Dip2b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Dip2b 0.19 0.13 3.2e-10 0.15 0.19 0.18 0.19 2.2e-08 2.9e-10 9.3e-10 2.2e-10
2 OFC gene expression Dip2b 0.22 0.18 2.8e-03 0.1 0.02 0.08 0.04 2.8e-03 1.1e-01 5.8e-03 4.4e-02
3 PL mRNA stability Dip2b 0.06 0.05 2.3e-07 0.07 0.06 0.06 0.06 9.9e-08 2.2e-07 4.0e-07 5.0e-07
4 Brain mRNA stability Dip2b 0.03 0.03 6.0e-03 0.01 0.02 0.02 0.02 2.0e-02 3.0e-03 3.2e-03 4.3e-03
5 Brain isoform ratio XM_039080375.2 0.03 0.02 4.9e-03 0.02 0.02 0.02 0.02 3.9e-03 2.3e-03 4.7e-03 8.0e-03
6 IL gene expression Dip2b 0.12 0.09 4.6e-03 0.07 0.09 0.04 0.05 9.7e-03 4.2e-03 4.5e-02 2.1e-02
7 Brain intron excision ratio chr7_133160514_133171853 0.04 0.04 5.1e-03 0.02 0.02 0.01 0.02 4.8e-03 3.8e-03 1.7e-02 1.1e-02
8 NAcc mRNA stability Dip2b 0.09 0.06 2.7e-13 0.08 0.09 0.09 0.09 2.6e-12 1.9e-13 8.8e-13 3.2e-13
9 Adipose isoform ratio XR_005487417.2 0.03 0.02 2.2e-04 0.03 0.02 0.02 0.02 6.9e-04 1.2e-03 3.1e-03 2.0e-03
10 pVTA gene expression Dip2b 0.04 0.03 1.7e-04 0.04 0.04 0.04 0.03 3.9e-04 4.9e-04 5.4e-04 1.0e-03
11 IC gene expression Dip2b 0.49 0.21 0.0e+00 0.3 0.3 0.28 0.32 2.8e-13 4.1e-13 3.8e-12 8.9e-14
12 RMTg mRNA stability Dip2b 0.14 0.1 8.8e-04 0.11 0.04 0.11 0.1 9.6e-04 2.7e-02 8.7e-04 1.6e-03
13 LHb mRNA stability Dip2b 0.16 0.13 5.4e-03 0.06 0.01 -0 -0 1.7e-02 1.9e-01 3.4e-01 3.6e-01
14 PL gene expression Dip2b 0.15 0.08 0.0e+00 0.23 0.23 0.23 0.23 1.2e-24 1.2e-24 2.0e-24 2.2e-24
15 Adipose alternative polyA XM_017595330.3 0.02 0.01 8.3e-03 0.01 0.01 0.01 0.01 7.4e-03 1.4e-02 6.0e-02 1.9e-02
16 Adipose alternative polyA XM_063264367.1 0.02 0.02 4.6e-03 0.02 0.01 0.01 0.01 3.8e-03 7.9e-03 1.5e-02 9.1e-03
17 Adipose mRNA stability Dip2b 0.07 0.05 1.0e-08 0.07 0.06 0.06 0.06 4.0e-08 1.1e-07 2.8e-07 1.6e-07
18 Adipose gene expression Dip2b 0.08 0.05 1.3e-11 0.09 0.09 0.09 0.09 3.0e-10 7.5e-10 9.7e-10 1.1e-09
19 pVTA mRNA stability Dip2b 0.07 0.05 7.6e-07 0.09 0.08 0.09 0.09 1.4e-07 6.7e-07 2.2e-07 2.0e-07
20 Liver mRNA stability Dip2b 0.03 0.02 1.5e-03 0.02 0.02 0.01 0.02 2.7e-03 4.4e-03 7.5e-03 3.0e-03
21 IL mRNA stability Dip2b 0.2 0.16 2.4e-03 0.08 0.04 0.05 0.08 6.5e-03 3.7e-02 2.9e-02 5.3e-03
22 BLA mRNA stability Dip2b 0.15 0.11 2.0e-05 0.08 0.09 0.11 0.08 7.5e-05 1.6e-05 2.0e-06 6.3e-05
23 OFC mRNA stability Dip2b 0.3 0.17 6.2e-05 0.2 0.1 0.14 0.14 2.2e-05 1.9e-03 4.2e-04 3.4e-04
24 IC mRNA stability Dip2b 0.09 0.07 7.7e-04 0.11 0.04 0.08 0.09 2.6e-05 1.4e-02 3.8e-04 2.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density6.010.312.83.53.13.03.53.43.33.53.62.9-3.23.3-3.53.13.2-3.13.1-2.6-2.63.33.33.62.13.33.4
Area under the delay curve1.21.32.61.51.31.01.01.01.01.00.91.0-1.21.3-1.51.31.2-1.31.3-1.0-1.01.61.60.81.30.50.0
BMI with tail5.619.427.24.84.64.94.64.64.64.44.44.8-4.64.60.04.94.5-4.94.9-5.2-5.24.14.13.94.73.50.0
BMI without tail1.65.07.32.21.92.62.42.42.42.32.42.5-2.22.10.02.42.2-2.42.4-2.7-2.71.81.82.62.12.40.0
Body weight6.026.133.35.35.25.55.65.65.65.55.55.8-5.35.30.05.45.2-5.45.4-5.6-5.64.74.75.44.54.90.0
Weight adjusted by age0.60.94.11.01.11.10.40.50.60.30.20.6-0.70.8-1.41.60.7-1.61.6-0.9-0.90.60.6-0.22.0-0.80.0
Bone surface8.114.818.14.13.83.84.14.14.04.14.23.7-3.93.8-4.33.83.8-3.83.8-3.4-3.43.83.84.02.93.83.9
Bone volume7.313.116.13.93.43.43.93.93.83.94.03.5-3.73.7-3.93.33.7-3.33.3-3.3-3.33.83.83.82.63.53.8
Breakpoint value in progressive ratio session0.60.71.50.71.21.00.90.90.80.80.90.9-0.80.8-0.71.10.6-1.11.1-1.0-1.00.50.51.00.61.00.0
Number of licking bursts1.22.03.1-1.6-1.6-1.6-1.3-1.3-1.2-1.3-1.4-0.71.4-1.31.7-1.7-1.01.7-1.71.01.0-1.3-1.3-1.8-0.9-1.7-1.3
Context. condit. distance diff. score0.30.41.10.30.10.10.80.70.70.70.80.9-0.40.4-0.30.20.6-0.20.2-1.0-1.00.40.41.00.11.10.3
Locomotion velocity, session 13.84.05.0-2.1-1.9-1.8-2.2-2.2-2.2-2.2-2.2-2.22.1-2.12.1-1.8-2.21.8-1.82.02.1-2.1-2.1-1.8-1.7-1.5-2.2
Locomotion distance, session 13.13.94.6-2.0-1.9-1.8-2.1-2.1-2.1-2.1-2.1-2.11.9-1.92.0-1.8-1.91.8-1.82.12.1-1.9-1.9-2.1-1.5-1.9-2.0
Locomotion velocity, session 20.30.40.8-0.5-0.4-0.4-0.6-0.6-0.7-0.6-0.6-0.80.6-0.60.6-0.5-0.70.5-0.50.90.9-0.6-0.6-0.4-0.7-0.3-0.6
Locomotion distance, session 23.24.46.7-2.0-1.7-1.6-2.3-2.3-2.2-2.2-2.2-2.62.1-2.12.1-1.8-2.11.8-1.82.52.5-2.0-2.0-2.3-1.7-2.2-2.0
Locomotion velocity, session 34.75.47.1-2.5-2.5-2.6-2.2-2.3-2.3-2.2-2.0-2.32.3-2.42.7-2.4-2.32.4-2.42.42.5-2.3-2.3-1.5-2.6-1.2-2.5
Locomotion distance, session 32.62.87.2-1.9-1.9-1.9-1.3-1.4-1.5-1.3-1.0-1.91.7-1.71.9-1.8-1.71.8-1.81.71.7-1.7-1.70.0-2.70.5-1.9
Stereotopy head waving bouts, day 30.30.33.30.20.30.2-0.4-0.3-0.2-0.4-0.7-0.1-0.10.1-0.20.3-0.0-0.30.30.20.20.10.1-1.51.1-1.80.0
Stereotopy head waving duration, day 30.20.21.5-0.00.10.1-0.5-0.4-0.4-0.5-0.6-0.30.2-0.2-0.00.1-0.3-0.10.10.50.5-0.1-0.1-1.10.5-1.2-0.2
Locomotion velocity, session 72.42.64.8-1.8-1.6-1.6-1.5-1.6-1.7-1.5-1.3-2.01.8-1.71.7-1.5-1.91.5-1.51.71.7-1.8-1.8-0.5-2.2-0.1-1.7
Locomotion distance, session 73.34.27.0-2.3-2.1-2.0-1.9-2.0-2.1-1.9-1.7-2.42.2-2.22.3-2.1-2.22.1-2.12.02.0-2.2-2.2-0.9-2.7-0.5-2.1
Stereotopy head waving bouts, day 70.70.82.61.00.80.70.60.70.70.50.31.1-1.00.9-1.00.90.8-0.90.9-0.9-0.91.01.0-0.41.6-0.70.9
Stereotopy head waving duration, day 70.91.12.81.31.00.90.80.90.90.70.51.2-1.21.1-1.21.11.0-1.11.1-0.9-1.01.21.2-0.21.7-0.51.1
Locomotion velocity, session 80.40.50.8-0.8-0.9-0.8-0.7-0.7-0.7-0.8-0.7-0.60.6-0.60.8-0.7-0.90.7-0.70.60.6-0.7-0.7-0.6-0.6-0.6-0.6
Locomotion distance, session 81.11.62.4-1.4-1.4-1.3-1.1-1.2-1.2-1.1-1.0-1.21.3-1.41.5-1.5-1.21.5-1.51.01.1-1.3-1.3-0.8-1.5-0.6-1.3
Degree of sensitization distance0.10.10.90.10.20.3-0.2-0.1-0.1-0.2-0.30.00.00.0-0.10.20.0-0.20.2-0.2-0.2-0.0-0.0-0.80.7-0.90.2
Degree of sensitization stereotypy0.60.61.80.90.60.50.60.70.80.50.41.1-0.90.8-0.90.70.8-0.70.7-1.1-1.11.01.0-0.11.3-0.40.8
Conditioned locomotion0.10.20.5-0.3-0.5-0.5-0.3-0.3-0.3-0.2-0.2-0.50.3-0.40.4-0.5-0.20.5-0.50.70.7-0.2-0.2-0.1-0.6-0.2-0.2
Cocaine response after cond. corrected0.10.10.90.10.00.1-0.3-0.2-0.2-0.3-0.4-0.10.0-0.10.00.0-0.1-0.00.00.40.4-0.0-0.0-0.70.2-1.00.1
Cocaine response after cond. not corrected0.30.30.6-0.5-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.50.5-0.60.6-0.6-0.50.6-0.60.80.8-0.5-0.5-0.6-0.5-0.7-0.5
Cocaine response before conditioning1.92.34.0-1.8-1.8-2.0-1.2-1.3-1.3-1.2-1.0-1.31.6-1.61.8-1.8-1.41.8-1.81.31.3-1.5-1.5-0.3-2.00.2-1.8
Saline control response0.10.21.0-0.4-0.4-0.40.10.0-0.00.10.3-0.10.2-0.20.4-0.5-0.20.5-0.50.10.1-0.3-0.30.9-0.91.0-0.2
Bone: connectivity density3.04.76.52.42.12.12.32.32.22.32.51.9-2.12.1-2.52.22.1-2.22.2-1.5-1.52.22.22.51.42.52.3
Bone: cortical apparent density0.50.74.2-0.3-0.4-0.3-1.0-0.9-0.8-1.0-1.2-1.10.3-0.30.3-0.4-0.50.4-0.40.80.8-0.3-0.3-1.70.4-2.1-0.1
Bone: cortical area6.19.311.23.23.13.23.23.23.23.23.23.1-2.93.0-3.33.02.9-3.03.0-3.0-3.03.03.03.22.32.93.0
Bone: cortical porosity0.20.21.8-0.1-0.1-0.10.60.50.40.60.70.2-0.20.10.0-0.20.40.2-0.2-0.3-0.30.00.01.1-0.71.30.1
Bone: cortical porosity0.20.21.6-0.2-0.2-0.10.30.30.20.40.6-0.10.0-0.10.1-0.30.20.3-0.3-0.0-0.0-0.1-0.11.0-0.91.30.0
Bone: cortical thickness1.83.04.01.71.61.71.91.81.81.81.82.0-1.71.7-1.91.61.6-1.61.6-1.9-1.91.81.81.81.41.61.8
Bone: cortical thickness0.20.20.8-0.5-0.00.2-0.2-0.3-0.3-0.3-0.1-0.40.5-0.50.3-0.1-0.50.1-0.10.40.4-0.6-0.60.5-0.90.8-0.4
Bone: cortical tissue density0.60.84.4-0.4-0.5-0.5-1.1-1.0-0.9-1.1-1.3-1.20.4-0.40.4-0.4-0.60.4-0.40.90.9-0.4-0.4-1.70.3-2.1-0.2
Condit. Reinf. active minus inactive responses0.10.10.3-0.4-0.5-0.5-0.2-0.2-0.2-0.3-0.3-0.30.3-0.30.5-0.6-0.20.6-0.6-0.3-0.3-0.4-0.4-0.2-0.3-0.2-0.2
Condit. Reinf. active-inactive response ratio0.20.20.80.30.20.20.60.50.50.50.60.1-0.30.3-0.30.10.5-0.10.1-0.7-0.60.30.30.8-0.10.90.4
Condit. Reinf. active responses0.70.81.2-1.0-1.0-0.9-1.0-0.9-0.9-1.0-1.0-0.70.9-1.01.1-1.0-0.91.0-1.00.30.4-1.0-1.0-1.0-0.6-1.0-0.9
Condit. Reinf. inactive responses2.73.35.1-1.9-1.7-1.6-2.0-2.0-1.9-2.1-2.2-1.51.8-1.81.9-1.6-1.91.6-1.61.61.6-1.8-1.8-2.2-1.0-2.2-1.9
Incentive salience index mean0.10.10.7-0.1-0.2-0.20.10.10.1-0.0-0.00.2-0.0-0.00.2-0.30.10.3-0.3-0.8-0.8-0.0-0.0-0.00.2-0.10.1
Condit. Reinf. lever presses0.40.51.80.70.50.60.60.60.70.50.40.9-0.70.7-0.60.50.8-0.50.5-1.3-1.20.60.60.11.2-0.20.7
Condit. Reinf. active minus inactive responses0.70.91.80.90.50.41.01.01.11.00.91.3-1.01.0-0.90.61.1-0.60.6-1.2-1.21.21.20.60.90.51.0
Condit. Reinf. active-inactive response ratio0.60.71.20.80.40.30.90.90.90.90.81.0-0.80.8-0.80.30.9-0.30.3-1.1-1.11.11.10.70.60.60.9
Condit. Reinf. active responses0.10.10.40.30.10.00.30.30.30.30.30.6-0.30.3-0.30.20.4-0.20.2-0.5-0.50.40.40.10.30.20.3
Condit. Reinf. inactive responses0.60.71.1-1.0-0.8-0.8-0.9-0.9-0.9-1.0-0.9-0.70.9-0.90.9-0.5-0.90.5-0.50.90.9-1.0-1.0-0.8-0.6-0.6-1.0
Condit. Reinf. lever presses0.00.10.6-0.0-0.0-0.10.20.20.10.30.30.20.00.0-0.10.1-0.1-0.10.10.10.1-0.0-0.00.7-0.30.8-0.1
Condit. Reinf. lever reinforcers received0.00.00.2-0.2-0.4-0.40.00.00.0-0.0-0.00.30.1-0.10.1-0.20.00.2-0.2-0.2-0.2-0.0-0.00.1-0.20.2-0.1
Conditioned reinforcement - actives0.40.61.2-0.7-0.6-0.6-0.8-0.8-0.9-0.8-0.7-1.00.8-0.80.9-0.9-0.70.9-0.91.11.1-0.8-0.8-0.5-1.1-0.40.0
Conditioned reinforcement - inactives3.45.06.9-2.6-2.3-2.3-2.2-2.3-2.3-2.2-2.1-2.22.5-2.52.6-2.5-2.32.5-2.52.22.2-2.3-2.3-1.7-2.6-1.00.0
Conditioned locomotion0.20.20.5-0.2-0.6-0.6-0.4-0.5-0.5-0.4-0.4-0.50.6-0.40.4-0.7-0.50.7-0.70.70.70.00.0-0.2-0.70.00.0
Patch foraging indifference point 0 sec4.88.912.6-3.4-3.5-3.2-2.8-2.9-2.9-2.8-2.6-3.03.2-3.23.5-3.3-3.03.3-3.32.62.6-3.1-3.1-1.7-3.2-0.9-3.0
Patch foraging indifference point AUC0.71.12.1-0.8-1.0-1.1-1.2-1.1-1.1-1.2-1.3-1.10.9-0.90.9-1.0-1.01.0-1.01.11.1-0.7-0.7-1.4-0.3-1.5-0.6
Delay disc. indifference point, 0s delay1.71.83.01.41.31.61.51.51.51.51.51.4-1.71.7-1.21.31.5-1.31.3-1.3-1.31.31.31.31.20.80.0
Delay disc. indifference point, 16s delay0.91.01.71.31.31.00.90.90.90.90.90.9-0.91.0-1.21.10.9-1.11.1-0.8-0.81.31.30.90.90.90.0
Delay disc. indifference point, 2s delay1.82.05.41.81.41.31.01.11.21.00.71.3-1.51.6-1.81.61.5-1.61.6-1.4-1.41.81.80.22.3-0.60.0
Delay disc. indifference point, 24s delay0.50.61.41.00.90.60.60.60.60.60.50.6-0.60.7-1.10.80.7-0.80.8-0.7-0.71.11.10.31.20.20.0
Delay disc. indifference point, 4s delay1.41.52.91.51.41.21.11.21.21.11.11.0-1.31.4-1.31.11.3-1.11.1-1.1-1.11.71.71.11.10.70.0
Delay disc. indifference point, 8s delay1.31.52.31.41.41.01.21.21.11.21.21.0-1.31.3-1.51.51.1-1.51.5-1.0-1.01.31.31.31.01.10.0
Indifference point function ln k3.76.57.52.72.52.62.72.62.62.62.72.4-2.62.6-2.72.42.7-2.42.4-2.6-2.62.52.52.52.02.32.6
Indifference point function log k3.76.57.52.72.52.62.72.62.62.62.72.4-2.62.6-2.72.42.7-2.42.4-2.6-2.62.52.52.52.02.32.6
Patch foraging total patch changes 0 sec4.48.211.6-3.3-3.4-3.2-2.6-2.8-2.8-2.7-2.4-2.93.1-3.13.4-3.2-3.03.2-3.22.52.5-2.9-2.9-1.5-3.3-0.7-2.8
Patch foraging total patch changes 12 sec5.67.29.0-2.9-2.7-2.8-2.8-2.9-2.9-2.9-2.8-2.73.0-3.02.9-2.6-2.92.6-2.62.52.5-2.7-2.7-2.2-2.2-1.7-2.7
Patch foraging total patch changes 18 sec5.58.411.7-3.1-3.4-3.1-2.9-2.9-3.0-2.9-2.8-3.13.0-3.03.1-3.1-3.13.1-3.13.03.0-2.8-2.8-2.1-2.8-1.6-2.2
Patch foraging total patch changes 24 sec3.05.26.9-2.6-2.4-2.6-2.2-2.3-2.3-2.2-2.1-2.22.5-2.52.6-2.5-2.42.5-2.52.12.1-2.3-2.3-1.4-2.3-1.0-1.9
Patch foraging total patch changes 6 sec6.49.812.6-3.5-3.4-3.4-3.1-3.2-3.2-3.2-3.0-3.23.2-3.33.6-3.2-3.33.2-3.22.82.8-3.1-3.1-2.5-2.9-2.0-3.1
Patch foraging time to switch 0 sec1.73.54.3-2.1-2.0-1.6-2.0-2.0-2.0-2.0-2.0-1.72.1-2.02.0-1.6-2.11.6-1.61.91.9-2.1-2.1-1.7-1.4-1.5-2.0
Patch foraging water rate 0 sec2.86.06.92.62.42.32.62.62.62.62.62.6-2.52.4-2.62.32.5-2.32.3-2.6-2.62.52.52.32.02.12.3
Patch foraging water rate 12 sec1.94.05.32.32.22.32.12.12.02.12.21.8-1.92.0-2.32.12.1-2.12.1-1.7-1.71.91.92.01.41.72.2
Patch foraging water rate 18 sec0.30.50.90.90.90.90.70.70.70.70.70.5-0.70.7-0.90.81.0-0.80.8-0.5-0.50.90.90.40.60.10.6
Patch foraging water rate 24 sec4.25.97.82.62.42.72.52.52.52.52.42.2-2.52.5-2.82.62.6-2.62.6-2.3-2.32.42.41.82.31.42.2
Patch foraging water rate 6 sec5.98.610.23.23.22.93.13.13.13.13.12.9-2.92.9-3.22.83.0-2.82.8-2.7-2.73.03.02.82.32.53.1
Seeking ratio, delayed vs. immediate footshock0.30.30.70.40.50.60.70.70.70.70.70.8-0.60.6-0.40.40.8-0.40.4-0.7-0.70.30.30.40.50.50.0
Distance traveled before self-admin1.72.23.9-1.7-2.0-2.0-1.7-1.7-1.7-1.7-1.6-1.61.5-1.51.4-1.3-1.71.3-1.31.51.5-1.3-1.3-1.5-1.1-1.10.0
Distance traveled after self-admin1.01.32.7-1.5-1.5-1.4-1.0-1.1-1.1-0.9-0.7-1.21.1-1.21.2-1.1-1.21.1-1.11.21.2-1.2-1.2-0.2-1.60.20.0
Extensor digitorum longus weight4.617.932.84.64.54.53.83.94.13.63.24.6-4.44.4-4.94.64.1-4.64.6-4.8-4.84.24.21.95.70.94.2
Bone: elastic displacement6.17.110.1-2.8-2.5-2.4-2.7-2.8-2.8-2.7-2.6-3.02.6-2.62.8-2.4-2.82.4-2.43.23.2-2.7-2.7-2.2-2.6-1.8-2.6
Bone: elastic work0.10.10.8-0.2-0.00.1-0.1-0.2-0.2-0.10.0-0.60.1-0.20.1-0.1-0.30.1-0.10.90.9-0.2-0.20.1-0.60.2-0.2
Bone: endosteal estimation6.814.918.04.14.14.14.14.14.04.14.23.6-3.83.7-4.23.83.9-3.83.8-3.6-3.63.73.74.12.73.93.5
Bone: endosteal perimeter6.413.717.34.03.93.83.93.83.83.93.93.7-3.63.6-4.23.73.6-3.73.7-3.4-3.43.63.63.72.93.43.7
Epididymis fat weight0.41.57.50.71.11.21.41.21.11.41.71.1-0.80.80.01.20.7-1.21.2-0.8-0.80.30.32.4-0.32.70.0
Delta time in closed arm before/after self-admin0.10.10.3-0.10.10.10.20.20.20.20.30.1-0.10.10.5-0.50.10.5-0.5-0.3-0.3-0.1-0.10.3-0.50.50.0
Delta time in open arm before/after self-admin0.90.92.4-1.0-1.2-1.2-0.8-0.9-1.0-0.8-0.6-1.21.0-0.80.8-0.8-1.10.8-0.81.21.2-0.8-0.8-0.0-1.60.20.0
Diff in mean of infusions in LGA sessions0.70.91.91.01.21.10.80.80.90.80.71.3-0.60.6-1.11.10.9-1.11.1-1.1-1.11.01.00.41.40.60.0
Delay discount exponential model param1.21.32.8-1.5-1.4-1.0-0.9-1.0-1.0-1.0-0.9-0.91.2-1.31.5-1.3-1.11.3-1.31.01.0-1.7-1.7-0.8-1.4-0.40.0
Extinction: sum of active levers before priming1.92.13.61.31.41.41.51.61.61.51.31.9-1.51.5-1.41.61.6-1.61.6-1.8-1.80.80.81.11.91.00.0
Active lever presses in extinction session 60.20.21.30.20.40.20.40.40.30.40.40.5-0.30.2-0.50.70.2-0.70.7-0.1-0.10.10.11.1-0.11.10.0
Bone: final force10.917.520.64.44.24.34.54.44.44.44.54.1-4.14.2-4.54.04.2-4.04.0-3.9-3.94.24.24.43.14.04.2
Bone: final moment12.319.723.64.74.54.64.84.74.64.84.94.3-4.44.5-4.84.24.4-4.24.2-4.1-4.14.54.54.73.24.44.4
Food consumed during 24 hour testing period1.31.83.21.20.80.71.71.61.61.61.71.4-1.11.2-1.10.71.6-0.70.7-1.8-1.81.41.41.70.61.81.3
Glucose0.20.40.9-0.8-0.6-0.5-0.7-0.7-0.7-0.8-0.7-0.30.9-0.80.0-0.5-0.90.5-0.50.50.5-0.7-0.7-0.4-0.5-0.20.0
Heart weight0.40.63.30.40.60.50.90.80.80.91.10.7-0.40.40.00.60.5-0.60.6-0.5-0.50.30.31.5-0.31.80.0
Delay discount hyperbolic model param1.21.32.7-1.5-1.3-1.0-0.9-1.0-1.0-0.9-0.8-0.91.2-1.31.4-1.3-1.11.3-1.31.01.0-1.6-1.6-0.7-1.4-0.20.0
Intermittent access intake day 1-15 change0.20.31.90.20.60.40.70.60.50.70.80.3-0.40.4-0.10.20.2-0.30.3-0.3-0.30.10.11.2-0.51.40.0
Intermittent access intake escalation0.30.72.30.61.00.81.00.90.91.01.10.8-0.80.7-0.40.50.6-0.60.6-0.7-0.70.40.41.5-0.11.50.0
Intermittent access intake escalation 20.20.21.20.10.40.30.50.50.40.50.70.3-0.40.30.00.10.2-0.10.1-0.3-0.3-0.1-0.10.9-0.41.10.0
Intermitt. access day 1 inactive lever presses0.00.20.6-0.0-0.4-0.3-0.5-0.4-0.4-0.4-0.5-0.40.2-0.20.3-0.7-0.20.7-0.70.30.30.10.1-0.7-0.1-0.80.0
Intermitt. access day 15 inactive lever presses0.10.10.5-0.10.10.10.10.10.10.10.1-0.2-0.20.20.7-0.70.30.7-0.70.20.2-0.1-0.10.5-0.60.10.0
Intermitt. access escalation Index0.20.31.80.20.1-0.0-0.3-0.1-0.1-0.3-0.40.0-0.10.1-0.60.50.2-0.50.5-0.1-0.10.10.1-1.21.3-1.30.0
Intermittent access day 1 total infusions0.91.52.3-1.1-1.5-1.5-1.3-1.3-1.3-1.2-1.1-1.31.4-1.31.1-1.5-1.01.5-1.51.51.5-0.6-0.6-0.8-1.4-0.70.0
Intermittent access day 15 total infusions0.30.51.4-0.7-0.7-0.8-0.6-0.6-0.7-0.5-0.4-0.70.8-0.80.8-1.0-0.61.0-1.00.90.9-0.5-0.5-0.1-1.20.10.0
Intermittent access terminal intake (last 3 days)0.50.71.7-0.8-0.8-0.9-0.7-0.7-0.8-0.7-0.6-0.80.9-0.91.0-1.2-0.71.2-1.21.01.0-0.6-0.6-0.4-1.3-0.00.0
Intermittent access total infusions1.01.22.2-1.1-1.2-1.2-1.0-1.0-1.1-1.0-0.9-1.01.3-1.21.2-1.4-1.01.4-1.41.21.2-0.8-0.8-0.6-1.5-0.30.0
Intermittent access day 1 locomotion0.60.81.9-0.5-1.1-1.1-1.0-1.1-1.1-1.0-0.9-1.31.1-1.00.4-0.8-0.90.9-0.91.41.4-0.1-0.1-0.6-1.0-0.30.0
Intermittent access day 15 total locomotion0.30.52.6-0.4-0.8-0.9-0.3-0.4-0.5-0.20.0-0.50.8-0.70.4-0.8-0.60.8-0.80.70.70.10.10.8-1.61.40.0
Intermittent access total locomotion1.82.14.0-1.3-1.8-1.8-1.4-1.5-1.5-1.4-1.2-1.51.7-1.61.3-1.7-1.51.7-1.71.71.7-0.8-0.8-0.6-2.0-0.10.0
Intermittent access standard deviation0.10.21.4-0.4-0.0-0.00.0-0.1-0.10.10.3-0.50.1-0.20.4-0.2-0.30.2-0.20.50.5-0.4-0.40.6-1.20.90.0
Left kidney weight1.46.610.52.42.82.92.92.92.82.92.93.0-2.52.50.02.82.6-2.82.8-2.7-2.72.02.03.22.02.90.0
Right kidney weight3.917.923.34.44.84.84.64.54.54.54.54.8-4.24.20.04.74.2-4.74.7-4.5-4.53.73.74.53.93.90.0
Cocaine induced anxiety2.12.94.41.61.71.71.81.81.71.81.91.7-1.61.6-2.02.11.6-2.12.1-1.5-1.51.31.32.01.32.10.0
Post-drug Anxiety3.63.86.41.71.92.02.22.12.12.22.31.9-2.01.8-2.02.31.9-2.32.3-1.8-1.81.31.32.31.32.50.0
Baseline Anxiety0.20.20.60.40.40.50.50.60.60.50.50.5-0.60.5-0.20.30.7-0.30.3-0.8-0.80.30.30.20.60.00.0
Tail length0.10.21.9-0.3-0.30.00.40.30.30.50.60.40.0-0.20.0-0.30.00.3-0.30.00.0-0.1-0.11.3-0.81.40.0
Length with tail1.35.79.12.32.42.52.92.82.82.82.92.9-2.42.40.02.32.4-2.32.3-2.3-2.32.22.23.01.52.80.0
Length without tail4.715.119.44.24.23.94.34.34.34.34.24.4-4.14.20.03.94.1-3.93.9-4.1-4.14.04.03.83.33.50.0
Times rat made contact with spout0.10.10.5-0.2-0.5-0.40.20.10.10.20.20.20.2-0.10.3-0.4-0.10.4-0.4-0.5-0.5-0.0-0.00.4-0.40.7-0.1
Lifetime Intake1.62.03.7-1.4-1.6-1.5-1.3-1.4-1.4-1.3-1.2-1.31.7-1.61.5-1.8-1.41.8-1.81.61.6-0.9-0.9-0.8-1.9-0.40.0
Liver weight, left9.014.919.94.14.03.84.44.34.34.44.54.1-4.04.00.03.84.1-3.83.8-3.8-3.83.93.94.42.94.20.0
Liver weight, right2.95.19.42.12.22.52.62.62.52.72.82.2-2.32.20.02.42.5-2.42.4-2.1-2.11.81.83.11.42.90.0
Locomotor activity1.21.93.1-1.8-1.6-1.5-1.3-1.3-1.3-1.3-1.2-1.11.5-1.51.7-1.4-1.41.4-1.41.21.2-1.7-1.7-0.8-1.5-0.5-1.8
Locomotor testing distance2.85.07.2-2.7-2.5-2.4-2.1-2.2-2.2-2.1-2.1-1.92.4-2.32.7-2.4-2.32.4-2.41.91.9-2.6-2.6-1.5-2.3-1.0-2.5
Locomotor testing rearing1.53.15.4-2.2-2.1-1.9-1.5-1.6-1.6-1.5-1.3-1.61.9-1.82.2-1.9-1.81.9-1.91.31.3-2.1-2.1-0.5-2.30.0-2.1
Locomotion in novel chamber4.05.26.22.52.22.32.52.52.52.42.42.5-2.42.5-2.22.02.4-2.02.0-2.4-2.42.42.42.22.02.00.0
Locomotion in novel chamber post-restriction0.10.20.70.40.30.40.60.60.60.60.70.4-0.60.6-0.30.20.6-0.20.2-0.5-0.50.40.40.8-0.10.80.0
Fecal boli incidents, locomotor time 10.60.82.2-1.0-1.0-1.3-0.8-0.8-0.9-0.7-0.6-0.91.0-1.01.1-1.1-1.01.1-1.10.80.8-0.6-0.6-0.2-1.50.00.0
Change in fecal boli incidents, locomotor task0.10.10.50.30.30.4-0.00.00.1-0.0-0.20.0-0.40.4-0.50.50.2-0.50.50.10.10.20.2-0.30.7-0.50.0
Time >=10cm from walls, locomotor time 10.30.40.8-0.6-0.4-0.6-0.7-0.7-0.7-0.6-0.6-0.90.8-0.80.3-0.2-0.80.2-0.20.90.9-0.6-0.6-0.6-0.5-0.20.0
Bouts of movement, locomotor time 10.10.10.8-0.10.20.1-0.2-0.2-0.1-0.2-0.3-0.20.1-0.00.2-0.1-0.00.1-0.10.10.1-0.3-0.3-0.60.2-0.90.0
Total resting periods, locomotor time 10.60.71.9-0.9-0.4-0.6-0.9-0.8-0.8-0.8-0.9-1.00.7-0.71.0-0.7-0.70.7-0.70.90.9-1.0-1.0-1.2-0.6-1.40.0
Rest time, locomotor task time 10.91.11.9-1.2-0.9-0.8-1.0-1.0-1.0-0.9-1.0-1.11.0-0.91.4-1.1-0.91.1-1.11.11.1-1.3-1.3-0.8-1.3-1.00.0
Distance moved, locomotor task time 10.00.00.20.1-0.1-0.1-0.2-0.1-0.1-0.2-0.20.10.0-0.2-0.2-0.1-0.10.1-0.10.00.00.30.3-0.40.4-0.50.0
Vertical activity count, locomotor time 10.51.22.11.21.01.01.01.01.00.90.91.2-1.00.9-1.41.31.0-1.31.3-1.3-1.31.11.10.81.40.90.0
Time >=10cm from walls, locomotor time 20.30.40.9-0.7-0.5-0.5-0.7-0.7-0.7-0.6-0.6-1.00.9-0.80.7-0.5-0.70.5-0.50.80.8-0.7-0.7-0.5-0.8-0.40.0
Bouts of movement, locomotor time 22.13.44.42.11.71.92.02.02.02.01.91.9-2.12.0-1.91.72.0-1.71.7-1.9-1.92.02.01.41.81.30.0
Total resting periods, locomotor time 22.13.75.12.11.72.02.02.12.12.01.92.1-2.22.2-2.01.72.2-1.71.7-2.1-2.12.02.01.41.91.30.0
Rest time, locomotor task time 20.30.40.9-0.9-0.8-0.5-0.6-0.5-0.5-0.5-0.6-0.30.4-0.40.8-0.6-0.40.6-0.60.50.5-0.9-0.9-0.7-0.6-0.80.0
Distance moved, locomotor task time 20.10.10.40.10.2-0.0-0.3-0.3-0.3-0.4-0.4-0.20.4-0.4-0.10.0-0.3-0.00.00.20.20.10.1-0.40.3-0.60.0
Vertical activity count, locomotor time 20.20.20.50.70.50.50.40.40.40.30.30.3-0.30.3-0.60.50.4-0.50.5-0.6-0.60.60.60.40.70.30.0
Light reinforcement 10.71.83.4-1.4-1.8-1.3-1.4-1.3-1.3-1.3-1.4-1.21.3-1.31.4-1.4-1.21.4-1.41.31.3-1.3-1.3-1.5-0.8-1.4-1.0
Light reinforcement 20.00.10.40.2-0.3-0.30.00.10.10.1-0.00.4-0.00.1-0.2-0.10.20.1-0.1-0.2-0.20.40.4-0.10.3-0.20.6
Bone: marrow area6.413.917.04.03.94.04.03.93.94.04.13.5-3.63.6-4.03.73.7-3.73.7-3.5-3.53.63.64.02.63.83.4
Bone: maximum diameter1.83.35.01.92.12.21.91.81.81.81.91.8-1.61.6-2.12.01.5-2.02.0-1.7-1.71.61.61.91.41.81.7
Bone: maximum force13.323.629.45.35.15.35.05.05.05.05.04.7-4.94.9-5.44.85.0-4.84.8-4.5-4.55.05.04.54.13.94.8
Bone: maximum moment14.926.232.65.65.35.55.35.35.35.35.34.9-5.25.2-5.75.15.2-5.15.1-4.7-4.75.25.24.84.14.25.1
Mean time between licks in bursts0.10.31.5-0.3-0.2-0.3-0.6-0.5-0.6-0.5-0.6-0.80.2-0.30.3-0.3-0.40.3-0.31.01.0-0.4-0.4-0.9-0.2-1.2-0.3
Mean num. licks in bursts0.81.24.61.00.91.01.11.00.91.01.30.4-0.90.9-1.11.00.6-1.01.0-1.0-1.01.01.01.90.12.10.9
Cd content in liver0.30.30.6-0.7-0.7-0.8-0.4-0.4-0.4-0.4-0.4-0.50.5-0.50.7-0.7-0.40.7-0.70.30.3-0.6-0.6-0.4-0.5-0.3-0.7
Co content in liver0.20.20.4-0.5-0.6-0.2-0.4-0.5-0.5-0.6-0.50.10.7-0.60.4-0.3-0.60.3-0.3-0.2-0.2-0.4-0.4-0.1-0.10.0-0.6
Cu content in liver0.20.32.1-0.0-0.00.30.60.50.50.60.70.5-0.20.2-0.10.20.4-0.20.2-0.5-0.50.10.11.2-0.31.4-0.2
Fe content in liver1.41.72.8-1.4-1.4-1.3-1.3-1.4-1.4-1.3-1.3-1.31.4-1.31.3-1.1-1.51.1-1.11.71.7-1.3-1.3-1.0-1.3-0.8-1.4
K content in liver0.10.10.4-0.4-0.1-0.0-0.4-0.4-0.4-0.4-0.3-0.30.5-0.50.4-0.2-0.40.2-0.20.20.2-0.6-0.6-0.1-0.50.1-0.3
Mg content in liver0.20.20.7-0.5-0.8-0.4-0.4-0.4-0.4-0.4-0.3-0.40.5-0.50.5-0.6-0.30.6-0.60.40.4-0.5-0.5-0.1-0.7-0.0-0.2
Mn content in liver0.10.10.4-0.2-0.1-0.1-0.3-0.3-0.2-0.3-0.4-0.20.3-0.20.2-0.2-0.10.2-0.20.00.0-0.3-0.3-0.50.1-0.6-0.1
Na content in liver0.10.10.80.10.00.20.30.20.20.20.30.40.00.1-0.10.10.0-0.10.1-0.4-0.4-0.0-0.00.7-0.20.90.4
Rb content in liver1.41.62.8-1.6-1.7-1.4-1.1-1.2-1.2-1.1-1.0-0.91.4-1.51.6-1.5-1.31.5-1.50.80.8-1.4-1.4-0.4-1.6-0.0-1.5
Se content in liver3.44.05.0-2.2-2.1-2.0-2.0-2.1-2.1-2.0-1.9-1.92.2-2.12.2-1.9-2.21.9-1.92.12.1-2.2-2.2-1.5-2.0-1.2-2.0
Sr content in liver0.50.51.30.60.00.40.80.80.80.90.90.6-0.60.7-0.50.30.7-0.30.3-0.6-0.60.70.71.10.01.10.7
Zn content in liver0.91.02.0-1.2-1.4-1.0-0.8-0.9-0.9-0.8-0.7-0.91.0-1.11.2-1.1-0.91.1-1.11.11.1-1.1-1.1-0.4-1.3-0.2-0.9
Bone: minimum diameter7.413.516.84.03.83.73.93.93.83.93.93.6-3.73.7-4.13.63.8-3.63.6-3.4-3.43.73.73.43.03.03.8
Time in familiar zone, hab. session 10.00.00.2-0.0-0.2-0.2-0.00.00.1-0.1-0.10.2-0.20.10.0-0.20.10.2-0.2-0.3-0.30.20.2-0.30.2-0.40.3
Time in novel zone, hab. session 10.00.00.10.10.10.10.00.00.10.10.00.1-0.00.1-0.00.00.2-0.00.00.30.20.00.0-0.20.1-0.3-0.1
Total zone transitions, hab. session 10.30.43.9-0.2-0.2-0.2-0.7-0.6-0.5-0.7-0.9-0.40.2-0.20.3-0.3-0.20.3-0.30.10.1-0.2-0.2-1.50.6-2.0-0.1
Total locomotion distance, hab. session 10.50.61.9-0.6-0.5-0.6-0.9-0.9-0.8-0.9-1.0-1.00.7-0.70.7-0.6-0.60.6-0.60.80.8-0.7-0.7-1.2-0.3-1.4-0.6
Locomotion velocity, hab. session 10.30.41.3-0.4-0.4-0.4-0.7-0.7-0.6-0.7-0.8-0.80.5-0.50.6-0.5-0.50.5-0.50.60.6-0.5-0.5-1.0-0.2-1.2-0.4
Time in familiar zone, hab. session 21.71.72.51.31.11.21.41.41.31.31.31.4-1.31.4-1.41.21.3-1.21.2-1.6-1.61.31.31.31.21.21.4
Time in novel zone, hab. session 22.02.02.4-1.4-1.3-1.4-1.5-1.4-1.4-1.4-1.4-1.41.4-1.51.5-1.3-1.31.3-1.31.61.6-1.4-1.4-1.5-1.2-1.5-1.5
Total zone transitions, hab. session 20.30.41.0-0.6-0.5-0.5-0.6-0.6-0.6-0.6-0.7-0.70.5-0.50.6-0.6-0.50.6-0.60.70.6-0.5-0.5-0.9-0.5-1.0-0.4
Total locomotion distance, hab. session 20.60.71.4-0.7-0.7-0.8-0.9-0.8-0.8-0.8-0.8-1.00.8-0.70.9-0.9-0.70.9-0.91.21.1-0.7-0.7-1.0-0.9-1.1-0.6
Locomotion velocity, hab. session 20.30.51.0-0.6-0.6-0.7-0.6-0.6-0.6-0.5-0.6-0.80.6-0.50.7-0.8-0.50.8-0.81.00.9-0.5-0.5-0.7-0.8-0.8-0.4
Novel to familiar place preference ratio1.01.11.91.10.70.61.01.11.21.00.91.4-1.11.2-0.90.71.2-0.70.7-1.3-1.31.21.20.31.30.01.2
Novelty place preference0.50.61.30.80.40.30.70.80.90.70.61.1-0.80.9-0.60.41.0-0.40.4-1.0-1.00.90.90.11.0-0.20.9
Time in novel zone, NPP test0.30.40.90.60.30.10.50.60.70.50.41.0-0.70.7-0.40.20.8-0.20.2-0.9-0.90.70.7-0.11.0-0.40.8
Total zone transitions, NPP test3.04.45.6-2.1-2.0-1.9-2.2-2.2-2.1-2.2-2.2-2.12.0-2.02.2-2.0-2.02.0-2.02.42.3-2.0-2.0-2.3-1.7-2.3-1.9
Total locomotion distance, NPP test4.15.68.5-2.4-2.3-2.3-2.4-2.4-2.4-2.3-2.4-2.52.3-2.32.5-2.3-2.22.3-2.32.92.8-2.2-2.2-2.4-2.1-2.3-2.2
Locomotion velocity, NPP test2.73.96.3-2.0-1.9-2.0-2.0-2.0-1.9-1.9-1.9-2.01.9-1.92.1-2.0-1.82.0-2.02.52.4-1.8-1.8-2.0-1.8-1.9-1.8
Intraocular pressure5.17.410.9-3.0-3.3-2.8-2.6-2.7-2.7-2.6-2.5-2.82.7-2.73.2-3.0-2.73.0-3.02.52.5-2.8-2.8-1.9-2.8-1.4-2.5
Delta distance traveled before/after self-admin0.40.43.5-0.10.10.20.60.50.40.60.90.2-0.10.00.2-0.10.20.1-0.1-0.0-0.0-0.1-0.11.6-1.21.90.0
Delta ambulatory time before/after self-admin0.30.42.5-0.4-0.00.10.40.30.20.50.7-0.10.1-0.20.5-0.30.00.3-0.30.20.2-0.5-0.51.3-1.51.60.0
Parametrial fat weight0.30.71.4-0.9-1.2-0.8-0.9-0.9-1.0-0.9-0.8-0.71.1-1.10.0-1.0-1.11.0-1.00.80.8-0.8-0.8-0.5-1.0-0.40.0
Pavlov. Cond. lever latency0.30.31.3-0.4-0.5-0.5-0.5-0.5-0.5-0.4-0.3-0.90.4-0.40.5-0.6-0.40.6-0.61.11.0-0.3-0.3-0.2-1.0-0.2-0.4
Pavlov. Cond. magazine entry latency1.21.52.61.21.31.41.21.21.21.11.01.4-1.11.1-1.31.41.3-1.41.4-1.5-1.51.01.00.71.60.51.0
Pavlov. Cond. change in total contacts1.61.73.71.31.41.41.21.21.31.11.01.5-1.21.2-1.41.51.2-1.51.5-1.7-1.71.21.20.61.90.31.1
Pavlov. Cond. index score1.11.43.31.11.21.31.11.11.20.90.81.5-1.01.0-1.21.31.1-1.31.3-1.8-1.70.90.90.61.70.40.9
Pavlov. Cond. latency score0.91.12.90.91.01.11.01.01.10.80.81.4-0.90.9-1.01.11.0-1.11.1-1.7-1.60.80.80.61.60.40.9
Pavlov. Cond. lever contacts0.20.31.10.40.40.50.50.50.50.40.30.8-0.40.4-0.40.50.4-0.50.5-1.1-1.00.30.30.30.90.30.3
Pavlov. Cond. magazine entry number0.70.81.6-0.8-1.0-1.1-0.9-0.9-0.9-0.8-0.7-1.20.7-0.70.9-1.1-0.91.1-1.11.31.2-0.7-0.7-0.6-1.2-0.5-0.5
Pavlov. Cond. intertrial magazine entries4.65.56.4-2.4-2.2-2.3-2.5-2.5-2.5-2.5-2.4-2.52.5-2.42.5-2.1-2.52.1-2.12.42.4-2.4-2.4-2.1-2.1-1.7-2.4
Pavlov. Cond. lever-magazine prob. diff.1.41.83.71.31.41.51.21.21.31.11.01.6-1.21.2-1.41.51.3-1.51.5-1.9-1.81.11.10.71.90.41.1
Pavlov. Cond. response bias0.40.51.10.60.70.80.60.70.70.60.50.9-0.60.5-0.70.80.7-0.80.8-1.0-1.00.50.50.41.00.30.4
Pavlov. Cond. lever latency0.91.21.71.21.21.31.01.01.11.00.90.8-1.21.2-1.11.01.3-1.01.0-1.3-1.31.11.10.51.20.31.2
Pavlov. Cond. magazine entry latency0.20.20.7-0.3-0.1-0.2-0.5-0.5-0.5-0.4-0.4-0.40.6-0.50.2-0.1-0.60.1-0.10.80.8-0.4-0.4-0.4-0.3-0.2-0.5
Pavlov. Cond. change in total contacts0.30.52.00.70.50.40.70.70.80.60.51.4-0.70.7-0.70.60.8-0.60.6-1.0-1.00.80.80.21.1-0.00.7
Pavlov. Cond. index score0.30.30.7-0.6-0.5-0.6-0.6-0.6-0.6-0.5-0.6-0.20.7-0.70.5-0.4-0.80.4-0.40.80.8-0.6-0.6-0.4-0.6-0.3-0.7
Pavlov. Cond. latency score0.30.40.8-0.7-0.6-0.7-0.7-0.7-0.7-0.6-0.6-0.30.8-0.80.6-0.4-0.80.4-0.40.90.9-0.7-0.7-0.5-0.6-0.4-0.8
Pavlov. Cond. lever contacts0.60.91.4-1.1-1.0-1.1-0.8-0.9-0.9-0.8-0.8-0.71.1-1.01.0-0.8-1.20.8-0.81.21.2-1.0-1.0-0.3-1.2-0.2-1.0
Pavlov. Cond. magazine entry number0.00.00.1-0.1-0.2-0.00.10.10.10.00.0-0.1-0.10.10.2-0.30.30.3-0.3-0.3-0.30.00.00.0-0.1-0.10.1
Pavlov. Cond. intertrial magazine entries1.62.55.6-2.0-1.9-1.8-1.1-1.2-1.3-1.2-0.8-1.31.7-1.72.0-1.8-1.61.8-1.81.01.0-1.8-1.80.1-2.40.8-1.7
Pavlov. Cond. lever-magazine prob. diff.0.20.20.4-0.5-0.4-0.5-0.5-0.5-0.5-0.4-0.5-0.10.6-0.60.4-0.3-0.70.3-0.30.60.6-0.5-0.5-0.4-0.4-0.3-0.6
Pavlov. Cond. response bias0.30.40.7-0.7-0.6-0.7-0.5-0.6-0.6-0.5-0.5-0.30.7-0.70.6-0.5-0.80.5-0.50.80.8-0.6-0.6-0.2-0.8-0.0-0.7
Time in closed arm before self-admin1.31.64.31.51.41.31.01.01.10.90.81.1-1.21.0-1.71.81.1-1.81.8-1.1-1.11.41.40.12.1-0.20.0
Time in closed arm after self-admin0.20.20.80.50.70.70.30.40.40.30.10.6-0.40.3-0.10.20.4-0.20.2-0.6-0.60.40.4-0.50.9-0.70.0
Time in open arm before self-admin0.50.51.8-0.6-0.7-0.7-0.9-0.8-0.7-0.9-1.0-0.50.6-0.60.5-0.6-0.50.6-0.60.50.5-0.6-0.6-1.20.3-1.40.0
Time in open arm after self-admin0.20.20.5-0.5-0.7-0.7-0.6-0.6-0.6-0.6-0.5-0.60.4-0.30.1-0.1-0.50.1-0.10.60.6-0.6-0.6-0.3-0.3-0.30.0
Bone: periosteal estimation9.319.623.04.74.54.64.74.74.64.74.84.4-4.34.3-4.84.34.4-4.34.3-4.2-4.24.34.34.73.24.34.2
Bone: periosteal perimeter8.614.818.44.14.04.14.04.04.04.04.03.9-3.83.7-4.33.83.8-3.83.8-3.7-3.73.83.83.83.23.53.8
Bone: post-yield work6.89.913.83.53.63.73.23.23.13.23.32.8-3.13.2-3.63.33.1-3.33.3-2.6-2.63.13.13.02.52.53.1
Progressive ratio test 1 active lever presses6.17.69.5-2.8-3.0-2.9-2.8-2.9-2.9-2.7-2.6-2.93.0-2.92.9-3.1-2.83.1-3.13.03.0-2.4-2.4-2.2-3.1-1.70.0
Progressive ratio test 1 breakpoint5.97.29.4-2.8-2.9-2.9-2.7-2.8-2.8-2.7-2.5-2.93.0-2.82.8-3.0-2.73.0-3.03.03.0-2.3-2.3-2.1-3.1-1.50.0
Progressive ratio test 1 inactive lever presses0.40.61.6-0.6-0.9-0.6-0.8-0.8-0.8-0.7-0.8-0.70.7-0.61.0-1.2-0.61.2-1.20.70.8-0.3-0.3-0.8-0.8-0.70.0
Progressive ratio test 2 active lever presses1.11.31.9-1.1-1.2-1.3-1.2-1.2-1.2-1.1-1.0-1.01.4-1.31.1-1.2-1.21.2-1.21.31.3-0.8-0.8-0.6-1.3-0.50.0
Progressive ratio test 2 breakpoint1.01.11.7-1.1-1.2-1.3-1.1-1.1-1.2-1.1-1.0-1.01.3-1.21.0-1.2-1.11.2-1.21.21.2-0.7-0.7-0.6-1.2-0.50.0
Progressive ratio test 2 inactive lever presses0.40.62.1-0.8-0.7-0.7-0.5-0.6-0.7-0.5-0.4-0.70.8-0.81.0-1.1-0.61.1-1.10.80.9-0.7-0.70.1-1.50.30.0
Incentive Sensitization - Responses0.60.81.60.90.80.70.90.90.90.90.91.3-0.80.8-1.00.90.9-0.90.9-1.0-0.91.01.01.10.80.80.0
Incentive Sensitization - Breakpoint0.50.71.40.80.70.60.80.80.90.80.81.2-0.70.8-0.90.80.8-0.80.8-0.9-0.90.90.91.00.80.70.0
Sum of active levers in priming session hrs 5-60.10.10.3-0.5-0.3-0.3-0.4-0.3-0.3-0.4-0.4-0.10.3-0.40.5-0.4-0.30.4-0.40.30.3-0.6-0.6-0.3-0.3-0.30.0
Progressive ratio1.22.03.0-1.5-1.4-1.5-1.6-1.6-1.6-1.6-1.6-1.61.6-1.51.0-0.9-1.40.9-0.91.71.7-1.4-1.4-1.5-0.9-1.40.0
Food seeking constrained by brief footshock2.63.14.6-1.9-1.8-1.8-2.0-2.0-2.0-2.0-2.0-2.11.9-1.81.5-1.3-2.01.3-1.32.12.1-1.8-1.8-1.6-1.4-1.40.0
Seeking ratio, punishment vs. effort0.10.10.20.20.20.30.30.30.30.30.30.3-0.40.3-0.10.10.2-0.10.1-0.4-0.40.20.20.30.10.30.0
Retroperitoneal fat weight0.62.45.7-1.9-1.3-1.4-1.4-1.6-1.7-1.4-1.2-1.62.0-2.00.0-1.3-1.81.3-1.31.61.6-2.1-2.1-0.4-2.40.30.0
Reaction time number correct1.12.05.71.41.31.51.61.51.41.51.80.8-1.21.3-1.41.31.2-1.31.3-1.2-1.21.21.22.10.32.41.7
Reaction time mean minus median2.76.88.9-2.8-2.9-3.0-2.5-2.6-2.6-2.5-2.4-2.52.6-2.62.9-2.7-2.72.7-2.72.82.8-2.5-2.5-1.9-2.8-1.4-2.8
Reaction time mean minus median AUC1.94.86.2-2.3-2.5-2.4-2.2-2.2-2.2-2.2-2.1-2.12.2-2.22.4-2.2-2.32.2-2.22.12.1-2.1-2.1-1.9-2.1-1.5-2.3
Reaction time num false alarms1.62.33.6-1.6-1.9-1.6-1.5-1.5-1.4-1.5-1.5-1.51.3-1.31.7-1.7-1.21.7-1.71.31.3-1.5-1.5-1.6-1.2-1.7-1.3
Reaction time num false alarms AUC1.72.74.3-1.7-2.0-1.6-1.7-1.6-1.6-1.7-1.8-1.61.4-1.51.8-1.7-1.31.7-1.71.41.4-1.6-1.6-2.0-1.0-2.1-1.5
Reaction time trials correct on left1.12.05.71.41.31.51.61.51.41.51.80.8-1.21.3-1.41.31.2-1.31.3-1.2-1.21.21.22.10.32.41.7
Reaction time trials on left0.91.65.31.31.11.31.41.31.21.41.60.6-1.11.1-1.31.11.1-1.11.1-1.0-1.01.01.02.00.12.31.6
Reaction time mean0.60.91.6-1.1-1.1-1.2-0.8-0.8-0.9-0.8-0.7-0.70.9-0.91.1-1.1-1.01.1-1.11.11.1-1.0-1.0-0.4-1.3-0.1-1.0
Reaction time mean AUC0.30.61.1-0.9-1.0-0.9-0.6-0.6-0.6-0.6-0.5-0.50.7-0.70.9-0.8-0.70.8-0.80.80.8-0.8-0.8-0.2-1.00.1-0.8
Median of all reaction times0.00.10.3-0.3-0.2-0.30.00.0-0.00.10.10.10.1-0.10.3-0.3-0.10.3-0.30.20.2-0.3-0.30.4-0.50.5-0.2
Reaction time omissions7.310.612.8-3.5-3.3-3.1-3.3-3.3-3.4-3.3-3.2-3.43.3-3.43.6-3.2-3.43.2-3.23.33.3-3.4-3.4-2.7-3.2-2.3-3.3
Reaction time false alarm rate2.43.38.2-1.8-2.0-1.7-1.9-1.8-1.7-1.9-2.2-1.41.5-1.51.9-1.8-1.41.8-1.81.51.5-1.7-1.7-2.6-0.6-2.9-1.8
Reaction time premature initiation rate3.04.16.2-2.3-2.0-1.7-2.0-2.0-2.1-2.0-1.9-2.12.2-2.12.3-1.7-2.21.7-1.72.12.1-2.4-2.4-1.5-2.0-1.0-2.5
Reaction time premature initiations0.81.53.0-1.4-1.1-0.8-1.0-1.1-1.2-1.0-0.8-1.61.4-1.31.4-0.9-1.40.8-0.81.31.3-1.6-1.6-0.3-1.70.3-1.5
Std. dev. reaction times3.76.88.7-2.9-2.9-2.9-2.5-2.6-2.6-2.5-2.4-2.52.6-2.62.9-2.6-2.62.6-2.62.72.7-2.6-2.6-2.1-2.6-1.7-2.7
Reaction time trials completed0.91.65.31.31.11.31.41.31.21.41.60.6-1.11.1-1.31.11.1-1.11.1-1.0-1.01.01.02.00.12.31.6
Reaction time trials AUC1.32.56.11.61.51.61.71.61.51.71.91.0-1.41.4-1.61.41.4-1.41.4-1.4-1.41.41.42.20.52.52.0
Run reversals in cocaine runway, females0.50.51.20.90.70.90.80.80.70.90.90.5-0.70.8-0.60.50.8-0.50.5-0.4-0.40.80.81.10.11.00.0
Run reversals in cocaine runway, males0.60.61.2-0.7-0.8-0.7-0.8-0.8-0.8-0.9-0.9-0.60.6-0.61.0-1.1-0.71.1-1.10.50.5-0.5-0.5-0.7-0.3-1.00.0
Latency to leave start box in cocaine runway0.10.11.3-0.00.20.2-0.3-0.2-0.2-0.3-0.4-0.00.0-0.10.1-0.10.20.1-0.1-0.0-0.0-0.1-0.1-1.00.5-1.10.0
Latency to leave start box in cocaine runway, F1.01.13.4-0.9-0.7-0.8-1.3-1.2-1.2-1.3-1.4-1.00.9-1.01.0-1.0-0.81.0-1.00.90.9-0.8-0.8-1.7-0.2-1.80.0
Latency to leave start box in cocaine runway, M1.41.31.91.21.31.31.21.31.31.21.11.4-1.11.1-1.21.11.4-1.11.1-1.2-1.21.01.00.61.20.60.0
Std. dev. time between licks in bursts1.21.72.4-1.4-1.4-1.5-1.3-1.3-1.3-1.2-1.2-1.21.2-1.31.4-1.3-1.21.3-1.31.51.5-1.3-1.3-1.1-1.2-1.1-1.2
Total sessions with >9 infusions1.92.33.4-1.3-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.61.7-1.61.5-1.8-1.51.8-1.81.71.7-0.9-0.9-1.5-1.5-1.30.0
Short access day 1 total inactive lever presses1.31.72.5-1.2-1.5-1.3-1.3-1.4-1.4-1.3-1.3-1.31.4-1.31.3-1.6-1.31.6-1.61.41.4-0.8-0.8-1.4-1.4-0.80.0
Short access day 10 total inactive lever presses0.00.10.20.0-0.20.30.30.30.30.40.30.2-0.40.30.3-0.40.40.4-0.4-0.3-0.30.00.00.1-0.20.40.0
Short access day 1 total infusions0.81.12.6-1.1-1.3-1.2-1.0-1.1-1.1-1.0-0.8-1.11.4-1.30.9-1.2-1.21.2-1.21.21.2-0.6-0.6-0.4-1.60.00.0
Short access day 10 total infusions1.62.13.6-1.1-1.6-1.5-1.5-1.5-1.5-1.4-1.3-1.61.5-1.41.4-1.9-1.31.9-1.91.81.8-0.6-0.6-1.1-1.6-1.00.0
Short access total infusions2.73.45.8-1.8-2.2-1.9-1.8-1.9-2.0-1.8-1.6-1.92.2-2.01.8-2.2-1.92.2-2.22.12.1-1.2-1.2-1.2-2.4-0.60.0
Short access day 1 locomotion0.30.40.8-0.0-0.9-0.7-0.7-0.7-0.7-0.7-0.6-0.50.8-0.50.2-0.9-0.60.9-0.90.70.80.60.6-0.5-0.7-0.30.0
Short access day 10 total locomotion0.20.30.8-0.4-0.7-0.6-0.6-0.6-0.6-0.5-0.4-0.80.6-0.50.4-0.6-0.60.6-0.60.80.8-0.0-0.0-0.3-0.90.10.0
Short access total locomotion0.81.01.7-0.6-1.3-1.1-1.0-1.0-1.1-1.0-0.9-1.31.1-0.80.8-1.3-1.01.3-1.31.31.3-0.1-0.1-0.8-1.3-0.40.0
One hour access (0.3 mA shock)0.40.41.00.70.70.60.80.70.70.70.80.9-0.50.5-0.30.10.6-0.10.1-0.8-0.80.80.80.8-0.01.00.0
Compulsive drug intake0.30.41.00.70.80.70.60.60.70.50.50.8-0.70.6-0.30.20.6-0.20.2-1.0-1.00.70.70.20.70.20.0
One hour access (shock baseline)0.20.31.00.50.50.50.70.60.60.70.80.7-0.40.5-0.40.30.6-0.30.3-0.5-0.50.60.60.9-0.01.00.0
Social response proportion0.30.31.2-0.7-0.6-0.6-0.0-0.1-0.2-0.00.1-0.10.4-0.50.7-0.6-0.30.6-0.60.30.3-0.4-0.40.6-1.10.8-0.9
Social responses4.96.49.8-3.1-2.9-2.7-2.4-2.3-2.3-2.3-2.4-2.02.5-2.53.1-2.6-2.32.6-2.62.32.3-2.8-2.8-2.0-2.2-1.8-3.1
Social time0.40.62.30.40.80.90.90.90.80.91.00.4-0.70.7-0.50.70.7-0.70.7-0.5-0.50.20.21.4-0.01.50.2
Soleus weight1.03.04.01.91.92.01.71.71.71.71.71.7-1.71.8-2.01.91.5-1.91.9-1.5-1.51.71.71.81.51.71.9
Bone: stiffness17.728.835.85.95.65.65.55.65.65.55.45.3-5.55.5-6.05.25.6-5.25.2-5.0-5.05.65.64.74.73.95.5
Tibialis anterior weight2.99.924.53.23.13.02.62.83.02.41.94.0-3.23.2-3.43.33.0-3.33.3-4.2-4.23.13.10.64.9-0.32.8
Time to tail flick, vehicle, before self-admin1.51.54.3-1.7-1.1-0.9-1.1-1.1-1.1-1.1-1.1-1.20.9-1.21.6-1.1-1.21.1-1.11.11.1-2.1-2.1-1.1-1.1-1.00.0
Time to tail flick, vehicle, after self-admin0.30.41.00.90.91.00.50.50.50.50.40.6-0.60.6-0.70.80.4-0.80.8-0.7-0.70.70.70.20.80.10.0
Time to tail flick, test, before self-admin0.30.31.0-0.5-0.4-0.4-0.6-0.6-0.6-0.6-0.7-0.60.4-0.50.2-0.1-0.40.1-0.10.40.4-0.8-0.8-0.80.1-1.00.0
Time to tail flick, test, after self-admin1.01.01.61.21.01.11.01.01.01.11.00.8-1.21.3-1.21.11.0-1.11.1-0.8-0.81.01.00.90.80.60.0
Delta time to tail flick, vehicle, before/after SA0.90.81.91.21.00.90.90.80.80.80.91.0-0.70.8-1.00.70.7-0.70.7-0.9-0.91.41.41.10.61.10.0
Delta time to tail flick, test, before/after SA0.50.51.11.00.60.70.80.80.80.90.90.7-0.91.0-0.60.30.7-0.30.3-0.5-0.51.01.00.80.20.80.0
Tibia length4.311.818.73.33.23.23.93.83.73.94.13.6-3.43.4-3.43.03.4-3.03.0-3.1-3.13.23.24.32.04.33.2
Ambulatory time before self-admin2.02.94.6-1.8-2.2-2.1-1.9-1.9-1.9-1.9-1.8-1.91.8-1.71.6-1.7-1.91.7-1.71.71.7-1.4-1.4-1.7-1.4-1.20.0
Ambulatory time after self-admin1.82.15.3-1.8-1.8-1.7-1.2-1.2-1.3-1.1-0.9-1.61.4-1.51.7-1.7-1.51.7-1.71.51.5-1.5-1.5-0.3-2.30.20.0
Bone: tissue strength1.41.41.91.31.21.21.11.21.21.11.11.1-1.21.2-1.31.11.2-1.11.1-1.4-1.41.31.30.71.40.51.0
Total heroin consumption0.60.71.70.60.70.70.90.80.80.80.91.0-0.60.6-0.70.90.7-0.90.9-0.9-0.90.60.61.10.51.30.0
Bone: trabecular number3.45.68.42.62.22.12.62.52.42.62.82.1-2.32.3-2.62.22.3-2.22.2-1.8-1.82.42.42.91.42.82.5
Bone: trabecular spacing1.01.32.2-1.3-1.2-1.1-1.2-1.2-1.1-1.2-1.3-0.81.1-1.21.4-1.2-1.11.2-1.20.50.5-1.2-1.2-1.5-0.5-1.5-1.2
Bone: trabecular thickness0.30.40.80.70.40.30.60.60.60.50.50.5-0.70.8-0.70.40.7-0.40.4-0.7-0.70.80.80.30.60.10.9
Bone: trabecular tissue density0.60.92.81.00.60.50.50.70.80.60.20.9-1.21.2-0.80.41.3-0.40.4-0.5-0.51.31.3-0.91.6-1.71.1
Water consumed over 24 hours0.20.32.1-0.1-0.5-0.50.40.30.30.40.60.10.2-0.10.2-0.40.10.4-0.4-0.3-0.30.10.11.0-0.91.5-0.0
Number of responses in last shaping day0.10.10.60.5-0.3-0.0-0.1-0.00.0-0.0-0.1-0.1-0.20.3-0.2-0.30.10.3-0.30.10.10.80.8-0.60.1-0.50.0