Hub : Genes

Dcakd

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Dcakd 0.16 0.06 0.0e+00 0.22 0.21 0.23 0.15 1.8e-23 1.4e-22 1.3e-24 1.5e-16
2 Adipose gene expression Dcakd 0.08 0.04 4.3e-09 0.07 0.07 0.05 0.07 4.2e-08 1.0e-08 3.3e-06 1.0e-08
3 LHb mRNA stability Dcakd 0.29 0.14 1.6e-04 0.1 0.13 0.16 0.11 2.3e-03 4.7e-04 1.4e-04 1.3e-03
4 pVTA gene expression Dcakd 0.14 0.06 8.6e-13 0.15 0.17 0.14 0.16 4.0e-12 2.1e-13 1.3e-11 5.7e-13
5 NAcc gene expression Dcakd 0.07 0.04 3.2e-10 0.08 0.07 0.07 0.08 1.9e-12 8.6e-11 3.1e-10 6.1e-12
6 BLA gene expression Dcakd 0.26 0.09 1.9e-13 0.2 0.22 0.16 0.2 1.4e-10 7.5e-12 4.6e-09 7.4e-11
7 LHb gene expression Dcakd 0.24 0.11 3.7e-04 0.03 0.1 0.06 0.06 6.0e-02 2.3e-03 2.0e-02 2.0e-02
8 Brain gene expression Dcakd 0.15 0.07 6.6e-12 0.12 0.12 0.1 0.12 6.1e-11 3.8e-11 7.9e-10 3.8e-11
9 IL gene expression Dcakd 0.2 0.1 9.1e-04 0.2 0.04 0.13 0.01 1.1e-05 3.3e-02 6.4e-04 1.9e-01
10 Liver gene expression Dcakd 0.07 0.03 2.3e-09 0.08 0.06 0.06 0.07 6.9e-09 9.9e-08 4.0e-07 5.2e-08
11 pVTA intron excision ratio chr10_88463980_88480049 0.07 0.04 1.8e-04 0.06 0.06 0.04 0.05 1.8e-05 3.1e-05 1.4e-04 6.2e-05
12 PL mRNA stability Dcakd 0.07 0.03 9.1e-08 0.06 0.08 0.06 0.07 2.9e-07 1.2e-08 1.2e-07 9.3e-08
13 Liver mRNA stability Dcakd 0.07 0.04 2.2e-06 0.04 0.04 0.05 0.04 2.2e-05 1.2e-05 7.5e-06 1.4e-05
14 pVTA mRNA stability Dcakd 0.09 0.05 1.6e-06 0.09 0.06 0.07 0.07 2.4e-07 2.6e-05 3.3e-06 2.3e-06
15 NAcc mRNA stability Dcakd 0.03 0.02 2.7e-04 0.03 0.02 0.02 0.02 7.5e-05 7.2e-04 2.0e-04 4.8e-04
16 Eye gene expression Dcakd 0.45 0.21 7.1e-03 0.06 0.02 0.04 0.06 4.2e-02 1.6e-01 8.1e-02 4.6e-02
17 Brain mRNA stability Dcakd 0.12 0.07 6.6e-05 0.03 0.05 0.04 0.04 1.1e-03 2.6e-05 1.9e-04 1.5e-04
18 pVTA isoform ratio NM_001007724.1 0.1 0.06 8.7e-04 0.01 0.04 0.03 0.04 6.6e-02 7.9e-04 3.1e-03 6.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density2.03.46.1-1.9-1.4-2.3-1.9-1.9-2.4-2.5-2.0-1.9-1.90.2-1.6-2.0-1.9-1.9-2.0-1.1-0.8
Area under the delay curve0.10.10.2-0.0-0.30.20.10.10.30.30.30.00.00.30.00.30.40.30.20.40.4
BMI with tail1.13.99.70.41.4-0.11.70.91.11.61.41.51.52.33.12.92.82.92.42.90.9
BMI without tail0.72.09.0-1.1-0.1-1.60.2-0.4-0.40.00.0-0.5-0.53.01.81.91.82.00.82.61.1
Body weight1.14.621.1-2.0-0.5-2.1-0.3-1.6-1.3-0.5-1.0-1.3-1.34.62.32.12.22.21.84.31.9
Weight adjusted by age0.20.32.2-0.3-0.90.5-0.3-0.50.10.3-0.2-0.1-0.10.7-0.20.20.20.20.51.11.5
Bone surface4.37.813.5-3.7-3.0-3.3-3.3-3.5-3.5-3.3-3.5-2.9-2.91.7-2.4-2.5-2.5-2.4-2.2-0.20.7
Bone volume3.05.48.9-2.9-2.3-3.0-2.7-2.7-3.0-3.0-2.8-2.3-2.31.1-2.0-2.1-2.1-2.1-2.3-0.50.0
Breakpoint value in progressive ratio session0.60.71.9-0.8-1.3-0.4-1.1-1.0-0.5-0.5-1.0-0.9-0.90.3-1.4-0.7-0.7-0.7-0.9-0.50.9
Number of licking bursts0.60.93.10.60.60.60.5-0.20.50.90.2-0.2-0.21.41.11.01.21.11.81.41.3
Context. condit. distance diff. score2.12.53.81.71.41.51.81.81.71.71.71.31.3-0.11.91.81.91.92.01.30.2
Locomotion velocity, session 10.20.21.1-0.3-0.3-0.4-0.3-0.1-0.4-0.6-0.30.30.3-0.7-0.4-0.6-0.6-0.7-1.1-0.4-0.4
Locomotion distance, session 10.10.10.5-0.10.1-0.10.10.4-0.0-0.20.10.70.7-0.70.0-0.2-0.1-0.3-0.4-0.4-0.4
Locomotion velocity, session 20.70.84.10.2-0.20.4-0.20.6-0.2-0.60.00.20.2-2.0-0.9-1.1-1.1-1.2-1.5-1.3-1.2
Locomotion distance, session 20.20.31.4-0.3-0.1-0.1-0.20.3-0.3-0.5-0.30.40.4-1.2-0.5-0.7-0.8-0.7-0.8-0.8-0.6
Locomotion velocity, session 30.00.00.1-0.10.3-0.10.1-0.1-0.3-0.3-0.30.20.2-0.10.4-0.10.0-0.10.1-0.0-0.3
Locomotion distance, session 30.20.20.90.10.10.40.3-0.00.20.3-0.1-0.2-0.20.50.50.50.60.41.00.70.8
Stereotopy head waving bouts, day 30.60.72.90.50.80.40.60.70.40.10.91.21.2-1.20.2-0.2-0.2-0.1-0.5-1.3-1.7
Stereotopy head waving duration, day 30.60.72.00.70.70.80.70.80.80.41.01.41.4-1.20.20.10.10.2-0.1-0.9-1.2
Locomotion velocity, session 70.90.92.51.21.60.81.31.20.90.70.81.11.1-0.71.10.70.70.80.4-0.3-1.3
Locomotion distance, session 70.40.51.20.90.71.00.91.10.80.60.70.80.8-0.60.70.60.60.70.50.2-0.2
Stereotopy head waving bouts, day 70.60.72.1-0.00.20.3-0.6-0.5-0.5-0.5-0.8-0.4-0.4-1.0-0.9-1.3-1.3-1.3-0.2-1.4-1.1
Stereotopy head waving duration, day 70.70.83.20.70.71.0-0.1-0.00.1-0.0-0.30.20.2-1.6-0.7-1.2-1.1-1.3-0.0-1.8-1.5
Locomotion velocity, session 80.70.92.80.31.2-0.31.10.80.50.60.81.41.40.21.71.11.01.10.40.6-0.5
Locomotion distance, session 80.71.02.61.10.91.11.11.61.10.91.11.31.3-1.10.80.70.70.70.70.0-0.4
Degree of sensitization distance0.20.20.50.10.00.00.30.50.20.20.60.50.50.10.50.60.40.6-0.00.7-0.1
Degree of sensitization stereotypy0.40.51.20.30.30.7-0.4-0.4-0.3-0.2-0.8-0.4-0.4-0.9-0.7-1.0-1.0-1.10.3-1.0-0.8
Conditioned locomotion0.00.00.10.10.10.00.10.1-0.1-0.10.0-0.2-0.20.00.10.10.10.1-0.0-0.1-0.3
Cocaine response after cond. corrected0.10.20.5-0.10.2-0.3-0.1-0.2-0.6-0.5-0.2-0.7-0.70.20.4-0.00.00.10.40.5-0.7
Cocaine response after cond. not corrected0.60.71.6-0.4-0.1-0.7-0.7-0.6-1.3-1.2-0.8-1.2-1.2-0.1-0.3-0.9-0.9-0.9-0.4-0.0-1.2
Cocaine response before conditioning0.70.92.2-0.5-0.4-0.4-0.8-0.6-0.9-0.9-1.0-0.2-0.2-0.6-1.1-1.4-1.4-1.5-1.4-1.1-0.6
Saline control response0.30.40.9-0.9-0.6-1.0-0.5-0.6-0.5-0.4-0.6-0.9-0.90.9-0.30.00.0-0.1-0.20.10.6
Bone: connectivity density3.35.17.8-2.4-2.3-2.3-2.6-2.5-2.8-2.8-2.5-2.4-2.40.4-2.4-2.5-2.4-2.4-2.2-1.0-0.0
Bone: cortical apparent density2.63.614.32.32.02.01.42.31.71.01.61.61.6-3.8-0.3-0.7-0.6-0.6-0.4-3.2-2.6
Bone: cortical area2.13.25.7-2.3-1.5-2.4-2.0-2.0-2.2-2.4-2.1-1.7-1.70.5-1.5-1.9-1.8-1.8-1.4-0.6-0.5
Bone: cortical porosity9.310.118.7-4.3-3.9-3.9-3.7-4.0-3.9-3.6-3.7-3.6-3.62.7-2.3-2.1-2.0-2.1-2.11.21.7
Bone: cortical porosity5.66.112.8-3.6-2.8-3.5-2.7-3.2-3.2-2.8-2.7-2.7-2.72.7-1.1-1.1-1.1-1.1-1.41.71.3
Bone: cortical thickness0.81.37.50.41.1-0.3-0.10.2-0.5-1.0-0.3-0.4-0.4-1.8-0.4-1.4-1.3-1.3-0.4-1.9-2.7
Bone: cortical thickness1.61.94.3-0.1-0.2-0.0-1.0-0.6-1.0-1.4-1.3-1.3-1.3-1.5-1.7-2.0-2.1-2.0-1.0-2.0-1.7
Bone: cortical tissue density2.63.514.12.31.92.01.42.31.71.01.51.61.6-3.8-0.4-0.7-0.6-0.7-0.4-3.2-2.5
Condit. Reinf. active minus inactive responses1.11.23.5-1.3-1.9-0.7-1.4-1.1-0.9-0.8-1.2-1.5-1.50.8-1.4-0.6-0.7-0.6-0.60.41.5
Condit. Reinf. active-inactive response ratio0.40.42.1-0.4-1.30.5-0.7-0.4-0.1-0.1-0.5-0.5-0.50.2-0.9-0.2-0.3-0.30.10.61.4
Condit. Reinf. active responses1.11.33.1-1.5-1.7-1.2-1.4-1.0-1.1-1.2-1.2-1.4-1.40.5-1.4-0.8-0.9-0.8-1.2-0.10.9
Condit. Reinf. inactive responses0.70.92.8-1.1-0.3-1.7-0.7-0.4-1.1-1.3-0.6-0.6-0.6-0.1-0.6-0.8-0.8-0.8-1.5-1.1-1.1
Incentive salience index mean1.41.73.4-1.4-1.9-1.1-1.6-1.3-1.2-1.1-1.5-1.7-1.70.6-1.7-1.1-1.1-1.1-1.0-0.11.1
Condit. Reinf. lever presses0.60.81.5-0.9-0.6-1.2-0.9-0.6-0.9-0.9-0.9-1.0-1.0-0.3-1.0-1.0-1.0-1.0-1.2-0.9-0.2
Condit. Reinf. active minus inactive responses4.45.710.4-2.8-3.2-2.2-2.9-2.4-2.7-2.8-2.6-2.5-2.50.4-2.8-2.3-2.4-2.2-2.7-0.40.3
Condit. Reinf. active-inactive response ratio3.84.48.4-2.4-2.9-1.7-2.6-2.3-2.3-2.1-2.3-2.5-2.50.7-2.4-2.0-2.0-1.8-2.0-0.11.0
Condit. Reinf. active responses4.66.412.1-2.9-3.5-2.3-3.1-2.5-2.8-2.9-2.8-2.4-2.40.2-3.1-2.5-2.6-2.5-2.8-0.60.4
Condit. Reinf. inactive responses1.01.33.5-0.9-1.0-1.0-1.1-0.6-1.0-1.3-1.0-0.2-0.2-0.9-1.5-1.4-1.4-1.5-1.9-1.3-0.7
Condit. Reinf. lever presses1.62.24.6-1.6-2.1-1.1-1.9-1.2-1.5-1.7-1.5-1.3-1.3-0.2-2.2-1.6-1.6-1.6-1.7-0.70.2
Condit. Reinf. lever reinforcers received3.95.410.3-2.6-3.2-2.1-2.8-2.2-2.5-2.7-2.6-2.2-2.20.1-3.0-2.3-2.4-2.3-2.8-0.70.2
Conditioned reinforcement - actives0.10.10.4-0.3-0.3-0.1-0.2-0.4-0.0-0.0-0.2-0.3-0.30.6-0.10.30.30.30.30.30.5
Conditioned reinforcement - inactives0.71.14.3-1.7-0.7-2.1-1.0-1.2-1.4-1.2-1.1-1.1-1.11.1-0.3-0.4-0.4-0.3-0.40.20.4
Conditioned locomotion0.81.03.9-1.1-1.3-0.7-0.8-1.2-0.6-0.4-0.8-1.0-1.02.0-0.30.50.40.50.51.51.6
Patch foraging indifference point 0 sec1.12.04.6-1.4-0.9-1.5-1.3-0.8-1.7-2.1-1.4-1.1-1.1-0.5-1.3-1.4-1.6-1.2-2.0-1.4-1.6
Patch foraging indifference point AUC0.30.51.6-0.6-0.6-0.1-0.5-0.6-0.5-0.3-0.4-1.1-1.10.7-0.0-0.10.3-0.21.11.30.9
Delay disc. indifference point, 0s delay0.10.10.40.2-0.40.7-0.00.20.40.20.30.30.3-0.6-0.4-0.1-0.0-0.3-0.2-0.10.3
Delay disc. indifference point, 16s delay0.60.61.80.30.20.40.60.30.70.80.70.40.40.70.91.11.11.11.01.30.9
Delay disc. indifference point, 2s delay1.21.42.7-1.4-1.7-1.1-1.4-1.1-1.2-1.3-1.0-0.9-0.90.0-1.5-1.2-1.1-1.3-1.6-0.50.1
Delay disc. indifference point, 24s delay0.20.20.8-0.3-0.60.2-0.3-0.3-0.1-0.0-0.2-0.5-0.50.6-0.00.20.20.20.50.90.9
Delay disc. indifference point, 4s delay0.10.10.20.1-0.40.30.10.30.40.30.40.20.20.0-0.20.20.30.3-0.10.10.4
Delay disc. indifference point, 8s delay0.10.10.40.20.20.20.20.40.30.20.30.20.2-0.4-0.2-0.1-0.2-0.0-0.2-0.6-0.5
Indifference point function ln k0.71.23.2-1.0-0.9-1.1-1.1-1.2-1.1-1.2-1.3-0.6-0.60.1-1.2-1.2-1.5-1.0-1.8-1.0-0.7
Indifference point function log k0.71.23.2-1.0-0.9-1.1-1.1-1.2-1.1-1.2-1.3-0.6-0.60.1-1.2-1.2-1.5-1.0-1.8-1.0-0.7
Patch foraging total patch changes 0 sec1.22.35.2-1.7-1.0-1.8-1.4-1.0-1.9-2.3-1.5-1.2-1.2-0.3-1.3-1.5-1.6-1.3-2.1-1.3-1.6
Patch foraging total patch changes 12 sec1.41.83.6-1.5-1.3-1.4-1.5-0.8-1.6-1.9-1.2-1.0-1.0-0.7-1.6-1.7-1.4-1.6-1.7-1.1-0.6
Patch foraging total patch changes 18 sec0.20.41.0-1.0-0.9-0.4-0.8-0.5-0.8-0.9-0.7-0.6-0.60.2-0.5-0.4-0.2-0.5-0.20.30.2
Patch foraging total patch changes 24 sec1.11.83.8-1.5-0.9-1.5-1.3-1.1-1.7-2.0-1.4-0.9-0.9-0.2-1.3-1.5-1.5-1.5-1.7-1.4-1.1
Patch foraging total patch changes 6 sec0.50.82.0-1.0-0.8-0.8-1.0-0.6-1.2-1.4-1.1-1.4-1.4-0.1-0.8-0.8-0.7-0.7-0.7-0.2-0.4
Patch foraging time to switch 0 sec0.10.20.70.60.10.50.50.80.60.40.80.10.1-0.60.20.40.50.3-0.00.10.5
Patch foraging water rate 0 sec0.10.10.5-0.50.1-0.5-0.1-0.3-0.4-0.4-0.50.00.00.40.30.0-0.20.10.00.1-0.7
Patch foraging water rate 12 sec0.00.10.30.40.20.50.2-0.00.20.2-0.0-0.1-0.10.30.30.10.10.10.50.4-0.1
Patch foraging water rate 18 sec0.61.06.30.10.7-0.40.00.1-0.7-0.9-0.10.30.3-1.0-0.2-1.0-1.3-0.8-1.5-1.7-2.5
Patch foraging water rate 24 sec0.50.62.50.70.60.50.51.00.50.10.60.70.7-1.6-0.1-0.2-0.50.1-0.8-1.2-1.6
Patch foraging water rate 6 sec0.71.02.0-1.0-0.8-0.8-1.1-1.2-1.3-1.2-1.4-0.8-0.80.5-0.9-1.0-1.3-1.0-1.1-0.5-0.4
Seeking ratio, delayed vs. immediate footshock1.41.77.1-0.1-0.30.20.50.20.60.80.70.00.01.71.31.91.82.01.52.71.9
Distance traveled before self-admin0.30.41.3-0.6-1.1-0.1-0.7-0.5-0.3-0.5-0.5-0.5-0.50.0-1.1-0.6-0.6-0.6-0.9-0.30.5
Distance traveled after self-admin0.10.10.30.2-0.20.40.20.50.60.30.50.30.3-0.3-0.10.30.20.20.10.20.3
Extensor digitorum longus weight4.417.228.53.73.03.74.33.44.75.14.13.53.51.44.65.35.35.35.04.12.3
Bone: elastic displacement0.50.61.2-0.2-0.3-0.3-0.8-1.1-0.9-0.9-0.9-1.1-1.10.1-0.7-1.0-0.9-0.9-0.3-0.4-0.5
Bone: elastic work1.92.44.9-1.5-1.2-1.8-1.7-1.8-2.0-2.0-1.9-2.2-2.20.6-1.4-1.4-1.4-1.3-1.1-0.4-0.5
Bone: endosteal estimation2.75.815.7-3.7-4.0-2.7-2.7-2.8-2.2-1.9-2.4-1.8-1.83.1-1.6-0.5-0.5-0.4-1.62.33.5
Bone: endosteal perimeter4.08.419.3-4.3-4.2-3.5-3.2-3.8-2.8-2.2-2.8-2.5-2.54.4-1.5-0.5-0.6-0.4-1.22.64.0
Epididymis fat weight0.10.31.0-0.30.3-0.20.3-0.2-0.00.30.00.40.40.91.00.70.80.60.51.00.7
Delta time in closed arm before/after self-admin3.33.07.81.92.80.12.22.11.51.42.12.02.0-0.92.31.51.51.51.1-0.3-1.9
Delta time in open arm before/after self-admin0.20.21.0-0.4-0.80.3-0.6-0.50.20.2-0.50.10.10.1-1.0-0.3-0.3-0.3-0.1-0.31.0
Diff in mean of infusions in LGA sessions0.30.40.9-0.6-0.8-0.3-0.8-0.8-0.5-0.5-0.7-0.8-0.80.3-0.9-0.6-0.7-0.6-0.4-0.20.6
Delay discount exponential model param0.10.10.20.20.4-0.0-0.0-0.0-0.2-0.2-0.20.10.1-0.4-0.0-0.4-0.4-0.4-0.2-0.5-0.5
Extinction: sum of active levers before priming0.10.10.30.10.0-0.20.10.10.20.10.2-0.4-0.40.5-0.10.30.30.2-0.1-0.3-0.3
Active lever presses in extinction session 62.42.44.8-1.9-2.0-1.5-1.7-2.1-1.4-1.1-1.7-2.1-2.12.2-1.0-0.4-0.4-0.5-0.21.11.9
Bone: final force1.52.44.7-1.7-0.7-1.9-1.5-1.1-1.8-2.2-1.8-1.2-1.2-0.7-1.3-1.9-1.9-1.9-1.7-1.3-1.2
Bone: final moment1.82.95.7-1.8-0.9-1.9-1.6-1.2-2.0-2.4-1.9-1.2-1.2-0.8-1.5-2.1-2.1-2.1-2.0-1.5-1.5
Food consumed during 24 hour testing period0.30.41.7-0.00.3-0.80.1-0.5-0.10.2-0.3-0.2-0.21.30.70.50.60.60.51.10.9
Glucose1.32.13.51.51.51.31.71.61.61.61.71.91.9-0.61.61.41.41.41.00.5-0.3
Heart weight1.42.110.3-0.50.6-1.20.5-0.9-0.20.5-0.0-0.4-0.43.22.01.71.71.82.02.41.3
Delay discount hyperbolic model param0.10.10.30.30.50.10.20.1-0.1-0.1-0.10.20.2-0.40.1-0.2-0.2-0.20.0-0.4-0.5
Intermittent access intake day 1-15 change0.91.93.61.01.40.21.61.51.31.31.61.81.8-0.11.91.61.61.90.70.7-0.7
Intermittent access intake escalation0.81.73.10.91.2-0.11.51.41.11.11.61.81.8-0.21.71.51.51.80.30.5-1.0
Intermittent access intake escalation 20.91.02.70.20.9-0.61.10.90.60.71.11.41.40.61.51.31.21.60.10.6-0.5
Intermitt. access day 1 inactive lever presses0.83.06.9-2.5-1.5-2.6-2.0-2.6-1.9-1.5-2.3-1.8-1.82.5-1.0-0.9-0.9-0.8-0.30.31.2
Intermitt. access day 15 inactive lever presses2.24.48.2-2.6-2.9-2.0-2.9-2.4-2.1-2.1-2.6-1.3-1.30.5-2.7-2.3-2.3-2.1-1.7-0.51.4
Intermitt. access escalation Index0.40.61.50.40.41.10.50.10.91.10.31.01.00.70.70.70.80.71.20.61.0
Intermittent access day 1 total infusions0.20.32.2-0.5-0.8-0.0-0.4-0.60.00.1-0.4-0.2-0.21.0-0.30.50.50.30.30.81.5
Intermittent access day 15 total infusions0.61.02.8-0.0-0.0-0.40.70.50.80.80.80.90.90.91.01.71.61.70.61.40.7
Intermittent access terminal intake (last 3 days)0.50.62.4-0.8-0.9-0.4-0.2-0.40.20.2-0.00.40.41.40.21.01.01.00.21.41.5
Intermittent access total infusions0.81.03.5-0.4-0.5-0.20.1-0.40.40.60.10.00.01.60.71.51.51.41.01.91.6
Intermittent access day 1 locomotion0.70.92.5-1.2-1.1-0.6-0.8-1.0-0.6-0.6-0.7-1.3-1.31.4-0.20.40.30.20.71.61.4
Intermittent access day 15 total locomotion0.30.62.8-0.00.0-0.50.40.40.40.30.70.20.20.50.91.31.21.30.91.70.4
Intermittent access total locomotion0.81.04.4-1.2-1.2-0.9-0.7-0.8-0.6-0.5-0.5-1.0-1.01.50.10.70.60.60.62.11.4
Intermittent access standard deviation0.10.21.2-0.30.5-1.10.20.1-0.0-0.00.20.40.4-0.10.40.20.20.3-0.3-0.4-0.5
Left kidney weight0.00.21.3-0.00.7-0.10.3-0.1-0.5-0.2-0.20.10.10.61.10.40.50.30.50.9-0.3
Right kidney weight0.20.93.9-0.30.4-0.20.2-0.6-0.6-0.1-0.2-0.6-0.61.91.40.91.11.01.32.00.6
Cocaine induced anxiety0.30.42.10.71.4-0.10.70.40.00.20.30.10.1-0.60.9-0.00.0-0.10.5-0.6-1.5
Post-drug Anxiety0.40.41.4-0.30.4-0.9-0.1-0.6-0.9-0.6-0.5-1.2-1.20.50.4-0.2-0.2-0.20.30.1-0.7
Baseline Anxiety1.72.04.7-1.8-2.2-0.8-1.7-1.7-1.2-1.1-1.5-1.6-1.61.7-1.2-0.4-0.4-0.4-0.21.42.2
Tail length1.35.19.8-2.5-2.1-2.7-2.5-2.6-3.0-2.7-2.7-3.1-3.11.7-1.7-1.6-1.7-1.5-2.10.20.3
Length with tail0.83.610.3-2.4-1.5-2.3-1.6-2.4-2.4-1.9-2.2-2.4-2.43.20.20.10.20.1-0.12.41.0
Length without tail0.51.67.9-0.20.40.20.5-0.4-0.10.3-0.00.00.02.01.91.51.71.51.92.80.8
Times rat made contact with spout0.10.10.60.20.8-0.70.1-0.4-0.3-0.1-0.4-0.4-0.40.50.50.00.00.00.30.0-0.2
Lifetime Intake0.70.93.2-0.9-0.9-0.6-0.4-0.9-0.10.1-0.4-0.4-0.41.80.21.01.01.00.61.61.7
Liver weight, left1.01.63.6-1.9-1.3-1.4-1.4-1.8-1.8-1.5-1.5-1.3-1.31.5-0.2-0.6-0.5-0.6-0.41.30.3
Liver weight, right0.20.42.3-0.10.6-0.0-0.3-0.5-0.7-0.7-0.7-0.3-0.3-0.60.0-0.9-0.9-1.0-0.0-0.4-1.5
Locomotor activity1.62.54.3-2.1-1.9-1.7-1.9-1.9-1.9-1.8-2.0-1.6-1.60.8-1.7-1.3-1.5-1.0-1.6-0.30.3
Locomotor testing distance1.83.26.5-2.4-2.6-1.9-2.1-1.9-1.9-1.9-2.0-2.0-2.00.9-2.0-1.2-1.5-1.1-2.0-0.40.8
Locomotor testing rearing0.71.44.5-1.5-2.1-0.9-1.5-1.0-1.0-1.2-1.0-1.3-1.30.1-1.7-0.7-0.9-0.7-1.4-0.20.8
Locomotion in novel chamber0.91.14.6-1.0-2.20.4-1.3-0.8-0.9-1.0-0.8-0.8-0.8-0.0-1.3-0.9-1.0-0.9-0.91.01.6
Locomotion in novel chamber post-restriction0.20.41.7-1.0-0.4-1.3-0.5-0.6-0.8-0.8-0.5-0.7-0.70.5-0.1-0.3-0.3-0.1-0.70.2-0.2
Fecal boli incidents, locomotor time 10.10.10.80.30.5-0.10.20.40.0-0.00.30.30.3-0.30.1-0.2-0.2-0.1-0.2-0.7-0.9
Change in fecal boli incidents, locomotor task0.20.20.7-0.4-0.3-0.2-0.3-0.4-0.4-0.4-0.3-0.8-0.80.6-0.10.10.00.10.00.40.3
Time >=10cm from walls, locomotor time 10.30.32.10.80.11.50.30.40.70.70.30.30.3-0.40.00.10.1-0.10.70.40.9
Bouts of movement, locomotor time 10.70.81.81.31.21.01.01.01.11.10.91.21.2-0.60.80.60.50.40.9-0.2-0.1
Total resting periods, locomotor time 10.70.81.81.31.30.81.00.91.01.10.81.01.0-0.41.00.60.60.51.10.0-0.0
Rest time, locomotor task time 10.10.10.30.40.30.60.10.10.30.2-0.00.30.3-0.4-0.2-0.3-0.4-0.20.1-0.50.1
Distance moved, locomotor task time 10.40.62.7-0.6-0.7-0.5-0.1-0.5-0.10.0-0.1-0.5-0.51.50.50.80.80.70.51.61.2
Vertical activity count, locomotor time 10.20.41.9-0.3-0.6-0.10.0-0.30.10.20.2-0.1-0.11.00.40.70.70.70.41.41.2
Time >=10cm from walls, locomotor time 20.30.40.7-0.7-0.8-0.6-0.8-0.8-0.7-0.7-0.9-0.6-0.60.2-0.7-0.7-0.7-0.7-0.20.10.5
Bouts of movement, locomotor time 20.20.30.5-0.4-0.3-0.6-0.5-0.5-0.6-0.6-0.5-0.6-0.6-0.2-0.6-0.6-0.7-0.7-0.6-0.6-0.2
Total resting periods, locomotor time 20.00.10.3-0.10.1-0.2-0.1-0.2-0.2-0.2-0.1-0.2-0.2-0.3-0.2-0.3-0.4-0.4-0.2-0.5-0.3
Rest time, locomotor task time 20.60.81.70.91.20.81.00.51.01.10.70.80.80.31.11.01.00.91.30.50.3
Distance moved, locomotor task time 20.10.10.5-0.4-0.7-0.3-0.3-0.3-0.2-0.2-0.2-0.1-0.10.3-0.20.10.0-0.1-0.30.50.4
Vertical activity count, locomotor time 20.40.51.3-0.8-1.1-0.7-0.9-0.7-0.5-0.7-0.6-0.5-0.5-0.1-1.1-0.7-0.8-0.7-0.9-0.30.1
Light reinforcement 10.71.82.7-1.4-1.0-1.6-1.4-1.3-1.5-1.6-1.5-1.2-1.20.1-1.5-1.6-1.5-1.5-1.5-1.3-0.7
Light reinforcement 21.01.52.6-1.2-0.9-1.3-1.3-1.1-1.4-1.5-1.1-0.9-0.9-0.2-1.4-1.6-1.4-1.5-1.5-1.4-0.8
Bone: marrow area2.65.615.0-3.7-3.9-2.6-2.7-2.8-2.2-1.9-2.3-1.7-1.73.1-1.5-0.4-0.5-0.4-1.52.23.4
Bone: maximum diameter2.03.88.5-2.9-2.4-2.5-2.4-2.6-2.2-2.1-2.3-1.5-1.51.6-1.7-1.6-1.5-1.5-1.60.01.0
Bone: maximum force1.22.06.0-2.2-1.3-2.4-1.5-1.4-1.9-2.0-1.7-1.5-1.50.8-0.8-0.9-0.9-1.0-1.30.0-0.0
Bone: maximum moment1.42.46.0-2.2-1.4-2.4-1.6-1.5-2.0-2.2-1.7-1.5-1.50.5-1.0-1.2-1.2-1.2-1.6-0.2-0.3
Mean time between licks in bursts1.43.58.30.91.70.71.80.91.31.81.41.01.01.82.92.62.52.72.62.40.9
Mean num. licks in bursts0.30.51.8-0.30.1-0.8-0.10.2-0.3-0.6-0.10.20.2-1.0-0.4-0.6-0.8-0.6-1.3-1.1-1.3
Cd content in liver4.65.110.52.72.32.62.52.62.82.62.73.23.2-1.41.71.71.71.71.6-0.4-0.8
Co content in liver0.50.53.10.7-0.81.5-0.10.00.60.70.20.10.10.4-0.40.20.30.30.91.11.8
Cu content in liver0.91.12.3-0.6-1.0-0.4-1.3-1.4-0.9-0.7-1.5-1.5-1.50.7-1.3-1.0-1.1-1.0-0.2-0.20.7
Fe content in liver0.60.72.71.61.21.20.91.00.90.80.70.60.6-0.70.20.20.10.30.3-1.0-0.9
K content in liver2.12.05.4-0.5-1.30.3-1.6-1.0-1.0-1.1-1.5-1.2-1.2-1.1-2.3-2.1-2.1-2.1-0.7-1.6-0.2
Mg content in liver2.42.48.41.10.11.8-0.60.30.2-0.2-0.40.20.2-2.9-2.1-2.2-2.3-2.2-0.6-2.8-1.3
Mn content in liver4.34.713.3-0.5-0.2-0.6-1.6-1.1-1.6-2.0-1.8-1.0-1.0-2.3-2.6-3.3-3.3-3.3-2.2-3.6-2.6
Na content in liver0.60.62.5-0.4-1.3-0.2-0.9-0.4-0.4-0.5-0.9-0.7-0.7-0.3-1.6-0.7-0.7-0.6-0.9-0.80.8
Rb content in liver1.21.44.80.5-0.51.2-0.70.2-0.2-0.5-0.4-0.1-0.1-2.2-1.8-1.8-1.8-1.8-0.9-1.9-0.8
Se content in liver1.31.53.92.01.91.71.31.11.61.71.10.90.9-0.40.90.70.70.72.0-0.5-0.6
Sr content in liver0.70.61.70.4-0.11.10.3-0.00.60.90.10.60.60.80.50.80.70.81.21.31.3
Zn content in liver0.10.20.50.60.20.7-0.00.20.10.10.20.10.1-0.6-0.4-0.4-0.4-0.40.5-0.6-0.4
Bone: minimum diameter4.88.821.1-4.6-3.9-3.8-3.5-3.9-3.4-3.1-3.4-2.8-2.83.4-1.9-1.4-1.4-1.4-1.71.82.3
Time in familiar zone, hab. session 11.51.52.21.01.41.01.41.51.41.31.31.31.3-0.31.41.41.21.41.20.5-0.0
Time in novel zone, hab. session 10.50.51.0-0.3-0.9-0.2-0.8-1.0-0.8-0.6-0.7-0.9-0.90.4-0.8-0.8-0.7-0.7-0.4-0.00.4
Total zone transitions, hab. session 11.52.13.61.31.61.61.61.51.51.61.31.51.5-0.11.91.51.51.61.81.20.1
Total locomotion distance, hab. session 10.10.10.6-0.8-0.5-0.4-0.4-0.2-0.5-0.6-0.5-0.1-0.10.30.0-0.1-0.2-0.0-0.20.60.1
Locomotion velocity, hab. session 10.20.31.0-1.0-0.7-0.7-0.5-0.3-0.7-0.7-0.6-0.1-0.10.50.0-0.0-0.1-0.0-0.30.70.1
Time in familiar zone, hab. session 21.01.02.40.81.40.21.21.10.80.90.80.30.30.31.61.41.41.41.40.9-0.3
Time in novel zone, hab. session 21.01.02.2-0.7-1.3-0.0-1.2-1.0-1.0-1.0-0.7-0.1-0.1-0.4-1.5-1.5-1.5-1.5-1.3-0.8-0.0
Total zone transitions, hab. session 21.51.94.31.71.32.11.51.61.71.61.11.51.5-0.81.21.21.21.21.50.70.2
Total locomotion distance, hab. session 20.71.01.91.21.01.41.11.31.21.10.91.01.0-0.60.90.90.80.91.00.5-0.0
Locomotion velocity, hab. session 20.91.22.01.21.11.41.21.41.31.21.01.31.3-0.71.11.01.01.01.10.5-0.1
Novel to familiar place preference ratio0.50.51.8-1.1-0.9-1.3-0.8-0.8-0.9-0.9-0.5-0.6-0.60.5-0.5-0.4-0.4-0.5-0.70.0-0.0
Novelty place preference0.50.51.3-1.0-0.9-1.2-0.8-0.8-0.9-1.0-0.6-0.5-0.50.4-0.6-0.6-0.5-0.7-0.7-0.1-0.0
Time in novel zone, NPP test0.40.51.2-0.9-0.7-1.1-0.8-0.8-0.9-0.9-0.6-0.5-0.50.3-0.6-0.6-0.6-0.7-0.7-0.2-0.2
Total zone transitions, NPP test1.42.15.01.61.51.91.51.81.51.41.32.22.2-1.81.10.60.60.70.8-0.3-0.9
Total locomotion distance, NPP test0.10.10.50.20.30.30.20.40.1-0.00.10.70.7-0.70.1-0.2-0.2-0.10.1-0.2-0.4
Locomotion velocity, NPP test0.10.20.70.20.30.50.40.60.40.30.40.80.8-0.60.40.20.20.30.30.1-0.0
Intraocular pressure0.20.31.70.00.0-0.20.2-0.20.20.60.10.20.21.30.50.70.70.60.70.81.0
Delta distance traveled before/after self-admin0.30.30.80.50.90.40.70.60.60.50.60.70.7-0.50.70.40.50.40.60.1-0.5
Delta ambulatory time before/after self-admin0.40.41.50.31.1-0.30.80.50.40.40.60.50.50.21.20.80.80.70.90.5-0.6
Parametrial fat weight0.30.81.8-0.9-0.3-1.3-0.8-0.5-1.3-1.4-0.8-0.5-0.5-0.1-0.6-1.0-1.0-1.0-1.2-0.8-1.1
Pavlov. Cond. lever latency2.73.37.02.32.02.51.91.92.32.12.02.72.7-1.41.21.11.11.21.3-0.6-0.6
Pavlov. Cond. magazine entry latency4.65.99.8-2.6-2.2-2.8-2.6-1.9-3.0-3.1-2.6-3.0-3.0-0.1-2.4-2.4-2.4-2.5-2.8-1.1-0.6
Pavlov. Cond. change in total contacts3.23.46.6-2.0-1.8-1.9-2.1-1.7-2.0-2.0-2.4-2.6-2.60.5-2.0-1.7-1.8-1.8-1.6-0.50.4
Pavlov. Cond. index score3.64.57.8-2.6-2.2-2.8-2.3-1.9-2.6-2.6-2.4-2.8-2.80.6-1.8-1.7-1.7-1.8-2.3-0.30.0
Pavlov. Cond. latency score3.34.28.2-2.5-2.1-2.7-2.2-1.9-2.6-2.5-2.3-2.9-2.90.8-1.7-1.6-1.6-1.7-2.0-0.10.1
Pavlov. Cond. lever contacts2.93.56.9-2.3-2.1-2.5-2.0-2.0-2.3-2.1-2.1-2.6-2.61.4-1.3-1.2-1.1-1.2-1.50.50.9
Pavlov. Cond. magazine entry number4.86.09.52.42.12.62.51.72.83.12.62.82.80.72.72.72.72.73.11.70.9
Pavlov. Cond. intertrial magazine entries0.40.41.3-0.00.1-0.10.4-0.00.60.80.40.40.41.10.61.00.90.90.70.70.9
Pavlov. Cond. lever-magazine prob. diff.4.25.28.4-2.7-2.4-2.8-2.5-2.1-2.8-2.8-2.6-2.9-2.90.6-2.1-2.0-2.0-2.1-2.4-0.40.1
Pavlov. Cond. response bias6.07.512.0-3.0-2.7-3.1-3.0-2.3-3.3-3.5-3.0-3.2-3.20.1-2.8-2.7-2.7-2.8-3.1-1.1-0.3
Pavlov. Cond. lever latency0.50.71.70.81.10.51.10.90.91.00.80.70.70.21.31.11.11.00.80.50.1
Pavlov. Cond. magazine entry latency0.60.71.31.00.61.10.91.01.11.01.10.90.9-0.50.60.70.80.80.80.30.2
Pavlov. Cond. change in total contacts0.81.33.9-0.9-2.0-0.1-1.5-1.2-0.9-0.9-1.2-1.2-1.20.2-1.9-1.2-1.1-1.1-0.7-0.21.2
Pavlov. Cond. index score0.20.31.1-0.4-1.00.1-0.8-0.5-0.3-0.4-0.4-0.3-0.3-0.1-1.0-0.6-0.5-0.6-0.20.00.5
Pavlov. Cond. latency score0.20.31.2-0.5-1.10.0-0.8-0.7-0.4-0.4-0.5-0.3-0.30.1-0.9-0.6-0.5-0.5-0.30.10.6
Pavlov. Cond. lever contacts0.50.81.6-0.7-1.0-0.4-1.1-0.8-0.9-1.0-0.8-0.6-0.6-0.4-1.3-1.2-1.2-1.1-0.8-0.7-0.3
Pavlov. Cond. magazine entry number0.40.51.4-0.9-0.4-1.2-0.6-1.0-0.9-0.6-0.8-0.9-0.91.0-0.1-0.2-0.3-0.3-0.40.20.3
Pavlov. Cond. intertrial magazine entries2.43.67.5-2.7-2.0-2.7-2.2-2.6-2.3-1.9-2.3-1.9-1.91.9-1.1-1.3-1.1-1.4-1.30.51.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.8-0.3-0.90.3-0.6-0.4-0.1-0.2-0.3-0.1-0.1-0.1-0.8-0.5-0.4-0.4-0.10.20.6
Pavlov. Cond. response bias0.30.41.0-0.3-0.6-0.0-0.6-0.2-0.4-0.6-0.3-0.1-0.1-0.8-1.0-0.9-0.9-0.8-0.7-0.8-0.4
Time in closed arm before self-admin0.60.73.80.91.20.50.50.60.30.00.20.20.2-1.3-0.0-0.7-0.6-0.7-0.2-1.7-2.0
Time in closed arm after self-admin5.05.413.42.93.71.42.83.02.21.82.72.62.6-2.32.21.21.21.21.1-1.4-3.0
Time in open arm before self-admin2.12.37.50.50.20.81.10.60.91.31.20.80.81.91.92.12.12.11.72.71.7
Time in open arm after self-admin2.02.29.1-1.6-2.0-0.6-1.2-1.7-0.7-0.2-1.1-1.1-1.12.8-0.20.60.50.70.62.43.0
Bone: periosteal estimation3.37.015.9-4.0-3.6-3.4-3.2-3.3-3.0-2.9-3.0-2.4-2.42.3-2.2-1.7-1.7-1.6-2.10.91.8
Bone: periosteal perimeter3.05.110.5-3.2-3.0-3.0-2.5-2.9-2.4-2.1-2.3-2.5-2.53.0-1.3-0.7-0.7-0.6-1.21.62.2
Bone: post-yield work1.42.18.2-1.6-1.3-1.5-0.5-1.1-0.7-0.3-0.4-0.9-0.92.90.81.21.11.10.52.82.5
Progressive ratio test 1 active lever presses0.70.93.3-1.4-1.6-0.7-1.1-1.2-0.6-0.5-1.0-0.5-0.51.2-0.80.00.0-0.0-0.30.91.8
Progressive ratio test 1 breakpoint0.91.13.3-1.6-1.7-1.0-1.2-1.4-0.8-0.6-1.1-0.6-0.61.3-0.8-0.00.0-0.1-0.40.91.8
Progressive ratio test 1 inactive lever presses2.13.06.1-2.4-1.8-2.3-2.0-2.5-1.9-1.7-2.2-2.0-2.01.9-1.4-1.0-1.0-1.1-0.80.11.1
Progressive ratio test 2 active lever presses0.91.02.9-1.4-1.7-0.9-1.2-1.2-0.7-0.6-1.0-0.8-0.81.3-0.8-0.0-0.10.0-0.21.11.7
Progressive ratio test 2 breakpoint0.91.03.1-1.4-1.7-0.9-1.2-1.2-0.7-0.6-0.9-0.8-0.81.3-0.8-0.0-0.10.1-0.31.11.7
Progressive ratio test 2 inactive lever presses0.91.43.7-1.7-1.2-1.8-1.3-1.7-1.1-0.8-1.4-1.2-1.21.9-0.6-0.1-0.1-0.00.10.71.4
Incentive Sensitization - Responses0.71.03.9-1.3-2.0-0.5-1.3-0.9-0.8-0.8-0.8-0.9-0.90.9-1.0-0.3-0.5-0.2-0.41.11.7
Incentive Sensitization - Breakpoint0.70.93.7-1.2-1.9-0.4-1.2-0.8-0.8-0.8-0.7-0.8-0.80.8-1.0-0.3-0.4-0.1-0.41.11.6
Sum of active levers in priming session hrs 5-60.40.31.50.5-0.91.1-0.10.30.80.70.30.20.2-0.3-0.80.10.10.1-0.10.11.2
Progressive ratio0.10.20.7-0.1-0.2-0.4-0.10.40.1-0.20.30.20.2-0.8-0.4-0.3-0.3-0.3-0.8-0.6-0.4
Food seeking constrained by brief footshock0.00.10.3-0.2-0.20.0-0.1-0.20.10.1-0.10.20.20.10.00.00.2-0.20.60.50.3
Seeking ratio, punishment vs. effort0.20.30.9-0.5-0.40.0-0.5-0.9-0.4-0.1-0.8-0.5-0.51.0-0.00.10.20.00.80.90.9
Retroperitoneal fat weight0.00.10.2-0.20.10.0-0.00.0-0.5-0.4-0.3-0.4-0.4-0.00.2-0.1-0.2-0.2-0.20.3-0.3
Reaction time number correct0.10.11.4-0.10.0-0.10.0-0.6-0.10.2-0.40.00.01.20.30.20.10.10.40.40.4
Reaction time mean minus median0.20.51.1-0.5-0.5-0.7-0.9-0.8-0.6-0.6-0.9-1.1-1.10.2-1.0-0.9-0.8-0.7-0.3-0.50.1
Reaction time mean minus median AUC0.40.92.7-0.1-0.3-0.3-0.8-0.6-0.4-0.6-0.7-0.8-0.8-0.8-1.5-1.4-1.5-1.3-0.9-1.6-0.8
Reaction time num false alarms0.50.63.4-1.0-0.6-1.4-0.6-1.3-0.7-0.4-0.9-0.2-0.21.90.10.20.20.0-0.10.80.8
Reaction time num false alarms AUC0.50.72.8-1.2-0.7-1.6-0.8-1.4-0.9-0.6-1.1-0.2-0.21.7-0.1-0.0-0.1-0.2-0.30.60.6
Reaction time trials correct on left0.10.11.4-0.10.0-0.10.0-0.6-0.10.2-0.40.00.01.20.30.20.10.10.40.40.4
Reaction time trials on left0.10.11.3-0.2-0.1-0.2-0.1-0.7-0.20.1-0.6-0.1-0.11.10.10.0-0.0-0.00.30.30.4
Reaction time mean1.22.05.1-0.5-1.0-0.5-1.4-0.9-0.9-1.1-1.2-2.3-2.3-1.0-2.1-1.9-1.6-1.8-0.9-1.5-0.2
Reaction time mean AUC1.11.74.5-0.2-0.9-0.2-1.2-0.6-0.5-0.8-0.9-2.1-2.1-1.1-2.0-1.8-1.5-1.7-0.8-1.6-0.2
Median of all reaction times1.52.25.6-0.6-1.2-0.4-1.5-0.9-0.9-1.2-1.2-2.4-2.4-1.0-2.2-2.0-1.7-2.0-0.9-1.4-0.0
Reaction time omissions4.66.812.0-2.1-2.7-2.0-3.0-2.3-2.5-2.7-2.6-2.8-2.8-0.6-3.5-3.2-3.2-3.1-3.0-1.8-0.3
Reaction time false alarm rate0.30.41.4-1.0-0.5-1.2-0.6-0.8-0.6-0.5-0.6-0.0-0.01.0-0.10.0-0.0-0.1-0.50.30.5
Reaction time premature initiation rate0.60.83.3-1.2-0.6-1.8-0.8-0.6-1.1-1.1-0.6-1.4-1.40.9-0.3-0.3-0.4-0.1-0.80.10.0
Reaction time premature initiations0.50.93.9-1.3-0.6-2.0-0.8-0.9-1.2-1.0-0.8-1.3-1.31.4-0.3-0.2-0.3-0.1-0.70.20.1
Std. dev. reaction times0.81.53.4-0.3-0.6-0.4-1.2-0.7-0.7-0.9-1.1-1.5-1.5-1.1-1.8-1.8-1.7-1.7-1.0-1.6-0.5
Reaction time trials completed0.10.11.3-0.2-0.1-0.2-0.1-0.7-0.20.1-0.6-0.1-0.11.10.10.0-0.0-0.00.30.30.4
Reaction time trials AUC0.10.11.1-0.1-0.1-0.1-0.1-0.6-0.10.1-0.5-0.1-0.11.00.10.0-0.0-0.00.30.20.4
Run reversals in cocaine runway, females0.90.91.90.50.70.10.80.60.60.90.70.70.70.71.41.31.11.41.21.31.0
Run reversals in cocaine runway, males0.60.61.5-1.1-0.7-1.1-0.9-1.0-1.2-1.1-0.9-0.8-0.80.1-0.4-0.7-0.5-0.7-0.60.1-0.3
Latency to leave start box in cocaine runway1.01.12.40.71.00.31.21.20.80.91.21.21.20.21.51.51.31.40.70.9-0.2
Latency to leave start box in cocaine runway, F3.33.88.31.11.30.61.91.51.51.91.91.91.91.42.72.82.72.91.82.30.8
Latency to leave start box in cocaine runway, M1.51.43.4-0.3-0.2-0.2-0.8-0.2-0.9-1.3-0.9-0.7-0.7-1.7-1.4-1.6-1.6-1.8-1.4-1.8-1.5
Std. dev. time between licks in bursts0.60.82.40.30.20.60.70.70.70.80.80.50.51.01.01.41.11.60.91.20.7
Total sessions with >9 infusions1.11.34.3-0.2-0.40.60.2-0.60.60.9-0.00.20.22.00.71.51.61.51.51.92.1
Short access day 1 total inactive lever presses0.81.12.4-1.2-1.5-0.7-1.3-1.6-1.2-1.0-1.4-0.9-0.91.4-0.8-0.5-0.4-0.6-0.30.91.2
Short access day 10 total inactive lever presses0.82.03.9-1.8-1.4-1.8-1.7-2.0-1.7-1.5-1.9-1.5-1.51.6-1.1-1.0-1.1-0.8-0.6-0.00.5
Short access day 1 total infusions0.40.52.1-0.8-0.9-0.4-0.9-1.5-0.5-0.3-1.2-0.2-0.21.2-0.9-0.2-0.1-0.3-0.1-0.20.9
Short access day 10 total infusions0.40.52.1-0.7-0.8-0.3-0.5-0.9-0.3-0.1-0.5-0.5-0.51.4-0.10.60.60.60.41.11.2
Short access total infusions0.50.62.4-0.9-0.9-0.4-0.7-1.3-0.4-0.1-1.0-0.5-0.51.5-0.40.30.30.30.30.71.4
Short access day 1 locomotion1.01.33.5-1.4-1.7-1.0-1.3-1.8-0.9-0.8-1.4-1.1-1.11.9-0.9-0.1-0.0-0.2-0.10.91.4
Short access day 10 total locomotion1.22.24.5-2.1-1.7-1.8-1.6-1.6-1.6-1.5-1.4-2.1-2.11.9-0.6-0.2-0.3-0.2-0.01.61.2
Short access total locomotion2.12.58.3-2.0-1.8-1.3-1.3-1.8-1.1-0.7-1.3-1.7-1.72.9-0.20.70.60.70.92.42.4
One hour access (0.3 mA shock)0.30.41.00.1-0.10.30.40.70.60.50.80.90.9-0.20.50.90.80.80.31.00.5
Compulsive drug intake0.10.20.70.60.20.80.20.60.1-0.00.4-0.1-0.1-0.8-0.0-0.3-0.3-0.20.2-0.1-0.6
One hour access (shock baseline)0.50.73.0-0.3-0.4-0.10.2-0.20.40.50.20.40.41.20.71.21.21.10.81.71.5
Social response proportion1.31.47.1-0.4-0.1-0.6-0.3-1.4-0.60.1-1.0-0.8-0.82.70.90.90.81.11.82.21.5
Social responses0.30.41.1-0.7-0.3-1.0-0.6-0.9-0.9-0.7-1.1-0.8-0.80.9-0.0-0.1-0.1-0.00.10.40.1
Social time2.02.77.2-1.6-1.4-1.3-1.5-2.5-1.5-0.8-1.8-2.4-2.42.7-0.4-0.2-0.1-0.11.11.72.1
Soleus weight0.20.72.8-0.0-0.00.10.2-0.60.20.6-0.0-0.2-0.21.60.90.80.80.81.41.71.2
Bone: stiffness0.10.10.4-0.30.2-0.60.30.50.1-0.10.20.50.5-0.10.40.40.40.4-0.10.20.0
Tibialis anterior weight0.41.35.30.10.00.30.4-0.20.61.00.2-0.1-0.11.91.21.51.41.51.92.31.4
Time to tail flick, vehicle, before self-admin0.90.92.91.20.81.50.81.30.90.61.01.21.2-1.70.2-0.1-0.1-0.2-0.2-0.9-1.0
Time to tail flick, vehicle, after self-admin0.50.61.2-0.8-0.6-1.1-0.8-0.8-0.9-1.0-0.9-0.9-0.9-0.2-0.8-0.7-0.7-0.7-0.9-0.6-0.4
Time to tail flick, test, before self-admin1.01.03.21.30.71.80.80.71.21.40.61.21.2-0.10.70.60.60.71.60.70.6
Time to tail flick, test, after self-admin0.10.10.2-0.10.0-0.0-0.2-0.4-0.00.1-0.40.40.40.3-0.1-0.2-0.3-0.20.2-0.20.4
Delta time to tail flick, vehicle, before/after SA1.91.83.6-1.8-1.6-1.9-1.6-1.8-1.6-1.5-1.7-1.6-1.60.8-1.2-0.9-0.9-0.8-0.90.10.7
Delta time to tail flick, test, before/after SA1.31.32.2-1.5-1.5-1.2-1.4-1.4-1.3-1.2-1.3-1.1-1.10.7-1.2-0.9-1.0-0.9-1.3-0.20.7
Tibia length0.51.36.70.72.2-0.81.30.80.10.10.50.40.4-0.12.01.01.01.00.30.2-2.6
Ambulatory time before self-admin0.40.71.8-0.8-1.3-0.4-1.0-0.7-0.5-0.7-0.7-0.9-0.90.3-1.3-0.7-0.8-0.7-1.1-0.40.6
Ambulatory time after self-admin0.10.10.4-0.5-0.3-0.6-0.3-0.2-0.3-0.4-0.1-0.5-0.50.2-0.3-0.2-0.1-0.2-0.3-0.1-0.1
Bone: tissue strength1.21.23.70.91.90.31.41.30.80.81.11.21.2-0.71.50.90.90.90.6-0.6-1.4
Total heroin consumption1.61.94.5-1.4-2.1-0.6-1.7-1.4-1.2-1.2-1.5-1.3-1.3-0.0-2.1-1.4-1.4-1.5-1.6-0.61.0
Bone: trabecular number3.96.411.0-2.7-2.3-3.2-2.8-2.6-3.3-3.3-2.6-2.8-2.80.4-2.4-2.6-2.5-2.5-2.8-1.1-0.4
Bone: trabecular spacing2.02.74.01.51.51.51.81.82.02.01.71.71.7-0.31.81.82.01.71.91.10.3
Bone: trabecular thickness1.51.83.5-1.6-1.3-1.8-1.4-1.9-1.7-1.5-1.6-1.8-1.81.6-0.8-0.7-0.7-0.6-0.90.30.7
Bone: trabecular tissue density0.40.63.20.61.00.40.50.80.2-0.00.30.60.6-1.40.2-0.3-0.3-0.3-0.5-1.2-1.8
Water consumed over 24 hours0.20.21.40.61.2-0.30.4-0.20.00.2-0.20.50.5-0.20.5-0.3-0.1-0.30.1-0.5-0.7
Number of responses in last shaping day1.01.14.2-1.7-0.9-1.7-0.9-1.5-1.1-0.7-1.1-0.7-0.72.10.10.40.40.30.01.01.2