Hub : Genes

Dcxr

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr10_106506441_106506555 0.03 0.02 3.4e-04 0.04 0.03 0.03 0.03 2.4e-05 3.5e-04 1.3e-04 2.2e-04
2 Liver intron excision ratio chr10_106506473_106506555 0.02 0.01 1.9e-03 0.04 0.02 0.03 0.02 6.9e-05 2.1e-03 2.6e-04 3.4e-03
3 Liver gene expression Dcxr 0.18 0.08 0.0e+00 0.23 0.23 0.23 0.23 1.6e-25 6.6e-25 1.0e-25 1.2e-25
4 Liver mRNA stability Dcxr 0.03 0.02 1.4e-03 0.03 0.02 0.02 0.02 4.0e-04 1.2e-03 1.2e-03 1.5e-03
5 RMTg gene expression Dcxr 0.12 0.09 8.6e-03 0.09 0.08 0.04 0.08 2.1e-03 3.4e-03 2.5e-02 3.8e-03
6 pVTA gene expression Dcxr 0.08 0.06 6.1e-05 0.07 0.05 0.03 0.05 4.6e-06 4.4e-05 1.1e-03 4.0e-05
7 PL gene expression Dcxr 0.05 0.03 2.6e-04 0.03 0.03 0.01 0.03 7.4e-04 3.6e-04 1.7e-02 9.1e-04
8 IC gene expression Dcxr 0.14 0.09 1.7e-03 0.01 0.03 0 0.02 1.1e-01 1.6e-02 1.9e-01 6.4e-02
9 Brain gene expression Dcxr 0.12 0.07 1.8e-07 0.06 0.07 0.07 0.07 1.9e-06 2.5e-07 2.5e-07 6.9e-07
10 NAcc gene expression Dcxr 0.12 0.09 2.4e-07 0.04 0.04 0.03 0.04 1.6e-06 3.9e-07 2.5e-05 2.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.20.40.6-0.60.00.00.10.20.60.60.70.2
Area under the delay curve0.91.01.9-1.41.41.21.21.11.10.30.0-0.10.9
BMI with tail0.30.93.41.9-1.9-0.4-0.2-0.2-0.30.40.60.50.8
BMI without tail1.13.411.83.4-3.4-1.3-1.2-1.0-1.00.91.51.5-0.0
Body weight1.25.214.63.8-3.8-2.5-2.4-2.1-2.2-0.50.20.2-0.7
Weight adjusted by age0.91.43.01.7-1.7-1.3-1.4-1.2-1.4-0.4-0.00.1-0.7
Bone surface0.10.20.30.4-0.4-0.6-0.6-0.3-0.4-0.10.10.2-0.6
Bone volume0.10.20.30.6-0.6-0.4-0.5-0.2-0.30.20.30.4-0.3
Breakpoint value in progressive ratio session1.82.13.30.3-0.3-1.8-1.7-1.8-1.8-1.6-1.4-1.4-1.4
Number of licking bursts0.20.41.00.2-0.20.40.30.50.50.90.91.00.7
Context. condit. distance diff. score1.62.04.90.8-0.81.00.90.90.81.92.12.21.4
Locomotion velocity, session 11.31.33.5-1.51.5-0.1-0.1-0.2-0.2-1.4-1.7-1.9-0.7
Locomotion distance, session 12.32.94.8-1.41.42.22.21.92.11.30.90.62.1
Locomotion velocity, session 21.72.05.6-2.42.41.41.41.21.3-0.2-0.7-0.90.7
Locomotion distance, session 20.81.22.2-0.20.21.41.41.01.21.11.00.71.5
Locomotion velocity, session 30.91.03.0-1.71.70.40.40.50.5-0.7-1.0-1.10.2
Locomotion distance, session 31.61.84.5-2.12.11.41.31.31.30.0-0.4-0.51.1
Stereotopy head waving bouts, day 30.30.30.8-0.70.7-0.00.10.30.1-0.6-0.8-0.9-0.1
Stereotopy head waving duration, day 30.20.20.4-0.60.60.30.40.50.4-0.2-0.4-0.40.3
Locomotion velocity, session 70.70.71.5-1.21.20.90.80.91.00.40.30.40.7
Locomotion distance, session 73.44.36.4-1.81.82.52.32.52.31.91.51.42.3
Stereotopy head waving bouts, day 70.10.10.40.6-0.6-0.5-0.3-0.1-0.5-0.2-0.1-0.1-0.2
Stereotopy head waving duration, day 70.10.10.40.6-0.6-0.4-0.2-0.1-0.4-0.1-0.00.0-0.2
Locomotion velocity, session 81.41.73.0-0.20.21.61.51.31.41.51.31.11.7
Locomotion distance, session 83.55.09.00.8-0.82.12.11.81.93.03.02.92.7
Degree of sensitization distance0.60.71.90.9-0.90.20.10.20.11.11.31.40.3
Degree of sensitization stereotypy0.10.20.60.8-0.8-0.2-0.1-0.1-0.30.20.30.30.0
Conditioned locomotion1.61.95.82.4-2.4-0.6-0.6-0.6-0.81.01.51.6-0.0
Cocaine response after cond. corrected0.30.41.0-0.30.3-0.5-0.4-0.5-0.6-0.9-0.9-1.0-0.6
Cocaine response after cond. not corrected0.30.30.8-0.80.80.00.10.0-0.0-0.6-0.8-0.9-0.2
Cocaine response before conditioning1.11.32.2-1.01.01.41.31.41.51.00.80.71.3
Saline control response1.01.33.92.0-2.0-1.0-0.9-0.8-0.80.40.81.0-0.5
Bone: connectivity density0.50.81.40.1-0.10.80.90.80.91.21.21.20.8
Bone: cortical apparent density1.21.74.7-2.22.21.21.21.41.20.0-0.4-0.50.8
Bone: cortical area3.45.312.63.6-3.6-2.6-2.6-2.3-2.2-1.1-0.7-0.8-1.0
Bone: cortical porosity3.74.05.80.5-0.5-2.2-2.4-2.0-1.9-2.4-2.3-2.2-2.2
Bone: cortical porosity3.53.86.00.9-0.9-2.3-2.5-2.1-2.0-2.2-2.0-1.9-2.1
Bone: cortical thickness4.16.811.63.4-3.4-3.1-3.1-2.7-2.7-2.0-1.6-1.8-1.4
Bone: cortical thickness1.11.32.11.4-1.4-1.3-1.4-1.2-1.2-0.9-0.8-0.9-0.4
Bone: cortical tissue density1.41.85.4-2.32.31.21.21.51.3-0.0-0.4-0.50.7
Condit. Reinf. active minus inactive responses1.11.23.61.9-1.9-0.9-0.9-1.2-0.90.10.40.4-0.5
Condit. Reinf. active-inactive response ratio0.40.41.21.1-1.1-0.6-0.7-0.7-0.6-0.00.20.1-0.1
Condit. Reinf. active responses1.82.37.52.7-2.7-1.2-1.1-1.5-1.20.30.80.8-0.7
Condit. Reinf. inactive responses0.50.72.21.5-1.5-0.5-0.4-0.7-0.50.30.50.6-0.5
Incentive salience index mean0.70.92.91.7-1.7-0.6-0.6-1.0-0.60.30.70.7-0.3
Condit. Reinf. lever presses0.40.61.10.1-0.10.70.80.30.81.01.01.00.8
Condit. Reinf. active minus inactive responses0.30.31.31.2-1.2-0.2-0.2-0.4-0.50.20.30.10.1
Condit. Reinf. active-inactive response ratio1.51.72.91.7-1.7-1.5-1.5-1.5-1.6-0.8-0.5-0.6-1.1
Condit. Reinf. active responses0.10.20.30.6-0.60.40.30.10.10.50.60.40.5
Condit. Reinf. inactive responses0.70.91.6-0.80.81.21.11.01.10.80.60.51.1
Condit. Reinf. lever presses0.30.40.90.7-0.70.40.40.20.20.91.00.90.6
Condit. Reinf. lever reinforcers received0.20.30.70.6-0.60.50.40.20.20.80.80.60.7
Conditioned reinforcement - actives0.20.30.60.2-0.20.70.60.60.70.50.40.50.8
Conditioned reinforcement - inactives0.10.10.30.5-0.5-0.5-0.4-0.4-0.4-0.10.0-0.0-0.2
Conditioned locomotion0.20.20.30.6-0.60.40.40.40.50.40.40.40.6
Patch foraging indifference point 0 sec0.00.00.10.1-0.1-0.3-0.2-0.1-0.1-0.00.10.1-0.2
Patch foraging indifference point AUC0.10.10.20.3-0.30.20.30.10.20.40.40.40.0
Delay disc. indifference point, 0s delay0.10.10.3-0.00.00.30.20.30.30.10.10.10.5
Delay disc. indifference point, 16s delay2.52.74.5-0.90.92.12.11.92.01.51.31.11.9
Delay disc. indifference point, 2s delay0.20.30.9-0.90.90.30.30.30.3-0.3-0.5-0.50.1
Delay disc. indifference point, 24s delay2.02.37.3-2.72.71.11.11.01.2-0.6-1.1-1.20.4
Delay disc. indifference point, 4s delay0.10.10.3-0.50.50.30.20.40.4-0.1-0.3-0.40.1
Delay disc. indifference point, 8s delay0.40.51.6-1.31.30.10.30.0-0.0-0.6-0.8-0.9-0.1
Indifference point function ln k0.40.81.4-1.01.01.00.91.21.10.40.10.11.1
Indifference point function log k0.40.81.4-1.01.01.00.91.21.10.40.10.11.1
Patch foraging total patch changes 0 sec0.00.00.10.2-0.2-0.2-0.1-0.10.00.10.20.2-0.1
Patch foraging total patch changes 12 sec0.20.30.80.3-0.3-0.6-0.6-0.6-0.5-0.4-0.4-0.4-0.9
Patch foraging total patch changes 18 sec0.40.51.00.2-0.20.80.80.70.71.01.00.90.8
Patch foraging total patch changes 24 sec0.20.30.91.0-1.0-0.5-0.4-0.5-0.30.10.30.4-0.2
Patch foraging total patch changes 6 sec0.30.40.80.6-0.6-0.8-0.8-0.8-0.6-0.5-0.4-0.4-0.9
Patch foraging time to switch 0 sec0.10.30.9-1.01.00.50.40.50.50.0-0.2-0.10.2
Patch foraging water rate 0 sec0.61.24.12.0-2.0-0.8-0.8-0.9-0.70.40.80.8-0.2
Patch foraging water rate 12 sec0.40.81.61.2-1.20.60.50.40.41.01.10.91.1
Patch foraging water rate 18 sec0.71.12.31.5-1.50.40.50.40.51.21.31.31.1
Patch foraging water rate 24 sec1.52.15.62.4-2.40.30.40.10.11.51.81.71.2
Patch foraging water rate 6 sec0.30.41.20.9-0.90.50.30.30.50.60.60.51.1
Seeking ratio, delayed vs. immediate footshock0.60.72.21.5-1.5-0.7-0.7-0.7-0.80.10.40.4-0.4
Distance traveled before self-admin1.01.32.40.5-0.5-1.5-1.5-1.5-1.3-1.0-0.8-0.6-1.1
Distance traveled after self-admin0.30.31.20.6-0.6-0.2-0.3-0.30.10.60.91.1-0.2
Extensor digitorum longus weight0.41.73.41.0-1.00.90.81.11.01.81.81.81.5
Bone: elastic displacement1.11.22.11.4-1.4-1.4-1.4-1.1-1.2-0.8-0.6-0.5-0.9
Bone: elastic work7.710.015.53.2-3.2-3.9-3.9-3.5-3.6-2.7-2.1-2.1-2.9
Bone: endosteal estimation0.40.91.70.1-0.10.90.91.00.81.21.21.30.9
Bone: endosteal perimeter0.30.61.01.0-1.0-1.0-0.9-0.9-0.8-0.20.00.2-0.8
Epididymis fat weight0.41.55.02.2-2.2-0.7-0.6-0.4-0.50.81.21.30.3
Delta time in closed arm before/after self-admin1.31.21.9-0.10.11.21.21.21.01.41.31.31.3
Delta time in open arm before/after self-admin0.00.00.1-0.20.20.10.10.10.3-0.0-0.00.10.2
Diff in mean of infusions in LGA sessions0.40.51.0-0.20.2-0.9-0.8-0.9-1.0-0.7-0.6-0.4-0.9
Delay discount exponential model param1.01.13.01.7-1.7-1.1-1.1-1.0-1.00.00.30.5-0.6
Extinction: sum of active levers before priming0.20.30.6-0.70.7-0.00.10.20.0-0.6-0.8-0.80.2
Active lever presses in extinction session 62.72.75.8-1.21.2-1.3-1.3-1.2-1.1-2.2-2.4-2.4-1.1
Bone: final force3.45.414.63.8-3.8-2.5-2.6-2.2-2.2-0.8-0.3-0.4-0.9
Bone: final moment4.26.716.24.0-4.0-2.9-3.0-2.6-2.6-1.2-0.6-0.7-1.3
Food consumed during 24 hour testing period0.10.10.20.4-0.4-0.4-0.5-0.4-0.30.10.30.4-0.3
Glucose5.68.720.4-3.73.7-0.8-0.8-1.1-1.1-3.7-4.3-4.5-2.0
Heart weight1.01.52.21.4-1.4-1.4-1.5-1.3-1.4-1.0-0.8-0.9-0.9
Delay discount hyperbolic model param0.91.02.81.7-1.7-1.0-1.0-0.9-0.90.10.40.6-0.5
Intermittent access intake day 1-15 change1.02.03.21.6-1.6-1.6-1.6-1.5-1.4-1.1-0.9-0.7-1.8
Intermittent access intake escalation0.81.72.61.6-1.6-1.4-1.5-1.3-1.3-0.9-0.7-0.6-1.6
Intermittent access intake escalation 23.53.95.41.8-1.8-2.3-2.3-2.3-2.3-1.7-1.4-1.2-2.3
Intermitt. access day 1 inactive lever presses0.51.76.12.5-2.5-0.9-0.8-0.7-0.70.71.01.0-0.4
Intermitt. access day 15 inactive lever presses0.40.81.91.4-1.40.10.20.20.21.01.11.20.4
Intermitt. access escalation Index0.40.51.31.0-1.00.30.30.20.20.91.01.10.3
Intermittent access day 1 total infusions0.10.10.40.6-0.6-0.0-0.1-0.10.00.00.10.00.2
Intermittent access day 15 total infusions0.50.82.91.7-1.7-0.7-0.8-0.7-0.6-0.2-0.1-0.0-0.6
Intermittent access terminal intake (last 3 days)0.71.02.41.6-1.6-1.0-1.0-1.0-1.0-0.4-0.2-0.1-0.9
Intermittent access total infusions0.20.31.11.1-1.1-0.3-0.4-0.3-0.3-0.00.10.1-0.2
Intermittent access day 1 locomotion0.10.10.40.4-0.40.30.30.30.30.20.20.20.6
Intermittent access day 15 total locomotion0.40.71.91.4-1.4-0.9-0.8-0.7-0.7-0.4-0.3-0.2-0.7
Intermittent access total locomotion0.20.31.01.0-1.0-0.4-0.4-0.3-0.3-0.2-0.1-0.1-0.1
Intermittent access standard deviation0.71.53.10.4-0.4-1.1-1.1-1.0-1.0-1.7-1.8-1.7-1.1
Left kidney weight0.10.61.40.4-0.4-0.7-0.7-0.6-0.5-1.0-1.0-1.2-0.4
Right kidney weight0.10.20.90.3-0.3-0.4-0.2-0.3-0.3-0.7-0.8-1.00.1
Cocaine induced anxiety3.85.48.00.3-0.3-2.8-2.6-2.8-2.6-2.7-2.5-2.5-2.1
Post-drug Anxiety3.63.86.6-0.80.8-1.9-1.8-2.2-1.8-2.4-2.5-2.6-1.8
Baseline Anxiety0.80.92.1-1.51.51.21.20.91.10.30.1-0.00.4
Tail length1.45.612.83.6-3.6-2.7-2.8-2.4-2.4-0.10.60.9-1.8
Length with tail1.35.59.72.2-2.2-3.1-3.1-2.7-2.7-1.8-1.3-1.1-2.2
Length without tail1.34.16.90.1-0.1-2.2-2.0-2.1-2.2-2.6-2.5-2.6-1.6
Times rat made contact with spout2.22.55.70.4-0.4-2.0-2.0-1.8-1.9-1.4-1.2-0.9-2.4
Lifetime Intake0.10.10.60.8-0.8-0.1-0.1-0.1-0.1-0.0-0.0-0.0-0.0
Liver weight, left0.40.61.9-1.41.40.20.10.50.5-0.6-0.9-0.90.1
Liver weight, right0.71.23.71.9-1.9-1.0-1.0-0.4-0.60.40.80.9-0.1
Locomotor activity0.30.41.2-1.11.10.70.70.80.50.0-0.2-0.20.5
Locomotor testing distance1.12.03.1-1.61.61.71.61.81.60.80.50.51.6
Locomotor testing rearing0.51.01.7-0.90.91.21.11.31.00.90.80.81.0
Locomotion in novel chamber0.60.71.2-0.70.70.91.10.80.90.80.70.71.1
Locomotion in novel chamber post-restriction1.42.34.42.1-2.1-1.8-1.7-1.7-1.6-0.30.20.4-1.6
Fecal boli incidents, locomotor time 10.50.72.1-0.40.41.10.91.11.40.70.60.50.9
Change in fecal boli incidents, locomotor task1.81.83.3-1.61.6-0.5-0.5-0.7-0.9-1.6-1.8-1.8-1.2
Time >=10cm from walls, locomotor time 11.01.02.61.1-1.10.50.50.40.41.41.51.60.5
Bouts of movement, locomotor time 10.50.61.6-1.31.30.70.60.80.9-0.2-0.5-0.50.4
Total resting periods, locomotor time 10.70.82.3-1.51.50.60.40.80.9-0.4-0.7-0.80.2
Rest time, locomotor task time 10.50.71.3-1.01.0-0.4-0.6-0.2-0.1-1.0-1.1-1.1-0.8
Distance moved, locomotor task time 10.20.20.50.7-0.7-0.10.0-0.2-0.60.40.60.70.3
Vertical activity count, locomotor time 10.30.81.71.2-1.20.00.2-0.0-0.30.91.21.30.7
Time >=10cm from walls, locomotor time 20.00.10.30.6-0.6-0.1-0.1-0.1-0.20.00.0-0.10.0
Bouts of movement, locomotor time 20.50.81.3-1.11.10.91.01.01.10.40.20.10.9
Total resting periods, locomotor time 20.50.91.5-0.80.81.11.11.21.20.80.60.51.1
Rest time, locomotor task time 20.00.00.2-0.40.40.00.00.20.10.10.10.2-0.2
Distance moved, locomotor task time 20.00.00.20.3-0.30.10.10.0-0.20.00.0-0.10.4
Vertical activity count, locomotor time 20.40.51.20.7-0.70.60.60.60.50.80.80.61.1
Light reinforcement 10.71.64.51.4-1.40.40.50.40.21.61.92.11.0
Light reinforcement 20.71.13.01.7-1.7-0.5-0.4-0.4-0.50.81.21.30.3
Bone: marrow area0.40.81.60.1-0.10.90.91.00.81.21.21.30.9
Bone: maximum diameter0.71.43.51.9-1.9-1.4-1.3-1.2-1.1-0.5-0.2-0.2-0.5
Bone: maximum force3.05.315.94.0-4.0-2.3-2.4-2.1-2.2-0.6-0.0-0.2-0.8
Bone: maximum moment3.76.517.04.1-4.1-2.7-2.8-2.5-2.6-0.9-0.4-0.5-1.2
Mean time between licks in bursts0.51.11.9-1.41.41.31.11.31.40.40.1-0.01.0
Mean num. licks in bursts1.01.53.20.1-0.1-1.4-1.3-1.4-1.4-1.3-1.2-1.2-1.8
Cd content in liver1.11.22.0-0.20.21.21.01.41.21.41.31.21.2
Co content in liver0.00.00.1-0.00.0-0.3-0.30.10.0-0.0-0.00.1-0.2
Cu content in liver1.51.82.80.8-0.8-1.7-1.7-1.4-1.5-1.3-1.1-1.0-1.6
Fe content in liver0.60.71.2-0.80.80.90.81.11.10.70.60.61.0
K content in liver1.31.33.81.0-1.00.40.30.50.51.61.81.90.8
Mg content in liver2.82.86.50.6-0.61.41.31.41.32.42.52.51.6
Mn content in liver0.00.00.20.4-0.40.10.10.0-0.00.20.20.10.2
Na content in liver0.50.61.0-0.30.30.70.70.70.80.90.91.00.9
Rb content in liver1.21.43.92.0-2.00.00.1-0.1-0.31.31.51.50.5
Se content in liver0.10.10.50.4-0.4-0.1-0.0-0.20.10.40.60.7-0.1
Sr content in liver1.41.22.3-0.70.7-0.8-0.7-0.9-1.0-1.5-1.5-1.5-1.2
Zn content in liver0.70.72.11.4-1.4-0.6-0.8-0.5-0.50.50.80.8-0.5
Bone: minimum diameter1.73.26.52.5-2.5-2.2-2.1-1.8-1.8-0.9-0.4-0.2-1.3
Time in familiar zone, hab. session 10.30.30.60.1-0.1-0.4-0.4-0.5-0.6-0.7-0.7-0.8-0.6
Time in novel zone, hab. session 10.20.20.30.0-0.00.30.30.50.40.50.50.60.5
Total zone transitions, hab. session 10.20.30.9-0.30.30.80.70.50.80.50.40.20.9
Total locomotion distance, hab. session 10.30.40.90.5-0.50.50.50.40.50.80.80.80.9
Locomotion velocity, hab. session 10.30.50.90.5-0.50.50.60.40.60.80.90.81.0
Time in familiar zone, hab. session 20.20.20.4-0.40.40.50.50.60.40.40.30.30.5
Time in novel zone, hab. session 20.00.00.10.0-0.00.20.10.10.20.0-0.0-0.10.2
Total zone transitions, hab. session 21.92.53.90.2-0.21.71.71.41.72.01.91.71.9
Total locomotion distance, hab. session 21.92.54.81.1-1.11.31.30.91.32.12.22.11.7
Locomotion velocity, hab. session 21.72.24.41.4-1.41.01.10.71.02.02.12.01.5
Novel to familiar place preference ratio3.03.24.81.6-1.6-2.2-2.2-2.1-2.2-1.6-1.3-1.2-1.8
Novelty place preference3.13.34.91.6-1.6-2.2-2.1-2.1-2.2-1.6-1.3-1.2-1.9
Time in novel zone, NPP test2.32.53.81.5-1.5-1.9-1.9-1.8-1.9-1.4-1.1-1.0-1.6
Total zone transitions, NPP test2.94.26.2-0.10.12.32.32.02.32.52.42.22.4
Total locomotion distance, NPP test3.04.16.90.6-0.61.92.11.61.92.62.62.52.4
Locomotion velocity, NPP test1.92.74.80.7-0.71.41.61.21.42.12.22.11.8
Intraocular pressure0.40.51.91.4-1.4-0.3-0.3-0.4-0.40.50.70.7-0.3
Delta distance traveled before/after self-admin0.80.91.4-0.30.31.11.01.01.21.11.01.10.8
Delta ambulatory time before/after self-admin1.62.03.4-0.80.81.81.71.61.81.41.31.31.2
Parametrial fat weight0.20.51.41.2-1.2-0.3-0.4-0.2-0.10.70.91.00.1
Pavlov. Cond. lever latency2.12.64.3-0.60.61.91.82.11.71.81.61.51.9
Pavlov. Cond. magazine entry latency3.14.06.41.3-1.3-2.4-2.4-2.5-2.3-1.9-1.6-1.5-2.2
Pavlov. Cond. change in total contacts1.92.13.30.1-0.1-1.6-1.4-1.5-1.4-1.8-1.8-1.7-1.6
Pavlov. Cond. index score2.83.66.21.7-1.7-2.3-2.3-2.5-2.2-1.6-1.2-1.0-2.0
Pavlov. Cond. latency score2.83.66.21.3-1.3-2.3-2.2-2.5-2.2-1.7-1.4-1.2-2.1
Pavlov. Cond. lever contacts0.91.12.30.6-0.6-1.2-1.2-1.5-1.1-1.0-0.8-0.7-1.1
Pavlov. Cond. magazine entry number4.75.98.5-1.21.22.92.82.92.72.52.22.12.8
Pavlov. Cond. intertrial magazine entries0.70.81.70.9-0.90.60.60.60.51.21.31.30.7
Pavlov. Cond. lever-magazine prob. diff.2.73.45.71.6-1.6-2.3-2.2-2.4-2.1-1.5-1.2-1.0-1.9
Pavlov. Cond. response bias3.44.26.31.1-1.1-2.4-2.4-2.5-2.2-2.1-1.9-1.8-2.3
Pavlov. Cond. lever latency0.70.92.2-1.21.2-0.3-0.2-0.1-0.2-1.2-1.5-1.5-0.6
Pavlov. Cond. magazine entry latency2.12.53.9-1.21.22.01.81.92.01.51.21.21.8
Pavlov. Cond. change in total contacts0.50.81.2-0.20.21.11.00.90.91.11.11.01.0
Pavlov. Cond. index score0.50.71.1-0.10.11.00.80.80.91.11.01.00.9
Pavlov. Cond. latency score0.71.01.6-0.10.11.11.00.91.01.31.21.21.1
Pavlov. Cond. lever contacts0.60.92.21.0-1.00.40.40.20.31.31.51.50.6
Pavlov. Cond. magazine entry number1.51.92.81.0-1.0-1.7-1.5-1.5-1.7-1.3-1.1-1.1-1.5
Pavlov. Cond. intertrial magazine entries0.61.03.31.8-1.8-0.7-0.7-0.8-0.90.20.50.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.60.81.2-0.40.41.11.00.91.01.01.00.91.0
Pavlov. Cond. response bias0.50.71.30.2-0.20.90.70.50.71.11.11.10.9
Time in closed arm before self-admin0.60.71.8-0.50.5-0.6-0.6-0.7-0.3-1.2-1.3-1.3-0.8
Time in closed arm after self-admin0.70.71.5-1.21.2-0.2-0.2-0.3-0.2-0.9-1.1-1.2-0.6
Time in open arm before self-admin1.11.21.90.5-0.51.11.01.10.91.41.41.31.2
Time in open arm after self-admin0.50.60.90.4-0.40.80.70.70.80.80.80.81.0
Bone: periosteal estimation0.71.65.12.3-2.3-1.3-1.2-1.0-1.1-0.10.20.2-0.3
Bone: periosteal perimeter3.45.98.92.4-2.4-3.0-3.0-2.8-2.7-2.1-1.7-1.5-2.2
Bone: post-yield work0.20.20.40.2-0.20.50.50.50.40.60.60.50.7
Progressive ratio test 1 active lever presses0.30.31.41.2-1.2-0.3-0.4-0.3-0.30.10.20.3-0.1
Progressive ratio test 1 breakpoint0.30.41.61.3-1.3-0.4-0.5-0.4-0.40.00.20.3-0.1
Progressive ratio test 1 inactive lever presses1.41.97.02.6-2.6-0.6-0.6-0.5-0.50.91.31.40.1
Progressive ratio test 2 active lever presses0.20.31.21.1-1.1-0.2-0.2-0.2-0.10.20.30.2-0.2
Progressive ratio test 2 breakpoint0.30.31.31.1-1.1-0.2-0.3-0.3-0.20.10.20.2-0.3
Progressive ratio test 2 inactive lever presses0.30.51.31.1-1.1-0.7-0.7-0.7-0.7-0.5-0.4-0.4-0.6
Incentive Sensitization - Responses0.10.20.60.8-0.8-0.2-0.2-0.2-0.10.30.40.3-0.4
Incentive Sensitization - Breakpoint0.10.10.50.7-0.7-0.2-0.2-0.2-0.10.20.20.2-0.5
Sum of active levers in priming session hrs 5-62.11.92.90.2-0.2-1.6-1.6-1.7-1.7-1.5-1.4-1.3-1.6
Progressive ratio0.30.40.9-0.90.90.70.70.80.8-0.0-0.3-0.40.5
Food seeking constrained by brief footshock0.70.81.4-0.90.9-0.7-0.7-0.7-0.5-1.1-1.2-1.1-1.0
Seeking ratio, punishment vs. effort0.00.10.20.3-0.3-0.2-0.1-0.1-0.10.20.30.4-0.1
Retroperitoneal fat weight1.04.313.43.7-3.7-1.6-1.2-1.3-1.31.11.82.1-0.3
Reaction time number correct3.66.911.80.9-0.92.52.42.32.43.43.43.43.1
Reaction time mean minus median0.20.40.8-0.60.6-0.5-0.3-0.4-0.6-0.9-0.9-0.7-0.8
Reaction time mean minus median AUC0.00.00.1-0.10.1-0.2-0.2-0.2-0.2-0.3-0.3-0.2-0.2
Reaction time num false alarms0.10.10.4-0.60.60.20.20.30.2-0.0-0.1-0.1-0.0
Reaction time num false alarms AUC0.20.40.7-0.90.90.70.70.70.70.30.10.10.4
Reaction time trials correct on left3.66.911.80.9-0.92.52.42.32.43.43.43.43.1
Reaction time trials on left3.87.112.20.9-0.92.62.42.32.43.43.53.43.1
Reaction time mean0.10.20.40.6-0.6-0.4-0.2-0.3-0.60.20.30.4-0.0
Reaction time mean AUC0.20.30.80.7-0.70.10.30.2-0.10.70.80.90.5
Median of all reaction times0.20.30.70.9-0.9-0.2-0.1-0.1-0.40.50.60.70.3
Reaction time omissions0.10.20.50.3-0.30.10.40.2-0.00.50.60.70.4
Reaction time false alarm rate1.01.32.6-1.21.2-0.7-0.6-0.5-0.6-1.4-1.6-1.6-1.2
Reaction time premature initiation rate0.50.71.8-1.31.30.90.90.81.00.0-0.3-0.40.2
Reaction time premature initiations1.62.84.5-0.60.62.12.01.92.11.81.61.41.7
Std. dev. reaction times0.10.10.3-0.50.50.40.50.40.20.10.10.20.2
Reaction time trials completed3.87.112.20.9-0.92.62.42.32.43.43.53.43.1
Reaction time trials AUC3.77.012.21.0-1.02.52.42.32.43.43.53.43.1
Run reversals in cocaine runway, females1.11.11.8-0.40.41.31.31.21.31.11.00.91.0
Run reversals in cocaine runway, males2.02.03.30.6-0.6-1.8-1.8-1.8-1.8-1.3-1.1-0.9-1.8
Latency to leave start box in cocaine runway0.50.51.2-0.30.30.90.81.10.90.70.60.50.7
Latency to leave start box in cocaine runway, F2.32.64.20.2-0.21.81.72.01.71.91.81.71.8
Latency to leave start box in cocaine runway, M0.50.50.8-0.50.5-0.6-0.6-0.6-0.6-0.8-0.9-0.9-0.8
Std. dev. time between licks in bursts2.83.77.01.2-1.21.61.61.61.52.52.72.62.2
Total sessions with >9 infusions0.10.10.4-0.10.10.50.40.70.50.1-0.1-0.10.5
Short access day 1 total inactive lever presses0.50.71.50.1-0.10.80.81.00.90.90.80.71.2
Short access day 10 total inactive lever presses0.41.02.31.5-1.5-1.1-1.0-0.8-1.00.40.80.7-0.5
Short access day 1 total infusions0.70.91.9-1.01.01.11.11.41.10.3-0.0-0.11.1
Short access day 10 total infusions0.91.22.01.4-1.4-1.3-1.3-1.1-1.3-0.6-0.4-0.2-1.0
Short access total infusions0.00.00.00.2-0.2-0.00.00.1-0.0-0.1-0.2-0.10.1
Short access day 1 locomotion0.20.20.7-0.10.1-0.2-0.2-0.0-0.2-0.7-0.8-0.8-0.1
Short access day 10 total locomotion0.61.12.3-0.30.3-1.0-1.0-0.8-1.0-1.4-1.5-1.5-1.0
Short access total locomotion0.60.71.40.5-0.5-0.8-0.8-0.6-0.8-1.2-1.2-1.2-0.7
One hour access (0.3 mA shock)0.40.51.91.4-1.40.0-0.10.00.20.40.50.60.0
Compulsive drug intake0.60.71.90.9-0.90.40.40.40.31.21.31.40.7
One hour access (shock baseline)0.10.10.50.7-0.70.20.10.10.30.20.20.30.1
Social response proportion0.40.40.8-0.50.50.80.70.80.60.60.50.40.9
Social responses0.40.51.3-0.50.50.70.70.90.80.60.50.51.1
Social time0.20.30.90.2-0.20.50.50.70.50.50.40.30.9
Soleus weight0.61.95.12.2-2.2-1.4-1.4-1.2-1.4-0.00.40.5-0.9
Bone: stiffness0.40.62.51.6-1.6-0.3-0.5-0.3-0.40.10.30.00.6
Tibialis anterior weight0.10.40.70.5-0.50.40.40.50.50.80.80.80.6
Time to tail flick, vehicle, before self-admin0.10.10.2-0.30.30.40.40.40.30.10.10.00.2
Time to tail flick, vehicle, after self-admin1.11.52.5-1.31.31.51.41.61.60.50.1-0.01.3
Time to tail flick, test, before self-admin0.10.10.3-0.60.6-0.1-0.0-0.1-0.0-0.3-0.4-0.5-0.5
Time to tail flick, test, after self-admin0.80.82.4-1.51.50.00.00.10.1-0.8-1.0-1.1-0.3
Delta time to tail flick, vehicle, before/after SA0.50.50.8-0.00.00.80.70.80.90.80.70.70.9
Delta time to tail flick, test, before/after SA0.40.41.1-0.80.8-0.2-0.2-0.2-0.2-0.9-1.0-1.0-0.1
Tibia length7.019.232.85.7-5.7-5.1-5.1-4.9-4.9-2.7-1.8-1.8-3.5
Ambulatory time before self-admin1.42.13.81.3-1.3-1.9-1.9-1.9-1.8-1.0-0.7-0.5-1.3
Ambulatory time after self-admin0.20.20.60.6-0.6-0.2-0.3-0.30.00.40.60.8-0.1
Bone: tissue strength1.11.14.12.0-2.0-0.6-0.6-0.2-0.40.50.80.70.4
Total heroin consumption1.01.22.1-0.50.5-1.2-1.0-1.1-1.2-1.4-1.4-1.3-0.6
Bone: trabecular number0.00.00.1-0.10.1-0.1-0.2-0.2-0.1-0.1-0.0-0.0-0.3
Bone: trabecular spacing2.43.25.80.8-0.81.61.51.51.52.32.42.42.1
Bone: trabecular thickness2.63.35.20.5-0.5-2.1-2.1-1.9-1.9-2.0-1.9-1.8-2.3
Bone: trabecular tissue density0.40.61.1-1.01.01.00.81.00.90.30.10.00.8
Water consumed over 24 hours0.60.81.2-0.70.7-0.8-0.9-0.7-0.7-1.1-1.1-1.0-1.1
Number of responses in last shaping day0.10.10.40.4-0.40.20.20.30.3-0.0-0.1-0.20.6