Hub : Genes

Dleu7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Dleu7 0.45 0.04 0.0e+00 0.49 0.55 0.54 0.54 1.3e-51 3.6e-61 1.4e-58 4.4e-60
2 NAcc gene expression Dleu7 0.68 0.07 0.0e+00 0.58 0.62 0.62 0.62 4.0e-110 1.5e-120 9.4e-123 4.2e-121
3 BLA gene expression Dleu7 0.67 0.09 0.0e+00 0.52 0.51 0.54 0.54 4.8e-32 3.9e-31 2.8e-33 1.4e-33
4 RMTg gene expression Dleu7 0.54 0.16 1.7e-12 0.35 0.37 0.3 0.39 3.6e-10 7.2e-11 1.5e-08 3.1e-11
5 pVTA gene expression Dleu7 0.62 0.09 0.0e+00 0.52 0.59 0.6 0.6 3.0e-48 9.2e-59 2.7e-59 5.9e-60
6 IL gene expression Dleu7 0.44 0.16 1.8e-06 0.14 0.15 0.13 0.14 3.3e-04 1.7e-04 6.0e-04 3.7e-04
7 IC gene expression Dleu7 0.62 0.12 0.0e+00 0.36 0.42 0.43 0.44 4.5e-16 2.8e-19 1.7e-19 2.9e-20
8 LHb gene expression Dleu7 0.5 0.13 9.9e-11 0.3 0.27 0.3 0.29 5.9e-08 3.8e-07 8.5e-08 1.5e-07
9 PL gene expression Dleu7 0.56 0.11 0.0e+00 0.42 0.51 0.51 0.52 4.8e-50 3.3e-64 9.0e-64 1.8e-65
10 Eye gene expression Dleu7 0.29 0.16 6.7e-03 0.02 0.1 0.07 0.07 1.5e-01 1.2e-02 3.6e-02 3.0e-02
11 OFC gene expression Dleu7 0.69 0.15 3.3e-09 0.23 0.2 0.22 0.22 3.2e-06 1.3e-05 6.0e-06 6.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.30.61.00.9-0.80.90.80.60.70.9-0.51.00.2-0.7
Area under the delay curve2.23.36.5-2.21.5-1.7-1.9-1.2-2.5-2.01.9-2.3-1.01.1
BMI with tail1.34.67.1-2.02.7-2.5-2.1-2.7-1.2-2.02.2-1.7-2.51.8
BMI without tail0.10.61.9-0.51.3-0.8-0.6-1.40.0-0.50.3-0.3-1.10.3
Body weight1.35.87.9-2.52.8-2.6-2.4-2.6-2.4-2.62.4-2.5-2.20.9
Weight adjusted by age0.82.33.6-1.51.4-1.6-1.6-1.5-1.2-1.31.5-1.2-1.91.9
Bone surface0.50.92.00.9-0.91.10.90.80.60.9-0.81.00.9-1.4
Bone volume0.40.81.80.9-0.91.00.80.70.40.9-0.61.00.7-1.4
Breakpoint value in progressive ratio session0.40.81.1-1.01.0-0.9-0.9-0.8-1.0-1.00.8-1.0-0.80.5
Number of licking bursts0.00.10.4-0.30.4-0.4-0.5-0.6-0.10.00.5-0.0-0.50.1
Context. condit. distance diff. score0.30.30.80.9-0.70.50.80.90.50.4-0.30.30.1-0.1
Locomotion velocity, session 12.02.32.9-1.61.7-1.6-1.5-1.6-1.2-1.51.2-1.4-1.51.6
Locomotion distance, session 11.01.31.9-1.31.1-1.1-1.4-1.2-1.1-1.01.2-0.9-1.11.2
Locomotion velocity, session 20.10.10.5-0.20.0-0.3-0.4-0.1-0.7-0.20.7-0.1-0.60.1
Locomotion distance, session 20.10.10.30.2-0.20.2-0.1-0.0-0.10.40.30.4-0.50.0
Locomotion velocity, session 30.91.13.4-0.50.7-1.0-1.0-0.8-0.7-0.61.3-0.6-1.81.5
Locomotion distance, session 30.80.92.3-0.70.8-0.8-1.0-0.8-0.9-0.71.0-0.7-1.51.2
Stereotopy head waving bouts, day 30.91.01.41.2-1.21.01.01.11.01.1-0.71.00.9-1.0
Stereotopy head waving duration, day 30.00.10.2-0.30.2-0.3-0.3-0.2-0.2-0.20.5-0.2-0.1-0.1
Locomotion velocity, session 70.50.51.21.1-0.50.40.50.20.81.0-0.51.0-0.90.5
Locomotion distance, session 72.32.94.62.1-2.11.81.61.71.82.1-1.62.00.7-0.4
Stereotopy head waving bouts, day 73.13.74.7-1.82.1-2.2-1.8-1.9-1.6-1.92.0-1.8-1.91.8
Stereotopy head waving duration, day 74.04.96.4-2.12.3-2.4-2.2-2.1-2.1-2.12.5-2.1-2.32.0
Locomotion velocity, session 80.20.21.0-0.1-0.3-0.0-0.20.4-1.0-0.40.7-0.5-0.3-0.2
Locomotion distance, session 80.10.10.30.3-0.40.10.10.4-0.20.10.4-0.0-0.60.5
Degree of sensitization distance6.67.18.62.8-2.82.72.62.42.92.9-2.72.82.4-2.0
Degree of sensitization stereotypy3.84.35.1-2.12.2-2.2-2.0-1.8-2.1-2.32.0-2.3-1.82.0
Conditioned locomotion1.21.44.91.1-1.91.31.22.20.00.6-0.60.21.20.1
Cocaine response after cond. corrected0.30.51.50.6-0.50.60.80.70.30.4-0.60.40.8-1.2
Cocaine response after cond. not corrected0.30.41.20.4-0.50.60.60.70.20.4-0.60.30.9-1.1
Cocaine response before conditioning0.70.91.8-1.10.8-0.9-1.1-0.9-0.8-0.90.6-0.9-0.81.3
Saline control response0.20.31.2-0.3-0.40.10.20.7-0.5-0.5-0.4-0.71.1-0.4
Bone: connectivity density0.61.01.61.3-1.21.11.21.11.01.0-1.01.00.6-0.3
Bone: cortical apparent density1.21.82.8-1.31.6-1.6-1.3-1.7-0.7-1.31.3-1.1-1.51.3
Bone: cortical area0.00.00.20.10.10.00.1-0.10.00.1-0.00.2-0.0-0.5
Bone: cortical porosity1.31.43.8-1.20.6-0.9-1.1-0.2-2.0-1.41.1-1.5-0.71.2
Bone: cortical porosity1.51.74.5-1.40.6-1.1-1.2-0.1-2.1-1.61.1-1.8-0.71.3
Bone: cortical thickness0.30.50.8-0.80.9-0.8-0.8-0.8-0.6-0.80.7-0.7-0.80.4
Bone: cortical thickness1.21.52.3-1.11.2-1.3-1.2-1.1-1.1-1.21.2-1.1-1.51.4
Bone: cortical tissue density1.11.82.7-1.31.6-1.6-1.3-1.6-0.6-1.21.3-1.1-1.51.2
Condit. Reinf. active minus inactive responses2.32.64.0-1.71.9-1.7-1.7-2.0-1.0-1.51.3-1.3-1.71.6
Condit. Reinf. active-inactive response ratio0.20.20.7-0.30.7-0.4-0.4-0.80.3-0.10.10.1-0.60.4
Condit. Reinf. active responses3.74.86.0-2.42.3-2.2-2.3-2.3-1.7-2.31.6-2.2-2.22.5
Condit. Reinf. inactive responses1.92.54.2-1.91.2-1.4-1.6-1.0-1.8-2.01.2-2.0-1.01.6
Incentive salience index mean4.25.46.7-2.52.6-2.4-2.4-2.6-1.7-2.31.9-2.1-2.42.5
Condit. Reinf. lever presses4.97.310.0-2.92.8-2.8-2.8-2.9-2.0-2.72.3-2.5-2.73.2
Condit. Reinf. active minus inactive responses0.50.82.8-0.91.0-0.9-0.8-1.0-0.2-0.80.2-0.8-0.81.7
Condit. Reinf. active-inactive response ratio0.81.23.7-0.81.2-1.2-0.9-1.3-0.0-0.70.7-0.6-1.51.9
Condit. Reinf. active responses0.91.23.0-1.21.1-1.1-1.1-1.1-0.6-1.10.7-1.1-0.91.7
Condit. Reinf. inactive responses0.20.31.30.2-0.70.70.50.80.10.3-0.6-0.01.1-0.3
Condit. Reinf. lever presses4.36.37.5-2.62.7-2.6-2.7-2.7-1.8-2.32.6-2.1-2.62.7
Condit. Reinf. lever reinforcers received1.31.93.7-1.61.4-1.4-1.4-1.4-0.8-1.40.9-1.4-1.11.9
Conditioned reinforcement - actives1.76.69.92.5-3.02.82.62.82.72.2-3.12.02.7-1.1
Conditioned reinforcement - inactives2.87.69.93.1-3.02.92.82.72.92.9-2.72.92.2-2.0
Conditioned locomotion1.72.54.11.4-1.91.71.62.01.41.2-2.00.91.9-0.9
Patch foraging indifference point 0 sec0.30.73.90.3-0.70.80.40.7-0.20.3-0.20.31.3-2.0
Patch foraging indifference point AUC0.10.30.90.60.00.10.2-0.40.90.80.40.9-0.5-0.3
Delay disc. indifference point, 0s delay0.10.10.4-0.3-0.1-0.1-0.10.3-0.7-0.40.4-0.70.10.1
Delay disc. indifference point, 16s delay0.50.82.8-1.20.2-0.4-0.80.1-1.7-1.00.8-1.30.30.0
Delay disc. indifference point, 2s delay1.71.82.9-1.51.1-1.3-1.3-0.8-1.7-1.51.5-1.7-0.91.2
Delay disc. indifference point, 24s delay0.30.51.2-1.10.7-0.7-0.9-0.6-1.0-0.70.7-0.6-0.20.2
Delay disc. indifference point, 4s delay3.73.96.1-2.21.7-1.9-1.8-1.3-2.4-2.31.9-2.5-1.61.8
Delay disc. indifference point, 8s delay1.32.24.3-1.81.3-1.4-1.6-1.1-2.1-1.61.7-1.7-0.70.5
Indifference point function ln k0.10.41.3-0.90.3-0.4-0.50.0-1.1-1.10.1-1.00.20.2
Indifference point function log k0.10.41.3-0.90.3-0.4-0.50.0-1.1-1.10.1-1.00.20.2
Patch foraging total patch changes 0 sec0.20.53.2-0.2-0.40.4-0.10.4-0.7-0.20.3-0.11.0-1.8
Patch foraging total patch changes 12 sec0.40.51.3-0.70.7-0.5-0.8-1.0-0.5-0.21.10.0-0.4-0.8
Patch foraging total patch changes 18 sec0.10.20.8-0.30.0-0.0-0.3-0.1-0.5-0.10.7-0.00.2-0.9
Patch foraging total patch changes 24 sec0.20.52.7-0.70.2-0.3-0.8-0.3-1.0-0.51.7-0.4-0.2-0.4
Patch foraging total patch changes 6 sec0.10.21.40.10.10.2-0.0-0.30.30.40.30.50.3-1.2
Patch foraging time to switch 0 sec0.10.30.70.5-0.80.40.50.80.20.5-0.30.30.30.7
Patch foraging water rate 0 sec0.31.12.0-1.31.1-0.9-1.1-0.9-1.4-1.40.8-1.2-0.5-0.4
Patch foraging water rate 12 sec1.14.48.1-2.61.8-2.0-2.2-1.3-2.9-2.71.7-2.7-1.11.0
Patch foraging water rate 18 sec3.37.39.6-3.12.8-2.6-3.0-2.5-3.1-3.02.6-2.8-2.31.3
Patch foraging water rate 24 sec1.01.53.5-1.50.9-0.9-1.3-0.5-1.9-1.70.8-1.8-0.30.3
Patch foraging water rate 6 sec2.13.16.7-2.21.3-1.6-1.9-1.0-2.6-2.31.7-2.3-0.70.5
Seeking ratio, delayed vs. immediate footshock1.11.53.21.2-1.31.21.51.80.80.5-1.70.31.6-0.6
Distance traveled before self-admin0.10.30.7-0.40.0-0.5-0.40.2-0.7-0.80.6-0.8-0.30.8
Distance traveled after self-admin0.10.20.90.1-0.60.30.41.0-0.2-0.2-0.5-0.50.60.2
Extensor digitorum longus weight6.124.232.0-5.24.5-5.2-5.2-4.0-5.7-5.35.5-5.1-4.43.7
Bone: elastic displacement0.60.81.80.6-1.21.00.81.3-0.00.5-0.60.31.3-1.0
Bone: elastic work0.10.20.6-0.4-0.1-0.1-0.30.2-0.8-0.40.6-0.40.3-0.5
Bone: endosteal estimation0.71.72.31.5-1.41.41.41.31.11.4-1.21.31.0-1.2
Bone: endosteal perimeter1.12.83.51.8-1.81.91.91.81.41.6-1.61.51.5-1.3
Epididymis fat weight0.10.62.5-0.4-0.2-0.40.10.9-1.1-1.20.2-1.60.40.4
Delta time in closed arm before/after self-admin0.00.00.20.10.1-0.30.10.0-0.1-0.20.4-0.2-0.0-0.2
Delta time in open arm before/after self-admin1.41.72.91.4-0.81.41.20.51.71.6-1.41.70.7-1.0
Diff in mean of infusions in LGA sessions0.10.10.6-0.1-0.20.2-0.30.1-0.7-0.20.8-0.2-0.1-0.5
Delay discount exponential model param3.44.78.02.6-1.92.12.31.62.82.4-2.32.61.4-1.4
Extinction: sum of active levers before priming0.10.20.3-0.50.0-0.2-0.5-0.0-0.5-0.30.5-0.4-0.30.6
Active lever presses in extinction session 60.10.10.2-0.1-0.40.1-0.20.4-0.3-0.10.3-0.10.10.3
Bone: final force0.50.81.7-0.90.4-0.9-0.9-0.3-1.2-1.01.3-1.0-0.70.6
Bone: final moment0.71.12.1-1.00.6-1.0-1.0-0.4-1.4-1.21.5-1.2-0.80.7
Food consumed during 24 hour testing period0.10.20.5-0.50.7-0.7-0.5-0.7-0.3-0.40.3-0.3-0.50.2
Glucose0.20.31.0-0.20.6-0.3-0.5-1.00.20.10.60.4-0.9-0.2
Heart weight0.30.40.8-0.80.9-0.7-0.8-0.9-0.3-0.50.1-0.4-0.60.8
Delay discount hyperbolic model param3.24.27.32.4-1.82.02.11.42.72.3-2.12.51.3-1.4
Intermittent access intake day 1-15 change0.31.92.81.5-1.71.51.31.51.21.4-1.01.31.3-1.2
Intermittent access intake escalation0.21.31.81.3-1.41.21.11.30.91.2-0.71.01.1-1.1
Intermittent access intake escalation 20.50.91.51.1-0.91.00.90.80.91.2-0.61.10.6-0.9
Intermitt. access day 1 inactive lever presses0.78.512.43.2-2.73.02.72.13.43.4-2.93.52.3-2.5
Intermitt. access day 15 inactive lever presses0.42.23.11.7-1.61.61.61.51.51.6-1.51.51.1-0.8
Intermitt. access escalation Index0.10.31.0-0.40.6-0.3-0.7-1.00.10.30.50.5-0.5-0.1
Intermittent access day 1 total infusions0.51.53.01.1-1.71.41.11.61.00.8-1.10.81.5-0.9
Intermittent access day 15 total infusions1.63.96.82.1-2.62.21.92.41.71.9-1.61.71.9-1.4
Intermittent access terminal intake (last 3 days)2.54.47.02.4-2.62.32.02.32.12.2-1.62.11.7-1.5
Intermittent access total infusions4.35.18.22.3-2.92.52.22.62.12.1-2.02.02.3-1.7
Intermittent access day 1 locomotion0.30.51.00.5-1.00.80.60.90.50.5-0.70.60.8-0.7
Intermittent access day 15 total locomotion0.93.45.21.7-2.32.01.62.01.31.9-1.21.81.9-2.2
Intermittent access total locomotion1.51.82.91.3-1.71.51.31.61.21.3-1.21.21.4-1.3
Intermittent access standard deviation0.21.12.60.8-1.61.20.91.60.20.7-0.70.51.5-1.0
Left kidney weight1.08.211.5-2.83.2-3.0-3.0-3.3-2.2-2.62.7-2.4-3.42.7
Right kidney weight2.315.720.4-4.14.5-4.3-4.1-4.5-3.2-3.83.7-3.6-4.23.4
Cocaine induced anxiety0.41.12.1-1.10.7-0.9-0.9-0.3-1.3-1.40.9-1.5-0.61.3
Post-drug Anxiety0.20.20.7-0.2-0.1-0.2-0.10.4-0.5-0.60.2-0.7-0.10.8
Baseline Anxiety0.10.10.40.40.00.10.2-0.20.60.5-0.40.5-0.20.2
Tail length0.00.20.7-0.60.4-0.3-0.3-0.2-0.8-0.70.1-0.7-0.1-0.2
Length with tail0.10.31.4-0.2-0.10.1-0.00.4-0.9-0.40.1-0.50.5-1.2
Length without tail0.21.33.0-1.30.8-1.0-1.1-0.6-1.7-1.31.5-1.4-0.4-0.3
Times rat made contact with spout0.20.20.5-0.40.2-0.2-0.5-0.3-0.6-0.10.6-0.0-0.2-0.7
Lifetime Intake4.15.18.02.3-2.82.52.32.62.22.1-2.11.92.3-1.6
Liver weight, left2.74.68.0-2.82.3-2.1-2.4-2.2-2.2-2.32.1-2.2-1.31.2
Liver weight, right0.20.30.8-0.70.6-0.3-0.4-0.6-0.7-0.50.1-0.50.3-0.9
Locomotor activity2.74.18.5-2.41.9-1.9-2.2-1.5-2.9-2.42.1-2.4-1.30.5
Locomotor testing distance0.10.31.1-0.40.1-0.1-0.20.2-1.0-0.60.1-0.70.6-1.1
Locomotor testing rearing0.10.41.1-0.70.8-0.4-0.6-0.7-0.6-0.40.2-0.30.3-1.0
Locomotion in novel chamber1.82.42.9-1.61.7-1.7-1.4-1.3-1.7-1.61.5-1.6-1.41.4
Locomotion in novel chamber post-restriction0.10.30.90.6-0.90.40.50.9-0.30.3-0.00.2-0.00.4
Fecal boli incidents, locomotor time 11.02.64.4-1.82.0-1.8-1.8-2.1-1.4-1.41.7-1.2-1.40.3
Change in fecal boli incidents, locomotor task1.92.03.41.8-1.91.71.51.81.01.5-1.01.21.0-0.6
Time >=10cm from walls, locomotor time 10.20.20.9-0.20.1-0.4-0.2-0.0-0.4-0.40.5-0.7-0.50.9
Bouts of movement, locomotor time 10.30.40.9-0.51.0-0.8-0.6-0.9-0.6-0.50.6-0.2-0.80.1
Total resting periods, locomotor time 10.30.30.9-0.40.9-0.7-0.5-0.9-0.5-0.30.6-0.1-0.7-0.1
Rest time, locomotor task time 11.52.56.5-1.42.1-1.7-1.8-2.6-0.8-0.81.6-0.4-2.00.6
Distance moved, locomotor task time 10.61.63.71.2-1.71.31.41.90.80.8-1.30.51.6-0.5
Vertical activity count, locomotor time 10.32.15.70.9-2.01.51.32.4-0.20.5-1.20.02.3-1.3
Time >=10cm from walls, locomotor time 20.10.20.70.5-0.80.50.40.90.00.20.0-0.10.10.5
Bouts of movement, locomotor time 20.00.10.3-0.30.6-0.3-0.2-0.6-0.2-0.10.10.2-0.2-0.4
Total resting periods, locomotor time 20.10.31.0-0.50.9-0.6-0.5-1.0-0.3-0.20.50.1-0.6-0.3
Rest time, locomotor task time 21.62.86.6-1.82.1-1.6-2.0-2.6-1.0-1.01.7-0.5-2.00.7
Distance moved, locomotor task time 20.40.51.70.2-0.90.60.51.3-0.2-0.2-0.4-0.51.20.1
Vertical activity count, locomotor time 20.51.13.70.2-1.30.70.91.8-0.4-0.3-1.0-0.91.9-0.3
Light reinforcement 10.10.51.5-0.70.4-0.7-0.8-0.2-1.2-0.70.9-0.9-0.50.2
Light reinforcement 20.61.22.41.1-1.31.11.31.50.60.8-1.40.41.3-0.9
Bone: marrow area0.81.92.41.6-1.41.51.51.41.21.4-1.31.31.1-1.2
Bone: maximum diameter0.91.82.61.4-1.31.51.51.30.91.3-1.31.21.3-1.6
Bone: maximum force0.30.61.8-0.70.1-0.6-0.70.1-1.3-0.91.3-1.0-0.30.3
Bone: maximum moment0.50.92.3-1.00.4-0.8-0.9-0.2-1.5-1.21.5-1.2-0.50.5
Mean time between licks in bursts0.10.41.10.6-0.20.50.5-0.11.00.8-0.61.00.3-0.6
Mean num. licks in bursts0.00.10.4-0.30.10.1-0.10.0-0.5-0.3-0.1-0.20.3-0.6
Cd content in liver0.40.51.6-0.80.9-0.5-0.7-1.0-0.7-0.30.4-0.00.1-1.3
Co content in liver0.30.41.3-0.70.1-0.4-0.7-0.2-1.1-0.41.0-0.4-0.1-0.6
Cu content in liver1.72.04.2-1.11.4-1.5-1.5-1.6-0.9-0.91.7-0.7-2.01.7
Fe content in liver0.60.71.70.9-0.80.70.90.81.10.8-1.30.80.50.0
K content in liver0.60.61.91.1-1.40.70.81.30.50.60.10.40.10.4
Mg content in liver2.02.23.71.8-1.91.61.61.71.31.5-1.11.31.2-1.0
Mn content in liver1.31.52.91.2-1.71.21.21.60.91.0-0.70.71.4-1.1
Na content in liver2.22.55.5-1.31.0-1.5-1.4-0.8-1.4-1.61.9-1.8-1.72.3
Rb content in liver3.74.35.52.0-2.42.22.12.21.62.0-1.81.72.3-2.3
Se content in liver2.53.03.91.6-1.81.91.71.81.21.6-2.01.42.0-1.8
Sr content in liver0.50.51.30.60.10.40.4-0.41.11.0-0.71.1-0.1-0.5
Zn content in liver0.40.52.50.3-0.50.70.20.20.20.70.10.80.8-1.6
Bone: minimum diameter0.30.61.40.8-0.70.80.80.70.50.8-0.70.80.6-1.2
Time in familiar zone, hab. session 10.40.50.8-0.80.6-0.7-0.7-0.5-0.5-0.80.5-0.8-0.50.9
Time in novel zone, hab. session 10.70.81.91.0-0.81.00.80.70.51.0-0.51.00.7-1.4
Total zone transitions, hab. session 10.50.71.2-0.80.7-0.8-1.0-0.8-0.8-0.61.1-0.6-0.91.0
Total locomotion distance, hab. session 10.10.10.50.0-0.30.0-0.20.2-0.30.10.7-0.0-0.10.1
Locomotion velocity, hab. session 10.20.20.7-0.4-0.1-0.3-0.50.1-0.7-0.40.9-0.6-0.20.6
Time in familiar zone, hab. session 20.50.51.80.3-0.80.60.71.2-0.00.0-0.9-0.21.3-0.6
Time in novel zone, hab. session 20.30.31.1-0.00.6-0.4-0.4-0.80.10.10.70.3-1.00.3
Total zone transitions, hab. session 21.82.34.0-1.61.0-1.3-1.7-1.0-1.9-1.52.0-1.5-1.31.4
Total locomotion distance, hab. session 20.70.92.7-0.90.2-0.6-1.0-0.2-1.6-0.81.7-0.9-0.60.5
Locomotion velocity, hab. session 20.81.13.0-1.10.4-0.7-1.3-0.4-1.7-0.91.7-1.0-0.80.6
Novel to familiar place preference ratio1.31.62.61.6-1.31.41.31.11.41.5-1.21.50.7-0.5
Novelty place preference1.21.52.61.6-1.31.41.31.11.41.5-1.11.50.6-0.5
Time in novel zone, NPP test1.21.42.41.5-1.21.31.21.01.31.4-1.11.40.5-0.4
Total zone transitions, NPP test1.01.42.2-1.31.1-1.1-1.4-1.1-1.3-1.11.5-1.0-1.11.0
Total locomotion distance, NPP test0.10.20.60.2-0.30.4-0.1-0.10.30.70.30.80.0-0.5
Locomotion velocity, NPP test0.10.20.60.2-0.30.3-0.2-0.20.20.70.50.8-0.1-0.4
Intraocular pressure1.32.15.81.1-1.21.51.51.31.41.1-2.41.01.9-1.1
Delta distance traveled before/after self-admin1.31.42.91.1-0.81.21.20.81.41.2-1.71.21.2-1.0
Delta ambulatory time before/after self-admin0.61.11.70.9-1.01.10.90.91.01.1-1.30.91.2-1.0
Parametrial fat weight1.73.96.41.7-2.12.31.92.21.21.5-2.11.32.3-2.5
Pavlov. Cond. lever latency2.43.05.01.9-2.11.81.82.20.91.5-1.01.41.7-2.1
Pavlov. Cond. magazine entry latency0.20.20.6-0.50.7-0.4-0.3-0.70.2-0.4-0.2-0.3-0.10.8
Pavlov. Cond. change in total contacts1.11.12.3-1.51.5-1.1-1.1-1.5-0.8-1.10.5-1.0-0.40.4
Pavlov. Cond. index score2.83.65.6-2.22.4-2.0-2.0-2.4-1.3-1.81.2-1.6-1.72.0
Pavlov. Cond. latency score2.73.45.6-2.12.3-2.0-1.9-2.4-1.1-1.71.1-1.5-1.62.1
Pavlov. Cond. lever contacts2.02.44.1-1.71.9-1.6-1.6-2.0-0.8-1.40.9-1.2-1.51.9
Pavlov. Cond. magazine entry number1.41.82.91.6-1.71.41.41.70.91.4-0.91.21.0-1.3
Pavlov. Cond. intertrial magazine entries1.61.92.6-1.51.2-1.5-1.4-1.1-1.4-1.61.3-1.6-1.31.4
Pavlov. Cond. lever-magazine prob. diff.2.83.45.4-2.12.3-2.0-1.9-2.3-1.2-1.71.3-1.5-1.71.8
Pavlov. Cond. response bias2.02.53.5-1.81.9-1.6-1.7-1.9-1.1-1.61.1-1.4-1.41.9
Pavlov. Cond. lever latency3.65.16.62.4-2.32.42.42.41.82.1-2.61.92.3-2.0
Pavlov. Cond. magazine entry latency1.62.33.8-1.61.4-1.6-1.4-1.0-1.7-1.91.3-1.9-1.11.6
Pavlov. Cond. change in total contacts2.35.77.6-2.62.3-2.5-2.6-2.2-2.4-2.42.8-2.3-2.11.9
Pavlov. Cond. index score3.55.56.9-2.62.4-2.5-2.5-2.2-2.3-2.42.5-2.4-2.02.0
Pavlov. Cond. latency score3.45.56.8-2.62.4-2.5-2.4-2.1-2.2-2.52.4-2.4-2.02.1
Pavlov. Cond. lever contacts3.55.27.2-2.42.3-2.4-2.4-2.3-2.0-2.22.7-2.0-2.31.9
Pavlov. Cond. magazine entry number1.92.53.11.7-1.61.71.61.41.61.7-1.51.81.3-1.4
Pavlov. Cond. intertrial magazine entries1.43.15.21.8-1.21.81.60.72.32.2-1.92.31.2-1.6
Pavlov. Cond. lever-magazine prob. diff.3.55.36.8-2.62.3-2.4-2.4-2.1-2.2-2.52.4-2.4-1.92.0
Pavlov. Cond. response bias4.15.76.6-2.62.4-2.5-2.5-2.3-2.2-2.42.6-2.3-2.22.2
Time in closed arm before self-admin0.30.40.9-0.60.4-0.6-0.7-0.5-0.8-0.60.9-0.5-0.90.7
Time in closed arm after self-admin1.51.72.6-1.31.2-1.5-1.2-1.0-1.6-1.61.6-1.4-0.90.6
Time in open arm before self-admin0.30.41.2-0.50.1-0.5-0.20.4-1.0-1.00.3-1.10.10.4
Time in open arm after self-admin0.70.71.61.1-0.60.90.80.31.31.1-0.81.20.1-0.4
Bone: periosteal estimation0.51.31.71.3-1.01.21.20.91.01.2-1.11.20.8-1.3
Bone: periosteal perimeter0.40.81.01.0-0.71.00.90.70.81.0-0.91.00.7-0.9
Bone: post-yield work0.10.20.40.2-0.60.50.20.5-0.20.30.20.30.5-0.6
Progressive ratio test 1 active lever presses0.71.32.11.1-1.41.21.11.11.41.0-1.21.11.0-0.6
Progressive ratio test 1 breakpoint0.71.11.71.0-1.31.11.01.01.31.0-1.11.11.0-0.7
Progressive ratio test 1 inactive lever presses1.02.64.11.6-1.71.71.41.31.71.9-1.42.01.4-1.6
Progressive ratio test 2 active lever presses1.92.75.82.0-1.61.51.51.02.41.9-1.42.20.8-0.9
Progressive ratio test 2 breakpoint1.82.34.91.8-1.41.41.41.02.21.8-1.22.00.7-0.8
Progressive ratio test 2 inactive lever presses1.03.37.02.2-1.61.71.71.02.72.1-1.72.41.0-1.0
Incentive Sensitization - Responses0.51.33.71.6-0.70.81.10.41.91.4-0.91.60.2-0.5
Incentive Sensitization - Breakpoint0.51.23.31.6-0.70.81.10.41.81.4-0.91.60.2-0.5
Sum of active levers in priming session hrs 5-60.10.10.20.2-0.10.20.10.10.50.5-0.40.4-0.10.1
Progressive ratio0.10.30.6-0.60.6-0.4-0.4-0.4-0.8-0.70.4-0.6-0.1-0.1
Food seeking constrained by brief footshock0.40.51.80.4-0.10.60.50.00.70.6-0.70.80.8-1.3
Seeking ratio, punishment vs. effort0.00.00.10.0-0.30.2-0.00.10.30.3-0.10.2-0.00.2
Retroperitoneal fat weight0.00.10.50.4-0.10.10.40.40.1-0.1-0.2-0.30.4-0.7
Reaction time number correct0.00.10.30.2-0.10.20.1-0.10.50.5-0.30.60.2-0.4
Reaction time mean minus median0.00.31.3-0.40.3-0.4-0.20.0-0.4-0.60.2-0.8-0.21.1
Reaction time mean minus median AUC0.00.21.0-0.20.7-0.5-0.2-0.50.2-0.30.2-0.3-0.51.0
Reaction time num false alarms0.10.20.7-0.30.2-0.5-0.5-0.3-0.5-0.40.8-0.3-0.80.4
Reaction time num false alarms AUC0.20.61.4-0.50.5-0.8-0.8-0.6-0.7-0.61.1-0.5-1.20.6
Reaction time trials correct on left0.00.10.30.2-0.10.20.1-0.10.50.5-0.30.60.2-0.4
Reaction time trials on left0.00.20.40.3-0.10.20.1-0.10.60.6-0.40.70.3-0.5
Reaction time mean0.20.40.80.5-0.70.70.70.90.40.3-0.90.10.60.4
Reaction time mean AUC0.20.40.90.5-0.70.70.70.90.40.3-1.00.10.70.4
Median of all reaction times0.30.51.30.6-0.90.90.81.00.50.5-1.10.30.70.1
Reaction time omissions1.21.94.31.6-0.61.11.40.42.11.8-1.61.70.9-1.2
Reaction time false alarm rate0.40.61.5-0.50.6-0.8-0.7-0.6-0.8-0.71.1-0.6-1.20.6
Reaction time premature initiation rate0.30.41.0-0.4-0.1-0.5-0.50.3-0.8-0.80.8-1.0-0.51.0
Reaction time premature initiations0.00.10.3-0.1-0.3-0.2-0.20.4-0.3-0.30.3-0.4-0.20.6
Std. dev. reaction times0.10.20.40.5-0.40.50.50.60.60.3-0.50.20.30.6
Reaction time trials completed0.00.20.40.3-0.10.20.1-0.10.60.6-0.40.70.3-0.5
Reaction time trials AUC0.10.20.50.3-0.20.30.20.10.60.6-0.40.70.4-0.6
Run reversals in cocaine runway, females0.91.02.31.2-1.00.61.41.50.90.5-1.40.10.80.2
Run reversals in cocaine runway, males1.21.32.5-1.31.1-1.1-1.1-0.8-1.2-1.61.1-1.6-0.61.0
Latency to leave start box in cocaine runway0.70.91.41.1-0.60.81.10.61.21.1-1.21.00.7-1.0
Latency to leave start box in cocaine runway, F1.62.02.51.5-1.11.41.41.01.51.5-1.61.51.2-1.5
Latency to leave start box in cocaine runway, M0.30.30.8-0.30.9-0.8-0.3-0.8-0.2-0.40.4-0.4-0.80.4
Std. dev. time between licks in bursts1.12.13.21.5-1.71.61.61.71.41.3-1.41.11.8-1.0
Total sessions with >9 infusions1.92.43.31.4-1.81.71.51.61.71.3-1.81.21.6-1.0
Short access day 1 total inactive lever presses0.10.10.70.0-0.40.2-0.10.20.10.1-0.10.1-0.30.8
Short access day 10 total inactive lever presses0.00.31.20.20.20.30.1-0.50.60.7-0.50.90.4-1.1
Short access day 1 total infusions2.24.36.92.0-2.62.32.12.32.01.9-2.21.72.1-1.1
Short access day 10 total infusions0.61.02.20.7-1.51.10.91.50.60.3-1.00.21.4-0.7
Short access total infusions2.13.05.11.6-2.31.91.72.11.61.3-1.81.12.1-1.3
Short access day 1 locomotion0.20.30.50.2-0.70.70.40.40.60.4-0.70.40.7-0.7
Short access day 10 total locomotion0.20.61.1-1.01.0-0.9-0.8-0.9-0.4-0.90.4-0.9-0.50.5
Short access total locomotion0.00.10.3-0.50.1-0.1-0.3-0.30.1-0.3-0.2-0.20.00.1
One hour access (0.3 mA shock)1.61.92.71.2-1.21.41.21.01.61.5-1.51.61.5-1.3
Compulsive drug intake1.52.25.5-1.52.3-1.7-1.5-2.2-1.0-1.11.0-0.9-1.50.9
One hour access (shock baseline)2.05.28.82.2-3.02.52.22.71.92.1-2.01.92.5-1.8
Social response proportion2.12.64.31.9-1.51.61.81.42.01.8-2.11.61.0-0.5
Social responses1.01.22.61.1-0.81.11.10.81.41.2-1.61.11.1-0.6
Social time0.60.92.5-0.61.2-1.0-0.9-1.5-0.3-0.10.80.1-1.60.7
Soleus weight0.61.82.5-1.61.5-1.5-1.4-1.5-1.2-1.51.2-1.3-0.90.5
Bone: stiffness0.10.10.6-0.10.1-0.2-0.3-0.2-0.5-0.10.8-0.1-0.4-0.2
Tibialis anterior weight6.321.728.1-4.84.7-5.0-5.0-4.3-5.2-4.65.3-4.4-4.43.1
Time to tail flick, vehicle, before self-admin0.20.31.20.4-0.80.00.51.10.1-0.2-0.1-0.40.30.6
Time to tail flick, vehicle, after self-admin0.10.31.40.5-0.40.40.40.5-0.20.30.30.40.3-1.2
Time to tail flick, test, before self-admin0.60.61.1-0.60.9-0.9-0.7-0.8-0.6-0.91.0-0.7-0.80.7
Time to tail flick, test, after self-admin1.61.73.21.4-1.01.21.51.01.71.3-1.81.21.1-0.5
Delta time to tail flick, vehicle, before/after SA0.30.31.70.40.30.30.0-0.50.10.60.30.9-0.1-1.3
Delta time to tail flick, test, before/after SA1.72.14.01.5-1.41.41.51.21.81.6-2.01.31.0-0.2
Tibia length0.71.94.2-1.31.9-1.4-1.5-2.1-0.9-1.01.4-0.6-1.60.5
Ambulatory time before self-admin0.30.81.6-0.80.4-0.8-0.7-0.1-1.1-1.20.9-1.3-0.61.1
Ambulatory time after self-admin0.30.41.2-0.6-0.1-0.3-0.30.6-1.0-0.90.3-1.1-0.00.8
Bone: tissue strength0.20.20.30.3-0.40.50.40.30.50.4-0.40.40.4-0.5
Total heroin consumption1.51.82.8-1.51.7-1.5-1.4-1.6-0.8-1.30.8-1.2-1.21.3
Bone: trabecular number0.51.01.51.2-1.11.11.21.01.01.1-1.21.00.4-0.5
Bone: trabecular spacing0.30.51.0-0.70.5-0.8-0.6-0.3-0.8-0.80.6-1.0-0.40.8
Bone: trabecular thickness0.40.50.9-0.70.7-0.6-0.8-0.8-0.8-0.61.0-0.4-0.80.1
Bone: trabecular tissue density0.71.21.6-1.21.2-1.1-1.2-1.3-1.0-1.01.1-0.8-1.00.6
Water consumed over 24 hours0.10.10.5-0.60.3-0.2-0.5-0.3-0.7-0.30.3-0.2-0.0-0.2
Number of responses in last shaping day1.01.33.00.5-1.71.50.81.7-0.20.5-0.50.41.5-1.1