Hub : Genes

Dcxr

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr10_106008115_106008229 0.03 0.02 7.5e-04 0.02 0.03 0.02 0.02 5.5e-03 8.1e-04 1.5e-03 2.2e-03
2 Liver intron excision ratio chr10_106008147_106008229 0.02 0.01 3.0e-03 0.01 0.02 0.01 0.01 2.3e-02 3.2e-03 1.6e-02 1.4e-02
3 Liver mRNA stability Dcxr 0.03 0.02 1.9e-03 0.02 0.02 0.03 0.03 1.1e-03 1.6e-03 3.7e-04 3.2e-04
4 Liver gene expression Dcxr 0.2 0.08 0.0e+00 0.27 0.26 0.25 0.26 1.2e-29 5.6e-29 5.0e-27 9.3e-29
5 RMTg gene expression Dcxr 0.13 0.09 5.5e-03 0.09 0.11 0.06 0.1 2.2e-03 7.0e-04 8.5e-03 1.1e-03
6 BLA gene expression Dcxr 0.06 0.05 8.3e-03 0 0.02 -0 0 1.7e-01 3.3e-02 7.2e-01 3.0e-01
7 PL gene expression Dcxr 0.04 0.03 7.8e-04 0.01 0.02 0.01 0.01 4.1e-02 1.3e-03 2.4e-02 1.9e-02
8 Brain gene expression Dcxr 0.12 0.08 2.9e-07 0.05 0.08 0.06 0.07 4.3e-05 6.4e-08 3.4e-06 2.6e-07
9 NAcc gene expression Dcxr 0.2 0.16 1.8e-05 0.03 0.03 0.04 0.03 1.2e-04 1.8e-04 2.9e-05 3.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.20.50.3-0.30.1-0.20.30.60.60.7-0.2
Area under the delay curve0.90.91.9-1.41.41.0-1.10.80.20.2-0.3-1.3
BMI with tail0.30.93.81.2-1.2-0.40.50.10.40.50.6-1.9
BMI without tail1.94.08.83.0-3.0-0.60.70.32.02.12.9-0.1
Body weight1.35.617.04.1-4.1-2.62.5-1.8-0.5-0.30.5-0.5
Weight adjusted by age1.51.73.31.8-1.8-1.51.6-1.3-0.8-0.7-0.20.9
Bone surface0.10.20.60.6-0.6-0.40.6-0.4-0.00.00.30.8
Bone volume0.10.20.30.6-0.6-0.20.4-0.10.20.30.50.6
Breakpoint value in progressive ratio session1.41.52.50.9-0.9-1.61.4-1.4-1.4-1.4-1.20.5
Number of licking bursts0.30.40.90.1-0.10.7-0.30.50.80.81.0-0.5
Context. condit. distance diff. score1.41.74.30.2-0.20.9-1.01.31.81.92.1-0.9
Locomotion velocity, session 11.01.13.2-1.21.2-0.10.1-0.4-1.2-1.3-1.80.5
Locomotion distance, session 12.93.75.4-2.22.22.2-2.22.11.51.40.8-2.3
Locomotion velocity, session 21.82.15.7-2.42.41.3-1.41.10.1-0.0-0.7-1.3
Locomotion distance, session 21.31.83.5-1.01.01.4-1.51.51.31.30.9-1.9
Locomotion velocity, session 30.60.71.9-1.41.40.5-0.40.2-0.6-0.6-1.1-0.7
Locomotion distance, session 31.51.74.0-2.02.01.3-1.31.00.20.1-0.5-1.5
Stereotopy head waving bouts, day 30.20.30.7-0.70.70.2-0.1-0.1-0.6-0.6-0.9-0.1
Stereotopy head waving duration, day 30.10.20.3-0.60.60.5-0.30.2-0.2-0.2-0.4-0.4
Locomotion velocity, session 70.50.61.1-1.01.00.9-0.80.80.50.40.2-0.8
Locomotion distance, session 73.64.55.6-2.32.32.3-2.32.41.91.81.3-2.3
Stereotopy head waving bouts, day 70.00.00.20.4-0.40.10.0-0.1-0.0-0.00.1-0.2
Stereotopy head waving duration, day 70.10.20.50.7-0.7-0.20.3-0.5-0.3-0.2-0.00.1
Locomotion velocity, session 81.72.14.2-1.01.01.3-1.51.71.51.51.1-2.1
Locomotion distance, session 83.65.28.7-0.50.52.0-2.22.52.92.92.9-2.5
Degree of sensitization distance0.50.51.60.5-0.50.0-0.10.41.01.01.30.1
Degree of sensitization stereotypy0.10.10.40.7-0.7-0.10.1-0.20.10.10.3-0.2
Conditioned locomotion1.21.44.42.1-2.1-0.70.6-0.30.70.81.40.2
Cocaine response after cond. corrected0.30.30.80.0-0.0-0.60.6-0.6-0.8-0.8-0.90.2
Cocaine response after cond. not corrected0.20.20.6-0.60.5-0.10.1-0.1-0.5-0.5-0.8-0.3
Cocaine response before conditioning1.11.31.7-1.21.21.2-1.31.21.00.90.7-1.3
Saline control response1.21.54.32.1-2.1-1.31.2-1.0-0.1-0.10.50.9
Bone: connectivity density0.50.91.6-0.30.30.9-0.91.01.21.21.3-0.6
Bone: cortical apparent density0.91.13.4-1.81.81.2-0.80.7-0.1-0.2-0.7-0.6
Bone: cortical area3.35.011.23.4-3.3-2.72.7-2.0-1.4-1.2-0.8-0.6
Bone: cortical porosity4.85.27.21.4-1.4-2.32.5-2.6-2.7-2.7-2.52.1
Bone: cortical porosity3.94.25.41.5-1.5-2.12.3-2.3-2.3-2.3-2.02.0
Bone: cortical thickness4.26.911.33.4-3.3-3.23.1-2.6-2.3-2.1-1.9-0.6
Bone: cortical thickness1.51.72.71.6-1.6-1.51.5-1.2-1.1-1.1-1.1-1.0
Bone: cortical tissue density1.01.34.0-2.02.01.3-0.90.7-0.1-0.2-0.7-0.5
Condit. Reinf. active minus inactive responses0.91.02.81.7-1.7-1.10.9-0.7-0.00.00.40.7
Condit. Reinf. active-inactive response ratio0.40.41.11.1-1.1-0.70.7-0.5-0.1-0.10.20.0
Condit. Reinf. active responses1.51.85.32.3-2.3-1.41.1-0.90.20.20.81.1
Condit. Reinf. inactive responses0.50.61.41.2-1.2-0.70.5-0.40.20.20.51.0
Incentive salience index mean0.60.72.11.4-1.4-0.80.7-0.40.30.30.70.5
Condit. Reinf. lever presses0.40.51.2-0.20.20.7-0.60.71.01.01.1-0.5
Condit. Reinf. active minus inactive responses0.30.41.21.1-1.1-0.70.6-0.30.00.00.1-0.2
Condit. Reinf. active-inactive response ratio1.71.83.31.8-1.8-1.71.6-1.3-0.9-0.8-0.60.9
Condit. Reinf. active responses0.10.10.20.5-0.5-0.30.10.10.40.30.3-0.4
Condit. Reinf. inactive responses0.50.61.0-0.80.80.8-0.90.80.60.60.4-1.0
Condit. Reinf. lever presses0.20.30.60.3-0.30.2-0.20.40.70.70.8-0.5
Condit. Reinf. lever reinforcers received0.10.20.30.4-0.4-0.1-0.10.30.60.60.5-0.6
Conditioned reinforcement - actives0.80.81.7-0.20.21.1-0.80.80.91.01.0-1.3
Conditioned reinforcement - inactives0.80.91.91.3-1.3-1.41.1-1.0-0.6-0.5-0.30.1
Conditioned locomotion0.10.10.30.1-0.00.4-0.20.20.40.40.5-0.3
Patch foraging indifference point 0 sec0.00.00.10.3-0.3-0.00.1-0.3-0.1-0.10.10.2
Patch foraging indifference point AUC0.00.00.2-0.0-0.00.10.00.20.30.30.20.4
Delay disc. indifference point, 0s delay0.20.21.2-0.20.30.4-0.30.20.00.0-0.1-1.1
Delay disc. indifference point, 16s delay3.33.35.4-1.71.72.2-2.11.91.51.51.1-2.3
Delay disc. indifference point, 2s delay0.10.20.3-0.60.60.2-0.30.1-0.2-0.3-0.5-0.4
Delay disc. indifference point, 24s delay1.61.64.8-2.22.20.9-1.10.6-0.4-0.5-1.1-0.9
Delay disc. indifference point, 4s delay0.20.20.4-0.60.60.5-0.30.2-0.1-0.1-0.4-0.7
Delay disc. indifference point, 8s delay0.40.41.1-0.70.7-0.0-0.2-0.2-0.7-0.7-1.0-0.6
Indifference point function ln k0.71.03.3-1.21.21.0-1.10.90.40.4-0.0-1.8
Indifference point function log k0.71.03.3-1.21.21.0-1.10.90.40.4-0.0-1.8
Patch foraging total patch changes 0 sec0.00.00.10.3-0.30.10.0-0.10.00.10.2-0.1
Patch foraging total patch changes 12 sec0.20.30.90.3-0.3-0.40.6-0.5-0.4-0.4-0.41.0
Patch foraging total patch changes 18 sec0.40.60.8-0.40.40.9-0.70.80.90.90.9-0.6
Patch foraging total patch changes 24 sec0.20.20.60.8-0.8-0.40.3-0.30.00.10.40.2
Patch foraging total patch changes 6 sec0.40.50.80.8-0.9-0.70.8-0.8-0.6-0.5-0.30.9
Patch foraging time to switch 0 sec0.10.20.7-0.80.80.6-0.30.30.0-0.0-0.20.0
Patch foraging water rate 0 sec0.71.13.31.8-1.8-1.10.8-0.50.30.40.8-0.2
Patch foraging water rate 12 sec0.50.72.90.3-0.30.4-0.60.70.90.90.8-1.7
Patch foraging water rate 18 sec0.71.02.40.5-0.50.4-0.60.81.21.21.3-1.6
Patch foraging water rate 24 sec1.01.32.91.2-1.20.3-0.40.61.31.41.7-1.4
Patch foraging water rate 6 sec0.50.74.90.1-0.10.0-0.40.60.60.60.5-2.2
Seeking ratio, delayed vs. immediate footshock0.50.61.91.4-1.4-0.50.7-0.50.00.10.40.3
Distance traveled before self-admin2.32.43.61.5-1.5-1.91.9-1.8-1.5-1.5-1.01.4
Distance traveled after self-admin0.40.41.10.6-0.6-0.10.10.00.60.61.11.0
Extensor digitorum longus weight0.52.13.9-0.10.11.3-0.91.51.91.92.0-1.5
Bone: elastic displacement1.21.42.31.5-1.4-1.31.5-1.2-1.0-0.9-0.70.9
Bone: elastic work8.010.315.13.7-3.6-3.83.9-3.4-2.9-2.8-2.22.0
Bone: endosteal estimation0.40.92.1-0.30.20.9-0.81.01.31.31.4-0.4
Bone: endosteal perimeter0.30.71.41.2-1.2-0.90.9-0.7-0.2-0.10.31.0
Epididymis fat weight0.30.71.81.3-1.3-0.40.4-0.10.60.71.1-0.6
Delta time in closed arm before/after self-admin0.50.51.2-0.40.40.9-0.70.70.70.70.6-1.1
Delta time in open arm before/after self-admin0.10.10.2-0.00.10.1-0.20.20.30.30.40.0
Diff in mean of infusions in LGA sessions0.10.10.3-0.50.50.2-0.1-0.1-0.3-0.3-0.2-0.1
Delay discount exponential model param0.91.02.41.6-1.5-1.01.0-0.70.00.10.61.1
Extinction: sum of active levers before priming0.50.51.3-1.11.2-0.1-0.30.1-0.7-0.7-0.9-0.3
Active lever presses in extinction session 61.21.12.6-0.20.2-1.20.8-0.9-1.5-1.5-1.6-0.6
Bone: final force2.84.510.93.3-3.2-2.52.5-1.8-1.2-1.0-0.7-0.8
Bone: final moment3.55.713.03.6-3.5-2.82.9-2.2-1.5-1.3-0.9-0.3
Food consumed during 24 hour testing period0.30.41.10.7-0.7-1.00.5-0.30.10.10.40.9
Glucose3.14.613.2-1.21.1-1.31.1-1.7-3.0-3.1-3.61.3
Heart weight0.30.40.90.9-0.9-0.80.7-0.6-0.5-0.4-0.40.2
Delay discount hyperbolic model param0.91.02.31.5-1.5-1.01.0-0.7-0.00.10.61.1
Intermittent access intake day 1-15 change0.90.92.21.1-1.1-0.91.1-0.9-0.5-0.4-0.11.5
Intermittent access intake escalation0.50.51.50.9-0.9-0.60.8-0.6-0.1-0.10.21.2
Intermittent access intake escalation 22.92.94.61.7-1.7-1.82.0-1.9-1.4-1.4-0.82.1
Intermitt. access day 1 inactive lever presses1.41.53.91.3-1.3-2.01.4-1.2-0.9-0.9-0.60.7
Intermitt. access day 15 inactive lever presses0.30.30.80.9-0.9-0.30.10.00.50.60.8-0.4
Intermitt. access escalation Index0.80.72.20.5-0.50.4-0.60.61.21.21.5-0.4
Intermittent access day 1 total infusions0.10.10.40.7-0.7-0.20.3-0.20.10.10.2-0.3
Intermittent access day 15 total infusions0.20.30.80.9-0.9-0.30.4-0.30.30.30.60.3
Intermittent access terminal intake (last 3 days)0.50.61.61.3-1.3-0.50.8-0.7-0.1-0.10.30.7
Intermittent access total infusions0.20.20.70.8-0.8-0.30.3-0.20.20.20.5-0.1
Intermittent access day 1 locomotion0.30.31.50.4-0.40.1-0.10.20.50.50.5-1.2
Intermittent access day 15 total locomotion0.30.30.60.8-0.8-0.60.7-0.6-0.3-0.3-0.10.5
Intermittent access total locomotion0.20.20.50.7-0.7-0.60.4-0.3-0.00.00.1-0.5
Intermittent access standard deviation1.31.42.8-0.00.0-1.11.1-1.2-1.6-1.6-1.70.6
Left kidney weight0.20.51.10.4-0.4-0.70.6-0.6-0.9-0.8-1.0-0.4
Right kidney weight0.10.21.8-0.00.1-0.0-0.00.1-0.2-0.2-0.5-1.3
Cocaine induced anxiety7.28.315.82.8-2.8-4.03.4-3.2-2.8-2.7-2.11.6
Post-drug Anxiety2.12.35.01.1-1.1-2.21.7-1.6-1.7-1.7-1.60.6
Baseline Anxiety5.96.210.2-3.23.23.0-3.12.61.71.60.7-2.1
Tail length1.85.415.73.9-4.0-1.81.7-1.01.01.12.31.6
Length with tail1.24.510.53.2-3.2-2.62.3-2.1-1.1-1.0-0.20.8
Length without tail1.43.18.20.00.0-1.41.3-1.7-2.6-2.5-2.9-0.7
Times rat made contact with spout3.43.912.71.5-1.5-2.22.0-2.0-1.5-1.5-1.03.6
Lifetime Intake0.10.10.10.4-0.4-0.10.1-0.00.20.20.4-0.2
Liver weight, left0.71.12.30.1-0.1-0.80.8-1.1-1.5-1.5-1.50.7
Liver weight, right0.81.33.21.8-1.8-1.51.3-1.0-0.5-0.4-0.00.1
Locomotor activity0.30.41.1-1.01.10.8-0.70.50.00.0-0.2-0.4
Locomotor testing distance0.91.42.3-1.51.51.5-1.31.20.70.70.5-1.4
Locomotor testing rearing0.50.71.3-0.90.91.1-1.00.90.80.80.7-0.3
Locomotion in novel chamber0.50.61.3-0.70.70.7-1.00.70.60.60.5-1.2
Locomotion in novel chamber post-restriction1.41.73.61.9-1.9-1.51.4-1.1-0.3-0.30.21.7
Fecal boli incidents, locomotor time 10.50.50.9-0.90.90.7-0.90.90.60.60.4-0.2
Change in fecal boli incidents, locomotor task1.11.02.8-0.80.80.10.5-0.7-1.3-1.4-1.70.6
Time >=10cm from walls, locomotor time 10.90.92.60.4-0.40.7-0.70.81.41.41.6-0.2
Bouts of movement, locomotor time 10.60.61.9-1.41.40.6-0.80.60.0-0.0-0.4-0.1
Total resting periods, locomotor time 10.60.62.1-1.41.40.4-0.60.4-0.3-0.3-0.70.2
Rest time, locomotor task time 10.30.40.7-0.20.2-0.70.4-0.5-0.7-0.7-0.80.7
Distance moved, locomotor task time 10.30.30.70.6-0.60.40.00.10.50.50.7-0.8
Vertical activity count, locomotor time 10.70.71.90.7-0.70.5-0.40.51.01.01.4-1.0
Time >=10cm from walls, locomotor time 20.10.10.30.1-0.10.5-0.30.30.30.30.2-0.3
Bouts of movement, locomotor time 20.80.81.6-1.21.20.6-1.21.00.60.50.1-1.0
Total resting periods, locomotor time 21.01.11.8-1.11.10.8-1.31.20.90.90.6-1.2
Rest time, locomotor task time 20.10.10.5-0.20.2-0.1-0.20.10.10.10.20.7
Distance moved, locomotor task time 20.20.31.80.1-0.00.7-0.10.10.10.1-0.0-1.3
Vertical activity count, locomotor time 21.01.13.8-0.10.11.1-0.90.91.01.00.9-2.0
Light reinforcement 10.61.13.81.0-0.90.3-0.40.61.31.42.0-0.5
Light reinforcement 20.60.82.21.5-1.5-0.40.3-0.20.60.61.2-0.3
Bone: marrow area0.40.92.0-0.30.20.9-0.81.01.31.31.4-0.5
Bone: maximum diameter0.61.12.91.7-1.7-1.11.3-0.9-0.4-0.3-0.0-0.3
Bone: maximum force2.64.511.63.4-3.3-2.52.4-1.7-1.0-0.8-0.4-0.8
Bone: maximum moment3.25.613.53.7-3.6-2.82.8-2.1-1.3-1.1-0.7-0.3
Mean time between licks in bursts1.11.52.7-1.71.71.6-1.31.20.70.60.2-1.3
Mean num. licks in bursts1.72.15.40.7-0.8-1.81.3-1.5-1.4-1.4-1.22.3
Cd content in liver1.01.22.3-1.51.51.0-1.21.10.60.50.0-1.2
Co content in liver0.10.10.2-0.50.50.2-0.40.40.30.30.30.0
Cu content in liver1.62.03.70.8-0.8-1.91.3-1.5-1.6-1.6-1.41.5
Fe content in liver0.70.91.6-1.31.21.2-1.20.90.60.60.4-0.3
K content in liver0.80.82.21.1-1.1-0.40.10.21.01.01.50.2
Mg content in liver2.02.14.7-0.20.21.1-1.21.52.02.02.2-0.9
Mn content in liver0.20.20.40.6-0.6-0.60.5-0.4-0.3-0.2-0.2-0.0
Na content in liver0.00.00.1-0.00.0-0.30.0-0.1-0.0-0.00.1-0.0
Rb content in liver0.40.51.20.9-0.80.1-0.30.40.90.91.1-0.3
Se content in liver0.20.20.50.5-0.6-0.00.0-0.10.30.30.60.7
Sr content in liver1.91.83.30.2-0.2-0.61.1-1.5-1.8-1.8-1.81.5
Zn content in liver0.00.00.1-0.10.1-0.20.1-0.0-0.1-0.1-0.10.2
Bone: minimum diameter1.63.06.82.6-2.6-2.02.1-1.7-1.0-0.8-0.30.9
Time in familiar zone, hab. session 10.30.30.70.1-0.1-0.60.4-0.5-0.7-0.7-0.80.4
Time in novel zone, hab. session 10.10.10.3-0.10.10.4-0.20.40.50.50.6-0.3
Total zone transitions, hab. session 10.40.51.1-0.80.80.7-0.70.80.60.60.3-1.1
Total locomotion distance, hab. session 10.30.51.00.00.00.5-0.50.70.80.90.9-1.0
Locomotion velocity, hab. session 10.40.51.00.00.00.6-0.60.70.90.91.0-1.0
Time in familiar zone, hab. session 20.30.30.5-0.60.60.7-0.50.60.50.50.4-0.3
Time in novel zone, hab. session 20.00.00.2-0.10.20.1-0.20.1-0.0-0.0-0.2-0.5
Total zone transitions, hab. session 22.12.73.9-0.90.91.6-1.71.92.02.01.7-1.8
Total locomotion distance, hab. session 21.82.44.70.1-0.01.3-1.31.62.12.12.2-1.5
Locomotion velocity, hab. session 21.52.04.40.3-0.31.0-1.11.41.92.02.1-1.4
Novel to familiar place preference ratio3.43.64.92.1-2.1-2.22.1-2.1-1.7-1.7-1.31.5
Novelty place preference3.53.65.12.0-2.0-2.32.0-2.1-1.8-1.7-1.41.5
Time in novel zone, NPP test2.62.74.01.8-1.8-2.01.8-1.8-1.5-1.5-1.11.3
Total zone transitions, NPP test3.44.86.4-1.31.32.2-2.32.52.52.52.3-2.3
Total locomotion distance, NPP test3.24.46.9-0.50.51.9-2.12.22.62.62.6-2.2
Locomotion velocity, NPP test2.02.84.9-0.20.21.5-1.71.72.12.12.2-1.7
Intraocular pressure0.20.30.80.9-0.9-0.30.3-0.10.40.40.60.5
Delta distance traveled before/after self-admin1.71.82.6-0.90.91.6-1.51.51.61.61.5-0.5
Delta ambulatory time before/after self-admin2.42.64.3-1.51.52.1-1.91.81.71.71.5-0.7
Parametrial fat weight0.71.43.61.9-1.9-1.21.3-1.1-0.3-0.30.30.9
Pavlov. Cond. lever latency2.32.94.0-1.31.31.8-1.82.01.91.81.5-1.8
Pavlov. Cond. magazine entry latency3.95.06.92.1-2.1-2.62.5-2.5-2.1-2.0-1.52.4
Pavlov. Cond. change in total contacts2.02.13.20.8-0.8-1.41.5-1.7-1.8-1.8-1.61.4
Pavlov. Cond. index score3.24.15.32.3-2.3-2.32.3-2.2-1.7-1.6-1.02.1
Pavlov. Cond. latency score3.24.15.22.0-2.0-2.32.3-2.3-1.8-1.8-1.22.3
Pavlov. Cond. lever contacts1.01.11.61.0-1.0-1.11.2-1.3-1.0-1.0-0.71.2
Pavlov. Cond. magazine entry number5.16.48.0-2.12.12.8-2.82.82.62.52.1-2.8
Pavlov. Cond. intertrial magazine entries0.50.61.50.3-0.30.6-0.50.71.11.11.2-0.4
Pavlov. Cond. lever-magazine prob. diff.3.44.25.62.3-2.3-2.42.4-2.3-1.7-1.7-1.12.0
Pavlov. Cond. response bias3.94.76.21.9-1.9-2.52.5-2.4-2.1-2.1-1.72.2
Pavlov. Cond. lever latency0.40.61.8-0.50.5-0.30.3-0.5-1.1-1.1-1.30.3
Pavlov. Cond. magazine entry latency2.42.73.5-1.71.71.8-1.81.91.61.61.3-1.4
Pavlov. Cond. change in total contacts0.71.01.3-0.60.61.0-0.91.11.11.11.1-0.9
Pavlov. Cond. index score0.70.91.3-0.60.60.9-0.91.11.21.11.1-0.7
Pavlov. Cond. latency score0.91.11.7-0.50.51.0-1.01.21.31.31.3-0.8
Pavlov. Cond. lever contacts0.60.82.60.7-0.70.4-0.30.61.21.31.6-0.2
Pavlov. Cond. magazine entry number2.12.53.21.5-1.5-1.71.7-1.8-1.6-1.6-1.31.6
Pavlov. Cond. intertrial magazine entries0.60.82.51.6-1.6-0.90.8-0.7-0.1-0.10.20.5
Pavlov. Cond. lever-magazine prob. diff.0.81.01.4-0.70.71.0-1.01.11.21.21.1-0.8
Pavlov. Cond. response bias0.60.81.7-0.10.00.7-0.60.91.21.21.3-0.7
Time in closed arm before self-admin0.70.81.50.1-0.1-1.00.8-0.9-1.1-1.1-1.21.0
Time in closed arm after self-admin1.21.23.1-0.30.3-0.90.8-1.0-1.5-1.5-1.80.6
Time in open arm before self-admin0.80.81.6-0.60.61.2-1.00.90.90.90.8-1.0
Time in open arm after self-admin0.70.81.0-0.60.61.0-1.01.00.90.90.9-0.8
Bone: periosteal estimation0.71.44.22.0-2.0-1.21.3-0.8-0.2-0.10.3-0.4
Bone: periosteal perimeter2.94.87.42.7-2.6-2.62.7-2.3-1.9-1.8-1.31.2
Bone: post-yield work0.50.61.3-0.30.30.6-0.80.90.90.90.8-1.1
Progressive ratio test 1 active lever presses0.40.41.11.1-1.1-0.50.5-0.30.30.30.70.3
Progressive ratio test 1 breakpoint0.60.61.61.3-1.3-0.70.6-0.50.20.20.70.5
Progressive ratio test 1 inactive lever presses0.80.82.61.6-1.6-0.90.8-0.50.20.30.7-0.1
Progressive ratio test 2 active lever presses0.20.20.50.7-0.7-0.40.4-0.4-0.0-0.00.20.6
Progressive ratio test 2 breakpoint0.20.20.50.7-0.7-0.20.2-0.10.30.40.50.4
Progressive ratio test 2 inactive lever presses0.30.40.60.8-0.8-0.70.7-0.6-0.4-0.4-0.30.2
Incentive Sensitization - Responses0.20.21.20.6-0.6-0.40.4-0.3-0.00.00.11.1
Incentive Sensitization - Breakpoint0.20.21.30.5-0.5-0.40.4-0.3-0.1-0.1-0.01.1
Sum of active levers in priming session hrs 5-61.81.72.31.1-1.1-1.51.5-1.5-1.3-1.3-1.11.2
Progressive ratio0.20.20.6-0.80.80.4-0.50.40.00.0-0.3-0.4
Food seeking constrained by brief footshock0.40.50.9-0.20.2-0.80.4-0.6-0.8-0.8-0.81.0
Seeking ratio, punishment vs. effort0.10.10.20.4-0.4-0.40.2-0.20.10.10.30.4
Retroperitoneal fat weight1.65.215.13.9-3.9-2.22.0-1.8-0.2-0.01.31.7
Reaction time number correct4.86.911.2-0.70.72.6-2.42.83.33.33.3-2.7
Reaction time mean minus median0.40.51.4-0.10.1-0.50.4-0.7-0.9-0.9-0.81.2
Reaction time mean minus median AUC0.00.10.10.0-0.0-0.20.3-0.3-0.3-0.3-0.20.4
Reaction time num false alarms0.10.10.3-0.50.50.4-0.40.30.10.1-0.00.5
Reaction time num false alarms AUC0.40.51.1-1.01.01.0-0.90.70.40.40.20.1
Reaction time trials correct on left4.86.911.2-0.70.72.6-2.42.83.33.33.3-2.7
Reaction time trials on left5.07.211.7-0.70.72.7-2.52.93.43.43.4-2.8
Reaction time mean0.10.10.40.5-0.5-0.10.3-0.20.10.10.40.6
Reaction time mean AUC0.20.20.80.3-0.30.4-0.20.30.60.70.90.1
Median of all reaction times0.10.10.40.5-0.50.10.10.10.40.50.60.2
Reaction time omissions0.20.30.90.0-0.00.7-0.60.40.70.70.90.0
Reaction time false alarm rate0.71.02.3-0.60.5-0.50.4-0.8-1.3-1.3-1.51.5
Reaction time premature initiation rate0.40.61.7-1.31.30.9-0.80.60.10.1-0.40.1
Reaction time premature initiations2.23.14.9-1.51.52.2-2.02.01.91.81.5-1.3
Std. dev. reaction times0.10.20.4-0.70.70.6-0.50.40.20.20.20.4
Reaction time trials completed5.07.211.7-0.70.72.7-2.52.93.43.43.4-2.8
Reaction time trials AUC4.97.011.5-0.60.72.6-2.42.83.33.43.4-2.7
Run reversals in cocaine runway, females1.11.11.7-0.90.91.2-1.31.21.11.11.0-0.4
Run reversals in cocaine runway, males2.72.64.01.4-1.5-1.71.8-1.8-1.5-1.5-1.12.0
Latency to leave start box in cocaine runway0.50.50.9-0.60.61.0-0.70.80.70.70.6-0.4
Latency to leave start box in cocaine runway, F1.71.92.9-0.90.91.7-1.41.51.61.61.4-1.0
Latency to leave start box in cocaine runway, M0.20.20.30.4-0.4-0.50.6-0.5-0.4-0.4-0.40.5
Std. dev. time between licks in bursts2.93.56.70.1-0.01.5-1.51.82.42.42.6-2.2
Total sessions with >9 infusions0.40.51.5-0.60.60.7-0.70.60.50.50.3-1.2
Short access day 1 total inactive lever presses1.11.32.0-0.50.51.1-1.21.21.31.31.2-1.4
Short access day 10 total inactive lever presses2.32.55.12.2-2.2-2.31.9-1.5-0.8-0.8-0.40.9
Short access day 1 total infusions0.80.92.1-1.41.41.0-1.00.80.20.2-0.2-1.1
Short access day 10 total infusions0.50.50.80.9-0.9-0.90.9-0.8-0.4-0.4-0.10.7
Short access total infusions0.00.00.00.0-0.0-0.1-0.00.00.00.00.1-0.1
Short access day 1 locomotion0.20.20.5-0.50.60.30.0-0.1-0.5-0.5-0.7-0.4
Short access day 10 total locomotion0.50.61.50.0-0.0-0.70.7-0.8-1.1-1.1-1.20.1
Short access total locomotion0.20.20.7-0.50.5-0.10.1-0.2-0.6-0.6-0.9-0.4
One hour access (0.3 mA shock)0.50.61.71.3-1.3-0.60.5-0.30.40.40.80.5
Compulsive drug intake0.10.10.40.6-0.6-0.40.2-0.10.20.20.4-0.2
One hour access (shock baseline)0.20.20.70.3-0.30.3-0.30.30.70.70.8-0.3
Social response proportion0.70.82.5-0.80.80.9-0.70.90.60.60.3-1.6
Social responses0.60.83.9-0.60.60.8-0.70.80.60.60.4-2.0
Social time0.40.52.0-0.50.50.8-0.70.80.60.60.3-1.4
Soleus weight0.51.33.82.0-2.0-1.11.1-0.70.10.20.80.9
Bone: stiffness0.50.83.81.1-1.1-0.70.6-0.2-0.1-0.1-0.2-2.0
Tibialis anterior weight0.20.51.4-0.00.00.5-0.50.81.11.11.2-0.1
Time to tail flick, vehicle, before self-admin0.10.10.30.2-0.2-0.2-0.10.10.30.30.50.6
Time to tail flick, vehicle, after self-admin1.51.63.0-1.71.71.5-1.41.30.60.60.1-1.4
Time to tail flick, test, before self-admin0.30.30.70.4-0.4-0.80.6-0.6-0.4-0.4-0.50.4
Time to tail flick, test, after self-admin0.20.20.8-0.60.70.3-0.30.3-0.0-0.0-0.2-0.9
Delta time to tail flick, vehicle, before/after SA1.01.01.7-0.90.91.3-1.11.10.90.90.7-1.2
Delta time to tail flick, test, before/after SA0.30.30.5-0.70.70.4-0.10.0-0.5-0.5-0.7-0.7
Tibia length6.819.333.75.8-5.7-5.45.2-4.5-3.3-3.1-2.22.0
Ambulatory time before self-admin2.93.05.01.9-1.9-2.22.1-1.9-1.5-1.4-0.91.3
Ambulatory time after self-admin0.20.20.50.5-0.5-0.20.2-0.10.30.30.70.7
Bone: tissue strength0.50.50.90.9-0.9-0.10.10.20.60.70.8-0.9
Total heroin consumption1.21.42.60.4-0.3-1.21.1-1.2-1.6-1.6-1.6-0.3
Bone: trabecular number0.00.00.10.0-0.00.0-0.20.10.20.20.30.3
Bone: trabecular spacing2.22.95.0-0.20.21.5-1.51.72.22.22.2-1.9
Bone: trabecular thickness2.63.14.11.1-1.1-1.91.8-2.0-2.0-2.0-1.91.8
Bone: trabecular tissue density0.40.51.3-1.11.10.8-0.70.60.20.1-0.2-0.8
Water consumed over 24 hours0.70.82.00.0-0.1-1.20.9-0.8-0.9-1.0-0.91.4
Number of responses in last shaping day0.30.31.40.8-0.7-0.30.2-0.10.10.20.3-1.2