Hub : Genes

Dleu7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Dleu7 0.88 0.06 0.0e+00 0.48 0.48 0.52 0.52 2.4e-23 3.6e-23 4.0e-26 1.2e-25
2 NAcc gene expression Dleu7 0.64 0.1 0.0e+00 0.51 0.54 0.54 0.55 3.3e-68 4.4e-75 2.1e-74 2.1e-75
3 LHb gene expression Dleu7 0.47 0.13 2.7e-10 0.23 0.27 0.24 0.26 3.5e-06 4.5e-07 1.8e-06 6.9e-07
4 PL gene expression Dleu7 0.69 0.11 0.0e+00 0.43 0.52 0.52 0.52 7.9e-52 2.7e-67 2.6e-67 3.2e-67
5 Brain gene expression Dleu7 0.62 0 0.0e+00 0.5 0.55 0.55 0.55 3.8e-53 1.7e-60 5.5e-61 7.0e-61
6 IL gene expression Dleu7 0.49 0.17 1.1e-06 0.09 0.16 0.15 0.14 4.5e-03 1.3e-04 1.7e-04 2.7e-04
7 BLA gene expression Dleu7 0.65 0.09 0.0e+00 0.49 0.53 0.53 0.52 1.2e-29 1.0e-32 7.0e-33 8.8e-32
8 RMTg gene expression Dleu7 0.55 0.17 3.1e-13 0.38 0.42 0.39 0.44 3.6e-11 1.7e-12 1.8e-11 3.2e-13
9 OFC gene expression Dleu7 0.63 0.14 6.2e-10 0.23 0.25 0.25 0.25 3.3e-06 1.2e-06 1.3e-06 9.5e-07
10 Eye gene expression Dleu7 0.32 0.19 8.7e-03 0 0.07 0.05 0.06 3.0e-01 2.9e-02 6.4e-02 5.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.30.50.9-0.90.80.5-0.8-0.80.6-0.80.60.50.2
Area under the delay curve2.72.95.91.3-1.7-1.92.01.9-2.41.5-1.8-1.2-0.7
BMI with tail0.30.91.81.3-1.1-0.90.70.8-0.41.3-1.0-0.3-1.2
BMI without tail0.10.10.40.30.10.3-0.4-0.30.50.10.10.6-0.1
Body weight0.62.43.61.4-1.7-1.71.81.5-1.91.5-1.7-0.6-1.2
Weight adjusted by age1.82.03.01.6-1.4-1.41.01.4-0.91.6-1.5-1.6-1.7
Bone surface0.30.50.9-0.80.70.6-0.6-0.70.3-0.90.60.90.8
Bone volume0.30.50.9-0.90.70.5-0.7-0.70.2-0.80.51.00.6
Breakpoint value in progressive ratio session0.00.00.2-0.20.2-0.00.0-0.1-0.3-0.3-0.20.50.2
Number of licking bursts0.10.10.30.5-0.4-0.30.10.4-0.20.4-0.60.1-0.3
Context. condit. distance diff. score0.30.40.9-0.90.70.3-0.3-0.90.5-0.60.8-0.0-0.0
Locomotion velocity, session 12.02.23.11.6-1.5-1.51.41.6-1.01.5-1.4-1.8-1.5
Locomotion distance, session 11.11.41.81.2-1.1-1.21.01.3-1.11.2-1.3-1.1-1.1
Locomotion velocity, session 20.20.20.50.2-0.1-0.60.20.2-0.60.4-0.4-0.4-0.7
Locomotion distance, session 20.00.10.30.10.2-0.2-0.4-0.1-0.10.0-0.20.1-0.5
Locomotion velocity, session 31.01.13.51.0-0.8-1.20.60.5-0.51.1-0.9-1.3-1.9
Locomotion distance, session 31.11.22.61.0-0.9-1.30.80.8-0.91.0-1.1-1.2-1.6
Stereotopy head waving bouts, day 30.91.01.5-1.01.21.1-1.1-1.21.0-0.91.10.70.8
Stereotopy head waving duration, day 30.10.10.30.4-0.3-0.30.30.4-0.30.5-0.3-0.3-0.3
Locomotion velocity, session 70.40.51.1-0.20.70.2-1.0-0.90.9-0.30.4-0.3-1.0
Locomotion distance, session 72.12.63.9-1.81.91.4-1.9-2.01.9-1.81.60.60.5
Stereotopy head waving bouts, day 73.13.44.72.1-1.8-1.91.61.8-1.72.2-1.9-1.6-1.9
Stereotopy head waving duration, day 74.45.36.72.4-2.3-2.52.12.2-2.22.6-2.3-2.1-2.3
Locomotion velocity, session 80.20.21.0-0.3-0.0-0.70.50.2-1.00.1-0.3-0.3-0.3
Locomotion distance, session 80.10.10.5-0.30.2-0.40.1-0.3-0.1-0.10.0-0.7-0.7
Degree of sensitization distance7.27.38.6-2.72.82.9-2.9-2.72.9-2.72.72.12.3
Degree of sensitization stereotypy4.14.45.02.1-2.2-2.22.22.2-2.12.2-2.1-2.0-1.8
Conditioned locomotion1.01.23.8-2.01.30.4-0.3-0.9-0.2-1.51.1-0.51.2
Cocaine response after cond. corrected0.30.30.5-0.60.50.5-0.4-0.50.3-0.60.70.70.7
Cocaine response after cond. not corrected0.30.30.7-0.60.50.5-0.3-0.40.1-0.70.60.70.9
Cocaine response before conditioning0.60.71.10.9-0.9-0.80.81.0-0.70.8-1.0-1.0-0.6
Saline control response0.20.21.4-0.60.20.20.40.1-0.4-0.30.20.21.2
Bone: connectivity density0.61.01.7-1.31.10.9-0.9-1.11.0-1.21.10.30.5
Bone: cortical apparent density1.01.32.21.3-1.2-1.00.91.0-0.41.5-1.1-1.3-1.4
Bone: cortical area0.00.00.10.10.00.0-0.1-0.10.00.00.00.2-0.0
Bone: cortical porosity1.41.54.10.3-0.8-1.51.51.2-2.00.8-1.1-1.4-0.4
Bone: cortical porosity1.41.64.00.4-0.9-1.51.61.3-2.00.8-1.1-1.4-0.5
Bone: cortical thickness0.20.40.60.7-0.6-0.60.50.6-0.50.8-0.6-0.5-0.6
Bone: cortical thickness0.91.11.81.0-1.0-1.20.80.9-0.91.1-1.0-1.1-1.3
Bone: cortical tissue density1.01.32.31.4-1.2-1.00.81.0-0.31.5-1.1-1.3-1.4
Condit. Reinf. active minus inactive responses2.42.73.92.0-1.8-1.51.41.7-0.91.8-1.7-1.6-1.8
Condit. Reinf. active-inactive response ratio0.20.20.70.8-0.4-0.2-0.00.30.40.6-0.4-0.4-0.8
Condit. Reinf. active responses4.15.06.02.3-2.4-2.22.32.4-1.62.2-2.2-2.4-2.3
Condit. Reinf. inactive responses2.12.54.51.0-1.6-1.72.11.8-1.81.1-1.5-1.7-1.0
Incentive salience index mean4.65.56.82.6-2.5-2.32.22.5-1.62.4-2.4-2.4-2.5
Condit. Reinf. lever presses5.47.39.72.8-2.9-2.62.72.9-1.92.6-2.6-3.1-2.6
Condit. Reinf. active minus inactive responses1.01.22.71.2-1.2-0.91.01.2-0.31.1-1.0-1.7-1.1
Condit. Reinf. active-inactive response ratio1.71.83.81.5-1.2-1.10.81.1-0.11.5-1.1-1.9-1.9
Condit. Reinf. active responses1.31.73.51.3-1.4-1.21.31.5-0.71.3-1.2-1.9-1.2
Condit. Reinf. inactive responses0.30.41.6-0.80.50.6-0.0-0.20.1-0.80.60.21.3
Condit. Reinf. lever presses4.66.27.72.8-2.6-2.42.22.6-1.72.6-2.5-2.7-2.6
Condit. Reinf. lever reinforcers received1.82.54.41.6-1.7-1.41.61.8-0.91.6-1.5-2.1-1.4
Conditioned reinforcement - actives5.65.69.0-2.82.52.6-2.0-2.13.0-2.52.70.72.0
Conditioned reinforcement - inactives3.84.35.4-2.02.22.1-2.3-2.12.3-2.12.21.71.4
Conditioned locomotion3.03.65.5-2.32.12.0-1.4-1.71.8-2.12.11.22.0
Patch foraging indifference point 0 sec0.50.93.8-0.60.50.7-0.4-0.5-0.3-0.80.41.91.6
Patch foraging indifference point AUC0.20.20.60.60.10.1-0.8-0.30.60.4-0.10.3-0.7
Delay disc. indifference point, 0s delay0.00.00.2-0.1-0.1-0.20.4-0.0-0.50.1-0.0-0.10.2
Delay disc. indifference point, 16s delay0.70.72.90.1-0.6-0.91.11.0-1.70.3-0.9-0.30.4
Delay disc. indifference point, 2s delay1.71.82.81.1-1.3-1.51.61.4-1.71.4-1.3-1.3-0.8
Delay disc. indifference point, 24s delay0.50.51.20.6-0.6-0.70.71.0-1.10.7-0.8-0.2-0.1
Delay disc. indifference point, 4s delay3.73.95.71.5-2.1-2.22.42.0-2.31.8-1.9-1.9-1.6
Delay disc. indifference point, 8s delay1.81.94.01.1-1.4-1.51.61.5-2.01.3-1.5-0.6-0.5
Indifference point function ln k0.40.51.70.1-0.7-0.71.20.9-1.30.2-0.7-0.30.2
Indifference point function log k0.40.51.70.1-0.7-0.71.20.9-1.30.2-0.7-0.30.2
Patch foraging total patch changes 0 sec0.40.63.1-0.30.10.30.1-0.1-0.8-0.4-0.01.81.3
Patch foraging total patch changes 12 sec0.20.31.10.8-0.4-0.2-0.00.3-0.50.5-0.61.0-0.0
Patch foraging total patch changes 18 sec0.10.10.50.2-0.0-0.10.00.0-0.50.1-0.20.70.3
Patch foraging total patch changes 24 sec0.20.21.20.3-0.3-0.50.40.4-1.10.1-0.60.40.1
Patch foraging total patch changes 6 sec0.20.31.80.30.10.4-0.5-0.30.2-0.00.11.30.4
Patch foraging time to switch 0 sec0.20.30.8-0.90.80.3-0.4-0.50.3-0.50.7-0.60.3
Patch foraging water rate 0 sec0.81.32.41.1-1.4-1.21.41.3-1.50.9-1.30.1-0.5
Patch foraging water rate 12 sec3.24.99.21.8-2.3-2.42.72.6-3.01.8-2.3-1.4-1.0
Patch foraging water rate 18 sec5.97.910.62.9-3.1-3.03.03.0-3.32.5-3.0-1.5-2.2
Patch foraging water rate 24 sec1.11.53.60.8-1.3-1.31.71.4-1.90.7-1.1-0.6-0.3
Patch foraging water rate 6 sec2.33.37.21.3-1.9-2.02.32.1-2.71.4-1.9-0.9-0.6
Seeking ratio, delayed vs. immediate footshock1.01.22.3-1.51.01.0-0.4-0.90.7-1.41.50.21.3
Distance traveled before self-admin0.10.10.4-0.30.0-0.20.50.1-0.30.1-0.1-0.6-0.0
Distance traveled after self-admin0.40.51.2-1.10.90.4-0.2-0.70.4-0.81.0-0.30.5
Extensor digitorum longus weight6.023.530.54.5-5.0-5.35.14.9-5.55.0-5.1-3.8-4.0
Bone: elastic displacement0.50.61.5-1.20.70.4-0.1-0.5-0.3-1.00.70.71.2
Bone: elastic work0.10.20.9-0.1-0.2-0.40.60.3-1.00.1-0.40.30.2
Bone: endosteal estimation0.51.11.5-1.21.11.0-1.1-1.20.9-1.21.01.00.8
Bone: endosteal perimeter0.91.92.6-1.61.51.3-1.3-1.51.1-1.61.51.01.3
Epididymis fat weight0.20.61.8-1.30.90.3-0.0-0.9-0.1-0.80.90.30.8
Delta time in closed arm before/after self-admin0.20.20.4-0.50.40.3-0.2-0.60.0-0.30.40.50.4
Delta time in open arm before/after self-admin3.53.46.3-1.01.62.1-2.3-1.82.5-1.81.81.81.1
Diff in mean of infusions in LGA sessions0.30.31.0-0.80.50.2-0.2-0.6-0.3-0.8-0.01.00.6
Delay discount exponential model param3.73.96.8-1.62.02.2-2.3-2.22.6-1.92.11.51.1
Extinction: sum of active levers before priming0.10.10.2-0.50.50.3-0.3-0.20.4-0.40.20.10.3
Active lever presses in extinction session 60.10.10.5-0.70.6-0.0-0.3-0.3-0.0-0.40.1-0.30.0
Bone: final force0.50.71.10.5-0.6-1.10.80.7-1.00.8-1.0-1.0-0.9
Bone: final moment0.71.21.70.6-0.9-1.31.10.9-1.31.0-1.2-1.2-1.0
Food consumed during 24 hour testing period0.20.30.70.7-0.6-0.50.40.6-0.40.8-0.6-0.1-0.4
Glucose0.40.62.01.1-0.6-0.6-0.00.40.00.9-0.8-0.2-1.4
Heart weight0.20.30.70.7-0.7-0.40.40.8-0.30.5-0.7-0.4-0.4
Delay discount hyperbolic model param4.04.27.2-1.72.12.2-2.4-2.22.7-1.92.11.61.2
Intermittent access intake day 1-15 change1.21.21.6-1.31.21.1-1.0-1.20.8-1.11.00.91.1
Intermittent access intake escalation1.61.62.0-1.41.31.3-1.1-1.31.0-1.31.21.11.4
Intermittent access intake escalation 20.50.50.6-0.60.70.8-0.7-0.80.7-0.80.70.70.7
Intermitt. access day 1 inactive lever presses6.57.011.6-2.12.72.9-3.4-2.52.8-2.52.42.82.0
Intermitt. access day 15 inactive lever presses1.61.82.7-1.31.41.4-1.6-1.31.2-1.51.31.21.1
Intermitt. access escalation Index0.20.20.50.7-0.3-0.1-0.40.30.00.4-0.60.4-0.4
Intermittent access day 1 total infusions0.50.61.5-1.21.00.7-0.6-0.80.7-0.90.70.50.7
Intermittent access day 15 total infusions3.33.74.9-2.22.12.0-2.0-1.91.8-2.11.81.51.7
Intermittent access terminal intake (last 3 days)3.13.34.5-2.12.11.8-2.1-2.01.8-1.91.71.41.2
Intermittent access total infusions4.04.45.7-2.42.32.1-2.1-2.12.0-2.22.11.71.8
Intermittent access day 1 locomotion0.30.30.7-0.90.70.4-0.4-0.40.4-0.60.40.50.4
Intermittent access day 15 total locomotion3.53.85.5-2.32.31.8-1.8-1.81.1-2.11.72.12.1
Intermittent access total locomotion2.02.23.2-1.81.81.4-1.4-1.51.2-1.71.41.41.3
Intermittent access standard deviation1.51.63.2-1.71.31.1-0.8-1.10.3-1.41.21.31.8
Left kidney weight3.08.312.82.7-2.9-3.12.72.7-2.12.8-2.8-3.2-3.6
Right kidney weight4.211.813.13.3-3.6-3.63.63.5-2.93.4-3.3-3.5-3.5
Cocaine induced anxiety0.40.51.00.3-0.7-0.81.00.6-0.90.6-0.5-0.8-0.3
Post-drug Anxiety0.10.10.40.1-0.1-0.30.2-0.2-0.00.2-0.0-0.6-0.5
Baseline Anxiety0.00.00.10.00.10.1-0.1-0.10.3-0.10.2-0.0-0.0
Tail length0.10.20.5-0.5-0.0-0.30.70.2-0.7-0.2-0.0-0.30.4
Length with tail0.10.41.9-0.5-0.3-0.71.00.3-1.4-0.2-0.4-0.20.3
Length without tail0.41.02.30.3-1.0-1.21.30.8-1.50.6-1.0-0.8-0.6
Times rat made contact with spout0.20.20.50.3-0.2-0.40.00.2-0.70.4-0.60.6-0.1
Lifetime Intake3.94.45.6-2.42.22.2-1.9-2.12.0-2.22.11.82.0
Liver weight, left4.06.48.32.6-2.7-2.62.52.7-2.52.6-2.9-1.9-2.1
Liver weight, right0.10.20.30.3-0.4-0.40.50.5-0.50.3-0.4-0.3-0.1
Locomotor activity2.84.48.91.8-2.2-2.32.52.3-3.01.9-2.2-0.9-1.1
Locomotor testing distance0.40.62.50.2-0.6-0.61.00.6-1.60.4-0.60.70.6
Locomotor testing rearing0.20.31.40.5-0.50.00.20.5-0.50.2-0.41.20.6
Locomotion in novel chamber1.11.42.01.1-1.2-1.31.31.1-1.41.2-1.0-1.0-1.0
Locomotion in novel chamber post-restriction0.20.20.4-0.60.6-0.2-0.1-0.6-0.2-0.40.4-0.6-0.2
Fecal boli incidents, locomotor time 12.42.65.42.3-1.9-1.41.21.7-1.41.9-1.8-0.4-1.3
Change in fecal boli incidents, locomotor task2.22.03.0-1.71.71.2-1.5-1.71.1-1.71.60.60.9
Time >=10cm from walls, locomotor time 10.20.21.00.3-0.3-0.50.50.2-0.30.4-0.2-1.0-0.6
Bouts of movement, locomotor time 10.30.40.60.7-0.7-0.60.30.4-0.60.8-0.6-0.0-0.7
Total resting periods, locomotor time 10.20.30.50.7-0.6-0.50.20.3-0.40.7-0.50.2-0.6
Rest time, locomotor task time 12.62.86.62.6-1.9-1.50.81.7-1.01.9-1.9-0.6-2.0
Distance moved, locomotor task time 11.41.54.3-2.11.31.1-0.4-1.10.6-1.41.30.31.5
Vertical activity count, locomotor time 12.02.15.6-2.41.40.9-0.1-1.0-0.3-1.71.40.92.3
Time >=10cm from walls, locomotor time 20.20.20.6-0.80.5-0.1-0.0-0.4-0.1-0.40.3-0.7-0.1
Bouts of movement, locomotor time 20.10.10.10.4-0.2-0.1-0.10.2-0.20.2-0.20.4-0.1
Total resting periods, locomotor time 20.20.20.60.8-0.6-0.40.00.5-0.30.6-0.50.3-0.5
Rest time, locomotor task time 22.12.45.12.3-1.9-1.40.81.7-1.01.6-1.8-0.5-1.8
Distance moved, locomotor task time 20.40.41.8-1.40.60.30.5-0.2-0.3-0.60.5-0.21.1
Vertical activity count, locomotor time 20.90.93.5-1.60.60.40.8-0.2-0.7-0.90.9-0.11.9
Light reinforcement 10.20.31.00.4-0.4-0.80.50.5-1.00.6-0.7-0.3-0.4
Light reinforcement 21.01.32.2-1.51.21.1-0.8-1.30.7-1.11.30.91.3
Bone: marrow area0.61.21.7-1.21.21.0-1.1-1.20.9-1.31.01.00.8
Bone: maximum diameter0.81.52.0-1.31.31.2-1.1-1.30.8-1.41.31.41.3
Bone: maximum force0.30.51.40.1-0.4-0.90.80.6-1.20.5-0.8-0.8-0.4
Bone: maximum moment0.50.92.00.4-0.7-1.21.10.9-1.40.8-1.1-1.0-0.6
Mean time between licks in bursts0.81.22.7-0.50.91.3-1.5-1.11.6-0.70.91.10.6
Mean num. licks in bursts0.00.00.20.0-0.1-0.10.20.1-0.40.0-0.10.30.2
Cd content in liver0.91.02.9-0.50.71.1-1.0-0.90.9-0.80.91.71.1
Co content in liver0.20.20.70.2-0.3-0.50.50.4-0.90.3-0.50.20.0
Cu content in liver1.01.22.81.4-0.9-1.10.40.8-0.51.3-1.3-0.7-1.7
Fe content in liver0.20.31.0-0.20.60.4-0.8-0.61.0-0.10.5-0.1-0.3
K content in liver0.40.30.9-0.90.80.2-0.3-1.00.4-0.40.6-0.4-0.2
Mg content in liver1.41.52.6-1.51.51.1-1.0-1.61.1-1.21.30.50.7
Mn content in liver0.80.92.2-1.51.20.9-0.6-1.20.9-1.01.00.10.8
Na content in liver3.53.78.41.4-1.6-2.11.81.5-1.41.8-1.8-2.9-2.4
Rb content in liver4.35.37.0-2.72.62.3-2.0-2.51.7-2.22.52.02.5
Se content in liver3.03.64.6-2.12.01.9-1.6-1.91.3-2.12.02.02.2
Sr content in liver0.50.41.60.10.30.7-1.0-0.51.3-0.40.40.5-0.3
Zn content in liver0.70.82.40.4-0.8-1.01.01.0-1.50.5-1.1-0.3-0.2
Bone: minimum diameter0.20.51.1-0.60.70.6-0.7-0.70.3-0.70.51.10.7
Time in familiar zone, hab. session 10.50.50.70.6-0.7-0.60.80.8-0.50.9-0.6-0.9-0.5
Time in novel zone, hab. session 10.90.91.7-0.80.90.8-1.1-1.10.5-1.20.71.30.8
Total zone transitions, hab. session 10.50.71.10.9-0.7-0.90.70.7-0.71.0-0.9-0.9-1.0
Total locomotion distance, hab. session 10.00.00.0-0.00.1-0.20.0-0.1-0.20.2-0.20.0-0.1
Locomotion velocity, hab. session 10.10.20.40.1-0.2-0.50.60.3-0.60.5-0.5-0.5-0.3
Time in familiar zone, hab. session 20.40.41.7-1.10.50.40.2-0.3-0.2-0.60.60.31.3
Time in novel zone, hab. session 20.20.21.00.8-0.2-0.2-0.3-0.00.30.3-0.3-0.0-1.0
Total zone transitions, hab. session 21.82.33.51.2-1.3-1.81.51.5-1.91.4-1.6-1.5-1.3
Total locomotion distance, hab. session 20.60.82.70.4-0.5-1.20.90.8-1.70.7-1.0-0.5-0.5
Locomotion velocity, hab. session 20.81.13.10.6-0.7-1.31.01.0-1.80.9-1.2-0.6-0.6
Novel to familiar place preference ratio1.71.82.5-1.31.51.3-1.6-1.51.5-1.41.40.80.7
Novelty place preference1.61.62.4-1.31.41.2-1.5-1.51.4-1.41.40.70.5
Time in novel zone, NPP test1.51.52.2-1.21.31.1-1.4-1.51.4-1.31.30.70.5
Total zone transitions, NPP test1.01.41.91.1-1.1-1.31.11.3-1.31.2-1.4-1.1-1.1
Total locomotion distance, NPP test0.10.20.6-0.10.40.4-0.8-0.30.3-0.30.00.70.2
Locomotion velocity, NPP test0.10.10.50.00.40.3-0.7-0.20.2-0.2-0.10.60.1
Intraocular pressure1.11.52.8-1.51.01.4-0.8-0.91.1-1.41.40.81.7
Delta distance traveled before/after self-admin0.91.01.7-0.80.91.1-1.1-1.11.3-1.01.30.80.6
Delta ambulatory time before/after self-admin0.70.71.0-0.90.90.9-0.8-0.80.9-0.91.00.70.7
Parametrial fat weight3.87.410.0-3.22.92.6-2.2-2.81.7-3.12.72.63.0
Pavlov. Cond. lever latency1.82.33.3-1.81.71.3-1.2-1.80.8-1.51.51.81.5
Pavlov. Cond. magazine entry latency0.30.40.90.6-0.8-0.30.70.7-0.10.4-0.5-1.0-0.4
Pavlov. Cond. change in total contacts1.01.12.11.4-1.3-0.81.11.4-0.81.0-1.1-0.7-0.5
Pavlov. Cond. index score2.73.54.72.2-2.1-1.71.72.2-1.21.8-1.9-2.0-1.7
Pavlov. Cond. latency score2.53.24.52.1-2.0-1.61.62.1-1.01.8-1.8-2.0-1.7
Pavlov. Cond. lever contacts2.63.14.72.0-1.9-1.61.52.0-0.91.7-1.7-2.2-1.8
Pavlov. Cond. magazine entry number1.11.42.2-1.51.41.0-1.1-1.40.7-1.21.21.21.0
Pavlov. Cond. intertrial magazine entries1.82.22.81.3-1.5-1.61.71.5-1.41.5-1.5-1.5-1.3
Pavlov. Cond. lever-magazine prob. diff.3.03.75.12.3-2.2-1.81.72.2-1.21.9-2.0-2.0-1.8
Pavlov. Cond. response bias3.23.95.62.1-2.2-1.92.02.2-1.31.9-1.9-2.4-1.9
Pavlov. Cond. lever latency4.35.87.4-2.72.52.4-2.1-2.41.8-2.72.52.32.5
Pavlov. Cond. magazine entry latency2.62.94.71.4-1.8-1.82.21.8-1.71.6-1.5-2.0-1.2
Pavlov. Cond. change in total contacts4.76.57.42.6-2.6-2.72.62.7-2.52.6-2.7-2.4-2.2
Pavlov. Cond. index score4.76.17.22.5-2.6-2.52.72.7-2.32.5-2.4-2.4-2.0
Pavlov. Cond. latency score4.85.97.02.4-2.6-2.52.62.6-2.22.4-2.4-2.5-2.0
Pavlov. Cond. lever contacts3.85.26.22.5-2.3-2.32.22.4-1.92.4-2.3-2.2-2.2
Pavlov. Cond. magazine entry number2.32.83.7-1.61.71.7-1.9-1.71.6-1.71.61.71.3
Pavlov. Cond. intertrial magazine entries2.73.56.1-1.21.82.1-2.5-1.92.4-1.71.72.01.2
Pavlov. Cond. lever-magazine prob. diff.4.45.66.72.4-2.5-2.42.62.6-2.22.4-2.3-2.4-1.9
Pavlov. Cond. response bias4.66.37.12.5-2.6-2.62.62.7-2.32.6-2.5-2.5-2.2
Time in closed arm before self-admin1.61.82.51.2-1.2-1.61.31.2-1.51.5-1.3-1.4-1.4
Time in closed arm after self-admin2.72.84.21.5-1.7-1.91.91.5-2.01.9-1.6-1.2-1.3
Time in open arm before self-admin0.50.61.5-0.1-0.5-0.91.20.6-1.20.5-0.5-0.9-0.2
Time in open arm after self-admin2.22.44.6-1.11.51.7-2.0-1.62.2-1.51.41.40.7
Bone: periosteal estimation0.51.11.3-1.01.11.0-1.2-1.21.0-1.11.01.10.8
Bone: periosteal perimeter0.40.60.8-0.60.90.8-0.9-0.80.7-0.80.90.80.7
Bone: post-yield work0.10.10.3-0.40.3-0.00.1-0.1-0.5-0.10.00.20.5
Progressive ratio test 1 active lever presses0.90.91.5-1.01.10.9-1.2-1.01.1-0.80.81.00.4
Progressive ratio test 1 breakpoint1.11.11.9-1.11.31.0-1.4-1.11.0-0.90.81.20.6
Progressive ratio test 1 inactive lever presses1.82.03.2-1.21.51.4-1.8-1.31.2-1.41.11.71.2
Progressive ratio test 2 active lever presses3.63.98.5-1.41.92.2-2.6-2.12.9-1.61.71.60.8
Progressive ratio test 2 breakpoint2.73.06.7-1.21.71.9-2.4-1.92.6-1.41.41.50.5
Progressive ratio test 2 inactive lever presses1.41.64.4-0.61.11.5-1.8-1.22.1-0.91.11.10.4
Incentive Sensitization - Responses2.02.06.7-0.51.11.6-2.1-1.52.6-0.91.20.80.0
Incentive Sensitization - Breakpoint1.91.96.1-0.51.11.5-2.0-1.52.5-0.91.10.8-0.0
Sum of active levers in priming session hrs 5-60.10.10.30.20.1-0.1-0.20.10.30.0-0.1-0.4-0.5
Progressive ratio0.10.10.7-0.0-0.2-0.30.50.3-0.8-0.1-0.10.30.4
Food seeking constrained by brief footshock0.40.51.6-0.30.40.8-0.6-0.40.4-0.60.51.31.1
Seeking ratio, punishment vs. effort0.00.00.10.20.10.1-0.20.10.30.1-0.2-0.2-0.1
Retroperitoneal fat weight0.30.92.1-1.40.90.8-0.2-1.10.5-1.01.20.41.0
Reaction time number correct0.10.10.4-0.00.20.4-0.6-0.20.4-0.30.10.60.4
Reaction time mean minus median0.40.52.00.4-0.6-0.60.90.6-0.50.6-0.3-1.4-0.4
Reaction time mean minus median AUC0.20.31.00.7-0.6-0.30.40.40.20.7-0.2-1.0-0.6
Reaction time num false alarms0.10.10.40.2-0.2-0.50.20.1-0.40.4-0.4-0.2-0.6
Reaction time num false alarms AUC0.30.41.00.5-0.4-0.80.30.3-0.60.8-0.7-0.4-1.0
Reaction time trials correct on left0.10.10.4-0.00.20.4-0.6-0.20.4-0.30.10.60.4
Reaction time trials on left0.10.20.5-0.00.30.5-0.7-0.20.5-0.30.20.70.4
Reaction time mean0.20.30.7-0.80.60.3-0.1-0.40.3-0.60.7-0.60.4
Reaction time mean AUC0.30.40.8-0.90.60.5-0.2-0.40.4-0.70.8-0.50.6
Median of all reaction times0.40.51.3-1.10.80.6-0.3-0.60.4-0.90.9-0.30.7
Reaction time omissions1.11.53.7-0.51.01.5-1.5-1.31.9-0.91.41.00.7
Reaction time false alarm rate0.30.41.10.5-0.5-0.90.50.3-0.70.8-0.7-0.4-1.1
Reaction time premature initiation rate0.50.62.00.1-0.5-0.91.00.5-0.70.7-0.7-1.4-0.8
Reaction time premature initiations0.10.20.8-0.0-0.2-0.50.40.2-0.30.4-0.4-0.9-0.4
Std. dev. reaction times0.10.20.6-0.30.30.3-0.1-0.30.5-0.20.5-0.80.1
Reaction time trials completed0.10.20.5-0.00.30.5-0.7-0.20.5-0.30.20.70.4
Reaction time trials AUC0.20.20.6-0.10.40.5-0.7-0.30.4-0.40.30.70.5
Run reversals in cocaine runway, females0.60.51.4-1.00.70.6-0.3-0.80.9-0.41.2-0.50.3
Run reversals in cocaine runway, males1.21.22.11.1-1.4-1.01.41.1-1.11.1-0.9-1.0-0.6
Latency to leave start box in cocaine runway0.60.71.2-0.50.70.9-0.9-0.91.1-0.70.90.90.5
Latency to leave start box in cocaine runway, F1.21.42.3-0.71.01.4-1.4-1.11.5-1.11.01.30.9
Latency to leave start box in cocaine runway, M0.20.20.80.9-0.6-0.20.30.10.10.60.00.2-0.6
Std. dev. time between licks in bursts1.72.02.8-1.61.31.6-1.0-1.31.3-1.51.50.91.7
Total sessions with >9 infusions5.25.87.9-2.42.42.7-2.4-2.32.8-2.42.42.12.0
Short access day 1 total inactive lever presses0.30.30.5-0.60.60.5-0.7-0.50.6-0.60.50.20.2
Short access day 10 total inactive lever presses0.30.31.70.40.20.4-1.0-0.00.2-0.1-0.21.30.4
Short access day 1 total infusions5.65.97.5-2.72.62.6-2.4-2.42.4-2.52.41.92.2
Short access day 10 total infusions0.60.61.6-1.30.80.7-0.1-0.60.2-1.00.70.71.1
Short access total infusions2.52.84.1-2.01.71.8-1.3-1.71.4-1.81.71.51.8
Short access day 1 locomotion2.52.73.9-1.81.61.8-1.4-1.31.3-1.81.52.01.9
Short access day 10 total locomotion0.10.10.30.3-0.3-0.20.50.5-0.10.3-0.3-0.3-0.1
Short access total locomotion0.30.30.5-0.70.50.6-0.3-0.20.5-0.60.40.60.6
One hour access (0.3 mA shock)1.41.62.8-0.91.01.7-1.2-1.01.7-1.11.31.31.4
Compulsive drug intake1.61.62.71.6-1.4-1.11.21.4-0.81.3-1.0-1.4-1.1
One hour access (shock baseline)4.75.56.5-2.52.52.5-2.3-2.32.2-2.52.22.22.4
Social response proportion2.42.63.8-1.71.81.7-1.7-1.72.0-1.71.90.50.9
Social responses0.91.11.8-0.91.01.3-1.1-0.91.3-1.11.20.51.0
Social time0.70.92.31.5-0.7-0.8-0.10.7-0.21.2-0.9-0.7-1.5
Soleus weight0.51.42.11.4-1.5-1.11.21.4-1.11.3-1.4-0.5-0.7
Bone: stiffness0.00.00.10.2-0.0-0.2-0.1-0.1-0.20.2-0.30.2-0.3
Tibialis anterior weight6.321.425.44.8-4.9-5.04.54.6-5.04.8-5.0-3.2-4.1
Time to tail flick, vehicle, before self-admin0.40.42.0-0.1-0.1-0.50.70.2-0.30.6-0.3-1.4-0.5
Time to tail flick, vehicle, after self-admin0.10.10.7-0.2-0.1-0.20.3-0.1-0.80.0-0.00.70.3
Time to tail flick, test, before self-admin1.11.11.41.0-1.1-1.11.10.9-0.91.2-1.0-1.1-1.0
Time to tail flick, test, after self-admin0.90.91.7-0.80.91.1-0.9-0.91.2-0.91.30.30.9
Delta time to tail flick, vehicle, before/after SA0.70.74.0-0.30.40.6-0.9-0.70.1-0.70.52.00.8
Delta time to tail flick, test, before/after SA1.21.12.0-1.01.11.2-1.0-0.91.4-1.11.3-0.00.8
Tibia length0.61.63.71.9-1.5-1.10.71.2-0.71.5-1.5-0.3-1.4
Ambulatory time before self-admin0.80.81.70.4-0.7-1.01.20.9-1.00.8-0.7-1.3-0.6
Ambulatory time after self-admin0.30.31.2-0.50.1-0.60.80.2-0.8-0.00.1-1.1-0.2
Bone: tissue strength0.20.20.3-0.50.60.5-0.5-0.50.5-0.40.40.40.5
Total heroin consumption0.60.71.21.0-1.0-0.60.81.1-0.31.0-0.9-0.8-0.8
Bone: trabecular number0.50.81.7-1.31.00.6-0.8-1.00.9-1.11.00.00.2
Bone: trabecular spacing0.20.20.50.3-0.5-0.50.70.5-0.60.5-0.4-0.4-0.2
Bone: trabecular thickness0.40.50.90.7-0.7-0.80.40.7-0.90.7-0.9-0.2-0.7
Bone: trabecular tissue density0.60.81.61.3-0.9-0.80.60.9-0.71.1-1.0-0.4-0.9
Water consumed over 24 hours0.40.41.00.4-0.7-0.70.70.9-1.00.4-0.9-0.1-0.1
Number of responses in last shaping day2.12.25.1-2.31.61.1-1.0-1.20.2-1.81.21.41.9