Cyb5d2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative polyA NM_001007671.1 0.07 0.05 2.4e-03 0.02 0.01 0.02 0.01 4.4e-02 4.9e-02 3.4e-02 6.8e-02
2 BLA isoform ratio NM_001007671.1 0.11 0.08 7.3e-05 0.05 0.07 0.06 0.06 9.0e-04 1.8e-04 6.3e-04 3.4e-04
3 BLA isoform ratio XM_006246730.4 0.11 0.08 5.7e-05 0.05 0.07 0.06 0.06 1.6e-03 1.1e-04 3.2e-04 2.3e-04
4 BLA alternative TSS XM_006246730.4 0.06 0.05 4.5e-03 0.03 0.04 0.04 0.03 7.9e-03 5.8e-03 4.3e-03 6.5e-03
5 BLA alternative TSS NM_001007671.1 0.06 0.05 5.5e-03 0.03 0.03 0.04 0.03 9.9e-03 7.8e-03 5.4e-03 8.2e-03
6 BLA alternative polyA XM_006246730.4 0.07 0.05 2.1e-03 0.02 0.02 0.02 0.01 3.9e-02 4.4e-02 4.3e-02 6.0e-02
7 BLA gene expression Cyb5d2 0.08 0.06 1.1e-03 0.03 0.04 0.04 0.04 6.7e-03 5.3e-03 4.8e-03 5.0e-03
8 Liver alternative polyA XM_006246730.4 0.05 0.04 5.4e-05 0.04 0.04 0.03 0.03 8.0e-05 9.0e-05 1.0e-04 1.2e-04
9 Brain intron excision ratio chr10_57400881_57407389 0.04 0.03 5.0e-04 0.04 0.04 0.03 0.04 6.2e-05 2.6e-04 7.8e-04 1.7e-04
10 Adipose isoform ratio XM_006246730.4 0.05 0.04 3.1e-05 0.03 0.02 0.03 0.02 5.3e-04 2.6e-03 6.7e-04 2.2e-03
11 Liver alternative polyA NM_001007671.1 0.05 0.04 4.9e-05 0.04 0.04 0.03 0.03 7.9e-05 8.4e-05 1.0e-04 1.1e-04
12 BLA intron excision ratio chr10_57407529_57412543 0.08 0.06 2.4e-03 0.06 0.04 0.03 0.04 5.3e-04 3.6e-03 7.4e-03 2.1e-03
13 Adipose isoform ratio NM_001007671.1 0.06 0.04 1.9e-05 0.03 0.02 0.03 0.02 3.7e-04 1.7e-03 8.5e-04 1.4e-03
14 Adipose gene expression Cyb5d2 0.07 0.05 1.3e-06 0.04 0.04 0.04 0.04 9.5e-06 4.5e-05 2.6e-05 6.2e-05
15 pVTA gene expression Cyb5d2 0.11 0.08 2.3e-04 0.11 0.05 0.09 0.03 2.2e-05 2.9e-03 1.6e-04 2.4e-02
16 Liver gene expression Cyb5d2 0.21 0.12 0.0e+00 0.15 0.15 0.15 0.15 1.8e-16 1.5e-16 4.3e-16 1.6e-16
17 Liver isoform ratio NM_001007671.1 0.03 0.02 3.3e-03 0.01 0.02 0.02 0.01 1.3e-02 5.5e-03 5.9e-03 1.2e-02
18 Liver isoform ratio XM_006246730.4 0.03 0.02 3.9e-03 0.01 0.02 0.02 0.01 1.3e-02 5.2e-03 4.9e-03 1.0e-02
19 pVTA isoform ratio NM_001007671.1 0.07 0.05 8.3e-03 0.03 0.03 0.06 0.01 2.8e-02 3.0e-02 2.2e-03 1.3e-01
20 Adipose mRNA stability Cyb5d2 0.09 0.06 5.7e-09 0.04 0.06 0.06 0.06 1.2e-05 1.3e-07 5.2e-07 5.0e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.40.72.2-0.10.1-0.10.5-0.50.80.6-0.70.6-0.80.80.70.70.70.7-1.0-1.2-1.41.51.4
Area under the delay curve0.00.00.20.2-0.20.2-0.20.3-0.4-0.10.00.00.0-0.0-0.1-0.1-0.1-0.10.10.30.3-0.4-0.3
BMI with tail0.20.81.10.8-0.80.8-0.60.6-0.50.9-1.00.9-0.80.80.90.91.01.0-1.0-1.0-1.01.01.0
BMI without tail0.51.11.80.9-0.80.9-0.70.6-0.41.1-1.31.1-1.11.11.01.31.01.0-1.3-1.3-1.31.21.3
Body weight0.62.67.00.4-0.30.30.3-0.30.71.4-1.61.4-1.61.61.51.71.51.5-1.9-2.3-2.62.62.6
Weight adjusted by age3.03.44.21.9-2.02.0-1.61.6-1.61.9-2.02.0-2.12.11.91.81.91.9-1.9-1.8-1.71.51.6
Bone surface1.11.92.51.1-1.11.1-0.90.8-0.61.5-1.41.3-1.51.51.51.51.51.5-1.5-1.6-1.51.61.5
Bone volume1.52.53.21.3-1.31.4-1.11.0-0.81.8-1.61.5-1.81.81.81.71.81.8-1.8-1.8-1.71.71.7
Breakpoint value in progressive ratio session0.80.92.30.4-0.40.50.2-0.2-0.00.6-1.11.2-1.21.20.60.70.50.5-1.2-1.3-1.51.31.4
Number of licking bursts0.30.30.4-0.50.5-0.50.4-0.40.3-0.60.6-0.60.6-0.6-0.6-0.6-0.6-0.60.60.60.6-0.6-0.6
Context. condit. distance diff. score1.31.52.31.0-0.90.9-0.70.6-0.51.3-1.31.2-1.41.41.41.31.41.4-1.4-1.5-1.51.51.5
Locomotion velocity, session 12.42.64.91.0-0.90.9-0.40.3-0.21.5-1.81.7-1.81.81.61.71.61.6-1.9-2.1-2.22.22.2
Locomotion distance, session 11.01.31.81.2-1.21.2-1.01.0-1.11.1-1.31.3-1.31.31.11.21.11.1-1.2-1.2-1.11.01.1
Locomotion velocity, session 20.20.20.9-0.70.7-0.70.9-0.91.0-0.30.3-0.20.3-0.3-0.3-0.1-0.3-0.30.1-0.1-0.20.40.2
Locomotion distance, session 20.20.30.80.2-0.20.20.1-0.10.20.5-0.60.6-0.60.60.50.60.50.5-0.7-0.8-0.90.90.9
Locomotion velocity, session 32.32.73.4-1.51.5-1.51.2-1.10.9-1.71.8-1.81.8-1.8-1.7-1.7-1.7-1.71.81.81.8-1.7-1.8
Locomotion distance, session 30.20.20.3-0.50.5-0.50.4-0.40.4-0.40.5-0.50.5-0.5-0.4-0.4-0.4-0.40.40.40.4-0.3-0.4
Stereotopy head waving bouts, day 30.00.00.1-0.20.2-0.20.2-0.20.3-0.00.1-0.20.2-0.2-0.0-0.0-0.0-0.00.10.0-0.00.10.0
Stereotopy head waving duration, day 30.20.31.10.6-0.60.6-0.90.9-1.00.10.0-0.20.1-0.1-0.00.1-0.0-0.00.20.50.7-0.8-0.7
Locomotion velocity, session 70.10.10.20.3-0.30.3-0.30.3-0.40.3-0.20.3-0.20.20.20.20.20.2-0.2-0.1-0.10.10.1
Locomotion distance, session 70.00.00.0-0.10.2-0.20.2-0.20.2-0.10.1-0.10.1-0.1-0.0-0.1-0.0-0.00.10.0-0.00.00.0
Stereotopy head waving bouts, day 71.11.31.61.0-1.01.0-0.90.9-0.71.3-1.31.1-1.11.11.31.31.31.3-1.3-1.2-1.21.21.2
Stereotopy head waving duration, day 71.41.72.11.1-1.11.1-0.90.9-0.71.4-1.41.3-1.31.31.41.41.41.4-1.5-1.4-1.41.41.4
Locomotion velocity, session 81.11.41.61.1-1.11.1-1.01.0-0.91.3-1.31.2-1.31.31.31.31.31.3-1.2-1.2-1.11.11.1
Locomotion distance, session 81.72.54.81.0-0.90.9-0.50.4-0.31.6-1.71.7-1.81.81.71.71.71.7-1.8-2.0-2.12.22.1
Degree of sensitization distance0.80.81.10.9-0.80.8-0.70.7-0.60.9-1.01.1-1.01.00.90.90.90.9-0.9-0.9-0.90.80.9
Degree of sensitization stereotypy1.31.42.60.8-0.80.8-0.50.4-0.31.3-1.31.2-1.21.21.31.31.31.3-1.4-1.5-1.61.61.6
Conditioned locomotion0.91.11.8-0.70.7-0.70.4-0.40.2-1.01.1-1.21.1-1.1-1.1-1.1-1.1-1.11.21.31.3-1.3-1.3
Cocaine response after cond. corrected0.40.51.2-0.91.0-1.01.1-1.11.1-0.60.6-0.40.5-0.5-0.6-0.5-0.6-0.60.40.1-0.00.20.0
Cocaine response after cond. not corrected0.20.20.6-0.50.6-0.60.8-0.80.8-0.30.2-0.10.1-0.1-0.3-0.2-0.3-0.30.0-0.2-0.30.50.3
Cocaine response before conditioning0.81.01.31.0-1.01.0-0.90.9-0.71.1-1.11.1-1.11.11.01.11.01.0-1.1-1.0-1.00.91.0
Saline control response0.50.70.90.8-0.80.8-0.60.6-0.60.8-0.90.9-0.90.90.80.80.80.8-0.9-0.9-0.90.80.8
Bone: connectivity density0.81.33.20.5-0.40.4-0.0-0.00.31.1-1.11.1-1.21.21.21.21.21.2-1.4-1.6-1.71.81.7
Bone: cortical apparent density1.21.62.1-1.11.1-1.10.9-0.80.5-1.41.4-1.21.4-1.4-1.4-1.4-1.4-1.41.41.41.4-1.4-1.4
Bone: cortical area0.20.20.90.0-0.10.1-0.30.3-0.4-0.40.5-0.50.4-0.4-0.4-0.4-0.4-0.40.50.70.7-1.0-0.8
Bone: cortical porosity1.41.53.6-1.71.7-1.61.8-1.81.9-1.11.1-1.31.1-1.1-1.0-1.0-1.0-1.00.80.50.3-0.1-0.2
Bone: cortical porosity1.41.53.2-1.71.6-1.61.7-1.71.8-1.11.2-1.51.2-1.2-1.1-1.1-1.1-1.10.90.70.5-0.3-0.4
Bone: cortical thickness2.44.05.0-1.91.9-1.91.6-1.51.4-2.12.2-2.22.2-2.2-2.1-2.1-2.1-2.12.22.12.0-2.0-2.0
Bone: cortical thickness4.04.66.5-2.52.5-2.52.5-2.52.5-2.22.2-2.22.2-2.2-2.2-2.1-2.2-2.22.01.61.4-1.3-1.3
Bone: cortical tissue density1.01.31.7-1.01.0-1.00.8-0.80.5-1.31.3-1.11.3-1.3-1.3-1.2-1.3-1.31.31.31.3-1.3-1.2
Condit. Reinf. active minus inactive responses0.91.02.1-1.31.3-1.31.4-1.51.3-1.00.9-0.90.9-0.9-0.9-0.9-0.9-0.90.70.50.4-0.2-0.3
Condit. Reinf. active-inactive response ratio0.60.61.3-1.11.0-1.01.1-1.11.0-0.80.7-0.80.7-0.7-0.8-0.7-0.8-0.80.60.40.3-0.2-0.3
Condit. Reinf. active responses0.60.71.7-1.11.2-1.11.3-1.31.2-0.80.7-0.70.7-0.7-0.8-0.7-0.8-0.80.60.30.2-0.1-0.2
Condit. Reinf. inactive responses0.00.00.1-0.10.2-0.20.2-0.20.1-0.20.2-0.00.2-0.2-0.2-0.2-0.2-0.20.20.20.2-0.2-0.2
Incentive salience index mean1.11.33.3-1.61.6-1.61.8-1.81.7-1.11.0-0.90.9-0.9-1.0-0.9-1.0-1.00.70.40.2-0.0-0.1
Condit. Reinf. lever presses1.11.55.0-1.71.8-1.72.2-2.22.2-0.90.7-0.70.7-0.7-0.8-0.8-0.8-0.80.4-0.1-0.40.60.4
Condit. Reinf. active minus inactive responses0.40.61.7-1.01.1-1.11.1-1.11.3-0.60.7-0.60.7-0.7-0.6-0.6-0.6-0.60.50.30.10.0-0.1
Condit. Reinf. active-inactive response ratio0.80.81.6-1.11.2-1.21.2-1.21.3-0.90.9-0.80.9-0.9-0.9-0.8-0.9-0.90.70.50.4-0.3-0.4
Condit. Reinf. active responses0.20.20.8-0.60.7-0.70.7-0.70.9-0.40.5-0.30.4-0.4-0.3-0.3-0.3-0.30.30.10.00.1-0.0
Condit. Reinf. inactive responses0.10.10.30.4-0.40.4-0.50.5-0.50.4-0.20.3-0.20.20.40.30.40.4-0.1-0.10.00.0-0.0
Condit. Reinf. lever presses0.30.50.9-0.30.4-0.40.1-0.10.1-0.60.8-0.60.8-0.8-0.7-0.6-0.7-0.70.80.91.0-1.0-1.0
Condit. Reinf. lever reinforcers received0.10.20.6-0.50.6-0.60.6-0.60.7-0.40.5-0.30.4-0.4-0.3-0.3-0.3-0.30.30.20.1-0.0-0.1
Conditioned reinforcement - actives1.11.11.81.1-1.01.0-1.01.0-0.81.2-1.01.1-1.01.01.31.11.21.2-1.0-0.9-0.80.90.8
Conditioned reinforcement - inactives1.71.92.81.7-1.61.6-1.61.6-1.31.4-1.31.4-1.41.41.41.41.31.3-1.4-1.2-1.00.91.1
Conditioned locomotion0.40.51.71.1-0.90.9-1.31.3-0.90.7-0.40.5-0.40.40.70.60.60.6-0.3-0.00.0-0.2-0.1
Patch foraging indifference point 0 sec1.62.54.5-1.91.8-1.82.1-2.11.8-1.81.4-1.41.6-1.6-1.7-1.7-1.7-1.71.20.90.7-0.7-0.7
Patch foraging indifference point AUC1.41.65.41.8-1.81.8-1.81.8-2.31.0-1.11.4-1.21.20.90.90.70.7-0.8-0.4-0.2-0.10.1
Delay disc. indifference point, 0s delay2.22.43.11.7-1.81.8-1.61.5-1.61.6-1.71.6-1.71.71.51.61.51.5-1.5-1.3-1.11.11.2
Delay disc. indifference point, 16s delay0.30.41.10.8-0.90.9-0.90.9-1.00.5-0.50.5-0.50.50.40.40.40.4-0.3-0.10.1-0.2-0.0
Delay disc. indifference point, 2s delay0.20.20.4-0.30.3-0.30.2-0.20.0-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.50.50.60.6-0.6-0.6
Delay disc. indifference point, 24s delay0.90.91.1-0.91.0-1.01.0-0.90.6-1.01.0-0.91.0-1.0-1.0-1.0-1.0-1.00.90.80.8-0.7-0.8
Delay disc. indifference point, 4s delay0.40.50.70.8-0.80.8-0.80.8-0.80.7-0.70.7-0.70.70.70.60.70.7-0.6-0.5-0.50.40.4
Delay disc. indifference point, 8s delay0.00.00.00.1-0.10.1-0.10.1-0.20.0-0.00.1-0.00.00.0-0.00.00.00.00.00.0-0.1-0.1
Indifference point function ln k5.47.513.7-3.53.5-3.53.4-3.43.7-2.72.8-2.92.8-2.8-2.5-2.6-2.5-2.52.31.71.4-1.1-1.3
Indifference point function log k5.47.513.7-3.53.5-3.53.4-3.43.7-2.72.8-2.92.8-2.8-2.5-2.6-2.5-2.52.31.71.4-1.1-1.3
Patch foraging total patch changes 0 sec1.11.73.1-1.61.5-1.51.8-1.81.5-1.51.2-1.11.3-1.3-1.4-1.4-1.4-1.41.00.70.6-0.6-0.5
Patch foraging total patch changes 12 sec0.91.12.01.3-1.41.4-1.21.2-1.41.0-1.21.3-1.11.10.90.90.80.8-1.0-0.8-0.80.40.7
Patch foraging total patch changes 18 sec0.40.51.10.8-1.01.0-0.60.6-1.10.5-0.90.9-0.80.80.50.60.40.4-0.8-0.6-0.60.20.5
Patch foraging total patch changes 24 sec0.20.31.20.8-0.90.8-0.70.7-1.10.2-0.50.6-0.40.40.10.20.00.0-0.3-0.1-0.1-0.4-0.1
Patch foraging total patch changes 6 sec0.71.12.81.4-1.71.7-1.31.4-1.70.7-1.21.1-1.01.00.60.70.60.6-0.9-0.5-0.5-0.10.3
Patch foraging time to switch 0 sec1.62.43.01.6-1.61.7-1.51.5-1.11.7-1.71.4-1.71.71.71.71.71.7-1.6-1.5-1.41.31.3
Patch foraging water rate 0 sec0.91.41.9-1.11.1-1.10.9-0.90.7-1.11.4-1.31.4-1.4-1.1-1.2-1.1-1.11.31.31.3-1.2-1.2
Patch foraging water rate 12 sec0.30.41.00.4-0.40.4-0.30.3-0.20.9-0.50.6-0.50.51.00.80.90.9-0.7-0.8-0.70.90.8
Patch foraging water rate 18 sec0.30.41.5-0.91.0-1.01.1-1.11.2-0.20.4-0.40.4-0.4-0.1-0.2-0.1-0.10.1-0.2-0.30.60.4
Patch foraging water rate 24 sec0.10.10.30.3-0.10.1-0.50.5-0.20.50.2-0.20.1-0.10.60.40.50.50.10.10.20.0-0.1
Patch foraging water rate 6 sec0.30.51.0-0.60.7-0.70.3-0.30.4-0.41.0-0.91.0-1.0-0.3-0.5-0.3-0.30.90.80.9-0.6-0.8
Seeking ratio, delayed vs. immediate footshock0.60.71.3-0.80.6-0.60.6-0.60.4-1.00.8-0.90.8-0.8-1.0-0.9-1.0-1.00.91.01.0-1.1-1.0
Distance traveled before self-admin0.30.31.20.8-0.80.8-1.01.0-1.10.2-0.30.3-0.30.30.10.30.10.1-0.00.20.3-0.6-0.4
Distance traveled after self-admin6.37.09.73.1-3.13.1-3.13.1-2.92.7-2.72.6-2.72.72.62.82.62.6-2.4-2.0-1.81.51.7
Extensor digitorum longus weight3.915.417.84.1-4.14.1-3.83.7-3.34.2-4.24.1-4.24.24.24.24.24.2-4.0-3.7-3.43.33.4
Bone: elastic displacement0.30.30.9-0.20.2-0.2-0.00.1-0.1-0.60.7-0.60.6-0.6-0.6-0.6-0.6-0.60.70.80.8-1.0-0.9
Bone: elastic work1.41.82.8-1.01.0-1.00.7-0.70.6-1.41.5-1.41.4-1.4-1.5-1.4-1.5-1.51.51.51.5-1.7-1.5
Bone: endosteal estimation2.86.09.63.0-3.13.1-3.13.1-3.12.5-2.52.4-2.52.52.32.42.32.3-2.1-1.7-1.41.11.3
Bone: endosteal perimeter3.06.39.53.0-3.13.1-3.13.0-3.12.5-2.62.4-2.52.52.42.52.42.4-2.3-1.8-1.51.31.5
Epididymis fat weight4.29.812.72.9-2.72.8-2.22.1-1.83.2-3.53.5-3.43.43.13.33.13.1-3.6-3.5-3.63.33.5
Delta time in closed arm before/after self-admin0.90.92.11.0-1.31.3-0.90.9-1.40.8-1.11.0-1.11.10.70.80.70.7-0.9-0.7-0.50.40.6
Delta time in open arm before/after self-admin0.90.91.21.0-0.90.9-0.90.8-0.51.0-0.91.0-0.90.91.11.11.01.0-1.0-0.9-1.00.90.9
Diff in mean of infusions in LGA sessions0.20.30.9-0.50.6-0.60.8-0.81.0-0.1-0.1-0.1-0.20.20.00.1-0.1-0.1-0.3-0.6-0.80.80.8
Delay discount exponential model param0.10.10.20.1-0.10.1-0.00.00.20.3-0.20.2-0.20.20.30.30.30.3-0.3-0.3-0.30.40.3
Extinction: sum of active levers before priming1.41.43.00.6-0.70.7-0.20.1-0.21.0-1.41.2-1.31.31.11.21.01.0-1.5-1.7-1.71.71.7
Active lever presses in extinction session 61.51.52.51.1-1.11.1-0.60.6-0.61.1-1.51.5-1.41.41.11.21.01.0-1.5-1.5-1.61.31.5
Bone: final force0.60.91.21.1-1.11.1-1.01.0-1.01.0-1.00.9-1.11.11.01.01.01.0-1.0-0.8-0.80.60.7
Bone: final moment0.61.01.41.1-1.21.2-1.21.2-1.11.0-0.90.9-1.11.11.01.01.01.0-0.9-0.8-0.70.50.6
Food consumed during 24 hour testing period0.50.61.3-1.11.0-1.01.1-1.11.2-0.70.7-0.80.7-0.7-0.6-0.7-0.6-0.60.50.30.2-0.2-0.1
Glucose0.71.13.60.1-0.20.1-0.60.7-1.0-0.80.8-0.70.9-0.9-0.9-1.0-0.9-0.91.21.51.7-1.9-1.7
Heart weight1.21.62.31.3-1.31.3-1.11.0-0.91.3-1.51.4-1.51.51.21.31.21.2-1.4-1.3-1.41.11.3
Delay discount hyperbolic model param0.00.00.1-0.00.0-0.00.1-0.10.20.2-0.10.1-0.10.10.20.20.20.2-0.2-0.3-0.30.40.3
Intermittent access intake day 1-15 change0.70.72.91.1-1.31.2-1.51.5-1.70.6-0.40.3-0.30.30.50.50.50.5-0.10.30.6-0.7-0.5
Intermittent access intake escalation0.70.73.10.9-1.21.1-1.41.4-1.80.4-0.20.2-0.10.10.30.40.40.40.10.50.9-0.9-0.8
Intermittent access intake escalation 20.70.72.40.2-0.40.4-0.60.7-1.3-0.30.6-0.50.6-0.6-0.3-0.4-0.3-0.30.91.21.5-1.5-1.4
Intermitt. access day 1 inactive lever presses0.40.51.3-0.00.1-0.1-0.50.6-0.0-0.40.8-0.90.8-0.8-0.5-0.5-0.5-0.50.81.01.1-1.1-1.1
Intermitt. access day 15 inactive lever presses0.20.20.5-0.70.5-0.50.6-0.70.4-0.40.5-0.70.5-0.5-0.4-0.4-0.3-0.30.40.30.4-0.2-0.2
Intermitt. access escalation Index1.10.92.70.3-0.20.20.1-0.20.40.8-1.01.0-1.01.00.80.90.80.8-1.2-1.4-1.51.61.6
Intermittent access day 1 total infusions2.42.73.81.9-1.71.7-1.61.6-1.31.7-1.71.9-1.81.81.71.61.61.6-1.7-1.6-1.51.41.4
Intermittent access day 15 total infusions4.44.99.52.9-2.92.8-3.13.1-2.92.2-2.02.2-2.02.02.22.12.12.1-1.8-1.3-0.90.70.9
Intermittent access terminal intake (last 3 days)4.34.76.82.6-2.52.5-2.52.4-2.42.2-2.12.4-2.22.22.22.12.22.2-2.0-1.7-1.41.51.5
Intermittent access total infusions2.62.84.82.2-2.02.0-2.22.2-1.81.8-1.51.8-1.51.51.81.61.71.7-1.5-1.2-0.90.90.9
Intermittent access day 1 locomotion2.12.23.91.8-1.61.6-2.02.0-1.11.8-1.31.2-1.31.31.81.61.71.7-1.3-1.2-1.01.01.0
Intermittent access day 15 total locomotion1.21.33.41.5-1.51.5-1.81.8-1.81.1-0.80.8-0.80.81.11.01.01.0-0.7-0.3-0.1-0.00.1
Intermittent access total locomotion0.81.02.41.2-1.11.1-1.51.5-0.81.2-0.60.7-0.60.61.31.01.21.2-0.7-0.5-0.30.50.4
Intermittent access standard deviation2.93.09.22.4-2.52.5-2.92.9-3.01.6-1.21.3-1.11.11.41.41.41.4-0.8-0.20.2-0.3-0.2
Left kidney weight0.10.30.90.8-0.80.8-0.70.7-0.90.3-0.60.6-0.60.60.20.30.20.2-0.4-0.2-0.2-0.20.1
Right kidney weight0.00.10.40.5-0.60.6-0.40.4-0.60.1-0.50.5-0.40.40.10.10.10.1-0.2-0.1-0.2-0.20.0
Cocaine induced anxiety2.52.94.2-1.71.8-1.81.3-1.31.6-1.52.0-2.02.0-2.0-1.5-1.5-1.5-1.51.81.71.8-1.4-1.6
Post-drug Anxiety0.80.91.3-1.11.1-1.11.1-1.10.9-0.91.0-0.91.0-1.0-0.8-0.9-0.9-0.90.90.70.7-0.5-0.6
Baseline Anxiety1.21.22.41.1-1.21.2-0.70.7-1.60.9-1.41.5-1.41.40.90.90.90.9-1.2-1.1-1.10.91.0
Tail length1.34.010.20.7-0.60.70.1-0.20.51.8-2.11.9-2.22.21.82.21.81.8-2.5-2.9-3.03.23.1
Length with tail0.52.06.10.00.1-0.00.6-0.71.01.0-1.31.2-1.41.41.11.41.11.1-1.7-2.1-2.32.52.4
Length without tail0.51.23.20.2-0.20.20.2-0.30.41.0-1.01.0-1.11.11.11.01.11.1-1.3-1.5-1.71.81.7
Times rat made contact with spout1.21.42.1-1.41.4-1.41.4-1.41.3-1.31.2-1.21.2-1.2-1.3-1.2-1.3-1.31.00.80.7-0.6-0.7
Lifetime Intake3.84.36.82.6-2.42.4-2.62.6-2.22.2-1.92.2-1.91.92.22.02.12.1-1.8-1.5-1.21.21.2
Liver weight, left0.10.20.8-0.40.4-0.40.6-0.70.90.1-0.20.1-0.20.20.30.20.30.3-0.4-0.6-0.80.80.7
Liver weight, right0.91.52.60.9-0.80.8-0.60.6-0.11.3-1.41.3-1.31.31.31.41.31.3-1.4-1.5-1.61.61.6
Locomotor activity0.71.11.51.1-1.01.0-1.00.9-0.81.2-1.11.1-1.01.01.21.11.21.2-1.0-1.0-0.90.90.9
Locomotor testing distance3.05.16.52.5-2.52.5-2.52.5-2.32.5-2.22.3-2.12.12.52.42.52.5-2.1-1.8-1.51.51.5
Locomotor testing rearing3.65.58.72.9-2.92.9-2.82.8-2.92.4-2.42.6-2.42.42.32.22.22.2-2.1-1.6-1.41.21.3
Locomotion in novel chamber0.70.92.81.0-1.00.9-1.61.6-1.70.30.2-0.20.1-0.10.30.00.20.20.61.01.3-1.4-1.3
Locomotion in novel chamber post-restriction0.30.40.6-0.60.6-0.60.4-0.40.3-0.70.8-0.70.7-0.7-0.7-0.7-0.7-0.70.70.70.7-0.7-0.7
Fecal boli incidents, locomotor time 10.40.50.8-0.80.7-0.70.7-0.70.8-0.70.7-0.90.7-0.7-0.6-0.7-0.6-0.60.60.50.5-0.5-0.4
Change in fecal boli incidents, locomotor task0.60.60.7-0.80.9-0.90.8-0.80.7-0.80.8-0.70.8-0.8-0.8-0.8-0.8-0.80.80.70.5-0.5-0.6
Time >=10cm from walls, locomotor time 10.40.40.9-0.70.7-0.70.7-0.71.0-0.70.5-0.50.6-0.6-0.7-0.7-0.7-0.70.50.40.3-0.3-0.3
Bouts of movement, locomotor time 10.60.61.5-1.01.1-1.11.1-1.11.2-0.80.7-0.80.7-0.7-0.7-0.6-0.7-0.70.60.40.3-0.1-0.2
Total resting periods, locomotor time 11.81.93.0-1.71.7-1.71.7-1.71.7-1.41.4-1.51.4-1.4-1.4-1.2-1.4-1.41.20.90.8-0.6-0.7
Rest time, locomotor task time 10.70.81.0-0.70.7-0.80.6-0.60.6-0.91.0-0.81.0-1.0-1.0-0.9-1.0-1.01.01.00.9-0.9-0.9
Distance moved, locomotor task time 11.21.41.71.3-1.31.3-1.11.1-1.21.2-1.31.3-1.31.31.21.11.21.2-1.2-1.0-1.00.80.9
Vertical activity count, locomotor time 11.31.31.61.2-1.21.2-1.11.0-1.01.2-1.21.1-1.31.31.21.21.21.2-1.2-1.1-1.01.01.0
Time >=10cm from walls, locomotor time 20.80.91.2-1.01.0-1.01.0-1.00.8-1.00.9-1.10.9-0.9-1.0-0.9-1.0-1.00.90.80.7-0.6-0.7
Bouts of movement, locomotor time 21.21.31.9-1.41.4-1.41.3-1.31.4-1.21.1-1.21.1-1.1-1.2-1.1-1.2-1.21.10.90.7-0.6-0.7
Total resting periods, locomotor time 20.80.81.5-1.11.2-1.21.1-1.11.2-0.90.9-0.90.9-0.9-0.9-0.9-0.9-0.90.80.60.5-0.4-0.5
Rest time, locomotor task time 21.21.31.7-1.21.2-1.21.1-1.01.1-1.21.3-1.21.3-1.3-1.1-1.2-1.1-1.11.21.11.0-0.9-1.0
Distance moved, locomotor task time 22.02.34.41.9-1.91.9-1.81.8-2.11.5-1.61.7-1.61.61.41.41.41.4-1.3-1.0-0.80.70.8
Vertical activity count, locomotor time 20.80.91.41.1-1.01.0-1.01.0-1.21.0-0.91.1-0.90.90.91.00.90.9-0.9-0.7-0.60.60.6
Light reinforcement 11.42.53.51.9-1.81.8-1.71.7-1.91.6-1.61.8-1.71.71.61.51.61.6-1.5-1.3-1.11.01.1
Light reinforcement 20.10.10.40.5-0.50.5-0.50.6-0.60.3-0.20.4-0.40.40.40.20.30.3-0.2-0.00.0-0.1-0.1
Bone: marrow area2.75.99.43.0-3.03.0-3.13.1-3.12.4-2.52.4-2.42.42.32.42.32.3-2.1-1.7-1.41.11.3
Bone: maximum diameter0.50.92.51.3-1.41.4-1.51.6-1.60.8-0.80.7-0.80.80.70.80.70.7-0.6-0.3-0.1-0.20.1
Bone: maximum force0.61.11.51.2-1.21.2-1.21.2-1.21.1-1.01.0-1.11.11.01.01.01.0-0.9-0.8-0.70.50.7
Bone: maximum moment0.71.21.91.3-1.41.3-1.41.4-1.41.1-1.01.0-1.11.11.01.11.01.0-0.9-0.7-0.60.40.5
Mean time between licks in bursts1.82.53.31.4-1.31.3-1.01.0-0.71.7-1.71.8-1.71.71.81.71.81.8-1.7-1.7-1.71.81.7
Mean num. licks in bursts0.00.10.2-0.30.3-0.30.4-0.50.4-0.10.0-0.00.0-0.0-0.1-0.1-0.1-0.1-0.0-0.1-0.20.20.2
Cd content in liver1.31.41.81.2-1.21.2-1.01.0-1.01.2-1.31.3-1.31.31.21.21.21.2-1.3-1.2-1.21.11.1
Co content in liver0.20.30.30.5-0.50.5-0.40.4-0.30.6-0.50.6-0.50.50.60.60.60.6-0.6-0.5-0.50.50.5
Cu content in liver2.73.34.6-2.12.1-2.12.1-2.12.0-1.91.8-1.91.8-1.8-1.9-1.9-1.9-1.91.71.41.2-1.1-1.2
Fe content in liver0.20.20.5-0.40.4-0.40.6-0.70.70.1-0.20.2-0.20.20.20.20.20.2-0.3-0.5-0.70.70.7
K content in liver0.20.20.7-0.20.3-0.30.5-0.50.60.2-0.30.3-0.30.30.20.20.20.2-0.4-0.6-0.70.80.7
Mg content in liver0.00.00.00.1-0.10.1-0.10.1-0.1-0.00.0-0.00.0-0.0-0.1-0.1-0.1-0.10.10.10.1-0.1-0.1
Mn content in liver1.31.52.6-1.51.6-1.51.6-1.61.6-1.21.2-1.01.2-1.2-1.2-1.2-1.2-1.21.00.70.6-0.4-0.5
Na content in liver0.10.10.30.3-0.30.3-0.40.4-0.6-0.0-0.00.0-0.00.0-0.1-0.1-0.1-0.10.10.20.3-0.4-0.3
Rb content in liver0.81.01.51.1-1.11.1-1.11.1-1.21.1-1.11.0-1.11.11.01.01.01.0-0.9-0.8-0.70.70.7
Se content in liver1.21.51.8-1.11.1-1.10.9-0.90.9-1.31.3-1.21.3-1.3-1.3-1.3-1.3-1.31.31.31.1-1.3-1.2
Sr content in liver2.01.82.21.3-1.41.4-1.21.2-1.11.5-1.41.4-1.41.41.51.51.51.5-1.4-1.3-1.21.31.2
Zn content in liver0.20.20.3-0.40.4-0.40.3-0.30.3-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.50.50.50.5-0.5-0.5
Bone: minimum diameter1.93.65.12.2-2.32.3-2.22.2-2.11.9-1.91.9-1.91.91.91.91.91.9-1.7-1.4-1.21.01.2
Time in familiar zone, hab. session 10.10.10.40.4-0.40.4-0.50.5-0.60.2-0.10.1-0.10.10.10.20.10.10.00.10.2-0.3-0.2
Time in novel zone, hab. session 10.20.20.7-0.70.7-0.70.8-0.80.8-0.40.4-0.30.4-0.4-0.3-0.4-0.3-0.30.30.10.00.10.0
Total zone transitions, hab. session 14.76.69.13.0-3.03.0-2.92.9-2.92.6-2.72.7-2.72.72.62.62.62.6-2.4-2.0-1.81.61.7
Total locomotion distance, hab. session 10.40.50.70.8-0.70.7-0.70.6-0.60.8-0.80.8-0.80.80.70.70.70.7-0.7-0.7-0.60.60.6
Locomotion velocity, hab. session 10.40.60.80.9-0.90.9-0.80.8-0.80.8-0.80.9-0.90.90.80.80.80.8-0.8-0.6-0.60.50.6
Time in familiar zone, hab. session 20.10.10.4-0.50.5-0.50.6-0.60.6-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.20.1-0.1-0.20.20.2
Time in novel zone, hab. session 20.40.40.7-0.40.4-0.40.2-0.20.2-0.60.7-0.70.7-0.7-0.6-0.6-0.6-0.60.70.80.8-0.8-0.8
Total zone transitions, hab. session 22.83.75.02.0-2.02.0-1.71.7-1.81.9-2.12.2-2.22.21.91.91.91.9-2.0-1.8-1.71.61.7
Total locomotion distance, hab. session 20.50.71.20.9-0.80.9-0.70.7-0.80.8-0.91.1-1.01.00.80.80.80.8-0.9-0.8-0.80.70.8
Locomotion velocity, hab. session 20.60.81.31.0-0.90.9-0.80.8-0.90.8-0.91.2-1.01.00.80.80.80.8-0.9-0.8-0.80.70.7
Novel to familiar place preference ratio0.00.00.20.3-0.30.3-0.40.4-0.40.10.0-0.00.0-0.00.00.10.00.00.10.20.3-0.3-0.3
Novelty place preference0.00.00.00.0-0.00.0-0.10.1-0.00.00.1-0.10.1-0.10.00.10.00.00.10.10.1-0.1-0.1
Time in novel zone, NPP test0.00.00.0-0.00.0-0.00.0-0.00.10.10.0-0.10.0-0.00.10.10.10.10.0-0.00.00.10.0
Total zone transitions, NPP test3.34.75.92.4-2.42.4-2.22.2-2.22.2-2.32.4-2.42.42.12.22.12.1-2.2-1.9-1.71.51.7
Total locomotion distance, NPP test0.20.31.00.8-0.80.8-0.80.9-1.00.4-0.50.6-0.50.50.30.40.30.3-0.3-0.1-0.0-0.1-0.0
Locomotion velocity, NPP test0.20.21.00.6-0.60.6-0.80.8-1.00.1-0.10.2-0.10.1-0.00.0-0.0-0.00.10.30.4-0.6-0.5
Intraocular pressure1.01.44.81.7-1.71.7-1.71.7-2.20.9-1.01.2-1.11.10.90.80.90.9-0.6-0.2-0.0-0.2-0.1
Delta distance traveled before/after self-admin4.24.65.92.1-2.02.0-1.81.8-1.42.4-2.22.2-2.22.22.42.42.42.4-2.3-2.2-2.12.12.1
Delta ambulatory time before/after self-admin2.62.84.01.6-1.51.5-1.51.4-1.01.9-1.71.7-1.61.62.01.92.02.0-1.8-1.7-1.61.71.6
Parametrial fat weight12.724.831.54.3-4.24.2-3.33.1-2.85.3-5.55.5-5.45.45.45.35.25.2-5.6-5.6-5.55.65.5
Pavlov. Cond. lever latency2.02.64.52.0-2.02.0-2.12.1-2.11.7-1.51.5-1.51.51.61.61.61.6-1.3-1.0-0.80.70.7
Pavlov. Cond. magazine entry latency2.73.57.4-2.42.5-2.42.7-2.72.7-1.91.7-1.71.6-1.6-1.8-1.8-1.8-1.81.40.90.6-0.5-0.6
Pavlov. Cond. change in total contacts2.52.63.3-1.71.7-1.71.7-1.61.4-1.81.7-1.61.6-1.6-1.8-1.7-1.8-1.81.61.51.3-1.3-1.3
Pavlov. Cond. index score1.82.35.3-2.02.0-2.02.3-2.32.3-1.51.3-1.31.2-1.2-1.4-1.4-1.4-1.41.00.60.4-0.2-0.3
Pavlov. Cond. latency score2.02.56.3-2.12.1-2.12.4-2.42.5-1.51.3-1.31.2-1.2-1.4-1.4-1.4-1.41.00.60.3-0.1-0.2
Pavlov. Cond. lever contacts1.41.63.3-1.61.6-1.61.8-1.81.8-1.31.1-1.11.1-1.1-1.3-1.2-1.3-1.30.90.60.4-0.4-0.4
Pavlov. Cond. magazine entry number1.62.03.61.7-1.71.7-1.91.9-1.81.5-1.31.2-1.21.21.41.41.41.4-1.2-0.9-0.70.60.6
Pavlov. Cond. intertrial magazine entries2.83.35.42.2-2.32.3-2.32.3-2.31.9-1.81.6-1.71.71.81.81.81.8-1.6-1.3-1.10.91.0
Pavlov. Cond. lever-magazine prob. diff.1.82.24.8-1.91.9-1.92.2-2.22.2-1.51.3-1.31.2-1.2-1.4-1.4-1.4-1.41.10.70.4-0.3-0.4
Pavlov. Cond. response bias1.82.24.4-1.91.9-1.92.1-2.12.0-1.61.3-1.31.3-1.3-1.5-1.4-1.5-1.51.10.80.6-0.5-0.5
Pavlov. Cond. lever latency1.92.53.91.2-1.21.3-0.90.9-0.71.7-1.81.5-1.71.71.71.81.71.7-1.9-1.9-1.92.01.9
Pavlov. Cond. magazine entry latency1.11.31.7-1.11.2-1.20.9-0.91.0-1.21.3-1.11.3-1.3-1.2-1.2-1.2-1.21.21.11.1-1.0-1.1
Pavlov. Cond. change in total contacts0.91.21.5-1.01.0-1.00.8-0.80.8-1.21.2-1.01.2-1.2-1.2-1.2-1.2-1.21.21.21.2-1.1-1.1
Pavlov. Cond. index score1.21.52.9-0.70.8-0.80.4-0.30.3-1.21.4-1.11.4-1.4-1.3-1.3-1.3-1.31.51.61.7-1.7-1.7
Pavlov. Cond. latency score1.41.73.5-0.70.7-0.80.3-0.20.2-1.31.5-1.21.4-1.4-1.3-1.3-1.3-1.31.61.81.8-1.9-1.8
Pavlov. Cond. lever contacts0.60.81.4-0.60.6-0.60.4-0.40.3-0.91.0-0.91.0-1.0-0.9-1.0-0.9-0.91.11.11.2-1.2-1.2
Pavlov. Cond. magazine entry number0.81.01.40.7-0.80.8-0.60.5-0.51.0-1.10.9-1.11.11.01.01.01.0-1.1-1.2-1.21.11.1
Pavlov. Cond. intertrial magazine entries1.01.31.61.0-1.01.0-0.80.8-0.61.3-1.21.2-1.31.31.31.21.31.3-1.3-1.3-1.21.31.2
Pavlov. Cond. lever-magazine prob. diff.1.21.62.9-0.80.8-0.80.5-0.40.4-1.31.4-1.21.4-1.4-1.3-1.3-1.3-1.31.51.61.7-1.7-1.7
Pavlov. Cond. response bias1.01.31.8-0.90.9-1.00.7-0.70.6-1.21.3-1.01.2-1.2-1.2-1.3-1.2-1.21.31.41.3-1.4-1.3
Time in closed arm before self-admin0.40.52.6-0.91.1-1.11.1-1.11.6-0.30.4-0.40.3-0.3-0.3-0.2-0.2-0.20.0-0.3-0.50.70.5
Time in closed arm after self-admin0.10.10.1-0.30.3-0.30.2-0.20.3-0.20.3-0.40.2-0.2-0.3-0.2-0.2-0.20.20.10.2-0.0-0.1
Time in open arm before self-admin1.11.23.1-0.60.4-0.40.3-0.2-0.4-1.11.0-1.01.0-1.0-1.2-1.1-1.3-1.31.31.51.6-1.8-1.6
Time in open arm after self-admin0.50.51.81.0-1.11.1-1.21.2-1.30.5-0.40.5-0.40.40.50.40.30.3-0.10.20.3-0.6-0.5
Bone: periosteal estimation1.12.44.72.0-2.12.0-2.22.2-2.21.5-1.41.4-1.51.51.41.41.41.4-1.2-0.8-0.60.30.6
Bone: periosteal perimeter0.71.22.51.4-1.51.5-1.61.6-1.61.0-1.00.9-1.11.11.01.01.01.0-0.9-0.6-0.40.20.4
Bone: post-yield work0.50.71.50.4-0.40.4-0.20.1-0.00.9-0.90.9-0.90.90.90.90.90.9-1.0-1.1-1.11.21.1
Progressive ratio test 1 active lever presses1.61.72.11.3-1.21.2-1.11.1-0.91.3-1.41.4-1.31.31.31.31.31.3-1.5-1.4-1.41.31.4
Progressive ratio test 1 breakpoint2.32.53.41.5-1.41.4-1.11.1-0.91.5-1.71.8-1.71.71.61.51.51.5-1.8-1.8-1.81.71.8
Progressive ratio test 1 inactive lever presses1.11.32.61.5-1.31.3-1.61.6-1.11.3-0.81.0-0.80.81.31.11.31.3-0.9-0.7-0.50.50.5
Progressive ratio test 2 active lever presses1.01.01.31.1-1.01.0-1.01.0-0.91.1-1.01.1-1.01.01.11.01.11.1-1.0-1.0-0.90.90.9
Progressive ratio test 2 breakpoint0.50.50.80.8-0.70.7-0.80.8-0.60.8-0.60.8-0.70.70.90.70.90.9-0.7-0.7-0.70.70.6
Progressive ratio test 2 inactive lever presses2.02.33.61.9-1.71.7-1.91.9-1.61.7-1.41.5-1.51.51.61.51.71.7-1.4-1.2-1.00.91.0
Incentive Sensitization - Responses0.10.10.30.4-0.20.2-0.40.40.00.5-0.20.2-0.30.30.50.30.50.5-0.4-0.4-0.40.40.4
Incentive Sensitization - Breakpoint0.10.10.20.4-0.20.2-0.40.4-0.00.4-0.20.2-0.30.30.50.30.50.5-0.3-0.3-0.30.40.3
Sum of active levers in priming session hrs 5-60.70.62.2-0.30.3-0.20.8-0.80.90.4-0.60.6-0.60.60.50.40.30.3-0.9-1.2-1.41.51.4
Progressive ratio0.50.61.41.0-1.11.1-1.01.0-1.20.6-0.90.9-0.80.80.60.60.60.6-0.7-0.5-0.40.20.3
Food seeking constrained by brief footshock0.10.10.3-0.30.2-0.20.3-0.3-0.1-0.50.3-0.30.4-0.4-0.5-0.3-0.5-0.50.40.40.5-0.5-0.4
Seeking ratio, punishment vs. effort1.01.31.9-1.31.4-1.41.3-1.31.4-1.01.2-1.31.2-1.2-1.0-1.0-1.0-1.01.10.90.9-0.6-0.8
Retroperitoneal fat weight0.10.51.30.9-0.90.9-1.11.1-1.10.6-0.60.4-0.40.40.60.60.60.6-0.4-0.2-0.1-0.00.1
Reaction time number correct0.10.10.4-0.10.2-0.2-0.10.00.60.50.1-0.2-0.10.10.50.40.60.6-0.2-0.3-0.30.50.3
Reaction time mean minus median0.60.81.4-0.70.6-0.60.5-0.50.2-1.10.8-0.80.8-0.8-1.0-1.1-1.1-1.11.01.11.0-1.2-1.1
Reaction time mean minus median AUC0.10.10.3-0.20.1-0.10.2-0.1-0.1-0.50.2-0.20.2-0.2-0.4-0.5-0.5-0.50.40.50.5-0.5-0.5
Reaction time num false alarms1.31.82.5-1.31.1-1.21.2-1.10.7-1.51.4-1.21.4-1.4-1.5-1.6-1.4-1.41.41.41.4-1.3-1.3
Reaction time num false alarms AUC1.01.42.0-1.11.0-1.01.0-0.90.5-1.31.3-1.21.3-1.3-1.3-1.4-1.2-1.21.31.31.4-1.2-1.3
Reaction time trials correct on left0.10.10.4-0.10.2-0.2-0.10.00.60.50.1-0.2-0.10.10.50.40.60.6-0.2-0.3-0.30.50.3
Reaction time trials on left0.10.10.3-0.10.2-0.2-0.10.10.60.40.1-0.2-0.10.10.50.40.60.6-0.2-0.2-0.20.50.3
Reaction time mean0.20.30.6-0.50.4-0.40.5-0.40.1-0.70.4-0.50.4-0.4-0.7-0.8-0.8-0.80.60.60.6-0.7-0.6
Reaction time mean AUC0.50.71.2-0.70.5-0.60.5-0.50.2-1.00.7-0.80.8-0.8-1.0-1.1-1.1-1.11.01.01.0-1.1-1.0
Median of all reaction times0.10.10.2-0.20.1-0.10.2-0.2-0.1-0.40.1-0.30.2-0.2-0.4-0.4-0.5-0.50.30.40.4-0.5-0.4
Reaction time omissions0.40.50.80.9-0.90.9-0.80.8-0.80.6-0.70.7-0.90.90.70.50.60.6-0.6-0.4-0.40.30.3
Reaction time false alarm rate0.81.21.9-0.90.8-0.80.9-0.90.2-1.31.1-0.81.1-1.1-1.3-1.4-1.3-1.31.21.21.2-1.2-1.2
Reaction time premature initiation rate1.51.94.4-1.81.9-1.91.8-1.82.1-1.31.4-1.51.4-1.4-1.1-1.2-1.2-1.21.10.70.5-0.3-0.5
Reaction time premature initiations1.11.54.7-1.71.8-1.81.6-1.62.2-0.91.3-1.41.2-1.2-0.7-0.9-0.8-0.80.90.50.3-0.0-0.2
Std. dev. reaction times1.31.82.6-1.21.1-1.11.1-1.00.7-1.51.3-1.41.3-1.3-1.5-1.6-1.6-1.61.51.51.4-1.5-1.4
Reaction time trials completed0.10.10.3-0.10.2-0.2-0.10.10.60.40.1-0.2-0.10.10.50.40.60.6-0.2-0.2-0.20.50.3
Reaction time trials AUC0.10.10.3-0.10.2-0.2-0.0-0.00.60.40.1-0.2-0.10.10.40.30.50.5-0.1-0.2-0.20.40.3
Run reversals in cocaine runway, females0.20.20.3-0.40.3-0.30.2-0.20.2-0.40.4-0.50.6-0.6-0.3-0.5-0.3-0.30.50.50.6-0.5-0.5
Run reversals in cocaine runway, males1.41.43.21.5-1.61.6-1.81.8-1.81.1-1.01.0-1.01.01.01.01.01.0-0.7-0.3-0.1-0.10.0
Latency to leave start box in cocaine runway0.10.10.3-0.40.2-0.20.5-0.50.1-0.4-0.0-0.00.1-0.1-0.4-0.3-0.4-0.40.10.00.0-0.1-0.0
Latency to leave start box in cocaine runway, F0.10.20.7-0.50.3-0.30.8-0.90.3-0.3-0.30.2-0.10.1-0.3-0.2-0.3-0.3-0.2-0.3-0.40.40.4
Latency to leave start box in cocaine runway, M0.20.20.30.6-0.50.5-0.50.5-0.50.5-0.40.5-0.40.40.50.50.50.5-0.4-0.3-0.30.30.3
Std. dev. time between licks in bursts0.60.71.00.8-0.70.7-0.70.6-0.41.0-0.91.0-0.90.91.01.01.01.0-0.9-0.9-0.80.90.9
Total sessions with >9 infusions2.83.13.92.0-2.02.0-1.91.8-1.51.9-1.81.9-1.71.71.91.71.81.8-1.8-1.6-1.51.31.4
Short access day 1 total inactive lever presses0.10.10.30.4-0.30.3-0.50.50.10.4-0.10.2-0.10.10.40.40.30.3-0.4-0.4-0.30.30.4
Short access day 10 total inactive lever presses0.20.20.7-0.50.6-0.60.4-0.40.9-0.30.6-0.60.6-0.6-0.3-0.4-0.3-0.30.40.30.3-0.2-0.3
Short access day 1 total infusions2.93.16.52.4-2.42.4-2.52.5-2.41.7-1.61.7-1.51.51.51.51.51.5-1.4-0.9-0.70.30.6
Short access day 10 total infusions1.71.92.81.7-1.61.6-1.61.6-1.41.5-1.31.5-1.31.31.51.31.41.4-1.3-1.1-0.91.01.0
Short access total infusions3.94.47.52.7-2.62.6-2.72.7-2.52.1-1.92.2-1.91.92.11.92.02.0-1.8-1.4-1.11.01.1
Short access day 1 locomotion0.80.82.21.2-1.31.3-1.41.5-1.50.8-0.70.7-0.70.70.80.60.70.7-0.5-0.2-0.1-0.20.0
Short access day 10 total locomotion0.50.62.11.1-0.90.9-1.41.5-0.70.9-0.30.4-0.30.30.90.90.90.9-0.4-0.20.00.00.0
Short access total locomotion0.60.61.91.0-1.01.0-1.41.4-0.80.9-0.40.5-0.40.40.90.70.80.8-0.4-0.2-0.0-0.00.1
One hour access (0.3 mA shock)1.72.02.81.7-1.61.6-1.61.6-1.51.5-1.31.5-1.31.31.61.41.51.5-1.3-1.1-1.01.00.9
Compulsive drug intake1.01.02.9-1.21.5-1.51.3-1.31.7-0.81.1-0.91.1-1.1-0.8-0.6-0.8-0.80.70.40.20.0-0.2
One hour access (shock baseline)2.52.94.22.0-2.12.1-2.02.0-2.01.8-1.71.8-1.71.71.81.51.81.8-1.5-1.2-1.00.90.9
Social response proportion1.11.14.9-1.31.6-1.61.8-1.82.2-0.30.5-0.40.4-0.4-0.1-0.3-0.1-0.1-0.1-0.6-0.91.41.0
Social responses2.12.74.91.2-1.11.1-0.70.7-0.61.7-1.71.9-1.81.81.81.71.81.8-1.9-2.0-2.12.22.1
Social time1.21.63.60.7-0.60.7-0.40.3-0.21.3-1.31.3-1.31.31.41.21.51.5-1.5-1.6-1.61.91.7
Soleus weight2.67.714.81.7-1.61.6-0.90.8-0.32.9-2.92.9-2.92.93.03.13.03.0-3.2-3.5-3.63.83.6
Bone: stiffness2.23.55.01.4-1.41.4-1.00.9-0.82.0-2.02.0-2.12.12.02.12.02.0-2.1-2.2-2.22.22.2
Tibialis anterior weight4.013.816.73.3-3.33.3-2.72.6-2.34.0-4.03.9-4.04.04.04.14.04.0-4.1-4.0-3.93.93.9
Time to tail flick, vehicle, before self-admin0.40.41.3-0.20.2-0.20.5-0.60.80.2-0.50.4-0.60.60.20.40.30.3-0.7-1.0-1.21.21.2
Time to tail flick, vehicle, after self-admin0.10.10.20.3-0.40.4-0.40.4-0.50.4-0.30.2-0.20.20.40.40.40.4-0.3-0.2-0.10.20.2
Time to tail flick, test, before self-admin3.63.56.6-2.42.4-2.42.3-2.32.6-1.82.0-1.91.9-1.9-1.6-1.7-1.7-1.71.61.21.0-0.7-0.9
Time to tail flick, test, after self-admin0.80.81.6-1.21.2-1.21.2-1.31.2-0.90.9-0.80.8-0.8-0.9-0.8-0.8-0.80.70.50.4-0.3-0.4
Delta time to tail flick, vehicle, before/after SA0.50.52.00.8-1.01.0-1.21.3-1.40.5-0.20.2-0.10.10.50.40.40.40.10.40.7-0.7-0.6
Delta time to tail flick, test, before/after SA1.51.32.61.5-1.51.5-1.41.4-1.61.0-1.21.3-1.21.20.91.01.01.0-1.0-0.7-0.60.30.5
Tibia length0.31.03.6-1.31.4-1.41.8-1.81.9-0.70.4-0.30.4-0.4-0.5-0.5-0.5-0.50.1-0.3-0.60.70.6
Ambulatory time before self-admin0.10.10.50.4-0.40.4-0.50.5-0.7-0.1-0.10.1-0.10.1-0.2-0.2-0.2-0.20.10.30.3-0.6-0.4
Ambulatory time after self-admin3.33.64.62.0-2.02.0-1.81.8-1.62.0-2.01.9-2.02.02.02.22.02.0-2.0-1.8-1.71.61.7
Bone: tissue strength0.10.10.30.3-0.30.3-0.40.5-0.5-0.1-0.0-0.1-0.00.0-0.1-0.1-0.1-0.10.10.30.3-0.5-0.4
Total heroin consumption1.11.24.1-0.30.5-0.51.0-1.01.60.5-0.80.8-0.80.80.60.50.60.6-1.2-1.6-2.01.91.9
Bone: trabecular number0.20.41.5-0.50.6-0.60.9-0.91.20.0-0.10.1-0.20.20.10.10.10.1-0.4-0.7-0.90.90.9
Bone: trabecular spacing0.10.21.00.5-0.50.5-0.70.7-1.00.1-0.00.00.0-0.00.10.10.10.10.20.40.5-0.5-0.5
Bone: trabecular thickness0.20.20.40.2-0.20.2-0.0-0.00.20.4-0.40.4-0.50.50.50.40.50.5-0.5-0.6-0.70.60.7
Bone: trabecular tissue density1.92.74.3-1.21.2-1.20.9-0.80.4-1.81.7-1.71.8-1.8-1.9-1.8-1.9-1.91.81.91.9-2.1-1.9
Water consumed over 24 hours3.54.26.9-2.62.6-2.62.6-2.62.6-2.12.0-2.12.0-2.0-2.0-2.0-2.0-2.01.71.21.0-0.8-0.9
Number of responses in last shaping day0.30.31.10.6-0.80.8-0.91.0-1.10.30.00.10.0-0.00.30.10.30.30.20.50.6-0.7-0.7