Dcaf7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Dcaf7 0.1 0.05 9.6e-09 0.08 0.08 0.08 0.08 2.1e-09 7.5e-09 8.1e-09 7.7e-09
2 Adipose gene expression Dcaf7 0.11 0.05 1.3e-11 0.08 0.08 0.09 0.08 6.1e-09 7.9e-09 4.6e-10 5.9e-09
3 NAcc mRNA stability Dcaf7 0.07 0.04 1.2e-07 0.06 0.06 0.04 0.06 1.4e-07 4.3e-07 6.1e-05 3.5e-07
4 Liver gene expression Dcaf7 0.05 0.02 4.6e-06 0.04 0.05 0.05 0.05 3.6e-05 7.1e-06 2.1e-06 3.0e-06
5 Adipose mRNA stability Dcaf7 0.04 0.02 1.1e-05 0.03 0.04 0.04 0.03 7.7e-04 2.1e-05 4.3e-05 1.0e-04
6 PL gene expression Dcaf7 0.03 0.02 1.1e-04 0.03 0.04 0.03 0.03 2.6e-04 3.8e-05 1.1e-04 2.3e-04
7 Brain gene expression Dcaf7 0.04 0.03 4.7e-03 0.03 0.02 0.02 0.03 5.7e-04 3.1e-03 2.7e-03 1.3e-03
8 BLA gene expression Dcaf7 0.06 0.04 2.7e-03 0.02 0.03 0.05 0.03 3.2e-02 1.7e-02 1.7e-03 1.4e-02
9 Brain mRNA stability Dcaf7 0.11 0.05 1.8e-07 0.04 0.08 0.08 0.08 4.4e-05 5.5e-08 3.4e-08 4.7e-08
10 pVTA gene expression Dcaf7 0.12 0.06 1.4e-03 -0 0.03 0.05 0.02 3.7e-01 1.3e-02 4.8e-03 6.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.84.714.3-2.43.4-2.71.61.5-1.41.00.0-3.8-0.7
Area under the delay curve0.10.10.6-0.2-0.1-0.40.5-0.10.00.10.4-0.80.2
BMI with tail0.51.75.81.0-2.00.3-0.70.1-0.20.22.11.12.4
BMI without tail1.53.110.5-0.9-0.3-1.31.01.6-1.71.92.8-0.23.2
Body weight1.66.815.8-2.01.0-2.62.62.6-2.62.94.0-1.72.9
Weight adjusted by age0.80.92.11.0-1.51.0-0.8-1.01.0-0.60.01.30.3
Bone surface7.212.725.3-4.34.8-4.23.43.1-2.92.32.5-5.0-0.0
Bone volume6.110.420.9-3.84.4-4.03.12.8-2.62.21.9-4.60.1
Breakpoint value in progressive ratio session1.11.22.1-1.51.4-0.91.21.2-1.11.30.2-0.10.8
Number of licking bursts0.00.00.1-0.10.1-0.10.1-0.10.2-0.00.3-0.3-0.4
Context. condit. distance diff. score0.60.84.00.6-1.01.2-0.2-0.40.4-0.40.22.00.4
Locomotion velocity, session 11.61.86.0-1.51.7-1.41.11.1-1.10.70.6-2.4-0.2
Locomotion distance, session 10.30.32.6-0.20.3-0.50.40.0-0.1-0.1-0.2-1.6-0.5
Locomotion velocity, session 20.70.92.3-1.21.5-0.80.91.0-0.90.6-0.1-1.1-0.6
Locomotion distance, session 20.10.20.90.00.20.20.4-0.10.1-0.2-0.5-0.7-1.0
Locomotion velocity, session 30.20.20.70.2-0.10.1-0.5-0.50.6-0.7-0.5-0.4-0.8
Locomotion distance, session 30.10.20.5-0.40.5-0.40.20.00.1-0.20.1-0.7-0.7
Stereotopy head waving bouts, day 30.30.31.30.20.30.0-0.4-0.50.5-0.6-1.1-0.5-0.8
Stereotopy head waving duration, day 30.20.30.70.5-0.20.5-0.2-0.70.7-0.5-0.80.4-0.4
Locomotion velocity, session 70.30.30.70.4-0.30.5-0.7-0.50.5-0.8-0.9-0.1-0.7
Locomotion distance, session 70.10.10.40.2-0.60.50.1-0.20.1-0.3-0.40.60.4
Stereotopy head waving bouts, day 70.40.51.60.30.30.3-0.3-0.50.6-0.7-1.2-0.6-1.3
Stereotopy head waving duration, day 71.51.94.81.1-0.11.2-0.9-1.41.5-1.3-2.10.2-2.2
Locomotion velocity, session 80.40.52.2-0.30.0-0.20.80.7-0.60.91.50.20.4
Locomotion distance, session 80.20.21.40.3-0.30.70.5-0.10.10.1-0.31.20.0
Degree of sensitization distance0.30.31.10.2-0.80.50.50.1-0.30.30.20.81.1
Degree of sensitization stereotypy0.91.02.80.8-0.30.9-0.8-0.91.0-1.1-1.3-0.1-1.7
Conditioned locomotion0.40.51.5-0.30.3-0.50.90.8-0.91.00.00.21.2
Cocaine response after cond. corrected0.30.40.90.3-0.70.2-0.5-0.70.8-0.90.70.0-0.6
Cocaine response after cond. not corrected0.60.72.5-0.10.10.1-0.6-0.70.9-1.30.4-0.9-1.6
Cocaine response before conditioning0.60.72.3-0.51.2-0.1-0.1-0.10.2-0.5-0.8-1.5-1.5
Saline control response1.41.85.1-0.80.6-0.71.21.6-1.71.71.00.92.3
Bone: connectivity density3.35.213.1-2.73.5-2.72.01.8-1.71.10.2-3.6-0.6
Bone: cortical apparent density3.95.111.52.6-1.92.0-2.3-2.62.4-2.0-3.41.5-1.3
Bone: cortical area2.53.78.1-2.32.2-2.71.51.6-1.51.31.7-2.80.5
Bone: cortical porosity11.312.320.6-4.53.9-3.92.33.7-3.42.44.2-4.11.0
Bone: cortical porosity7.17.713.3-3.52.9-3.21.82.8-2.51.83.6-3.60.6
Bone: cortical thickness2.13.46.71.5-1.00.5-2.6-2.22.2-2.3-2.1-1.1-1.8
Bone: cortical thickness2.32.75.51.0-0.50.9-2.3-1.71.7-2.3-2.2-0.6-1.9
Bone: cortical tissue density3.85.011.42.6-1.82.0-2.2-2.52.3-1.9-3.41.5-1.2
Condit. Reinf. active minus inactive responses2.73.04.7-2.22.0-1.61.92.1-2.01.61.4-1.11.2
Condit. Reinf. active-inactive response ratio1.11.22.4-1.51.6-0.71.41.3-1.30.70.8-0.50.6
Condit. Reinf. active responses3.34.05.6-2.32.2-2.02.42.3-2.32.21.3-1.11.5
Condit. Reinf. inactive responses1.11.32.6-1.01.0-1.51.41.0-1.11.60.5-1.00.7
Incentive salience index mean3.03.66.6-2.32.6-2.01.92.1-2.01.61.1-1.90.5
Condit. Reinf. lever presses0.71.02.3-1.01.5-1.20.70.9-0.91.0-0.1-1.2-0.3
Condit. Reinf. active minus inactive responses5.97.313.9-3.63.7-2.93.12.7-2.52.21.9-2.50.3
Condit. Reinf. active-inactive response ratio4.64.89.9-3.03.1-2.52.12.2-2.01.61.4-2.30.0
Condit. Reinf. active responses5.88.012.4-3.53.5-3.03.33.0-3.02.72.0-2.11.4
Condit. Reinf. inactive responses1.41.83.1-1.11.0-1.21.71.5-1.61.70.60.11.8
Condit. Reinf. lever presses1.62.23.7-1.91.9-1.61.31.8-1.71.31.1-1.10.7
Condit. Reinf. lever reinforcers received5.17.111.4-3.43.3-2.93.02.8-2.82.51.9-2.11.3
Conditioned reinforcement - actives0.60.60.9-0.60.7-0.50.60.9-0.90.91.0-0.10.9
Conditioned reinforcement - inactives1.01.11.5-1.11.0-1.21.21.2-1.21.01.2-0.80.6
Conditioned locomotion2.42.93.9-1.92.0-1.81.51.9-1.91.71.4-1.41.3
Patch foraging indifference point 0 sec3.35.210.4-2.42.2-2.43.22.5-2.62.61.3-0.91.9
Patch foraging indifference point AUC0.80.92.2-0.50.7-0.81.50.9-1.01.20.9-0.31.1
Delay disc. indifference point, 0s delay0.50.61.50.8-0.60.6-0.4-1.01.0-0.8-1.20.0-0.5
Delay disc. indifference point, 16s delay0.50.51.1-0.50.0-0.90.70.4-0.40.60.9-0.81.1
Delay disc. indifference point, 2s delay0.50.51.4-0.61.0-0.91.20.0-0.10.5-0.3-1.1-0.6
Delay disc. indifference point, 24s delay1.61.62.7-0.80.6-1.31.51.1-1.21.41.4-1.11.6
Delay disc. indifference point, 4s delay0.60.61.10.4-0.50.3-1.0-0.91.0-1.0-0.3-0.7-1.0
Delay disc. indifference point, 8s delay0.20.20.50.2-0.30.00.0-0.60.5-0.4-0.6-0.7-0.3
Indifference point function ln k0.20.20.8-0.30.4-0.4-0.5-0.30.4-0.3-0.9-0.4-0.6
Indifference point function log k0.20.20.8-0.30.4-0.4-0.5-0.30.4-0.3-0.9-0.4-0.6
Patch foraging total patch changes 0 sec3.65.710.6-2.52.3-2.53.32.6-2.72.61.6-1.22.0
Patch foraging total patch changes 12 sec3.54.512.6-1.82.0-1.73.52.3-2.42.51.2-0.31.8
Patch foraging total patch changes 18 sec2.33.04.5-1.71.2-1.52.12.0-2.01.82.0-0.41.8
Patch foraging total patch changes 24 sec3.34.07.1-2.12.3-2.12.72.0-2.02.01.4-1.61.2
Patch foraging total patch changes 6 sec2.13.16.1-1.91.9-1.82.51.8-1.91.71.5-1.01.3
Patch foraging time to switch 0 sec0.10.10.60.1-0.30.5-0.8-0.20.2-0.4-0.10.3-0.4
Patch foraging water rate 0 sec1.22.03.0-1.31.2-1.71.61.5-1.61.41.0-1.31.3
Patch foraging water rate 12 sec0.81.12.70.7-0.80.6-1.3-1.31.3-1.6-0.3-0.8-1.2
Patch foraging water rate 18 sec0.50.72.2-0.41.0-0.40.2-0.30.4-0.7-0.8-1.4-1.5
Patch foraging water rate 24 sec0.10.10.40.1-0.10.00.1-0.30.4-0.5-0.3-0.5-0.7
Patch foraging water rate 6 sec0.30.52.5-0.50.7-0.7-0.2-0.10.1-0.3-0.5-1.6-0.5
Seeking ratio, delayed vs. immediate footshock0.10.10.50.4-0.20.3-0.10.3-0.3-0.10.10.60.7
Distance traveled before self-admin0.50.52.6-0.0-0.60.1-0.4-0.60.8-0.61.6-0.5-0.7
Distance traveled after self-admin0.30.31.80.0-0.30.5-0.1-0.20.4-0.61.4-0.0-0.5
Extensor digitorum longus weight2.28.724.13.8-4.92.7-2.8-1.91.6-0.5-0.24.52.6
Bone: elastic displacement1.21.33.10.8-0.60.7-1.4-1.21.3-1.6-0.7-0.7-1.8
Bone: elastic work0.60.74.0-0.70.8-1.0-0.40.3-0.2-0.10.5-2.0-0.7
Bone: endosteal estimation13.128.639.8-6.35.7-5.45.86.0-5.85.15.6-3.73.1
Bone: endosteal perimeter14.830.744.0-6.35.4-5.66.35.9-5.75.36.6-3.93.4
Epididymis fat weight0.81.95.6-0.90.1-1.51.01.4-1.61.41.7-0.12.4
Delta time in closed arm before/after self-admin0.40.41.6-0.30.50.10.3-0.00.2-0.50.2-1.1-1.3
Delta time in open arm before/after self-admin1.01.04.21.2-0.90.5-0.6-0.50.30.2-1.12.01.1
Diff in mean of infusions in LGA sessions0.60.71.20.9-1.11.0-1.0-0.90.8-0.7-0.41.0-0.1
Delay discount exponential model param0.20.30.80.4-0.20.6-0.7-0.20.2-0.4-0.60.9-0.3
Extinction: sum of active levers before priming0.60.61.6-0.40.2-0.20.90.5-0.50.9-0.21.31.2
Active lever presses in extinction session 62.62.63.6-1.91.6-1.71.51.9-1.81.71.4-0.71.5
Bone: final force1.32.28.0-1.71.9-1.81.10.8-0.70.31.0-2.8-0.5
Bone: final moment1.52.59.2-1.82.1-1.91.10.9-0.80.41.0-3.0-0.6
Food consumed during 24 hour testing period2.63.26.1-1.20.6-1.61.72.0-2.02.32.5-0.12.2
Glucose0.81.22.51.1-1.61.1-1.4-1.21.3-1.0-0.11.0-0.4
Heart weight0.20.31.10.3-1.00.0-0.0-0.30.3-0.00.90.50.6
Delay discount hyperbolic model param0.10.20.60.2-0.10.5-0.60.00.0-0.2-0.30.8-0.1
Intermittent access intake day 1-15 change0.40.41.4-0.40.1-0.30.10.7-0.70.41.20.80.6
Intermittent access intake escalation0.10.10.7-0.1-0.00.1-0.30.4-0.30.00.50.80.2
Intermittent access intake escalation 20.50.50.9-0.70.6-0.60.31.0-0.90.70.90.20.5
Intermitt. access day 1 inactive lever presses4.95.28.1-2.72.8-2.72.72.4-2.42.01.5-2.10.7
Intermitt. access day 15 inactive lever presses3.33.65.7-2.22.0-2.41.02.3-2.31.61.0-1.71.8
Intermitt. access escalation Index3.32.94.81.8-1.62.0-1.2-2.12.2-1.8-0.81.3-1.8
Intermittent access day 1 total infusions0.70.81.3-0.90.7-1.21.00.8-0.81.11.1-0.70.8
Intermittent access day 15 total infusions0.50.61.7-0.50.2-0.60.40.8-0.80.91.30.41.1
Intermittent access terminal intake (last 3 days)2.12.33.3-1.51.3-1.61.21.7-1.81.81.8-0.31.6
Intermittent access total infusions2.42.63.7-1.61.5-1.81.61.8-1.81.91.8-0.61.4
Intermittent access day 1 locomotion4.04.15.3-2.21.8-2.12.12.1-2.12.12.3-2.11.4
Intermittent access day 15 total locomotion4.44.76.2-2.22.2-2.12.42.5-2.52.42.2-1.71.3
Intermittent access total locomotion7.28.310.3-3.02.9-3.02.93.2-3.23.02.7-2.41.9
Intermittent access standard deviation1.51.62.7-1.41.1-1.50.71.6-1.61.31.3-0.71.1
Left kidney weight0.41.22.11.0-1.00.8-1.1-1.41.4-1.5-0.7-0.2-1.2
Right kidney weight0.30.82.50.4-0.10.2-0.5-0.90.9-1.0-0.5-1.4-1.6
Cocaine induced anxiety0.30.42.8-0.3-0.1-0.4-0.6-0.20.2-0.50.3-1.7-0.2
Post-drug Anxiety0.40.52.5-0.1-0.5-0.2-0.8-0.40.4-0.70.4-1.6-0.1
Baseline Anxiety0.70.71.11.0-0.90.8-0.9-1.01.0-1.0-0.70.3-0.6
Tail length2.16.38.2-2.82.4-2.82.72.6-2.62.92.2-2.31.7
Length with tail1.97.19.9-2.92.8-3.13.12.5-2.42.82.4-3.00.6
Length without tail0.51.12.5-0.91.4-1.21.20.6-0.50.70.4-1.6-1.0
Times rat made contact with spout0.60.71.6-0.80.8-0.80.61.0-1.00.91.3-0.70.4
Lifetime Intake3.03.44.5-1.91.9-2.11.82.0-2.12.11.6-0.71.6
Liver weight, left0.71.12.9-1.11.7-1.11.50.8-0.71.10.4-0.9-0.3
Liver weight, right0.71.12.40.7-0.10.1-0.5-1.21.2-1.3-1.2-1.4-1.5
Locomotor activity0.30.51.4-0.70.8-0.41.20.9-0.90.80.6-0.10.2
Locomotor testing distance1.32.23.7-1.51.2-1.01.51.9-1.91.51.7-0.21.5
Locomotor testing rearing1.11.73.7-1.30.8-0.41.11.9-1.91.21.60.31.4
Locomotion in novel chamber0.40.52.0-0.00.30.5-0.2-0.40.6-0.80.7-0.7-1.4
Locomotion in novel chamber post-restriction1.72.03.5-1.61.5-1.61.91.1-1.01.81.3-1.40.4
Fecal boli incidents, locomotor time 10.10.10.50.1-0.50.10.3-0.00.10.20.60.10.7
Change in fecal boli incidents, locomotor task0.40.41.00.7-1.00.2-0.7-0.50.4-0.50.00.90.5
Time >=10cm from walls, locomotor time 12.82.84.11.5-1.41.9-1.7-1.92.0-1.9-0.91.3-1.9
Bouts of movement, locomotor time 10.20.30.90.6-0.50.4-0.7-0.40.3-0.4-0.90.10.2
Total resting periods, locomotor time 10.30.31.10.6-0.50.4-0.8-0.50.4-0.5-1.0-0.20.0
Rest time, locomotor task time 10.20.21.30.10.10.1-0.5-0.30.3-0.3-1.1-0.5-0.3
Distance moved, locomotor task time 10.30.41.3-0.50.3-0.70.50.8-0.70.51.2-0.20.3
Vertical activity count, locomotor time 10.30.30.7-0.60.7-0.80.30.6-0.50.20.8-0.2-0.2
Time >=10cm from walls, locomotor time 20.30.31.1-0.30.20.1-0.9-0.10.2-0.70.3-0.3-1.1
Bouts of movement, locomotor time 20.30.31.00.5-0.90.2-0.7-0.20.2-0.1-0.30.81.0
Total resting periods, locomotor time 20.50.51.50.7-1.20.5-0.9-0.60.5-0.5-0.40.90.7
Rest time, locomotor task time 23.13.55.42.1-2.12.0-1.6-2.32.3-1.9-1.91.4-0.7
Distance moved, locomotor task time 20.60.71.7-1.01.3-0.90.11.2-1.10.50.5-0.8-0.4
Vertical activity count, locomotor time 23.33.66.6-2.32.6-2.21.22.4-2.41.81.0-1.20.8
Light reinforcement 10.40.72.0-0.40.5-1.01.00.5-0.71.2-0.50.11.4
Light reinforcement 20.70.91.9-0.71.2-1.41.00.8-0.91.0-0.8-0.70.9
Bone: marrow area12.827.839.2-6.35.6-5.35.75.9-5.75.05.6-3.73.0
Bone: maximum diameter5.610.415.4-3.93.7-3.93.43.0-2.92.73.3-3.31.2
Bone: maximum force1.93.38.0-2.01.9-2.41.81.4-1.31.21.8-2.80.5
Bone: maximum moment2.23.79.3-2.12.1-2.61.71.5-1.41.21.8-3.10.4
Mean time between licks in bursts0.20.31.70.2-0.7-0.10.30.0-0.00.31.30.10.8
Mean num. licks in bursts0.30.31.0-0.30.2-0.40.20.7-0.80.60.50.11.0
Cd content in liver4.14.58.92.4-2.43.0-1.8-2.12.1-2.2-1.71.8-1.1
Co content in liver0.60.72.41.0-1.01.4-0.4-0.50.5-0.4-0.21.6-0.1
Cu content in liver0.40.50.9-0.70.8-0.90.50.8-0.90.8-0.2-0.20.9
Fe content in liver0.40.41.70.3-0.20.7-0.5-0.50.5-0.5-1.30.9-0.5
K content in liver1.11.13.0-0.91.5-1.31.70.7-0.61.30.0-0.7-0.3
Mg content in liver0.50.52.20.10.8-0.40.90.0-0.10.9-1.50.3-0.2
Mn content in liver0.80.92.8-0.21.3-0.60.9-0.30.30.1-1.7-1.0-1.6
Na content in liver0.60.61.8-0.81.4-0.71.30.5-0.41.0-0.30.3-0.1
Rb content in liver3.03.77.92.1-1.22.0-1.2-2.22.2-1.7-2.81.4-2.0
Se content in liver1.51.82.71.5-1.31.7-0.5-1.61.5-1.0-1.31.7-0.8
Sr content in liver0.60.61.6-0.90.7-0.90.50.6-0.50.21.2-1.3-0.0
Zn content in liver0.30.31.2-0.40.9-0.31.1-0.20.20.10.0-0.8-0.7
Bone: minimum diameter12.924.030.4-5.54.8-5.45.15.1-5.04.85.5-4.13.2
Time in familiar zone, hab. session 10.80.72.0-0.2-0.4-0.20.90.7-0.71.11.01.01.4
Time in novel zone, hab. session 10.90.92.10.4-0.10.5-1.5-0.90.9-1.5-1.1-0.7-1.1
Total zone transitions, hab. session 10.20.20.90.0-0.3-0.30.40.3-0.30.40.8-1.00.1
Total locomotion distance, hab. session 11.01.56.2-1.21.2-1.51.01.0-1.00.60.6-2.5-0.4
Locomotion velocity, hab. session 11.31.85.9-1.31.3-1.61.41.2-1.20.90.8-2.4-0.2
Time in familiar zone, hab. session 21.01.02.0-0.70.4-0.01.41.1-1.11.21.40.61.2
Time in novel zone, hab. session 21.21.22.30.6-0.3-0.1-1.4-1.11.1-1.4-1.5-1.0-1.3
Total zone transitions, hab. session 20.10.10.20.4-0.30.10.50.1-0.10.50.1-0.4-0.0
Total locomotion distance, hab. session 20.30.41.1-0.10.4-0.71.10.5-0.70.9-0.3-0.80.3
Locomotion velocity, hab. session 20.30.41.2-0.10.3-0.61.10.4-0.50.8-0.2-0.90.2
Novel to familiar place preference ratio0.40.40.9-0.80.6-0.80.40.6-0.50.50.9-0.40.5
Novelty place preference0.20.20.4-0.60.5-0.50.10.3-0.30.20.6-0.20.3
Time in novel zone, NPP test0.10.10.3-0.60.5-0.40.00.2-0.2-0.00.5-0.30.0
Total zone transitions, NPP test0.20.21.30.3-0.1-0.20.6-0.20.10.2-0.4-1.1-0.6
Total locomotion distance, NPP test0.70.93.8-0.70.9-1.11.10.7-0.70.6-0.2-1.9-0.5
Locomotion velocity, NPP test0.30.51.6-0.30.3-0.91.00.5-0.60.7-0.0-1.30.1
Intraocular pressure1.11.57.1-0.5-0.6-1.00.51.0-1.21.31.5-0.02.7
Delta distance traveled before/after self-admin0.30.31.00.6-0.10.9-0.4-0.30.3-0.6-1.00.4-0.4
Delta ambulatory time before/after self-admin0.10.10.90.20.40.30.30.1-0.1-0.1-1.0-0.1-0.2
Parametrial fat weight1.32.66.5-1.72.1-2.31.31.3-1.31.30.5-2.60.1
Pavlov. Cond. lever latency2.93.76.62.1-2.62.4-1.6-1.91.8-1.6-1.22.50.2
Pavlov. Cond. magazine entry latency4.35.68.9-2.63.0-2.92.42.5-2.42.31.3-2.70.6
Pavlov. Cond. change in total contacts4.04.37.6-2.22.8-2.61.82.3-2.22.11.1-2.10.6
Pavlov. Cond. index score3.84.98.5-2.42.9-2.82.12.3-2.22.21.3-2.40.4
Pavlov. Cond. latency score3.13.96.7-2.12.6-2.52.02.1-1.92.01.3-2.10.3
Pavlov. Cond. lever contacts2.52.94.6-1.82.2-2.11.31.8-1.71.71.3-2.10.2
Pavlov. Cond. magazine entry number3.54.49.12.3-3.02.6-2.1-2.12.1-2.0-0.62.4-0.3
Pavlov. Cond. intertrial magazine entries1.01.33.8-0.4-0.4-0.61.40.8-1.01.61.01.12.0
Pavlov. Cond. lever-magazine prob. diff.3.74.67.7-2.32.8-2.81.92.2-2.12.11.4-2.40.4
Pavlov. Cond. response bias5.16.212.1-2.83.5-3.22.12.4-2.32.11.0-3.30.1
Pavlov. Cond. lever latency0.30.41.00.9-1.00.5-0.9-0.60.5-0.5-0.40.30.0
Pavlov. Cond. magazine entry latency2.42.74.11.7-1.52.0-1.6-1.92.0-1.7-1.01.3-1.6
Pavlov. Cond. change in total contacts0.20.31.1-0.50.70.01.10.5-0.50.70.30.40.1
Pavlov. Cond. index score0.10.10.4-0.10.20.40.0-0.20.3-0.30.20.1-0.6
Pavlov. Cond. latency score0.10.10.7-0.10.20.4-0.1-0.30.4-0.50.2-0.0-0.8
Pavlov. Cond. lever contacts0.20.20.6-0.70.8-0.40.70.5-0.50.40.2-0.20.0
Pavlov. Cond. magazine entry number3.03.75.3-1.81.6-2.31.82.2-2.32.21.3-1.22.1
Pavlov. Cond. intertrial magazine entries13.016.921.9-4.13.3-4.74.14.6-4.74.73.7-2.94.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.00.10.5-0.1-0.40.5-0.40.10.1-0.7
Pavlov. Cond. response bias0.00.00.2-0.20.30.20.2-0.10.2-0.2-0.10.1-0.5
Time in closed arm before self-admin0.91.02.20.8-0.31.0-1.3-0.80.9-1.3-1.10.0-1.5
Time in closed arm after self-admin1.41.45.60.8-0.21.5-0.7-1.01.2-1.5-0.7-0.1-2.4
Time in open arm before self-admin0.40.50.80.3-0.90.6-0.7-0.70.8-0.90.7-0.4-0.6
Time in open arm after self-admin0.60.73.70.1-0.7-0.50.00.3-0.40.70.90.91.9
Bone: periosteal estimation10.221.030.4-5.55.2-5.34.74.8-4.64.04.5-4.32.2
Bone: periosteal perimeter6.110.115.4-3.93.6-3.73.23.0-2.72.33.9-3.40.9
Bone: post-yield work2.23.07.6-1.91.4-1.71.81.8-1.61.52.8-1.11.0
Progressive ratio test 1 active lever presses4.14.37.1-2.22.3-2.32.72.2-2.22.21.8-1.11.3
Progressive ratio test 1 breakpoint5.55.79.0-2.52.5-2.63.02.6-2.62.62.0-1.01.9
Progressive ratio test 1 inactive lever presses4.24.67.3-2.32.4-2.32.72.3-2.32.51.7-0.71.6
Progressive ratio test 2 active lever presses4.85.26.8-2.52.4-2.52.62.4-2.52.42.0-1.41.7
Progressive ratio test 2 breakpoint5.96.78.5-2.82.7-2.82.92.8-2.82.72.5-1.61.9
Progressive ratio test 2 inactive lever presses4.14.76.6-2.12.0-2.52.32.3-2.42.62.0-1.32.0
Incentive Sensitization - Responses3.13.24.6-1.91.8-1.92.11.9-1.91.91.9-0.91.3
Incentive Sensitization - Breakpoint2.92.94.2-1.91.7-1.72.11.8-1.81.81.9-1.01.1
Sum of active levers in priming session hrs 5-60.70.73.40.3-0.30.7-0.1-0.40.30.2-1.41.80.6
Progressive ratio0.20.20.60.3-0.70.30.3-0.50.5-0.40.3-0.1-0.4
Food seeking constrained by brief footshock2.63.14.8-1.71.5-1.42.22.1-2.12.02.1-0.81.4
Seeking ratio, punishment vs. effort1.21.52.7-1.21.4-1.10.91.6-1.61.41.0-0.61.1
Retroperitoneal fat weight1.13.55.4-1.61.6-2.02.32.2-2.32.01.5-1.71.3
Reaction time number correct0.70.91.81.0-1.10.7-1.0-1.31.3-1.1-0.30.2-0.9
Reaction time mean minus median0.20.30.80.7-0.60.4-0.9-0.40.4-0.5-0.90.1-0.1
Reaction time mean minus median AUC1.11.42.41.4-1.01.0-1.3-1.41.3-1.2-1.60.2-1.0
Reaction time num false alarms3.04.16.0-2.42.1-2.22.32.1-2.02.22.0-1.61.1
Reaction time num false alarms AUC3.54.86.8-2.62.5-2.52.52.2-2.12.41.6-1.91.1
Reaction time trials correct on left0.70.91.81.0-1.10.7-1.0-1.31.3-1.1-0.30.2-0.9
Reaction time trials on left0.60.91.70.9-1.10.6-1.0-1.31.3-1.1-0.30.1-0.9
Reaction time mean0.81.13.60.9-0.30.8-1.1-1.01.0-1.1-1.90.1-1.3
Reaction time mean AUC1.01.44.51.0-0.51.0-1.3-1.11.1-1.2-2.10.3-1.3
Median of all reaction times0.81.13.50.8-0.30.8-1.0-1.01.0-1.2-1.90.1-1.4
Reaction time omissions0.20.31.4-0.30.4-0.6-0.40.1-0.1-0.2-0.8-1.2-0.1
Reaction time false alarm rate3.75.17.3-2.72.6-2.32.52.5-2.42.51.6-1.61.3
Reaction time premature initiation rate1.01.42.6-1.11.0-1.01.01.2-1.31.01.3-1.01.6
Reaction time premature initiations0.30.51.1-0.50.4-0.60.50.5-0.50.51.1-0.81.0
Std. dev. reaction times0.40.52.40.7-0.20.4-0.9-0.60.6-0.7-1.6-0.1-0.7
Reaction time trials completed0.60.91.70.9-1.10.6-1.0-1.31.3-1.1-0.30.1-0.9
Reaction time trials AUC0.71.01.81.0-1.20.7-1.0-1.41.4-1.1-0.40.2-0.9
Run reversals in cocaine runway, females0.40.42.00.4-0.9-0.2-1.4-0.1-0.0-0.60.2-0.70.5
Run reversals in cocaine runway, males0.10.10.70.1-0.30.0-0.2-0.30.3-0.50.3-0.8-0.3
Latency to leave start box in cocaine runway0.30.31.10.5-0.30.6-1.1-0.60.6-0.7-0.30.1-0.5
Latency to leave start box in cocaine runway, F0.60.71.50.5-0.70.7-1.2-0.91.0-1.20.2-0.3-0.9
Latency to leave start box in cocaine runway, M0.20.21.20.30.50.4-0.40.0-0.10.3-1.10.40.0
Std. dev. time between licks in bursts0.10.10.50.3-0.50.0-0.20.1-0.10.2-0.00.10.7
Total sessions with >9 infusions0.10.10.3-0.10.2-0.50.60.2-0.30.50.10.30.4
Short access day 1 total inactive lever presses1.01.11.8-1.21.2-1.21.01.0-1.00.71.2-1.30.1
Short access day 10 total inactive lever presses0.80.92.0-0.70.3-1.21.01.0-1.11.10.6-0.11.4
Short access day 1 total infusions0.91.01.8-0.91.0-1.11.31.0-1.01.30.50.41.1
Short access day 10 total infusions5.86.58.6-2.62.3-2.92.42.9-2.92.92.3-1.22.5
Short access total infusions3.33.74.9-2.12.1-2.21.92.2-2.22.21.5-0.51.7
Short access day 1 locomotion3.43.65.3-1.81.5-2.21.92.0-2.12.21.8-0.82.3
Short access day 10 total locomotion10.211.415.1-3.43.0-3.53.63.9-3.93.73.2-2.52.8
Short access total locomotion5.15.37.3-2.32.0-2.42.32.7-2.72.62.4-1.22.2
One hour access (0.3 mA shock)1.01.11.8-1.21.0-1.01.11.2-1.21.21.40.10.9
Compulsive drug intake1.11.12.30.7-0.81.0-0.9-1.31.4-1.4-0.2-0.5-1.5
One hour access (shock baseline)1.31.52.4-1.01.2-1.21.11.5-1.51.50.80.61.3
Social response proportion0.30.30.90.8-1.00.4-0.5-0.50.5-0.40.10.40.3
Social responses0.10.10.2-0.20.2-0.10.40.2-0.20.40.00.00.5
Social time0.20.31.3-0.4-0.1-0.30.10.5-0.40.11.10.30.7
Soleus weight0.20.52.5-0.80.5-0.80.30.6-0.50.61.6-0.20.5
Bone: stiffness0.60.92.6-0.90.9-1.01.60.6-0.50.90.9-1.20.1
Tibialis anterior weight0.51.87.70.5-1.2-0.20.00.8-1.01.61.51.62.8
Time to tail flick, vehicle, before self-admin0.40.41.1-0.10.2-0.1-0.5-0.60.7-0.8-0.2-1.0-1.1
Time to tail flick, vehicle, after self-admin0.60.71.7-0.60.6-1.01.30.6-0.61.00.6-0.51.0
Time to tail flick, test, before self-admin0.60.61.30.8-0.91.1-1.1-0.60.7-1.0-0.00.5-0.4
Time to tail flick, test, after self-admin0.10.10.50.1-0.2-0.1-0.4-0.30.3-0.3-0.0-0.7-0.2
Delta time to tail flick, vehicle, before/after SA2.22.13.6-1.21.4-1.51.91.6-1.71.90.5-0.21.7
Delta time to tail flick, test, before/after SA0.10.10.3-0.10.2-0.40.4-0.10.10.3-0.5-0.3-0.2
Tibia length0.30.84.5-0.20.3-0.40.2-0.50.6-0.80.4-2.1-1.5
Ambulatory time before self-admin0.40.42.9-0.2-0.30.0-0.1-0.30.5-0.41.7-0.3-0.6
Ambulatory time after self-admin0.30.31.8-0.40.2-0.10.40.2-0.1-0.21.3-0.7-0.3
Bone: tissue strength1.31.32.11.3-1.11.0-0.8-1.41.5-1.2-0.8-0.1-1.3
Total heroin consumption0.60.72.3-1.21.5-0.90.90.7-0.60.60.2-0.9-0.4
Bone: trabecular number3.55.414.2-2.83.5-2.82.21.7-1.71.20.4-3.8-0.5
Bone: trabecular spacing1.52.07.41.7-2.01.8-0.8-0.80.8-0.30.12.70.5
Bone: trabecular thickness4.65.614.4-2.83.0-3.31.62.0-1.91.41.2-3.80.4
Bone: trabecular tissue density1.11.52.71.2-0.90.7-1.0-1.61.6-1.5-1.4-0.6-1.2
Water consumed over 24 hours0.10.10.4-0.10.1-0.4-0.10.2-0.20.20.4-0.6-0.0
Number of responses in last shaping day1.21.32.8-1.41.0-1.40.81.2-1.10.81.7-0.50.8