Hub : Genes

Ddx17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Ddx17 0.04 0.03 1.3e-03 0.04 0.02 0.02 0.03 3.1e-04 4.6e-03 3.3e-03 1.6e-03
2 Adipose mRNA stability Ddx17 0.03 0.02 5.5e-03 0.02 0 0.01 0.01 4.9e-03 1.2e-01 1.5e-02 4.9e-02
3 LHb intron excision ratio chr7_112975405_112978128 0.18 0.09 2.1e-03 0.07 0.07 0.03 0.07 1.1e-02 9.8e-03 8.0e-02 9.5e-03
4 Brain intron excision ratio chr7_112975405_112978128 0.04 0.02 1.2e-03 0.03 0.02 0.01 0.01 1.9e-03 5.0e-03 2.9e-02 2.5e-02
5 Brain gene expression Ddx17 0.37 0.12 0.0e+00 0.24 0.23 0.24 0.24 3.7e-22 8.3e-21 6.9e-22 7.9e-22
6 PL gene expression Ddx17 0.03 0.02 2.8e-03 0.02 0.02 0.01 0.02 4.7e-03 5.1e-03 1.0e-02 6.0e-03
7 Adipose gene expression Ddx17 0.16 0.07 5.6e-17 0.15 0.16 0.16 0.16 2.5e-16 7.3e-17 3.8e-17 2.7e-17
8 Adipose intron excision ratio chr7_112975405_112978128 0.07 0.04 1.5e-06 0.06 0.04 0.04 0.04 3.5e-07 2.3e-05 8.8e-05 1.6e-05
9 LHb gene expression Ddx17 0.34 0.13 4.2e-05 0.16 0.12 0.17 0.11 1.4e-04 1.1e-03 6.8e-05 1.6e-03
10 Eye mRNA stability Ddx17 0.57 0.17 5.5e-03 0.03 0.02 -0.01 0.09 1.2e-01 1.8e-01 4.9e-01 1.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.00.00.10.00.0-0.00.1-0.1-0.10.10.2-0.10.3
Area under the delay curve3.45.27.62.52.6-2.72.7-2.4-1.82.62.5-1.7-0.1
BMI with tail0.72.43.3-1.7-1.61.8-1.71.71.4-1.8-1.61.2-0.7
BMI without tail0.31.82.6-1.6-1.51.6-1.41.51.0-1.6-0.91.3-0.3
Body weight2.29.613.1-3.5-3.53.6-3.53.53.6-3.4-2.41.90.9
Weight adjusted by age0.30.93.2-1.0-0.90.7-1.00.90.5-0.8-0.41.8-0.4
Bone surface0.10.20.60.30.4-0.40.4-0.4-0.00.40.8-0.50.3
Bone volume0.00.00.10.10.2-0.20.2-0.2-0.20.10.2-0.30.3
Breakpoint value in progressive ratio session0.10.30.70.40.8-0.80.6-0.30.10.30.2-0.80.2
Number of licking bursts0.31.11.91.11.1-1.11.1-1.0-1.41.21.2-0.4-0.2
Context. condit. distance diff. score7.99.613.6-3.2-3.63.6-3.73.22.3-3.4-3.33.0-0.3
Locomotion velocity, session 10.20.31.30.3-0.0-0.20.5-0.30.40.71.2-0.40.3
Locomotion distance, session 14.65.910.62.52.6-2.72.7-2.4-2.42.63.3-1.6-0.4
Locomotion velocity, session 20.10.21.20.40.1-0.1-0.0-0.4-0.10.2-0.1-0.3-1.1
Locomotion distance, session 26.18.612.93.13.1-3.23.1-3.1-2.23.33.6-2.90.3
Locomotion velocity, session 32.73.06.8-1.9-1.81.9-1.81.90.8-1.6-1.42.6-1.0
Locomotion distance, session 30.50.52.20.10.4-0.30.40.1-1.50.10.31.2-1.1
Stereotopy head waving bouts, day 30.40.41.7-0.4-0.60.6-0.50.31.3-0.2-0.2-0.41.1
Stereotopy head waving duration, day 31.92.36.1-1.4-1.91.7-1.61.32.5-1.2-1.30.40.8
Locomotion velocity, session 70.50.52.3-0.5-0.60.6-0.60.40.3-0.6-1.50.70.4
Locomotion distance, session 70.30.32.70.5-0.0-0.1-0.0-0.40.30.4-0.0-0.31.7
Stereotopy head waving bouts, day 74.35.07.4-2.4-2.32.2-2.02.31.5-2.5-2.42.7-1.7
Stereotopy head waving duration, day 74.15.17.9-2.3-2.22.2-2.02.21.2-2.5-2.62.8-2.0
Locomotion velocity, session 81.61.94.3-1.3-1.51.4-1.61.52.1-1.4-1.30.6-0.2
Locomotion distance, session 80.81.12.0-0.9-1.31.2-1.40.90.5-1.1-0.71.4-0.4
Degree of sensitization distance1.61.85.8-0.5-1.21.0-1.00.52.4-0.6-1.2-0.62.4
Degree of sensitization stereotypy3.64.17.2-2.1-1.91.8-1.62.11.2-2.2-2.22.7-2.2
Conditioned locomotion0.60.71.1-0.7-1.01.0-1.00.60.8-0.9-0.80.70.5
Cocaine response after cond. corrected0.10.10.50.30.2-0.20.1-0.20.70.40.4-0.20.6
Cocaine response after cond. not corrected0.10.10.30.20.2-0.10.0-0.20.60.20.3-0.20.3
Cocaine response before conditioning0.10.10.9-0.00.1-0.0-0.0-0.1-0.7-0.1-0.20.1-0.9
Saline control response1.11.52.1-1.3-1.41.5-1.51.20.8-0.9-1.21.4-0.2
Bone: connectivity density0.10.20.6-0.4-0.50.5-0.50.30.6-0.40.1-0.10.8
Bone: cortical apparent density0.50.82.3-0.7-0.90.9-0.90.8-0.8-0.6-0.51.5-0.8
Bone: cortical area0.20.31.40.00.0-0.0-0.0-0.20.80.4-0.3-1.20.7
Bone: cortical porosity0.30.41.8-0.3-0.00.1-0.20.41.3-0.4-1.1-0.50.4
Bone: cortical porosity0.70.73.9-0.5-0.30.4-0.40.62.0-0.5-1.2-0.60.6
Bone: cortical thickness0.71.13.30.91.1-1.01.0-1.0-0.61.40.4-1.80.3
Bone: cortical thickness2.12.65.31.71.4-1.41.4-1.7-1.22.01.8-2.30.3
Bone: cortical tissue density0.50.72.3-0.7-0.90.9-0.90.8-0.7-0.6-0.51.5-0.7
Condit. Reinf. active minus inactive responses0.10.10.60.10.1-0.10.4-0.2-0.30.30.5-0.30.8
Condit. Reinf. active-inactive response ratio0.20.30.5-0.6-0.60.7-0.40.5-0.0-0.4-0.50.70.2
Condit. Reinf. active responses0.20.20.80.10.2-0.20.4-0.2-0.90.10.8-0.00.7
Condit. Reinf. inactive responses0.20.20.90.20.2-0.30.3-0.2-0.9-0.20.80.20.4
Incentive salience index mean0.20.31.10.30.3-0.30.6-0.4-0.60.30.7-0.41.1
Condit. Reinf. lever presses0.20.31.30.20.3-0.30.4-0.3-0.60.10.5-0.41.2
Condit. Reinf. active minus inactive responses0.81.32.81.31.0-1.01.0-1.1-0.11.41.7-1.40.6
Condit. Reinf. active-inactive response ratio0.30.51.30.60.4-0.40.4-0.50.50.71.1-1.00.8
Condit. Reinf. active responses0.60.81.41.00.8-0.80.8-0.90.21.11.1-1.20.3
Condit. Reinf. inactive responses0.40.61.10.81.0-1.01.0-0.9-0.40.80.2-0.8-0.2
Condit. Reinf. lever presses0.40.61.21.10.8-0.80.8-1.1-0.70.50.8-0.70.5
Condit. Reinf. lever reinforcers received0.50.71.31.00.7-0.70.7-1.00.31.01.0-1.20.5
Conditioned reinforcement - actives0.83.34.52.12.0-1.81.8-2.1-1.22.11.8-2.10.0
Conditioned reinforcement - inactives2.05.411.12.62.5-2.42.3-2.4-1.22.42.2-3.31.1
Conditioned locomotion1.52.26.71.41.5-1.21.2-1.70.01.71.5-2.60.4
Patch foraging indifference point 0 sec0.20.52.4-0.5-0.60.7-0.70.10.7-0.10.5-0.31.6
Patch foraging indifference point AUC1.33.14.62.11.9-1.92.0-1.8-1.42.11.8-1.20.7
Delay disc. indifference point, 0s delay0.10.10.40.10.2-0.20.2-0.00.50.2-0.1-0.60.4
Delay disc. indifference point, 16s delay4.05.68.52.52.8-2.92.8-2.4-1.82.62.6-1.6-0.2
Delay disc. indifference point, 2s delay6.77.49.72.93.0-3.12.9-2.8-2.42.92.6-2.4-1.9
Delay disc. indifference point, 24s delay0.50.81.80.91.0-1.21.0-0.8-0.31.21.4-0.00.5
Delay disc. indifference point, 4s delay2.32.43.51.61.7-1.91.9-1.6-1.11.91.8-0.9-0.2
Delay disc. indifference point, 8s delay2.13.64.62.12.1-2.12.1-2.0-1.62.12.0-1.70.7
Indifference point function ln k1.64.86.3-2.4-2.42.4-2.52.31.9-2.4-2.21.8-0.8
Indifference point function log k1.64.86.3-2.4-2.42.4-2.52.31.9-2.4-2.21.8-0.8
Patch foraging total patch changes 0 sec0.10.31.7-0.1-0.40.4-0.5-0.20.30.20.8-0.41.3
Patch foraging total patch changes 12 sec0.50.61.10.80.6-0.50.5-0.90.11.00.8-1.11.0
Patch foraging total patch changes 18 sec0.92.14.11.31.3-1.21.5-1.30.11.41.4-2.02.0
Patch foraging total patch changes 24 sec0.20.81.91.00.7-0.70.6-1.0-0.71.10.9-1.40.6
Patch foraging total patch changes 6 sec1.01.72.91.31.0-1.01.1-1.5-0.31.71.6-1.61.3
Patch foraging time to switch 0 sec0.00.10.30.50.5-0.50.6-0.50.10.0-0.1-0.3-0.4
Patch foraging water rate 0 sec0.20.92.8-0.8-1.11.1-1.20.80.8-0.40.10.11.7
Patch foraging water rate 12 sec0.10.51.2-0.9-0.90.9-1.10.70.0-0.5-0.50.2-0.3
Patch foraging water rate 18 sec0.10.30.8-0.9-0.70.6-0.70.80.5-0.2-0.10.30.4
Patch foraging water rate 24 sec2.53.65.0-2.2-2.22.2-2.11.92.0-1.9-1.81.40.7
Patch foraging water rate 6 sec0.40.61.4-1.2-0.70.8-0.91.10.1-0.9-0.50.80.4
Seeking ratio, delayed vs. immediate footshock0.30.41.10.50.5-0.60.6-0.4-1.10.30.30.6-0.6
Distance traveled before self-admin1.02.25.12.31.4-1.41.5-2.0-1.21.61.4-1.10.1
Distance traveled after self-admin0.50.93.60.60.6-0.50.5-0.70.70.61.2-1.21.9
Extensor digitorum longus weight0.41.53.41.01.2-1.21.2-1.0-1.81.11.4-0.5-1.4
Bone: elastic displacement0.40.50.8-0.7-0.90.8-0.80.70.7-0.6-0.30.8-0.1
Bone: elastic work0.60.73.4-0.6-0.90.8-0.80.51.8-0.3-0.5-0.20.8
Bone: endosteal estimation0.30.73.5-0.5-0.80.8-0.80.31.9-0.7-0.5-0.10.9
Bone: endosteal perimeter0.41.13.4-1.0-1.00.9-1.00.91.9-1.0-1.20.20.3
Epididymis fat weight1.89.112.3-3.3-3.43.5-3.53.03.3-3.2-3.31.40.4
Delta time in closed arm before/after self-admin0.90.82.10.90.8-0.70.7-0.8-0.41.30.8-1.40.7
Delta time in open arm before/after self-admin0.10.10.30.10.2-0.30.3-0.2-0.0-0.10.50.6-0.4
Diff in mean of infusions in LGA sessions0.00.10.5-0.2-0.0-0.10.0-0.00.70.00.1-0.20.5
Delay discount exponential model param3.85.27.5-2.5-2.62.7-2.72.31.8-2.5-2.51.60.1
Extinction: sum of active levers before priming0.91.42.71.21.6-1.61.4-1.0-0.21.31.1-0.9-0.7
Active lever presses in extinction session 60.10.10.30.10.2-0.30.2-0.50.10.20.20.5-0.4
Bone: final force0.30.51.70.40.3-0.20.2-0.50.90.60.2-1.31.1
Bone: final moment0.30.51.60.30.1-0.10.0-0.41.10.60.2-1.21.3
Food consumed during 24 hour testing period0.10.31.1-0.10.4-0.30.20.11.00.3-0.4-1.00.5
Glucose0.40.62.7-0.40.00.1-0.10.51.0-0.6-0.3-1.11.6
Heart weight2.03.29.5-1.8-1.91.8-1.61.83.1-1.7-1.60.50.9
Delay discount hyperbolic model param4.35.57.7-2.5-2.72.8-2.72.41.9-2.6-2.61.70.4
Intermittent access intake day 1-15 change0.00.10.2-0.2-0.10.2-0.20.2-0.2-0.40.20.1-0.5
Intermittent access intake escalation0.00.10.4-0.2-0.10.1-0.10.2-0.4-0.40.30.4-0.6
Intermittent access intake escalation 20.00.10.1-0.3-0.20.3-0.20.1-0.3-0.40.10.2-0.3
Intermitt. access day 1 inactive lever presses0.10.84.30.30.1-0.20.20.01.4-0.1-0.4-1.22.1
Intermitt. access day 15 inactive lever presses0.20.91.81.10.8-1.00.9-0.9-0.30.80.8-1.11.3
Intermitt. access escalation Index0.10.21.10.40.5-0.30.3-0.0-0.60.2-0.30.0-1.1
Intermittent access day 1 total infusions1.64.77.72.52.5-2.42.3-2.3-0.82.41.8-2.80.7
Intermittent access day 15 total infusions1.22.93.92.01.9-1.81.9-1.8-1.31.72.0-1.6-0.1
Intermittent access terminal intake (last 3 days)1.72.94.22.11.9-1.81.9-1.9-1.31.81.8-1.6-0.1
Intermittent access total infusions5.46.49.03.02.8-2.72.8-2.8-1.22.82.4-3.00.6
Intermittent access day 1 locomotion1.63.05.52.01.9-1.81.8-1.9-0.71.91.5-2.41.0
Intermittent access day 15 total locomotion0.41.44.41.21.2-1.11.1-1.1-0.21.00.8-2.11.1
Intermittent access total locomotion1.41.76.01.21.2-1.01.0-1.10.21.10.6-2.41.8
Intermittent access standard deviation0.42.05.91.11.2-1.01.1-1.40.91.11.2-2.42.0
Left kidney weight2.217.542.6-4.3-4.54.4-4.34.56.5-3.8-4.01.71.0
Right kidney weight3.524.258.8-5.2-5.15.1-5.05.27.7-4.8-4.51.72.2
Cocaine induced anxiety0.20.71.1-0.9-0.91.0-1.00.80.6-0.9-1.00.1-0.3
Post-drug Anxiety1.61.83.2-1.5-1.71.8-1.61.50.4-1.4-1.31.2-0.1
Baseline Anxiety0.20.31.10.50.3-0.20.4-0.6-1.10.70.80.30.2
Tail length0.42.13.4-1.8-1.71.7-1.41.81.2-1.6-0.81.21.0
Length with tail1.87.810.7-3.3-3.33.2-3.03.23.1-2.9-1.81.91.3
Length without tail1.36.715.5-2.7-2.92.8-2.82.73.9-2.3-1.90.91.7
Times rat made contact with spout0.40.41.80.20.5-0.40.3-0.1-0.10.70.7-1.11.3
Lifetime Intake5.97.311.63.13.0-2.92.9-3.0-1.03.02.4-3.41.0
Liver weight, left0.81.42.7-1.2-1.21.3-1.31.00.4-1.2-1.71.3-0.7
Liver weight, right6.110.617.8-3.8-3.23.4-3.23.72.3-3.7-4.23.0-0.5
Locomotor activity1.42.23.6-1.8-1.61.7-1.81.61.9-1.4-1.40.70.1
Locomotor testing distance0.00.10.2-0.4-0.20.4-0.50.30.1-0.2-0.20.00.2
Locomotor testing rearing0.20.61.2-0.9-0.70.9-0.80.71.1-0.6-1.1-0.10.4
Locomotion in novel chamber0.50.73.4-0.10.2-0.10.10.1-1.6-0.30.11.1-1.8
Locomotion in novel chamber post-restriction0.61.73.61.21.5-1.51.5-1.1-1.90.90.9-0.5-1.5
Fecal boli incidents, locomotor time 10.71.85.01.21.2-1.21.2-1.2-0.21.31.0-1.62.2
Change in fecal boli incidents, locomotor task1.82.03.5-1.6-1.61.7-1.91.40.8-1.3-1.21.2-0.9
Time >=10cm from walls, locomotor time 10.30.41.4-0.7-0.50.5-0.60.51.2-0.4-0.30.11.0
Bouts of movement, locomotor time 10.30.40.9-0.7-0.30.3-0.50.60.8-0.5-0.90.90.5
Total resting periods, locomotor time 10.10.20.5-0.3-0.10.0-0.20.10.6-0.1-0.50.60.7
Rest time, locomotor task time 10.20.41.7-0.2-0.00.10.1-0.10.9-0.1-0.7-0.81.3
Distance moved, locomotor task time 10.41.22.0-0.9-1.41.3-1.41.00.3-1.0-0.51.1-1.4
Vertical activity count, locomotor time 10.21.32.3-1.2-1.41.5-1.51.31.0-1.2-0.60.60.6
Time >=10cm from walls, locomotor time 20.20.40.9-0.8-0.50.5-0.40.60.9-0.7-0.50.80.9
Bouts of movement, locomotor time 20.20.82.80.70.9-0.90.8-0.7-1.00.3-0.7-0.2-1.7
Total resting periods, locomotor time 20.31.22.21.11.3-1.31.2-1.0-1.10.8-0.2-0.8-1.5
Rest time, locomotor task time 20.50.83.50.70.9-0.70.9-0.8-0.20.80.6-1.90.8
Distance moved, locomotor task time 20.91.21.7-1.2-1.31.1-1.31.20.9-1.2-0.81.3-0.2
Vertical activity count, locomotor time 20.51.11.6-1.2-0.90.9-1.01.21.3-1.2-0.90.01.0
Light reinforcement 10.00.10.30.20.1-0.20.1-0.3-0.30.50.5-0.20.3
Light reinforcement 20.30.71.9-0.8-0.50.6-0.70.60.3-0.9-1.41.1-0.9
Bone: marrow area0.30.83.7-0.5-0.90.8-0.80.31.9-0.7-0.5-0.11.0
Bone: maximum diameter0.61.25.2-1.0-1.00.9-1.00.82.3-0.6-1.0-0.60.9
Bone: maximum force0.50.93.50.50.4-0.30.3-0.61.30.80.3-1.91.5
Bone: maximum moment0.50.93.10.30.2-0.20.1-0.51.50.70.3-1.81.5
Mean time between licks in bursts0.21.02.80.90.6-0.70.7-0.9-1.20.91.00.9-1.7
Mean num. licks in bursts0.41.01.8-1.1-1.01.0-1.11.11.3-0.9-0.9-0.10.9
Cd content in liver0.40.50.9-0.8-0.80.9-1.00.80.4-0.5-0.00.1-0.7
Co content in liver0.70.91.61.20.8-0.90.5-1.2-0.81.21.3-0.80.2
Cu content in liver3.34.07.92.12.0-2.12.2-2.0-2.81.72.5-1.1-0.4
Fe content in liver2.63.38.2-1.8-2.01.9-1.81.82.9-1.9-1.21.50.2
K content in liver0.10.10.30.40.3-0.30.3-0.4-0.50.20.50.30.4
Mg content in liver0.20.20.50.50.4-0.40.4-0.5-0.30.20.6-0.70.7
Mn content in liver0.20.20.50.20.7-0.50.4-0.3-0.70.2-0.4-0.2-0.3
Na content in liver0.10.10.30.0-0.00.0-0.1-0.1-0.2-0.40.4-0.50.6
Rb content in liver0.60.71.41.20.6-0.70.7-1.1-0.51.11.2-0.50.4
Se content in liver0.40.52.4-0.9-0.30.4-0.20.8-0.5-0.70.10.1-1.5
Sr content in liver2.11.86.41.21.4-1.31.1-1.2-2.50.91.1-1.1-0.6
Zn content in liver0.10.10.4-0.1-0.20.2-0.20.1-0.2-0.10.60.10.1
Bone: minimum diameter0.10.31.00.10.1-0.10.1-0.31.00.1-0.4-1.00.8
Time in familiar zone, hab. session 10.20.30.50.60.5-0.50.5-0.7-0.30.70.6-0.40.2
Time in novel zone, hab. session 11.41.52.2-1.4-1.31.3-1.51.51.3-1.3-1.20.8-0.4
Total zone transitions, hab. session 11.11.55.00.70.9-0.91.0-0.6-2.20.91.70.8-1.5
Total locomotion distance, hab. session 10.20.41.3-0.2-0.10.10.10.3-1.2-0.10.50.9-1.0
Locomotion velocity, hab. session 10.30.52.10.30.4-0.40.7-0.2-1.40.31.00.5-0.6
Time in familiar zone, hab. session 20.30.40.9-0.4-0.30.4-0.60.3-0.8-0.5-0.50.9-0.8
Time in novel zone, hab. session 20.40.51.80.30.4-0.40.5-0.30.90.50.6-1.30.9
Total zone transitions, hab. session 21.72.25.61.51.4-1.51.4-1.6-1.31.62.4-1.20.6
Total locomotion distance, hab. session 21.41.93.31.51.3-1.41.5-1.5-0.91.51.8-1.30.6
Locomotion velocity, hab. session 21.82.54.51.71.5-1.61.7-1.7-1.11.72.1-1.30.8
Novel to familiar place preference ratio2.83.65.3-2.2-2.22.2-2.32.31.7-2.0-1.11.6-0.9
Novelty place preference3.74.76.9-2.5-2.52.5-2.52.61.9-2.3-1.41.9-1.1
Time in novel zone, NPP test4.55.57.9-2.7-2.62.7-2.72.82.1-2.5-1.52.0-1.2
Total zone transitions, NPP test1.52.25.91.41.3-1.41.3-1.3-2.11.52.4-0.3-0.6
Total locomotion distance, NPP test0.71.02.91.10.8-0.90.8-1.1-1.11.21.7-0.30.2
Locomotion velocity, NPP test1.21.73.11.41.2-1.31.2-1.5-1.71.61.8-0.40.0
Intraocular pressure0.20.40.6-0.7-0.70.7-0.70.50.7-0.6-0.50.2-0.4
Delta distance traveled before/after self-admin2.02.24.6-2.1-1.11.2-1.41.72.1-1.3-0.70.31.7
Delta ambulatory time before/after self-admin0.91.64.3-1.7-0.90.9-1.21.32.1-0.9-0.20.11.8
Parametrial fat weight1.22.84.7-2.1-1.71.8-1.61.91.0-1.8-2.21.70.2
Pavlov. Cond. lever latency0.10.20.5-0.3-0.60.5-0.70.20.2-0.2-0.10.5-0.1
Pavlov. Cond. magazine entry latency1.82.43.91.72.0-1.91.8-1.6-1.21.61.3-1.4-0.2
Pavlov. Cond. change in total contacts3.74.05.92.22.4-2.42.4-2.1-1.52.11.7-1.90.3
Pavlov. Cond. index score1.01.32.11.21.4-1.41.4-1.1-0.51.10.8-1.40.5
Pavlov. Cond. latency score0.50.71.30.81.1-1.01.0-0.7-0.30.70.5-1.10.3
Pavlov. Cond. lever contacts0.80.91.81.01.3-1.21.3-0.9-0.70.80.6-1.00.5
Pavlov. Cond. magazine entry number2.22.73.9-1.8-2.01.9-1.81.81.5-1.8-1.41.4-0.1
Pavlov. Cond. intertrial magazine entries0.20.31.30.1-0.1-0.00.1-0.1-0.10.31.1-0.11.1
Pavlov. Cond. lever-magazine prob. diff.1.01.32.11.21.5-1.41.4-1.1-0.81.10.8-1.20.3
Pavlov. Cond. response bias1.92.33.51.71.9-1.81.8-1.6-1.21.51.2-1.50.3
Pavlov. Cond. lever latency0.10.11.0-0.2-0.00.1-0.10.3-0.20.1-0.20.2-1.0
Pavlov. Cond. magazine entry latency1.62.34.11.61.4-1.51.5-1.6-0.71.72.0-1.61.3
Pavlov. Cond. change in total contacts0.41.05.30.2-0.30.1-0.1-0.11.80.20.5-1.12.3
Pavlov. Cond. index score0.50.82.30.80.6-0.70.7-0.80.00.71.1-0.91.5
Pavlov. Cond. latency score0.61.02.81.00.7-0.80.9-1.0-0.11.01.4-1.01.7
Pavlov. Cond. lever contacts0.10.11.00.1-0.10.0-0.0-0.20.2-0.20.2-0.11.0
Pavlov. Cond. magazine entry number0.40.51.2-0.7-0.40.5-0.50.70.0-0.8-1.10.6-1.0
Pavlov. Cond. intertrial magazine entries0.10.20.80.30.4-0.30.3-0.30.2-0.0-0.6-0.60.9
Pavlov. Cond. lever-magazine prob. diff.0.40.61.80.80.5-0.60.6-0.80.00.71.0-0.81.3
Pavlov. Cond. response bias0.30.51.30.70.5-0.60.6-0.80.00.50.7-0.81.2
Time in closed arm before self-admin0.30.51.00.50.8-1.00.8-0.9-0.80.60.7-0.70.3
Time in closed arm after self-admin0.30.31.7-0.1-0.1-0.1-0.1-0.00.40.2-0.4-0.91.3
Time in open arm before self-admin0.20.20.5-0.4-0.50.7-0.50.5-0.1-0.4-0.60.00.3
Time in open arm after self-admin0.30.30.9-0.2-0.20.5-0.30.3-0.5-0.4-0.11.0-0.9
Bone: periosteal estimation0.20.62.9-0.3-0.50.5-0.50.11.7-0.3-0.5-0.70.9
Bone: periosteal perimeter0.91.75.7-1.3-1.31.3-1.31.12.4-1.0-1.4-0.20.7
Bone: post-yield work0.81.33.61.11.0-1.01.0-1.2-0.11.21.4-1.90.5
Progressive ratio test 1 active lever presses2.84.96.62.62.5-2.42.4-2.5-0.72.52.2-2.50.6
Progressive ratio test 1 breakpoint2.74.66.32.52.4-2.42.3-2.5-0.82.52.2-2.30.5
Progressive ratio test 1 inactive lever presses2.25.99.43.02.6-2.82.6-2.6-0.72.62.0-3.10.9
Progressive ratio test 2 active lever presses3.54.97.82.72.6-2.42.5-2.3-1.12.41.7-2.80.8
Progressive ratio test 2 breakpoint4.25.47.82.82.7-2.62.6-2.4-1.22.51.9-2.70.6
Progressive ratio test 2 inactive lever presses1.64.97.32.72.6-2.62.5-2.3-1.82.11.7-2.30.4
Incentive Sensitization - Responses0.30.81.41.11.2-1.11.1-0.7-0.80.80.3-1.00.2
Incentive Sensitization - Breakpoint0.40.81.51.11.2-1.11.2-0.7-0.70.80.2-1.10.2
Sum of active levers in priming session hrs 5-60.00.00.1-0.2-0.10.1-0.20.20.2-0.30.10.1-0.3
Progressive ratio0.00.10.50.1-0.1-0.00.2-0.10.40.20.5-0.30.7
Food seeking constrained by brief footshock0.20.20.80.50.1-0.20.3-0.5-0.00.60.4-0.9-0.5
Seeking ratio, punishment vs. effort0.10.20.50.40.4-0.30.2-0.4-0.20.4-0.1-0.7-0.5
Retroperitoneal fat weight2.812.718.9-4.0-3.73.8-3.83.94.3-3.5-4.31.80.3
Reaction time number correct0.20.72.9-0.00.5-0.40.50.2-1.3-0.2-0.81.1-1.7
Reaction time mean minus median0.00.00.2-0.10.1-0.10.10.20.4-0.40.30.00.0
Reaction time mean minus median AUC0.10.50.9-0.8-0.60.6-0.70.80.8-1.0-0.70.3-0.0
Reaction time num false alarms0.20.40.6-0.8-0.60.7-0.80.80.7-0.4-0.30.2-0.8
Reaction time num false alarms AUC0.20.41.0-0.7-0.70.8-0.90.70.5-0.3-0.20.4-1.0
Reaction time trials correct on left0.20.72.9-0.00.5-0.40.50.2-1.3-0.2-0.81.1-1.7
Reaction time trials on left0.20.73.10.00.6-0.40.60.2-1.4-0.2-0.71.0-1.7
Reaction time mean0.10.20.6-0.3-0.50.4-0.40.30.5-0.80.00.40.3
Reaction time mean AUC0.10.10.5-0.2-0.40.3-0.30.30.4-0.70.10.40.2
Median of all reaction times0.10.10.4-0.1-0.50.4-0.30.10.3-0.70.20.50.2
Reaction time omissions1.11.73.31.21.8-1.71.6-1.2-1.41.21.0-0.7-1.0
Reaction time false alarm rate0.30.41.0-0.6-0.80.9-1.00.50.9-0.30.00.1-0.3
Reaction time premature initiation rate0.50.73.50.20.5-0.50.4-0.21.00.40.3-1.91.2
Reaction time premature initiations0.10.31.40.10.6-0.50.50.00.50.1-0.2-1.20.4
Std. dev. reaction times0.20.61.4-0.8-0.60.6-0.61.01.2-1.1-0.50.30.2
Reaction time trials completed0.20.73.10.00.6-0.40.60.2-1.4-0.2-0.71.0-1.7
Reaction time trials AUC0.20.62.6-0.20.3-0.20.30.3-1.0-0.3-0.91.0-1.6
Run reversals in cocaine runway, females0.80.91.5-1.1-1.20.9-0.91.20.3-1.0-1.11.1-0.5
Run reversals in cocaine runway, males0.10.20.70.0-0.40.3-0.2-0.20.10.30.90.60.2
Latency to leave start box in cocaine runway0.40.51.8-0.5-0.30.4-0.30.70.5-0.6-0.71.3-1.2
Latency to leave start box in cocaine runway, F0.20.20.80.50.2-0.20.3-0.3-0.20.30.60.8-0.9
Latency to leave start box in cocaine runway, M1.91.84.1-1.6-0.91.1-1.01.61.1-1.5-2.01.3-0.8
Std. dev. time between licks in bursts0.20.31.00.7-0.0-0.20.2-0.6-0.30.81.00.60.5
Total sessions with >9 infusions2.02.55.51.71.7-1.51.6-1.70.61.71.0-2.31.1
Short access day 1 total inactive lever presses1.22.57.51.30.7-0.90.9-1.51.01.42.0-2.02.7
Short access day 10 total inactive lever presses0.21.74.3-0.9-1.21.1-1.11.21.6-1.2-1.40.12.1
Short access day 1 total infusions0.81.73.21.41.2-1.21.2-1.40.51.11.0-1.61.8
Short access day 10 total infusions1.11.84.51.61.4-1.41.4-1.50.31.50.8-2.10.5
Short access total infusions3.04.38.32.42.2-2.22.2-2.30.12.21.6-2.91.1
Short access day 1 locomotion0.40.71.70.90.7-0.70.6-0.90.70.60.7-1.01.3
Short access day 10 total locomotion0.51.86.01.21.3-1.21.1-0.90.50.80.4-2.22.5
Short access total locomotion1.01.54.01.21.2-1.11.0-1.20.71.00.6-2.01.6
One hour access (0.3 mA shock)7.48.811.93.33.5-3.23.3-3.3-2.83.12.7-2.8-0.3
Compulsive drug intake0.30.41.00.50.9-0.81.0-0.3-1.00.60.5-0.20.2
One hour access (shock baseline)1.02.63.92.01.7-1.61.7-1.9-1.31.71.5-1.7-0.6
Social response proportion0.10.20.8-0.20.4-0.40.40.20.60.20.30.1-0.9
Social responses0.60.81.90.60.9-0.90.9-0.9-0.51.31.4-0.7-0.3
Social time2.64.16.22.02.3-2.22.1-2.2-1.82.12.5-1.90.5
Soleus weight0.61.75.60.91.0-0.90.6-0.9-0.11.10.9-2.32.4
Bone: stiffness0.30.62.7-0.0-0.00.1-0.1-0.11.40.2-0.2-1.21.6
Tibialis anterior weight1.86.28.42.72.7-2.62.5-2.8-2.92.72.7-2.0-0.6
Time to tail flick, vehicle, before self-admin0.10.10.3-0.10.2-0.20.20.20.50.00.1-0.60.1
Time to tail flick, vehicle, after self-admin0.40.71.3-1.1-0.90.7-1.10.80.9-0.8-0.11.10.7
Time to tail flick, test, before self-admin0.40.41.40.50.5-0.50.4-0.4-0.80.7-0.4-0.5-1.2
Time to tail flick, test, after self-admin0.10.10.50.10.1-0.1-0.1-0.1-0.4-0.1-0.30.7-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.40.1-0.1-0.1-0.2-0.30.30.20.50.60.6
Delta time to tail flick, test, before/after SA0.20.31.8-0.2-0.20.3-0.30.0-0.5-0.60.41.3-0.0
Tibia length0.10.42.2-0.4-0.40.4-0.40.51.5-0.30.1-0.50.4
Ambulatory time before self-admin0.51.43.51.91.1-1.01.2-1.6-1.11.21.2-0.8-0.1
Ambulatory time after self-admin0.30.52.40.40.4-0.20.3-0.50.40.41.6-0.41.4
Bone: tissue strength0.40.50.7-0.8-0.70.8-0.80.80.8-0.6-0.50.40.1
Total heroin consumption1.31.52.31.11.5-1.51.3-1.3-0.61.51.3-1.2-0.1
Bone: trabecular number0.20.30.7-0.6-0.60.6-0.60.60.0-0.6-0.50.9-0.3
Bone: trabecular spacing0.40.52.00.50.4-0.40.3-0.60.80.50.2-1.41.2
Bone: trabecular thickness0.20.30.8-0.3-0.20.2-0.20.3-0.5-0.7-0.80.9-0.2
Bone: trabecular tissue density0.10.20.4-0.4-0.50.4-0.40.3-0.3-0.20.40.60.0
Water consumed over 24 hours0.20.42.3-0.00.3-0.20.2-0.10.40.70.6-1.01.5
Number of responses in last shaping day5.36.910.53.23.1-3.03.0-2.8-1.12.72.4-2.90.6