Dcaf7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Dcaf7 0.14 0.07 2.0e-06 0.09 0.12 0.14 0.13 1.6e-04 6.5e-06 2.2e-06 4.0e-06
2 PL mRNA stability Dcaf7 0.11 0.05 1.3e-08 0.09 0.07 0.07 0.08 1.0e-09 1.3e-08 1.5e-08 2.0e-09
3 Adipose gene expression Dcaf7 0.11 0.05 7.5e-12 0.09 0.08 0.08 0.08 5.9e-10 2.8e-09 2.4e-09 2.5e-09
4 Adipose mRNA stability Dcaf7 0.04 0.02 9.2e-06 0.03 0.04 0.04 0.04 4.3e-04 2.0e-05 8.6e-05 7.1e-05
5 PL gene expression Dcaf7 0.03 0.02 8.9e-05 0.04 0.04 0.04 0.04 3.7e-05 2.3e-05 4.5e-05 2.4e-05
6 Liver gene expression Dcaf7 0.04 0.02 6.3e-06 0.03 0.05 0.05 0.05 3.5e-04 5.6e-06 2.3e-06 4.2e-06
7 pVTA gene expression Dcaf7 0.03 0.02 8.4e-03 -0 0.01 -0 -0 5.1e-01 4.6e-02 4.8e-01 6.5e-01
8 NAcc mRNA stability Dcaf7 0.05 0.02 5.3e-09 0.06 0.06 0.06 0.06 9.2e-10 5.2e-09 3.2e-09 1.4e-09
9 Brain gene expression Dcaf7 0.04 0.03 1.3e-03 0.03 0.02 0.03 0.03 5.5e-04 2.7e-03 6.8e-04 9.9e-04
10 IC mRNA stability Dcaf7 0.12 0.06 1.2e-04 0.08 0.07 0.04 0.07 2.3e-04 6.0e-04 5.5e-03 6.8e-04
11 NAcc gene expression Dcaf7 0.01 0.01 6.6e-03 0.01 0.01 0 0.01 2.9e-02 2.7e-03 2.0e-01 3.3e-02
12 Brain mRNA stability Dcaf7 0.12 0.05 1.1e-07 0.05 0.07 0.08 0.09 1.1e-05 7.9e-07 3.3e-08 1.3e-08
13 BLA gene expression Dcaf7 0.05 0.04 5.6e-03 0.08 0.01 0.03 0.04 6.6e-05 1.3e-01 1.7e-02 3.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.22.27.81.0-2.02.01.0-1.01.2-0.8-2.20.7-0.5-0.52.8-1.2
Area under the delay curve0.20.30.80.4-0.10.20.0-0.00.6-0.8-0.70.3-0.4-0.80.90.2
BMI with tail1.34.512.02.4-0.60.92.0-1.91.3-2.9-1.52.1-2.3-3.5-0.13.1
BMI without tail1.68.418.83.1-1.42.02.9-2.92.3-3.8-2.73.2-3.0-4.31.23.1
Body weight3.816.430.84.6-2.73.34.0-3.93.7-5.1-3.93.6-3.9-5.63.04.6
Weight adjusted by age0.20.71.6-0.61.2-1.2-1.01.0-0.70.31.1-0.70.50.2-0.90.3
Bone surface4.89.419.43.2-3.93.92.7-2.73.2-2.7-3.82.2-2.1-2.44.40.9
Bone volume3.77.514.42.7-3.53.52.3-2.42.8-2.5-3.62.0-1.9-2.23.80.5
Breakpoint value in progressive ratio session0.10.21.10.2-0.71.00.5-0.60.50.3-0.50.2-0.20.5-0.1-0.3
Number of licking bursts0.00.00.10.3-0.20.1-0.10.10.2-0.10.1-0.0-0.1-0.10.30.2
Context. condit. distance diff. score0.30.42.0-0.60.9-0.9-0.40.4-0.20.20.90.2-0.00.1-1.40.4
Locomotion velocity, session 11.01.24.40.6-1.21.20.9-1.01.0-0.9-1.31.1-0.4-0.82.1-0.0
Locomotion distance, session 10.20.22.2-0.30.1-0.1-0.10.10.1-0.3-0.2-0.0-0.1-0.31.5-0.6
Locomotion velocity, session 20.30.41.20.1-1.11.00.8-0.80.70.3-0.40.3-0.20.60.6-0.4
Locomotion distance, session 20.20.20.8-0.90.4-0.4-0.30.30.00.50.6-0.30.10.70.2-0.8
Locomotion velocity, session 30.20.20.5-0.50.2-0.3-0.50.5-0.50.50.4-0.70.40.50.3-0.3
Locomotion distance, session 30.10.10.50.3-0.40.3-0.00.00.20.0-0.1-0.60.00.10.70.0
Stereotopy head waving bouts, day 30.30.41.3-0.70.1-0.1-0.60.6-0.60.6-0.1-0.20.90.60.2-1.1
Stereotopy head waving duration, day 30.30.41.0-1.00.5-0.5-0.80.8-0.50.40.3-0.00.80.5-0.8-0.7
Locomotion velocity, session 70.50.51.0-0.90.6-0.6-0.60.6-0.80.80.5-0.80.50.8-0.4-1.0
Locomotion distance, session 70.20.31.1-0.70.7-0.7-0.30.3-0.40.20.6-0.4-0.20.3-1.1-0.5
Stereotopy head waving bouts, day 70.70.82.0-1.00.2-0.3-0.80.8-0.61.10.5-0.71.31.30.2-1.4
Stereotopy head waving duration, day 71.92.45.2-1.80.7-0.8-1.41.4-1.02.01.2-1.22.02.3-0.5-2.3
Locomotion velocity, session 80.40.52.00.5-0.20.20.6-0.60.9-0.60.00.9-0.5-0.7-0.11.4
Locomotion distance, session 80.20.30.9-0.90.6-0.6-0.10.10.30.30.80.3-0.50.4-1.0-0.4
Degree of sensitization distance0.30.31.6-0.50.6-0.50.1-0.10.1-0.50.30.6-0.5-0.5-1.20.2
Degree of sensitization stereotypy1.11.22.8-1.10.6-0.7-1.00.9-0.91.61.1-1.11.41.7-0.0-1.4
Conditioned locomotion0.30.41.6-0.1-0.30.40.7-0.70.7-0.5-0.50.6-1.3-0.3-0.5-0.5
Cocaine response after cond. corrected0.20.30.70.40.5-0.5-0.70.7-0.5-0.30.4-0.60.7-0.50.00.9
Cocaine response after cond. not corrected0.20.41.20.50.0-0.0-0.70.7-0.50.30.3-0.91.10.20.90.4
Cocaine response before conditioning0.40.51.8-0.1-0.70.7-0.10.0-0.00.8-0.2-0.30.41.11.3-0.9
Saline control response1.31.83.61.2-1.11.11.8-1.81.3-1.0-0.91.9-1.9-0.9-0.41.2
Bone: connectivity density1.82.98.01.3-2.32.31.3-1.41.6-1.1-2.31.2-1.1-0.72.8-1.0
Bone: cortical apparent density3.65.79.8-3.12.5-2.4-2.62.5-2.42.21.8-2.41.92.2-1.6-2.9
Bone: cortical area1.62.66.42.1-1.81.81.1-1.11.0-1.6-2.10.5-0.9-1.72.51.3
Bone: cortical porosity9.810.721.54.6-4.24.13.2-3.22.5-2.3-3.31.9-1.6-2.44.13.3
Bone: cortical porosity8.29.118.54.3-3.63.62.8-2.72.3-2.5-3.11.5-1.4-2.63.83.5
Bone: cortical thickness3.25.412.8-1.71.9-1.9-2.82.8-3.32.21.3-3.63.01.70.6-1.7
Bone: cortical thickness2.83.47.7-1.31.2-1.1-1.81.8-2.42.11.0-2.82.32.00.2-2.2
Bone: cortical tissue density3.55.69.5-3.12.4-2.4-2.52.5-2.42.31.8-2.31.92.2-1.6-2.9
Condit. Reinf. active minus inactive responses2.73.14.81.9-2.22.22.0-2.01.8-1.4-1.91.8-1.6-1.21.41.0
Condit. Reinf. active-inactive response ratio1.11.12.21.2-1.41.51.2-1.21.1-0.7-1.21.1-0.9-0.50.90.4
Condit. Reinf. active responses3.03.95.21.7-2.32.32.3-2.32.3-1.8-2.12.2-2.2-1.51.10.9
Condit. Reinf. inactive responses0.91.22.20.5-1.01.01.1-1.11.4-1.3-1.21.3-1.5-1.10.50.3
Incentive salience index mean2.43.15.91.8-2.42.42.0-2.01.9-1.2-2.11.4-1.4-0.81.90.5
Condit. Reinf. lever presses0.50.71.90.5-1.41.31.0-1.11.0-0.0-1.00.1-0.20.31.0-0.6
Condit. Reinf. active minus inactive responses4.87.512.82.7-3.63.62.6-2.73.3-2.4-3.22.7-2.1-1.82.71.0
Condit. Reinf. active-inactive response ratio2.94.58.82.3-3.02.92.1-2.12.3-1.6-2.52.0-1.2-1.22.50.5
Condit. Reinf. active responses6.08.713.02.7-3.63.63.1-3.13.5-2.7-3.33.1-2.9-2.22.21.2
Condit. Reinf. inactive responses1.42.14.90.8-1.41.41.6-1.71.6-1.5-1.51.8-2.2-1.2-0.10.5
Condit. Reinf. lever presses1.82.54.41.6-2.12.11.9-1.91.7-1.2-1.81.5-1.4-0.91.10.7
Condit. Reinf. lever reinforcers received5.67.811.92.6-3.43.42.9-3.03.2-2.6-3.23.0-2.7-2.12.11.2
Conditioned reinforcement - actives0.20.82.00.9-0.30.21.0-0.90.7-1.3-0.31.2-1.4-1.30.30.6
Conditioned reinforcement - inactives0.51.52.51.5-0.90.91.4-1.30.9-1.4-1.01.4-1.5-1.60.90.8
Conditioned locomotion2.63.96.52.2-1.81.62.3-2.21.6-2.2-1.72.2-2.5-2.21.60.9
Patch foraging indifference point 0 sec2.05.59.81.8-2.32.32.4-2.42.7-2.6-2.53.1-3.1-2.20.90.8
Patch foraging indifference point AUC0.30.81.60.7-0.50.60.9-0.91.3-1.1-0.71.1-1.2-1.10.70.6
Delay disc. indifference point, 0s delay0.40.51.8-0.90.6-0.6-0.90.8-0.10.40.3-0.50.30.60.5-1.4
Delay disc. indifference point, 16s delay0.81.12.71.3-0.50.70.7-0.71.0-1.5-1.10.8-0.9-1.60.91.4
Delay disc. indifference point, 2s delay0.50.61.70.0-0.70.70.1-0.11.3-0.9-1.20.6-0.6-0.61.1-0.7
Delay disc. indifference point, 24s delay1.32.15.21.3-0.70.81.2-1.21.5-2.1-1.41.4-1.4-2.31.31.2
Delay disc. indifference point, 4s delay0.30.30.7-0.00.4-0.3-0.80.8-0.70.40.3-0.90.70.40.8-0.2
Delay disc. indifference point, 8s delay0.10.10.4-0.30.2-0.0-0.40.40.2-0.2-0.5-0.10.0-0.10.6-0.4
Indifference point function ln k0.10.20.6-0.5-0.00.1-0.50.5-0.60.4-0.1-0.60.70.5-0.1-0.8
Indifference point function log k0.10.20.6-0.5-0.00.1-0.50.5-0.60.4-0.1-0.60.70.5-0.1-0.8
Patch foraging total patch changes 0 sec2.16.210.42.1-2.52.42.5-2.62.8-2.7-2.73.2-3.2-2.41.21.2
Patch foraging total patch changes 12 sec3.24.38.81.3-1.91.82.3-2.43.0-2.1-1.82.8-2.9-1.60.60.1
Patch foraging total patch changes 18 sec1.63.85.82.1-1.91.82.1-2.12.1-1.9-1.72.4-2.2-1.80.91.9
Patch foraging total patch changes 24 sec1.34.46.11.7-2.32.32.0-2.02.4-2.2-2.52.5-2.4-1.91.80.8
Patch foraging total patch changes 6 sec2.03.44.81.7-1.91.91.9-1.92.0-1.9-2.02.2-2.2-1.71.20.9
Patch foraging time to switch 0 sec0.10.51.7-0.30.3-0.4-0.50.4-1.01.00.7-1.01.31.0-0.3-0.2
Patch foraging water rate 0 sec0.83.04.71.5-1.51.61.8-1.81.7-2.1-2.01.8-2.2-2.11.20.7
Patch foraging water rate 12 sec0.20.72.1-0.10.6-0.5-1.11.2-1.20.40.4-1.41.20.00.50.2
Patch foraging water rate 18 sec0.10.31.5-0.2-0.40.5-0.30.30.10.1-0.5-0.50.20.31.1-1.2
Patch foraging water rate 24 sec0.10.10.3-0.10.2-0.1-0.40.4-0.0-0.00.2-0.50.1-0.10.2-0.5
Patch foraging water rate 6 sec0.20.31.80.4-0.60.70.1-0.10.0-0.4-1.0-0.0-0.3-0.41.3-0.6
Seeking ratio, delayed vs. immediate footshock0.10.10.30.10.5-0.30.2-0.1-0.3-0.10.20.10.0-0.4-0.4-0.2
Distance traveled before self-admin0.20.40.80.50.2-0.1-0.70.7-0.50.30.4-0.90.90.20.90.9
Distance traveled after self-admin0.10.10.50.4-0.00.2-0.30.40.40.20.2-0.50.00.20.40.7
Extensor digitorum longus weight1.55.818.5-1.63.6-3.7-1.81.8-2.70.82.9-1.11.30.0-4.31.5
Bone: elastic displacement1.31.64.4-0.80.9-0.9-1.41.4-1.61.30.8-1.92.11.10.5-0.6
Bone: elastic work0.40.53.70.8-0.50.50.2-0.1-0.4-0.1-0.7-0.90.7-0.31.90.3
Bone: endosteal estimation12.831.338.36.1-6.26.16.0-6.06.1-5.4-5.45.8-5.8-4.94.14.4
Bone: endosteal perimeter14.435.345.46.7-6.16.16.0-6.06.6-6.2-5.65.9-5.7-6.04.35.6
Epididymis fat weight0.31.43.21.0-0.70.61.1-1.11.0-1.6-0.91.5-1.3-1.70.11.8
Delta time in closed arm before/after self-admin0.30.30.7-0.40.3-0.2-0.40.4-0.50.50.2-0.80.60.50.8-0.5
Delta time in open arm before/after self-admin0.60.75.1-1.00.7-0.7-0.00.00.1-0.10.40.8-0.80.0-2.3-0.6
Diff in mean of infusions in LGA sessions1.32.43.1-1.71.6-1.6-1.41.3-1.41.81.6-1.31.61.7-1.7-1.2
Delay discount exponential model param0.30.40.9-0.50.2-0.3-0.20.2-0.81.00.8-0.50.61.0-0.9-0.4
Extinction: sum of active levers before priming0.20.32.6-0.60.3-0.20.0-0.00.4-0.10.10.6-0.80.1-1.6-0.4
Active lever presses in extinction session 61.71.72.91.4-1.11.61.5-1.51.2-1.2-1.51.7-1.3-1.20.40.8
Bone: final force0.91.46.61.5-1.31.30.5-0.50.8-1.0-1.40.1-0.5-1.12.60.7
Bone: final moment0.91.57.61.6-1.41.40.5-0.50.7-1.0-1.4-0.0-0.5-1.02.80.7
Food consumed during 24 hour testing period1.83.76.01.6-1.31.32.0-2.02.0-2.2-1.52.4-2.4-2.30.02.3
Glucose1.01.63.3-0.61.8-1.5-1.41.5-1.20.81.5-1.31.80.5-1.00.7
Heart weight0.40.63.90.40.4-0.4-0.70.8-0.4-0.70.0-0.60.4-1.10.52.0
Delay discount hyperbolic model param0.30.40.9-0.50.3-0.4-0.20.2-0.80.90.8-0.50.60.9-0.9-0.3
Intermittent access intake day 1-15 change0.00.20.50.50.3-0.50.2-0.2-0.4-0.00.7-0.1-0.1-0.2-0.60.6
Intermittent access intake escalation0.10.41.51.1-0.2-0.00.7-0.60.2-0.60.20.4-0.5-0.8-0.41.2
Intermittent access intake escalation 20.30.51.51.1-0.30.20.9-0.80.3-0.6-0.00.5-0.7-0.8-0.11.2
Intermitt. access day 1 inactive lever presses0.33.85.91.9-2.32.32.4-2.41.8-1.6-2.22.2-2.3-1.41.30.6
Intermitt. access day 15 inactive lever presses0.42.34.41.7-1.51.42.1-2.10.6-1.3-1.61.8-1.9-1.21.00.0
Intermitt. access escalation Index0.82.43.9-1.21.6-1.6-2.02.0-1.41.41.7-1.72.01.3-1.2-0.1
Intermittent access day 1 total infusions0.31.01.80.8-1.01.01.0-1.01.2-1.2-0.81.3-1.3-1.10.60.2
Intermittent access day 15 total infusions1.02.34.91.7-0.90.71.6-1.51.3-2.0-0.81.9-2.0-2.20.21.7
Intermittent access terminal intake (last 3 days)2.03.56.12.0-1.41.22.1-2.01.8-2.4-1.12.3-2.5-2.40.61.5
Intermittent access total infusions2.42.85.01.5-1.31.11.8-1.71.9-2.1-1.12.2-2.2-2.10.61.0
Intermittent access day 1 locomotion2.75.05.82.3-2.32.32.4-2.32.0-2.3-2.22.4-2.4-2.32.21.4
Intermittent access day 15 total locomotion1.55.98.62.4-2.22.12.7-2.72.6-2.7-2.12.9-2.8-2.71.61.5
Intermittent access total locomotion6.67.910.82.7-2.82.63.2-3.22.9-3.0-2.63.3-3.2-2.92.21.4
Intermittent access standard deviation0.10.71.50.7-0.70.71.2-1.10.6-0.7-0.61.0-1.2-0.70.30.3
Left kidney weight0.10.41.8-0.10.5-0.1-0.80.8-0.30.1-0.1-1.11.00.01.4-0.3
Right kidney weight0.10.65.10.60.30.3-0.40.40.2-0.5-0.5-0.60.7-0.72.30.3
Cocaine induced anxiety0.20.41.40.00.2-0.1-0.70.7-0.70.60.1-1.00.90.51.20.5
Post-drug Anxiety0.50.61.4-0.00.5-0.3-0.90.9-0.90.60.3-1.21.10.41.10.7
Baseline Anxiety0.00.10.3-0.10.5-0.4-0.20.3-0.50.10.2-0.20.4-0.10.00.2
Tail length1.89.614.63.2-2.93.53.4-3.43.1-3.0-3.62.8-2.7-2.83.81.6
Length with tail1.98.513.13.0-2.42.92.8-2.83.4-3.3-3.12.4-2.2-3.23.62.4
Length without tail0.10.71.70.7-0.10.40.5-0.51.0-1.2-0.50.4-0.5-1.31.21.3
Times rat made contact with spout0.80.91.20.9-1.11.01.0-1.01.0-0.9-1.00.7-0.9-0.90.90.9
Lifetime Intake2.73.45.51.8-1.61.42.0-2.02.0-2.3-1.42.4-2.3-2.20.61.0
Liver weight, left3.45.910.72.4-2.83.32.5-2.53.2-2.0-2.71.8-1.5-1.73.01.0
Liver weight, right0.81.43.5-0.50.6-0.3-1.11.0-1.10.90.2-1.91.70.81.8-1.7
Locomotor activity0.30.51.70.5-0.60.30.9-0.90.9-0.5-0.11.3-1.3-0.30.20.0
Locomotor testing distance0.61.53.11.3-1.10.81.6-1.51.1-0.9-0.51.8-1.7-0.80.61.2
Locomotor testing rearing0.41.53.11.3-1.10.81.8-1.70.8-0.3-0.21.7-1.8-0.2-0.11.5
Locomotion in novel chamber0.20.31.20.3-0.2-0.0-0.30.4-0.20.10.4-0.81.0-0.11.1-0.5
Locomotion in novel chamber post-restriction0.62.03.71.4-1.31.30.8-0.81.9-1.8-1.51.5-1.4-1.71.11.2
Fecal boli incidents, locomotor time 10.10.20.70.40.3-0.20.1-0.10.3-0.50.10.2-0.5-0.6-0.10.9
Change in fecal boli incidents, locomotor task0.20.20.8-0.30.7-0.6-0.30.3-0.5-0.30.1-0.40.2-0.4-0.90.3
Time >=10cm from walls, locomotor time 12.22.73.7-1.31.7-1.6-1.91.9-1.71.71.9-1.91.81.5-1.6-0.4
Bouts of movement, locomotor time 10.20.20.6-0.80.4-0.4-0.40.4-0.70.50.1-0.40.50.4-0.4-0.7
Total resting periods, locomotor time 10.20.30.7-0.80.4-0.4-0.50.5-0.80.50.1-0.50.60.3-0.1-0.8
Rest time, locomotor task time 10.10.20.9-0.6-0.10.0-0.20.2-0.30.40.0-0.10.30.60.3-0.9
Distance moved, locomotor task time 10.10.31.00.7-0.40.40.6-0.60.2-0.7-0.60.4-0.4-0.8-0.01.0
Vertical activity count, locomotor time 10.00.30.60.7-0.60.50.5-0.50.2-0.7-0.60.1-0.4-0.8-0.00.3
Time >=10cm from walls, locomotor time 20.10.30.60.5-0.3-0.1-0.20.2-0.80.70.6-0.70.60.70.30.5
Bouts of movement, locomotor time 20.10.20.7-0.20.4-0.4-0.40.4-0.80.40.1-0.80.60.2-0.60.5
Total resting periods, locomotor time 20.10.41.2-0.40.6-0.5-0.60.6-1.00.60.3-1.10.80.5-0.70.5
Rest time, locomotor task time 21.72.84.9-1.91.9-1.4-2.22.2-1.51.51.3-1.71.81.4-1.5-0.9
Distance moved, locomotor task time 20.30.41.30.7-1.10.81.0-1.00.1-0.1-0.60.4-0.2-0.10.6-0.2
Vertical activity count, locomotor time 20.92.14.51.4-2.01.72.1-2.11.0-0.9-1.51.5-1.3-0.80.8-0.3
Light reinforcement 10.10.51.4-0.1-0.50.60.4-0.50.7-0.7-1.11.1-1.2-0.4-0.3-0.4
Light reinforcement 20.30.71.70.1-0.90.80.5-0.60.7-0.8-1.30.8-0.9-0.50.7-1.1
Bone: marrow area12.430.337.26.0-6.16.05.9-5.96.0-5.3-5.35.7-5.6-4.84.14.3
Bone: maximum diameter4.99.814.23.8-3.53.52.8-2.83.2-3.3-3.42.5-2.6-3.23.22.5
Bone: maximum force1.63.17.82.1-1.61.61.1-1.11.4-2.1-1.90.8-1.1-2.22.81.8
Bone: maximum moment1.73.28.92.2-1.81.71.1-1.11.3-2.0-2.00.7-1.1-2.13.01.7
Mean time between licks in bursts0.10.73.70.70.2-0.30.2-0.20.3-1.3-0.10.6-0.8-1.6-0.01.9
Mean num. licks in bursts0.10.30.50.2-0.40.40.7-0.70.4-0.6-0.70.6-0.4-0.7-0.10.4
Cd content in liver4.04.46.9-2.42.5-2.4-1.92.0-2.02.02.4-1.71.71.9-2.6-1.4
Co content in liver1.51.72.9-1.31.5-1.6-1.21.2-1.01.41.7-0.91.31.3-1.6-0.7
Cu content in liver0.40.40.80.6-0.90.90.8-0.80.6-0.5-0.90.6-0.4-0.30.6-0.2
Fe content in liver0.20.31.2-0.3-0.20.2-0.10.10.10.80.3-0.80.61.10.1-0.6
K content in liver0.20.21.3-0.1-0.60.50.2-0.31.1-0.3-0.30.4-0.50.20.2-0.5
Mg content in liver1.21.35.4-1.80.7-0.7-0.80.7-0.11.20.7-0.50.51.6-1.1-2.3
Mn content in liver1.01.28.3-1.5-0.10.0-0.70.60.20.90.0-0.50.31.50.4-2.9
Na content in liver0.40.41.60.1-0.90.90.5-0.61.3-0.1-0.60.6-0.20.40.0-0.7
Rb content in liver4.45.27.5-2.51.8-1.9-2.42.4-1.72.62.1-2.72.62.7-1.1-2.5
Se content in liver1.11.32.2-1.51.1-1.1-1.51.4-0.40.81.0-1.01.20.9-1.4-0.7
Sr content in liver1.21.02.01.4-1.01.00.8-0.80.8-1.0-1.10.6-0.5-1.11.21.2
Zn content in liver0.30.41.2-0.50.5-0.4-0.80.8-0.50.50.5-0.81.10.5-0.1-0.6
Bone: minimum diameter13.626.032.45.7-5.25.25.1-5.05.2-5.4-5.25.0-4.9-5.34.14.9
Time in familiar zone, hab. session 10.60.61.60.5-0.10.10.8-0.80.9-0.9-0.11.1-1.0-0.9-0.51.3
Time in novel zone, hab. session 10.70.81.9-0.60.4-0.3-1.01.0-1.41.10.3-1.21.31.00.1-1.0
Total zone transitions, hab. session 10.10.20.60.10.3-0.30.2-0.20.2-0.50.20.4-0.4-0.60.80.5
Total locomotion distance, hab. session 10.60.95.10.8-0.90.80.9-0.90.6-0.8-1.00.5-0.6-0.82.30.0
Locomotion velocity, hab. session 10.91.25.00.9-1.00.91.1-1.11.0-1.1-1.10.8-1.0-1.02.20.2
Time in familiar zone, hab. session 20.70.82.10.6-0.40.31.1-1.01.2-0.8-0.11.4-1.2-0.7-0.61.1
Time in novel zone, hab. session 20.80.81.7-0.40.3-0.2-1.11.0-1.20.7-0.1-1.31.20.61.1-1.3
Total zone transitions, hab. session 20.10.10.4-0.60.5-0.60.0-0.00.3-0.00.60.4-0.40.00.30.0
Total locomotion distance, hab. session 20.20.31.0-0.50.1-0.10.5-0.50.6-0.4-0.21.0-0.9-0.30.5-0.7
Locomotion velocity, hab. session 20.20.30.7-0.60.2-0.20.3-0.40.6-0.5-0.10.9-0.8-0.30.5-0.6
Novel to familiar place preference ratio0.40.61.10.9-0.80.90.5-0.50.5-0.9-1.10.2-0.3-1.00.51.0
Novelty place preference0.20.30.60.6-0.70.70.3-0.30.3-0.5-0.8-0.00.0-0.60.30.7
Time in novel zone, NPP test0.20.20.50.5-0.60.70.2-0.20.2-0.3-0.7-0.20.2-0.40.40.6
Total zone transitions, NPP test0.20.20.8-0.90.5-0.6-0.30.20.3-0.10.40.3-0.3-0.00.7-0.8
Total locomotion distance, NPP test0.40.52.4-0.0-0.40.40.6-0.60.7-0.5-0.60.9-0.8-0.31.5-0.9
Locomotion velocity, NPP test0.30.41.0-0.20.0-0.00.4-0.50.5-0.8-0.41.0-1.0-0.70.8-0.5
Intraocular pressure1.11.75.61.4-0.30.31.2-1.10.3-2.0-0.91.5-1.4-2.40.21.8
Delta distance traveled before/after self-admin0.10.10.4-0.50.10.1-0.20.20.20.60.0-0.3-0.10.7-0.6-0.4
Delta ambulatory time before/after self-admin0.00.10.4-0.3-0.10.10.2-0.10.50.1-0.20.0-0.60.2-0.1-0.4
Parametrial fat weight0.30.83.30.7-1.01.20.4-0.50.7-0.8-1.40.1-0.3-0.71.8-0.3
Pavlov. Cond. lever latency1.72.24.1-1.52.0-2.0-1.71.7-1.61.01.7-0.80.80.8-1.9-0.6
Pavlov. Cond. magazine entry latency3.64.68.32.0-2.82.92.4-2.42.4-1.6-2.71.8-1.4-1.32.30.5
Pavlov. Cond. change in total contacts2.83.15.81.7-2.42.42.1-2.21.8-1.1-2.21.4-1.2-0.81.70.4
Pavlov. Cond. index score3.03.86.91.9-2.62.62.2-2.22.2-1.5-2.41.4-1.2-1.22.00.7
Pavlov. Cond. latency score2.43.15.61.7-2.32.42.0-2.02.1-1.3-2.11.3-1.1-1.01.70.7
Pavlov. Cond. lever contacts2.22.75.11.7-2.32.21.9-2.01.7-1.0-1.90.9-0.9-0.82.00.7
Pavlov. Cond. magazine entry number2.53.26.2-1.52.5-2.5-2.02.1-2.01.22.3-1.51.30.8-1.8-0.0
Pavlov. Cond. intertrial magazine entries1.11.44.20.4-0.20.20.9-0.91.1-1.6-0.61.8-2.1-1.5-0.91.1
Pavlov. Cond. lever-magazine prob. diff.3.23.97.32.0-2.72.72.2-2.22.2-1.5-2.51.4-1.1-1.32.10.7
Pavlov. Cond. response bias4.55.611.12.2-3.33.32.5-2.62.5-1.6-3.11.5-1.5-1.13.10.1
Pavlov. Cond. lever latency0.30.40.9-0.70.9-0.9-0.70.7-1.00.50.7-0.70.70.3-0.3-0.3
Pavlov. Cond. magazine entry latency1.92.74.2-1.31.7-1.8-1.91.9-1.41.62.0-2.01.71.5-1.4-0.3
Pavlov. Cond. change in total contacts0.20.41.60.2-0.70.60.7-0.71.2-0.3-0.31.0-0.90.0-0.50.2
Pavlov. Cond. index score0.00.00.10.1-0.20.1-0.10.10.30.20.3-0.20.10.3-0.30.3
Pavlov. Cond. latency score0.10.10.20.1-0.10.0-0.30.30.10.30.4-0.50.30.4-0.20.3
Pavlov. Cond. lever contacts0.20.30.60.5-0.70.70.6-0.60.8-0.4-0.50.6-0.6-0.20.00.1
Pavlov. Cond. magazine entry number2.93.85.41.7-1.92.02.3-2.31.8-2.1-2.32.2-2.0-2.01.30.9
Pavlov. Cond. intertrial magazine entries8.318.122.04.4-4.24.24.7-4.74.2-4.6-4.74.7-4.0-4.43.13.2
Pavlov. Cond. lever-magazine prob. diff.0.00.10.10.0-0.0-0.0-0.30.30.20.30.4-0.30.20.4-0.30.2
Pavlov. Cond. response bias0.00.00.20.0-0.20.1-0.00.00.40.00.10.1-0.20.2-0.3-0.0
Time in closed arm before self-admin0.10.10.50.2-0.40.70.0-0.0-0.20.5-0.3-0.10.60.40.20.0
Time in closed arm after self-admin0.60.62.0-0.60.4-0.2-0.90.9-0.71.10.5-1.21.40.9-0.0-0.2
Time in open arm before self-admin0.81.02.30.10.8-1.0-1.21.2-1.10.71.0-1.51.40.31.00.4
Time in open arm after self-admin0.30.30.80.20.3-0.50.3-0.30.3-0.80.20.8-0.8-0.9-0.70.6
Bone: periosteal estimation8.720.826.95.2-5.25.24.6-4.54.6-4.5-4.94.1-4.3-4.24.43.4
Bone: periosteal perimeter5.310.517.64.2-3.63.62.8-2.83.3-3.3-3.42.2-2.3-3.33.43.4
Bone: post-yield work1.62.75.42.2-1.61.61.5-1.41.5-1.8-1.41.2-1.4-1.91.32.3
Progressive ratio test 1 active lever presses2.03.55.61.9-1.81.72.0-1.91.9-2.2-1.82.2-2.4-2.11.01.0
Progressive ratio test 1 breakpoint2.33.96.21.9-1.91.92.1-2.12.0-2.3-2.02.3-2.5-2.21.00.9
Progressive ratio test 1 inactive lever presses1.64.26.42.1-2.11.92.3-2.22.1-2.3-1.92.5-2.5-2.11.01.0
Progressive ratio test 2 active lever presses4.97.010.32.9-2.52.32.7-2.62.7-3.2-2.52.8-3.2-3.11.61.8
Progressive ratio test 2 breakpoint5.97.611.03.0-2.62.42.8-2.72.8-3.3-2.62.9-3.3-3.31.62.1
Progressive ratio test 2 inactive lever presses1.34.06.41.9-1.71.62.1-2.11.8-2.5-1.92.5-2.5-2.41.21.0
Incentive Sensitization - Responses1.64.56.92.5-2.01.82.0-2.02.3-2.6-1.91.9-2.2-2.61.42.1
Incentive Sensitization - Breakpoint2.04.56.72.5-2.01.82.0-2.02.2-2.6-1.81.9-2.2-2.61.32.1
Sum of active levers in priming session hrs 5-61.00.95.0-0.91.0-1.0-0.60.6-0.60.71.1-0.30.20.8-2.2-0.9
Progressive ratio0.10.31.50.2-0.10.7-0.10.11.0-0.6-0.60.3-0.1-0.6-0.51.2
Food seeking constrained by brief footshock2.53.16.01.7-1.51.72.1-2.12.2-1.5-1.22.4-1.8-1.30.71.5
Seeking ratio, punishment vs. effort0.61.22.71.2-1.20.71.6-1.60.7-0.8-0.61.5-1.3-0.71.20.2
Retroperitoneal fat weight0.42.02.61.2-1.31.31.5-1.51.2-1.5-1.61.6-1.4-1.51.61.0
Reaction time number correct0.10.41.3-0.40.8-0.7-1.11.1-0.5-0.00.4-0.70.6-0.2-0.10.2
Reaction time mean minus median0.00.30.9-0.30.6-0.6-0.40.4-0.90.60.5-0.20.50.5-0.0-0.8
Reaction time mean minus median AUC0.21.62.0-1.31.4-1.3-1.41.4-1.41.31.2-0.91.41.2-0.3-1.3
Reaction time num false alarms2.74.76.72.4-2.32.32.1-2.12.6-2.3-2.12.0-1.9-2.12.01.7
Reaction time num false alarms AUC2.25.17.72.4-2.52.52.2-2.22.8-2.3-2.42.1-2.0-2.12.31.1
Reaction time trials correct on left0.10.41.3-0.40.8-0.7-1.11.1-0.5-0.00.4-0.70.6-0.2-0.10.2
Reaction time trials on left0.10.41.2-0.30.7-0.6-1.11.1-0.5-0.10.3-0.70.6-0.30.00.1
Reaction time mean0.71.53.2-1.20.8-0.9-1.11.1-1.41.61.1-1.01.31.8-0.3-1.8
Reaction time mean AUC0.92.24.5-1.51.0-1.1-1.21.2-1.72.01.4-1.11.52.1-0.7-2.0
Median of all reaction times1.11.63.8-1.30.8-0.8-1.11.1-1.41.71.1-1.11.31.9-0.4-1.7
Reaction time omissions0.20.41.60.5-0.50.70.4-0.4-0.2-0.3-0.90.4-0.1-0.31.2-0.9
Reaction time false alarm rate3.24.46.22.2-2.52.52.4-2.42.5-1.9-2.11.9-1.8-1.61.81.0
Reaction time premature initiation rate1.01.52.31.2-1.11.21.2-1.20.9-1.3-1.51.4-1.5-1.31.01.3
Reaction time premature initiations0.31.01.81.0-0.60.70.6-0.60.8-1.3-1.21.1-1.2-1.31.01.3
Std. dev. reaction times0.20.82.5-0.80.7-0.6-0.60.6-1.11.10.7-0.60.91.1-0.0-1.6
Reaction time trials completed0.10.41.2-0.30.7-0.6-1.11.1-0.5-0.10.3-0.70.6-0.30.00.1
Reaction time trials AUC0.10.41.3-0.40.8-0.7-1.11.1-0.5-0.00.4-0.70.6-0.2-0.00.1
Run reversals in cocaine runway, females0.30.31.70.60.5-0.6-0.10.1-1.3-0.10.3-0.30.6-0.60.60.6
Run reversals in cocaine runway, males0.20.21.30.60.2-0.0-0.20.3-0.4-0.2-0.0-0.50.4-0.41.10.6
Latency to leave start box in cocaine runway0.20.20.70.00.4-0.4-0.40.4-0.90.40.5-0.60.50.30.4-0.2
Latency to leave start box in cocaine runway, F0.40.51.20.40.2-0.3-0.70.7-1.00.40.5-1.11.10.20.90.8
Latency to leave start box in cocaine runway, M0.30.32.4-0.40.1-0.10.2-0.3-0.10.30.20.4-0.60.6-0.3-1.6
Std. dev. time between licks in bursts0.10.10.7-0.30.4-0.50.0-0.0-0.3-0.10.30.1-0.3-0.2-0.80.3
Total sessions with >9 infusions0.30.41.10.7-0.10.00.5-0.50.2-0.9-0.10.7-0.8-1.0-0.60.8
Short access day 1 total inactive lever presses1.53.05.12.3-1.81.71.8-1.81.4-1.8-1.81.8-1.2-1.91.81.3
Short access day 10 total inactive lever presses0.00.20.70.4-0.20.10.6-0.6-0.2-0.6-0.50.7-0.9-0.60.10.2
Short access day 1 total infusions0.20.51.20.7-0.50.40.7-0.70.5-0.9-0.51.1-0.8-0.9-0.7-0.0
Short access day 10 total infusions1.93.25.51.9-1.61.42.1-2.11.7-2.1-1.42.3-2.1-2.00.41.0
Short access total infusions1.21.73.01.4-1.31.21.5-1.51.2-1.5-1.11.7-1.5-1.40.20.5
Short access day 1 locomotion1.62.66.11.8-1.21.01.7-1.71.0-2.2-1.41.8-2.0-2.50.61.0
Short access day 10 total locomotion1.77.010.32.6-2.82.73.2-3.22.5-2.5-2.73.1-2.9-2.41.91.3
Short access total locomotion2.43.75.22.2-1.81.72.3-2.21.4-2.1-1.82.1-2.1-2.31.11.4
One hour access (0.3 mA shock)1.21.42.41.6-1.10.91.2-1.21.2-1.5-0.81.2-1.3-1.40.51.3
Compulsive drug intake0.40.62.1-0.10.5-0.3-1.21.2-0.50.70.4-1.31.50.60.30.6
One hour access (shock baseline)0.61.63.81.0-1.00.71.6-1.61.2-1.5-0.71.6-2.0-1.40.20.0
Social response proportion0.20.30.50.20.7-0.7-0.40.4-0.5-0.30.6-0.70.5-0.7-0.30.6
Social responses0.10.10.20.30.0-0.10.3-0.30.3-0.40.20.2-0.4-0.5-0.10.1
Social time0.20.41.41.2-0.20.20.4-0.4-0.1-0.7-0.10.2-0.2-1.1-0.21.0
Soleus weight0.30.92.71.6-0.80.70.6-0.60.7-1.0-0.70.2-0.0-1.20.81.6
Bone: stiffness0.30.61.40.6-0.60.50.3-0.31.2-1.1-0.50.5-0.8-1.01.10.8
Tibialis anterior weight0.31.04.60.80.4-0.50.8-0.80.2-1.00.00.6-0.7-1.4-1.42.1
Time to tail flick, vehicle, before self-admin0.30.41.80.3-0.2-0.2-0.60.6-0.30.00.5-0.70.80.01.3-0.8
Time to tail flick, vehicle, after self-admin0.10.10.40.3-0.20.2-0.20.20.6-0.6-0.40.3-0.0-0.60.40.5
Time to tail flick, test, before self-admin0.20.20.6-0.20.1-0.1-0.10.1-0.40.80.6-0.40.70.7-0.20.1
Time to tail flick, test, after self-admin0.00.00.1-0.1-0.30.3-0.0-0.00.10.1-0.20.30.30.30.30.1
Delta time to tail flick, vehicle, before/after SA1.11.22.60.6-0.81.21.1-1.21.3-1.0-1.51.6-1.1-0.8-0.30.9
Delta time to tail flick, test, before/after SA0.00.10.1-0.3-0.10.0-0.30.30.4-0.1-0.10.2-0.00.10.2-0.4
Tibia length0.20.64.80.5-0.10.2-0.50.50.3-0.3-0.3-0.90.7-0.42.20.3
Ambulatory time before self-admin0.10.31.30.7-0.10.4-0.50.5-0.10.1-0.0-0.70.60.10.91.1
Ambulatory time after self-admin0.10.20.90.6-0.30.6-0.00.10.40.1-0.4-0.4-0.10.10.90.7
Bone: tissue strength1.31.42.3-1.31.4-1.4-1.51.5-1.00.91.3-1.41.20.8-0.2-0.4
Total heroin consumption0.30.41.20.5-1.11.10.6-0.61.0-0.1-0.50.5-0.30.30.5-0.1
Bone: trabecular number1.73.38.51.3-2.52.51.4-1.51.8-1.3-2.61.3-1.1-0.92.9-0.9
Bone: trabecular spacing0.91.36.2-0.71.5-1.5-0.60.6-0.60.61.7-0.20.10.4-2.51.1
Bone: trabecular thickness3.34.512.72.3-2.62.71.7-1.71.4-1.9-3.11.0-1.3-1.93.60.3
Bone: trabecular tissue density0.81.32.8-1.41.1-1.1-1.71.7-1.10.40.5-1.61.30.20.5-1.1
Water consumed over 24 hours0.10.10.70.2-0.50.40.3-0.30.2-0.2-0.5-0.1-0.2-0.30.80.2
Number of responses in last shaping day0.30.41.41.2-0.60.30.6-0.5-0.0-0.6-0.40.5-0.1-0.70.90.5