Hub : Genes

Dgka

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio NM_080787.1 0.04 0.03 1.8e-03 0.01 0.02 0.01 0.01 6.7e-03 5.7e-03 9.7e-03 1.1e-02
2 Liver gene expression Dgka 0.3 0.13 0.0e+00 0.23 0.24 0.23 0.24 1.0e-24 5.6e-26 1.5e-25 3.4e-26
3 Liver mRNA stability Dgka 0.11 0.07 1.9e-10 0.09 0.08 0.08 0.09 6.6e-10 7.9e-09 2.3e-09 8.9e-10
4 Liver alternative polyA NM_080787.1 0.06 0.04 9.9e-06 0.04 0.04 0.04 0.04 1.9e-05 4.5e-05 5.6e-05 6.6e-05
5 Liver alternative polyA XM_039078319.1 0.12 0.08 2.5e-10 0.08 0.07 0.06 0.07 5.9e-09 2.1e-08 3.7e-07 2.7e-08
6 Liver alternative polyA NM_080787.1 0.06 0.04 2.5e-05 0.04 0.03 0.03 0.03 4.1e-05 1.1e-04 1.0e-04 1.2e-04
7 Liver alternative polyA XM_039078319.1 0.12 0.08 6.7e-10 0.07 0.07 0.06 0.07 9.8e-09 3.0e-08 1.4e-07 4.3e-08
8 Adipose gene expression Dgka 0.25 0.12 0.0e+00 0.15 0.17 0.17 0.17 1.7e-16 1.1e-18 3.5e-18 7.5e-19
9 IL gene expression Dgka 0.26 0.16 1.4e-03 0.07 0.05 0.07 0.06 9.2e-03 2.6e-02 1.1e-02 1.2e-02
10 Brain intron excision ratio chr7_1150002_1150864 0.04 0.04 5.0e-03 0.03 0.02 0.02 0.03 9.1e-04 9.4e-03 7.5e-03 1.8e-03
11 Brain gene expression Dgka 0.05 0.04 1.9e-03 0.03 0.02 0.02 0.02 1.1e-03 5.1e-03 3.9e-03 3.7e-03
12 Adipose alternative polyA XM_039078319.1 0.1 0.07 1.1e-08 0.07 0.07 0.07 0.07 1.4e-08 7.0e-08 4.6e-08 3.2e-08
13 Adipose alternative polyA XM_039078319.1 0.13 0.08 8.8e-12 0.1 0.09 0.1 0.1 3.1e-11 1.4e-10 6.8e-11 5.8e-11
14 Adipose isoform ratio XM_039078319.1 0.1 0.07 1.8e-08 0.07 0.06 0.06 0.06 5.4e-08 4.8e-07 2.1e-07 2.6e-07
15 LHb mRNA stability Dgka 0.2 0.15 2.2e-03 0.14 0.1 0.08 0.11 3.9e-04 2.0e-03 6.9e-03 1.5e-03
16 PL mRNA stability Dgka 0.05 0.04 1.2e-03 0.03 0.01 0.02 0.02 2.9e-04 9.6e-03 4.0e-03 4.5e-03
17 Adipose mRNA stability Dgka 0.11 0.07 2.3e-11 0.08 0.08 0.09 0.08 3.2e-09 1.7e-09 8.0e-10 1.6e-09
18 BLA gene expression Dgka 0.12 0.08 4.2e-06 0.11 0.11 0.11 0.1 1.6e-06 2.4e-06 1.5e-06 6.5e-06
19 RMTg alternative polyA XM_039078319.1 0.18 0.11 8.6e-04 0.04 0.05 0.04 0.03 3.3e-02 1.6e-02 2.8e-02 4.6e-02
20 Adipose alternative polyA NM_080787.1 0.03 0.02 1.2e-03 0.01 0.02 0.01 0.01 2.6e-02 5.3e-03 3.3e-02 1.5e-02
21 Adipose alternative polyA NM_080787.1 0.04 0.03 8.8e-05 0.02 0.03 0.03 0.03 3.3e-03 2.4e-04 4.1e-04 5.4e-04
22 PL gene expression Dgka 0.14 0.08 0.0e+00 0.1 0.16 0.14 0.15 2.9e-11 4.2e-17 1.1e-15 9.2e-16

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.01.65.0-0.5-0.41.01.0-1.01.0-1.0-0.5-0.9-0.9-0.8-1.1-1.1-1.11.1-0.81.7-1.71.9-1.9-1.92.2
Area under the delay curve0.10.10.40.2-0.00.10.3-0.30.3-0.30.2-0.1-0.6-0.20.30.30.3-0.40.1-0.2-0.40.1-0.1-0.20.2
BMI with tail6.721.727.45.25.2-5.0-4.94.9-4.94.95.24.9-5.2-5.24.84.84.8-4.7-5.1-4.13.8-3.83.73.6-3.0
BMI without tail1.73.43.92.01.9-2.0-1.91.9-1.91.91.91.9-1.7-1.71.91.91.9-1.9-1.6-1.81.8-1.81.81.7-1.6
Body weight1.35.37.12.62.4-2.2-2.22.2-2.22.22.62.2-2.7-2.32.62.62.6-2.6-2.3-2.32.0-2.02.01.9-1.7
Weight adjusted by age0.10.10.30.10.1-0.3-0.30.3-0.30.30.10.30.30.20.20.20.2-0.20.2-0.40.4-0.50.50.5-0.6
Bone surface2.74.712.7-1.3-0.91.81.8-1.81.8-1.8-1.2-1.8-0.5-0.9-2.2-2.2-2.22.2-0.93.0-2.83.1-3.1-3.23.6
Bone volume2.33.911.5-1.0-0.71.61.6-1.61.6-1.6-0.9-1.6-0.9-1.1-1.9-1.9-1.91.9-1.12.7-2.62.9-2.9-3.03.4
Breakpoint value in progressive ratio session1.41.64.1-1.5-1.51.31.3-1.31.3-1.3-1.4-1.32.01.7-1.2-1.2-1.21.21.70.8-0.70.7-0.7-0.70.4
Number of licking bursts4.04.75.22.32.2-2.3-2.32.3-2.32.32.22.3-1.8-1.72.32.32.3-2.3-1.7-2.22.2-2.22.22.2-2.0
Context. condit. distance diff. score0.30.30.40.60.6-0.6-0.60.6-0.60.60.60.6-0.4-0.50.60.60.6-0.6-0.5-0.60.4-0.50.50.5-0.5
Locomotion velocity, session 10.20.20.80.1-0.10.40.4-0.40.4-0.40.1-0.4-0.9-0.5-0.0-0.0-0.00.0-0.50.5-0.60.7-0.7-0.80.9
Locomotion distance, session 10.81.12.5-0.7-0.71.01.0-1.01.0-1.0-0.6-1.0-0.1-0.1-0.9-0.9-0.90.9-0.11.3-1.41.4-1.5-1.51.6
Locomotion velocity, session 22.63.15.2-1.6-1.41.71.7-1.71.7-1.7-1.5-1.70.80.5-1.9-1.9-1.91.90.52.2-2.12.2-2.2-2.22.3
Locomotion distance, session 23.85.26.9-2.1-2.22.52.5-2.52.5-2.5-2.1-2.51.01.4-2.2-2.2-2.22.21.42.4-2.62.6-2.6-2.62.5
Locomotion velocity, session 34.04.76.3-2.4-2.52.32.3-2.32.3-2.3-2.4-2.32.42.5-2.2-2.2-2.22.22.51.8-1.81.7-1.7-1.61.3
Locomotion distance, session 30.00.00.1-0.2-0.30.20.2-0.20.2-0.2-0.2-0.20.20.4-0.1-0.1-0.10.10.4-0.00.0-0.10.10.1-0.2
Stereotopy head waving bouts, day 36.17.18.4-2.9-2.82.72.7-2.72.7-2.7-2.9-2.72.62.5-2.9-2.9-2.92.92.52.6-2.42.4-2.4-2.42.1
Stereotopy head waving duration, day 34.14.96.8-2.5-2.12.12.1-2.12.1-2.1-2.4-2.12.41.9-2.6-2.6-2.62.61.92.3-1.92.1-2.0-2.01.8
Locomotion velocity, session 70.20.20.3-0.4-0.30.40.4-0.40.4-0.4-0.3-0.40.30.1-0.4-0.4-0.40.40.10.5-0.60.6-0.6-0.60.6
Locomotion distance, session 70.30.40.80.40.4-0.6-0.60.6-0.60.60.40.60.0-0.10.60.60.6-0.6-0.1-0.70.8-0.80.80.8-0.9
Stereotopy head waving bouts, day 71.51.62.3-1.1-1.21.41.4-1.41.4-1.4-1.1-1.40.50.7-1.2-1.2-1.21.20.71.4-1.51.5-1.5-1.51.5
Stereotopy head waving duration, day 71.41.62.6-1.0-1.21.41.4-1.41.4-1.4-1.0-1.40.20.6-1.1-1.1-1.11.10.61.4-1.61.6-1.6-1.61.6
Locomotion velocity, session 82.32.84.3-1.4-1.51.81.8-1.81.8-1.8-1.4-1.80.30.8-1.5-1.5-1.51.50.81.8-2.12.0-2.0-2.12.0
Locomotion distance, session 80.40.60.9-0.7-0.80.90.9-0.90.9-0.9-0.7-0.90.30.6-0.6-0.6-0.60.60.60.7-1.00.8-0.8-0.80.7
Degree of sensitization distance0.50.50.70.70.8-0.7-0.70.7-0.70.70.80.7-0.7-0.80.70.70.7-0.7-0.8-0.60.5-0.50.50.5-0.3
Degree of sensitization stereotypy0.10.10.60.20.00.20.2-0.20.2-0.20.2-0.2-0.8-0.40.20.20.2-0.2-0.40.2-0.40.4-0.4-0.40.5
Conditioned locomotion2.02.33.51.41.2-1.5-1.51.5-1.51.51.31.5-0.7-0.51.61.61.6-1.7-0.5-1.81.9-1.81.81.8-1.9
Cocaine response after cond. corrected3.33.74.61.91.8-2.1-2.12.1-2.12.11.82.0-1.2-1.22.02.02.0-2.0-1.2-2.02.1-2.12.12.1-2.1
Cocaine response after cond. not corrected3.64.05.11.91.9-2.1-2.12.1-2.12.11.82.1-1.1-1.22.02.02.0-2.0-1.2-2.22.3-2.22.22.2-2.2
Cocaine response before conditioning0.60.81.0-0.9-0.90.90.9-0.90.9-0.9-0.9-1.00.80.7-0.9-0.9-0.90.90.70.8-0.80.8-0.8-0.80.8
Saline control response0.50.70.80.80.8-0.8-0.80.8-0.80.80.80.7-0.8-0.60.90.90.9-0.9-0.6-0.90.9-0.80.80.8-0.8
Bone: connectivity density0.61.03.0-0.5-0.30.80.8-0.80.8-0.8-0.4-0.7-0.6-0.6-0.9-0.9-0.90.9-0.61.4-1.31.4-1.5-1.51.7
Bone: cortical apparent density1.31.72.41.41.5-1.5-1.51.5-1.51.51.41.4-1.3-1.51.21.21.2-1.2-1.5-1.11.1-1.01.01.0-0.8
Bone: cortical area0.40.63.20.71.0-0.5-0.50.5-0.50.50.80.5-1.3-1.80.10.10.1-0.1-1.80.4-0.20.4-0.5-0.50.9
Bone: cortical porosity0.20.20.6-0.4-0.10.30.3-0.30.3-0.3-0.3-0.20.2-0.2-0.6-0.6-0.60.6-0.20.7-0.60.7-0.7-0.70.8
Bone: cortical porosity0.20.20.8-0.10.20.10.1-0.10.1-0.1-0.00.1-0.4-0.8-0.5-0.5-0.50.5-0.80.7-0.50.7-0.7-0.70.9
Bone: cortical thickness0.81.33.81.31.5-1.2-1.21.2-1.21.21.41.2-1.5-1.90.90.90.9-0.9-1.9-0.50.7-0.50.50.4-0.1
Bone: cortical thickness1.11.21.61.11.1-1.2-1.21.2-1.21.21.11.3-0.8-0.91.21.21.2-1.2-0.9-1.11.1-1.11.11.1-1.0
Bone: cortical tissue density1.01.31.71.21.3-1.3-1.31.3-1.31.31.21.2-1.1-1.31.11.11.1-1.0-1.3-0.90.9-0.90.90.9-0.8
Condit. Reinf. active minus inactive responses2.02.22.9-1.7-1.51.41.4-1.41.4-1.4-1.6-1.41.71.4-1.6-1.6-1.61.61.41.4-1.51.4-1.4-1.31.2
Condit. Reinf. active-inactive response ratio0.20.20.9-0.5-0.40.20.2-0.20.2-0.2-0.5-0.21.00.6-0.5-0.5-0.50.50.60.3-0.10.1-0.1-0.10.0
Condit. Reinf. active responses3.54.35.0-2.2-2.02.12.1-2.12.1-2.1-2.1-2.11.81.5-2.2-2.2-2.22.21.52.2-2.22.2-2.2-2.12.0
Condit. Reinf. inactive responses2.22.73.6-1.5-1.51.71.7-1.71.7-1.7-1.5-1.70.91.0-1.6-1.6-1.61.61.01.8-1.91.9-1.9-1.91.8
Incentive salience index mean1.72.13.0-1.5-1.41.51.5-1.51.5-1.5-1.4-1.51.10.9-1.5-1.5-1.51.50.91.5-1.71.6-1.6-1.61.6
Condit. Reinf. lever presses1.01.43.3-0.7-0.81.21.2-1.21.2-1.2-0.7-1.2-0.30.0-0.9-0.9-0.90.90.01.3-1.81.6-1.7-1.71.8
Condit. Reinf. active minus inactive responses1.31.64.7-1.5-1.41.11.1-1.11.1-1.1-1.6-1.02.21.8-1.4-1.4-1.41.41.80.8-0.50.6-0.5-0.50.2
Condit. Reinf. active-inactive response ratio0.40.41.7-0.4-0.50.10.1-0.10.1-0.1-0.50.01.31.2-0.0-0.0-0.00.01.2-0.50.6-0.60.70.7-0.9
Condit. Reinf. active responses1.31.83.2-1.6-1.31.21.2-1.21.2-1.2-1.6-1.21.81.4-1.7-1.7-1.71.71.41.3-0.81.1-1.0-1.00.9
Condit. Reinf. inactive responses0.70.81.4-0.9-0.70.80.8-0.80.8-0.8-0.9-0.90.50.3-1.1-1.1-1.11.10.31.2-0.81.0-1.1-1.11.1
Condit. Reinf. lever presses2.02.74.9-1.9-1.81.51.5-1.51.5-1.5-2.0-1.52.22.2-1.8-1.8-1.81.82.21.3-0.81.0-0.9-0.90.6
Condit. Reinf. lever reinforcers received0.81.22.7-1.3-1.10.90.9-0.90.9-0.9-1.3-0.91.61.3-1.3-1.3-1.31.31.31.0-0.50.7-0.7-0.60.5
Conditioned reinforcement - actives0.50.51.3-0.5-0.10.30.3-0.30.3-0.3-0.5-0.30.3-0.3-1.1-1.1-1.11.1-0.31.1-0.50.8-0.8-0.81.0
Conditioned reinforcement - inactives1.61.83.01.11.5-1.7-1.71.7-1.71.71.11.7-0.1-1.00.90.90.9-0.9-1.0-1.11.7-1.41.41.4-1.3
Conditioned locomotion3.13.86.3-2.2-1.61.61.6-1.61.6-1.6-2.1-1.62.51.5-2.5-2.5-2.52.51.52.2-1.51.8-1.8-1.71.7
Patch foraging indifference point 0 sec2.84.47.92.32.6-2.3-2.32.3-2.32.32.42.4-2.4-2.82.02.02.0-1.9-2.8-1.51.6-1.51.41.4-1.0
Patch foraging indifference point AUC0.40.40.9-0.8-0.90.80.8-0.80.8-0.8-0.7-0.90.60.9-0.4-0.4-0.40.50.90.4-0.60.5-0.5-0.50.3
Delay disc. indifference point, 0s delay0.70.74.41.00.8-0.4-0.30.3-0.30.31.10.4-2.1-1.60.80.80.8-0.8-1.4-0.1-0.60.4-0.4-0.40.7
Delay disc. indifference point, 16s delay0.30.30.6-0.4-0.60.60.7-0.70.7-0.7-0.4-0.60.40.5-0.3-0.3-0.30.30.70.3-0.80.4-0.4-0.40.3
Delay disc. indifference point, 2s delay0.10.21.10.40.3-0.10.0-0.00.0-0.00.50.1-1.0-0.60.50.50.5-0.5-0.5-0.00.10.2-0.2-0.20.3
Delay disc. indifference point, 24s delay0.30.30.80.70.4-0.3-0.20.2-0.20.20.70.3-0.9-0.40.90.90.9-0.9-0.3-0.7-0.0-0.40.40.3-0.3
Delay disc. indifference point, 4s delay0.80.81.3-0.7-0.81.01.0-1.01.0-1.0-0.7-1.0-0.00.3-0.8-0.8-0.80.70.51.0-1.11.1-1.1-1.11.1
Delay disc. indifference point, 8s delay0.30.40.90.50.3-0.5-0.30.3-0.30.30.50.5-0.5-0.00.80.80.8-0.80.2-0.90.3-0.70.70.7-0.8
Indifference point function ln k0.10.20.40.40.6-0.6-0.50.5-0.50.50.40.6-0.0-0.60.20.20.2-0.2-0.6-0.20.6-0.30.30.3-0.2
Indifference point function log k0.10.20.40.40.6-0.6-0.50.5-0.50.50.40.6-0.0-0.60.20.20.2-0.2-0.6-0.20.6-0.30.30.3-0.2
Patch foraging total patch changes 0 sec2.74.37.12.32.5-2.3-2.22.2-2.22.22.32.3-2.2-2.71.91.91.9-1.9-2.6-1.61.7-1.51.51.4-1.1
Patch foraging total patch changes 12 sec2.12.73.21.71.7-1.8-1.81.8-1.81.81.71.8-1.4-1.41.71.71.7-1.7-1.4-1.61.6-1.61.61.6-1.5
Patch foraging total patch changes 18 sec0.00.10.20.20.1-0.1-0.10.1-0.10.10.30.1-0.2-0.10.40.40.4-0.4-0.1-0.40.0-0.20.20.2-0.2
Patch foraging total patch changes 24 sec0.40.51.20.80.7-0.6-0.60.6-0.60.60.90.6-1.1-0.90.80.80.8-0.9-0.9-0.60.3-0.40.40.4-0.3
Patch foraging total patch changes 6 sec1.62.33.61.71.9-1.7-1.71.7-1.71.71.71.7-1.6-1.91.41.41.4-1.4-1.9-1.11.3-1.11.11.1-0.8
Patch foraging time to switch 0 sec0.10.11.10.50.4-0.2-0.20.2-0.20.20.40.3-1.1-0.70.10.10.1-0.3-0.70.2-0.30.2-0.2-0.20.4
Patch foraging water rate 0 sec0.91.52.41.01.1-1.3-1.31.3-1.31.31.11.2-0.3-0.71.31.31.3-1.1-0.7-1.41.5-1.41.41.4-1.4
Patch foraging water rate 12 sec1.32.03.31.31.3-1.5-1.51.5-1.51.51.31.5-0.4-0.81.41.41.4-1.4-0.8-1.61.8-1.61.61.6-1.6
Patch foraging water rate 18 sec0.91.33.70.40.4-0.9-1.01.0-1.01.00.41.00.90.50.90.90.9-0.80.5-1.51.7-1.61.71.7-1.9
Patch foraging water rate 24 sec3.65.09.21.81.7-2.2-2.22.2-2.22.21.82.2-0.3-0.52.32.32.3-2.3-0.5-2.83.0-2.92.92.9-3.0
Patch foraging water rate 6 sec0.30.42.7-0.5-0.3-0.1-0.10.1-0.10.1-0.40.01.61.0-0.1-0.1-0.10.20.9-0.50.8-0.60.70.7-0.9
Seeking ratio, delayed vs. immediate footshock1.92.23.3-1.5-1.31.41.4-1.41.4-1.4-1.5-1.41.30.9-1.8-1.8-1.81.80.81.7-1.31.5-1.5-1.51.5
Distance traveled before self-admin0.90.91.3-1.1-1.11.11.1-1.11.1-1.1-1.0-1.10.91.0-0.8-0.8-0.80.81.00.8-0.80.9-0.9-0.90.7
Distance traveled after self-admin0.30.30.5-0.6-0.50.60.6-0.60.6-0.6-0.6-0.60.40.3-0.7-0.7-0.70.70.40.7-0.50.6-0.6-0.60.6
Extensor digitorum longus weight5.923.426.55.25.1-5.1-5.15.1-5.15.15.15.1-4.6-4.35.05.05.0-5.0-4.3-4.74.5-4.64.54.5-4.0
Bone: elastic displacement0.00.00.1-0.1-0.10.10.1-0.10.1-0.1-0.1-0.10.2-0.1-0.3-0.3-0.30.2-0.10.3-0.20.2-0.3-0.30.3
Bone: elastic work0.30.41.30.80.8-0.5-0.50.5-0.50.50.70.6-1.1-1.10.50.50.5-0.5-1.1-0.10.2-0.10.10.10.1
Bone: endosteal estimation0.30.62.60.81.1-0.8-0.80.8-0.80.80.90.7-1.1-1.60.40.40.4-0.4-1.6-0.10.3-0.10.10.00.2
Bone: endosteal perimeter0.61.32.5-1.0-0.71.01.1-1.11.1-1.1-0.9-0.90.50.1-1.4-1.4-1.41.40.11.6-1.31.4-1.5-1.51.6
Epididymis fat weight0.00.10.4-0.2-0.40.30.3-0.30.3-0.3-0.2-0.30.40.60.00.00.0-0.00.6-0.20.0-0.10.10.1-0.3
Delta time in closed arm before/after self-admin2.62.54.81.11.3-1.7-1.71.7-1.71.71.11.70.1-0.31.41.41.4-1.4-0.3-1.82.1-2.12.12.1-2.2
Delta time in open arm before/after self-admin1.21.23.11.31.0-0.8-0.80.8-0.80.81.30.8-1.8-1.21.41.41.4-1.4-1.2-1.10.6-0.70.70.6-0.5
Diff in mean of infusions in LGA sessions1.82.03.5-1.6-1.51.41.4-1.41.4-1.4-1.6-1.41.91.6-1.5-1.5-1.51.51.61.2-1.01.1-1.1-1.00.8
Delay discount exponential model param0.10.10.3-0.20.1-0.2-0.30.3-0.30.3-0.20.20.50.1-0.3-0.3-0.30.3-0.20.20.4-0.10.10.1-0.1
Extinction: sum of active levers before priming1.51.55.0-1.4-1.61.21.2-1.21.2-1.2-1.5-1.21.92.2-0.9-0.9-0.90.92.20.4-0.60.4-0.3-0.3-0.1
Active lever presses in extinction session 61.21.21.7-1.1-1.31.31.3-1.31.3-1.3-1.1-1.20.81.1-0.9-0.9-0.90.91.10.8-1.11.0-1.0-1.00.8
Bone: final force1.42.36.51.81.9-1.4-1.41.4-1.41.41.81.5-2.5-2.51.31.31.3-1.3-2.5-0.70.8-0.60.50.5-0.1
Bone: final moment1.32.26.31.81.8-1.4-1.31.3-1.31.31.81.5-2.5-2.51.31.31.3-1.2-2.5-0.60.7-0.50.50.4-0.0
Food consumed during 24 hour testing period0.30.40.70.70.7-0.7-0.70.7-0.70.70.70.7-0.8-0.70.60.60.6-0.6-0.7-0.40.6-0.40.40.4-0.3
Glucose1.82.83.61.91.8-1.7-1.71.7-1.71.71.91.7-1.7-1.71.81.81.8-1.9-1.7-1.61.4-1.41.41.4-1.2
Heart weight0.10.10.20.10.3-0.4-0.40.4-0.40.40.20.30.2-0.10.20.20.2-0.2-0.1-0.30.3-0.40.40.4-0.4
Delay discount hyperbolic model param0.10.10.6-0.3-0.1-0.0-0.20.2-0.20.2-0.40.00.70.3-0.4-0.4-0.40.50.00.20.2-0.10.10.1-0.1
Intermittent access intake day 1-15 change0.30.32.1-0.7-0.30.20.2-0.20.2-0.2-0.7-0.21.50.4-0.9-0.9-0.90.90.40.50.00.2-0.2-0.20.2
Intermittent access intake escalation0.30.32.2-0.20.1-0.4-0.40.4-0.40.4-0.30.41.50.5-0.2-0.2-0.20.20.5-0.30.8-0.60.70.7-0.8
Intermittent access intake escalation 20.40.43.2-0.7-0.50.10.1-0.10.1-0.1-0.7-0.11.81.0-0.5-0.5-0.50.61.0-0.00.3-0.20.30.3-0.5
Intermitt. access day 1 inactive lever presses0.30.31.3-0.10.2-0.5-0.50.5-0.50.5-0.10.51.20.5-0.0-0.0-0.00.00.5-0.40.8-0.70.70.8-0.8
Intermitt. access day 15 inactive lever presses0.40.53.1-0.8-0.70.40.4-0.40.4-0.4-0.9-0.41.71.2-0.7-0.7-0.70.81.20.20.00.00.00.0-0.2
Intermitt. access escalation Index1.00.92.1-0.6-0.30.60.6-0.60.6-0.6-0.7-0.60.1-0.4-1.2-1.2-1.21.3-0.41.4-1.01.2-1.2-1.31.5
Intermittent access day 1 total infusions0.20.20.70.50.6-0.5-0.50.5-0.50.50.50.5-0.8-0.80.20.20.2-0.2-0.8-0.10.2-0.10.10.10.1
Intermittent access day 15 total infusions0.20.20.40.30.6-0.6-0.60.6-0.60.60.20.60.2-0.40.00.00.00.1-0.4-0.20.6-0.40.40.4-0.3
Intermittent access terminal intake (last 3 days)0.10.10.60.10.5-0.3-0.30.3-0.30.30.10.3-0.0-0.8-0.3-0.3-0.30.4-0.80.30.10.1-0.2-0.20.3
Intermittent access total infusions0.30.30.60.60.8-0.7-0.70.7-0.70.70.50.7-0.4-0.80.30.30.3-0.2-0.8-0.30.5-0.40.40.4-0.3
Intermittent access day 1 locomotion0.00.00.00.10.1-0.1-0.10.1-0.10.10.00.1-0.10.00.00.00.0-0.00.0-0.00.0-0.10.10.1-0.1
Intermittent access day 15 total locomotion0.40.42.0-0.8-0.40.30.3-0.30.3-0.3-0.7-0.31.40.5-0.9-0.9-0.90.90.50.6-0.00.3-0.3-0.30.3
Intermittent access total locomotion0.30.30.5-0.6-0.50.50.5-0.50.5-0.5-0.6-0.50.60.4-0.7-0.7-0.70.70.40.6-0.40.5-0.5-0.50.5
Intermittent access standard deviation0.20.21.6-0.5-0.1-0.0-0.00.0-0.00.0-0.50.01.30.3-0.6-0.6-0.60.70.30.30.20.0-0.00.00.0
Left kidney weight0.10.31.20.10.10.30.3-0.30.3-0.30.1-0.2-0.8-0.8-0.2-0.2-0.20.2-0.80.7-0.70.9-0.9-0.91.1
Right kidney weight0.41.21.9-1.1-0.80.91.0-1.01.0-1.0-1.0-0.90.80.4-1.2-1.2-1.21.30.41.4-1.21.3-1.3-1.31.3
Cocaine induced anxiety2.22.63.5-1.5-1.61.81.8-1.81.8-1.8-1.5-1.80.81.1-1.5-1.5-1.51.51.11.7-1.91.8-1.8-1.81.7
Post-drug Anxiety1.41.53.2-0.9-0.91.21.2-1.21.2-1.2-0.8-1.2-0.20.1-1.1-1.1-1.11.10.11.5-1.71.7-1.7-1.71.8
Baseline Anxiety0.10.10.20.20.2-0.2-0.20.2-0.20.20.20.20.0-0.00.30.30.3-0.3-0.0-0.40.5-0.40.40.4-0.5
Tail length3.310.117.6-3.6-3.83.43.4-3.43.4-3.4-3.7-3.44.04.2-3.1-3.1-3.13.14.12.3-2.12.1-2.1-2.01.4
Length with tail1.45.17.2-2.4-2.72.62.5-2.52.5-2.5-2.5-2.52.32.6-2.1-2.1-2.12.12.51.8-1.81.9-1.8-1.81.5
Length without tail0.10.10.70.20.20.10.1-0.10.1-0.10.2-0.0-0.8-0.60.10.10.1-0.1-0.70.3-0.40.5-0.5-0.50.7
Times rat made contact with spout1.51.72.11.31.2-1.3-1.31.3-1.31.31.31.3-1.0-0.91.51.51.5-1.4-0.9-1.51.3-1.41.31.3-1.3
Lifetime Intake0.50.62.00.81.1-0.9-0.90.9-0.90.90.80.9-0.8-1.40.30.30.3-0.3-1.4-0.20.6-0.40.40.3-0.1
Liver weight, left1.62.63.61.71.8-1.8-1.81.8-1.81.81.71.9-1.3-1.51.51.51.5-1.6-1.5-1.41.5-1.51.51.5-1.3
Liver weight, right0.71.11.81.21.3-1.2-1.21.2-1.21.21.21.2-1.0-1.31.01.01.0-1.0-1.3-0.80.9-0.80.80.7-0.5
Locomotor activity3.65.77.0-2.4-2.62.72.6-2.62.6-2.6-2.4-2.51.92.1-2.4-2.4-2.42.42.12.3-2.42.4-2.3-2.32.1
Locomotor testing distance1.52.42.9-1.6-1.61.61.6-1.61.6-1.6-1.6-1.51.31.3-1.7-1.7-1.71.61.31.6-1.51.6-1.5-1.51.4
Locomotor testing rearing0.00.00.20.1-0.0-0.1-0.10.1-0.10.10.00.20.10.20.20.20.2-0.20.3-0.30.3-0.30.30.3-0.4
Locomotion in novel chamber0.20.20.30.40.6-0.6-0.60.6-0.60.60.40.6-0.2-0.60.30.30.3-0.3-0.6-0.20.5-0.30.30.3-0.2
Locomotion in novel chamber post-restriction3.03.64.9-2.1-2.22.12.1-2.12.1-2.1-2.1-2.12.12.2-1.8-1.8-1.81.82.11.6-1.41.5-1.4-1.41.1
Fecal boli incidents, locomotor time 11.31.52.31.20.9-1.1-1.11.1-1.11.11.11.1-0.7-0.41.41.41.4-1.4-0.4-1.51.5-1.51.51.5-1.5
Change in fecal boli incidents, locomotor task1.31.32.4-0.9-0.91.11.0-1.01.0-1.0-0.9-1.10.30.3-1.2-1.2-1.21.10.01.4-1.51.5-1.5-1.51.5
Time >=10cm from walls, locomotor time 10.20.21.10.60.6-0.3-0.30.3-0.30.30.60.3-1.1-1.10.30.30.3-0.3-0.90.1-0.20.2-0.2-0.30.5
Bouts of movement, locomotor time 10.40.41.0-0.7-0.60.60.7-0.70.7-0.7-0.7-0.60.80.7-0.7-0.7-0.70.71.00.4-0.50.4-0.4-0.40.3
Total resting periods, locomotor time 11.01.11.9-1.2-1.11.11.2-1.21.2-1.2-1.1-1.11.11.1-1.1-1.1-1.11.11.40.9-0.90.8-0.8-0.80.6
Rest time, locomotor task time 10.60.60.9-0.7-0.80.90.9-0.90.9-0.9-0.7-0.90.40.6-0.7-0.7-0.70.70.80.7-0.90.8-0.8-0.80.7
Distance moved, locomotor task time 10.30.32.00.60.7-0.4-0.60.6-0.60.60.60.4-0.9-1.10.20.20.2-0.2-1.40.2-0.20.2-0.2-0.30.5
Vertical activity count, locomotor time 11.21.21.91.11.3-1.3-1.41.4-1.41.41.11.3-0.7-1.20.90.90.9-0.9-1.3-0.91.0-0.90.90.9-0.8
Time >=10cm from walls, locomotor time 21.31.41.81.21.3-1.3-1.31.3-1.31.31.21.3-0.8-1.01.21.21.2-1.1-0.9-1.11.3-1.21.21.2-1.1
Bouts of movement, locomotor time 20.80.92.1-0.7-0.70.91.1-1.11.1-1.1-0.7-0.90.20.2-0.9-0.9-0.90.90.61.0-1.41.2-1.2-1.21.2
Total resting periods, locomotor time 20.91.02.3-0.7-0.60.91.1-1.11.1-1.1-0.7-0.90.10.1-0.9-0.9-0.90.90.41.1-1.51.2-1.3-1.31.3
Rest time, locomotor task time 20.30.30.7-0.3-0.40.50.6-0.60.6-0.6-0.3-0.5-0.2-0.0-0.4-0.4-0.40.40.00.7-0.80.7-0.8-0.80.8
Distance moved, locomotor task time 20.30.30.70.30.4-0.5-0.60.6-0.60.60.30.50.20.00.40.40.4-0.4-0.1-0.70.7-0.80.80.8-0.8
Vertical activity count, locomotor time 22.32.53.21.51.5-1.7-1.71.7-1.71.71.41.7-0.8-0.91.61.61.6-1.5-0.9-1.81.6-1.81.81.8-1.8
Light reinforcement 13.36.18.6-2.7-2.62.62.6-2.62.6-2.6-2.6-2.62.92.4-2.6-2.6-2.62.62.42.2-2.02.1-2.1-2.11.8
Light reinforcement 20.91.21.9-1.2-1.11.11.1-1.11.1-1.1-1.2-1.11.41.1-1.2-1.2-1.21.21.11.0-0.90.9-0.9-0.90.7
Bone: marrow area0.20.52.30.81.1-0.8-0.70.7-0.70.70.80.7-1.0-1.50.40.40.4-0.4-1.5-0.00.3-0.10.10.00.2
Bone: maximum diameter1.01.83.8-1.1-0.71.11.1-1.11.1-1.1-1.0-1.20.5-0.1-1.6-1.6-1.61.6-0.01.8-1.51.8-1.8-1.81.9
Bone: maximum force1.62.87.22.02.1-1.6-1.61.6-1.61.62.01.7-2.6-2.71.51.51.5-1.5-2.7-0.81.0-0.80.70.7-0.3
Bone: maximum moment1.52.77.12.02.0-1.6-1.61.6-1.61.61.91.7-2.5-2.71.41.41.4-1.4-2.6-0.81.0-0.70.70.6-0.2
Mean time between licks in bursts0.60.82.1-1.1-0.90.70.7-0.70.7-0.7-1.1-0.71.41.1-1.1-1.1-1.11.21.10.9-0.40.5-0.5-0.50.3
Mean num. licks in bursts0.81.01.2-1.1-1.11.11.1-1.11.1-1.1-1.0-1.10.90.9-1.0-1.0-1.01.00.90.9-1.01.0-1.0-0.90.9
Cd content in liver0.30.30.60.60.8-0.7-0.60.6-0.60.60.60.5-0.7-0.70.60.60.6-0.4-0.6-0.3-0.0-0.30.30.3-0.2
Co content in liver0.70.82.0-1.1-1.00.70.8-0.80.8-0.8-1.1-0.81.41.2-1.0-1.0-1.01.01.30.6-0.50.4-0.4-0.40.2
Cu content in liver0.50.62.80.71.1-0.8-0.70.7-0.70.70.90.7-1.0-1.70.40.40.4-0.3-1.60.1-0.10.2-0.2-0.30.6
Fe content in liver0.70.81.20.80.8-0.9-1.01.0-1.01.00.81.0-0.6-0.60.80.80.8-0.8-0.6-0.91.1-1.01.01.0-1.0
K content in liver1.21.11.7-1.0-0.80.91.1-1.11.1-1.1-0.9-1.10.50.3-1.2-1.2-1.21.20.51.3-1.21.3-1.3-1.31.3
Mg content in liver1.01.02.0-0.8-0.70.91.1-1.11.1-1.1-0.7-1.1-0.10.1-1.0-1.0-1.00.90.31.2-1.41.3-1.3-1.31.4
Mn content in liver2.32.76.0-1.2-1.01.51.5-1.51.5-1.5-1.1-1.5-0.0-0.1-1.6-1.6-1.61.6-0.12.1-2.12.2-2.3-2.32.5
Na content in liver0.10.10.30.2-0.10.20.2-0.20.2-0.20.2-0.1-0.5-0.20.20.20.2-0.2-0.30.0-0.20.2-0.3-0.30.3
Rb content in liver0.30.41.80.30.8-0.5-0.40.4-0.40.40.40.4-0.7-1.3-0.3-0.3-0.30.2-1.30.7-0.40.5-0.6-0.60.9
Se content in liver0.10.10.1-0.3-0.30.30.3-0.30.3-0.3-0.3-0.3-0.00.2-0.4-0.4-0.40.30.20.4-0.30.3-0.3-0.30.3
Sr content in liver0.30.20.9-0.2-0.30.1-0.20.2-0.20.2-0.40.21.00.9-0.1-0.1-0.10.10.5-0.30.9-0.60.60.7-0.8
Zn content in liver0.80.93.8-1.0-1.10.60.7-0.70.7-0.7-1.1-0.71.81.9-0.5-0.5-0.50.61.9-0.10.2-0.30.30.4-0.7
Bone: minimum diameter0.10.31.30.20.5-0.2-0.10.1-0.10.10.30.2-0.7-1.1-0.2-0.2-0.20.2-1.10.6-0.40.6-0.6-0.60.9
Time in familiar zone, hab. session 13.73.56.2-2.1-2.32.02.0-2.02.0-2.0-2.2-2.02.32.5-1.8-1.8-1.81.82.51.3-1.31.2-1.2-1.10.8
Time in novel zone, hab. session 11.91.95.31.61.8-1.4-1.41.4-1.41.41.71.4-2.2-2.31.21.21.2-1.2-2.3-0.60.4-0.40.40.30.1
Total zone transitions, hab. session 11.01.42.5-1.0-1.01.31.3-1.31.3-1.3-0.9-1.30.10.4-1.1-1.1-1.11.10.41.4-1.51.5-1.5-1.61.6
Total locomotion distance, hab. session 13.34.77.5-1.9-1.82.22.2-2.22.2-2.2-1.8-2.20.80.9-2.1-2.1-2.12.10.92.5-2.72.7-2.7-2.72.7
Locomotion velocity, hab. session 13.04.35.9-1.9-1.92.12.1-2.12.1-2.1-1.9-2.11.01.1-2.1-2.1-2.12.11.12.3-2.42.4-2.4-2.42.4
Time in familiar zone, hab. session 23.23.47.2-2.2-2.11.81.8-1.81.8-1.8-2.2-1.82.72.6-1.9-1.9-1.91.92.61.3-1.11.0-0.9-0.90.5
Time in novel zone, hab. session 23.33.37.52.22.2-1.8-1.81.8-1.81.82.21.8-2.7-2.71.81.81.8-1.8-2.7-1.10.9-0.90.80.7-0.3
Total zone transitions, hab. session 20.30.41.50.40.40.00.0-0.00.0-0.00.5-0.0-1.2-1.20.10.10.1-0.1-1.20.5-0.70.7-0.8-0.81.1
Total locomotion distance, hab. session 20.71.01.8-0.8-0.81.11.1-1.11.1-1.1-0.7-1.10.10.3-0.8-0.8-0.80.80.31.1-1.41.3-1.3-1.31.3
Locomotion velocity, hab. session 21.01.42.7-0.9-1.01.21.2-1.21.2-1.2-0.8-1.2-0.00.3-0.9-0.9-0.90.90.31.3-1.61.6-1.6-1.61.6
Novel to familiar place preference ratio1.41.54.41.51.5-1.1-1.11.1-1.11.11.51.1-2.1-2.11.11.11.1-1.1-2.1-0.50.3-0.30.20.20.2
Novelty place preference0.90.93.01.11.2-0.8-0.80.8-0.80.81.20.8-1.7-1.70.80.80.8-0.8-1.7-0.20.1-0.10.0-0.00.3
Time in novel zone, NPP test1.31.33.91.41.4-1.1-1.11.1-1.11.11.41.1-1.9-2.01.01.01.0-1.0-2.0-0.50.4-0.30.30.20.1
Total zone transitions, NPP test0.20.21.40.60.4-0.1-0.10.1-0.10.10.60.1-1.2-0.80.50.50.5-0.5-0.8-0.1-0.20.1-0.2-0.20.3
Total locomotion distance, NPP test0.20.20.80.0-0.10.40.4-0.40.4-0.40.1-0.4-0.7-0.5-0.1-0.1-0.10.1-0.50.5-0.90.7-0.8-0.80.9
Locomotion velocity, NPP test0.30.41.1-0.3-0.40.70.7-0.70.7-0.7-0.3-0.7-0.4-0.1-0.4-0.4-0.40.4-0.10.7-1.10.9-0.9-1.01.0
Intraocular pressure0.20.31.5-0.3-0.70.40.3-0.30.3-0.3-0.4-0.20.81.20.20.20.2-0.21.2-0.70.6-0.60.60.6-1.0
Delta distance traveled before/after self-admin0.00.00.10.10.2-0.1-0.10.1-0.10.10.00.1-0.2-0.3-0.2-0.2-0.20.2-0.30.3-0.10.1-0.1-0.10.2
Delta ambulatory time before/after self-admin0.10.10.30.00.10.00.0-0.00.0-0.0-0.0-0.0-0.3-0.4-0.3-0.3-0.30.3-0.40.6-0.40.4-0.4-0.40.6
Parametrial fat weight0.00.00.1-0.2-0.20.10.1-0.10.1-0.1-0.2-0.10.40.3-0.1-0.1-0.10.10.4-0.00.2-0.10.10.1-0.2
Pavlov. Cond. lever latency0.40.51.60.40.4-0.7-0.70.7-0.70.70.30.70.20.10.50.50.5-0.50.1-0.81.3-1.01.11.1-1.1
Pavlov. Cond. magazine entry latency1.21.52.5-1.4-1.41.31.3-1.31.3-1.3-1.4-1.31.61.5-1.2-1.2-1.21.21.50.9-1.20.9-0.9-0.90.6
Pavlov. Cond. change in total contacts0.10.10.30.30.5-0.4-0.40.4-0.40.40.40.4-0.4-0.60.30.30.3-0.3-0.6-0.2-0.1-0.10.10.1-0.0
Pavlov. Cond. index score0.70.91.9-0.9-0.91.01.0-1.01.0-1.0-0.8-1.00.50.5-0.9-0.9-0.90.90.51.0-1.41.1-1.1-1.11.1
Pavlov. Cond. latency score1.01.22.7-1.0-0.91.11.1-1.11.1-1.1-0.9-1.10.40.4-1.0-1.0-1.01.00.41.3-1.61.4-1.4-1.41.4
Pavlov. Cond. lever contacts0.50.62.0-0.3-0.30.70.7-0.70.7-0.7-0.2-0.7-0.5-0.3-0.4-0.4-0.40.4-0.30.9-1.41.1-1.1-1.21.3
Pavlov. Cond. magazine entry number0.50.60.90.80.8-0.8-0.80.8-0.80.80.80.8-0.8-0.80.70.70.7-0.7-0.8-0.60.9-0.60.60.6-0.5
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.0-0.0-0.2-0.20.2-0.20.2-0.00.20.60.40.10.10.1-0.10.4-0.40.6-0.50.50.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.91.12.1-1.0-1.01.11.1-1.11.1-1.1-0.9-1.10.60.6-1.0-1.0-1.01.00.61.1-1.41.2-1.2-1.21.1
Pavlov. Cond. response bias0.60.81.2-1.0-1.01.01.0-1.01.0-1.0-0.9-1.00.90.9-0.8-0.8-0.80.80.90.7-1.10.8-0.8-0.80.6
Pavlov. Cond. lever latency1.41.92.41.51.6-1.5-1.51.5-1.51.51.61.5-1.3-1.51.51.51.5-1.5-1.5-1.31.1-1.21.21.1-1.0
Pavlov. Cond. magazine entry latency2.32.73.3-1.8-1.81.71.7-1.71.7-1.7-1.8-1.71.51.6-1.7-1.7-1.71.81.61.5-1.51.5-1.5-1.41.3
Pavlov. Cond. change in total contacts0.60.91.3-1.1-1.00.90.9-0.90.9-0.9-1.1-0.81.11.0-1.1-1.1-1.11.11.00.9-0.60.7-0.7-0.70.6
Pavlov. Cond. index score1.92.43.1-1.8-1.71.61.6-1.61.6-1.6-1.8-1.51.61.7-1.7-1.7-1.71.71.71.4-1.21.3-1.3-1.21.1
Pavlov. Cond. latency score2.12.73.3-1.8-1.81.71.7-1.71.7-1.7-1.8-1.71.51.7-1.7-1.7-1.71.71.71.5-1.41.4-1.4-1.41.2
Pavlov. Cond. lever contacts1.11.42.3-1.4-1.41.21.2-1.21.2-1.2-1.4-1.21.41.5-1.3-1.3-1.31.31.51.0-0.70.9-0.8-0.80.6
Pavlov. Cond. magazine entry number2.22.73.31.81.7-1.7-1.71.7-1.71.71.81.6-1.6-1.51.81.81.8-1.8-1.5-1.61.5-1.51.51.4-1.3
Pavlov. Cond. intertrial magazine entries1.21.61.91.31.2-1.3-1.31.3-1.31.31.21.3-0.9-0.91.31.31.3-1.3-0.9-1.41.4-1.41.41.4-1.3
Pavlov. Cond. lever-magazine prob. diff.2.12.73.4-1.8-1.71.61.6-1.61.6-1.6-1.8-1.61.71.6-1.8-1.8-1.81.81.61.6-1.31.4-1.4-1.41.2
Pavlov. Cond. response bias1.72.33.4-1.8-1.71.51.5-1.51.5-1.5-1.8-1.51.81.8-1.7-1.7-1.71.71.81.3-1.01.1-1.1-1.00.8
Time in closed arm before self-admin0.20.21.00.20.10.20.2-0.20.2-0.20.2-0.2-1.0-0.7-0.1-0.1-0.10.1-0.70.5-0.60.6-0.6-0.70.8
Time in closed arm after self-admin0.20.20.50.40.6-0.6-0.60.6-0.60.60.40.5-0.2-0.70.10.10.1-0.1-0.7-0.00.6-0.30.30.3-0.2
Time in open arm before self-admin0.30.32.0-0.7-0.30.10.1-0.10.1-0.1-0.7-0.11.40.6-0.9-0.9-0.90.90.50.40.00.1-0.1-0.10.1
Time in open arm after self-admin1.31.42.11.31.1-1.2-1.21.2-1.21.21.21.2-1.1-0.91.31.31.3-1.3-0.9-1.41.0-1.21.21.2-1.1
Bone: periosteal estimation0.40.94.50.91.3-0.7-0.70.7-0.70.71.00.7-1.5-2.10.30.30.3-0.3-2.10.3-0.10.3-0.4-0.50.8
Bone: periosteal perimeter0.40.72.3-0.4-0.10.50.5-0.50.5-0.5-0.3-0.4-0.3-0.8-0.9-0.9-0.90.9-0.71.3-1.11.2-1.3-1.31.5
Bone: post-yield work0.30.40.70.70.7-0.7-0.70.7-0.70.70.60.8-0.6-0.80.50.50.5-0.5-0.8-0.40.6-0.50.50.5-0.3
Progressive ratio test 1 active lever presses1.11.21.81.21.4-1.3-1.31.3-1.31.31.11.3-1.1-1.30.80.80.8-0.8-1.3-0.81.0-0.90.90.9-0.7
Progressive ratio test 1 breakpoint1.11.22.01.21.4-1.3-1.31.3-1.31.31.11.3-1.2-1.40.80.80.8-0.8-1.4-0.71.0-0.90.80.8-0.6
Progressive ratio test 1 inactive lever presses0.20.20.7-0.40.2-0.1-0.10.1-0.10.1-0.30.10.8-0.4-0.8-0.8-0.80.9-0.40.70.10.3-0.4-0.40.5
Progressive ratio test 2 active lever presses0.30.30.90.60.9-0.7-0.70.7-0.70.70.50.7-0.5-1.00.20.20.2-0.1-1.0-0.20.6-0.40.30.3-0.1
Progressive ratio test 2 breakpoint0.10.10.60.10.4-0.2-0.20.2-0.20.20.00.2-0.2-0.8-0.4-0.4-0.40.5-0.80.5-0.10.3-0.3-0.40.5
Progressive ratio test 2 inactive lever presses0.10.20.80.20.6-0.4-0.40.4-0.40.40.20.4-0.2-0.9-0.3-0.3-0.30.4-0.90.30.20.1-0.1-0.20.4
Incentive Sensitization - Responses0.20.20.5-0.5-0.20.30.3-0.30.3-0.3-0.5-0.30.60.2-0.6-0.6-0.60.70.20.5-0.30.4-0.4-0.40.4
Incentive Sensitization - Breakpoint0.30.30.8-0.6-0.40.40.4-0.40.4-0.4-0.6-0.40.70.2-0.8-0.8-0.80.90.20.8-0.50.6-0.6-0.60.6
Sum of active levers in priming session hrs 5-60.20.20.4-0.5-0.60.50.5-0.50.5-0.5-0.5-0.50.60.6-0.4-0.4-0.40.40.60.3-0.20.3-0.3-0.30.2
Progressive ratio1.21.42.01.21.4-1.4-1.41.4-1.41.41.21.4-0.9-1.21.11.11.1-1.1-1.2-1.01.2-1.11.11.1-0.9
Food seeking constrained by brief footshock1.31.63.1-1.3-1.71.61.5-1.51.5-1.5-1.3-1.51.11.8-0.9-0.9-0.90.91.70.7-1.10.9-0.9-0.90.6
Seeking ratio, punishment vs. effort2.02.43.9-1.6-2.01.91.8-1.81.8-1.8-1.7-1.81.42.0-1.2-1.2-1.21.21.91.0-1.41.2-1.2-1.20.9
Retroperitoneal fat weight2.58.29.63.13.1-3.1-3.03.0-3.03.03.03.1-2.7-2.82.92.92.9-2.9-2.8-2.72.7-2.62.62.5-2.2
Reaction time number correct1.52.23.21.41.3-1.5-1.51.5-1.51.51.51.4-0.9-0.81.61.61.6-1.8-0.7-1.71.6-1.71.71.7-1.7
Reaction time mean minus median1.31.72.1-1.4-1.41.41.4-1.41.4-1.4-1.4-1.41.21.3-1.4-1.4-1.41.41.31.3-1.21.2-1.2-1.21.0
Reaction time mean minus median AUC2.53.34.5-1.7-1.61.91.9-1.91.9-1.9-1.6-2.00.70.9-1.8-1.8-1.81.80.92.0-2.12.1-2.1-2.12.1
Reaction time num false alarms0.60.91.21.01.0-1.0-1.01.0-1.01.00.91.1-0.9-0.90.90.90.9-0.9-0.8-0.80.9-0.90.90.9-0.8
Reaction time num false alarms AUC0.91.31.71.11.1-1.2-1.31.3-1.31.31.11.3-0.8-0.81.01.01.0-1.1-0.8-1.11.2-1.21.21.2-1.1
Reaction time trials correct on left1.52.23.21.41.3-1.5-1.51.5-1.51.51.51.4-0.9-0.81.61.61.6-1.8-0.7-1.71.6-1.71.71.7-1.7
Reaction time trials on left1.42.02.91.41.2-1.4-1.41.4-1.41.41.41.4-0.9-0.81.61.61.6-1.7-0.7-1.71.5-1.61.61.6-1.6
Reaction time mean1.72.33.5-1.5-1.51.71.7-1.71.7-1.7-1.4-1.70.71.0-1.5-1.5-1.51.51.01.6-1.91.7-1.7-1.71.6
Reaction time mean AUC1.01.32.3-1.0-1.01.21.2-1.21.2-1.2-1.0-1.20.30.6-1.1-1.1-1.11.10.51.3-1.51.4-1.4-1.41.4
Median of all reaction times1.01.32.5-1.0-1.11.31.3-1.31.3-1.3-1.0-1.20.40.7-1.1-1.1-1.11.00.71.2-1.61.4-1.4-1.41.3
Reaction time omissions0.10.10.3-0.2-0.00.10.1-0.10.1-0.1-0.2-0.10.1-0.2-0.5-0.5-0.50.4-0.20.6-0.30.4-0.4-0.40.5
Reaction time false alarm rate0.10.10.30.40.4-0.3-0.30.3-0.30.30.30.4-0.5-0.50.20.20.2-0.1-0.5-0.10.1-0.20.20.2-0.1
Reaction time premature initiation rate0.70.93.2-1.1-1.30.90.9-0.90.9-0.9-1.2-0.91.71.8-0.7-0.7-0.70.81.80.3-0.10.2-0.1-0.1-0.2
Reaction time premature initiations0.30.51.9-0.3-0.60.10.1-0.10.1-0.1-0.4-0.11.31.40.20.20.2-0.11.4-0.70.8-0.80.80.8-1.1
Std. dev. reaction times1.21.62.0-1.3-1.21.31.3-1.31.3-1.3-1.3-1.40.70.9-1.4-1.4-1.41.40.91.4-1.41.4-1.4-1.41.3
Reaction time trials completed1.42.02.91.41.2-1.4-1.41.4-1.41.41.41.4-0.9-0.81.61.61.6-1.7-0.7-1.71.5-1.61.61.6-1.6
Reaction time trials AUC1.72.53.61.51.3-1.5-1.51.5-1.51.51.51.5-0.9-0.71.81.81.8-1.9-0.7-1.91.7-1.81.81.8-1.8
Run reversals in cocaine runway, females2.22.22.6-1.5-1.61.61.6-1.61.6-1.6-1.5-1.61.01.3-1.4-1.4-1.41.41.31.4-1.51.5-1.5-1.51.3
Run reversals in cocaine runway, males3.02.93.4-1.8-1.71.81.8-1.81.8-1.8-1.8-1.81.61.4-1.9-1.9-1.91.91.31.8-1.31.6-1.6-1.61.4
Latency to leave start box in cocaine runway0.40.41.40.00.00.30.3-0.30.3-0.30.0-0.4-1.0-0.8-0.4-0.4-0.40.4-0.80.8-0.90.9-0.9-1.01.2
Latency to leave start box in cocaine runway, F0.70.72.50.0-0.10.60.5-0.50.5-0.50.0-0.6-1.3-1.0-0.4-0.4-0.40.4-1.01.1-1.21.2-1.3-1.31.6
Latency to leave start box in cocaine runway, M0.30.30.60.30.4-0.6-0.60.6-0.60.60.30.60.20.00.30.30.3-0.30.1-0.50.7-0.70.70.8-0.8
Std. dev. time between licks in bursts1.31.53.0-1.1-0.81.01.0-1.01.0-1.0-1.1-1.00.80.3-1.5-1.5-1.51.50.31.7-1.31.5-1.5-1.61.7
Total sessions with >9 infusions0.50.61.7-0.10.40.00.0-0.00.0-0.0-0.1-0.0-0.3-1.3-0.9-0.9-0.91.0-1.31.2-0.40.9-0.9-1.01.3
Short access day 1 total inactive lever presses0.00.10.2-0.10.2-0.1-0.10.1-0.10.1-0.10.10.3-0.3-0.4-0.4-0.40.4-0.30.30.10.1-0.2-0.20.2
Short access day 10 total inactive lever presses0.20.20.80.00.3-0.5-0.50.5-0.50.50.00.50.90.10.00.00.0-0.00.1-0.30.8-0.60.60.6-0.6
Short access day 1 total infusions0.50.63.10.30.9-0.4-0.40.4-0.40.40.30.4-0.7-1.8-0.5-0.5-0.50.6-1.80.8-0.10.6-0.6-0.71.0
Short access day 10 total infusions0.40.51.40.71.0-0.9-0.90.9-0.90.90.60.9-0.7-1.20.20.20.2-0.2-1.2-0.10.6-0.30.30.3-0.1
Short access total infusions0.70.84.10.91.3-0.9-0.90.9-0.90.90.90.9-1.2-2.00.10.10.1-0.1-2.00.20.4-0.0-0.0-0.10.5
Short access day 1 locomotion0.50.51.2-0.6-0.20.40.4-0.40.4-0.4-0.6-0.40.2-0.2-1.0-1.0-1.01.0-0.21.1-0.60.8-0.9-0.91.0
Short access day 10 total locomotion1.21.45.3-1.5-1.10.80.8-0.80.8-0.8-1.4-0.82.31.4-1.5-1.5-1.51.51.41.0-0.50.6-0.6-0.60.5
Short access total locomotion0.40.41.0-0.7-0.30.40.4-0.40.4-0.4-0.7-0.40.70.2-1.0-1.0-1.01.00.20.9-0.50.7-0.7-0.70.8
One hour access (0.3 mA shock)0.30.40.60.70.7-0.6-0.60.6-0.60.60.70.6-0.6-0.80.60.60.6-0.6-0.8-0.50.7-0.50.50.5-0.4
Compulsive drug intake0.20.20.70.50.4-0.3-0.30.3-0.30.30.60.3-0.8-0.50.70.70.7-0.7-0.5-0.50.4-0.30.30.3-0.3
One hour access (shock baseline)0.20.20.40.20.5-0.6-0.60.6-0.60.60.20.60.4-0.20.10.10.1-0.0-0.2-0.20.6-0.50.50.5-0.5
Social response proportion1.11.11.8-1.0-1.31.31.3-1.31.3-1.3-1.0-1.30.61.0-0.8-0.8-0.80.71.00.9-1.11.0-1.0-1.00.9
Social responses9.512.214.5-3.6-3.83.83.8-3.83.8-3.8-3.6-3.82.93.3-3.5-3.5-3.53.43.33.3-3.23.3-3.2-3.22.9
Social time1.41.82.51.41.4-1.4-1.41.4-1.41.41.51.4-1.2-1.21.61.61.6-1.6-1.1-1.41.1-1.21.21.2-1.1
Soleus weight5.817.121.44.64.5-4.3-4.34.3-4.34.34.64.2-4.6-4.34.44.44.4-4.4-4.3-3.73.5-3.43.43.3-2.8
Bone: stiffness3.14.89.72.62.7-2.3-2.22.2-2.22.22.62.3-2.9-3.12.12.12.1-2.0-3.1-1.41.6-1.41.31.3-0.8
Tibialis anterior weight1.23.95.62.22.1-2.1-2.12.1-2.12.12.22.1-2.4-2.12.12.12.1-2.1-2.1-1.71.6-1.61.61.5-1.2
Time to tail flick, vehicle, before self-admin3.33.45.9-1.7-1.41.71.7-1.71.7-1.7-1.6-1.81.30.5-2.1-2.1-2.12.10.62.4-1.82.2-2.2-2.22.3
Time to tail flick, vehicle, after self-admin0.10.10.7-0.3-0.30.10.1-0.10.1-0.1-0.3-0.10.60.8-0.0-0.0-0.00.00.8-0.40.2-0.40.40.4-0.6
Time to tail flick, test, before self-admin2.02.03.0-1.3-1.11.41.4-1.41.4-1.4-1.3-1.30.50.6-1.6-1.6-1.61.60.51.7-1.71.7-1.7-1.71.7
Time to tail flick, test, after self-admin0.60.61.3-0.5-0.40.70.7-0.70.7-0.7-0.5-0.7-0.0-0.1-0.8-0.8-0.80.8-0.11.1-0.91.0-1.0-1.01.1
Delta time to tail flick, vehicle, before/after SA2.72.75.21.51.0-1.4-1.41.4-1.41.41.41.5-1.1-0.22.02.02.0-2.0-0.2-2.31.6-2.02.02.1-2.2
Delta time to tail flick, test, before/after SA0.10.10.40.0-0.2-0.0-0.00.0-0.00.00.00.00.40.50.40.40.4-0.40.6-0.50.4-0.50.50.5-0.7
Tibia length0.71.94.1-1.6-1.71.41.5-1.51.5-1.5-1.6-1.61.61.8-1.2-1.2-1.21.32.01.0-1.11.0-0.9-0.90.6
Ambulatory time before self-admin0.20.20.4-0.5-0.60.60.6-0.60.6-0.6-0.5-0.60.60.5-0.4-0.4-0.40.40.50.3-0.30.4-0.4-0.40.3
Ambulatory time after self-admin0.10.10.2-0.3-0.20.30.3-0.30.3-0.3-0.2-0.30.20.1-0.3-0.3-0.30.30.10.4-0.20.3-0.4-0.40.4
Bone: tissue strength3.02.95.42.02.1-1.8-1.81.8-1.81.82.01.9-2.1-2.31.61.61.6-1.6-2.3-1.21.3-1.21.11.1-0.7
Total heroin consumption2.42.83.5-1.8-1.91.91.9-1.91.9-1.9-1.7-1.91.51.7-1.6-1.6-1.61.61.71.5-1.71.6-1.5-1.51.3
Bone: trabecular number1.62.54.4-1.3-1.31.71.7-1.71.7-1.7-1.3-1.60.20.5-1.6-1.6-1.61.60.51.9-1.92.0-2.0-2.02.1
Bone: trabecular spacing1.82.35.90.90.9-1.5-1.51.5-1.51.50.91.40.50.31.41.41.4-1.40.3-2.02.0-2.12.22.2-2.4
Bone: trabecular thickness2.12.58.3-0.5-0.31.11.1-1.11.1-1.1-0.4-1.1-1.2-1.3-1.3-1.3-1.31.3-1.32.1-2.12.4-2.4-2.52.9
Bone: trabecular tissue density6.38.910.53.13.2-3.2-3.23.2-3.23.23.13.1-2.6-2.83.03.03.0-2.9-2.7-2.83.1-2.82.82.8-2.5
Water consumed over 24 hours0.30.41.70.70.8-0.5-0.50.5-0.50.50.70.5-1.1-1.30.40.40.4-0.4-1.30.0-0.10.2-0.2-0.20.5
Number of responses in last shaping day1.21.22.7-1.3-0.80.80.8-0.80.8-0.8-1.3-0.81.70.7-1.6-1.6-1.61.60.71.3-0.80.9-0.9-0.90.9