.20.1-0.5-0.8-0.1-0.60.71.01.21.20.71.10.61.21.2
Tail length0.10.51.8-0.2-1.01.1-0.3-0.1-0.5-0.6-0.60.30.1-0.30.5-0.9-0.6-0.4-0.7-1.3-0.8-0.0-1.0-1.2
Length with tail1.04.15.62.41.7-1.52.32.22.02.12.02.22.32.22.2-2.2-2.2-2.1-1.8-2.0-2.2-1.3-1.9-1.6
Length without tail2.16.712.03.33.5-3.13.43.13.33.13.32.52.83.32.2-1.8-2.2-2.4-1.4-1.0-1.9-1.7-1.2-0.6
Times rat made contact with spout0.30.30.8-0.8-0.90.9-0.8-0.7-0.7-0.6-0.7-0.4-0.6-0.8-0.30.20.40.60.2-0.00.40.10.2-0.0
Lifetime Intake0.40.51.20.71.0-1.00.90.20.91.01.00.10.10.7-0.10.50.40.40.70.90.50.20.91.1
Liver weight, left1.22.03.91.71.7-1.71.71.51.72.01.71.51.51.71.4-1.1-1.3-1.1-1.0-0.7-0.9-1.5-0.8-0.6
Liver weight, right0.91.62.61.41.0-1.21.21.21.31.21.31.61.31.11.6-1.6-1.3-1.0-1.2-1.4-1.3-1.1-1.1-1.1
Locomotor activity0.10.11.5-0.3-0.2-0.1-0.2-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.20.30.20.30.10.30.3-1.20.2-0.3
Locomotor testing distance0.10.21.0-0.2-0.3-0.4-0.1-0.6-0.00.10.1-0.0-0.5-0.2-0.10.20.61.00.60.20.90.60.60.3
Locomotor testing rearing0.61.32.6-1.5-1.60.8-1.5-1.5-1.5-1.4-1.4-1.0-1.3-1.5-0.80.71.01.30.60.30.9-0.40.5-0.1
Locomotion in novel chamber0.50.73.0-0.9-1.70.9-0.9-1.1-1.0-0.9-1.0-0.1-0.8-1.00.2-0.40.20.9-0.2-0.90.30.7-0.3-0.6
Locomotion in novel chamber post-restriction0.30.51.70.5-0.3-0.80.6-0.00.40.70.51.00.30.51.1-1.1-0.30.3-0.4-1.2-0.21.3-0.6-0.6
Fecal boli incidents, locomotor time 10.50.72.2-0.1-0.1-0.0-0.1-0.80.2-0.00.3-0.5-0.9-0.1-0.70.91.11.41.31.01.40.71.41.5
Change in fecal boli incidents, locomotor task0.00.00.20.00.30.10.00.10.10.00.1-0.2-0.0-0.0-0.30.30.2-0.00.10.40.2-0.50.30.3
Time >=10cm from walls, locomotor time 10.30.31.3-0.2-0.6-0.1-0.1-0.1-0.3-0.0-0.30.60.2-0.20.7-0.9-0.5-0.1-0.7-1.1-0.40.5-0.9-1.1
Bouts of movement, locomotor time 10.10.10.6-0.10.4-0.0-0.20.10.1-0.4-0.0-0.4-0.1-0.0-0.50.60.2-0.10.10.70.1-0.80.50.4
Total resting periods, locomotor time 10.20.20.7-0.20.30.1-0.3-0.1-0.0-0.5-0.1-0.6-0.2-0.3-0.60.70.40.10.30.80.3-0.40.60.6
Rest time, locomotor task time 10.50.62.30.91.5-1.01.00.81.10.91.20.20.50.8-0.10.3-0.0-0.30.10.80.10.00.61.0
Distance moved, locomotor task time 10.30.41.3-0.7-1.10.8-0.7-0.4-0.9-0.5-1.0-0.1-0.2-0.60.1-0.4-0.2-0.0-0.3-0.8-0.40.5-0.7-0.9
Vertical activity count, locomotor time 10.51.23.4-1.3-1.81.8-1.7-1.3-1.5-1.6-1.5-1.0-1.2-1.2-0.70.40.70.80.4-0.10.40.30.2-0.0
Time >=10cm from walls, locomotor time 20.20.30.8-0.9-0.40.6-0.8-0.2-0.8-0.7-0.8-0.6-0.3-0.8-0.50.50.2-0.1-0.30.40.00.1-0.1-0.4
Bouts of movement, locomotor time 20.10.21.20.60.5-0.60.60.30.70.60.70.50.30.40.4-0.3-0.10.10.1-0.10.11.10.10.4
Total resting periods, locomotor time 20.20.31.20.60.5-0.70.70.20.70.60.80.50.20.40.4-0.3-0.10.20.1-0.10.21.10.20.4
Rest time, locomotor task time 20.60.82.41.21.0-1.41.40.51.41.11.61.00.51.10.8-0.6-0.10.30.0-0.30.30.00.40.9
Distance moved, locomotor task time 20.30.41.1-0.9-0.40.9-0.9-0.1-0.9-0.6-1.0-0.8-0.2-0.6-0.70.6-0.0-0.5-0.20.4-0.4-0.6-0.3-0.7
Vertical activity count, locomotor time 20.20.30.7-0.4-0.20.9-0.7-0.3-0.4-0.6-0.4-0.8-0.5-0.2-0.80.70.50.10.50.70.2-0.60.60.4
Light reinforcement 11.53.66.0-2.1-2.12.5-2.0-2.1-2.1-2.2-2.2-2.2-2.1-2.0-2.01.81.81.61.61.31.31.41.41.4
Light reinforcement 20.10.21.2-0.4-0.71.1-0.3-0.2-0.7-0.7-0.8-0.5-0.3-0.3-0.40.10.0-0.20.1-0.1-0.30.5-0.20.1
Bone: marrow area1.12.45.42.00.3-2.01.90.12.01.92.12.20.62.12.3-2.1-0.90.9-0.0-2.00.20.6-0.3-0.5
Bone: maximum diameter6.812.720.34.43.6-4.54.33.44.34.54.44.23.64.44.0-3.5-3.4-2.3-2.5-2.7-2.2-2.3-2.2-2.0
Bone: maximum force1.22.15.41.82.3-2.12.01.71.92.22.11.41.51.90.9-0.5-0.8-1.0-0.50.1-0.5-0.5-0.3-0.0
Bone: maximum moment1.32.45.91.82.4-2.32.21.82.02.32.11.41.62.01.0-0.6-0.9-1.0-0.60.1-0.5-0.7-0.4-0.1
Mean time between licks in bursts0.00.00.1-0.10.2-0.3-0.10.30.00.30.00.10.2-0.20.1-0.0-0.1-0.3-0.20.0-0.1-0.2-0.3-0.4
Mean num. licks in bursts0.40.71.1-0.9-0.80.8-0.7-1.0-0.8-0.8-0.7-0.8-1.0-0.8-0.80.71.01.00.60.61.00.80.70.6
Cd content in liver1.51.63.2-0.9-0.40.7-0.7-1.2-0.7-1.0-0.7-1.5-1.3-0.7-1.61.71.61.41.61.81.60.91.71.6
Co content in liver0.00.00.3-0.10.1-0.20.1-0.1-0.10.1-0.1-0.2-0.10.2-0.20.30.10.1-0.10.40.2-0.50.20.1
Cu content in liver0.20.21.80.30.2-0.20.50.30.20.30.20.30.30.40.3-0.3-0.4-0.3-0.4-0.3-0.3-1.3-0.4-0.5
Fe content in liver0.20.31.10.0-0.80.40.2-0.4-0.2-0.2-0.20.5-0.10.30.7-0.8-0.40.3-0.4-1.0-0.1-0.5-0.5-0.9
K content in liver0.40.41.3-0.9-1.00.4-0.7-0.6-1.1-0.8-1.1-0.3-0.4-0.7-0.20.00.10.2-0.4-0.3-0.0-0.3-0.4-0.7
Mg content in liver2.22.34.1-2.0-1.91.3-1.9-1.8-2.0-1.8-2.0-1.4-1.6-1.9-1.31.11.41.51.00.71.21.20.70.3
Mn content in liver0.30.30.90.10.1-0.10.10.4-0.10.0-0.10.40.50.10.4-0.5-0.6-0.6-1.0-0.6-0.6-1.0-0.8-1.0
Na content in liver0.20.20.9-0.3-0.5-0.5-0.1-0.1-0.40.3-0.40.30.1-0.20.3-0.4-0.3-0.0-0.6-0.5-0.2-0.3-0.7-0.9
Rb content in liver1.51.72.9-1.6-1.41.4-1.7-1.4-1.5-1.5-1.4-1.4-1.4-1.6-1.41.21.41.21.20.91.10.90.90.7
Se content in liver0.91.03.1-1.4-1.71.2-1.2-1.3-1.5-1.4-1.6-0.7-1.0-1.2-0.50.30.50.90.2-0.20.5-0.1-0.0-0.5
Sr content in liver0.10.10.6-0.10.5-0.30.10.10.10.10.0-0.3-0.00.1-0.40.60.30.00.40.80.30.40.40.5
Zn content in liver0.10.10.90.50.4-0.40.50.30.40.30.40.10.20.40.1-0.1-0.2-0.20.10.1-0.1-1.00.00.0
Bone: minimum diameter2.74.99.42.61.8-3.12.71.82.52.82.52.72.12.72.6-2.4-2.2-1.2-1.6-2.0-1.3-0.9-1.5-1.8
Time in familiar zone, hab. session 10.10.10.2-0.2-0.20.2-0.3-0.2-0.2-0.4-0.2-0.3-0.2-0.3-0.30.30.20.10.10.20.1-0.10.30.4
Time in novel zone, hab. session 10.50.51.30.30.2-0.60.40.60.20.30.20.80.70.40.8-0.8-0.8-0.7-1.0-0.8-0.8-0.4-1.0-1.1
Total zone transitions, hab. session 11.72.33.9-2.0-1.51.8-1.7-1.6-1.9-1.4-1.9-1.7-1.6-1.8-1.71.61.51.41.11.31.40.90.90.5
Total locomotion distance, hab. session 11.52.23.1-1.7-1.41.7-1.6-1.5-1.7-1.5-1.7-1.7-1.6-1.6-1.71.61.51.21.41.31.20.71.10.7
Locomotion velocity, hab. session 12.12.94.3-2.0-1.52.0-1.8-1.8-1.9-1.6-1.8-2.1-1.9-1.8-2.01.91.81.51.81.71.60.81.41.0
Time in familiar zone, hab. session 20.10.10.7-0.0-0.00.0-0.0-0.3-0.00.10.0-0.3-0.30.0-0.40.40.40.40.30.50.40.40.60.8
Time in novel zone, hab. session 20.30.30.80.40.4-0.80.40.60.40.40.40.80.70.40.8-0.7-0.7-0.5-0.5-0.7-0.50.0-0.8-0.9
Total zone transitions, hab. session 25.57.08.8-2.9-2.42.6-2.8-2.9-2.7-2.5-2.6-2.9-3.0-2.6-2.92.82.92.82.42.42.82.22.31.8
Total locomotion distance, hab. session 25.67.39.9-2.8-2.22.7-2.7-2.8-2.6-2.8-2.5-3.1-3.0-2.6-3.13.02.92.52.72.72.72.02.52.1
Locomotion velocity, hab. session 25.57.310.2-2.9-2.32.9-2.7-2.8-2.8-2.9-2.7-3.2-3.0-2.6-3.23.02.92.52.62.72.51.82.41.9
Novel to familiar place preference ratio2.12.33.7-1.5-1.31.0-1.3-1.8-1.3-1.2-1.2-1.5-1.8-1.3-1.61.61.81.91.71.51.91.51.61.2
Novelty place preference1.61.72.9-1.3-1.10.9-1.1-1.6-1.1-1.0-1.0-1.3-1.5-1.1-1.31.31.61.71.51.21.71.41.41.1
Time in novel zone, NPP test2.02.13.3-1.4-1.21.0-1.3-1.7-1.3-1.2-1.2-1.5-1.7-1.3-1.51.51.71.81.61.31.81.51.51.2
Total zone transitions, NPP test3.44.96.8-2.6-2.22.6-2.3-2.4-2.6-2.2-2.5-2.6-2.5-2.2-2.52.32.32.01.81.92.01.21.71.2
Total locomotion distance, NPP test6.89.313.8-3.2-2.53.3-3.0-3.1-3.0-3.0-3.0-3.7-3.3-2.9-3.73.53.32.73.23.22.81.62.82.3
Locomotion velocity, NPP test5.78.112.0-3.0-2.33.1-2.8-2.9-2.8-2.8-2.8-3.5-3.1-2.7-3.43.33.12.53.02.92.71.52.62.1
Intraocular pressure0.91.35.7-0.1-0.80.9-0.2-1.40.0-0.20.1-0.5-1.3-0.2-0.50.51.31.91.90.41.52.41.51.7
Delta distance traveled before/after self-admin2.42.55.5-1.4-1.21.2-1.2-1.8-1.2-1.1-1.1-1.5-1.8-1.4-1.61.71.92.01.61.52.12.31.71.5
Delta ambulatory time before/after self-admin2.42.96.8-1.5-1.41.2-1.3-2.0-1.4-1.2-1.3-1.6-1.9-1.5-1.61.72.02.21.81.52.22.61.71.5
Parametrial fat weight0.00.10.40.30.1-0.00.2-0.20.40.30.4-0.0-0.20.4-0.00.10.30.40.60.20.20.10.50.6
Pavlov. Cond. lever latency0.50.65.7-0.4-0.90.4-0.5-1.0-0.3-0.3-0.2-0.1-0.8-0.5-0.10.10.71.30.8-0.10.92.40.60.7
Pavlov. Cond. magazine entry latency2.53.24.11.61.2-1.91.71.81.41.51.32.01.91.72.0-2.0-2.0-1.8-2.0-1.8-1.9-1.9-1.9-1.9
Pavlov. Cond. change in total contacts0.40.51.8-0.50.3-0.0-0.4-0.3-0.3-0.4-0.3-0.8-0.5-0.5-1.01.20.80.40.71.40.7-0.60.80.8
Pavlov. Cond. index score1.31.63.81.21.2-1.31.31.51.01.10.91.21.41.31.1-1.1-1.3-1.5-1.3-0.9-1.4-2.0-1.2-1.1
Pavlov. Cond. latency score1.82.25.81.41.4-1.41.51.71.21.21.11.31.71.51.3-1.2-1.6-1.8-1.5-1.0-1.7-2.4-1.4-1.3
Pavlov. Cond. lever contacts0.20.22.70.20.7-0.20.30.60.20.00.1-0.10.40.3-0.20.2-0.2-0.7-0.30.4-0.4-1.7-0.2-0.2
Pavlov. Cond. magazine entry number2.53.14.1-1.8-1.62.0-1.9-1.9-1.7-1.7-1.6-1.9-2.0-1.9-1.91.71.91.81.71.51.81.61.61.4
Pavlov. Cond. intertrial magazine entries1.92.33.6-1.8-1.71.6-1.9-1.8-1.6-1.6-1.6-1.5-1.7-1.9-1.41.31.51.61.31.01.41.41.10.9
Pavlov. Cond. lever-magazine prob. diff.0.91.12.90.91.0-1.11.01.20.80.90.70.91.21.00.9-0.8-1.1-1.2-1.1-0.7-1.1-1.7-1.0-1.0
Pavlov. Cond. response bias1.31.72.81.31.3-1.51.41.51.21.31.11.31.51.41.2-1.1-1.3-1.4-1.3-0.8-1.3-1.7-1.1-1.0
Pavlov. Cond. lever latency0.81.02.71.01.6-0.81.11.51.00.71.00.61.31.00.4-0.3-0.9-1.6-0.90.0-1.1-1.4-0.6-0.1
Pavlov. Cond. magazine entry latency0.70.82.6-0.1-0.10.1-0.2-0.80.20.00.3-0.6-0.9-0.2-0.70.91.11.31.61.01.31.41.51.5
Pavlov. Cond. change in total contacts1.01.63.5-0.9-1.10.7-1.1-1.6-0.7-0.8-0.6-1.0-1.5-1.1-1.01.01.51.91.80.91.61.71.51.3
Pavlov. Cond. index score0.71.02.5-0.6-0.90.5-0.9-1.3-0.5-0.4-0.4-0.7-1.2-0.8-0.70.71.11.61.50.61.31.41.20.9
Pavlov. Cond. latency score0.40.61.8-0.4-0.80.3-0.6-1.1-0.3-0.2-0.2-0.4-1.0-0.5-0.40.40.91.31.20.31.11.30.90.7
Pavlov. Cond. lever contacts1.21.63.6-1.3-1.91.3-1.4-1.8-1.3-1.0-1.2-0.9-1.6-1.3-0.80.61.21.81.30.21.31.60.90.4
Pavlov. Cond. magazine entry number0.60.71.90.30.5-0.40.51.00.10.20.10.71.00.40.7-0.7-1.0-1.3-1.4-0.8-1.2-1.3-1.3-1.2
Pavlov. Cond. intertrial magazine entries0.50.72.7-0.6-1.60.7-0.5-0.7-1.0-0.5-1.00.3-0.3-0.40.6-1.0-0.40.3-0.7-1.5-0.40.2-1.0-1.5
Pavlov. Cond. lever-magazine prob. diff.0.70.92.4-0.6-0.90.5-0.8-1.3-0.4-0.4-0.3-0.6-1.2-0.8-0.60.61.11.61.40.51.31.51.10.9
Pavlov. Cond. response bias1.21.73.3-1.0-1.31.1-1.1-1.7-0.9-0.8-0.8-1.2-1.6-1.1-1.11.11.51.81.70.91.61.61.41.2
Time in closed arm before self-admin0.10.20.80.20.9-0.20.30.60.30.30.3-0.20.40.2-0.40.5-0.1-0.60.00.7-0.3-0.70.10.4
Time in closed arm after self-admin0.60.71.51.11.2-1.21.20.91.21.21.20.70.81.10.5-0.3-0.4-0.5-0.6-0.0-0.10.50.00.3
Time in open arm before self-admin0.10.10.3-0.0-0.2-0.20.1-0.0-0.10.1-0.10.30.10.10.4-0.4-0.20.0-0.4-0.4-0.20.2-0.3-0.6
Time in open arm after self-admin0.70.81.6-1.0-1.10.9-1.0-1.1-1.0-1.0-0.9-0.7-1.0-1.0-0.60.50.71.00.90.30.71.30.50.3
Bone: periosteal estimation2.55.310.73.12.4-3.13.01.93.13.23.22.72.03.32.5-2.1-1.9-0.8-0.9-1.5-0.8-1.2-0.8-0.8
Bone: periosteal perimeter6.511.217.74.03.6-4.04.03.53.94.23.83.73.54.13.4-3.0-3.3-2.7-2.5-2.2-2.4-2.7-2.2-2.1
Bone: post-yield work0.40.61.6-0.5-0.3-0.1-0.4-0.9-0.2-0.1-0.1-0.5-0.8-0.5-0.60.81.01.31.20.91.31.31.00.9
Progressive ratio test 1 active lever presses0.40.51.2-0.2-0.10.1-0.1-0.6-0.1-0.10.0-0.5-0.7-0.2-0.60.70.81.01.10.80.91.11.01.0
Progressive ratio test 1 breakpoint0.40.41.2-0.2-0.10.1-0.1-0.6-0.1-0.00.0-0.5-0.7-0.2-0.60.70.81.01.00.80.91.11.00.9
Progressive ratio test 1 inactive lever presses0.00.00.10.2-0.0-0.30.20.00.20.20.20.20.10.00.2-0.2-0.10.1-0.1-0.2-0.3-0.2-0.1-0.0
Progressive ratio test 2 active lever presses0.80.92.4-0.4-0.00.1-0.3-0.7-0.2-0.2-0.1-0.9-0.9-0.4-1.11.21.11.11.61.41.11.41.41.3
Progressive ratio test 2 breakpoint0.70.82.1-0.40.1-0.0-0.2-0.6-0.1-0.2-0.0-0.8-0.8-0.3-1.01.21.00.91.51.31.01.31.31.3
Progressive ratio test 2 inactive lever presses0.00.10.30.20.4-0.20.10.20.20.20.2-0.20.0-0.0-0.30.40.1-0.00.40.50.00.30.40.5
Incentive Sensitization - Responses0.20.30.90.60.9-0.90.70.60.80.70.80.30.50.60.10.0-0.2-0.40.20.3-0.4-0.20.10.3
Incentive Sensitization - Breakpoint0.30.41.00.71.0-1.00.80.70.90.80.90.40.60.70.2-0.0-0.3-0.50.20.3-0.5-0.20.10.2
Sum of active levers in priming session hrs 5-60.40.31.00.40.6-0.70.6-0.10.70.60.80.2-0.10.40.00.20.40.70.70.50.70.60.81.0
Progressive ratio0.50.72.70.60.8-0.70.6-0.10.80.50.9-0.2-0.30.7-0.40.80.80.81.11.21.10.51.41.7
Food seeking constrained by brief footshock0.81.02.31.41.5-1.41.11.21.41.11.40.91.11.40.8-0.5-0.5-0.8-0.3-0.2-0.6-0.7-0.20.2
Seeking ratio, punishment vs. effort0.40.61.60.20.1-0.10.10.70.10.2-0.00.70.80.10.8-0.9-0.9-1.0-1.0-1.1-1.1-0.9-1.2-1.3
Retroperitoneal fat weight0.00.10.50.2-0.50.20.1-0.40.20.20.30.3-0.30.10.4-0.50.20.60.5-0.60.10.70.20.4
Reaction time number correct1.93.76.8-2.2-2.62.4-2.2-2.5-2.2-2.1-2.1-1.8-2.3-2.1-1.51.21.82.21.60.71.61.71.20.8
Reaction time mean minus median0.20.62.00.81.0-0.50.81.00.70.80.60.40.90.60.4-0.3-0.7-1.0-0.7-0.1-1.0-1.4-0.5-0.3
Reaction time mean minus median AUC0.51.33.90.90.8-0.70.91.20.70.90.60.91.20.81.0-1.0-1.3-1.5-1.5-1.0-1.5-2.0-1.3-1.2
Reaction time num false alarms0.10.10.30.3-0.0-0.30.2-0.20.2-0.00.3-0.1-0.20.2-0.10.10.30.30.50.10.30.60.50.4
Reaction time num false alarms AUC0.20.21.20.0-0.3-0.10.0-0.50.0-0.20.1-0.3-0.50.0-0.30.30.60.70.90.30.61.10.70.7
Reaction time trials correct on left1.93.76.8-2.2-2.62.4-2.2-2.5-2.2-2.1-2.1-1.8-2.3-2.1-1.51.21.82.21.60.71.61.71.20.8
Reaction time trials on left1.93.66.7-2.1-2.62.4-2.2-2.4-2.2-2.1-2.1-1.7-2.2-2.0-1.51.21.72.11.60.61.61.71.20.8
Reaction time mean0.00.00.30.00.3-0.10.00.20.10.10.2-0.00.1-0.1-0.10.2-0.0-0.1-0.10.30.0-0.50.10.0
Reaction time mean AUC0.00.10.3-0.10.30.1-0.1-0.00.10.00.1-0.2-0.1-0.2-0.30.40.20.10.10.60.3-0.40.40.3
Median of all reaction times0.00.00.1-0.10.2-0.1-0.20.00.1-0.00.1-0.0-0.0-0.2-0.10.20.10.1-0.10.30.2-0.40.20.0
Reaction time omissions1.11.54.51.41.0-0.71.41.31.21.41.11.11.21.41.1-1.1-1.3-1.3-1.1-1.0-1.2-2.1-1.0-0.8
Reaction time false alarm rate0.40.51.81.01.0-1.31.10.81.00.81.00.60.71.00.5-0.4-0.4-0.5-0.1-0.2-0.30.1-0.00.0
Reaction time premature initiation rate3.14.37.4-2.2-1.11.7-1.9-1.9-1.9-1.8-1.8-2.5-2.1-2.1-2.62.72.41.92.12.72.31.02.11.8
Reaction time premature initiations4.68.210.3-3.1-2.42.7-2.8-3.1-2.7-2.7-2.6-3.1-3.2-2.9-3.23.13.23.13.02.83.22.12.72.3
Std. dev. reaction times0.10.11.20.20.50.00.20.30.20.30.2-0.10.20.1-0.10.2-0.1-0.3-0.20.3-0.3-1.10.10.0
Reaction time trials completed1.93.66.7-2.1-2.62.4-2.2-2.4-2.2-2.1-2.1-1.7-2.2-2.0-1.51.21.72.11.60.61.61.71.20.8
Reaction time trials AUC2.34.47.7-2.4-2.82.6-2.4-2.7-2.4-2.3-2.3-2.0-2.5-2.3-1.71.42.02.31.80.91.81.91.41.0
Run reversals in cocaine runway, females0.20.20.70.80.50.10.40.50.80.30.80.50.40.70.5-0.5-0.4-0.30.2-0.4-0.4-0.50.00.3
Run reversals in cocaine runway, males0.50.52.20.61.0-0.50.30.20.70.30.8-0.3-0.10.5-0.60.80.70.30.71.10.60.21.01.5
Latency to leave start box in cocaine runway0.40.41.3-0.20.10.1-0.2-0.4-0.1-0.20.0-0.7-0.6-0.1-0.90.90.80.61.01.00.80.81.01.1
Latency to leave start box in cocaine runway, F0.60.61.7-0.6-0.50.5-0.7-0.8-0.6-0.7-0.5-0.9-0.8-0.5-0.90.90.90.80.90.80.81.30.91.0
Latency to leave start box in cocaine runway, M0.30.31.10.10.4-0.20.3-0.20.20.30.4-0.4-0.40.1-0.70.80.60.50.91.00.8-0.30.90.8
Std. dev. time between licks in bursts1.31.84.0-1.6-2.01.8-1.6-1.7-1.7-1.6-1.7-1.2-1.5-1.5-1.00.81.11.40.60.31.01.00.60.1
Total sessions with >9 infusions1.31.64.41.61.9-1.81.90.81.91.92.10.70.61.70.40.10.10.30.60.80.4-0.01.01.4
Short access day 1 total inactive lever presses1.21.63.31.51.3-1.71.71.21.51.81.51.41.31.41.3-1.0-1.0-0.7-1.0-0.7-1.0-1.0-0.7-0.5
Short access day 10 total inactive lever presses0.61.43.40.5-0.1-0.70.50.80.20.50.11.31.10.41.5-1.6-1.4-1.1-1.7-1.8-1.7-1.2-1.7-1.8
Short access day 1 total infusions0.91.23.21.41.6-1.51.80.81.61.81.80.80.71.50.5-0.1-0.1-0.00.30.40.0-0.10.50.7
Short access day 10 total infusions1.21.54.31.71.4-1.92.00.61.92.02.11.20.71.71.0-0.6-0.20.30.4-0.10.20.30.50.9
Short access total infusions0.70.92.31.11.3-1.31.40.41.41.41.50.40.31.20.20.20.30.50.70.70.50.30.91.2
Short access day 1 locomotion0.50.61.60.91.3-1.11.30.51.11.31.20.40.40.90.10.20.10.10.30.60.3-0.30.60.8
Short access day 10 total locomotion0.40.71.91.11.1-1.31.30.71.31.31.40.80.61.10.6-0.3-0.3-0.1-0.10.0-0.1-0.40.20.5
Short access total locomotion1.31.64.01.72.0-2.01.91.21.91.92.01.01.01.70.6-0.2-0.4-0.4-0.10.4-0.2-0.80.40.7
One hour access (0.3 mA shock)0.70.92.3-0.3-0.10.4-0.3-0.7-0.1-0.30.0-0.8-0.9-0.4-1.01.11.21.11.41.31.21.11.41.5
Compulsive drug intake0.40.40.8-0.7-0.70.8-0.7-0.7-0.7-0.7-0.6-0.7-0.7-0.6-0.60.60.60.70.50.40.30.90.50.4
One hour access (shock baseline)0.00.10.40.30.3-0.10.2-0.00.30.20.3-0.0-0.10.1-0.10.20.20.20.40.30.30.10.40.6
Social response proportion0.30.30.8-0.2-0.00.8-0.4-0.4-0.1-0.5-0.2-0.7-0.5-0.3-0.80.80.60.40.70.90.5-0.20.90.8
Social responses0.20.20.9-0.5-0.20.9-0.5-0.1-0.6-0.5-0.6-0.5-0.2-0.6-0.50.40.1-0.3-0.20.3-0.2-0.7-0.1-0.2
Social time0.30.41.1-0.3-0.00.7-0.5-0.3-0.3-0.5-0.3-0.9-0.5-0.3-0.91.00.60.30.81.00.50.30.80.7
Soleus weight0.51.43.0-1.2-0.41.7-1.3-0.7-1.1-1.2-1.1-1.7-1.0-1.3-1.71.71.00.30.91.70.7-0.31.01.0
Bone: stiffness1.11.84.31.62.1-1.81.61.71.71.71.81.31.61.51.0-0.7-1.0-1.3-0.9-0.2-0.9-1.1-0.7-0.3
Tibialis anterior weight0.20.72.1-0.70.10.9-0.6-0.4-0.4-0.4-0.4-1.1-0.7-0.7-1.21.30.90.50.81.50.8-0.11.01.0
Time to tail flick, vehicle, before self-admin0.30.31.1-0.7-0.40.7-0.8-0.2-0.7-0.8-0.8-0.6-0.3-0.7-0.60.60.2-0.1-0.00.5-0.2-1.0-0.0-0.3
Time to tail flick, vehicle, after self-admin1.01.33.41.41.8-1.51.41.51.51.41.50.91.31.30.7-0.5-1.0-1.3-0.3-0.1-0.90.7-0.40.2
Time to tail flick, test, before self-admin0.80.82.2-1.3-1.51.2-1.3-1.0-1.3-1.3-1.3-0.7-0.9-1.2-0.40.20.50.60.0-0.20.3-0.3-0.1-0.5
Time to tail flick, test, after self-admin1.81.92.61.61.4-1.31.51.51.51.41.51.61.61.51.5-1.4-1.5-1.3-0.9-1.2-1.4-0.3-1.1-0.9
Delta time to tail flick, vehicle, before/after SA0.70.71.81.00.8-1.11.00.71.11.01.00.90.71.00.9-0.8-0.5-0.4-0.1-0.6-0.41.3-0.20.1
Delta time to tail flick, test, before/after SA2.72.84.72.12.2-1.92.02.12.02.01.91.62.02.01.4-1.3-1.7-1.9-1.0-0.8-1.6-0.7-1.1-0.6
Tibia length12.033.044.06.35.5-5.35.86.65.85.85.66.16.65.85.9-5.8-6.2-6.3-5.6-4.9-5.9-4.9-5.1-4.0
Ambulatory time before self-admin0.91.33.40.90.7-0.60.71.30.80.50.71.01.30.91.1-1.2-1.3-1.5-1.4-1.2-1.6-1.8-1.2-1.0
Ambulatory time after self-admin0.70.92.6-0.8-0.90.6-0.6-1.2-0.7-0.6-0.6-0.7-1.1-0.7-0.70.81.11.30.80.61.21.61.01.0
Bone: tissue strength0.70.72.3-0.6-0.0-0.1-0.1-0.6-0.40.0-0.3-0.7-0.7-0.3-0.91.11.11.01.01.21.11.50.90.9
Total heroin consumption2.12.44.81.91.6-2.12.11.42.02.22.01.91.52.01.8-1.5-1.3-0.7-0.6-1.1-0.60.1-0.8-0.5
Bone: trabecular number0.20.41.0-0.9-1.00.3-0.9-0.7-0.9-0.7-0.8-0.2-0.5-1.0-0.10.10.30.60.0-0.20.30.8-0.1-0.4
Bone: trabecular spacing0.20.31.10.80.50.10.80.40.70.50.60.30.40.80.3-0.3-0.3-0.4-0.1-0.2-0.3-1.10.00.3
Bone: trabecular thickness0.30.41.1-0.8-0.60.1-0.8-0.8-0.6-0.3-0.5-0.4-0.7-0.8-0.40.50.51.00.60.40.91.00.4-0.1
Bone: trabecular tissue density0.20.21.60.50.10.40.60.40.20.20.10.10.30.60.2-0.4-0.5-0.7-0.2-0.4-0.8-1.3-0.4-0.2
Water consumed over 24 hours0.30.41.2-0.8-1.01.1-0.8-0.5-1.0-0.7-1.0-0.5-0.4-0.9-0.30.10.10.0-0.3-0.2-0.20.2-0.3-0.6
Number of responses in last shaping day1.41.53.31.61.8-1.71.71.31.71.81.71.11.21.40.9-0.6-0.8-0.8-0.3-0.1-0.7-1.5-0.20.0