Ddx17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Ddx17 0.04 0.03 1.3e-03 0.04 0.02 0.02 0.03 3.1e-04 4.6e-03 3.3e-03 1.3e-03
2 Adipose mRNA stability Ddx17 0.03 0.02 5.5e-03 0.02 0 0.01 0.01 4.9e-03 1.2e-01 1.5e-02 5.2e-02
3 LHb intron excision ratio chr7_112975405_112978128 0.18 0.09 2.1e-03 0.07 0.07 0.03 0.07 1.1e-02 9.8e-03 8.0e-02 9.6e-03
4 Brain intron excision ratio chr7_112975405_112978128 0.04 0.02 1.2e-03 0.03 0.02 0.01 0.01 1.9e-03 5.0e-03 2.9e-02 2.6e-02
5 Brain gene expression Ddx17 0.37 0.12 0.0e+00 0.24 0.23 0.24 0.24 3.7e-22 8.3e-21 6.9e-22 7.7e-22
6 PL gene expression Ddx17 0.03 0.02 2.8e-03 0.02 0.02 0.01 0.02 4.7e-03 5.1e-03 1.0e-02 5.9e-03
7 Adipose gene expression Ddx17 0.16 0.07 5.6e-17 0.15 0.16 0.16 0.16 2.5e-16 7.3e-17 3.8e-17 2.8e-17
8 Adipose intron excision ratio chr7_112975405_112978128 0.07 0.04 1.5e-06 0.06 0.04 0.04 0.04 3.5e-07 2.3e-05 8.8e-05 1.5e-05
9 LHb gene expression Ddx17 0.34 0.13 4.2e-05 0.16 0.12 0.17 0.1 1.4e-04 1.1e-03 6.8e-05 2.1e-03
10 Eye mRNA stability Ddx17 0.57 0.17 5.5e-03 0.03 0.02 -0.01 0.09 1.2e-01 1.8e-01 4.9e-01 1.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.00.00.1-0.0-0.0-0.0-0.10.10.10.1-0.20.10.3
Area under the delay curve4.55.27.5-2.5-2.6-2.7-2.72.41.82.6-2.51.7-0.1
BMI with tail0.72.43.31.71.61.81.7-1.7-1.4-1.81.6-1.2-0.7
BMI without tail0.61.82.61.61.51.61.4-1.5-1.0-1.60.9-1.3-0.3
Body weight2.29.613.13.53.53.63.5-3.5-3.6-3.42.4-1.90.9
Weight adjusted by age0.60.93.21.00.90.71.0-0.9-0.5-0.80.4-1.8-0.4
Bone surface0.10.20.6-0.3-0.4-0.4-0.40.40.00.4-0.80.50.3
Bone volume0.00.00.1-0.1-0.2-0.2-0.20.20.20.1-0.20.30.3
Breakpoint value in progressive ratio session0.20.30.7-0.4-0.8-0.8-0.60.3-0.10.2-0.20.80.2
Number of licking bursts0.61.11.9-1.1-1.1-1.1-1.11.01.41.2-1.20.4-0.2
Context. condit. distance diff. score8.09.613.63.23.63.63.7-3.2-2.3-3.43.3-3.0-0.2
Locomotion velocity, session 10.30.31.3-0.30.0-0.2-0.50.3-0.40.7-1.20.40.3
Locomotion distance, session 14.75.910.6-2.5-2.6-2.7-2.72.42.42.6-3.31.6-0.4
Locomotion velocity, session 20.10.21.2-0.4-0.1-0.10.00.40.10.20.10.3-1.1
Locomotion distance, session 26.28.612.9-3.1-3.1-3.2-3.13.12.23.3-3.62.90.3
Locomotion velocity, session 32.73.06.81.91.81.91.8-1.9-0.8-1.61.4-2.6-1.0
Locomotion distance, session 30.50.52.2-0.1-0.4-0.3-0.4-0.11.50.0-0.3-1.2-1.1
Stereotopy head waving bouts, day 30.40.41.70.40.60.60.5-0.3-1.3-0.20.20.41.1
Stereotopy head waving duration, day 31.92.36.11.41.91.71.6-1.3-2.5-1.21.3-0.40.8
Locomotion velocity, session 70.50.52.30.50.60.60.6-0.4-0.3-0.61.5-0.70.5
Locomotion distance, session 70.30.32.8-0.50.0-0.10.00.4-0.30.40.00.31.7
Stereotopy head waving bouts, day 74.55.07.42.42.32.22.0-2.3-1.5-2.52.4-2.7-1.7
Stereotopy head waving duration, day 74.25.17.92.32.22.22.0-2.2-1.2-2.52.6-2.8-2.0
Locomotion velocity, session 81.61.94.31.31.51.41.6-1.5-2.1-1.41.3-0.6-0.2
Locomotion distance, session 80.81.12.00.91.31.21.4-0.9-0.5-1.10.7-1.4-0.4
Degree of sensitization distance1.71.85.80.51.21.01.0-0.5-2.4-0.61.20.62.4
Degree of sensitization stereotypy3.74.17.22.11.91.81.6-2.1-1.2-2.22.2-2.7-2.2
Conditioned locomotion0.60.71.10.71.01.01.0-0.6-0.8-0.90.8-0.70.5
Cocaine response after cond. corrected0.10.10.5-0.3-0.2-0.2-0.10.2-0.70.3-0.40.20.6
Cocaine response after cond. not corrected0.10.10.3-0.2-0.2-0.1-0.00.2-0.60.2-0.30.20.3
Cocaine response before conditioning0.10.10.90.0-0.1-0.00.00.10.7-0.10.2-0.1-0.9
Saline control response1.11.52.11.31.41.51.5-1.2-0.8-0.91.2-1.4-0.2
Bone: connectivity density0.10.20.60.40.50.50.5-0.3-0.6-0.4-0.10.10.8
Bone: cortical apparent density0.60.82.30.70.90.90.9-0.80.8-0.60.5-1.5-0.8
Bone: cortical area0.20.31.4-0.0-0.0-0.00.00.2-0.80.40.31.20.7
Bone: cortical porosity0.30.41.80.30.00.10.2-0.4-1.3-0.41.10.50.4
Bone: cortical porosity0.70.73.90.50.30.40.4-0.6-2.0-0.51.20.60.5
Bone: cortical thickness0.71.13.3-0.9-1.1-1.0-1.01.00.61.4-0.41.80.3
Bone: cortical thickness2.22.65.3-1.7-1.4-1.4-1.41.71.22.0-1.82.30.3
Bone: cortical tissue density0.50.72.30.70.90.90.9-0.80.7-0.60.5-1.5-0.7
Condit. Reinf. active minus inactive responses0.10.20.6-0.1-0.1-0.1-0.40.20.30.3-0.50.30.8
Condit. Reinf. active-inactive response ratio0.20.30.50.60.60.70.4-0.50.0-0.40.5-0.70.3
Condit. Reinf. active responses0.20.20.8-0.1-0.2-0.2-0.40.20.90.1-0.80.00.7
Condit. Reinf. inactive responses0.20.20.9-0.2-0.2-0.3-0.30.20.9-0.2-0.8-0.20.5
Incentive salience index mean0.20.31.2-0.3-0.3-0.3-0.60.40.60.3-0.70.41.1
Condit. Reinf. lever presses0.20.31.3-0.2-0.3-0.3-0.40.30.60.1-0.50.41.2
Condit. Reinf. active minus inactive responses1.01.32.8-1.3-1.0-1.0-1.01.10.11.4-1.71.40.6
Condit. Reinf. active-inactive response ratio0.40.51.3-0.6-0.4-0.4-0.40.5-0.50.7-1.11.00.8
Condit. Reinf. active responses0.60.81.4-1.0-0.8-0.8-0.80.9-0.21.1-1.11.20.3
Condit. Reinf. inactive responses0.50.61.1-0.8-1.0-1.0-1.00.90.40.8-0.20.8-0.3
Condit. Reinf. lever presses0.50.61.2-1.1-0.8-0.8-0.81.10.70.5-0.80.70.5
Condit. Reinf. lever reinforcers received0.50.71.3-1.0-0.7-0.7-0.71.0-0.31.0-1.01.20.5
Conditioned reinforcement - actives1.93.34.5-2.1-2.0-1.8-1.82.11.22.0-1.82.10.0
Conditioned reinforcement - inactives3.75.411.1-2.6-2.5-2.4-2.32.41.22.4-2.23.31.1
Conditioned locomotion1.72.26.7-1.4-1.5-1.2-1.21.7-0.01.7-1.52.60.4
Patch foraging indifference point 0 sec0.30.52.50.50.60.70.7-0.1-0.7-0.1-0.50.31.6
Patch foraging indifference point AUC2.13.14.6-2.1-1.9-1.9-2.01.81.42.1-1.81.20.7
Delay disc. indifference point, 0s delay0.10.10.4-0.1-0.2-0.2-0.20.0-0.50.30.10.60.4
Delay disc. indifference point, 16s delay5.15.68.5-2.5-2.8-2.9-2.82.41.82.6-2.61.6-0.2
Delay disc. indifference point, 2s delay6.77.49.7-2.9-3.0-3.1-2.92.82.42.9-2.62.4-1.9
Delay disc. indifference point, 24s delay0.70.81.8-0.9-1.0-1.2-1.00.80.31.1-1.40.00.5
Delay disc. indifference point, 4s delay2.32.43.5-1.6-1.7-1.9-1.91.61.11.9-1.80.9-0.2
Delay disc. indifference point, 8s delay3.03.64.6-2.1-2.1-2.1-2.12.01.62.1-2.01.70.7
Indifference point function ln k2.74.86.32.42.42.42.5-2.3-1.9-2.42.2-1.8-0.8
Indifference point function log k2.74.86.32.42.42.42.5-2.3-1.9-2.42.2-1.8-0.8
Patch foraging total patch changes 0 sec0.20.31.70.10.40.40.50.2-0.30.2-0.80.41.3
Patch foraging total patch changes 12 sec0.50.61.1-0.8-0.6-0.5-0.50.9-0.11.0-0.81.11.0
Patch foraging total patch changes 18 sec1.42.14.1-1.3-1.3-1.2-1.51.3-0.11.4-1.42.02.0
Patch foraging total patch changes 24 sec0.50.81.9-1.0-0.7-0.7-0.61.00.71.1-0.91.40.6
Patch foraging total patch changes 6 sec1.11.72.9-1.3-1.0-1.0-1.11.50.31.7-1.61.61.3
Patch foraging time to switch 0 sec0.10.10.3-0.5-0.5-0.5-0.60.5-0.10.00.10.3-0.5
Patch foraging water rate 0 sec0.40.92.80.81.11.11.2-0.8-0.8-0.4-0.1-0.11.7
Patch foraging water rate 12 sec0.20.51.20.90.90.91.1-0.7-0.0-0.50.5-0.2-0.3
Patch foraging water rate 18 sec0.20.30.80.90.70.60.7-0.8-0.5-0.20.1-0.30.4
Patch foraging water rate 24 sec2.63.65.02.22.22.22.1-1.9-2.0-1.91.8-1.40.7
Patch foraging water rate 6 sec0.40.61.41.20.70.80.9-1.1-0.1-0.90.5-0.80.5
Seeking ratio, delayed vs. immediate footshock0.30.41.1-0.5-0.5-0.6-0.60.41.10.3-0.3-0.6-0.6
Distance traveled before self-admin1.72.25.1-2.3-1.4-1.4-1.52.01.21.6-1.41.10.1
Distance traveled after self-admin0.80.93.6-0.6-0.6-0.5-0.50.7-0.70.6-1.21.21.9
Extensor digitorum longus weight0.41.53.4-1.0-1.2-1.2-1.21.01.81.1-1.40.5-1.4
Bone: elastic displacement0.40.50.80.70.90.80.8-0.7-0.7-0.60.3-0.8-0.1
Bone: elastic work0.60.73.40.60.90.80.8-0.5-1.8-0.30.50.20.8
Bone: endosteal estimation0.30.73.50.50.80.80.8-0.3-1.9-0.70.50.10.9
Bone: endosteal perimeter0.51.13.41.01.00.91.0-0.9-1.9-1.01.2-0.20.3
Epididymis fat weight2.79.112.33.33.43.53.5-3.0-3.3-3.23.3-1.40.4
Delta time in closed arm before/after self-admin0.90.82.1-0.9-0.8-0.7-0.70.80.41.3-0.81.40.7
Delta time in open arm before/after self-admin0.10.10.3-0.1-0.2-0.3-0.30.20.0-0.1-0.5-0.6-0.4
Diff in mean of infusions in LGA sessions0.10.10.50.20.0-0.1-0.00.0-0.70.0-0.10.20.5
Delay discount exponential model param4.65.27.52.52.62.72.7-2.3-1.8-2.52.5-1.60.1
Extinction: sum of active levers before priming1.31.42.7-1.2-1.6-1.6-1.41.00.21.3-1.10.9-0.7
Active lever presses in extinction session 60.10.10.3-0.1-0.2-0.3-0.20.5-0.10.2-0.2-0.5-0.4
Bone: final force0.30.51.7-0.4-0.3-0.2-0.20.5-0.90.6-0.21.31.1
Bone: final moment0.30.51.6-0.3-0.1-0.1-0.00.4-1.10.6-0.21.21.3
Food consumed during 24 hour testing period0.20.31.10.1-0.4-0.3-0.2-0.1-1.00.30.41.00.5
Glucose0.40.62.70.4-0.00.10.1-0.5-1.0-0.60.31.11.6
Heart weight2.03.29.51.81.91.81.6-1.8-3.1-1.71.6-0.50.9
Delay discount hyperbolic model param4.95.57.72.52.72.82.7-2.4-1.9-2.62.6-1.70.4
Intermittent access intake day 1-15 change0.00.10.20.20.10.20.2-0.20.2-0.4-0.2-0.1-0.5
Intermittent access intake escalation0.00.10.40.20.10.10.1-0.20.4-0.4-0.3-0.4-0.6
Intermittent access intake escalation 20.10.10.10.30.20.30.2-0.10.3-0.4-0.1-0.2-0.3
Intermitt. access day 1 inactive lever presses0.20.84.3-0.3-0.1-0.2-0.2-0.0-1.4-0.10.41.22.1
Intermitt. access day 15 inactive lever presses0.40.91.8-1.1-0.8-1.0-0.90.90.30.8-0.81.11.3
Intermitt. access escalation Index0.20.21.1-0.4-0.5-0.3-0.30.00.60.20.3-0.0-1.1
Intermittent access day 1 total infusions2.94.77.7-2.5-2.5-2.4-2.32.30.82.3-1.82.80.7
Intermittent access day 15 total infusions1.92.93.9-2.0-1.9-1.8-1.91.81.31.7-2.01.6-0.1
Intermittent access terminal intake (last 3 days)2.22.94.2-2.1-1.9-1.8-1.91.91.31.8-1.81.6-0.1
Intermittent access total infusions5.46.49.0-3.0-2.8-2.7-2.82.81.22.8-2.43.00.6
Intermittent access day 1 locomotion2.43.05.5-2.0-1.9-1.8-1.81.90.71.9-1.52.41.0
Intermittent access day 15 total locomotion0.81.44.4-1.2-1.2-1.2-1.11.10.21.0-0.82.11.1
Intermittent access total locomotion1.41.76.0-1.2-1.2-1.0-1.01.1-0.21.1-0.62.41.8
Intermittent access standard deviation1.02.05.9-1.1-1.2-1.0-1.11.4-0.91.1-1.22.42.0
Left kidney weight3.817.542.64.34.54.44.3-4.5-6.5-3.84.0-1.71.0
Right kidney weight5.324.258.85.25.15.15.0-5.2-7.7-4.84.5-1.72.2
Cocaine induced anxiety0.50.71.10.90.91.01.0-0.8-0.6-0.91.0-0.1-0.3
Post-drug Anxiety1.71.83.21.51.71.81.6-1.5-0.4-1.41.3-1.2-0.1
Baseline Anxiety0.30.31.1-0.5-0.3-0.2-0.40.61.10.7-0.8-0.30.2
Tail length0.52.13.41.81.71.71.4-1.8-1.2-1.60.8-1.21.0
Length with tail1.87.810.73.33.33.23.0-3.2-3.1-2.91.8-1.91.3
Length without tail2.16.715.52.72.92.82.8-2.7-3.9-2.31.9-0.91.7
Times rat made contact with spout0.40.41.8-0.2-0.5-0.4-0.30.10.10.7-0.71.11.3
Lifetime Intake6.07.311.6-3.1-3.0-2.9-2.93.01.03.0-2.43.40.9
Liver weight, left0.81.42.71.21.21.31.3-1.0-0.4-1.21.7-1.3-0.7
Liver weight, right6.110.617.83.83.23.43.2-3.7-2.3-3.74.2-3.0-0.5
Locomotor activity1.42.23.61.81.61.71.8-1.6-1.9-1.41.4-0.70.1
Locomotor testing distance0.00.10.20.40.20.40.5-0.3-0.1-0.20.2-0.00.2
Locomotor testing rearing0.30.61.20.90.70.90.8-0.7-1.1-0.61.10.10.4
Locomotion in novel chamber0.60.73.40.1-0.2-0.1-0.1-0.11.6-0.3-0.1-1.1-1.8
Locomotion in novel chamber post-restriction1.11.73.6-1.2-1.5-1.5-1.51.11.90.9-0.90.5-1.5
Fecal boli incidents, locomotor time 11.21.85.0-1.2-1.2-1.2-1.21.20.21.3-1.01.62.2
Change in fecal boli incidents, locomotor task2.02.03.51.61.61.71.9-1.4-0.8-1.31.2-1.2-0.9
Time >=10cm from walls, locomotor time 10.40.41.40.70.50.50.6-0.5-1.2-0.40.3-0.11.0
Bouts of movement, locomotor time 10.40.40.90.70.30.30.5-0.6-0.8-0.50.9-0.90.5
Total resting periods, locomotor time 10.10.20.50.30.10.00.2-0.1-0.6-0.10.5-0.60.7
Rest time, locomotor task time 10.30.41.70.20.00.1-0.10.1-0.9-0.10.70.81.3
Distance moved, locomotor task time 10.81.22.00.91.41.31.4-1.0-0.3-1.00.5-1.1-1.4
Vertical activity count, locomotor time 10.51.32.31.21.41.51.5-1.3-1.0-1.20.6-0.60.6
Time >=10cm from walls, locomotor time 20.30.40.90.80.50.50.4-0.6-0.9-0.70.5-0.80.9
Bouts of movement, locomotor time 20.50.82.8-0.7-0.9-0.9-0.80.71.00.30.70.2-1.7
Total resting periods, locomotor time 20.71.22.2-1.1-1.3-1.3-1.21.01.10.80.20.8-1.5
Rest time, locomotor task time 20.60.83.5-0.7-0.9-0.7-0.90.80.20.8-0.61.90.8
Distance moved, locomotor task time 21.01.21.71.21.31.11.3-1.2-0.9-1.20.8-1.3-0.2
Vertical activity count, locomotor time 20.81.11.61.20.90.91.0-1.2-1.3-1.20.9-0.01.0
Light reinforcement 10.00.10.3-0.2-0.1-0.2-0.10.30.30.5-0.50.20.3
Light reinforcement 20.50.71.90.80.50.60.7-0.6-0.3-0.91.4-1.1-0.9
Bone: marrow area0.40.83.70.50.90.80.8-0.3-1.9-0.70.50.11.0
Bone: maximum diameter0.61.25.21.01.00.91.0-0.8-2.3-0.61.00.60.8
Bone: maximum force0.50.93.5-0.5-0.4-0.3-0.30.6-1.30.8-0.31.91.5
Bone: maximum moment0.50.93.1-0.3-0.2-0.2-0.10.5-1.50.7-0.31.81.5
Mean time between licks in bursts0.41.02.8-0.9-0.6-0.7-0.70.91.21.0-1.0-0.9-1.7
Mean num. licks in bursts0.61.01.81.11.01.01.1-1.1-1.3-0.90.90.10.9
Cd content in liver0.40.50.90.80.80.91.0-0.8-0.4-0.50.0-0.1-0.7
Co content in liver0.70.91.6-1.2-0.8-0.9-0.51.20.81.2-1.30.80.2
Cu content in liver3.34.07.9-2.1-2.0-2.1-2.22.02.81.7-2.51.1-0.4
Fe content in liver2.73.38.21.82.01.91.8-1.8-2.9-1.91.2-1.50.2
K content in liver0.10.10.3-0.4-0.3-0.3-0.30.40.50.2-0.5-0.30.4
Mg content in liver0.20.20.5-0.5-0.4-0.4-0.40.50.30.2-0.60.70.7
Mn content in liver0.20.20.5-0.2-0.7-0.5-0.40.30.70.20.40.2-0.3
Na content in liver0.10.10.3-0.00.00.00.10.10.2-0.4-0.40.50.6
Rb content in liver0.60.71.4-1.2-0.6-0.7-0.71.10.51.1-1.20.50.4
Se content in liver0.40.52.40.90.30.40.2-0.80.5-0.7-0.1-0.1-1.5
Sr content in liver2.11.86.4-1.2-1.4-1.3-1.11.22.50.9-1.11.1-0.6
Zn content in liver0.10.10.40.10.20.20.2-0.10.2-0.1-0.6-0.10.1
Bone: minimum diameter0.20.31.0-0.1-0.1-0.1-0.10.3-1.00.10.41.00.8
Time in familiar zone, hab. session 10.30.30.5-0.6-0.5-0.5-0.50.70.30.7-0.60.40.2
Time in novel zone, hab. session 11.51.52.21.41.31.31.5-1.5-1.3-1.31.2-0.8-0.4
Total zone transitions, hab. session 11.11.55.0-0.7-0.9-0.9-1.00.62.20.9-1.7-0.8-1.5
Total locomotion distance, hab. session 10.20.41.30.20.10.1-0.1-0.31.2-0.1-0.5-0.9-1.0
Locomotion velocity, hab. session 10.30.52.1-0.3-0.4-0.4-0.70.21.40.3-1.0-0.5-0.6
Time in familiar zone, hab. session 20.30.40.90.40.30.40.6-0.30.8-0.50.5-0.9-0.8
Time in novel zone, hab. session 20.50.51.8-0.3-0.4-0.4-0.50.3-0.90.5-0.61.30.9
Total zone transitions, hab. session 21.72.25.6-1.5-1.4-1.5-1.41.61.31.6-2.41.20.6
Total locomotion distance, hab. session 21.41.93.3-1.5-1.3-1.4-1.51.50.91.5-1.81.30.6
Locomotion velocity, hab. session 21.82.54.5-1.7-1.5-1.6-1.71.71.11.7-2.11.30.8
Novel to familiar place preference ratio3.33.65.32.22.22.22.3-2.3-1.7-2.01.1-1.6-0.9
Novelty place preference4.44.76.92.52.52.52.5-2.6-1.9-2.31.4-1.9-1.1
Time in novel zone, NPP test5.25.57.92.72.62.72.7-2.8-2.1-2.51.5-2.0-1.2
Total zone transitions, NPP test1.52.25.9-1.4-1.3-1.4-1.31.32.11.5-2.40.3-0.6
Total locomotion distance, NPP test0.81.02.9-1.1-0.8-0.9-0.81.11.11.2-1.70.30.2
Locomotion velocity, NPP test1.21.73.1-1.4-1.2-1.3-1.21.51.71.6-1.80.40.0
Intraocular pressure0.30.40.60.70.70.70.7-0.5-0.7-0.60.5-0.2-0.4
Delta distance traveled before/after self-admin2.02.24.62.11.11.21.4-1.7-2.1-1.30.7-0.31.7
Delta ambulatory time before/after self-admin1.31.64.31.70.90.91.2-1.3-2.1-0.90.2-0.11.8
Parametrial fat weight1.22.84.72.11.71.81.6-1.9-1.0-1.82.2-1.70.3
Pavlov. Cond. lever latency0.10.20.50.30.60.50.7-0.2-0.2-0.20.1-0.5-0.1
Pavlov. Cond. magazine entry latency1.82.43.9-1.7-2.0-1.9-1.81.61.21.6-1.31.4-0.2
Pavlov. Cond. change in total contacts3.74.05.9-2.2-2.4-2.4-2.42.11.52.1-1.71.90.3
Pavlov. Cond. index score1.01.32.1-1.2-1.4-1.4-1.41.10.51.1-0.81.40.5
Pavlov. Cond. latency score0.50.71.3-0.8-1.1-1.0-1.00.70.30.7-0.51.10.3
Pavlov. Cond. lever contacts0.80.91.8-1.0-1.3-1.2-1.30.90.70.8-0.61.00.5
Pavlov. Cond. magazine entry number2.22.73.91.82.01.91.8-1.8-1.5-1.81.4-1.4-0.1
Pavlov. Cond. intertrial magazine entries0.20.31.3-0.10.1-0.0-0.10.10.10.3-1.10.11.1
Pavlov. Cond. lever-magazine prob. diff.1.01.32.1-1.2-1.5-1.4-1.41.10.81.1-0.81.20.3
Pavlov. Cond. response bias1.92.33.5-1.7-1.9-1.8-1.81.61.21.5-1.21.50.3
Pavlov. Cond. lever latency0.10.11.00.20.00.10.1-0.30.20.10.2-0.2-1.0
Pavlov. Cond. magazine entry latency1.92.34.1-1.6-1.4-1.5-1.51.60.71.7-2.01.61.3
Pavlov. Cond. change in total contacts0.61.05.3-0.20.30.10.10.1-1.80.2-0.51.12.3
Pavlov. Cond. index score0.60.82.3-0.8-0.6-0.7-0.70.8-0.00.8-1.10.91.5
Pavlov. Cond. latency score0.81.02.8-1.0-0.7-0.8-0.91.00.11.0-1.41.01.7
Pavlov. Cond. lever contacts0.10.11.0-0.10.10.00.00.2-0.2-0.2-0.20.11.0
Pavlov. Cond. magazine entry number0.40.51.20.70.40.50.5-0.7-0.0-0.81.1-0.6-1.0
Pavlov. Cond. intertrial magazine entries0.10.20.8-0.3-0.4-0.3-0.30.3-0.2-0.00.60.60.9
Pavlov. Cond. lever-magazine prob. diff.0.50.61.8-0.8-0.5-0.6-0.60.8-0.00.7-1.00.81.3
Pavlov. Cond. response bias0.40.51.3-0.7-0.5-0.6-0.60.8-0.00.5-0.70.81.2
Time in closed arm before self-admin0.40.51.0-0.5-0.8-1.0-0.80.90.80.6-0.70.70.3
Time in closed arm after self-admin0.30.31.70.10.1-0.10.10.0-0.40.30.40.91.3
Time in open arm before self-admin0.20.20.50.40.50.70.5-0.50.1-0.40.6-0.00.3
Time in open arm after self-admin0.30.30.90.20.20.50.3-0.30.5-0.40.1-1.0-0.9
Bone: periosteal estimation0.30.52.90.30.50.50.5-0.1-1.7-0.30.50.70.9
Bone: periosteal perimeter1.01.75.71.31.31.31.3-1.1-2.4-1.01.40.20.7
Bone: post-yield work0.91.33.6-1.1-1.0-1.0-1.01.20.11.2-1.41.90.5
Progressive ratio test 1 active lever presses4.04.96.6-2.6-2.5-2.4-2.42.50.72.5-2.22.50.6
Progressive ratio test 1 breakpoint3.84.66.3-2.5-2.4-2.4-2.32.50.82.5-2.22.30.5
Progressive ratio test 1 inactive lever presses4.15.99.4-3.0-2.6-2.8-2.62.60.72.6-2.03.10.9
Progressive ratio test 2 active lever presses4.24.97.8-2.7-2.6-2.4-2.52.31.12.3-1.72.80.8
Progressive ratio test 2 breakpoint4.75.47.8-2.8-2.7-2.6-2.62.41.22.5-1.92.70.6
Progressive ratio test 2 inactive lever presses3.04.97.3-2.7-2.6-2.6-2.52.31.82.1-1.72.30.4
Incentive Sensitization - Responses0.60.81.4-1.1-1.2-1.1-1.10.70.80.8-0.31.00.2
Incentive Sensitization - Breakpoint0.60.81.5-1.1-1.2-1.1-1.20.70.70.8-0.21.10.2
Sum of active levers in priming session hrs 5-60.00.00.10.20.10.10.2-0.2-0.2-0.3-0.1-0.1-0.3
Progressive ratio0.10.10.5-0.10.1-0.0-0.20.1-0.40.2-0.50.30.7
Food seeking constrained by brief footshock0.20.20.8-0.5-0.1-0.2-0.30.50.00.6-0.40.9-0.5
Seeking ratio, punishment vs. effort0.10.20.5-0.4-0.4-0.3-0.20.40.20.40.10.7-0.5
Retroperitoneal fat weight3.012.718.94.03.73.83.8-3.9-4.3-3.54.3-1.80.3
Reaction time number correct0.40.72.90.0-0.5-0.4-0.5-0.21.3-0.20.8-1.1-1.7
Reaction time mean minus median0.00.00.20.1-0.1-0.1-0.1-0.2-0.4-0.4-0.3-0.00.0
Reaction time mean minus median AUC0.20.50.90.80.60.60.7-0.8-0.8-1.00.7-0.3-0.0
Reaction time num false alarms0.30.40.60.80.60.70.8-0.8-0.7-0.40.3-0.2-0.8
Reaction time num false alarms AUC0.30.41.00.70.70.80.9-0.7-0.5-0.30.2-0.4-1.0
Reaction time trials correct on left0.40.72.90.0-0.5-0.4-0.5-0.21.3-0.20.8-1.1-1.7
Reaction time trials on left0.40.73.0-0.0-0.6-0.4-0.6-0.21.4-0.20.7-1.0-1.7
Reaction time mean0.10.20.60.30.50.40.4-0.3-0.5-0.8-0.0-0.40.3
Reaction time mean AUC0.10.10.50.20.40.30.3-0.3-0.4-0.7-0.1-0.40.2
Median of all reaction times0.10.10.40.10.50.40.3-0.1-0.3-0.7-0.2-0.50.2
Reaction time omissions1.21.73.3-1.2-1.8-1.7-1.61.21.41.1-1.00.7-1.1
Reaction time false alarm rate0.30.41.00.60.80.91.0-0.5-0.9-0.3-0.0-0.1-0.3
Reaction time premature initiation rate0.50.73.5-0.2-0.5-0.5-0.40.2-1.00.4-0.31.91.2
Reaction time premature initiations0.20.31.4-0.1-0.6-0.5-0.5-0.0-0.50.10.21.20.4
Std. dev. reaction times0.30.61.40.80.60.60.6-1.0-1.2-1.10.5-0.30.2
Reaction time trials completed0.40.73.0-0.0-0.6-0.4-0.6-0.21.4-0.20.7-1.0-1.7
Reaction time trials AUC0.30.62.60.2-0.3-0.2-0.3-0.31.0-0.30.9-1.0-1.6
Run reversals in cocaine runway, females0.90.91.51.11.20.90.9-1.2-0.3-1.01.1-1.1-0.5
Run reversals in cocaine runway, males0.20.20.7-0.00.40.30.20.2-0.10.3-0.9-0.60.2
Latency to leave start box in cocaine runway0.50.51.80.50.30.40.3-0.7-0.5-0.60.7-1.3-1.2
Latency to leave start box in cocaine runway, F0.20.20.8-0.5-0.2-0.2-0.30.30.20.3-0.6-0.8-0.9
Latency to leave start box in cocaine runway, M1.91.84.11.60.91.11.0-1.6-1.1-1.52.0-1.3-0.8
Std. dev. time between licks in bursts0.20.31.0-0.70.0-0.2-0.20.60.30.8-1.0-0.60.5
Total sessions with >9 infusions2.02.55.5-1.7-1.7-1.5-1.61.7-0.61.7-1.02.31.0
Short access day 1 total inactive lever presses1.92.57.5-1.3-0.7-0.9-0.91.5-1.01.4-2.02.02.7
Short access day 10 total inactive lever presses0.71.74.30.91.21.11.1-1.2-1.6-1.21.4-0.12.1
Short access day 1 total infusions1.31.73.2-1.4-1.2-1.2-1.21.4-0.51.1-1.01.61.8
Short access day 10 total infusions1.41.84.5-1.6-1.4-1.4-1.41.5-0.31.5-0.82.10.5
Short access total infusions3.44.38.3-2.4-2.2-2.2-2.22.3-0.12.2-1.62.91.1
Short access day 1 locomotion0.60.71.6-0.9-0.7-0.7-0.60.9-0.70.6-0.71.01.3
Short access day 10 total locomotion1.01.86.0-1.2-1.3-1.2-1.10.9-0.50.8-0.42.22.5
Short access total locomotion1.21.54.0-1.2-1.2-1.1-1.01.2-0.71.0-0.62.01.5
One hour access (0.3 mA shock)7.78.811.9-3.3-3.5-3.2-3.33.32.83.1-2.72.8-0.3
Compulsive drug intake0.40.41.0-0.5-0.9-0.8-1.00.31.00.6-0.50.20.2
One hour access (shock baseline)1.72.63.9-2.0-1.7-1.6-1.71.91.31.7-1.51.7-0.6
Social response proportion0.20.20.80.2-0.4-0.4-0.4-0.2-0.60.2-0.3-0.1-0.9
Social responses0.60.81.9-0.6-0.9-0.9-0.90.90.51.3-1.40.7-0.3
Social time3.04.16.2-2.0-2.3-2.2-2.12.21.82.1-2.51.90.5
Soleus weight0.61.75.6-0.9-1.0-0.9-0.60.90.11.1-0.92.32.4
Bone: stiffness0.40.62.60.00.00.10.10.1-1.40.20.21.21.6
Tibialis anterior weight1.86.28.4-2.7-2.7-2.6-2.52.82.92.7-2.72.0-0.6
Time to tail flick, vehicle, before self-admin0.10.10.30.1-0.2-0.2-0.2-0.2-0.50.0-0.10.60.1
Time to tail flick, vehicle, after self-admin0.60.81.31.10.90.71.1-0.8-0.9-0.80.1-1.10.7
Time to tail flick, test, before self-admin0.40.41.4-0.5-0.5-0.5-0.40.40.80.70.40.5-1.2
Time to tail flick, test, after self-admin0.10.10.5-0.1-0.1-0.10.10.10.4-0.10.3-0.7-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.10.1-0.10.20.3-0.30.2-0.5-0.60.6
Delta time to tail flick, test, before/after SA0.30.31.80.20.20.30.3-0.00.5-0.6-0.4-1.3-0.0
Tibia length0.10.42.20.40.40.40.4-0.5-1.5-0.3-0.10.50.4
Ambulatory time before self-admin1.01.43.5-1.9-1.1-1.0-1.21.61.11.2-1.20.8-0.1
Ambulatory time after self-admin0.50.52.4-0.4-0.4-0.2-0.30.5-0.40.4-1.60.41.4
Bone: tissue strength0.50.50.70.80.70.80.8-0.8-0.8-0.60.5-0.40.1
Total heroin consumption1.31.52.3-1.1-1.5-1.5-1.31.30.61.5-1.31.2-0.1
Bone: trabecular number0.20.30.70.60.60.60.6-0.6-0.0-0.60.5-0.9-0.3
Bone: trabecular spacing0.40.52.0-0.5-0.4-0.4-0.30.6-0.80.5-0.21.41.2
Bone: trabecular thickness0.20.20.80.30.20.20.2-0.30.5-0.70.8-0.9-0.1
Bone: trabecular tissue density0.10.20.40.40.50.40.4-0.30.3-0.2-0.4-0.60.0
Water consumed over 24 hours0.30.42.30.0-0.3-0.2-0.20.1-0.40.7-0.61.01.5
Number of responses in last shaping day6.36.910.5-3.2-3.1-3.0-3.02.81.12.7-2.42.90.6