Hub : Genes

Dip2b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Dip2b 0.17 0.1 2.4e-11 0.19 0.2 0.22 0.21 1.3e-10 4.9e-11 8.5e-12 1.6e-11
2 RMTg mRNA stability Dip2b 0.13 0.1 2.4e-03 0.11 0.02 0.08 0.06 7.4e-04 1.0e-01 3.0e-03 1.1e-02
3 PL gene expression Dip2b 0.15 0.12 4.3e-15 0.13 0.14 0.15 0.14 5.6e-14 6.3e-15 5.5e-16 1.6e-15
4 pVTA mRNA stability Dip2b 0.15 0.1 1.6e-06 0.11 0.13 0.1 0.1 1.4e-05 3.8e-06 5.7e-05 2.9e-05
5 IL gene expression Dip2b 0.23 0.13 1.1e-05 0.08 0.17 0.09 0.04 5.6e-03 6.9e-05 3.7e-03 3.1e-02
6 Brain mRNA stability Dip2b 0.07 0.05 9.7e-06 0.05 0.06 0.06 0.07 2.5e-05 5.2e-06 2.0e-06 8.4e-07
7 Brain intron excision ratio chr7_131281694_131293033 0.03 0.03 6.1e-03 0.01 0.02 0.01 0.01 6.8e-02 5.7e-03 5.4e-02 4.8e-02
8 PL mRNA stability Dip2b 0.12 0.08 3.7e-15 0.13 0.14 0.13 0.13 2.4e-14 1.2e-14 3.2e-14 2.6e-14
9 LHb mRNA stability Dip2b 0.13 0.1 7.1e-03 0.08 0.06 0.09 0.09 6.6e-03 1.9e-02 4.6e-03 4.1e-03
10 IL mRNA stability Dip2b 0.2 0.13 5.4e-04 0.06 0.13 0.09 0.09 1.3e-02 5.8e-04 3.4e-03 3.5e-03
11 Liver mRNA stability Dip2b 0.04 0.03 5.5e-06 0.05 0.04 0.05 0.05 3.5e-06 1.7e-05 6.3e-06 5.3e-06
12 Adipose gene expression Dip2b 0.12 0.07 1.1e-16 0.13 0.13 0.13 0.13 4.6e-14 6.9e-14 7.9e-14 7.0e-14
13 NAcc mRNA stability Dip2b 0.08 0.05 4.4e-12 0.11 0.1 0.09 0.1 2.5e-12 6.4e-12 8.0e-11 3.2e-11
14 RMTg gene expression Dip2b 0.2 0.15 7.5e-04 0.05 0.03 0.09 0.05 2.2e-02 6.4e-02 2.3e-03 1.5e-02
15 Adipose mRNA stability Dip2b 0.12 0.08 1.1e-12 0.09 0.1 0.09 0.09 2.2e-10 5.1e-11 2.5e-10 1.3e-10
16 BLA mRNA stability Dip2b 0.15 0.1 1.6e-07 0.1 0.13 0.12 0.09 6.2e-06 2.9e-07 4.2e-07 1.2e-05
17 OFC mRNA stability Dip2b 0.53 0.17 1.7e-05 0.27 0.25 0.25 0.26 3.8e-07 1.1e-06 1.2e-06 7.4e-07
18 LHb alternative TSS XM_017595331.2 0.59 0.21 6.4e-03 0.01 0.07 0.02 0.03 2.2e-01 8.3e-03 9.2e-02 6.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density6.911.514.4-3.63.7-3.73.63.53.83.63.63.53.7-3.33.3-3.33.8-2.92.7-3.30.2
Area under the delay curve1.01.11.5-1.11.2-1.11.01.11.01.11.11.21.0-1.21.0-1.10.9-1.11.1-0.60.7
BMI with tail3.712.114.8-3.83.6-3.03.73.83.43.63.63.73.4-3.63.7-3.53.3-3.83.8-2.52.2
BMI without tail0.40.93.6-0.70.70.01.21.01.21.01.00.71.1-0.70.7-0.71.5-0.60.5-1.9-0.6
Body weight4.418.624.5-4.84.9-3.74.64.64.44.54.54.54.4-4.44.4-4.34.3-4.44.3-3.62.1
Weight adjusted by age0.40.52.6-0.71.5-0.40.10.3-0.10.20.20.40.0-0.40.4-0.3-0.3-0.70.90.91.6
Bone surface9.316.420.4-4.24.2-4.44.44.24.54.34.34.24.4-4.04.1-4.14.5-3.63.4-3.90.4
Bone volume8.514.517.7-4.03.9-4.14.14.04.24.04.04.04.1-3.83.8-3.84.2-3.43.2-3.60.5
Breakpoint value in progressive ratio session0.10.10.5-0.30.5-0.00.40.30.20.30.30.30.4-0.00.0-0.10.6-0.00.0-0.7-0.6
Number of licking bursts1.41.73.21.4-1.81.6-1.3-1.2-1.4-1.2-1.3-1.3-1.41.0-1.01.0-1.70.8-0.81.70.7
Context. condit. distance diff. score0.30.41.0-0.50.3-0.60.80.70.70.70.60.40.7-0.60.6-0.60.9-0.40.4-1.0-0.4
Locomotion velocity, session 13.84.15.02.2-1.81.8-2.2-2.2-2.0-2.2-2.2-2.1-2.12.2-2.22.2-2.02.1-2.01.4-1.0
Locomotion distance, session 12.83.64.62.0-1.91.8-2.1-2.1-2.0-2.1-2.1-1.9-2.11.9-1.91.9-2.11.8-1.71.9-0.5
Locomotion velocity, session 20.30.30.60.6-0.50.2-0.6-0.6-0.7-0.6-0.6-0.6-0.50.6-0.60.6-0.50.6-0.70.2-0.4
Locomotion distance, session 23.14.35.82.1-2.01.5-2.3-2.2-2.4-2.2-2.2-2.1-2.22.1-2.12.1-2.42.0-1.92.2-0.4
Locomotion velocity, session 34.24.87.52.4-2.42.7-2.2-2.3-2.0-2.2-2.2-2.3-2.02.3-2.32.3-1.82.4-2.51.1-1.7
Locomotion distance, session 32.52.87.91.8-1.71.8-1.3-1.5-0.9-1.4-1.4-1.8-1.11.7-1.71.7-0.62.2-2.3-0.4-2.8
Stereotopy head waving bouts, day 30.50.64.0-0.10.1-0.0-0.5-0.3-0.7-0.4-0.40.2-0.60.0-0.00.0-1.1-0.40.51.92.0
Stereotopy head waving duration, day 30.20.31.40.2-0.10.3-0.6-0.4-0.5-0.5-0.4-0.1-0.60.3-0.30.3-0.80.1-0.01.20.9
Locomotion velocity, session 72.62.85.01.7-1.51.7-1.6-1.7-1.3-1.6-1.6-1.8-1.41.9-1.91.9-0.92.1-2.20.3-2.2
Locomotion distance, session 73.54.57.02.3-2.02.4-2.0-2.2-1.7-2.0-2.0-2.3-1.82.3-2.32.3-1.42.6-2.70.4-2.4
Stereotopy head waving bouts, day 70.60.73.5-0.80.6-1.10.40.60.20.40.40.90.2-0.70.7-0.7-0.1-1.11.20.81.9
Stereotopy head waving duration, day 71.01.24.7-1.21.0-1.30.70.90.50.80.81.20.5-1.01.0-1.00.2-1.51.60.62.2
Locomotion velocity, session 80.50.60.80.8-0.80.5-0.8-0.8-0.8-0.8-0.8-0.7-0.80.9-0.90.9-0.70.7-0.70.7-0.2
Locomotion distance, session 81.01.42.31.4-1.50.9-1.2-1.2-1.2-1.2-1.2-1.4-1.11.2-1.21.2-1.01.3-1.30.7-0.9
Degree of sensitization distance0.10.11.0-0.00.0-0.0-0.2-0.1-0.4-0.2-0.20.0-0.30.0-0.00.0-0.5-0.20.30.81.0
Degree of sensitization stereotypy0.70.72.8-0.90.7-1.10.60.80.40.60.60.90.4-0.80.8-0.80.2-1.21.30.41.7
Conditioned locomotion0.00.00.20.2-0.50.3-0.1-0.1-0.1-0.0-0.0-0.20.00.1-0.00.00.00.2-0.3-0.2-0.5
Cocaine response after cond. corrected0.10.21.0-0.10.20.3-0.3-0.2-0.4-0.2-0.2-0.0-0.30.0-0.00.0-0.6-0.20.21.00.9
Cocaine response after cond. not corrected0.20.20.80.4-0.30.9-0.5-0.5-0.4-0.5-0.5-0.5-0.50.5-0.50.5-0.60.4-0.40.60.1
Cocaine response before conditioning1.62.04.31.7-1.71.7-1.1-1.3-0.6-1.2-1.2-1.5-1.01.5-1.51.5-0.51.7-1.8-0.4-2.1
Saline control response0.30.32.40.2-0.3-0.10.30.10.60.20.2-0.10.4-0.00.0-0.00.80.3-0.5-1.3-1.5
Bone: connectivity density3.65.77.8-2.52.5-2.62.62.42.72.52.52.52.6-2.32.3-2.32.8-2.01.8-2.5-0.2
Bone: cortical apparent density0.60.83.80.4-0.30.4-1.0-0.9-0.9-0.9-0.9-0.5-1.10.7-0.60.6-1.40.3-0.21.91.0
Bone: cortical area5.68.410.6-3.03.2-2.83.23.13.23.13.12.93.1-2.92.9-2.93.3-2.62.5-3.00.4
Bone: cortical porosity0.40.42.0-0.2-0.1-0.10.60.40.70.60.50.20.7-0.40.4-0.41.00.1-0.2-1.3-1.4
Bone: cortical porosity0.30.32.30.1-0.30.10.30.20.50.30.3-0.10.5-0.10.1-0.10.70.3-0.5-1.1-1.5
Bone: cortical thickness1.52.43.3-1.61.7-1.21.71.71.81.71.61.51.7-1.51.5-1.51.8-1.41.3-1.70.2
Bone: cortical thickness0.30.31.20.6-0.40.9-0.3-0.4-0.0-0.3-0.4-0.7-0.20.5-0.60.60.10.7-0.8-0.7-1.1
Bone: cortical tissue density0.71.04.10.5-0.40.5-1.2-1.0-1.1-1.1-1.0-0.6-1.20.8-0.80.8-1.50.5-0.32.00.9
Condit. Reinf. active minus inactive responses0.10.10.10.3-0.30.3-0.2-0.2-0.2-0.3-0.3-0.4-0.30.2-0.20.2-0.20.2-0.20.1-0.1
Condit. Reinf. active-inactive response ratio0.30.31.0-0.40.4-0.40.60.50.60.50.50.30.6-0.50.5-0.50.8-0.20.2-1.0-0.6
Condit. Reinf. active responses0.70.91.21.0-1.11.0-1.0-0.9-1.0-1.0-1.1-1.0-1.10.9-0.90.9-1.10.7-0.61.10.1
Condit. Reinf. inactive responses3.13.75.91.9-1.91.8-2.1-2.0-2.2-2.1-2.1-1.8-2.21.9-1.91.9-2.41.5-1.32.40.5
Incentive salience index mean0.00.00.1-0.00.0-0.00.10.1-0.10.0-0.0-0.1-0.1-0.10.1-0.1-0.0-0.20.30.10.4
Condit. Reinf. lever presses0.50.62.1-0.80.9-1.00.60.70.30.60.60.70.4-0.80.8-0.80.2-1.11.20.21.4
Condit. Reinf. active minus inactive responses0.81.01.6-0.90.4-0.91.11.11.11.11.01.11.0-1.11.2-1.20.8-1.21.3-0.50.8
Condit. Reinf. active-inactive response ratio0.80.81.1-0.80.3-0.91.01.01.11.00.91.00.9-0.91.0-1.00.8-1.01.0-0.70.5
Condit. Reinf. active responses0.10.10.3-0.3-0.0-0.10.40.40.40.30.30.30.3-0.40.4-0.40.2-0.50.5-0.20.3
Condit. Reinf. inactive responses0.70.91.70.9-0.71.3-0.9-1.0-1.0-1.0-1.0-1.0-1.01.0-1.01.0-0.90.9-0.90.6-0.5
Condit. Reinf. lever presses0.10.10.80.1-0.10.30.20.10.40.20.2-0.00.30.0-0.00.00.50.2-0.3-0.8-0.9
Condit. Reinf. lever reinforcers received0.00.00.30.2-0.50.40.00.00.1-0.0-0.0-0.1-0.00.00.0-0.00.00.00.0-0.1-0.2
Conditioned reinforcement - actives1.11.11.61.0-1.10.8-1.2-1.1-1.1-1.1-1.1-0.9-1.11.0-1.11.0-1.31.0-0.91.1-0.1
Conditioned reinforcement - inactives1.61.82.51.5-1.51.6-1.3-1.4-1.3-1.3-1.4-1.3-1.31.4-1.51.5-1.11.5-1.50.7-1.0
Conditioned locomotion0.10.10.60.3-0.80.4-0.4-0.4-0.3-0.4-0.3-0.3-0.30.3-0.40.3-0.40.4-0.40.0-0.3
Patch foraging indifference point 0 sec5.18.211.03.3-3.03.0-2.7-2.9-2.6-2.8-2.9-3.3-2.73.0-3.03.0-2.13.2-3.20.8-2.7
Patch foraging indifference point AUC0.40.41.30.6-0.80.5-0.7-0.6-0.9-0.6-0.6-0.4-0.70.6-0.50.4-0.90.2-0.11.10.8
Delay disc. indifference point, 0s delay1.71.92.5-1.61.0-1.51.41.51.31.51.51.61.4-1.51.5-1.41.4-1.41.4-0.90.7
Delay disc. indifference point, 16s delay0.90.91.2-1.11.0-0.91.01.01.01.01.01.11.0-1.00.9-1.01.0-0.90.8-0.90.2
Delay disc. indifference point, 2s delay1.82.05.5-1.51.6-1.81.11.30.81.11.11.30.9-1.51.5-1.40.4-1.81.90.32.3
Delay disc. indifference point, 24s delay0.60.51.3-0.81.2-0.50.70.70.80.70.70.70.6-0.80.6-0.80.5-0.80.9-0.50.7
Delay disc. indifference point, 4s delay1.01.11.7-1.10.8-1.21.11.11.21.11.11.31.0-1.11.1-1.01.0-1.11.1-0.70.6
Delay disc. indifference point, 8s delay1.51.52.7-1.21.6-1.11.31.31.51.31.31.31.3-1.31.1-1.21.3-1.11.0-1.30.2
Indifference point function ln k4.86.78.8-2.82.8-2.62.72.73.02.72.72.62.7-2.72.7-2.72.7-2.42.3-2.40.5
Indifference point function log k4.86.78.8-2.82.8-2.62.72.73.02.72.72.62.7-2.72.7-2.72.7-2.42.3-2.40.5
Patch foraging total patch changes 0 sec4.77.510.33.2-2.92.9-2.5-2.8-2.4-2.7-2.7-3.2-2.52.9-2.92.9-1.93.2-3.20.6-2.9
Patch foraging total patch changes 12 sec5.36.98.32.9-2.62.7-2.7-2.7-2.8-2.8-2.8-2.8-2.72.8-2.82.7-2.42.7-2.61.5-1.4
Patch foraging total patch changes 18 sec6.58.310.83.3-3.22.9-2.9-3.0-2.9-2.9-3.0-3.1-2.83.1-3.13.0-2.53.1-3.01.6-1.8
Patch foraging total patch changes 24 sec3.84.76.22.5-2.52.4-2.1-2.2-2.0-2.2-2.2-2.4-2.12.4-2.32.2-1.82.3-2.30.9-1.5
Patch foraging total patch changes 6 sec6.29.211.43.3-3.03.4-3.1-3.1-3.1-3.1-3.2-3.3-3.03.3-3.33.1-2.73.2-3.11.8-1.8
Patch foraging time to switch 0 sec2.23.44.91.9-1.52.2-1.9-1.9-1.9-1.9-1.9-1.7-1.92.0-2.02.0-1.91.8-1.71.5-0.6
Patch foraging water rate 0 sec3.15.06.2-2.32.1-2.22.42.42.52.42.42.22.4-2.32.3-2.32.4-2.22.1-2.20.6
Patch foraging water rate 12 sec2.43.75.1-1.91.8-1.82.12.02.32.12.11.92.2-2.12.0-2.12.1-1.81.6-1.80.2
Patch foraging water rate 18 sec0.40.51.2-0.80.7-1.10.60.70.80.70.70.60.7-1.00.9-0.90.5-0.70.6-0.20.4
Patch foraging water rate 24 sec4.05.67.6-2.52.4-2.82.42.42.42.42.52.62.4-2.62.6-2.52.3-2.42.3-1.61.0
Patch foraging water rate 6 sec5.37.810.5-2.92.7-2.83.03.03.23.03.02.73.0-2.92.9-2.92.9-2.72.5-2.60.8
Seeking ratio, delayed vs. immediate footshock0.60.71.0-0.70.6-0.90.90.90.80.90.90.80.8-1.01.0-1.00.7-0.90.9-0.60.5
Distance traveled before self-admin2.22.33.11.5-1.01.6-1.6-1.7-1.7-1.7-1.7-1.6-1.71.6-1.61.8-1.51.6-1.51.0-0.7
Distance traveled after self-admin0.50.51.00.7-0.60.8-0.7-0.8-0.7-0.7-0.7-0.8-0.60.7-0.70.8-0.40.9-1.00.1-0.8
Extensor digitorum longus weight4.015.825.0-4.54.4-4.23.74.03.33.73.74.43.2-4.14.1-4.12.6-4.85.0-0.84.6
Bone: elastic displacement6.37.18.52.8-2.52.8-2.8-2.8-2.5-2.8-2.7-2.8-2.62.9-2.92.9-2.42.9-2.91.8-1.8
Bone: elastic work0.10.10.5-0.10.60.1-0.1-0.10.2-0.10.0-0.00.10.2-0.20.20.10.4-0.4-0.3-0.7
Bone: endosteal estimation7.215.720.4-4.04.0-4.54.24.14.34.24.23.94.3-4.04.0-4.04.4-3.53.3-4.00.4
Bone: endosteal perimeter6.513.516.2-3.73.6-4.03.93.94.03.93.93.73.9-3.83.7-3.73.9-3.53.3-3.50.9
Epididymis fat weight0.30.84.7-0.10.10.40.70.50.80.60.60.20.9-0.10.00.01.40.3-0.6-2.2-2.0
Delta time in closed arm before/after self-admin0.10.10.2-0.3-0.1-0.30.40.40.30.40.40.20.4-0.40.4-0.40.5-0.20.2-0.4-0.3
Delta time in open arm before/after self-admin3.02.94.62.1-1.82.0-1.5-1.7-1.3-1.6-1.6-1.8-1.41.9-1.91.9-1.02.1-2.20.2-1.9
Diff in mean of infusions in LGA sessions1.31.42.7-1.31.6-1.31.21.30.91.21.11.21.1-1.21.2-1.31.1-1.31.3-0.70.8
Delay discount exponential model param1.01.01.51.1-1.21.1-1.0-1.0-1.0-1.0-1.0-1.1-1.01.1-1.01.0-0.81.1-1.10.5-0.8
Extinction: sum of active levers before priming0.70.71.2-0.90.8-0.50.90.90.60.90.80.90.7-0.90.9-0.90.7-1.01.1-0.60.7
Active lever presses in extinction session 60.10.10.2-0.30.40.10.30.20.20.20.20.40.3-0.10.1-0.10.3-0.20.1-0.40.0
Bone: final force10.416.821.3-4.34.3-3.94.54.34.54.44.44.14.5-4.14.1-4.14.6-3.73.4-4.30.4
Bone: final moment11.919.324.8-4.64.6-4.34.84.64.94.74.74.44.9-4.44.4-4.45.0-3.93.6-4.60.3
Food consumed during 24 hour testing period1.92.33.9-1.41.2-1.41.71.61.81.71.61.21.7-1.61.6-1.61.9-1.21.1-2.0-0.4
Glucose0.30.41.00.8-1.00.9-0.4-0.5-0.4-0.5-0.6-0.7-0.50.6-0.60.6-0.30.6-0.6-0.1-0.6
Heart weight0.20.31.2-0.40.3-0.10.60.40.80.50.50.50.6-0.30.4-0.40.8-0.10.0-1.1-0.8
Delay discount hyperbolic model param1.11.11.61.2-1.31.2-1.0-1.1-1.0-1.0-1.0-1.2-0.91.2-1.11.1-0.71.2-1.20.4-1.0
Intermittent access intake day 1-15 change0.30.32.00.3-1.00.5-0.2-0.3-0.1-0.2-0.1-0.20.00.3-0.40.40.30.7-0.8-0.6-1.4
Intermittent access intake escalation0.30.32.3-0.0-0.70.10.20.10.30.20.20.10.40.0-0.00.00.70.4-0.6-1.0-1.5
Intermittent access intake escalation 20.30.32.10.3-0.90.50.0-0.10.10.00.0-0.30.20.3-0.20.20.50.5-0.7-0.8-1.4
Intermitt. access day 1 inactive lever presses0.30.30.90.5-1.00.5-0.4-0.5-0.4-0.4-0.4-0.6-0.30.5-0.50.5-0.20.7-0.7-0.1-0.9
Intermitt. access day 15 inactive lever presses0.10.10.60.2-0.7-0.1-0.2-0.2-0.0-0.2-0.1-0.3-0.10.1-0.20.2-0.00.4-0.5-0.3-0.8
Intermitt. access escalation Index1.21.12.90.9-0.40.6-1.2-1.0-1.5-1.1-1.1-0.9-1.30.8-0.80.8-1.40.5-0.41.70.9
Intermittent access day 1 total infusions1.01.21.51.2-0.90.9-1.2-1.2-1.1-1.2-1.2-1.1-1.11.1-1.11.2-1.21.2-1.20.9-0.6
Intermittent access day 15 total infusions1.41.62.61.3-1.51.1-1.3-1.3-1.1-1.2-1.2-1.2-1.11.2-1.31.4-0.91.6-1.60.5-1.4
Intermittent access terminal intake (last 3 days)1.41.52.51.3-1.61.1-1.3-1.3-1.3-1.2-1.2-1.2-1.11.2-1.21.3-1.01.5-1.50.6-1.1
Intermittent access total infusions1.31.52.11.3-1.41.1-1.2-1.3-1.2-1.2-1.2-1.1-1.11.2-1.21.3-1.01.4-1.50.7-1.0
Intermittent access day 1 locomotion1.21.22.01.2-0.91.0-1.1-1.2-1.0-1.1-1.1-1.1-1.01.1-1.11.2-0.91.4-1.40.3-1.2
Intermittent access day 15 total locomotion1.01.13.61.1-1.41.2-0.7-0.9-0.5-0.8-0.8-1.0-0.61.0-1.01.1-0.31.4-1.5-0.6-1.9
Intermittent access total locomotion3.23.65.22.1-2.02.0-1.9-2.0-1.7-1.9-1.9-2.0-1.72.0-2.02.1-1.62.2-2.30.6-1.8
Intermittent access standard deviation0.20.21.9-0.1-0.4-0.10.30.20.40.30.30.20.5-0.10.1-0.10.70.3-0.5-0.8-1.4
Left kidney weight1.13.14.7-1.92.1-1.32.01.92.01.91.81.91.9-1.61.7-1.62.1-1.51.4-2.20.0
Right kidney weight2.15.89.6-2.73.1-2.12.62.52.52.52.42.62.4-2.32.4-2.32.4-2.42.3-2.21.0
Cocaine induced anxiety1.21.42.9-1.11.7-1.41.21.11.41.21.21.21.3-0.90.9-0.91.4-0.70.6-1.7-0.5
Post-drug Anxiety5.35.98.5-2.42.9-2.62.62.52.82.52.52.52.6-2.32.3-2.32.6-2.12.0-2.60.3
Baseline Anxiety0.60.71.0-1.00.9-0.50.90.90.80.80.80.60.8-0.90.9-0.90.9-0.91.0-0.40.6
Tail length0.10.42.50.10.30.40.40.20.60.30.2-0.20.50.1-0.10.10.90.5-0.7-1.6-1.5
Length with tail1.65.99.0-2.73.0-2.22.62.62.62.62.62.32.7-2.42.4-2.42.6-2.12.0-2.50.5
Length without tail4.08.711.7-3.43.4-3.03.03.12.83.03.03.22.9-3.13.1-3.12.6-3.13.0-1.81.9
Times rat made contact with spout0.10.10.60.1-0.20.30.20.10.40.10.1-0.10.20.1-0.10.10.50.2-0.2-0.8-0.8
Lifetime Intake1.92.23.31.6-1.51.5-1.5-1.6-1.4-1.5-1.5-1.4-1.31.5-1.61.6-1.21.8-1.80.7-1.4
Liver weight, left1.72.74.4-1.61.5-1.31.91.81.91.81.81.51.9-1.61.6-1.72.0-1.31.2-2.1-0.2
Liver weight, right1.72.95.9-1.61.8-1.21.91.82.01.81.81.42.0-1.61.6-1.62.2-1.21.1-2.4-0.6
Locomotor activity0.81.32.61.1-0.61.6-1.2-1.2-0.9-1.2-1.3-1.4-1.21.3-1.21.2-1.11.3-1.20.4-0.8
Locomotor testing distance2.54.26.92.2-1.92.6-2.0-2.1-1.7-2.1-2.2-2.3-2.02.2-2.22.1-1.72.3-2.20.8-1.6
Locomotor testing rearing1.82.75.41.9-1.62.0-1.3-1.5-0.9-1.5-1.5-1.9-1.31.8-1.81.8-0.82.0-2.0-0.2-2.3
Locomotion in novel chamber2.43.03.8-1.81.2-1.61.81.91.91.81.81.91.7-1.81.8-1.81.7-1.91.9-1.31.0
Locomotion in novel chamber post-restriction0.50.61.2-0.70.6-0.60.90.80.90.90.90.41.0-0.70.8-0.81.1-0.60.5-1.1-0.4
Fecal boli incidents, locomotor time 10.91.02.21.2-1.31.4-0.8-0.9-0.7-0.8-0.9-0.9-0.70.9-1.00.9-0.51.2-1.3-0.1-1.5
Change in fecal boli incidents, locomotor task0.30.31.6-0.61.1-0.40.20.30.20.30.30.50.2-0.40.4-0.3-0.2-0.70.70.41.3
Time >=10cm from walls, locomotor time 10.30.30.50.6-0.10.7-0.5-0.6-0.6-0.5-0.5-0.5-0.50.6-0.70.6-0.40.7-0.70.0-0.5
Bouts of movement, locomotor time 10.10.10.4-0.1-0.20.4-0.1-0.0-0.3-0.1-0.10.0-0.2-0.10.1-0.1-0.4-0.20.20.50.6
Total resting periods, locomotor time 10.50.61.20.7-0.81.0-0.8-0.7-0.9-0.7-0.7-0.7-0.80.6-0.60.5-1.00.5-0.41.10.3
Rest time, locomotor task time 10.70.81.20.9-1.01.1-0.9-0.9-0.9-0.9-0.9-0.8-0.90.8-0.80.8-1.00.8-0.80.8-0.2
Distance moved, locomotor task time 10.00.00.10.0-0.0-0.2-0.2-0.1-0.2-0.1-0.10.1-0.20.1-0.10.2-0.2-0.00.10.40.3
Vertical activity count, locomotor time 10.91.02.0-1.11.4-1.21.01.00.80.90.91.20.9-1.01.0-0.91.0-1.01.0-0.70.5
Time >=10cm from walls, locomotor time 20.30.30.50.6-0.40.2-0.5-0.6-0.6-0.5-0.5-0.2-0.40.6-0.70.6-0.40.7-0.70.2-0.6
Bouts of movement, locomotor time 22.93.13.7-1.91.7-1.61.91.91.81.91.91.71.8-1.91.8-1.91.8-1.81.8-1.40.8
Total resting periods, locomotor time 23.23.44.2-2.11.7-1.71.92.01.91.91.91.81.9-2.02.0-2.01.8-2.02.0-1.31.1
Rest time, locomotor task time 20.20.20.90.4-0.31.0-0.4-0.4-0.3-0.4-0.4-0.6-0.40.4-0.20.4-0.50.2-0.20.50.3
Distance moved, locomotor task time 20.10.10.30.2-0.1-0.5-0.4-0.3-0.5-0.4-0.30.0-0.40.3-0.30.3-0.40.2-0.20.50.1
Vertical activity count, locomotor time 20.10.10.7-0.40.3-0.90.30.30.10.30.30.60.3-0.30.3-0.30.3-0.30.3-0.20.1
Light reinforcement 10.81.42.91.3-1.40.9-1.3-1.2-1.7-1.2-1.2-1.1-1.31.1-1.11.0-1.40.9-0.81.30.2
Light reinforcement 20.10.10.4-0.20.5-0.60.10.1-0.30.10.10.30.0-0.20.2-0.1-0.1-0.30.30.20.6
Bone: marrow area6.814.719.3-3.93.9-4.44.14.04.24.14.13.84.2-3.93.9-3.94.3-3.43.2-3.90.3
Bone: maximum diameter1.62.93.7-1.71.8-1.71.91.81.91.81.81.61.8-1.71.6-1.61.9-1.51.4-1.90.3
Bone: maximum force12.922.327.2-5.15.2-5.05.04.95.05.05.04.95.0-4.94.9-4.94.9-4.54.3-4.11.3
Bone: maximum moment14.725.329.9-5.45.5-5.35.35.35.35.35.35.25.4-5.25.2-5.25.3-4.74.4-4.51.1
Mean time between licks in bursts0.20.21.30.10.3-0.3-0.6-0.4-0.7-0.4-0.3-0.1-0.40.2-0.20.2-0.80.1-0.11.10.7
Mean num. licks in bursts1.11.44.9-0.91.3-1.01.21.01.41.01.00.81.3-0.60.6-0.61.8-0.30.1-2.2-1.7
Cd content in liver0.40.50.80.8-0.90.9-0.7-0.7-0.7-0.7-0.7-0.7-0.60.7-0.70.7-0.60.7-0.70.4-0.4
Co content in liver0.40.52.20.7-0.61.5-0.4-0.5-0.3-0.5-0.6-0.7-0.50.8-0.80.8-0.10.7-0.7-0.3-0.7
Cu content in liver0.40.52.0-0.40.30.20.80.60.80.70.60.20.8-0.50.5-0.51.0-0.20.1-1.4-0.9
Fe content in liver0.91.11.91.0-0.81.4-1.1-1.1-1.1-1.0-1.1-1.1-1.01.2-1.21.2-1.01.1-1.10.7-0.4
K content in liver0.10.10.40.3-0.10.6-0.2-0.2-0.1-0.3-0.3-0.4-0.30.3-0.30.3-0.20.3-0.3-0.0-0.2
Mg content in liver0.20.20.70.5-0.50.8-0.5-0.5-0.5-0.5-0.5-0.6-0.50.4-0.40.4-0.60.4-0.30.40.1
Mn content in liver0.10.10.3-0.40.5-0.30.30.40.20.30.30.20.3-0.40.4-0.40.1-0.50.5-0.20.5
Na content in liver0.30.31.10.5-0.41.0-0.3-0.4-0.1-0.4-0.4-0.5-0.30.6-0.60.6-0.10.6-0.6-0.3-0.8
Rb content in liver1.92.44.41.8-1.72.1-1.4-1.5-1.1-1.5-1.5-1.8-1.41.6-1.61.6-1.11.7-1.70.3-1.5
Se content in liver2.02.54.21.7-1.82.0-1.6-1.6-1.7-1.6-1.6-1.6-1.61.7-1.71.7-1.51.4-1.31.2-0.3
Sr content in liver0.30.21.60.0-0.1-0.00.30.20.40.30.30.20.5-0.10.1-0.10.80.2-0.4-1.1-1.3
Zn content in liver2.42.73.51.8-1.91.9-1.6-1.7-1.7-1.7-1.7-1.8-1.61.6-1.61.6-1.51.7-1.71.0-0.8
Bone: minimum diameter7.614.217.0-4.04.1-4.14.03.93.94.04.03.94.0-3.93.9-3.93.8-3.63.5-3.21.2
Time in familiar zone, hab. session 10.10.10.4-0.1-0.1-0.2-0.00.00.1-0.0-0.00.1-0.1-0.10.1-0.1-0.2-0.30.30.50.6
Time in novel zone, hab. session 10.00.00.1-0.10.2-0.00.00.1-0.20.10.10.10.0-0.20.2-0.2-0.1-0.10.10.10.4
Total zone transitions, hab. session 10.50.73.80.3-0.50.1-0.7-0.5-0.9-0.7-0.6-0.3-0.90.2-0.20.3-1.3-0.20.41.91.7
Total locomotion distance, hab. session 10.50.71.80.6-0.70.9-1.0-0.9-0.9-0.9-0.9-0.7-1.00.6-0.60.6-1.20.5-0.41.40.4
Locomotion velocity, hab. session 10.30.41.20.5-0.60.7-0.7-0.7-0.7-0.7-0.7-0.6-0.80.5-0.50.5-1.00.4-0.31.10.4
Time in familiar zone, hab. session 21.61.62.7-1.31.1-1.61.41.31.51.31.31.31.3-1.31.3-1.31.4-1.31.2-1.10.3
Time in novel zone, hab. session 21.81.82.71.4-1.31.6-1.4-1.4-1.6-1.4-1.4-1.4-1.41.3-1.31.3-1.51.3-1.31.3-0.3
Total zone transitions, hab. session 20.30.40.80.6-0.70.5-0.7-0.6-0.8-0.6-0.6-0.6-0.60.5-0.50.5-0.80.5-0.40.90.2
Total locomotion distance, hab. session 20.50.60.90.8-0.90.8-0.9-0.8-0.9-0.8-0.8-0.9-0.80.7-0.70.7-0.90.7-0.70.9-0.1
Locomotion velocity, hab. session 20.20.30.50.6-0.60.7-0.6-0.6-0.7-0.6-0.5-0.7-0.50.5-0.50.5-0.70.6-0.60.6-0.2
Novel to familiar place preference ratio1.21.22.1-1.21.0-0.81.11.10.61.11.01.10.9-1.21.2-1.20.6-1.41.4-0.21.4
Novelty place preference0.70.71.7-0.90.6-0.50.80.90.30.80.70.80.6-1.01.0-1.00.4-1.11.20.01.3
Time in novel zone, NPP test0.50.51.7-0.70.4-0.30.60.70.20.60.50.70.4-0.80.8-0.80.2-1.01.00.31.3
Total zone transitions, NPP test2.73.95.42.0-1.91.8-2.2-2.1-2.2-2.1-2.1-2.0-2.21.9-1.91.9-2.31.8-1.72.20.0
Total locomotion distance, NPP test3.64.96.22.3-2.32.2-2.5-2.4-2.4-2.4-2.3-2.3-2.32.2-2.22.2-2.52.1-2.02.2-0.4
Locomotion velocity, NPP test2.33.34.11.9-1.81.8-2.0-1.9-2.0-1.9-1.9-1.9-1.91.8-1.81.8-2.01.8-1.71.7-0.4
Intraocular pressure4.15.77.42.7-2.72.3-2.4-2.5-2.2-2.4-2.4-2.6-2.32.6-2.52.6-1.92.6-2.61.2-2.0
Delta distance traveled before/after self-admin0.60.62.5-0.40.1-0.30.80.61.10.80.80.41.0-0.50.5-0.61.2-0.1-0.1-1.6-1.2
Delta ambulatory time before/after self-admin0.50.52.0-0.2-0.1-0.30.60.50.90.60.60.30.8-0.40.4-0.51.10.1-0.3-1.4-1.4
Parametrial fat weight1.02.03.71.6-1.91.9-1.2-1.3-1.0-1.2-1.3-1.5-1.11.5-1.51.5-0.71.6-1.70.1-1.7
Pavlov. Cond. lever latency0.20.21.00.5-0.30.0-0.4-0.5-0.2-0.4-0.3-0.4-0.20.5-0.50.5-0.20.7-0.8-0.1-1.0
Pavlov. Cond. magazine entry latency1.01.22.0-1.21.0-1.31.01.10.61.11.01.10.9-1.31.3-1.30.6-1.41.4-0.11.4
Pavlov. Cond. change in total contacts1.21.32.4-1.31.2-1.01.11.20.81.11.01.20.9-1.21.2-1.20.7-1.51.6-0.21.5
Pavlov. Cond. index score0.70.91.9-1.00.8-0.61.01.00.60.90.80.90.7-1.01.0-1.00.6-1.31.3-0.11.4
Pavlov. Cond. latency score0.60.71.5-0.90.6-0.50.90.90.60.80.70.80.6-0.90.9-0.90.6-1.11.2-0.21.2
Pavlov. Cond. lever contacts0.10.10.3-0.30.20.20.40.40.20.30.30.20.2-0.30.3-0.30.3-0.50.5-0.20.5
Pavlov. Cond. magazine entry number0.40.50.70.7-0.60.8-0.7-0.7-0.4-0.7-0.6-0.6-0.60.8-0.80.8-0.60.8-0.80.4-0.7
Pavlov. Cond. intertrial magazine entries4.75.76.52.5-2.42.6-2.5-2.5-2.3-2.5-2.5-2.5-2.42.5-2.52.5-2.22.5-2.51.8-1.4
Pavlov. Cond. lever-magazine prob. diff.1.01.32.3-1.21.1-0.81.11.20.81.11.01.10.9-1.21.2-1.20.7-1.41.5-0.31.5
Pavlov. Cond. response bias0.30.30.6-0.60.6-0.50.60.60.30.60.50.50.5-0.70.7-0.70.4-0.70.8-0.20.8
Pavlov. Cond. lever latency0.81.11.8-1.31.3-1.31.01.00.81.01.01.10.9-1.21.2-1.20.8-1.21.2-0.40.8
Pavlov. Cond. magazine entry latency0.10.10.20.5-0.30.1-0.4-0.4-0.3-0.3-0.3-0.2-0.20.4-0.40.4-0.30.4-0.50.1-0.2
Pavlov. Cond. change in total contacts0.40.52.1-0.60.3-0.60.60.70.40.60.60.70.4-0.70.8-0.80.2-1.11.10.21.4
Pavlov. Cond. index score0.40.50.91.0-1.00.7-0.7-0.7-0.7-0.7-0.7-0.7-0.70.8-0.80.8-0.70.7-0.80.5-0.3
Pavlov. Cond. latency score0.40.50.90.9-0.90.6-0.7-0.7-0.6-0.6-0.6-0.7-0.60.8-0.70.7-0.60.7-0.70.4-0.3
Pavlov. Cond. lever contacts0.71.01.61.3-1.21.2-0.9-1.0-0.7-0.9-0.9-1.1-0.81.1-1.11.1-0.71.1-1.20.2-0.9
Pavlov. Cond. magazine entry number0.00.00.1-0.20.10.20.10.10.00.00.00.00.0-0.20.1-0.10.1-0.10.10.10.0
Pavlov. Cond. intertrial magazine entries1.72.27.91.5-1.62.1-0.9-1.2-0.6-1.1-1.2-1.7-0.81.5-1.51.5-0.11.9-2.0-0.9-2.8
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.7-0.70.4-0.4-0.4-0.4-0.4-0.4-0.4-0.40.5-0.50.5-0.50.4-0.40.4-0.0
Pavlov. Cond. response bias0.40.51.01.0-1.00.9-0.6-0.7-0.5-0.6-0.6-0.7-0.50.8-0.80.8-0.50.8-0.90.1-0.6
Time in closed arm before self-admin0.80.91.8-1.11.3-1.20.80.90.80.90.91.10.7-0.90.9-0.90.5-1.11.2-0.11.2
Time in closed arm after self-admin0.40.40.9-0.70.3-0.80.50.60.20.50.50.60.4-0.60.6-0.60.2-0.80.90.31.0
Time in open arm before self-admin0.30.42.6-0.50.6-0.4-0.10.0-0.4-0.1-0.10.3-0.3-0.30.3-0.4-0.6-0.60.71.11.6
Time in open arm after self-admin0.30.30.60.5-0.20.5-0.6-0.6-0.7-0.6-0.6-0.5-0.70.5-0.50.5-0.70.4-0.40.70.2
Bone: periosteal estimation9.118.923.2-4.54.6-4.64.74.64.84.64.64.34.7-4.44.4-4.44.8-3.93.6-4.40.6
Bone: periosteal perimeter8.614.316.4-3.93.9-3.94.04.04.04.04.03.94.0-3.93.9-3.93.9-3.73.5-3.41.3
Bone: post-yield work7.810.716.6-3.43.4-4.13.43.43.33.43.43.33.5-3.43.4-3.43.4-3.02.8-2.80.7
Progressive ratio test 1 active lever presses7.27.59.73.0-2.42.8-2.8-2.9-2.8-2.8-2.8-2.8-2.62.9-3.03.0-2.53.1-3.11.6-1.9
Progressive ratio test 1 breakpoint6.16.48.12.8-2.32.5-2.6-2.7-2.6-2.6-2.6-2.6-2.42.6-2.72.7-2.32.8-2.81.5-1.7
Progressive ratio test 1 inactive lever presses1.92.12.61.5-1.51.5-1.5-1.5-1.6-1.5-1.5-1.4-1.41.5-1.51.6-1.31.6-1.60.8-1.0
Progressive ratio test 2 active lever presses1.61.72.71.5-1.31.4-1.2-1.3-1.1-1.3-1.3-1.3-1.11.4-1.41.4-0.91.6-1.60.3-1.4
Progressive ratio test 2 breakpoint1.72.02.91.6-1.51.6-1.3-1.4-1.2-1.3-1.3-1.6-1.21.4-1.51.5-1.01.6-1.70.3-1.4
Progressive ratio test 2 inactive lever presses0.91.12.41.1-1.21.0-0.9-1.0-0.8-0.9-0.9-0.9-0.71.0-1.11.1-0.51.3-1.40.0-1.6
Incentive Sensitization - Responses0.40.40.8-0.50.5-0.40.80.70.80.70.70.50.7-0.70.7-0.50.8-0.50.5-0.9-0.1
Incentive Sensitization - Breakpoint0.30.30.6-0.40.4-0.30.70.60.70.60.60.40.6-0.60.6-0.50.7-0.50.4-0.8-0.0
Sum of active levers in priming session hrs 5-60.50.50.80.7-0.80.7-0.8-0.8-0.9-0.8-0.8-0.6-0.80.7-0.70.7-0.80.6-0.60.80.0
Progressive ratio1.01.11.61.1-0.41.2-1.2-1.2-1.3-1.2-1.1-1.1-1.21.0-1.01.0-1.21.0-1.01.1-0.0
Food seeking constrained by brief footshock1.62.02.61.4-0.91.3-1.6-1.6-1.5-1.6-1.5-1.5-1.51.6-1.61.5-1.41.6-1.51.0-0.6
Seeking ratio, punishment vs. effort0.10.10.3-0.40.1-0.50.40.40.50.40.40.30.4-0.30.2-0.30.5-0.30.3-0.5-0.2
Retroperitoneal fat weight0.93.04.51.9-2.02.1-1.5-1.7-1.6-1.6-1.6-1.9-1.41.9-1.91.9-1.12.0-2.10.3-1.8
Reaction time number correct1.62.46.3-1.31.2-1.41.71.51.91.61.61.21.8-1.31.3-1.32.2-0.80.6-2.5-1.5
Reaction time mean minus median4.86.310.12.9-3.22.8-2.4-2.5-2.1-2.5-2.5-2.8-2.42.6-2.62.6-2.22.6-2.61.3-1.8
Reaction time mean minus median AUC3.64.67.82.4-2.82.4-2.1-2.2-2.0-2.2-2.2-2.3-2.12.3-2.22.2-2.02.1-2.11.4-1.2
Reaction time num false alarms1.41.93.61.4-1.60.9-1.6-1.5-1.5-1.5-1.5-1.3-1.61.2-1.31.3-1.81.1-1.01.90.2
Reaction time num false alarms AUC1.82.45.31.5-1.81.1-1.8-1.6-1.7-1.7-1.7-1.4-1.81.3-1.31.3-2.11.1-0.92.30.5
Reaction time trials correct on left1.62.46.3-1.31.2-1.41.71.51.91.61.61.21.8-1.31.3-1.32.2-0.80.6-2.5-1.5
Reaction time trials on left1.42.05.8-1.11.0-1.31.51.31.81.41.41.01.7-1.11.1-1.12.1-0.60.4-2.4-1.6
Reaction time mean0.50.71.70.9-1.01.3-0.7-0.8-0.5-0.8-0.8-0.9-0.70.9-0.91.0-0.61.0-1.00.0-0.9
Reaction time mean AUC0.30.41.20.7-0.71.1-0.5-0.6-0.3-0.5-0.6-0.6-0.40.7-0.70.7-0.30.8-0.8-0.2-0.9
Median of all reaction times0.00.10.30.0-0.00.50.10.00.30.10.00.00.10.0-0.10.10.20.2-0.2-0.5-0.5
Reaction time omissions6.69.010.93.3-3.23.1-3.0-3.1-2.8-3.1-3.1-3.2-2.93.2-3.23.2-2.53.3-3.31.7-2.2
Reaction time false alarm rate2.53.59.91.6-1.81.4-2.1-1.8-2.2-2.0-2.0-1.5-2.21.5-1.51.5-2.71.0-0.73.11.5
Reaction time premature initiation rate3.74.96.32.4-1.82.3-2.3-2.3-2.2-2.3-2.3-2.4-2.12.4-2.42.4-1.82.5-2.51.2-1.7
Reaction time premature initiations1.52.15.81.5-1.11.4-1.2-1.4-1.0-1.3-1.3-1.6-1.01.6-1.61.6-0.51.9-2.1-0.2-2.4
Std. dev. reaction times4.26.08.62.7-2.92.8-2.5-2.5-2.2-2.5-2.5-2.6-2.42.5-2.52.5-2.32.5-2.41.6-1.3
Reaction time trials completed1.42.05.8-1.11.0-1.31.51.31.81.41.41.01.7-1.11.1-1.12.1-0.60.4-2.4-1.6
Reaction time trials AUC1.92.86.6-1.41.3-1.61.81.62.11.71.81.42.0-1.51.5-1.42.3-1.00.8-2.6-1.4
Run reversals in cocaine runway, females0.60.61.3-0.70.2-0.50.80.71.10.80.90.70.9-0.60.7-0.71.1-0.40.3-1.1-0.6
Run reversals in cocaine runway, males1.01.01.91.0-1.41.2-1.0-0.9-1.2-1.0-1.0-1.2-1.10.8-0.80.8-1.10.6-0.51.20.2
Latency to leave start box in cocaine runway0.30.31.8-0.2-0.2-0.4-0.4-0.2-0.6-0.3-0.3-0.2-0.5-0.20.3-0.2-0.9-0.30.41.31.3
Latency to leave start box in cocaine runway, F2.12.36.21.1-1.40.9-1.8-1.6-1.9-1.7-1.7-1.4-1.91.2-1.11.2-2.20.9-0.72.51.0
Latency to leave start box in cocaine runway, M2.12.12.5-1.51.2-1.51.51.51.51.51.51.41.5-1.61.6-1.61.3-1.61.5-1.00.9
Std. dev. time between licks in bursts1.11.42.01.3-0.91.0-1.3-1.3-1.4-1.2-1.2-1.3-1.21.2-1.21.2-1.21.2-1.20.9-0.3
Total sessions with >9 infusions1.21.31.91.2-1.31.2-1.2-1.2-1.0-1.2-1.2-0.9-1.11.2-1.21.3-1.01.4-1.40.6-1.0
Short access day 1 total inactive lever presses1.11.21.61.2-1.21.1-1.1-1.1-1.3-1.1-1.1-1.1-1.11.1-1.21.2-1.01.2-1.10.7-0.7
Short access day 10 total inactive lever presses0.20.20.9-0.2-0.3-0.20.50.40.50.40.40.20.5-0.20.2-0.20.7-0.0-0.0-0.9-0.9
Short access day 1 total infusions0.50.50.90.8-0.50.7-0.7-0.7-0.7-0.7-0.7-0.6-0.60.7-0.70.9-0.50.9-1.00.2-0.8
Short access day 10 total infusions2.42.73.41.7-1.51.6-1.8-1.8-1.7-1.7-1.7-1.6-1.61.7-1.71.7-1.61.8-1.81.2-1.0
Short access total infusions1.41.62.61.4-1.11.3-1.3-1.3-1.2-1.3-1.3-1.2-1.11.3-1.41.4-1.01.6-1.60.5-1.3
Short access day 1 locomotion0.20.20.50.5-0.40.7-0.5-0.5-0.5-0.5-0.5-0.4-0.50.4-0.40.5-0.60.4-0.40.4-0.1
Short access day 10 total locomotion0.10.10.50.4-0.10.5-0.3-0.4-0.1-0.3-0.3-0.3-0.20.4-0.30.4-0.20.5-0.6-0.2-0.7
Short access total locomotion0.50.50.70.7-0.80.7-0.7-0.7-0.7-0.7-0.7-0.7-0.60.7-0.70.7-0.60.8-0.80.3-0.6
One hour access (0.3 mA shock)0.10.10.2-0.3-0.20.10.30.30.30.30.30.30.3-0.20.1-0.20.3-0.20.2-0.4-0.0
Compulsive drug intake1.61.62.6-1.40.8-1.21.31.41.31.31.21.41.1-1.31.3-1.31.1-1.51.6-0.71.1
One hour access (shock baseline)0.00.00.3-0.1-0.0-0.00.20.10.20.10.10.20.2-0.10.0-0.00.30.1-0.2-0.5-0.5
Social response proportion0.20.21.60.2-0.20.80.1-0.00.20.00.0-0.40.20.2-0.30.30.50.5-0.6-0.9-1.3
Social responses4.55.89.22.7-3.03.0-2.4-2.4-2.4-2.4-2.5-2.8-2.42.4-2.42.4-2.42.3-2.21.8-0.8
Social time0.50.61.7-0.80.7-0.10.80.71.20.80.80.60.9-0.70.7-0.61.0-0.40.2-1.3-0.6
Soleus weight1.02.93.6-1.81.8-1.81.81.81.91.81.81.81.8-1.71.7-1.71.9-1.61.6-1.50.5
Bone: stiffness16.826.632.4-5.65.6-5.75.45.45.35.45.45.35.4-5.45.4-5.45.1-5.14.9-4.12.0
Tibialis anterior weight2.79.424.8-3.33.1-3.02.63.02.02.62.63.42.0-3.13.1-3.11.3-4.04.30.55.0
Time to tail flick, vehicle, before self-admin0.70.71.50.9-0.91.0-0.8-0.8-1.2-0.9-0.9-0.7-0.90.9-0.90.9-0.90.7-0.60.8-0.1
Time to tail flick, vehicle, after self-admin0.50.50.8-0.90.9-0.80.70.80.60.70.70.70.7-0.60.6-0.70.6-0.80.9-0.40.6
Time to tail flick, test, before self-admin0.20.20.70.30.10.2-0.6-0.5-0.6-0.5-0.5-0.3-0.60.4-0.40.4-0.70.2-0.20.90.4
Time to tail flick, test, after self-admin0.80.91.5-1.00.8-0.81.01.00.91.01.01.01.1-0.80.8-0.91.2-0.70.7-1.1-0.3
Delta time to tail flick, vehicle, before/after SA0.90.91.5-0.90.8-0.81.01.01.21.01.00.71.1-0.80.8-0.91.2-0.70.6-1.2-0.2
Delta time to tail flick, test, before/after SA0.90.81.3-0.80.2-0.71.11.01.01.11.00.81.1-0.90.9-0.81.1-0.80.7-1.1-0.2
Tibia length4.512.718.1-3.63.7-3.43.93.74.13.93.83.44.0-3.43.4-3.44.2-3.02.7-4.3-0.1
Ambulatory time before self-admin3.73.94.82.1-1.72.1-2.1-2.1-2.1-2.1-2.1-2.0-2.12.1-2.12.2-1.92.0-1.91.4-1.0
Ambulatory time after self-admin1.51.72.91.5-1.71.5-1.2-1.3-1.0-1.2-1.2-1.3-1.01.3-1.31.3-0.71.6-1.70.1-1.7
Bone: tissue strength1.81.72.9-1.51.5-1.71.21.31.11.21.31.41.2-1.41.4-1.41.0-1.41.4-0.60.9
Total heroin consumption1.41.73.7-1.31.5-1.21.41.31.61.31.31.11.4-1.11.1-1.11.6-0.90.8-1.9-0.4
Bone: trabecular number3.96.29.1-2.52.6-2.72.72.52.92.62.62.52.8-2.32.4-2.43.0-1.91.8-2.8-0.5
Bone: trabecular spacing1.21.63.11.4-1.81.7-1.3-1.2-1.5-1.2-1.3-1.3-1.41.1-1.11.1-1.50.9-0.81.40.3
Bone: trabecular thickness0.50.61.0-0.91.0-0.80.70.70.80.70.70.90.7-0.80.8-0.80.6-0.80.8-0.20.6
Bone: trabecular tissue density1.01.59.1-1.10.8-1.10.40.70.00.60.61.10.3-1.11.1-1.1-0.5-1.51.71.63.0
Water consumed over 24 hours0.40.53.60.3-0.20.60.1-0.00.50.10.0-0.40.30.2-0.20.20.70.7-0.8-1.4-1.9
Number of responses in last shaping day0.30.30.8-0.60.3-0.90.50.50.40.50.60.80.5-0.70.7-0.70.4-0.60.6-0.00.4