Hub : Genes

Ddit4l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Ddit4l 0.38 0.13 3.2e-06 0.14 0.15 0.17 0.17 3.1e-04 2.2e-04 6.8e-05 6.6e-05
2 IC gene expression Ddit4l 0.21 0.07 1.7e-09 0.16 0.22 0.23 0.21 4.0e-07 1.9e-09 6.0e-10 3.1e-09
3 BLA gene expression Ddit4l 0.07 0.04 6.5e-03 -0 0.01 0 -0 4.7e-01 1.1e-01 1.6e-01 4.0e-01
4 LHb gene expression Ddit4l 0.19 0.1 1.2e-03 0.08 0.12 0.05 0.08 6.3e-03 1.2e-03 2.1e-02 6.0e-03
5 PL gene expression Ddit4l 0.04 0.03 2.4e-03 0.02 0.02 0.02 0.02 3.5e-03 2.9e-03 4.4e-03 2.9e-03
6 NAcc gene expression Ddit4l 0.12 0.05 5.6e-17 0.09 0.11 0.11 0.12 1.3e-13 5.9e-16 7.2e-17 5.4e-17
7 pVTA gene expression Ddit4l 0.16 0.07 2.2e-07 0.11 0.09 0.11 0.1 2.7e-09 1.3e-07 7.1e-09 1.2e-08
8 Brain gene expression Ddit4l 0.18 0.06 2.4e-13 0.14 0.16 0.16 0.16 1.2e-12 7.2e-15 1.8e-14 1.8e-14
9 Adipose gene expression Ddit4l 0.04 0.03 2.4e-03 0.02 0.02 0.02 0.02 6.4e-03 2.0e-03 2.1e-03 2.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.42.53.9-0.61.81.0-1.8-1.7-1.82.0-1.8-1.3
Area under the delay curve0.00.10.3-0.5-0.3-0.30.1-0.2-0.30.0-0.2-0.0
BMI with tail1.86.317.04.1-3.0-1.62.32.72.6-2.41.60.6
BMI without tail1.05.416.54.1-2.7-1.51.62.62.5-1.91.70.1
Body weight1.77.426.45.1-2.9-2.22.62.72.6-2.21.40.2
Weight adjusted by age0.10.20.70.1-0.4-0.30.50.70.7-0.80.3-0.4
Bone surface0.20.41.10.50.51.0-1.0-0.3-0.40.4-0.6-0.4
Bone volume0.30.61.70.40.81.0-1.3-0.5-0.60.7-0.7-0.7
Breakpoint value in progressive ratio session0.71.22.9-0.10.6-1.0-0.1-1.6-1.31.7-1.3-1.0
Number of licking bursts0.30.93.81.3-0.7-1.11.90.60.5-0.60.00.4
Context. condit. distance diff. score0.30.40.9-0.60.6-0.30.3-0.8-1.00.5-0.70.1
Locomotion velocity, session 11.72.03.40.9-1.2-1.81.81.01.6-1.81.1-0.6
Locomotion distance, session 12.63.38.70.8-1.8-3.02.80.91.5-2.11.2-0.4
Locomotion velocity, session 20.30.30.8-0.3-0.2-0.90.7-0.20.3-0.6-0.2-0.9
Locomotion distance, session 22.53.59.3-0.0-2.0-3.12.80.81.5-2.21.4-0.4
Locomotion velocity, session 32.32.74.61.5-1.4-1.62.21.71.6-1.91.70.7
Locomotion distance, session 30.60.71.40.7-0.7-0.31.20.90.7-1.10.70.9
Stereotopy head waving bouts, day 30.50.61.20.6-0.4-0.50.71.01.0-0.71.10.6
Stereotopy head waving duration, day 31.01.32.11.5-1.0-0.91.21.31.3-0.91.20.5
Locomotion velocity, session 70.80.93.20.8-1.1-1.81.50.20.4-0.70.1-0.5
Locomotion distance, session 71.62.05.21.4-1.8-1.92.30.90.9-1.50.50.3
Stereotopy head waving bouts, day 70.30.30.9-0.50.70.7-0.60.40.5-0.11.00.1
Stereotopy head waving duration, day 70.40.51.9-0.50.30.4-0.30.70.9-0.71.40.4
Locomotion velocity, session 80.30.41.3-0.0-0.3-1.21.00.20.4-0.80.3-0.4
Locomotion distance, session 81.92.711.70.0-1.4-3.42.90.00.4-1.30.4-0.6
Degree of sensitization distance0.30.41.20.3-0.6-1.10.6-0.5-0.30.1-0.6-0.8
Degree of sensitization stereotypy0.40.51.7-0.71.00.8-1.3-0.2-0.00.50.5-0.3
Conditioned locomotion0.91.03.3-1.21.31.0-1.8-0.2-0.10.60.1-1.2
Cocaine response after cond. corrected0.81.21.9-0.61.30.4-1.2-1.3-1.11.4-0.8-1.1
Cocaine response after cond. not corrected1.42.13.2-1.01.60.5-1.6-1.8-1.51.4-1.3-1.7
Cocaine response before conditioning0.20.21.00.1-0.5-0.40.30.30.5-1.00.2-0.3
Saline control response3.04.27.30.9-2.3-0.21.52.32.7-2.72.41.9
Bone: connectivity density1.52.43.6-1.21.91.0-1.4-1.7-1.81.7-1.9-1.1
Bone: cortical apparent density0.20.41.0-0.20.3-0.4-0.0-1.0-0.81.0-0.7-0.1
Bone: cortical area1.22.010.23.2-1.30.50.31.61.3-0.70.60.8
Bone: cortical porosity0.91.01.60.8-0.9-1.00.81.21.1-1.31.0-0.2
Bone: cortical porosity1.21.32.01.2-1.3-1.41.01.31.2-1.31.1-0.3
Bone: cortical thickness0.50.86.12.5-0.2-0.2-0.30.3-0.10.7-0.4-0.5
Bone: cortical thickness0.40.52.50.90.2-0.4-0.7-0.1-0.20.6-0.6-1.6
Bone: cortical tissue density0.20.30.9-0.20.2-0.50.1-0.9-0.80.9-0.60.0
Condit. Reinf. active minus inactive responses2.12.45.71.2-1.9-2.22.40.91.3-1.41.10.7
Condit. Reinf. active-inactive response ratio2.93.17.52.0-2.3-2.62.70.71.0-1.10.70.8
Condit. Reinf. active responses0.91.12.40.2-1.4-1.41.60.51.0-1.11.00.4
Condit. Reinf. inactive responses0.50.61.5-1.20.81.2-1.2-0.00.20.20.4-0.2
Incentive salience index mean1.21.63.31.2-1.5-1.51.80.91.2-1.11.00.5
Condit. Reinf. lever presses0.30.51.00.6-0.30.20.41.01.0-0.70.90.5
Condit. Reinf. active minus inactive responses0.50.83.21.10.61.8-0.70.50.40.40.11.0
Condit. Reinf. active-inactive response ratio0.40.61.70.61.01.1-0.5-0.3-0.61.3-0.60.6
Condit. Reinf. active responses0.50.72.71.6-0.11.1-0.30.90.9-0.20.30.6
Condit. Reinf. inactive responses1.42.13.61.9-1.7-0.51.01.71.8-1.81.20.3
Condit. Reinf. lever presses0.30.52.21.50.31.2-0.40.40.30.3-0.40.1
Condit. Reinf. lever reinforcers received0.30.51.81.40.11.1-0.50.60.60.1-0.00.3
Conditioned reinforcement - actives0.31.33.80.1-0.50.31.01.11.2-0.81.82.0
Conditioned reinforcement - inactives0.20.51.3-1.20.51.0-0.7-0.5-0.30.60.30.9
Conditioned locomotion0.40.62.7-0.30.71.7-0.70.60.1-0.10.50.8
Patch foraging indifference point 0 sec0.10.21.1-0.50.10.60.30.0-0.1-0.4-0.01.0
Patch foraging indifference point AUC0.30.73.71.9-0.70.50.41.00.6-0.40.00.7
Delay disc. indifference point, 0s delay0.91.04.5-0.20.42.1-0.50.70.1-0.20.31.8
Delay disc. indifference point, 16s delay0.50.61.40.7-1.2-1.01.20.70.6-0.70.30.1
Delay disc. indifference point, 2s delay0.70.83.2-1.10.81.8-1.10.1-0.30.10.30.7
Delay disc. indifference point, 24s delay0.30.52.2-1.50.30.2-0.9-0.5-0.50.3-0.3-0.4
Delay disc. indifference point, 4s delay0.50.51.1-1.00.30.0-0.4-1.0-0.80.7-1.0-0.6
Delay disc. indifference point, 8s delay0.50.82.8-0.1-1.1-1.71.10.40.5-1.00.8-0.2
Indifference point function ln k0.41.23.9-0.1-1.0-2.01.70.40.6-1.20.8-0.0
Indifference point function log k0.41.23.9-0.1-1.0-2.01.70.40.6-1.20.8-0.0
Patch foraging total patch changes 0 sec0.10.21.1-0.2-0.10.40.60.30.2-0.60.11.0
Patch foraging total patch changes 12 sec0.10.20.60.5-0.30.60.20.10.00.0-0.40.8
Patch foraging total patch changes 18 sec0.10.31.10.2-0.40.60.70.30.1-0.4-0.21.0
Patch foraging total patch changes 24 sec0.41.32.41.0-0.70.41.11.51.2-1.11.11.5
Patch foraging total patch changes 6 sec0.20.40.90.90.20.90.1-0.0-0.50.3-0.90.8
Patch foraging time to switch 0 sec0.52.14.7-2.21.81.0-1.5-1.7-1.41.6-0.5-0.2
Patch foraging water rate 0 sec0.20.92.91.7-0.7-0.81.01.10.8-0.8-0.0-0.8
Patch foraging water rate 12 sec0.52.13.31.7-1.8-1.81.81.41.3-1.21.00.1
Patch foraging water rate 18 sec0.20.52.11.4-0.3-0.71.00.70.4-0.2-0.3-0.4
Patch foraging water rate 24 sec1.31.95.01.6-1.4-2.02.21.11.0-1.10.4-0.1
Patch foraging water rate 6 sec2.74.016.42.1-2.2-4.02.80.60.7-0.70.1-1.3
Seeking ratio, delayed vs. immediate footshock1.92.85.2-2.32.21.3-2.1-1.5-1.61.0-1.2-1.3
Distance traveled before self-admin0.40.82.20.00.41.1-0.31.51.2-0.81.10.6
Distance traveled after self-admin0.10.21.2-0.20.10.70.10.40.3-0.20.41.1
Extensor digitorum longus weight2.18.426.65.2-3.1-2.11.73.43.2-1.92.50.0
Bone: elastic displacement0.70.82.01.4-0.9-0.80.61.21.0-0.70.9-0.1
Bone: elastic work0.70.93.92.0-0.9-1.40.60.50.4-0.10.2-1.0
Bone: endosteal estimation1.02.53.71.6-1.61.10.81.91.9-1.91.31.8
Bone: endosteal perimeter1.53.66.11.9-1.80.71.12.52.3-2.11.92.1
Epididymis fat weight1.26.19.33.0-2.5-0.22.33.02.7-3.02.02.2
Delta time in closed arm before/after self-admin0.80.71.20.3-1.0-0.61.10.60.9-1.00.80.9
Delta time in open arm before/after self-admin1.31.64.3-0.0-1.00.20.51.31.3-1.42.11.9
Diff in mean of infusions in LGA sessions1.93.47.1-1.41.6-0.3-0.7-2.7-2.42.4-2.4-1.1
Delay discount exponential model param0.10.20.70.80.10.40.10.60.5-0.20.40.3
Extinction: sum of active levers before priming0.91.42.4-0.30.7-0.7-0.7-1.4-1.31.5-1.5-1.5
Active lever presses in extinction session 60.90.91.9-1.30.80.1-0.3-1.4-1.31.1-1.2-0.1
Bone: final force0.30.41.31.2-0.80.10.60.60.6-0.30.20.7
Bone: final moment0.20.31.41.2-0.70.10.40.50.5-0.2-0.00.4
Food consumed during 24 hour testing period0.51.02.81.4-1.2-1.71.10.10.3-0.4-0.3-1.0
Glucose0.91.44.32.1-1.6-1.51.20.70.8-0.90.0-0.4
Heart weight1.62.67.12.7-1.9-0.81.01.81.9-1.71.20.2
Delay discount hyperbolic model param0.10.20.80.9-0.00.00.20.60.5-0.30.40.1
Intermittent access intake day 1-15 change0.10.41.6-0.91.01.3-0.6-0.3-0.20.1-0.00.4
Intermittent access intake escalation0.10.82.5-1.11.31.6-0.9-0.5-0.50.4-0.40.3
Intermittent access intake escalation 21.11.94.0-1.42.01.2-1.2-1.4-1.51.5-1.3-0.7
Intermitt. access day 1 inactive lever presses0.00.41.30.6-1.1-1.10.50.20.3-0.50.2-0.1
Intermitt. access day 15 inactive lever presses0.31.62.51.6-1.3-1.20.71.51.6-1.31.0-0.7
Intermitt. access escalation Index0.00.10.3-0.2-0.2-0.4-0.50.10.2-0.20.5-0.6
Intermittent access day 1 total infusions0.41.22.71.5-1.7-1.51.20.81.1-0.70.5-0.1
Intermittent access day 15 total infusions0.10.10.30.4-0.3-0.10.50.40.5-0.50.10.0
Intermittent access terminal intake (last 3 days)0.20.41.30.5-0.7-0.91.10.40.6-0.70.20.1
Intermittent access total infusions0.91.02.01.2-1.3-1.31.40.81.0-0.80.50.1
Intermittent access day 1 locomotion0.91.73.71.9-1.5-0.71.21.61.4-1.31.00.6
Intermittent access day 15 total locomotion0.20.82.40.60.21.5-0.01.30.7-0.80.71.2
Intermittent access total locomotion0.20.30.90.90.10.60.10.80.5-0.30.20.3
Intermittent access standard deviation0.00.20.90.5-0.10.80.20.40.3-0.10.10.9
Left kidney weight0.42.910.73.3-1.9-1.41.31.81.5-1.31.1-0.1
Right kidney weight0.53.49.73.1-2.1-1.61.52.11.8-1.61.2-0.1
Cocaine induced anxiety0.10.31.00.7-0.30.60.40.60.5-0.40.31.0
Post-drug Anxiety0.40.51.60.30.11.20.10.60.4-0.70.41.3
Baseline Anxiety0.10.10.4-0.30.2-0.3-0.2-0.6-0.40.3-0.2-0.3
Tail length0.00.31.91.40.00.1-0.30.40.30.20.3-0.1
Length with tail0.31.26.52.5-0.7-1.10.90.80.7-0.60.3-0.4
Length without tail0.21.03.41.8-0.8-0.41.30.90.7-1.00.30.5
Times rat made contact with spout3.33.78.3-0.81.5-1.1-0.7-2.4-2.12.2-2.3-2.9
Lifetime Intake1.11.42.61.2-1.6-1.51.60.91.2-0.90.70.2
Liver weight, left0.50.81.71.0-0.50.01.01.30.9-0.71.11.0
Liver weight, right0.20.32.00.5-0.10.60.50.40.10.10.21.4
Locomotor activity0.10.20.40.3-0.6-0.70.4-0.30.1-0.5-0.4-0.5
Locomotor testing distance0.30.62.00.7-1.1-1.40.7-0.20.4-0.7-0.2-0.9
Locomotor testing rearing0.51.94.00.3-0.4-2.00.6-1.8-1.00.7-1.9-2.0
Locomotion in novel chamber4.76.410.5-2.83.21.9-2.9-2.2-2.52.2-2.3-2.2
Locomotion in novel chamber post-restriction0.51.53.5-1.11.0-0.3-1.3-1.5-1.21.1-1.1-1.9
Fecal boli incidents, locomotor time 10.10.20.8-0.2-0.40.20.40.10.5-0.50.60.9
Change in fecal boli incidents, locomotor task0.50.52.20.3-0.4-1.50.30.1-0.10.2-0.3-1.4
Time >=10cm from walls, locomotor time 10.70.92.30.01.10.3-0.6-0.9-1.51.2-1.3-0.4
Bouts of movement, locomotor time 10.50.61.5-0.10.80.1-0.4-1.1-0.90.9-1.2-0.5
Total resting periods, locomotor time 10.20.20.60.20.4-0.20.1-0.7-0.50.4-0.8-0.3
Rest time, locomotor task time 10.10.20.5-0.20.60.6-0.7-0.3-0.00.60.20.2
Distance moved, locomotor task time 10.10.30.90.6-1.0-0.90.50.2-0.1-0.5-0.2-0.2
Vertical activity count, locomotor time 10.00.10.20.3-0.4-0.20.30.0-0.1-0.4-0.3-0.1
Time >=10cm from walls, locomotor time 21.03.04.51.7-1.8-1.51.72.11.9-1.91.90.5
Bouts of movement, locomotor time 20.20.52.1-0.90.51.4-0.9-0.5-0.40.1-0.20.8
Total resting periods, locomotor time 20.10.52.2-0.90.61.5-0.9-0.5-0.40.1-0.20.6
Rest time, locomotor task time 20.50.92.6-0.61.01.5-1.6-0.6-0.60.8-0.6-0.5
Distance moved, locomotor task time 20.30.51.00.1-1.0-0.81.00.40.4-0.70.60.5
Vertical activity count, locomotor time 20.00.10.1-0.2-0.1-0.30.30.00.2-0.40.3-0.1
Light reinforcement 11.14.97.92.8-2.4-2.12.62.32.4-2.31.50.2
Light reinforcement 20.10.20.80.8-0.2-0.50.20.30.1-0.0-0.1-0.9
Bone: marrow area0.92.33.31.5-1.61.10.81.81.8-1.81.21.8
Bone: maximum diameter1.12.26.02.4-1.51.00.51.81.6-1.40.91.5
Bone: maximum force0.51.03.11.7-1.2-0.11.00.91.0-0.90.50.9
Bone: maximum moment0.40.72.91.7-1.10.00.70.70.7-0.70.20.6
Mean time between licks in bursts0.00.21.20.5-0.5-0.00.70.1-0.1-0.3-0.11.1
Mean num. licks in bursts1.02.74.6-1.51.50.3-2.2-1.8-1.61.7-1.4-2.1
Cd content in liver0.30.42.10.60.00.50.4-0.2-0.20.4-0.21.5
Co content in liver6.07.19.52.6-3.1-2.13.02.73.0-2.82.61.6
Cu content in liver1.11.33.0-1.51.70.6-0.5-1.3-1.31.1-1.1-0.4
Fe content in liver1.11.35.7-0.60.92.4-1.20.70.6-0.10.91.3
K content in liver0.80.83.1-1.01.11.8-1.1-0.1-0.40.4-0.40.2
Mg content in liver0.10.10.6-0.80.60.40.1-0.1-0.2-0.1-0.30.1
Mn content in liver0.40.51.3-0.10.41.1-1.0-0.5-0.50.8-0.80.3
Na content in liver0.10.10.3-0.40.30.5-0.5-0.1-0.30.4-0.3-0.2
Rb content in liver0.70.83.6-0.20.11.00.40.80.7-0.61.11.9
Se content in liver0.30.31.5-0.30.41.2-0.60.30.3-0.40.40.5
Sr content in liver0.20.20.8-0.2-0.20.4-0.9-0.4-0.20.5-0.3-0.3
Zn content in liver11.012.919.4-4.24.43.5-2.7-3.7-4.43.5-3.80.1
Bone: minimum diameter2.44.612.43.5-2.6-0.71.72.42.3-2.01.61.3
Time in familiar zone, hab. session 10.30.30.70.30.40.00.50.80.8-0.70.7-0.1
Time in novel zone, hab. session 10.20.20.6-0.2-0.30.6-0.8-0.2-0.20.30.10.7
Total zone transitions, hab. session 12.63.77.31.1-1.8-2.52.71.52.1-2.31.7-0.2
Total locomotion distance, hab. session 10.40.61.80.6-0.5-1.21.30.50.7-0.70.5-0.4
Locomotion velocity, hab. session 10.40.62.30.5-0.5-1.51.30.20.4-0.50.1-0.8
Time in familiar zone, hab. session 21.11.33.30.21.21.1-1.8-0.5-0.61.7-0.9-1.0
Time in novel zone, hab. session 20.60.72.1-0.5-0.7-0.21.10.10.2-1.20.71.5
Total zone transitions, hab. session 22.43.16.71.2-1.7-2.52.61.31.7-1.91.4-0.2
Total locomotion distance, hab. session 20.50.72.80.7-0.9-1.71.10.00.4-0.30.0-0.7
Locomotion velocity, hab. session 20.40.62.50.4-0.8-1.61.1-0.10.3-0.3-0.0-0.7
Novel to familiar place preference ratio0.20.20.7-0.0-0.3-0.80.4-0.5-0.2-0.1-0.5-0.6
Novelty place preference0.20.31.0-0.0-0.4-1.00.4-0.5-0.2-0.1-0.6-0.9
Time in novel zone, NPP test0.30.31.10.0-0.4-1.10.4-0.5-0.2-0.1-0.6-0.9
Total zone transitions, NPP test1.92.95.91.5-2.0-2.32.41.21.6-1.71.10.0
Total locomotion distance, NPP test0.20.31.10.5-0.3-1.10.9-0.2-0.10.1-0.4-0.5
Locomotion velocity, NPP test0.30.41.30.6-0.3-1.10.8-0.5-0.20.4-0.7-0.7
Intraocular pressure0.20.31.0-0.20.11.0-0.80.30.20.20.60.9
Delta distance traveled before/after self-admin0.40.41.6-0.1-0.9-0.31.0-0.6-0.4-0.1-0.31.3
Delta ambulatory time before/after self-admin0.30.40.9-0.0-0.7-0.50.8-0.9-0.70.4-0.70.8
Parametrial fat weight0.20.41.70.30.01.20.10.50.1-0.70.11.3
Pavlov. Cond. lever latency0.40.52.20.6-0.7-1.50.4-0.2-0.30.1-0.2-1.0
Pavlov. Cond. magazine entry latency0.50.71.60.1-0.8-0.10.50.90.9-1.11.20.8
Pavlov. Cond. change in total contacts0.20.20.8-0.90.0-0.30.6-0.20.1-0.40.30.4
Pavlov. Cond. index score0.20.20.6-0.70.60.8-0.4-0.2-0.20.20.00.4
Pavlov. Cond. latency score0.30.41.2-0.80.71.1-0.6-0.2-0.20.3-0.00.6
Pavlov. Cond. lever contacts0.30.31.6-0.10.71.3-0.30.30.20.00.20.9
Pavlov. Cond. magazine entry number0.40.51.1-0.00.80.6-0.8-0.6-0.70.7-1.0-0.8
Pavlov. Cond. intertrial magazine entries0.20.31.10.20.21.0-0.00.20.3-0.00.21.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.8-0.90.70.6-0.5-0.5-0.40.4-0.20.1
Pavlov. Cond. response bias0.40.51.10.0-0.20.10.70.80.8-0.71.11.0
Pavlov. Cond. lever latency1.01.35.1-2.31.00.4-1.3-1.2-1.10.9-0.5-0.7
Pavlov. Cond. magazine entry latency0.00.10.2-0.30.20.5-0.2-0.10.2-0.10.10.2
Pavlov. Cond. change in total contacts0.10.20.80.9-0.40.30.50.40.3-0.2-0.10.6
Pavlov. Cond. index score0.10.20.90.80.20.9-0.10.40.30.00.10.4
Pavlov. Cond. latency score0.10.21.10.40.51.1-0.20.1-0.10.3-0.10.5
Pavlov. Cond. lever contacts0.91.35.62.4-1.0-0.01.01.31.1-0.80.60.8
Pavlov. Cond. magazine entry number0.10.10.9-0.2-0.3-0.90.2-0.1-0.3-0.0-0.1-0.4
Pavlov. Cond. intertrial magazine entries0.10.20.90.70.20.0-0.50.2-0.00.1-0.4-0.9
Pavlov. Cond. lever-magazine prob. diff.0.10.21.00.70.41.0-0.20.30.20.10.00.4
Pavlov. Cond. response bias1.21.75.32.3-1.2-0.11.11.51.5-1.21.00.7
Time in closed arm before self-admin0.10.20.4-0.30.2-0.60.5-0.5-0.50.6-0.5-0.6
Time in closed arm after self-admin0.50.61.2-0.70.4-0.60.4-1.1-0.90.8-1.1-0.6
Time in open arm before self-admin0.81.02.40.70.1-0.4-0.7-0.9-0.91.0-1.5-1.6
Time in open arm after self-admin0.40.51.20.4-0.60.2-0.10.70.7-0.71.10.9
Bone: periosteal estimation1.22.98.32.9-1.90.70.82.01.9-1.51.11.4
Bone: periosteal perimeter1.83.57.32.7-2.00.60.82.32.1-1.81.71.7
Bone: post-yield work0.50.92.60.1-0.50.70.91.00.5-1.40.71.6
Progressive ratio test 1 active lever presses1.62.86.11.4-2.4-2.52.10.91.6-1.41.10.1
Progressive ratio test 1 breakpoint1.52.66.21.4-2.3-2.52.10.81.4-1.30.90.1
Progressive ratio test 1 inactive lever presses0.10.31.40.0-0.8-1.20.0-0.10.2-0.0-0.0-1.0
Progressive ratio test 2 active lever presses0.40.51.21.1-0.9-0.90.80.40.8-0.40.50.1
Progressive ratio test 2 breakpoint0.30.41.01.0-0.7-0.90.70.20.6-0.30.3-0.2
Progressive ratio test 2 inactive lever presses0.10.30.80.4-0.3-0.10.20.60.8-0.30.90.2
Incentive Sensitization - Responses0.30.72.5-0.61.51.6-0.8-0.1-0.30.40.10.5
Incentive Sensitization - Breakpoint0.30.72.6-0.61.51.6-1.0-0.1-0.30.5-0.00.3
Sum of active levers in priming session hrs 5-66.25.89.4-2.22.3-0.0-2.0-2.9-3.03.1-2.6-2.2
Progressive ratio0.10.20.80.4-0.20.2-0.90.40.1-0.10.1-0.7
Food seeking constrained by brief footshock0.30.42.61.6-0.3-0.40.60.10.30.0-0.30.1
Seeking ratio, punishment vs. effort0.20.41.2-0.20.1-1.11.0-0.9-0.40.5-0.6-0.2
Retroperitoneal fat weight0.41.65.32.3-1.20.30.71.51.3-1.60.50.7
Reaction time number correct0.10.31.40.2-0.2-0.90.0-0.2-0.10.1-0.4-1.2
Reaction time mean minus median0.32.04.1-1.51.61.9-2.0-1.2-1.11.5-0.70.0
Reaction time mean minus median AUC0.42.44.3-1.61.81.8-2.1-1.4-1.41.9-0.9-0.0
Reaction time num false alarms1.22.04.40.2-1.5-0.51.01.61.8-2.02.10.9
Reaction time num false alarms AUC1.32.96.00.5-1.7-0.41.12.02.2-2.32.51.1
Reaction time trials correct on left0.10.31.40.2-0.2-0.90.0-0.2-0.10.1-0.4-1.2
Reaction time trials on left0.10.31.60.1-0.1-0.8-0.1-0.3-0.20.2-0.5-1.3
Reaction time mean0.81.84.0-0.91.20.6-2.0-1.3-1.21.8-1.1-1.5
Reaction time mean AUC0.61.63.5-0.91.00.4-1.9-1.3-1.21.7-1.0-1.4
Median of all reaction times0.81.23.3-0.40.7-0.2-1.5-1.0-0.91.4-1.0-1.8
Reaction time omissions1.62.55.7-2.01.72.2-2.4-1.3-1.21.3-0.60.0
Reaction time false alarm rate1.21.73.80.2-1.10.10.81.51.6-1.82.01.2
Reaction time premature initiation rate3.04.67.12.5-2.4-1.11.72.62.7-2.32.31.0
Reaction time premature initiations1.44.36.62.5-2.4-1.51.62.42.6-2.12.10.4
Std. dev. reaction times0.93.05.9-1.92.02.2-2.4-1.4-1.41.9-0.8-0.0
Reaction time trials completed0.10.31.60.1-0.1-0.8-0.1-0.3-0.20.2-0.5-1.3
Reaction time trials AUC0.10.31.20.3-0.3-0.90.1-0.2-0.10.1-0.3-1.1
Run reversals in cocaine runway, females0.80.91.8-1.00.3-0.4-0.5-1.2-0.81.0-1.2-1.3
Run reversals in cocaine runway, males1.61.83.9-1.0-0.1-2.00.0-1.9-1.21.0-1.2-1.9
Latency to leave start box in cocaine runway0.10.10.20.1-0.10.10.40.30.2-0.5-0.10.4
Latency to leave start box in cocaine runway, F0.60.82.70.6-0.70.21.00.80.7-0.90.81.7
Latency to leave start box in cocaine runway, M1.41.33.9-0.91.3-0.1-0.9-1.0-1.00.8-1.5-2.0
Std. dev. time between licks in bursts0.71.44.90.3-1.3-1.52.20.60.4-1.50.30.8
Total sessions with >9 infusions2.32.95.50.9-2.3-1.62.31.41.8-1.61.51.3
Short access day 1 total inactive lever presses0.40.82.40.5-0.8-1.31.60.60.7-1.00.4-0.1
Short access day 10 total inactive lever presses0.00.31.1-1.00.40.7-0.40.20.1-0.50.20.1
Short access day 1 total infusions1.32.54.60.3-1.8-1.22.11.51.8-1.81.81.4
Short access day 10 total infusions0.91.54.60.4-1.9-2.11.60.51.0-0.90.7-0.2
Short access total infusions1.52.25.20.6-2.3-2.32.00.71.3-1.20.90.0
Short access day 1 locomotion1.52.55.51.0-1.8-1.42.31.41.6-1.51.51.5
Short access day 10 total locomotion0.00.10.2-0.2-0.2-0.20.2-0.5-0.30.4-0.50.1
Short access total locomotion0.40.61.40.6-1.2-0.41.00.80.7-0.80.40.7
One hour access (0.3 mA shock)0.10.10.20.20.20.5-0.3-0.1-0.10.4-0.20.1
Compulsive drug intake0.20.30.90.00.60.6-1.0-0.2-0.40.3-0.5-0.8
One hour access (shock baseline)0.00.10.30.0-0.5-0.60.4-0.00.3-0.00.10.1
Social response proportion0.20.31.2-1.10.10.8-0.50.40.2-0.30.5-0.0
Social responses0.20.20.70.70.50.5-0.30.2-0.0-0.2-0.6-0.8
Social time1.01.54.2-1.01.62.1-1.6-0.7-1.01.1-0.7-0.2
Soleus weight1.13.25.42.3-2.1-0.61.02.32.2-1.72.00.9
Bone: stiffness0.51.03.31.8-1.4-0.61.00.70.9-0.80.10.3
Tibialis anterior weight2.27.730.25.5-2.9-2.41.52.92.8-1.51.8-0.9
Time to tail flick, vehicle, before self-admin0.30.31.3-0.50.41.1-0.20.20.2-0.60.50.8
Time to tail flick, vehicle, after self-admin0.91.94.10.30.02.0-0.41.81.4-1.41.61.7
Time to tail flick, test, before self-admin0.50.62.5-0.60.51.6-1.30.0-0.20.5-0.00.4
Time to tail flick, test, after self-admin0.10.10.30.30.20.40.20.30.1-0.30.30.5
Delta time to tail flick, vehicle, before/after SA1.61.73.31.2-1.2-0.10.91.81.6-1.61.41.0
Delta time to tail flick, test, before/after SA0.30.41.50.7-0.2-0.91.20.30.2-0.50.20.2
Tibia length0.20.74.12.0-0.40.5-0.50.70.70.10.30.2
Ambulatory time before self-admin0.20.71.6-0.20.61.1-0.31.31.0-0.81.00.3
Ambulatory time after self-admin0.40.62.9-0.60.31.20.20.40.4-0.40.71.7
Bone: tissue strength0.50.51.31.2-0.9-1.01.00.1-0.0-0.4-0.00.3
Total heroin consumption0.70.91.9-0.20.80.1-1.0-1.0-1.21.4-1.0-0.8
Bone: trabecular number0.40.71.8-0.91.11.3-1.1-0.5-0.60.6-0.20.2
Bone: trabecular spacing0.30.41.10.10.3-0.0-0.4-0.7-0.70.9-1.1-0.7
Bone: trabecular thickness0.10.20.80.1-0.0-0.8-0.0-0.3-0.2-0.1-0.0-0.9
Bone: trabecular tissue density0.20.30.8-0.4-0.3-0.9-0.1-0.8-0.40.4-0.3-0.7
Water consumed over 24 hours0.40.71.90.20.6-1.10.2-0.8-0.70.9-0.8-1.4
Number of responses in last shaping day3.74.77.11.0-2.5-1.02.12.32.6-2.62.71.9