Hub : Genes

Desi1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA NM_001025703.1 0.1 0.05 9.9e-10 0.03 0.06 0.06 0.05 2.5e-04 2.1e-07 7.6e-07 1.8e-06
2 Liver alternative polyA XM_039079283.1 0.08 0.04 2.3e-08 0.04 0.05 0.05 0.05 5.2e-05 1.3e-06 5.7e-06 6.8e-06
3 Liver alternative polyA XM_039079283.1 0.1 0.06 3.8e-09 0.04 0.06 0.06 0.05 2.6e-05 4.6e-07 7.1e-07 1.1e-06
4 Liver alternative polyA NM_001025703.1 0.07 0.04 9.0e-08 0.04 0.05 0.05 0.05 9.1e-06 2.7e-06 5.0e-06 5.5e-06
5 Liver isoform ratio NM_001025703.1 0.05 0.03 7.2e-06 0.02 0.03 0.03 0.03 1.1e-03 5.8e-04 7.9e-04 5.6e-04
6 Liver isoform ratio XM_039079283.1 0.06 0.03 2.7e-06 0.03 0.04 0.04 0.03 4.2e-04 3.9e-05 9.0e-05 1.1e-04
7 NAcc mRNA stability Desi1 0.02 0.01 6.7e-03 0.02 0.02 0.01 0.02 1.2e-03 2.8e-03 3.4e-02 1.9e-03
8 Adipose isoform ratio NM_001025703.1 0.09 0.04 3.9e-11 0.07 0.07 0.05 0.06 3.1e-08 7.3e-08 1.2e-06 9.3e-07
9 Adipose mRNA stability Desi1 0.33 0.13 0.0e+00 0.25 0.25 0.24 0.25 1.4e-27 1.4e-27 7.6e-27 1.6e-27
10 BLA gene expression Desi1 0.13 0.08 1.6e-03 0.04 0.04 0.01 0.03 4.0e-03 4.9e-03 5.7e-02 8.9e-03
11 Brain gene expression Desi1 0.29 0.13 1.7e-14 0.17 0.15 0.14 0.16 2.7e-15 4.3e-14 2.3e-13 9.8e-15
12 Brain mRNA stability Desi1 0.04 0.03 5.5e-05 0.03 0.03 0.03 0.02 8.7e-04 4.6e-04 3.9e-04 3.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.20.40.50.6-0.6-0.50.60.5-0.6-0.60.7-0.7-0.5-0.6-0.7
Area under the delay curve0.40.40.70.8-0.8-0.80.60.6-0.6-0.50.2-0.3-0.7-0.7-0.7
BMI with tail1.44.76.9-2.42.42.6-2.5-2.42.52.1-2.32.40.30.52.0
BMI without tail0.10.20.7-0.70.70.8-0.5-0.20.5-0.2-0.10.2-0.2-0.0-0.0
Body weight1.77.19.6-2.92.93.0-2.9-3.12.83.0-2.72.71.91.91.9
Weight adjusted by age0.20.21.2-0.10.1-0.10.0-0.2-0.10.30.2-0.11.11.1-0.4
Bone surface0.20.30.40.4-0.5-0.60.50.7-0.6-0.50.6-0.50.50.6-0.2
Bone volume0.00.00.10.1-0.1-0.10.10.2-0.2-0.20.3-0.20.30.3-0.2
Breakpoint value in progressive ratio session0.20.20.90.2-0.2-0.00.10.3-0.1-0.40.2-0.2-1.0-0.8-0.1
Number of licking bursts0.60.81.21.0-1.0-1.10.91.1-1.0-0.90.8-0.7-0.5-0.4-0.6
Context. condit. distance diff. score7.28.710.8-3.33.33.1-3.1-2.93.12.9-2.93.12.62.52.4
Locomotion velocity, session 10.30.41.90.2-0.2-0.40.20.4-0.3-0.00.1-0.01.41.40.2
Locomotion distance, session 12.63.45.72.1-2.1-2.42.12.2-2.2-1.81.8-1.8-0.3-0.3-1.2
Locomotion velocity, session 20.20.30.7-0.60.60.6-0.5-0.40.50.4-0.40.50.50.80.3
Locomotion distance, session 23.14.46.12.5-2.5-2.42.22.2-2.2-2.01.9-2.0-2.0-2.0-0.9
Locomotion velocity, session 30.40.42.0-0.50.50.3-0.4-0.30.30.5-0.30.41.21.40.1
Locomotion distance, session 31.21.32.61.3-1.3-1.61.41.4-1.4-1.01.0-1.10.10.4-0.8
Stereotopy head waving bouts, day 30.91.11.4-1.11.11.1-1.1-1.21.11.1-1.01.01.00.90.7
Stereotopy head waving duration, day 33.94.76.4-2.52.52.5-2.3-2.32.32.0-1.92.02.12.01.2
Locomotion velocity, session 70.10.20.4-0.40.40.2-0.3-0.50.30.6-0.40.40.40.6-0.1
Locomotion distance, session 70.30.31.30.6-0.6-0.60.40.1-0.40.1-0.0-0.1-1.2-1.1-0.3
Stereotopy head waving bouts, day 74.14.610.4-2.22.22.0-1.9-1.71.81.7-1.71.73.23.21.5
Stereotopy head waving duration, day 73.13.88.1-2.22.12.0-1.8-1.71.71.5-1.41.42.82.81.0
Locomotion velocity, session 82.12.54.9-1.61.61.6-1.7-1.31.61.4-1.51.71.31.42.2
Locomotion distance, session 80.91.31.7-1.31.31.2-1.2-0.91.20.9-1.01.21.11.11.1
Degree of sensitization distance2.52.53.9-1.71.61.9-1.8-2.01.91.6-1.61.7-0.6-0.71.0
Degree of sensitization stereotypy2.83.18.5-1.71.71.5-1.4-1.31.31.3-1.41.32.92.91.1
Conditioned locomotion0.80.91.9-1.11.11.0-0.9-0.80.90.8-0.80.91.41.00.3
Cocaine response after cond. corrected0.10.10.1-0.30.30.2-0.2-0.30.20.3-0.00.10.30.3-0.4
Cocaine response after cond. not corrected0.10.10.2-0.30.30.3-0.2-0.10.20.00.20.00.20.1-0.5
Cocaine response before conditioning0.10.10.50.1-0.1-0.10.20.5-0.2-0.70.5-0.3-0.4-0.4-0.5
Saline control response0.20.30.9-0.60.60.4-0.30.40.3-0.40.20.21.00.9-0.4
Bone: connectivity density0.10.10.20.4-0.4-0.40.40.2-0.4-0.20.4-0.5-0.3-0.4-0.4
Bone: cortical apparent density0.71.01.61.2-1.2-1.31.11.1-1.1-0.90.8-0.9-0.5-0.6-0.8
Bone: cortical area1.62.42.9-1.71.71.7-1.7-1.51.61.5-1.71.61.31.31.2
Bone: cortical porosity0.70.71.4-1.11.11.2-1.0-1.01.00.7-0.50.70.60.6-0.4
Bone: cortical porosity1.51.62.8-1.61.61.7-1.4-1.51.41.2-1.01.11.01.00.2
Bone: cortical thickness0.20.30.7-0.20.20.4-0.5-0.50.50.5-0.80.6-0.8-0.70.5
Bone: cortical thickness0.30.30.8-0.20.20.3-0.5-0.40.50.5-0.90.7-0.8-0.70.8
Bone: cortical tissue density0.70.91.51.2-1.2-1.21.11.1-1.1-0.90.7-0.9-0.5-0.6-0.7
Condit. Reinf. active minus inactive responses0.30.30.80.7-0.7-0.60.50.5-0.5-0.40.3-0.4-0.9-0.9-0.3
Condit. Reinf. active-inactive response ratio0.20.20.3-0.40.40.4-0.5-0.40.50.5-0.50.50.40.40.6
Condit. Reinf. active responses1.72.13.61.4-1.4-1.31.31.5-1.3-1.51.2-1.3-1.9-1.7-1.3
Condit. Reinf. inactive responses3.03.64.71.8-1.8-1.71.82.0-1.7-2.21.7-1.8-2.1-2.0-1.9
Incentive salience index mean0.81.02.31.1-1.1-1.00.80.8-0.8-0.80.6-0.7-1.5-1.4-0.8
Condit. Reinf. lever presses1.01.42.51.1-1.1-1.01.01.1-1.0-1.10.9-1.0-1.6-1.4-1.4
Condit. Reinf. active minus inactive responses0.20.21.20.5-0.5-0.50.20.3-0.20.0-0.30.1-0.4-0.61.1
Condit. Reinf. active-inactive response ratio0.20.31.70.3-0.3-0.2-0.1-0.20.00.4-0.50.2-0.5-0.71.3
Condit. Reinf. active responses0.30.52.1-0.30.30.3-0.6-0.30.50.6-0.90.80.60.51.4
Condit. Reinf. inactive responses0.70.81.4-0.90.90.7-0.9-0.60.90.8-1.01.11.01.20.6
Condit. Reinf. lever presses0.40.50.70.8-0.8-0.80.70.7-0.7-0.70.7-0.6-0.8-0.80.7
Condit. Reinf. lever reinforcers received0.20.21.7-0.10.10.1-0.3-0.10.20.3-0.60.50.30.21.3
Conditioned reinforcement - actives0.30.30.9-0.30.30.1-0.4-0.10.30.4-0.90.70.80.90.1
Conditioned reinforcement - inactives0.30.30.70.5-0.5-0.40.20.8-0.3-0.7-0.1-0.1-0.8-0.8-0.6
Conditioned locomotion1.61.93.6-1.31.31.3-1.5-1.31.41.3-1.91.70.70.91.3
Patch foraging indifference point 0 sec0.40.71.10.8-0.8-0.60.70.9-0.7-1.10.9-0.8-1.0-1.0-0.3
Patch foraging indifference point AUC0.30.41.10.9-0.9-1.00.70.6-0.8-0.20.4-0.3-0.2-0.10.5
Delay disc. indifference point, 0s delay0.91.02.1-1.31.31.4-1.3-1.01.30.6-0.71.10.00.2-0.1
Delay disc. indifference point, 16s delay1.92.03.11.7-1.7-1.81.61.3-1.6-1.31.1-1.3-1.1-1.1-0.8
Delay disc. indifference point, 2s delay0.10.10.4-0.10.10.1-0.2-0.10.20.1-0.40.4-0.4-0.2-0.6
Delay disc. indifference point, 24s delay0.40.41.10.8-0.7-1.00.70.2-0.80.10.0-0.30.80.8-0.2
Delay disc. indifference point, 4s delay0.20.20.90.4-0.4-0.30.10.4-0.1-0.4-0.10.1-1.0-0.9-0.1
Delay disc. indifference point, 8s delay1.11.11.81.3-1.2-1.31.11.0-1.1-0.80.5-0.8-1.1-1.0-0.9
Indifference point function ln k1.21.72.7-1.61.61.7-1.4-1.41.51.2-1.11.21.01.01.0
Indifference point function log k1.21.72.7-1.61.61.7-1.4-1.41.51.2-1.11.21.01.01.0
Patch foraging total patch changes 0 sec0.50.81.30.9-0.9-0.70.81.0-0.8-1.20.9-1.0-1.1-1.1-0.4
Patch foraging total patch changes 12 sec0.00.10.10.3-0.3-0.30.10.2-0.1-0.20.2-0.1-0.4-0.30.3
Patch foraging total patch changes 18 sec0.20.30.50.6-0.6-0.50.40.5-0.4-0.50.2-0.3-0.7-0.70.6
Patch foraging total patch changes 24 sec0.30.40.60.7-0.7-0.80.70.8-0.7-0.70.6-0.6-0.4-0.4-0.1
Patch foraging total patch changes 6 sec0.40.61.20.9-0.9-0.80.71.0-0.7-0.90.8-0.6-1.1-0.8-0.1
Patch foraging time to switch 0 sec0.20.22.2-0.30.30.4-0.1-0.40.2-0.00.1-0.20.30.1-1.5
Patch foraging water rate 0 sec0.30.41.10.5-0.6-0.40.40.6-0.4-0.50.6-0.4-1.1-0.81.0
Patch foraging water rate 12 sec0.30.41.20.6-0.6-0.50.61.0-0.6-1.10.7-0.7-0.2-0.00.5
Patch foraging water rate 18 sec1.31.82.71.5-1.5-1.51.51.4-1.5-1.41.6-1.5-0.8-0.7-0.1
Patch foraging water rate 24 sec0.10.21.8-0.10.10.3-0.2-0.10.20.0-0.10.1-0.3-0.21.4
Patch foraging water rate 6 sec0.81.22.31.1-1.1-1.21.21.5-1.2-1.41.2-1.2-0.10.0-0.8
Seeking ratio, delayed vs. immediate footshock3.54.15.02.2-2.2-2.12.11.8-2.1-1.81.9-2.1-2.2-2.2-0.9
Distance traveled before self-admin0.50.53.00.3-0.3-0.10.00.20.1-0.3-0.30.1-1.7-1.7-0.3
Distance traveled after self-admin0.10.10.30.1-0.10.1-0.20.20.1-0.2-0.30.2-0.4-0.50.2
Extensor digitorum longus weight0.10.61.50.5-0.5-0.40.60.9-0.6-1.11.1-0.8-0.4-0.5-1.2
Bone: elastic displacement0.20.31.5-0.40.40.3-0.20.10.10.00.10.11.11.20.0
Bone: elastic work2.33.04.3-2.02.02.1-1.9-1.81.91.6-1.51.61.31.41.5
Bone: endosteal estimation1.32.86.9-1.91.91.7-1.5-1.11.41.1-1.01.22.62.61.2
Bone: endosteal perimeter2.75.611.6-2.62.62.4-2.2-2.02.11.8-1.81.93.43.31.1
Epididymis fat weight4.09.211.0-3.23.33.0-3.0-3.33.03.3-3.03.02.92.92.1
Delta time in closed arm before/after self-admin1.11.01.9-0.90.90.9-1.1-1.11.11.2-1.41.40.10.11.0
Delta time in open arm before/after self-admin0.30.30.80.2-0.2-0.20.40.9-0.4-0.90.4-0.50.60.5-0.7
Diff in mean of infusions in LGA sessions0.60.61.11.0-1.0-1.00.80.2-0.80.00.6-0.7-1.1-1.0-0.8
Delay discount exponential model param0.40.50.9-0.90.80.9-0.7-0.70.70.6-0.30.40.70.60.7
Extinction: sum of active levers before priming0.10.10.30.1-0.1-0.10.10.1-0.1-0.10.00.0-0.6-0.4-0.4
Active lever presses in extinction session 60.10.10.2-0.40.30.4-0.4-0.30.40.3-0.10.3-0.5-0.5-0.2
Bone: final force1.32.13.9-1.21.21.4-1.5-1.81.51.9-1.71.50.10.22.0
Bone: final moment1.52.44.6-1.41.31.5-1.6-1.91.61.9-1.81.60.30.32.1
Food consumed during 24 hour testing period1.31.62.4-1.31.31.4-1.4-1.61.41.6-1.41.40.30.30.8
Glucose0.40.51.00.5-0.5-0.40.60.6-0.5-0.90.9-0.8-1.0-1.0-1.0
Heart weight2.53.56.1-2.22.22.5-2.3-1.72.31.3-2.12.00.40.41.6
Delay discount hyperbolic model param0.30.30.5-0.60.60.7-0.5-0.60.50.5-0.10.20.60.60.6
Intermittent access intake day 1-15 change0.50.50.60.8-0.8-0.80.70.8-0.7-0.70.6-0.6-0.7-0.8-0.4
Intermittent access intake escalation0.50.50.70.8-0.8-0.80.70.7-0.7-0.70.6-0.7-0.8-0.9-0.6
Intermittent access intake escalation 20.20.20.40.3-0.3-0.30.40.5-0.4-0.50.5-0.4-0.2-0.3-0.6
Intermitt. access day 1 inactive lever presses0.30.40.8-0.40.40.7-0.6-0.40.70.3-0.70.6-0.7-0.70.9
Intermitt. access day 15 inactive lever presses0.70.83.5-0.20.20.4-0.6-0.00.70.2-1.10.9-1.1-1.21.9
Intermitt. access escalation Index0.10.10.40.2-0.3-0.10.10.1-0.1-0.1-0.1-0.1-0.6-0.60.3
Intermittent access day 1 total infusions0.80.92.0-0.90.90.9-1.1-0.91.00.9-1.41.20.50.60.7
Intermittent access day 15 total infusions0.10.10.20.3-0.3-0.20.10.2-0.1-0.2-0.30.1-0.5-0.50.0
Intermittent access terminal intake (last 3 days)0.00.00.2-0.10.10.1-0.2-0.10.20.2-0.40.30.20.2-0.1
Intermittent access total infusions0.20.20.7-0.40.40.4-0.5-0.60.50.6-0.90.60.10.10.1
Intermittent access day 1 locomotion0.30.31.0-0.60.60.7-0.7-0.50.70.3-1.00.7-0.10.1-0.0
Intermittent access day 15 total locomotion0.10.10.4-0.30.30.3-0.3-0.50.30.4-0.60.40.30.3-0.2
Intermittent access total locomotion0.40.41.0-0.60.60.6-0.7-0.90.70.8-1.00.8-0.10.00.2
Intermittent access standard deviation0.60.61.1-0.80.81.0-0.9-0.81.00.6-1.10.9-0.1-0.20.7
Left kidney weight12.735.740.5-6.26.26.1-6.4-6.16.36.3-6.16.44.54.56.2
Right kidney weight13.237.044.0-6.36.36.3-6.6-6.26.56.4-6.46.64.24.36.2
Cocaine induced anxiety1.01.13.4-0.90.91.1-1.1-1.91.11.6-0.80.9-0.5-0.50.8
Post-drug Anxiety0.30.30.9-0.40.40.6-0.5-1.00.50.8-0.30.3-0.1-0.10.6
Baseline Anxiety1.31.43.11.1-1.1-1.31.31.7-1.3-1.61.2-1.2-0.1-0.1-0.9
Tail length0.10.41.20.4-0.4-0.40.60.6-0.6-0.70.8-0.80.20.2-1.1
Length with tail0.41.53.2-1.11.11.0-1.0-1.41.01.5-1.00.91.81.60.5
Length without tail1.12.45.0-1.31.31.2-1.5-1.91.42.2-1.71.61.41.31.6
Times rat made contact with spout0.30.40.9-0.50.50.5-0.7-0.60.70.8-0.90.9-0.2-0.10.3
Lifetime Intake0.70.81.9-0.70.70.8-0.9-1.00.91.0-1.41.1-0.2-0.10.8
Liver weight, left1.22.04.9-1.51.51.4-1.2-1.21.21.2-1.11.12.22.00.0
Liver weight, right3.05.07.6-2.52.52.3-2.2-2.22.22.2-1.92.12.72.80.5
Locomotor activity2.13.44.3-2.12.12.0-1.9-1.81.91.7-1.71.81.91.91.3
Locomotor testing distance0.00.00.10.1-0.1-0.10.10.2-0.1-0.10.1-0.10.10.1-0.4
Locomotor testing rearing1.52.33.1-1.81.81.7-1.7-1.51.61.4-1.71.61.31.30.3
Locomotion in novel chamber1.11.45.00.2-0.2-0.40.62.2-0.7-2.10.4-0.71.41.3-1.2
Locomotion in novel chamber post-restriction0.91.02.01.0-1.0-1.11.11.0-1.1-1.00.9-1.1-0.6-0.5-1.4
Fecal boli incidents, locomotor time 10.50.50.70.8-0.8-0.70.70.5-0.7-0.40.7-0.7-0.9-0.9-0.6
Change in fecal boli incidents, locomotor task1.11.14.1-0.40.40.2-0.4-0.40.30.8-0.90.72.02.01.4
Time >=10cm from walls, locomotor time 10.10.10.5-0.20.20.2-0.2-0.50.20.7-0.20.20.20.20.3
Bouts of movement, locomotor time 10.30.31.6-0.30.30.2-0.3-1.20.41.3-0.60.40.00.00.3
Total resting periods, locomotor time 10.20.21.00.1-0.0-0.1-0.1-0.90.11.0-0.30.2-0.6-0.60.1
Rest time, locomotor task time 10.40.41.1-0.30.30.4-0.5-0.70.50.7-0.80.6-1.1-1.10.5
Distance moved, locomotor task time 10.80.81.6-1.11.11.0-0.9-0.80.90.6-0.70.81.31.3-0.2
Vertical activity count, locomotor time 10.00.00.2-0.20.20.2-0.1-0.20.1-0.10.10.00.40.4-0.2
Time >=10cm from walls, locomotor time 20.10.10.20.3-0.3-0.20.30.3-0.4-0.30.5-0.4-0.0-0.0-0.5
Bouts of movement, locomotor time 20.30.30.7-0.40.40.5-0.5-0.50.60.5-0.80.6-0.7-0.7-0.1
Total resting periods, locomotor time 20.20.30.7-0.20.20.3-0.4-0.40.40.4-0.80.5-0.8-0.80.1
Rest time, locomotor task time 20.20.30.50.7-0.7-0.70.50.5-0.5-0.30.3-0.3-0.6-0.6-0.2
Distance moved, locomotor task time 21.01.21.9-1.41.41.3-1.2-0.91.20.7-1.01.11.01.0-0.2
Vertical activity count, locomotor time 20.50.60.8-0.90.90.9-0.8-0.60.80.6-0.50.70.80.80.3
Light reinforcement 10.30.51.9-0.50.50.4-0.30.40.2-0.3-0.20.31.41.40.8
Light reinforcement 20.91.21.6-1.21.31.2-1.1-1.21.21.1-0.91.01.00.91.1
Bone: marrow area1.43.07.2-1.91.91.8-1.5-1.21.51.1-1.01.32.72.71.3
Bone: maximum diameter4.58.310.0-3.23.23.2-3.1-2.83.02.7-2.92.82.82.72.2
Bone: maximum force2.44.25.7-2.02.02.1-2.3-2.32.22.3-2.32.20.70.82.4
Bone: maximum moment2.84.86.6-2.22.22.3-2.4-2.42.32.4-2.42.30.91.02.6
Mean time between licks in bursts0.50.71.60.8-0.8-0.70.80.8-0.8-0.90.8-0.9-0.6-0.8-1.3
Mean num. licks in bursts1.82.22.8-1.61.61.6-1.6-1.71.61.7-1.71.60.80.81.0
Cd content in liver0.90.91.5-1.21.21.1-1.1-0.81.10.8-0.91.10.90.80.4
Co content in liver0.40.41.8-0.60.60.7-0.7-0.50.70.5-0.50.7-0.1-0.31.3
Cu content in liver3.94.85.62.3-2.3-2.22.32.3-2.3-2.42.3-2.4-1.5-1.6-2.3
Fe content in liver0.20.20.4-0.60.60.6-0.4-0.10.4-0.10.20.10.60.6-0.3
K content in liver0.80.81.41.0-1.0-0.90.80.9-0.8-0.90.9-0.8-1.1-1.2-0.4
Mg content in liver1.51.53.11.3-1.3-1.11.11.1-1.1-1.21.0-1.1-1.5-1.7-1.1
Mn content in liver0.10.10.4-0.30.40.2-0.3-0.10.20.3-0.40.40.60.60.2
Na content in liver2.83.03.61.8-1.8-1.71.81.8-1.8-1.91.9-1.9-1.3-1.4-1.5
Rb content in liver0.00.00.20.2-0.2-0.20.10.1-0.10.00.0-0.0-0.1-0.5-0.1
Se content in liver0.70.81.20.9-0.9-1.01.01.0-1.0-1.01.1-1.0-0.2-0.2-1.0
Sr content in liver1.00.91.11.0-1.0-1.01.01.0-1.0-1.00.9-0.9-0.8-0.7-1.0
Zn content in liver1.11.21.81.1-1.1-1.11.21.2-1.2-1.21.3-1.3-0.2-0.3-1.1
Bone: minimum diameter0.91.63.2-1.51.41.4-1.2-1.01.20.9-1.11.11.71.80.8
Time in familiar zone, hab. session 10.10.10.40.1-0.1-0.20.00.0-0.10.3-0.40.20.50.60.2
Time in novel zone, hab. session 10.90.92.1-1.31.31.4-1.1-0.91.10.5-0.40.70.70.70.8
Total zone transitions, hab. session 13.75.18.12.6-2.6-2.82.62.8-2.7-2.32.3-2.2-0.6-0.7-1.5
Total locomotion distance, hab. session 11.62.34.21.4-1.4-1.71.72.1-1.8-1.71.7-1.50.60.6-1.2
Locomotion velocity, hab. session 12.02.95.11.7-1.7-2.01.92.3-2.0-2.01.8-1.70.00.1-1.4
Time in familiar zone, hab. session 20.30.31.2-0.40.40.2-0.1-0.00.10.0-0.10.01.01.1-1.0
Time in novel zone, hab. session 20.20.21.80.0-0.10.1-0.20.00.20.00.00.2-0.5-0.61.3
Total zone transitions, hab. session 21.11.52.61.5-1.5-1.51.31.6-1.4-1.31.0-1.0-0.6-0.8-0.3
Total locomotion distance, hab. session 20.81.11.91.1-1.1-1.11.11.4-1.1-1.31.0-1.0-0.7-0.7-0.4
Locomotion velocity, hab. session 21.52.03.21.5-1.5-1.51.51.8-1.5-1.71.4-1.4-1.0-0.9-0.8
Novel to familiar place preference ratio3.33.45.6-1.91.91.8-1.8-1.71.71.7-1.41.62.41.92.1
Novelty place preference4.44.56.9-2.22.22.1-2.0-2.02.02.0-1.71.92.62.22.3
Time in novel zone, NPP test5.45.68.0-2.52.52.3-2.3-2.22.22.2-2.02.22.82.42.6
Total zone transitions, NPP test3.14.47.22.4-2.4-2.62.42.7-2.5-2.22.0-2.0-0.6-0.6-1.3
Total locomotion distance, NPP test1.52.03.21.6-1.6-1.71.61.8-1.6-1.61.4-1.4-0.7-0.5-0.6
Locomotion velocity, NPP test2.33.24.72.0-2.0-2.12.02.2-2.0-1.91.8-1.8-0.9-0.8-1.4
Intraocular pressure0.40.51.1-0.50.60.4-0.5-0.50.50.7-0.90.71.01.00.9
Delta distance traveled before/after self-admin0.70.83.5-0.60.60.5-0.6-0.30.40.4-0.50.51.91.80.6
Delta ambulatory time before/after self-admin0.80.83.8-0.60.60.5-0.6-0.20.40.4-0.50.62.01.90.6
Parametrial fat weight0.10.20.3-0.40.40.4-0.5-0.50.50.5-0.40.5-0.4-0.30.6
Pavlov. Cond. lever latency1.41.72.9-1.31.31.2-1.2-1.21.21.2-1.21.21.71.51.4
Pavlov. Cond. magazine entry latency1.41.84.51.4-1.4-1.31.20.9-1.2-0.90.9-1.0-2.1-2.0-1.1
Pavlov. Cond. change in total contacts2.02.15.21.6-1.6-1.41.31.3-1.3-1.21.0-1.1-2.3-2.1-0.7
Pavlov. Cond. index score0.91.24.41.1-1.0-0.90.80.6-0.7-0.50.5-0.6-2.1-1.9-0.8
Pavlov. Cond. latency score0.81.03.80.9-0.9-0.80.70.6-0.7-0.60.5-0.6-2.0-1.8-0.8
Pavlov. Cond. lever contacts1.82.24.71.5-1.5-1.31.31.3-1.3-1.31.1-1.2-2.2-2.0-1.4
Pavlov. Cond. magazine entry number1.11.44.0-1.21.21.2-1.0-0.71.00.5-0.70.82.01.81.0
Pavlov. Cond. intertrial magazine entries1.01.21.61.3-1.3-1.21.21.2-1.2-1.21.1-1.1-0.8-0.9-0.2
Pavlov. Cond. lever-magazine prob. diff.1.11.44.11.2-1.2-1.11.00.7-0.9-0.70.7-0.8-2.0-1.9-1.0
Pavlov. Cond. response bias1.51.85.11.4-1.4-1.21.10.9-1.1-0.80.8-0.9-2.3-2.1-1.2
Pavlov. Cond. lever latency0.91.22.1-1.11.10.9-1.1-1.11.01.3-1.51.31.11.10.1
Pavlov. Cond. magazine entry latency4.14.76.52.5-2.6-2.32.21.8-2.1-1.92.1-2.2-2.5-2.5-0.1
Pavlov. Cond. change in total contacts0.81.23.01.1-1.1-0.70.70.5-0.7-0.70.9-0.9-1.6-1.71.4
Pavlov. Cond. index score2.63.34.42.1-2.1-1.81.81.5-1.8-1.72.0-1.9-2.1-2.10.1
Pavlov. Cond. latency score3.34.15.92.3-2.3-2.02.01.7-1.9-1.82.1-2.0-2.4-2.40.0
Pavlov. Cond. lever contacts0.91.22.01.1-1.1-0.91.01.0-1.0-1.21.4-1.2-1.2-1.20.2
Pavlov. Cond. magazine entry number2.12.63.9-1.92.01.7-1.6-1.21.61.2-1.51.61.91.9-0.5
Pavlov. Cond. intertrial magazine entries2.12.84.5-1.81.81.8-2.0-1.72.01.8-2.12.10.30.40.9
Pavlov. Cond. lever-magazine prob. diff.2.53.24.32.0-2.1-1.81.81.5-1.8-1.72.0-1.9-2.0-2.00.0
Pavlov. Cond. response bias1.11.42.11.3-1.4-1.11.11.0-1.1-1.21.3-1.3-1.4-1.40.5
Time in closed arm before self-admin5.25.98.32.2-2.3-2.02.42.1-2.3-2.62.9-2.8-2.3-2.4-2.7
Time in closed arm after self-admin0.40.40.8-0.80.80.9-0.8-0.70.80.5-0.50.7-0.1-0.3-0.4
Time in open arm before self-admin0.20.20.7-0.20.2-0.0-0.1-0.50.10.7-0.20.20.80.8-0.0
Time in open arm after self-admin0.30.30.90.2-0.2-0.30.50.5-0.5-0.50.4-0.60.81.0-0.8
Bone: periosteal estimation2.04.16.5-2.32.32.2-2.0-1.71.91.6-1.71.72.52.51.5
Bone: periosteal perimeter4.67.610.2-3.13.13.0-2.8-2.62.72.5-2.62.53.23.21.6
Bone: post-yield work0.10.20.4-0.30.30.4-0.5-0.30.50.4-0.60.6-0.5-0.30.6
Progressive ratio test 1 active lever presses0.40.40.9-0.30.30.3-0.6-0.90.60.9-1.00.8-0.5-0.30.7
Progressive ratio test 1 breakpoint0.30.30.7-0.20.20.2-0.4-0.80.40.9-0.80.6-0.4-0.20.4
Progressive ratio test 1 inactive lever presses0.70.72.5-0.40.40.7-0.7-0.60.80.4-1.00.7-1.6-1.40.7
Progressive ratio test 2 active lever presses0.30.31.00.7-0.6-0.70.30.1-0.30.1-0.20.1-1.0-0.90.3
Progressive ratio test 2 breakpoint0.30.31.30.4-0.4-0.40.1-0.2-0.10.4-0.40.2-1.1-1.00.4
Progressive ratio test 2 inactive lever presses0.91.03.51.0-1.0-0.80.60.9-0.6-0.80.1-0.3-1.9-1.9-0.0
Incentive Sensitization - Responses0.60.61.60.9-0.9-0.80.60.6-0.6-0.40.3-0.4-1.3-1.20.0
Incentive Sensitization - Breakpoint0.40.41.60.7-0.7-0.70.40.4-0.4-0.20.1-0.2-1.2-1.20.2
Sum of active levers in priming session hrs 5-60.10.10.30.1-0.10.00.1-0.1-0.1-0.10.2-0.2-0.5-0.4-0.5
Progressive ratio0.20.20.70.3-0.3-0.20.30.2-0.2-0.40.5-0.3-0.8-0.8-0.4
Food seeking constrained by brief footshock1.51.93.2-1.41.41.4-1.5-1.31.41.3-1.81.61.21.20.6
Seeking ratio, punishment vs. effort0.70.81.7-0.90.90.8-1.0-0.80.91.0-1.31.10.90.80.7
Retroperitoneal fat weight4.113.621.1-3.83.83.8-3.8-4.63.84.6-3.83.82.62.62.5
Reaction time number correct0.91.42.31.2-1.2-1.41.41.1-1.4-0.91.2-1.30.20.3-1.5
Reaction time mean minus median0.20.30.6-0.80.80.8-0.6-0.10.6-0.0-0.40.40.60.7-0.3
Reaction time mean minus median AUC0.81.01.7-1.31.31.3-1.1-0.91.20.7-1.01.00.80.8-0.1
Reaction time num false alarms0.20.21.1-0.40.40.3-0.10.40.1-0.50.3-0.10.81.0-0.4
Reaction time num false alarms AUC0.20.31.0-0.20.20.10.10.6-0.1-0.60.5-0.20.91.0-0.3
Reaction time trials correct on left0.91.42.31.2-1.2-1.41.41.1-1.4-0.91.2-1.30.20.3-1.5
Reaction time trials on left1.01.52.51.2-1.2-1.51.41.2-1.5-0.91.3-1.30.20.3-1.6
Reaction time mean0.10.10.40.1-0.1-0.00.20.2-0.1-0.40.2-0.4-0.2-0.2-0.6
Reaction time mean AUC0.10.10.50.2-0.2-0.10.20.2-0.2-0.40.2-0.3-0.2-0.2-0.7
Median of all reaction times0.20.30.40.5-0.5-0.40.50.3-0.5-0.50.5-0.7-0.5-0.6-0.7
Reaction time omissions0.20.30.60.5-0.5-0.60.60.8-0.6-0.70.6-0.50.10.1-0.3
Reaction time false alarm rate0.20.30.6-0.80.80.8-0.6-0.10.6-0.1-0.20.50.40.50.4
Reaction time premature initiation rate0.30.41.20.6-0.6-0.40.40.2-0.4-0.30.6-0.6-1.1-1.1-0.0
Reaction time premature initiations0.40.60.90.9-0.9-0.80.80.4-0.9-0.40.9-0.9-0.8-0.8-0.5
Std. dev. reaction times0.50.71.1-1.01.01.1-0.9-0.40.90.2-0.80.70.90.90.2
Reaction time trials completed1.01.52.51.2-1.2-1.51.41.2-1.5-0.91.3-1.30.20.3-1.6
Reaction time trials AUC0.81.12.11.0-1.0-1.31.20.9-1.3-0.71.1-1.20.30.4-1.4
Run reversals in cocaine runway, females0.80.71.90.6-0.6-0.80.91.0-0.9-0.90.8-0.80.70.6-1.4
Run reversals in cocaine runway, males0.80.82.9-0.50.60.3-0.5-0.30.50.7-0.80.81.71.71.0
Latency to leave start box in cocaine runway0.30.40.8-0.60.60.6-0.6-0.90.60.8-0.40.50.0-0.00.7
Latency to leave start box in cocaine runway, F0.20.20.50.4-0.4-0.40.50.3-0.5-0.40.7-0.6-0.4-0.50.3
Latency to leave start box in cocaine runway, M2.32.23.9-1.51.51.6-1.6-2.01.71.9-1.71.60.40.30.8
Std. dev. time between licks in bursts1.51.82.31.4-1.4-1.31.31.4-1.3-1.51.3-1.3-1.1-1.2-1.3
Total sessions with >9 infusions1.51.63.2-1.11.11.2-1.4-1.51.31.6-1.81.50.10.31.2
Short access day 1 total inactive lever presses1.11.23.2-1.01.01.1-1.2-0.51.20.6-1.41.30.50.61.8
Short access day 10 total inactive lever presses0.50.60.9-0.90.80.9-0.8-0.20.80.1-0.90.81.00.90.7
Short access day 1 total infusions1.51.63.2-1.31.21.4-1.5-1.01.51.0-1.81.60.20.31.6
Short access day 10 total infusions0.80.92.6-0.80.80.9-1.0-1.61.01.5-1.10.9-0.3-0.30.4
Short access total infusions2.12.44.4-1.41.41.6-1.7-1.81.71.7-2.11.8-0.3-0.21.5
Short access day 1 locomotion0.30.30.6-0.40.40.6-0.5-0.50.60.4-0.60.5-0.8-0.60.5
Short access day 10 total locomotion0.20.30.9-0.30.30.5-0.30.30.3-0.7-0.40.1-0.9-0.6-0.9
Short access total locomotion1.21.22.5-1.11.11.3-1.3-1.21.31.0-1.61.3-0.5-0.30.4
One hour access (0.3 mA shock)0.40.40.70.7-0.7-0.80.60.7-0.6-0.70.2-0.5-0.5-0.5-0.9
Compulsive drug intake2.62.64.52.0-2.0-2.11.91.9-1.9-1.51.6-1.6-0.7-0.9-0.1
One hour access (shock baseline)0.20.30.8-0.50.50.5-0.5-0.70.50.5-0.60.4-0.00.1-0.9
Social response proportion0.30.30.7-0.50.50.8-0.5-0.60.60.2-0.30.2-0.7-0.80.4
Social responses0.10.10.20.2-0.2-0.20.30.5-0.3-0.30.3-0.30.20.20.0
Social time2.22.93.91.7-1.7-1.71.71.6-1.6-1.71.5-1.6-2.0-1.8-1.7
Soleus weight0.20.71.31.0-1.0-1.00.81.1-0.8-0.80.7-0.5-0.9-0.90.3
Bone: stiffness1.52.43.4-1.61.61.8-1.8-1.81.71.7-1.81.60.40.51.4
Tibialis anterior weight0.72.54.31.7-1.7-1.51.51.5-1.5-1.61.5-1.5-1.8-2.1-1.1
Time to tail flick, vehicle, before self-admin0.10.10.4-0.10.1-0.0-0.0-0.1-0.00.10.20.00.40.60.4
Time to tail flick, vehicle, after self-admin1.01.12.80.6-0.6-0.81.01.1-1.0-1.11.2-1.10.91.0-1.7
Time to tail flick, test, before self-admin0.20.20.8-0.30.30.0-0.1-0.10.10.3-0.00.20.90.8-0.9
Time to tail flick, test, after self-admin1.21.22.31.1-1.1-1.11.21.2-1.2-1.21.1-1.2-0.4-0.6-1.5
Delta time to tail flick, vehicle, before/after SA0.10.10.70.2-0.2-0.10.20.3-0.2-0.50.2-0.3-0.3-0.3-0.8
Delta time to tail flick, test, before/after SA2.52.33.51.6-1.6-1.51.61.8-1.6-1.91.6-1.7-1.0-1.1-1.0
Tibia length0.72.02.8-1.31.31.2-1.4-1.51.31.7-1.61.51.61.41.3
Ambulatory time before self-admin0.40.41.80.4-0.4-0.20.10.8-0.1-0.7-0.30.1-1.3-1.30.4
Ambulatory time after self-admin0.60.61.60.8-0.8-0.80.71.3-0.8-1.10.4-0.6-0.3-0.4-0.7
Bone: tissue strength0.10.10.2-0.30.30.3-0.3-0.40.30.4-0.40.30.40.40.4
Total heroin consumption0.10.20.70.2-0.2-0.1-0.0-0.1-0.00.3-0.00.1-0.8-0.80.6
Bone: trabecular number0.10.10.4-0.20.20.1-0.1-0.20.00.3-0.10.00.60.6-0.5
Bone: trabecular spacing0.81.12.0-0.90.91.0-1.1-1.21.11.3-1.41.20.30.31.0
Bone: trabecular thickness0.10.10.30.1-0.1-0.00.30.3-0.2-0.50.5-0.4-0.3-0.4-0.2
Bone: trabecular tissue density1.42.03.11.4-1.4-1.11.31.3-1.2-1.61.7-1.5-1.7-1.8-0.4
Water consumed over 24 hours0.50.60.9-0.70.70.7-0.8-0.70.80.9-0.80.90.80.70.6
Number of responses in last shaping day1.61.66.11.1-1.1-0.80.80.9-0.8-1.00.8-0.8-2.5-2.4-0.6