Hub : Genes

Dcaf7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Dcaf7 0.14 0.07 2.0e-06 0.09 0.12 0.14 0.13 1.6e-04 6.5e-06 2.2e-06 4.4e-06
2 PL mRNA stability Dcaf7 0.11 0.05 1.3e-08 0.09 0.07 0.07 0.08 1.0e-09 1.3e-08 1.5e-08 2.0e-09
3 Adipose gene expression Dcaf7 0.11 0.05 7.5e-12 0.09 0.08 0.08 0.08 5.9e-10 2.8e-09 2.4e-09 2.0e-09
4 Adipose mRNA stability Dcaf7 0.04 0.02 9.2e-06 0.03 0.04 0.04 0.04 4.3e-04 2.0e-05 8.6e-05 7.2e-05
5 PL gene expression Dcaf7 0.03 0.02 8.9e-05 0.04 0.04 0.04 0.04 3.7e-05 2.3e-05 4.5e-05 2.6e-05
6 Liver gene expression Dcaf7 0.04 0.02 6.3e-06 0.03 0.05 0.05 0.05 3.5e-04 5.6e-06 2.3e-06 4.2e-06
7 pVTA gene expression Dcaf7 0.03 0.02 8.4e-03 -0 0.01 -0 -0 5.1e-01 4.6e-02 4.8e-01 6.6e-01
8 NAcc mRNA stability Dcaf7 0.05 0.02 5.3e-09 0.06 0.06 0.06 0.06 9.2e-10 5.2e-09 3.2e-09 1.3e-09
9 Brain gene expression Dcaf7 0.04 0.03 1.3e-03 0.03 0.02 0.03 0.03 5.5e-04 2.7e-03 7.2e-04 1.1e-03
10 IC mRNA stability Dcaf7 0.12 0.06 1.2e-04 0.08 0.07 0.04 0.07 2.3e-04 6.0e-04 5.5e-03 6.9e-04
11 NAcc gene expression Dcaf7 0.01 0.01 6.6e-03 0.01 0.01 0 0.01 2.9e-02 2.7e-03 2.0e-01 3.4e-02
12 Brain mRNA stability Dcaf7 0.12 0.05 1.1e-07 0.05 0.07 0.08 0.09 1.1e-05 7.9e-07 3.3e-08 1.5e-08
13 BLA gene expression Dcaf7 0.05 0.04 5.6e-03 0.08 0.01 0.03 0.04 6.6e-05 1.3e-01 1.7e-02 3.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.32.27.8-1.02.0-2.01.0-1.0-1.2-0.82.2-0.70.5-0.52.81.2
Area under the delay curve0.20.30.8-0.40.1-0.20.0-0.0-0.6-0.80.7-0.30.4-0.80.9-0.2
BMI with tail1.34.512.0-2.40.6-0.92.0-1.9-1.3-2.91.5-2.12.3-3.5-0.1-3.1
BMI without tail2.78.418.8-3.11.4-2.02.9-2.9-2.3-3.82.7-3.23.0-4.31.2-3.1
Body weight3.816.430.8-4.62.7-3.34.0-3.9-3.7-5.13.9-3.63.9-5.63.0-4.6
Weight adjusted by age0.50.71.60.6-1.21.2-1.01.00.70.3-1.10.7-0.50.2-0.9-0.3
Bone surface5.29.419.4-3.23.9-3.92.7-2.7-3.2-2.73.8-2.22.1-2.44.4-0.9
Bone volume4.27.514.4-2.73.5-3.52.3-2.4-2.8-2.53.6-2.01.9-2.23.8-0.5
Breakpoint value in progressive ratio session0.20.21.1-0.20.7-1.00.5-0.6-0.50.30.5-0.20.20.5-0.10.3
Number of licking bursts0.00.00.1-0.30.2-0.1-0.10.1-0.2-0.1-0.10.00.1-0.10.3-0.2
Context. condit. distance diff. score0.30.42.00.6-0.90.9-0.40.40.20.2-0.9-0.20.00.1-1.4-0.4
Locomotion velocity, session 11.11.24.4-0.61.2-1.20.9-1.0-1.0-0.91.3-1.10.4-0.82.10.0
Locomotion distance, session 10.20.22.10.3-0.10.1-0.10.1-0.1-0.30.20.00.1-0.31.50.6
Locomotion velocity, session 20.40.41.2-0.11.1-1.00.8-0.8-0.70.30.4-0.30.20.60.60.4
Locomotion distance, session 20.20.20.80.9-0.40.4-0.30.3-0.00.5-0.60.3-0.10.70.20.8
Locomotion velocity, session 30.20.20.50.5-0.20.3-0.50.50.50.5-0.40.7-0.40.50.30.3
Locomotion distance, session 30.10.10.5-0.30.4-0.3-0.00.0-0.20.00.10.6-0.00.10.7-0.0
Stereotopy head waving bouts, day 30.30.41.30.7-0.10.1-0.60.60.60.60.10.2-0.90.60.21.1
Stereotopy head waving duration, day 30.30.41.01.0-0.50.5-0.80.80.50.4-0.30.0-0.80.5-0.80.7
Locomotion velocity, session 70.50.51.00.9-0.60.6-0.60.60.80.8-0.50.8-0.50.8-0.41.0
Locomotion distance, session 70.20.31.10.7-0.70.7-0.30.30.40.2-0.60.40.20.3-1.10.5
Stereotopy head waving bouts, day 70.70.82.01.0-0.20.3-0.80.80.61.1-0.50.7-1.31.30.21.4
Stereotopy head waving duration, day 72.02.45.21.8-0.70.8-1.41.41.02.0-1.21.2-2.02.3-0.52.3
Locomotion velocity, session 80.40.52.0-0.50.2-0.20.6-0.6-0.9-0.6-0.0-0.90.5-0.7-0.1-1.4
Locomotion distance, session 80.20.30.90.9-0.60.6-0.10.1-0.30.3-0.8-0.30.50.4-1.00.4
Degree of sensitization distance0.30.31.60.5-0.60.50.1-0.1-0.1-0.5-0.3-0.60.5-0.5-1.2-0.2
Degree of sensitization stereotypy1.11.22.81.1-0.60.7-1.00.90.91.6-1.11.1-1.41.7-0.01.4
Conditioned locomotion0.30.41.60.10.3-0.40.7-0.7-0.7-0.50.5-0.61.3-0.3-0.50.5
Cocaine response after cond. corrected0.20.30.7-0.4-0.50.5-0.70.70.5-0.3-0.40.6-0.7-0.50.0-0.9
Cocaine response after cond. not corrected0.30.41.2-0.5-0.00.0-0.70.70.50.3-0.30.9-1.10.20.9-0.4
Cocaine response before conditioning0.40.51.80.10.7-0.7-0.10.00.00.80.20.3-0.41.11.30.9
Saline control response1.41.83.6-1.21.1-1.11.8-1.8-1.3-1.00.9-1.91.9-0.9-0.4-1.2
Bone: connectivity density1.82.98.0-1.32.3-2.31.3-1.4-1.6-1.12.3-1.21.1-0.72.81.0
Bone: cortical apparent density4.25.79.83.1-2.52.4-2.62.52.42.2-1.82.4-1.92.2-1.62.9
Bone: cortical area1.72.66.4-2.11.8-1.81.1-1.1-1.0-1.62.1-0.50.9-1.72.5-1.3
Bone: cortical porosity9.910.721.5-4.64.2-4.13.2-3.2-2.5-2.33.3-1.91.6-2.44.1-3.3
Bone: cortical porosity8.49.118.5-4.33.6-3.62.8-2.7-2.3-2.53.1-1.51.4-2.63.8-3.5
Bone: cortical thickness3.35.412.81.7-1.91.9-2.82.83.32.2-1.33.6-3.01.70.51.7
Bone: cortical thickness2.93.47.71.3-1.21.1-1.81.82.42.1-1.02.8-2.32.00.22.2
Bone: cortical tissue density4.15.69.53.1-2.42.4-2.52.52.42.3-1.82.3-1.92.2-1.62.9
Condit. Reinf. active minus inactive responses2.83.14.8-1.92.2-2.22.0-2.0-1.8-1.41.9-1.81.6-1.21.4-1.0
Condit. Reinf. active-inactive response ratio1.11.12.2-1.21.4-1.51.2-1.2-1.1-0.71.2-1.10.9-0.50.9-0.4
Condit. Reinf. active responses3.13.95.2-1.72.3-2.32.3-2.3-2.3-1.82.1-2.22.2-1.51.1-0.9
Condit. Reinf. inactive responses1.01.22.2-0.51.0-1.01.1-1.1-1.4-1.31.2-1.31.5-1.10.5-0.3
Incentive salience index mean2.53.15.9-1.82.4-2.42.0-2.0-1.9-1.22.1-1.41.4-0.81.9-0.5
Condit. Reinf. lever presses0.50.71.9-0.51.4-1.31.0-1.1-1.0-0.01.0-0.10.20.31.00.6
Condit. Reinf. active minus inactive responses5.87.512.8-2.73.6-3.62.6-2.7-3.3-2.43.2-2.72.1-1.82.7-1.0
Condit. Reinf. active-inactive response ratio3.94.58.8-2.33.0-2.92.1-2.1-2.3-1.62.5-2.01.2-1.22.5-0.5
Condit. Reinf. active responses6.28.713.0-2.73.6-3.63.1-3.1-3.5-2.73.3-3.12.9-2.22.2-1.2
Condit. Reinf. inactive responses1.62.14.9-0.81.4-1.41.6-1.7-1.6-1.51.5-1.82.2-1.2-0.1-0.5
Condit. Reinf. lever presses1.82.54.4-1.62.1-2.11.9-1.9-1.7-1.21.8-1.51.4-0.91.1-0.7
Condit. Reinf. lever reinforcers received5.67.811.9-2.63.4-3.42.9-3.0-3.2-2.63.2-3.02.7-2.12.1-1.2
Conditioned reinforcement - actives0.50.82.0-0.90.3-0.21.0-0.9-0.7-1.30.3-1.21.4-1.30.3-0.6
Conditioned reinforcement - inactives1.01.52.5-1.50.9-0.91.4-1.3-0.9-1.41.0-1.41.5-1.60.9-0.8
Conditioned locomotion3.03.96.5-2.21.8-1.62.3-2.2-1.6-2.21.7-2.22.5-2.21.6-0.9
Patch foraging indifference point 0 sec3.05.59.8-1.82.3-2.32.4-2.4-2.7-2.62.5-3.13.1-2.20.9-0.8
Patch foraging indifference point AUC0.60.81.6-0.70.5-0.60.9-0.9-1.3-1.10.7-1.11.2-1.10.7-0.6
Delay disc. indifference point, 0s delay0.40.51.80.9-0.60.6-0.90.80.10.4-0.30.5-0.30.60.51.4
Delay disc. indifference point, 16s delay1.01.12.7-1.30.5-0.70.7-0.7-1.0-1.51.1-0.80.9-1.60.9-1.4
Delay disc. indifference point, 2s delay0.50.61.7-0.00.7-0.70.1-0.1-1.3-0.91.2-0.60.6-0.61.10.7
Delay disc. indifference point, 24s delay1.92.15.2-1.30.7-0.81.2-1.2-1.5-2.11.4-1.41.4-2.31.3-1.2
Delay disc. indifference point, 4s delay0.30.30.70.0-0.40.3-0.80.80.70.4-0.30.9-0.70.40.80.2
Delay disc. indifference point, 8s delay0.10.10.40.3-0.20.0-0.40.4-0.2-0.20.50.1-0.0-0.10.60.4
Indifference point function ln k0.10.20.60.50.0-0.1-0.50.50.60.40.10.6-0.70.5-0.10.8
Indifference point function log k0.10.20.60.50.0-0.1-0.50.50.60.40.10.6-0.70.5-0.10.8
Patch foraging total patch changes 0 sec3.36.210.4-2.12.5-2.42.5-2.6-2.8-2.72.7-3.23.2-2.41.2-1.2
Patch foraging total patch changes 12 sec3.34.38.8-1.31.9-1.82.3-2.4-3.0-2.11.8-2.82.9-1.60.6-0.1
Patch foraging total patch changes 18 sec2.53.85.8-2.11.9-1.82.1-2.1-2.1-1.91.7-2.42.2-1.80.9-1.9
Patch foraging total patch changes 24 sec2.64.46.1-1.72.3-2.32.0-2.0-2.4-2.22.5-2.52.4-1.91.8-0.8
Patch foraging total patch changes 6 sec2.23.44.8-1.71.9-1.91.9-1.9-2.0-1.92.0-2.22.2-1.71.2-0.9
Patch foraging time to switch 0 sec0.30.51.70.3-0.30.4-0.50.41.01.0-0.71.0-1.31.0-0.30.2
Patch foraging water rate 0 sec1.43.04.7-1.51.5-1.61.8-1.8-1.7-2.12.0-1.82.2-2.11.2-0.7
Patch foraging water rate 12 sec0.30.72.10.1-0.60.5-1.11.21.20.4-0.41.4-1.20.00.5-0.2
Patch foraging water rate 18 sec0.20.31.50.20.4-0.5-0.30.3-0.10.10.50.5-0.20.31.11.2
Patch foraging water rate 24 sec0.10.10.30.1-0.20.1-0.40.40.0-0.0-0.20.5-0.1-0.10.20.5
Patch foraging water rate 6 sec0.20.31.8-0.40.6-0.70.1-0.1-0.0-0.41.00.00.3-0.41.30.6
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.1-0.50.30.2-0.10.3-0.1-0.2-0.1-0.0-0.4-0.40.2
Distance traveled before self-admin0.30.40.8-0.5-0.20.1-0.70.70.50.3-0.40.9-0.90.20.9-0.9
Distance traveled after self-admin0.10.10.5-0.40.0-0.2-0.30.4-0.40.2-0.20.5-0.00.20.4-0.7
Extensor digitorum longus weight1.55.818.51.6-3.63.7-1.81.82.70.8-2.91.1-1.30.0-4.3-1.5
Bone: elastic displacement1.41.64.40.8-0.90.9-1.41.41.61.3-0.81.9-2.11.10.50.6
Bone: elastic work0.40.53.7-0.80.5-0.50.2-0.10.4-0.10.70.9-0.7-0.31.9-0.3
Bone: endosteal estimation14.331.338.3-6.16.2-6.16.0-6.0-6.1-5.45.4-5.85.8-4.94.1-4.4
Bone: endosteal perimeter16.635.345.4-6.76.1-6.16.0-6.0-6.6-6.25.6-5.95.7-6.04.3-5.6
Epididymis fat weight0.41.43.2-1.00.7-0.61.1-1.1-1.0-1.60.9-1.51.3-1.70.1-1.8
Delta time in closed arm before/after self-admin0.30.30.70.4-0.30.2-0.40.40.50.5-0.20.8-0.60.50.80.5
Delta time in open arm before/after self-admin0.70.75.11.0-0.70.7-0.00.0-0.1-0.1-0.4-0.80.80.0-2.30.6
Diff in mean of infusions in LGA sessions1.92.43.11.7-1.61.6-1.41.31.41.8-1.61.3-1.61.7-1.71.2
Delay discount exponential model param0.30.40.90.5-0.20.3-0.20.20.81.0-0.80.5-0.61.0-0.90.4
Extinction: sum of active levers before priming0.30.32.60.6-0.30.20.0-0.0-0.4-0.1-0.1-0.60.80.1-1.60.4
Active lever presses in extinction session 61.71.72.9-1.41.1-1.61.5-1.5-1.2-1.21.5-1.71.3-1.20.4-0.8
Bone: final force0.91.46.6-1.51.3-1.30.5-0.5-0.8-1.01.4-0.10.5-1.12.6-0.7
Bone: final moment0.91.57.6-1.61.4-1.40.5-0.5-0.7-1.01.40.00.5-1.02.8-0.7
Food consumed during 24 hour testing period2.73.76.0-1.61.3-1.32.0-2.0-2.0-2.21.5-2.42.4-2.30.0-2.3
Glucose1.01.63.30.6-1.81.5-1.41.51.20.8-1.51.3-1.80.5-1.0-0.7
Heart weight0.40.63.9-0.4-0.40.4-0.70.80.4-0.7-0.00.6-0.4-1.10.5-2.0
Delay discount hyperbolic model param0.30.40.90.5-0.30.4-0.20.20.80.9-0.80.5-0.60.9-0.90.3
Intermittent access intake day 1-15 change0.10.20.5-0.5-0.30.50.2-0.20.4-0.0-0.70.10.1-0.2-0.6-0.6
Intermittent access intake escalation0.20.41.5-1.10.20.00.7-0.6-0.2-0.6-0.2-0.40.5-0.8-0.4-1.2
Intermittent access intake escalation 20.40.51.5-1.10.3-0.20.9-0.8-0.3-0.60.0-0.50.7-0.8-0.1-1.2
Intermitt. access day 1 inactive lever presses1.03.85.9-1.92.3-2.32.4-2.4-1.8-1.62.2-2.22.3-1.41.3-0.6
Intermitt. access day 15 inactive lever presses1.12.34.4-1.71.5-1.42.1-2.1-0.6-1.31.6-1.81.9-1.21.0-0.0
Intermitt. access escalation Index1.72.43.91.2-1.61.6-2.02.01.41.4-1.71.7-2.01.3-1.20.1
Intermittent access day 1 total infusions0.61.01.8-0.81.0-1.01.0-1.0-1.2-1.20.8-1.31.3-1.10.6-0.2
Intermittent access day 15 total infusions1.62.34.9-1.70.9-0.71.6-1.5-1.3-2.00.8-1.92.0-2.20.2-1.7
Intermittent access terminal intake (last 3 days)2.63.56.1-2.01.4-1.22.1-2.0-1.8-2.41.1-2.32.5-2.40.6-1.5
Intermittent access total infusions2.42.85.0-1.51.3-1.11.8-1.7-1.9-2.11.1-2.22.2-2.10.6-1.0
Intermittent access day 1 locomotion4.05.05.8-2.32.3-2.32.4-2.3-2.0-2.32.2-2.42.4-2.32.2-1.4
Intermittent access day 15 total locomotion3.35.98.6-2.42.2-2.12.7-2.7-2.6-2.72.1-2.92.8-2.71.6-1.5
Intermittent access total locomotion6.67.910.8-2.72.8-2.63.2-3.2-2.9-3.02.6-3.33.2-2.92.2-1.4
Intermittent access standard deviation0.30.71.5-0.70.7-0.71.2-1.1-0.6-0.70.6-1.01.2-0.70.3-0.3
Left kidney weight0.10.41.80.1-0.50.1-0.80.80.30.10.11.1-1.00.01.40.3
Right kidney weight0.10.65.1-0.6-0.3-0.3-0.40.4-0.2-0.50.50.6-0.7-0.72.3-0.3
Cocaine induced anxiety0.30.41.4-0.0-0.20.1-0.70.70.70.6-0.11.0-0.90.51.2-0.5
Post-drug Anxiety0.50.61.40.0-0.50.3-0.90.90.90.6-0.31.2-1.10.41.1-0.7
Baseline Anxiety0.10.10.30.1-0.50.4-0.20.30.50.1-0.20.2-0.4-0.1-0.0-0.2
Tail length2.49.614.6-3.22.9-3.53.4-3.4-3.1-3.03.6-2.82.7-2.83.8-1.6
Length with tail2.08.513.1-3.02.4-2.92.8-2.8-3.4-3.33.1-2.42.2-3.23.6-2.4
Length without tail0.20.71.7-0.70.1-0.40.5-0.5-1.0-1.20.5-0.40.5-1.31.2-1.3
Times rat made contact with spout0.80.91.2-0.91.1-1.01.0-1.0-1.0-0.91.0-0.70.9-0.90.9-0.9
Lifetime Intake2.83.45.5-1.81.6-1.42.0-2.0-2.0-2.31.4-2.42.3-2.20.6-1.0
Liver weight, left3.65.910.7-2.42.8-3.32.5-2.5-3.2-2.02.7-1.81.5-1.73.0-1.0
Liver weight, right0.81.43.50.5-0.60.3-1.11.01.10.9-0.21.9-1.70.81.81.7
Locomotor activity0.30.51.7-0.50.6-0.30.9-0.9-0.9-0.50.1-1.31.3-0.30.2-0.0
Locomotor testing distance0.81.53.1-1.31.1-0.81.6-1.5-1.1-0.90.5-1.81.7-0.80.6-1.2
Locomotor testing rearing0.71.53.1-1.31.1-0.81.8-1.7-0.8-0.30.2-1.71.8-0.2-0.1-1.5
Locomotion in novel chamber0.20.31.2-0.30.20.0-0.30.40.20.1-0.40.8-1.0-0.11.10.5
Locomotion in novel chamber post-restriction1.22.03.7-1.41.3-1.30.8-0.8-1.9-1.81.5-1.51.4-1.71.1-1.2
Fecal boli incidents, locomotor time 10.10.20.7-0.4-0.30.20.1-0.1-0.3-0.5-0.1-0.20.5-0.6-0.1-0.9
Change in fecal boli incidents, locomotor task0.20.20.80.3-0.70.6-0.30.30.5-0.3-0.10.4-0.2-0.4-0.9-0.3
Time >=10cm from walls, locomotor time 12.62.73.71.3-1.71.6-1.91.91.71.7-1.91.9-1.81.5-1.60.4
Bouts of movement, locomotor time 10.20.20.60.8-0.40.4-0.40.40.70.5-0.10.4-0.50.4-0.40.7
Total resting periods, locomotor time 10.30.30.70.8-0.40.4-0.50.50.80.5-0.10.5-0.60.3-0.10.8
Rest time, locomotor task time 10.10.20.90.60.1-0.0-0.20.20.30.4-0.00.1-0.30.60.30.9
Distance moved, locomotor task time 10.20.31.0-0.70.4-0.40.6-0.6-0.2-0.70.6-0.40.4-0.8-0.0-1.0
Vertical activity count, locomotor time 10.10.30.6-0.70.6-0.50.5-0.5-0.2-0.70.6-0.10.4-0.8-0.0-0.3
Time >=10cm from walls, locomotor time 20.20.30.6-0.50.30.1-0.20.20.80.7-0.60.7-0.60.70.3-0.5
Bouts of movement, locomotor time 20.10.20.70.2-0.40.4-0.40.40.80.4-0.10.8-0.60.2-0.6-0.5
Total resting periods, locomotor time 20.20.41.20.4-0.60.5-0.60.61.00.6-0.31.1-0.80.5-0.7-0.5
Rest time, locomotor task time 22.22.84.91.9-1.91.4-2.22.21.51.5-1.31.7-1.81.4-1.50.9
Distance moved, locomotor task time 20.30.41.3-0.71.1-0.81.0-1.0-0.1-0.10.6-0.40.2-0.10.60.2
Vertical activity count, locomotor time 21.52.14.5-1.42.0-1.72.1-2.1-1.0-0.91.5-1.51.3-0.80.80.3
Light reinforcement 10.20.51.40.10.5-0.60.4-0.5-0.7-0.71.1-1.11.2-0.4-0.30.4
Light reinforcement 20.40.71.7-0.10.9-0.80.5-0.6-0.7-0.81.3-0.80.9-0.50.71.1
Bone: marrow area13.930.337.2-6.06.1-6.05.9-5.9-6.0-5.35.3-5.75.6-4.84.1-4.3
Bone: maximum diameter5.29.814.2-3.83.5-3.52.8-2.8-3.2-3.33.4-2.52.6-3.23.2-2.5
Bone: maximum force1.73.17.8-2.11.6-1.61.1-1.1-1.4-2.11.9-0.81.1-2.22.8-1.8
Bone: maximum moment1.83.28.9-2.21.8-1.71.1-1.1-1.3-2.02.0-0.71.1-2.13.0-1.7
Mean time between licks in bursts0.30.73.7-0.7-0.20.30.2-0.2-0.3-1.30.1-0.60.8-1.6-0.0-1.9
Mean num. licks in bursts0.20.30.5-0.20.4-0.40.7-0.7-0.4-0.60.7-0.60.4-0.7-0.1-0.4
Cd content in liver4.04.46.92.4-2.52.4-1.92.02.02.0-2.41.7-1.71.9-2.61.4
Co content in liver1.51.72.91.3-1.51.6-1.21.21.01.4-1.70.9-1.31.3-1.60.7
Cu content in liver0.40.40.8-0.60.9-0.90.8-0.8-0.6-0.50.9-0.60.4-0.30.60.2
Fe content in liver0.20.31.20.30.2-0.2-0.10.1-0.10.8-0.30.8-0.61.10.10.6
K content in liver0.20.21.30.10.6-0.50.2-0.3-1.1-0.30.3-0.40.50.20.20.5
Mg content in liver1.31.35.41.8-0.70.7-0.80.70.11.2-0.70.5-0.51.6-1.12.3
Mn content in liver1.11.28.31.50.1-0.0-0.70.6-0.20.9-0.00.5-0.31.50.42.9
Na content in liver0.40.41.6-0.10.9-0.90.5-0.6-1.3-0.10.6-0.60.20.40.00.7
Rb content in liver4.45.27.52.5-1.81.9-2.42.41.72.6-2.12.7-2.62.7-1.12.5
Se content in liver1.11.32.21.5-1.11.1-1.51.40.40.8-1.01.0-1.20.9-1.40.7
Sr content in liver1.21.02.0-1.41.0-1.00.8-0.8-0.8-1.01.1-0.60.5-1.11.2-1.2
Zn content in liver0.40.41.20.5-0.50.4-0.80.80.50.5-0.50.8-1.10.5-0.10.6
Bone: minimum diameter14.326.132.4-5.75.2-5.25.1-5.0-5.2-5.45.2-5.04.9-5.34.1-4.9
Time in familiar zone, hab. session 10.70.61.6-0.50.1-0.10.8-0.8-0.9-0.90.1-1.11.0-0.9-0.5-1.3
Time in novel zone, hab. session 10.80.81.90.6-0.40.3-1.01.01.41.1-0.31.2-1.31.00.11.0
Total zone transitions, hab. session 10.10.20.6-0.1-0.30.30.2-0.2-0.2-0.5-0.2-0.40.4-0.60.8-0.5
Total locomotion distance, hab. session 10.70.95.1-0.80.9-0.80.9-0.9-0.6-0.81.0-0.50.6-0.82.3-0.0
Locomotion velocity, hab. session 10.91.25.0-0.91.0-0.91.1-1.1-1.0-1.11.1-0.81.0-1.02.2-0.2
Time in familiar zone, hab. session 20.80.82.1-0.60.4-0.31.1-1.0-1.2-0.80.1-1.41.2-0.7-0.6-1.1
Time in novel zone, hab. session 20.80.81.70.4-0.30.2-1.11.01.20.70.11.3-1.20.61.11.3
Total zone transitions, hab. session 20.10.10.40.6-0.50.60.0-0.0-0.3-0.0-0.6-0.40.40.00.3-0.0
Total locomotion distance, hab. session 20.20.31.00.5-0.10.10.5-0.5-0.6-0.40.2-1.00.9-0.30.50.7
Locomotion velocity, hab. session 20.20.30.70.6-0.20.20.3-0.4-0.6-0.50.1-0.90.8-0.30.50.6
Novel to familiar place preference ratio0.50.61.1-0.90.8-0.90.5-0.5-0.5-0.91.1-0.20.3-1.00.5-1.0
Novelty place preference0.20.30.6-0.60.7-0.70.3-0.3-0.3-0.50.80.0-0.0-0.60.3-0.7
Time in novel zone, NPP test0.20.20.5-0.50.6-0.70.2-0.2-0.2-0.30.70.2-0.2-0.40.4-0.6
Total zone transitions, NPP test0.20.20.80.9-0.50.6-0.30.2-0.3-0.1-0.4-0.30.3-0.00.70.8
Total locomotion distance, NPP test0.40.52.40.00.4-0.40.6-0.6-0.7-0.50.6-0.90.8-0.31.50.9
Locomotion velocity, NPP test0.30.41.00.2-0.00.00.4-0.5-0.5-0.80.4-1.01.0-0.70.80.5
Intraocular pressure1.21.75.6-1.40.3-0.31.2-1.1-0.3-2.00.9-1.51.4-2.40.2-1.8
Delta distance traveled before/after self-admin0.10.10.40.5-0.1-0.1-0.20.2-0.20.6-0.00.30.10.7-0.60.4
Delta ambulatory time before/after self-admin0.10.10.40.30.1-0.10.2-0.1-0.50.10.2-0.00.60.2-0.10.4
Parametrial fat weight0.30.83.3-0.71.0-1.20.4-0.5-0.7-0.81.4-0.10.3-0.71.80.3
Pavlov. Cond. lever latency1.72.24.11.5-2.02.0-1.71.71.61.0-1.70.8-0.80.8-1.90.6
Pavlov. Cond. magazine entry latency3.64.68.3-2.02.8-2.92.4-2.4-2.4-1.62.7-1.81.4-1.32.3-0.5
Pavlov. Cond. change in total contacts2.93.15.8-1.72.4-2.42.1-2.2-1.8-1.12.2-1.41.2-0.81.7-0.4
Pavlov. Cond. index score3.03.86.9-1.92.6-2.62.2-2.2-2.2-1.52.4-1.41.2-1.22.0-0.7
Pavlov. Cond. latency score2.43.15.6-1.72.3-2.42.0-2.0-2.1-1.32.1-1.31.1-1.01.7-0.7
Pavlov. Cond. lever contacts2.22.75.1-1.72.3-2.21.9-2.0-1.7-1.01.9-0.90.9-0.82.0-0.7
Pavlov. Cond. magazine entry number2.53.26.21.5-2.52.5-2.02.12.01.2-2.31.5-1.30.8-1.80.0
Pavlov. Cond. intertrial magazine entries1.21.44.2-0.40.2-0.20.9-0.9-1.1-1.60.6-1.82.1-1.5-0.9-1.1
Pavlov. Cond. lever-magazine prob. diff.3.23.97.3-2.02.7-2.72.2-2.2-2.2-1.52.5-1.41.1-1.32.1-0.7
Pavlov. Cond. response bias4.65.611.1-2.23.3-3.32.5-2.6-2.5-1.63.1-1.51.5-1.13.1-0.1
Pavlov. Cond. lever latency0.30.40.90.7-0.90.9-0.70.71.00.5-0.70.7-0.70.3-0.30.3
Pavlov. Cond. magazine entry latency2.22.74.21.3-1.71.8-1.91.91.41.6-2.02.0-1.71.5-1.40.3
Pavlov. Cond. change in total contacts0.30.41.6-0.20.7-0.60.7-0.7-1.2-0.30.3-1.00.90.0-0.5-0.2
Pavlov. Cond. index score0.00.00.1-0.10.2-0.1-0.10.1-0.30.2-0.30.2-0.10.3-0.3-0.3
Pavlov. Cond. latency score0.10.10.2-0.10.1-0.0-0.30.3-0.10.3-0.40.5-0.30.4-0.2-0.3
Pavlov. Cond. lever contacts0.20.30.6-0.50.7-0.70.6-0.6-0.8-0.40.5-0.60.6-0.20.0-0.1
Pavlov. Cond. magazine entry number3.13.85.4-1.71.9-2.02.3-2.3-1.8-2.12.3-2.22.0-2.01.3-0.9
Pavlov. Cond. intertrial magazine entries12.118.122.0-4.44.2-4.24.7-4.7-4.2-4.64.7-4.74.0-4.43.1-3.2
Pavlov. Cond. lever-magazine prob. diff.0.00.10.1-0.00.00.0-0.30.3-0.20.3-0.40.3-0.20.4-0.3-0.2
Pavlov. Cond. response bias0.00.00.2-0.00.2-0.1-0.00.0-0.40.0-0.1-0.10.20.2-0.30.0
Time in closed arm before self-admin0.10.10.5-0.20.4-0.70.0-0.00.20.50.30.1-0.60.40.2-0.0
Time in closed arm after self-admin0.60.62.00.6-0.40.2-0.90.90.71.1-0.51.2-1.40.9-0.00.2
Time in open arm before self-admin0.91.02.3-0.1-0.81.0-1.21.21.10.7-1.01.5-1.40.31.0-0.4
Time in open arm after self-admin0.30.30.8-0.2-0.30.50.3-0.3-0.3-0.8-0.2-0.80.8-0.9-0.7-0.6
Bone: periosteal estimation9.820.826.9-5.25.2-5.24.6-4.5-4.6-4.54.9-4.14.3-4.24.4-3.4
Bone: periosteal perimeter6.110.517.6-4.23.6-3.62.8-2.8-3.3-3.33.4-2.22.3-3.33.4-3.4
Bone: post-yield work1.92.75.4-2.21.6-1.61.5-1.4-1.5-1.81.4-1.21.4-1.91.3-2.3
Progressive ratio test 1 active lever presses2.83.55.6-1.91.8-1.72.0-1.9-1.9-2.21.8-2.22.4-2.11.0-1.0
Progressive ratio test 1 breakpoint3.23.96.2-1.91.9-1.92.1-2.1-2.0-2.32.0-2.32.5-2.21.0-0.9
Progressive ratio test 1 inactive lever presses2.94.26.4-2.12.1-1.92.3-2.2-2.1-2.31.9-2.52.5-2.11.0-1.0
Progressive ratio test 2 active lever presses6.07.010.3-2.92.5-2.32.7-2.6-2.7-3.22.5-2.83.2-3.11.6-1.8
Progressive ratio test 2 breakpoint6.67.611.0-3.02.6-2.42.8-2.7-2.8-3.32.6-2.93.3-3.31.6-2.1
Progressive ratio test 2 inactive lever presses2.54.06.4-1.91.7-1.62.1-2.1-1.8-2.51.9-2.52.5-2.41.2-1.0
Incentive Sensitization - Responses3.24.56.9-2.52.0-1.82.0-2.0-2.3-2.61.9-1.92.2-2.61.4-2.1
Incentive Sensitization - Breakpoint3.44.56.7-2.52.0-1.82.0-2.0-2.2-2.61.8-1.92.2-2.61.3-2.1
Sum of active levers in priming session hrs 5-61.00.95.00.9-1.01.0-0.60.60.60.7-1.10.3-0.20.8-2.20.9
Progressive ratio0.20.31.5-0.20.1-0.7-0.10.1-1.0-0.60.6-0.30.1-0.6-0.5-1.2
Food seeking constrained by brief footshock2.53.16.0-1.71.5-1.72.1-2.1-2.2-1.51.2-2.41.8-1.30.7-1.5
Seeking ratio, punishment vs. effort0.91.22.7-1.21.2-0.71.6-1.6-0.7-0.80.6-1.51.3-0.71.2-0.2
Retroperitoneal fat weight0.52.02.6-1.21.3-1.31.5-1.5-1.2-1.51.6-1.61.4-1.51.6-1.0
Reaction time number correct0.20.41.30.4-0.80.7-1.11.10.5-0.0-0.40.7-0.6-0.2-0.1-0.2
Reaction time mean minus median0.10.30.90.3-0.60.6-0.40.40.90.6-0.50.2-0.50.5-0.00.8
Reaction time mean minus median AUC0.61.62.01.3-1.41.3-1.41.41.41.3-1.20.9-1.41.2-0.31.3
Reaction time num false alarms3.34.76.7-2.42.3-2.32.1-2.1-2.6-2.32.1-2.01.9-2.12.0-1.7
Reaction time num false alarms AUC3.25.17.7-2.42.5-2.52.2-2.2-2.8-2.32.4-2.12.0-2.12.3-1.1
Reaction time trials correct on left0.20.41.30.4-0.80.7-1.11.10.5-0.0-0.40.7-0.6-0.2-0.1-0.2
Reaction time trials on left0.20.41.20.3-0.70.6-1.11.10.5-0.1-0.30.7-0.6-0.30.0-0.1
Reaction time mean1.01.53.21.2-0.80.9-1.11.11.41.6-1.11.0-1.31.8-0.31.8
Reaction time mean AUC1.42.24.51.5-1.01.1-1.21.21.72.0-1.41.1-1.52.1-0.72.0
Median of all reaction times1.21.63.81.3-0.80.8-1.11.11.41.7-1.11.1-1.31.9-0.41.7
Reaction time omissions0.30.41.6-0.50.5-0.70.4-0.40.2-0.30.9-0.40.1-0.31.20.9
Reaction time false alarm rate3.24.46.2-2.22.5-2.52.4-2.4-2.5-1.92.1-1.91.8-1.61.8-1.0
Reaction time premature initiation rate1.11.52.3-1.21.1-1.21.2-1.2-0.9-1.31.5-1.41.5-1.31.0-1.3
Reaction time premature initiations0.61.01.8-1.00.6-0.70.6-0.6-0.8-1.31.2-1.11.2-1.31.0-1.3
Std. dev. reaction times0.40.82.50.8-0.70.6-0.60.61.11.1-0.70.6-0.91.1-0.01.6
Reaction time trials completed0.20.41.20.3-0.70.6-1.11.10.5-0.1-0.30.7-0.6-0.30.0-0.1
Reaction time trials AUC0.20.41.30.4-0.80.7-1.11.10.5-0.0-0.40.7-0.6-0.2-0.0-0.1
Run reversals in cocaine runway, females0.30.31.7-0.6-0.50.6-0.10.11.3-0.1-0.30.3-0.6-0.60.6-0.6
Run reversals in cocaine runway, males0.20.21.3-0.6-0.20.0-0.20.30.4-0.20.00.5-0.4-0.41.1-0.6
Latency to leave start box in cocaine runway0.20.20.7-0.0-0.40.4-0.40.40.90.4-0.50.6-0.50.30.40.2
Latency to leave start box in cocaine runway, F0.40.51.2-0.4-0.20.3-0.70.71.00.4-0.51.1-1.10.20.9-0.8
Latency to leave start box in cocaine runway, M0.30.32.40.4-0.10.10.2-0.30.10.3-0.2-0.40.60.6-0.31.6
Std. dev. time between licks in bursts0.10.10.70.3-0.40.50.0-0.00.3-0.1-0.3-0.10.3-0.2-0.8-0.3
Total sessions with >9 infusions0.30.41.1-0.70.1-0.00.5-0.5-0.2-0.90.1-0.70.8-1.0-0.6-0.8
Short access day 1 total inactive lever presses2.33.05.1-2.31.8-1.71.8-1.8-1.4-1.81.8-1.81.2-1.91.8-1.3
Short access day 10 total inactive lever presses0.10.20.7-0.40.2-0.10.6-0.60.2-0.60.5-0.70.9-0.60.1-0.2
Short access day 1 total infusions0.40.51.2-0.70.5-0.40.7-0.7-0.5-0.90.5-1.10.8-0.9-0.70.0
Short access day 10 total infusions2.53.25.5-1.91.6-1.42.1-2.1-1.7-2.11.4-2.32.1-2.00.4-1.0
Short access total infusions1.31.73.0-1.41.3-1.21.5-1.5-1.2-1.51.1-1.71.5-1.40.2-0.5
Short access day 1 locomotion2.12.66.1-1.81.2-1.01.7-1.7-1.0-2.21.4-1.82.0-2.50.6-1.0
Short access day 10 total locomotion3.87.010.3-2.62.8-2.73.2-3.2-2.5-2.52.7-3.12.9-2.41.9-1.3
Short access total locomotion3.13.75.2-2.21.8-1.72.3-2.2-1.4-2.11.8-2.12.1-2.31.1-1.4
One hour access (0.3 mA shock)1.31.42.4-1.61.1-0.91.2-1.2-1.2-1.50.8-1.21.3-1.40.5-1.3
Compulsive drug intake0.50.62.10.1-0.50.3-1.21.20.50.7-0.41.3-1.50.60.3-0.6
One hour access (shock baseline)1.01.63.8-1.01.0-0.71.6-1.6-1.2-1.50.7-1.62.0-1.40.2-0.0
Social response proportion0.20.30.5-0.2-0.70.7-0.40.40.5-0.3-0.60.7-0.5-0.7-0.3-0.6
Social responses0.10.10.2-0.3-0.00.10.3-0.3-0.3-0.4-0.2-0.20.4-0.5-0.1-0.1
Social time0.30.41.4-1.20.2-0.20.4-0.40.1-0.70.1-0.20.2-1.1-0.2-1.0
Soleus weight0.30.92.7-1.60.8-0.70.6-0.6-0.7-1.00.7-0.20.0-1.20.8-1.6
Bone: stiffness0.40.61.4-0.60.6-0.50.3-0.3-1.2-1.10.5-0.50.8-1.01.1-0.8
Tibialis anterior weight0.31.04.6-0.8-0.40.50.8-0.8-0.2-1.0-0.0-0.60.7-1.4-1.4-2.1
Time to tail flick, vehicle, before self-admin0.30.41.8-0.30.20.2-0.60.60.30.0-0.50.7-0.80.01.30.8
Time to tail flick, vehicle, after self-admin0.10.10.4-0.30.2-0.2-0.20.2-0.6-0.60.4-0.30.0-0.60.4-0.5
Time to tail flick, test, before self-admin0.20.20.60.2-0.10.1-0.10.10.40.8-0.60.4-0.70.7-0.2-0.1
Time to tail flick, test, after self-admin0.00.00.10.10.3-0.3-0.0-0.0-0.10.10.2-0.3-0.30.30.3-0.1
Delta time to tail flick, vehicle, before/after SA1.21.22.6-0.60.8-1.21.1-1.2-1.3-1.01.5-1.61.1-0.8-0.3-0.9
Delta time to tail flick, test, before/after SA0.10.10.10.30.1-0.0-0.30.3-0.4-0.10.1-0.20.00.10.20.4
Tibia length0.20.64.8-0.50.1-0.2-0.50.5-0.3-0.30.30.9-0.7-0.42.2-0.3
Ambulatory time before self-admin0.20.31.3-0.70.1-0.4-0.50.50.10.10.00.7-0.60.10.9-1.1
Ambulatory time after self-admin0.20.20.9-0.60.3-0.6-0.00.1-0.40.10.40.40.10.10.9-0.7
Bone: tissue strength1.41.42.31.3-1.41.4-1.51.51.00.9-1.31.4-1.20.8-0.20.4
Total heroin consumption0.40.41.2-0.51.1-1.10.6-0.6-1.0-0.10.5-0.50.30.30.50.1
Bone: trabecular number2.03.38.5-1.32.5-2.51.4-1.5-1.8-1.32.6-1.31.1-0.92.90.9
Bone: trabecular spacing1.01.36.20.7-1.51.5-0.60.60.60.6-1.70.2-0.10.4-2.5-1.1
Bone: trabecular thickness3.64.512.7-2.32.6-2.71.7-1.7-1.4-1.93.1-1.01.3-1.93.6-0.3
Bone: trabecular tissue density0.91.32.81.4-1.11.1-1.71.71.10.4-0.51.6-1.30.20.51.1
Water consumed over 24 hours0.10.10.7-0.20.5-0.40.3-0.3-0.2-0.20.50.10.2-0.30.8-0.2
Number of responses in last shaping day0.30.41.4-1.20.6-0.30.6-0.50.0-0.60.4-0.50.1-0.70.9-0.5