Ctsc

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Ctsc 0.44 0.27 4.8e-05 0.09 0.1 0.09 0.11 3.3e-03 2.1e-03 4.1e-03 1.4e-03
2 Brain isoform ratio NM_017097.2 0.06 0.04 1.7e-05 0.05 0.05 0.05 0.05 2.1e-05 3.4e-05 3.0e-05 3.3e-05
3 Brain isoform ratio XM_008759637.4 0.06 0.04 2.1e-05 0.05 0.05 0.05 0.05 2.6e-05 3.7e-05 3.4e-05 3.7e-05
4 Brain alternative polyA XM_008759637.4 0.06 0.04 3.7e-06 0.06 0.06 0.07 0.06 1.1e-06 1.4e-06 6.5e-07 1.0e-06
5 Brain alternative polyA NM_017097.2 0.06 0.04 4.5e-06 0.06 0.06 0.07 0.07 1.2e-06 1.5e-06 6.4e-07 8.5e-07
6 NAcc intron excision ratio chr1_151443766_151458158 0.02 0.01 4.0e-03 0.01 0.01 0.01 0.01 3.6e-02 1.0e-02 8.6e-03 1.1e-02
7 BLA isoform ratio NM_017097.2 0.06 0.05 9.2e-03 0.03 0.01 0.02 0.02 1.8e-02 7.5e-02 4.2e-02 4.8e-02
8 BLA isoform ratio XM_008759637.4 0.06 0.05 9.6e-03 0.02 0.01 0.01 0.01 1.8e-02 9.7e-02 5.6e-02 6.0e-02
9 Adipose intron excision ratio chr1_151443766_151448822 0.05 0.03 3.1e-05 0.02 0.03 0.02 0.02 2.6e-03 7.1e-04 5.5e-03 3.2e-03
10 NAcc alternative polyA XM_008759637.4 0.04 0.03 4.9e-06 0.04 0.04 0.04 0.04 1.1e-06 1.3e-06 1.0e-06 1.3e-06
11 NAcc gene expression Ctsc 0.13 0.06 0.0e+00 0.16 0.19 0.19 0.19 1.2e-23 2.3e-28 1.1e-27 9.0e-28
12 Eye gene expression Ctsc 0.34 0.16 9.4e-04 0.16 0.12 0.11 0.16 1.9e-03 6.0e-03 1.0e-02 1.8e-03
13 IC alternative polyA NM_017097.2 0.09 0.07 5.0e-03 0.06 0.02 0.04 0.05 1.6e-03 3.6e-02 6.6e-03 3.0e-03
14 IC alternative polyA XM_008759637.4 0.08 0.07 7.5e-03 0.05 0.02 0.03 0.05 2.6e-03 6.2e-02 1.7e-02 4.4e-03
15 NAcc alternative polyA NM_017097.2 0.04 0.03 9.3e-06 0.04 0.04 0.03 0.04 2.0e-06 3.9e-06 5.9e-06 3.7e-06
16 NAcc isoform ratio NM_017097.2 0.05 0.03 3.2e-07 0.05 0.04 0.05 0.05 2.9e-08 2.7e-07 9.5e-08 1.6e-07
17 NAcc isoform ratio XM_008759637.4 0.05 0.03 2.0e-07 0.05 0.04 0.04 0.04 1.5e-07 1.7e-07 1.7e-07 1.9e-07
18 NAcc intron excision ratio chr1_151443766_151448822 0.02 0.01 2.4e-03 0.01 0.01 0.01 0.01 1.7e-03 5.2e-03 5.7e-03 6.7e-03
19 Adipose intron excision ratio chr1_151443766_151458158 0.04 0.03 2.5e-04 0.02 0.03 0.02 0.03 6.0e-03 4.0e-04 2.0e-03 7.5e-04
20 LHb gene expression Ctsc 0.2 0.11 1.3e-04 0.12 0.13 0.13 0.14 1.2e-03 5.7e-04 5.1e-04 3.8e-04
21 PL gene expression Ctsc 0.21 0.1 0.0e+00 0.15 0.21 0.2 0.21 5.5e-16 1.0e-22 2.5e-21 3.4e-22
22 Adipose isoform ratio NM_017097.2 0.17 0.08 0.0e+00 0.12 0.16 0.16 0.16 6.1e-13 1.9e-17 4.9e-17 4.0e-17
23 Adipose isoform ratio XM_008759637.4 0.17 0.08 0.0e+00 0.13 0.17 0.16 0.16 7.3e-14 3.0e-18 2.4e-17 6.0e-18
24 BLA gene expression Ctsc 0.15 0.09 4.7e-06 0.11 0.08 0.12 0.1 2.3e-06 3.8e-05 7.4e-07 3.5e-06
25 PL isoform ratio XM_008759637.4 0.02 0.02 7.9e-03 0.02 0.02 0.01 0.02 4.6e-03 2.0e-03 1.6e-02 2.2e-03
26 PL isoform ratio NM_017097.2 0.02 0.02 8.3e-03 0.02 0.02 0.01 0.02 5.1e-03 2.0e-03 1.6e-02 2.3e-03
27 Adipose alternative polyA NM_017097.2 0.18 0.1 0.0e+00 0.18 0.19 0.18 0.19 7.4e-20 1.5e-20 6.0e-20 3.1e-20
28 PL alternative polyA NM_017097.2 0.03 0.02 5.7e-03 0.02 0.02 0.02 0.02 1.8e-03 1.7e-03 5.8e-03 3.2e-03
29 Adipose alternative polyA XM_008759637.4 0.19 0.1 0.0e+00 0.19 0.2 0.2 0.2 5.1e-21 1.0e-21 3.0e-21 1.7e-21
30 Brain gene expression Ctsc 0.28 0.1 0.0e+00 0.37 0.37 0.37 0.37 7.2e-36 1.3e-36 1.2e-35 1.3e-35
31 IC gene expression Ctsc 0.16 0.09 3.7e-07 0.09 0.13 0.12 0.12 1.9e-04 4.2e-06 8.6e-06 7.6e-06
32 PL alternative polyA XM_008759637.4 0.03 0.02 4.1e-03 0.02 0.02 0.02 0.02 1.3e-03 1.4e-03 2.6e-03 2.2e-03
33 pVTA gene expression Ctsc 0.25 0.11 0.0e+00 0.25 0.24 0.23 0.24 2.0e-20 1.1e-19 1.1e-18 2.8e-19
34 Liver alternative TSS NM_017097.2 0.04 0.02 2.0e-04 0.04 0.03 0.02 0.03 8.4e-05 3.7e-04 1.4e-03 4.5e-04
35 Liver alternative TSS XM_008759637.4 0.05 0.03 2.8e-05 0.04 0.04 0.03 0.04 9.7e-06 6.0e-05 1.3e-04 4.3e-05
36 Liver gene expression Ctsc 0.38 0.14 0.0e+00 0.25 0.26 0.25 0.26 8.3e-28 2.2e-29 2.0e-27 2.9e-28
37 Adipose gene expression Ctsc 0.79 0.08 0.0e+00 0.68 0.69 0.7 0.69 7.2e-104 2.9e-105 6.8e-108 1.1e-106

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
Bone: apparent density0.30.62.6-0.00.1-0.10.1-0.1-0.3-0.10.10.50.10.60.20.1-0.1-0.2-0.20.20.2-0.60.50.9-0.80.80.40.9-0.9-1.0-0.81.01.11.11.21.21.2-1.21.61.5
Area under the delay curve2.12.43.61.0-1.51.51.3-1.3-1.3-1.31.31.71.41.71.5-1.41.4-1.5-1.51.51.5-1.81.61.6-1.81.80.11.8-1.8-1.8-1.81.81.71.71.61.81.9-1.91.61.6
BMI with tail0.00.20.9-0.70.7-0.7-0.60.60.30.3-0.3-0.4-0.3-0.4-0.00.6-0.6-0.0-0.00.00.00.3-0.0-0.40.2-0.3-0.9-0.30.20.30.2-0.3-0.3-0.3-0.3-0.2-0.20.2-0.2-0.1
BMI without tail0.10.33.4-0.80.3-0.3-0.50.50.20.3-0.30.10.10.20.30.5-0.5-0.3-0.30.30.3-0.30.30.1-0.50.5-1.80.5-0.5-0.4-0.50.40.30.30.30.50.5-0.50.50.8
Body weight0.10.20.8-0.40.3-0.3-0.20.2-0.00.1-0.10.20.00.20.20.3-0.3-0.3-0.30.30.3-0.30.40.3-0.40.5-0.70.5-0.5-0.5-0.50.50.50.50.80.80.8-0.80.80.9
Weight adjusted by age0.20.20.6-0.80.8-0.8-0.70.70.60.7-0.7-0.4-0.6-0.4-0.60.7-0.70.60.6-0.6-0.60.3-0.5-0.30.2-0.2-0.6-0.20.20.10.2-0.1-0.1-0.1-0.10.20.0-0.00.40.2
Bone surface0.20.31.50.10.1-0.1-0.10.1-0.00.2-0.20.3-0.30.40.00.5-0.5-0.1-0.10.10.1-0.40.30.5-0.60.60.00.7-0.7-0.7-0.60.70.70.81.21.00.9-0.91.21.2
Bone volume0.20.31.4-0.10.1-0.1-0.10.1-0.10.1-0.10.3-0.10.40.20.3-0.3-0.2-0.20.20.2-0.40.40.5-0.60.6-0.10.7-0.6-0.7-0.60.70.70.81.01.00.9-0.91.21.2
Breakpoint value in progressive ratio session0.00.00.3-0.50.1-0.1-0.10.10.20.3-0.3-0.0-0.2-0.0-0.10.4-0.40.10.1-0.1-0.1-0.0-0.10.0-0.10.1-0.10.1-0.1-0.1-0.10.10.10.1-0.10.20.3-0.30.30.2
Number of licking bursts0.30.42.7-0.80.8-0.8-1.01.00.90.8-0.8-0.4-0.9-0.3-0.71.0-1.00.70.7-0.7-0.70.1-0.5-0.3-0.00.1-1.60.1-0.1-0.1-0.10.20.10.10.60.60.4-0.40.80.8
Context. condit. distance diff. score0.20.21.0-0.30.5-0.5-0.30.30.60.2-0.2-0.2-0.5-0.2-0.90.3-0.31.01.0-1.0-1.00.2-0.8-0.00.1-0.1-0.1-0.10.10.10.1-0.1-0.0-0.00.00.00.0-0.00.10.1
Locomotion velocity, session 113.314.322.04.5-4.74.74.4-4.4-4.5-4.04.03.94.43.84.7-4.04.0-4.7-4.74.74.7-3.74.43.5-3.53.43.13.3-3.3-3.2-3.33.23.13.12.22.72.6-2.61.61.7
Locomotion distance, session 10.50.61.90.1-0.80.80.7-0.7-1.1-0.90.90.51.40.61.2-1.21.2-1.3-1.31.31.3-0.51.10.5-0.50.5-0.00.4-0.4-0.4-0.50.30.40.3-0.10.00.2-0.2-0.30.1
Locomotion velocity, session 26.98.010.53.0-3.23.23.2-3.2-3.2-3.03.03.03.22.93.2-3.13.1-3.2-3.23.23.2-2.93.22.8-2.82.71.92.7-2.7-2.7-2.72.62.62.62.22.32.4-2.41.71.9
Locomotion distance, session 20.50.82.10.7-0.80.81.0-1.0-1.2-1.21.20.61.40.61.3-1.51.5-1.4-1.41.41.4-0.51.10.7-0.50.50.70.4-0.4-0.4-0.40.40.40.4-0.1-0.1-0.10.1-0.3-0.0
Locomotion velocity, session 33.43.96.61.9-2.02.02.1-2.1-2.4-2.12.12.02.52.02.5-2.02.0-2.6-2.62.62.6-1.92.41.9-1.81.81.31.8-1.8-1.7-1.71.61.71.71.31.41.5-1.50.91.1
Locomotion distance, session 37.48.112.53.5-3.23.23.1-3.1-3.0-2.82.83.12.83.03.1-2.92.9-3.1-3.13.13.1-3.03.22.8-2.92.91.92.8-2.8-2.8-2.82.82.72.72.72.42.5-2.51.92.0
Stereotopy head waving bouts, day 36.87.914.8-3.83.3-3.3-3.33.33.13.0-3.0-3.0-2.9-3.0-3.03.2-3.22.92.9-2.9-2.92.8-3.0-2.92.7-2.6-3.1-2.62.52.62.5-2.5-2.6-2.6-2.4-2.0-2.12.1-1.6-1.5
Stereotopy head waving duration, day 31.01.22.11.0-1.31.31.4-1.4-1.3-1.41.41.21.41.21.3-1.11.1-1.3-1.31.31.3-1.11.21.0-1.11.10.51.0-1.0-1.0-1.10.90.90.90.50.80.7-0.70.30.6
Locomotion velocity, session 73.43.76.22.5-2.12.12.2-2.2-2.2-2.42.42.12.42.12.1-2.32.3-2.1-2.12.12.1-2.02.02.0-1.91.91.41.8-1.8-1.8-1.81.81.81.71.21.21.1-1.10.71.1
Locomotion distance, session 72.73.47.02.6-1.91.92.1-2.1-2.2-2.22.21.92.01.91.9-2.42.4-1.9-1.91.91.9-1.71.92.0-1.61.62.61.5-1.5-1.6-1.41.61.71.71.41.00.9-0.91.11.0
Stereotopy head waving bouts, day 72.52.84.21.7-2.12.11.8-1.8-1.6-1.51.51.91.51.91.6-1.31.3-1.6-1.61.61.6-1.91.71.6-1.91.90.61.9-1.9-1.8-1.91.81.71.71.51.81.8-1.81.21.4
Stereotopy head waving duration, day 73.74.46.02.0-2.52.52.2-2.2-2.0-1.91.92.32.02.32.1-1.81.8-2.1-2.12.12.1-2.42.22.0-2.32.30.52.3-2.3-2.2-2.42.22.02.01.92.32.2-2.21.51.8
Locomotion velocity, session 86.37.612.63.1-3.23.23.3-3.3-3.2-3.23.22.93.42.82.9-3.53.5-2.9-2.92.92.9-2.72.92.9-2.52.52.82.4-2.4-2.4-2.42.32.52.51.91.91.9-1.91.31.5
Locomotion distance, session 80.30.41.0-0.80.9-0.9-0.70.70.80.4-0.4-0.6-0.5-0.6-1.00.2-0.21.01.0-1.0-1.00.7-1.0-0.40.6-0.6-0.4-0.60.60.60.6-0.6-0.5-0.5-0.5-0.6-0.50.5-0.4-0.3
Degree of sensitization distance2.82.93.6-1.61.9-1.9-1.71.71.71.4-1.4-1.8-1.6-1.8-1.81.2-1.21.81.8-1.8-1.81.9-1.9-1.61.8-1.8-0.6-1.81.81.71.8-1.7-1.7-1.7-1.6-1.7-1.81.8-1.4-1.4
Degree of sensitization stereotypy2.72.94.01.8-1.91.91.7-1.7-1.4-1.51.51.91.41.91.4-1.41.4-1.4-1.41.41.4-2.01.51.7-1.91.90.71.9-1.9-1.8-2.01.81.81.81.82.01.9-1.91.41.5
Conditioned locomotion1.92.24.6-1.40.9-0.9-1.01.01.11.1-1.1-1.5-0.7-1.5-1.11.0-1.01.11.1-1.1-1.11.6-1.4-1.61.7-1.7-0.4-1.81.81.81.7-1.8-1.8-1.8-2.1-1.9-1.91.9-1.9-2.0
Cocaine response after cond. corrected0.30.41.20.0-0.10.10.2-0.2-0.3-0.30.30.50.20.60.2-0.50.5-0.2-0.20.20.2-0.60.40.7-0.70.7-0.20.8-0.8-0.8-0.80.80.80.80.91.01.0-1.01.11.1
Cocaine response after cond. not corrected0.40.50.90.4-0.40.40.5-0.5-0.6-0.70.70.70.60.80.5-0.80.8-0.5-0.50.50.5-0.80.50.8-0.80.80.30.9-0.8-0.9-0.80.90.90.90.60.90.9-0.90.90.9
Cocaine response before conditioning0.20.20.6-0.30.3-0.3-0.40.40.60.4-0.4-0.4-0.5-0.4-0.70.5-0.50.80.8-0.8-0.80.4-0.8-0.40.4-0.40.2-0.40.40.40.4-0.4-0.4-0.4-0.6-0.3-0.40.4-0.2-0.4
Saline control response0.91.24.61.2-0.70.70.6-0.6-0.4-0.90.91.20.41.20.3-0.80.8-0.3-0.30.30.3-1.30.71.1-1.31.3-0.71.4-1.4-1.3-1.41.31.31.32.11.51.5-1.51.31.4
Bone: connectivity density0.40.63.6-0.20.4-0.4-0.10.10.00.2-0.20.4-0.40.4-0.10.5-0.50.10.1-0.1-0.1-0.50.20.8-0.70.70.40.8-0.8-0.9-0.71.01.11.11.31.21.2-1.21.91.7
Bone: cortical apparent density0.70.93.1-0.50.4-0.4-0.60.60.50.5-0.5-0.9-0.0-0.9-0.30.5-0.50.30.3-0.3-0.31.0-0.6-1.11.1-1.1-0.4-1.21.11.21.1-1.2-1.3-1.3-1.6-1.4-1.51.5-1.8-1.6
Bone: cortical area0.10.20.5-0.50.6-0.6-0.40.40.50.4-0.4-0.1-0.5-0.1-0.70.3-0.30.70.7-0.7-0.70.1-0.40.2-0.00.10.10.2-0.1-0.2-0.10.20.30.30.70.40.4-0.40.70.7
Bone: cortical porosity0.70.81.31.1-1.21.20.9-0.9-0.6-0.50.51.00.41.10.8-0.30.3-0.8-0.80.80.8-1.10.90.8-1.11.1-0.31.0-1.1-1.0-1.11.00.80.81.10.80.9-0.90.60.8
Bone: cortical porosity0.30.30.70.7-0.80.80.6-0.6-0.4-0.20.20.60.20.70.5-0.10.1-0.5-0.50.50.5-0.70.60.4-0.70.7-0.50.6-0.7-0.6-0.70.60.40.40.60.50.6-0.60.20.4
Bone: cortical thickness0.00.10.5-0.40.4-0.4-0.30.20.10.3-0.3-0.3-0.1-0.3-0.30.0-0.00.30.3-0.3-0.30.3-0.3-0.00.3-0.30.7-0.30.30.20.3-0.2-0.1-0.1-0.2-0.3-0.30.3-0.0-0.1
Bone: cortical thickness0.10.10.40.2-0.40.40.4-0.4-0.4-0.40.40.30.50.30.4-0.50.5-0.4-0.40.40.4-0.20.30.3-0.20.20.70.1-0.1-0.1-0.10.10.10.10.0-0.1-0.10.1-0.3-0.1
Bone: cortical tissue density0.71.03.2-0.50.4-0.4-0.60.60.60.5-0.5-0.9-0.1-0.9-0.40.5-0.50.40.4-0.4-0.41.0-0.7-1.21.1-1.1-0.4-1.21.21.31.1-1.3-1.3-1.4-1.7-1.5-1.61.6-1.8-1.6
Condit. Reinf. active minus inactive responses1.82.04.0-1.61.4-1.4-1.21.20.90.9-0.9-1.5-0.6-1.5-0.91.1-1.10.80.8-0.8-0.81.6-1.1-1.41.7-1.7-0.5-1.61.61.71.6-1.8-1.6-1.6-2.0-1.7-1.61.6-1.9-1.8
Condit. Reinf. active-inactive response ratio1.11.12.8-1.51.7-1.7-1.41.51.21.0-1.0-1.1-1.1-1.1-1.11.4-1.41.01.0-1.0-1.01.0-0.9-1.01.0-0.9-1.6-0.80.80.90.8-0.9-0.9-0.8-0.4-0.4-0.40.4-0.6-0.4
Condit. Reinf. active responses2.32.96.8-1.81.5-1.5-1.31.31.11.1-1.1-1.8-0.8-1.8-1.21.1-1.11.21.2-1.2-1.21.9-1.5-1.72.0-2.0-0.3-2.02.02.12.0-2.1-2.0-2.0-2.6-2.1-2.02.0-2.2-2.2
Condit. Reinf. inactive responses0.50.73.5-0.4-0.20.20.1-0.1-0.0-0.00.0-0.50.2-0.6-0.1-0.30.30.10.1-0.1-0.10.7-0.5-0.60.8-0.90.9-0.90.90.90.9-1.0-0.9-1.0-1.9-1.4-1.31.3-1.5-1.5
Incentive salience index mean0.40.51.8-0.70.6-0.6-0.40.40.10.2-0.2-0.70.1-0.7-0.10.4-0.40.10.1-0.1-0.10.8-0.4-0.60.9-0.90.4-0.90.90.90.9-1.0-0.8-0.8-1.4-1.0-1.01.0-1.2-1.1
Condit. Reinf. lever presses0.81.13.51.3-1.21.21.3-1.3-1.5-1.11.10.91.30.81.5-1.01.0-1.5-1.51.51.5-0.71.30.9-0.60.61.90.5-0.5-0.6-0.50.60.60.60.10.30.3-0.30.30.0
Condit. Reinf. active minus inactive responses0.40.53.20.2-0.40.40.3-0.3-0.4-0.50.5-0.20.8-0.20.6-0.30.3-0.6-0.60.60.60.30.3-0.50.5-0.5-0.2-0.60.50.70.5-0.8-0.8-0.8-1.1-1.1-1.11.1-1.8-1.3
Condit. Reinf. active-inactive response ratio0.91.15.00.0-0.30.30.3-0.3-0.5-0.40.4-0.50.9-0.60.5-0.50.5-0.5-0.50.50.50.80.0-0.71.0-1.00.7-1.11.11.21.1-1.3-1.2-1.2-2.0-1.8-1.71.7-2.2-2.0
Condit. Reinf. active responses0.30.42.10.3-0.50.50.5-0.5-0.7-0.70.70.11.00.10.8-0.60.6-0.8-0.80.80.8-0.00.6-0.10.1-0.1-0.4-0.20.20.40.1-0.4-0.4-0.4-0.6-0.7-0.60.6-1.5-0.9
Condit. Reinf. inactive responses0.30.41.90.3-0.10.10.1-0.10.0-0.20.20.6-0.00.60.10.1-0.1-0.0-0.00.00.0-0.70.30.5-0.70.8-1.00.8-0.8-0.7-0.90.70.70.71.41.11.0-1.00.70.9
Condit. Reinf. lever presses0.50.83.21.2-1.11.11.1-1.1-0.9-1.31.30.41.30.40.8-1.41.4-0.7-0.70.70.7-0.20.50.10.1-0.10.9-0.20.20.40.1-0.4-0.4-0.4-0.7-0.9-0.80.8-1.8-1.3
Condit. Reinf. lever reinforcers received0.20.31.80.3-0.40.40.5-0.5-0.6-0.80.80.21.00.20.6-0.70.7-0.6-0.60.60.6-0.10.4-0.00.1-0.1-0.3-0.10.10.30.0-0.3-0.3-0.3-0.5-0.5-0.50.5-1.3-0.8
Conditioned reinforcement - actives5.39.111.9-3.22.8-2.8-2.62.62.42.7-2.7-3.3-2.4-3.4-2.62.6-2.62.52.5-2.5-2.53.4-2.9-3.33.4-3.4-1.5-3.43.43.53.4-3.5-3.4-3.4-3.4-3.4-3.33.3-3.1-3.1
Conditioned reinforcement - inactives0.81.21.8-1.11.2-1.2-1.21.21.01.3-1.3-1.2-0.8-1.2-0.80.8-0.80.80.8-0.8-0.81.2-0.9-1.21.2-1.2-0.9-1.21.21.21.2-1.2-1.2-1.2-1.0-1.2-1.21.2-1.1-1.1
Conditioned locomotion2.32.96.6-1.41.0-1.0-0.90.90.70.8-0.8-1.8-0.8-1.9-0.90.9-0.90.90.9-0.9-0.92.0-1.3-2.02.1-2.10.3-2.22.22.32.1-2.3-2.3-2.2-2.5-2.4-2.42.4-2.6-2.4
Patch foraging indifference point 0 sec0.20.41.0-0.20.2-0.2-0.40.40.60.9-0.9-0.6-0.5-0.7-0.60.7-0.70.60.6-0.6-0.60.7-0.6-0.70.8-0.80.1-0.80.80.80.8-0.8-0.8-0.7-0.4-0.5-0.80.8-0.8-1.0
Patch foraging indifference point AUC0.50.71.90.7-0.40.40.5-0.5-0.3-0.60.60.90.20.90.1-0.30.3-0.1-0.10.10.1-1.00.31.0-1.11.1-0.21.1-1.1-1.1-1.11.21.11.11.21.31.2-1.21.41.4
Delay disc. indifference point, 0s delay0.80.93.6-1.91.2-1.2-1.31.31.31.2-1.2-0.7-0.9-0.6-1.21.4-1.41.21.2-1.2-1.20.5-1.1-0.50.3-0.3-1.9-0.20.20.20.2-0.1-0.2-0.2-0.30.00.2-0.20.60.6
Delay disc. indifference point, 16s delay1.71.92.81.5-1.71.71.4-1.4-1.3-1.51.51.51.41.51.5-1.61.6-1.5-1.51.51.5-1.51.51.2-1.41.40.51.4-1.4-1.3-1.51.31.11.11.21.11.1-1.10.50.8
Delay disc. indifference point, 2s delay1.31.52.60.6-1.01.01.0-1.0-0.9-1.01.01.31.01.30.9-0.90.9-0.9-0.90.90.9-1.31.01.4-1.41.40.31.4-1.4-1.4-1.41.41.51.51.31.61.6-1.61.51.4
Delay disc. indifference point, 24s delay1.51.72.41.3-1.51.51.3-1.3-1.2-1.41.41.41.31.41.4-1.61.6-1.4-1.41.41.4-1.41.41.3-1.41.40.41.3-1.3-1.3-1.41.31.21.21.21.31.2-1.20.80.8
Delay disc. indifference point, 4s delay1.01.03.8-0.6-0.10.1-0.10.10.20.0-0.00.80.30.80.1-0.10.1-0.1-0.10.10.1-1.00.30.9-1.21.2-1.91.3-1.3-1.3-1.31.31.31.31.21.61.8-1.82.01.7
Delay disc. indifference point, 8s delay1.82.12.61.2-1.51.51.4-1.4-1.5-1.41.41.51.51.51.6-1.41.4-1.6-1.61.61.6-1.51.61.5-1.51.50.81.5-1.5-1.4-1.51.41.41.41.21.51.5-1.51.11.2
Indifference point function ln k0.81.54.41.7-1.81.81.7-1.7-1.7-1.11.11.11.71.01.7-1.41.4-1.7-1.71.71.7-0.91.50.9-0.70.62.10.5-0.5-0.5-0.50.50.50.50.1-0.1-0.00.0-0.3-0.3
Indifference point function log k0.81.54.41.7-1.81.81.7-1.7-1.7-1.11.11.11.71.01.7-1.41.4-1.7-1.71.71.7-0.91.50.9-0.70.62.10.5-0.5-0.5-0.50.50.50.50.1-0.1-0.00.0-0.3-0.3
Patch foraging total patch changes 0 sec0.20.31.10.1-0.00.0-0.20.20.40.6-0.6-0.4-0.3-0.5-0.30.5-0.50.40.4-0.4-0.40.5-0.4-0.60.7-0.70.4-0.70.70.70.7-0.7-0.7-0.7-0.4-0.6-0.80.8-0.9-1.1
Patch foraging total patch changes 12 sec1.92.55.3-1.62.1-2.1-2.12.12.02.2-2.2-1.6-2.1-1.5-1.82.3-2.31.81.8-1.8-1.81.4-1.6-1.41.3-1.2-1.5-1.21.21.11.2-1.1-1.1-1.0-0.4-0.4-0.60.6-0.0-0.3
Patch foraging total patch changes 18 sec2.43.76.3-1.82.0-2.0-2.22.22.52.4-2.4-1.9-2.5-1.9-2.52.1-2.12.52.5-2.5-2.51.7-2.3-1.91.7-1.7-2.0-1.61.61.61.6-1.6-1.6-1.6-0.8-0.9-1.11.1-0.8-1.1
Patch foraging total patch changes 24 sec1.22.02.8-1.41.5-1.5-1.61.61.71.3-1.3-1.4-1.4-1.5-1.61.4-1.41.71.7-1.7-1.71.4-1.6-1.51.4-1.4-1.5-1.31.31.41.3-1.4-1.4-1.4-1.1-1.0-1.31.3-1.1-1.1
Patch foraging total patch changes 6 sec0.10.21.00.10.2-0.2-0.20.20.40.1-0.10.2-0.30.2-0.50.4-0.40.50.5-0.5-0.5-0.3-0.20.3-0.30.3-0.60.4-0.4-0.4-0.40.40.50.51.00.80.6-0.60.90.7
Patch foraging time to switch 0 sec3.16.313.2-3.63.6-3.6-3.63.63.43.0-3.0-2.5-3.4-2.4-3.22.9-2.93.13.1-3.1-3.12.1-2.8-2.11.7-1.7-3.5-1.51.51.41.5-1.3-1.4-1.4-0.6-0.5-0.50.50.40.1
Patch foraging water rate 0 sec1.93.910.93.1-2.82.82.9-2.9-2.6-2.52.52.02.61.92.2-2.32.3-2.1-2.12.12.1-1.62.01.9-1.31.33.31.2-1.2-1.1-1.11.11.21.30.80.50.4-0.4-0.3-0.1
Patch foraging water rate 12 sec4.69.722.34.6-4.34.34.3-4.3-4.1-4.24.23.04.12.93.7-3.93.9-3.6-3.63.63.6-2.53.22.7-2.12.04.71.9-1.8-1.8-1.81.71.81.80.90.50.7-0.7-0.5-0.1
Patch foraging water rate 18 sec13.721.135.86.0-5.75.75.9-5.9-5.9-5.75.74.65.94.55.7-5.45.4-5.6-5.65.65.6-4.15.24.3-3.73.65.73.4-3.4-3.3-3.43.23.33.32.01.91.8-1.80.61.1
Patch foraging water rate 24 sec4.66.513.63.1-3.13.13.3-3.3-3.3-3.13.12.63.32.53.0-2.92.9-3.0-3.03.03.0-2.22.82.6-2.01.93.71.9-1.8-1.9-1.81.82.12.11.31.21.2-1.20.80.9
Patch foraging water rate 6 sec3.55.115.83.3-3.03.03.2-3.2-3.0-2.62.62.32.92.12.6-2.82.8-2.5-2.52.52.5-1.92.42.2-1.61.54.01.4-1.4-1.4-1.41.41.51.51.00.60.7-0.70.10.2
Seeking ratio, delayed vs. immediate footshock0.50.61.20.5-0.80.80.9-0.9-1.0-0.80.80.91.10.90.9-0.90.9-0.9-0.90.90.9-0.80.90.8-0.80.80.00.8-0.8-0.8-0.80.80.80.80.40.80.6-0.60.50.5
Distance traveled before self-admin0.10.10.8-0.90.5-0.5-0.40.40.20.6-0.6-0.3-0.0-0.2-0.40.3-0.30.30.3-0.3-0.30.2-0.4-0.30.2-0.2-0.7-0.20.20.10.1-0.1-0.2-0.2-0.7-0.2-0.20.20.00.3
Distance traveled after self-admin0.60.72.7-1.41.2-1.2-1.11.10.91.2-1.2-0.6-0.9-0.5-1.01.2-1.21.01.0-1.0-1.00.4-0.9-0.40.2-0.2-1.6-0.10.10.10.1-0.0-0.0-0.00.10.30.4-0.40.70.7
Extensor digitorum longus weight0.00.10.2-0.40.0-0.00.2-0.10.0-0.20.20.20.30.2-0.30.3-0.30.30.3-0.3-0.3-0.2-0.20.3-0.20.2-0.10.3-0.3-0.2-0.20.20.30.30.10.30.3-0.30.10.3
Bone: elastic displacement0.10.21.60.0-0.00.00.2-0.2-0.30.2-0.2-0.20.1-0.30.20.2-0.2-0.2-0.20.20.20.40.1-0.10.4-0.41.3-0.50.50.40.5-0.4-0.3-0.3-0.6-0.5-0.60.6-0.4-0.7
Bone: elastic work0.10.10.8-0.1-0.20.20.3-0.3-0.50.0-0.00.00.5-0.00.50.2-0.2-0.5-0.50.50.50.10.40.10.1-0.10.9-0.10.10.10.2-0.1-0.00.0-0.3-0.1-0.10.1-0.1-0.2
Bone: endosteal estimation0.40.82.8-0.1-0.30.30.2-0.20.0-0.00.00.7-0.10.8-0.00.2-0.20.10.1-0.1-0.1-0.90.30.7-1.01.0-1.31.1-1.1-1.0-1.11.11.01.11.51.71.6-1.61.41.4
Bone: endosteal perimeter0.20.41.6-0.50.6-0.6-0.60.60.70.5-0.5-0.1-1.0-0.0-0.80.5-0.50.80.8-0.8-0.8-0.1-0.40.0-0.20.3-1.30.4-0.4-0.3-0.40.30.30.31.00.80.7-0.70.80.9
Epididymis fat weight0.20.72.0-1.11.1-1.1-1.11.11.01.4-1.4-0.9-1.1-0.9-1.00.9-0.91.01.0-1.0-1.00.9-0.9-0.70.8-0.80.6-0.70.70.60.8-0.6-0.6-0.5-0.4-0.3-0.30.30.2-0.1
Delta time in closed arm before/after self-admin2.82.63.41.5-1.71.71.7-1.7-1.6-1.41.41.81.71.81.6-1.61.6-1.6-1.61.61.6-1.81.61.8-1.81.80.91.7-1.7-1.8-1.71.81.81.81.21.51.4-1.41.41.5
Delta time in open arm before/after self-admin0.30.30.90.8-0.50.50.7-0.7-0.7-0.70.70.50.50.50.4-0.60.6-0.4-0.40.40.4-0.50.50.6-0.40.41.00.4-0.4-0.4-0.40.40.50.50.70.40.3-0.30.30.3
Diff in mean of infusions in LGA sessions1.51.83.70.5-1.11.11.1-1.1-1.0-0.80.81.41.01.41.0-0.80.8-1.0-1.01.01.0-1.51.21.4-1.51.60.31.6-1.6-1.6-1.61.61.61.61.51.91.9-1.91.71.6
Delay discount exponential model param2.12.33.5-1.01.5-1.5-1.31.31.31.3-1.3-1.6-1.4-1.6-1.51.4-1.41.51.5-1.5-1.51.7-1.6-1.61.7-1.7-0.2-1.71.71.71.7-1.7-1.7-1.7-1.6-1.8-1.91.9-1.6-1.5
Extinction: sum of active levers before priming0.30.40.9-0.50.2-0.2-0.20.20.30.5-0.5-0.6-0.3-0.6-0.40.4-0.40.40.4-0.4-0.40.6-0.6-0.60.6-0.60.5-0.70.70.70.7-0.7-0.8-0.8-0.9-1.0-1.01.0-0.9-0.8
Active lever presses in extinction session 61.81.83.6-1.10.9-0.9-0.80.80.91.0-1.0-1.4-0.9-1.4-1.01.0-1.01.01.0-1.0-1.01.5-1.3-1.31.6-1.60.8-1.61.61.61.7-1.6-1.5-1.5-1.9-1.8-1.71.7-1.6-1.8
Bone: final force0.30.52.1-0.40.2-0.20.1-0.1-0.4-0.40.40.50.60.60.2-0.20.2-0.3-0.30.30.3-0.60.51.0-0.80.8-0.20.9-0.9-0.9-0.80.91.11.11.11.11.1-1.11.21.4
Bone: final moment0.30.41.6-0.40.2-0.20.2-0.2-0.5-0.30.30.50.60.50.3-0.20.2-0.4-0.40.40.4-0.50.50.9-0.60.60.10.8-0.7-0.8-0.70.81.01.00.91.01.0-1.01.11.3
Food consumed during 24 hour testing period1.62.16.00.7-0.80.80.8-0.8-0.9-0.70.71.40.71.50.9-0.20.2-0.9-0.90.90.9-1.61.21.6-1.71.8-0.11.8-1.8-1.9-1.81.91.91.92.02.12.1-2.12.42.4
Glucose0.30.51.10.9-0.90.91.0-1.0-0.8-0.80.80.80.90.80.7-1.01.0-0.7-0.70.70.7-0.80.70.7-0.80.80.30.7-0.7-0.7-0.70.70.60.60.50.40.5-0.50.20.3
Heart weight0.60.92.41.1-0.90.91.0-1.0-1.3-1.21.20.31.30.31.5-1.11.1-1.6-1.61.61.6-0.21.20.10.0-0.11.2-0.20.10.20.1-0.3-0.3-0.3-0.5-0.9-0.70.7-1.2-1.0
Delay discount hyperbolic model param1.82.13.5-0.81.3-1.3-1.11.11.11.1-1.1-1.5-1.2-1.5-1.31.2-1.21.31.3-1.3-1.31.6-1.4-1.51.6-1.60.0-1.71.71.61.7-1.7-1.6-1.6-1.5-1.8-1.91.9-1.6-1.5
Intermittent access intake day 1-15 change0.61.23.5-0.50.4-0.4-0.10.1-0.10.4-0.4-0.90.1-1.0-0.20.3-0.30.10.1-0.1-0.11.2-0.5-0.91.4-1.41.3-1.41.41.51.5-1.5-1.3-1.3-1.8-1.8-1.81.8-1.9-1.8
Intermittent access intake escalation0.50.92.5-0.50.4-0.4-0.10.1-0.10.4-0.4-0.80.1-0.9-0.20.3-0.30.20.2-0.2-0.21.1-0.5-0.71.2-1.31.2-1.31.31.31.3-1.3-1.1-1.1-1.6-1.6-1.61.6-1.6-1.5
Intermittent access intake escalation 20.91.03.1-0.80.5-0.5-0.10.10.00.4-0.4-0.9-0.0-1.0-0.40.4-0.40.40.4-0.4-0.41.2-0.7-0.71.3-1.31.7-1.31.31.31.4-1.3-1.1-1.1-1.8-1.5-1.51.5-1.5-1.5
Intermitt. access day 1 inactive lever presses1.34.96.32.1-2.22.21.9-1.8-1.8-1.91.92.52.12.52.1-2.22.2-2.1-2.12.12.1-2.52.22.4-2.52.50.42.5-2.5-2.5-2.52.52.52.42.12.42.4-2.42.12.1
Intermitt. access day 15 inactive lever presses0.30.50.80.4-0.60.60.6-0.6-0.8-0.40.40.70.80.70.9-0.50.5-0.9-0.90.90.9-0.70.90.7-0.70.70.00.8-0.8-0.7-0.80.70.80.70.60.90.9-0.90.70.7
Intermitt. access escalation Index0.20.20.70.5-0.30.30.1-0.1-0.0-0.00.00.50.10.50.2-0.20.2-0.2-0.20.20.2-0.60.40.4-0.60.6-0.60.6-0.6-0.6-0.70.60.50.50.80.70.6-0.60.60.6
Intermittent access day 1 total infusions1.93.04.2-1.71.7-1.7-1.51.51.41.6-1.6-1.9-1.6-1.9-1.51.4-1.41.41.4-1.4-1.41.9-1.6-2.01.9-1.9-1.2-1.91.92.01.9-2.0-2.0-2.1-1.7-1.8-1.91.9-1.9-1.8
Intermittent access day 15 total infusions2.63.87.3-1.61.5-1.5-1.21.21.01.5-1.5-2.0-1.0-2.1-1.21.3-1.31.21.2-1.2-1.22.2-1.5-2.02.4-2.4-0.1-2.42.42.52.5-2.5-2.4-2.4-2.5-2.7-2.72.7-2.7-2.5
Intermittent access terminal intake (last 3 days)5.67.412.1-2.42.2-2.2-1.91.91.82.1-2.1-2.9-1.7-3.0-1.92.1-2.11.91.9-1.9-1.93.1-2.3-3.03.2-3.2-0.5-3.33.33.33.3-3.3-3.3-3.3-3.5-3.5-3.53.5-3.4-3.4
Intermittent access total infusions4.85.68.2-2.22.1-2.1-1.81.81.72.0-2.0-2.6-1.7-2.6-1.81.9-1.91.81.8-1.8-1.82.7-2.1-2.62.8-2.8-1.0-2.82.82.92.8-2.9-2.8-2.8-2.7-2.8-2.82.8-2.8-2.8
Intermittent access day 1 locomotion0.10.10.3-0.30.2-0.2-0.10.10.00.2-0.2-0.3-0.1-0.3-0.1-0.00.00.10.1-0.1-0.10.3-0.1-0.40.3-0.3-0.3-0.30.30.40.3-0.4-0.4-0.4-0.2-0.3-0.40.4-0.6-0.4
Intermittent access day 15 total locomotion0.40.63.70.3-0.80.81.1-1.2-1.2-0.90.90.31.20.20.9-1.01.0-0.9-0.90.90.90.00.50.20.3-0.31.9-0.30.30.40.4-0.4-0.2-0.2-0.9-0.6-0.70.7-1.1-1.0
Intermittent access total locomotion0.10.10.5-0.20.0-0.00.3-0.3-0.3-0.10.1-0.20.1-0.3-0.0-0.20.20.10.1-0.1-0.10.3-0.1-0.30.4-0.40.3-0.40.40.50.4-0.5-0.4-0.4-0.3-0.4-0.40.4-0.7-0.6
Intermittent access standard deviation2.04.25.8-2.11.9-1.9-1.81.81.62.1-2.1-2.3-1.6-2.3-1.62.0-2.01.61.6-1.6-1.62.4-1.8-2.22.4-2.4-0.6-2.42.42.42.4-2.4-2.3-2.3-2.2-2.3-2.22.2-2.1-2.3
Left kidney weight0.52.45.6-2.42.1-2.1-1.91.91.91.8-1.8-1.6-1.7-1.6-2.01.8-1.82.02.0-2.0-2.01.6-1.8-1.31.4-1.4-0.5-1.31.31.21.3-1.2-1.1-1.1-0.7-0.7-0.70.7-0.3-0.4
Right kidney weight0.10.52.3-1.51.0-1.0-0.80.80.70.9-0.9-0.3-0.5-0.3-0.90.8-0.80.80.8-0.8-0.80.2-0.60.00.1-0.0-0.20.1-0.1-0.1-0.00.20.30.30.40.70.7-0.70.90.9
Cocaine induced anxiety1.21.75.10.7-0.70.70.6-0.6-0.3-0.30.31.30.21.30.1-0.40.4-0.1-0.10.10.1-1.40.51.4-1.61.6-0.31.7-1.6-1.7-1.61.81.71.72.02.02.0-2.02.22.1
Post-drug Anxiety2.32.43.91.8-1.61.61.2-1.2-0.9-1.11.11.81.01.81.1-1.11.1-1.0-1.01.01.0-1.91.31.6-1.92.0-0.31.9-1.9-1.9-2.01.91.81.82.01.81.8-1.81.71.7
Baseline Anxiety4.14.79.73.1-3.03.02.6-2.5-2.6-2.72.72.22.92.13.0-2.62.6-3.0-3.03.03.0-2.02.71.7-1.81.71.21.5-1.6-1.4-1.61.41.31.20.60.60.6-0.6-0.30.1
Tail length0.41.42.70.5-1.01.00.9-0.8-0.8-0.60.61.21.01.30.9-0.40.4-0.9-0.90.90.9-1.41.11.2-1.41.4-0.61.5-1.5-1.4-1.51.51.41.41.51.61.6-1.61.41.6
Length with tail0.31.23.30.5-0.70.70.6-0.7-0.6-0.30.31.10.41.10.5-0.50.5-0.5-0.50.50.5-1.20.81.2-1.31.30.11.4-1.4-1.4-1.41.41.41.41.81.81.7-1.71.81.7
Length without tail0.20.62.00.9-0.40.40.6-0.6-0.5-0.50.50.80.20.70.3-0.60.6-0.2-0.20.20.2-0.70.50.9-0.80.81.00.8-0.8-0.9-0.80.91.01.01.41.11.1-1.11.21.0
Times rat made contact with spout0.70.82.00.4-0.50.50.3-0.3-0.2-0.30.30.80.20.90.40.2-0.2-0.3-0.30.30.3-1.00.60.8-1.11.1-1.01.1-1.1-1.2-1.21.21.01.01.31.31.4-1.41.41.4
Lifetime Intake5.56.79.5-2.52.3-2.3-2.12.11.92.2-2.2-2.8-1.9-2.9-2.02.2-2.22.02.0-2.0-2.02.9-2.3-2.83.0-3.0-1.1-3.03.03.13.0-3.1-3.0-3.0-3.0-3.1-3.13.1-3.0-3.0
Liver weight, left1.01.65.8-2.41.8-1.8-1.71.71.61.2-1.2-1.4-1.4-1.3-1.61.4-1.41.61.6-1.6-1.61.3-1.5-1.01.0-1.0-1.3-0.91.00.91.0-0.8-0.8-0.8-0.8-0.5-0.50.50.1-0.0
Liver weight, right0.20.31.2-1.10.8-0.8-0.60.60.50.5-0.5-0.2-0.2-0.1-0.60.6-0.60.50.5-0.5-0.50.1-0.30.3-0.10.10.20.2-0.2-0.3-0.20.30.40.40.50.40.6-0.60.91.0
Locomotor activity3.65.59.23.0-3.03.03.0-3.0-2.5-2.62.62.62.52.52.3-3.03.0-2.3-2.32.32.3-2.52.32.2-2.32.31.72.2-2.2-2.1-2.32.12.02.01.81.81.8-1.81.01.2
Locomotor testing distance1.11.95.32.3-2.22.21.9-1.9-1.5-1.51.51.51.41.41.5-1.61.6-1.4-1.41.41.4-1.41.41.1-1.21.21.01.1-1.1-1.0-1.21.00.90.91.00.80.8-0.80.10.0
Locomotor testing rearing0.30.73.31.8-1.41.41.2-1.1-0.9-0.30.30.90.80.81.1-0.80.8-1.1-1.11.11.1-0.81.10.5-0.60.60.30.5-0.6-0.4-0.60.40.30.30.70.20.2-0.2-0.4-0.3
Locomotion in novel chamber2.22.93.71.6-1.91.91.8-1.8-1.6-1.61.61.91.61.91.6-1.81.8-1.6-1.61.61.6-1.91.71.8-1.81.80.81.8-1.8-1.8-1.81.81.81.81.71.61.6-1.61.31.5
Locomotion in novel chamber post-restriction0.61.05.00.8-0.40.40.6-0.6-0.6-0.80.8-0.40.5-0.50.5-0.40.4-0.5-0.50.50.50.60.2-0.60.9-0.92.2-1.01.01.11.0-1.1-1.1-1.1-1.4-1.5-1.61.6-1.9-1.6
Fecal boli incidents, locomotor time 10.60.91.91.1-0.70.70.5-0.5-0.4-0.60.61.00.31.00.5-0.80.8-0.5-0.50.50.5-1.10.80.9-1.21.2-0.61.2-1.2-1.2-1.21.21.11.11.41.31.1-1.11.11.2
Change in fecal boli incidents, locomotor task0.30.30.9-0.50.5-0.5-0.40.40.40.3-0.3-0.6-0.2-0.6-0.50.5-0.50.50.5-0.5-0.50.6-0.6-0.60.7-0.7-0.0-0.70.70.70.7-0.7-0.6-0.6-0.9-0.8-0.70.7-0.6-0.7
Time >=10cm from walls, locomotor time 10.40.42.8-1.10.9-0.9-0.80.80.80.5-0.5-0.4-0.7-0.4-0.80.5-0.50.80.8-0.8-0.80.2-0.7-0.40.0-0.0-1.70.0-0.0-0.1-0.10.1-0.0-0.0-0.20.40.3-0.30.60.6
Bouts of movement, locomotor time 11.11.32.41.6-1.31.31.1-1.1-1.0-1.11.11.20.81.21.1-1.11.1-1.1-1.11.11.1-1.21.21.2-1.21.20.51.2-1.2-1.2-1.21.11.11.11.11.11.0-1.00.90.8
Total resting periods, locomotor time 10.91.01.81.4-1.11.11.1-1.1-1.0-1.11.11.10.81.11.0-1.01.0-1.0-1.01.01.0-1.01.01.1-1.01.00.81.0-1.0-1.0-0.91.01.01.00.90.90.8-0.80.70.6
Rest time, locomotor task time 10.40.42.11.4-0.60.60.8-0.8-0.8-0.70.70.60.20.60.6-0.60.6-0.6-0.60.60.6-0.60.70.6-0.60.61.30.6-0.6-0.6-0.50.60.60.60.80.50.4-0.40.50.6
Distance moved, locomotor task time 10.10.21.3-1.10.2-0.2-0.30.30.10.2-0.2-0.30.4-0.30.10.2-0.2-0.1-0.10.10.10.4-0.1-0.20.4-0.4-0.1-0.40.40.40.4-0.4-0.3-0.3-1.1-0.5-0.40.4-0.4-0.4
Vertical activity count, locomotor time 10.30.84.1-2.01.2-1.2-1.21.20.91.2-1.2-1.0-0.7-1.0-0.71.2-1.20.70.7-0.7-0.70.9-0.8-0.90.7-0.7-1.2-0.70.70.70.7-0.6-0.7-0.7-1.0-0.4-0.20.2-0.1-0.2
Time >=10cm from walls, locomotor time 20.40.64.0-0.60.9-0.9-0.80.80.90.8-0.8-0.3-1.0-0.2-1.00.7-0.71.11.1-1.1-1.10.0-0.8-0.2-0.20.3-2.00.3-0.3-0.3-0.30.40.20.20.50.40.5-0.51.01.1
Bouts of movement, locomotor time 20.60.91.91.4-1.11.10.8-0.8-0.7-1.01.01.00.51.01.0-1.01.0-1.0-1.01.01.0-1.11.10.8-1.01.0-0.61.0-1.0-0.9-1.00.90.80.81.41.11.0-1.00.60.5
Total resting periods, locomotor time 20.40.61.41.2-0.90.90.7-0.7-0.6-0.90.90.80.40.80.8-0.90.9-0.8-0.80.80.8-0.90.90.6-0.80.8-0.60.8-0.8-0.7-0.90.70.60.61.11.00.8-0.80.40.4
Rest time, locomotor task time 20.81.01.5-1.21.0-1.0-0.90.90.91.0-1.0-1.0-1.0-1.0-1.21.0-1.01.11.1-1.1-1.11.0-1.2-1.01.0-1.0-0.2-1.01.01.01.0-1.0-0.9-0.9-1.1-0.8-0.80.8-0.6-0.7
Distance moved, locomotor task time 20.20.30.7-0.80.8-0.8-0.70.70.60.8-0.8-0.5-0.5-0.5-0.50.9-0.90.50.5-0.5-0.50.5-0.5-0.30.3-0.3-0.0-0.30.30.20.3-0.2-0.2-0.2-0.5-0.3-0.10.10.30.2
Vertical activity count, locomotor time 22.53.56.8-2.32.5-2.5-2.52.52.22.5-2.5-2.0-2.5-1.9-2.12.6-2.62.02.0-2.0-2.01.7-1.9-1.81.5-1.5-2.1-1.41.41.31.4-1.3-1.4-1.3-0.8-0.7-0.50.50.0-0.3
Light reinforcement 15.914.422.9-4.84.5-4.5-4.64.64.54.0-4.0-4.1-4.4-4.0-4.44.3-4.34.44.4-4.4-4.43.8-4.3-3.73.6-3.5-3.3-3.43.43.33.4-3.3-3.3-3.2-2.5-2.4-2.42.4-1.6-1.9
Light reinforcement 214.221.834.7-5.95.5-5.5-5.25.25.04.4-4.4-5.1-5.1-5.1-5.15.2-5.25.05.0-5.0-5.05.0-5.0-4.64.8-4.7-2.6-4.64.64.54.7-4.4-4.3-4.2-3.8-3.7-3.73.7-2.4-2.8
Bone: marrow area0.30.72.6-0.1-0.20.20.1-0.10.10.0-0.00.7-0.20.7-0.10.3-0.30.10.1-0.1-0.1-0.80.20.7-0.90.9-1.41.0-1.0-1.0-1.11.00.91.01.51.61.5-1.51.31.3
Bone: maximum diameter0.10.10.6-0.20.1-0.10.0-0.00.2-0.10.10.2-0.10.2-0.5-0.10.10.50.5-0.5-0.5-0.2-0.20.4-0.30.3-0.10.4-0.4-0.4-0.40.40.50.50.80.60.5-0.50.50.6
Bone: maximum force0.30.51.6-0.1-0.10.10.3-0.3-0.6-0.40.40.60.60.60.4-0.40.4-0.5-0.50.50.5-0.60.71.0-0.70.80.20.9-0.9-0.9-0.80.91.01.11.11.11.1-1.11.21.2
Bone: maximum moment0.30.51.3-0.1-0.10.10.4-0.4-0.6-0.30.30.50.60.50.5-0.30.3-0.6-0.60.60.6-0.50.70.9-0.60.60.50.7-0.7-0.8-0.70.80.91.00.91.01.0-1.01.11.1
Mean time between licks in bursts3.58.511.4-2.83.1-3.1-3.43.43.03.0-3.0-3.2-3.1-3.2-2.52.8-2.82.42.4-2.4-2.43.1-2.6-3.43.0-3.0-2.7-3.03.03.12.9-3.0-3.2-3.2-2.5-2.7-2.82.8-2.5-2.5
Mean num. licks in bursts0.50.81.71.2-1.31.31.3-1.3-1.1-1.11.10.91.20.91.0-1.01.0-0.9-0.90.90.9-0.80.80.8-0.70.71.10.6-0.6-0.6-0.60.60.60.60.20.30.4-0.40.00.1
Cd content in liver3.03.34.3-1.71.8-1.8-1.91.92.01.9-1.9-1.9-2.1-1.9-1.91.7-1.71.91.9-1.9-1.91.9-1.9-2.01.9-1.9-1.5-1.81.81.91.8-1.9-1.9-1.9-1.3-1.5-1.51.5-1.6-1.6
Co content in liver0.10.12.7-0.10.0-0.0-0.40.40.50.2-0.2-0.1-0.40.0-0.20.1-0.10.20.2-0.2-0.2-0.1-0.2-0.3-0.20.2-1.60.1-0.2-0.1-0.20.1-0.1-0.20.0-0.0-0.10.1-0.20.2
Cu content in liver1.51.84.50.9-0.70.70.6-0.6-0.6-0.70.71.30.31.40.7-0.60.6-0.7-0.70.70.7-1.51.01.2-1.71.7-0.91.7-1.7-1.7-1.71.81.61.61.91.91.9-1.92.02.1
Fe content in liver0.40.52.1-1.00.8-0.8-0.90.90.60.9-0.9-0.8-0.6-0.7-0.21.0-1.00.10.1-0.1-0.10.7-0.3-0.90.6-0.6-1.5-0.60.60.70.6-0.7-0.8-0.8-0.7-0.7-0.70.7-0.6-0.3
K content in liver0.10.10.5-0.60.5-0.5-0.20.20.00.0-0.0-0.10.1-0.0-0.2-0.10.10.20.2-0.2-0.20.0-0.20.2-0.10.10.30.1-0.1-0.2-0.00.20.30.30.10.20.2-0.20.70.5
Mg content in liver2.02.04.00.8-0.90.91.0-1.0-1.1-1.21.21.41.11.41.0-1.41.4-1.0-1.01.01.0-1.51.21.6-1.61.60.21.7-1.7-1.7-1.61.71.81.81.81.91.9-1.92.01.9
Mn content in liver0.10.21.00.0-0.00.00.4-0.4-0.3-0.80.80.30.80.3-0.2-1.01.00.20.2-0.2-0.2-0.2-0.20.5-0.10.10.70.2-0.2-0.1-0.10.10.30.3-0.00.10.0-0.0-0.20.0
Na content in liver6.77.212.11.8-1.91.92.1-2.1-2.1-2.22.22.82.22.82.0-2.52.5-2.0-2.02.02.0-2.92.43.0-3.13.10.53.1-3.1-3.2-3.13.33.33.33.13.23.2-3.23.53.5
Rb content in liver0.20.21.1-0.40.5-0.5-0.30.3-0.10.1-0.10.20.10.20.10.3-0.3-0.2-0.20.20.2-0.30.30.4-0.40.4-0.90.5-0.5-0.5-0.50.50.60.60.90.70.7-0.70.91.1
Se content in liver0.50.64.0-0.20.1-0.10.1-0.1-0.20.0-0.00.60.00.60.0-0.00.0-0.0-0.00.00.0-0.70.20.9-0.80.90.60.9-0.9-1.1-0.81.11.11.21.01.31.3-1.32.01.6
Sr content in liver1.51.32.61.1-1.21.21.2-1.2-0.9-1.61.61.41.31.40.7-1.61.6-0.7-0.70.70.7-1.40.81.3-1.41.3-0.01.3-1.3-1.2-1.31.21.11.10.80.80.8-0.80.30.9
Zn content in liver0.10.10.5-0.00.1-0.1-0.10.10.20.1-0.10.1-0.10.1-0.10.3-0.30.10.1-0.1-0.1-0.2-0.00.2-0.20.30.20.3-0.3-0.3-0.20.30.40.30.40.40.4-0.40.70.5
Bone: minimum diameter0.61.24.2-1.21.4-1.4-1.31.31.31.3-1.3-0.5-1.7-0.4-1.31.4-1.41.31.3-1.3-1.30.2-0.8-0.2-0.10.2-2.00.3-0.3-0.3-0.30.40.30.31.31.01.0-1.01.61.4
Time in familiar zone, hab. session 10.10.10.4-0.20.6-0.6-0.40.40.40.1-0.1-0.2-0.4-0.2-0.6-0.20.20.60.6-0.6-0.60.2-0.5-0.00.1-0.20.0-0.10.10.10.2-0.1-0.0-0.0-0.0-0.3-0.20.20.00.1
Time in novel zone, hab. session 10.00.00.1-0.1-0.40.40.2-0.2-0.20.2-0.2-0.10.2-0.10.30.3-0.3-0.3-0.30.30.30.10.2-0.10.2-0.20.3-0.20.20.20.2-0.2-0.2-0.2-0.20.0-0.10.1-0.2-0.4
Total zone transitions, hab. session 16.38.814.52.8-3.23.23.5-3.5-3.5-3.33.33.13.83.13.2-3.43.4-3.2-3.23.23.2-2.93.13.2-2.92.92.62.8-2.8-2.8-2.72.72.92.91.92.12.2-2.21.72.0
Total locomotion distance, hab. session 121.931.052.0-7.26.6-6.6-6.66.56.26.1-6.1-6.1-5.7-6.0-6.15.7-5.76.06.0-6.0-6.05.8-6.0-5.55.4-5.4-4.9-5.25.25.15.3-5.0-5.0-5.0-4.5-4.3-4.14.1-2.8-3.1
Locomotion velocity, hab. session 122.832.253.8-7.36.7-6.7-6.76.76.26.2-6.2-6.3-5.7-6.2-5.95.8-5.85.85.8-5.8-5.86.0-5.9-5.85.6-5.5-5.3-5.45.45.35.4-5.2-5.2-5.2-4.7-4.6-4.44.4-3.2-3.3
Time in familiar zone, hab. session 20.10.10.4-0.10.3-0.3-0.30.30.00.3-0.3-0.1-0.2-0.10.20.2-0.2-0.2-0.20.20.20.00.30.0-0.10.1-0.20.1-0.1-0.2-0.10.20.20.20.40.20.3-0.30.60.4
Time in novel zone, hab. session 20.20.21.40.2-0.40.40.2-0.20.0-0.10.1-0.10.2-0.10.0-0.10.10.00.0-0.0-0.00.1-0.2-0.40.2-0.3-0.1-0.40.30.40.3-0.5-0.6-0.6-0.7-0.6-0.70.7-1.2-0.9
Total zone transitions, hab. session 22.53.25.11.6-2.12.11.9-1.9-2.0-2.02.01.82.21.92.2-2.22.2-2.2-2.22.22.2-1.82.01.7-1.81.70.71.7-1.7-1.6-1.71.61.51.50.91.21.2-1.20.60.9
Total locomotion distance, hab. session 227.636.163.3-8.07.1-7.1-7.27.26.76.6-6.6-6.6-6.1-6.5-6.26.3-6.36.16.1-6.1-6.16.3-6.2-6.15.8-5.8-5.7-5.65.65.65.6-5.5-5.5-5.5-5.1-4.7-4.64.6-3.4-3.5
Locomotion velocity, hab. session 225.233.760.9-7.86.8-6.8-6.96.96.46.3-6.3-6.4-5.9-6.3-6.06.0-6.05.95.9-5.9-5.96.1-6.0-5.95.7-5.6-5.5-5.55.55.45.5-5.4-5.3-5.3-4.9-4.6-4.44.4-3.3-3.4
Novel to familiar place preference ratio1.31.41.9-1.01.2-1.2-1.21.21.31.1-1.1-1.2-1.2-1.2-1.31.3-1.31.41.4-1.4-1.41.1-1.4-1.21.1-1.1-0.6-1.11.11.11.1-1.1-1.2-1.2-1.2-0.9-1.11.1-0.9-0.9
Novelty place preference0.91.01.4-0.80.9-0.9-0.90.91.00.9-0.9-1.0-0.9-0.9-1.01.0-1.01.11.1-1.1-1.11.0-1.1-1.11.0-1.0-0.3-1.01.01.01.0-1.0-1.1-1.1-1.2-1.0-1.11.1-1.0-0.9
Time in novel zone, NPP test0.80.81.5-0.60.7-0.7-0.80.80.80.7-0.7-0.9-0.6-0.9-0.80.9-0.90.80.8-0.8-0.80.9-0.9-1.00.9-0.9-0.2-1.01.01.01.0-1.0-1.1-1.1-1.2-1.0-1.21.2-1.1-1.0
Total zone transitions, NPP test1.11.73.81.4-1.71.71.5-1.5-1.7-1.51.51.11.91.11.9-1.71.7-2.0-2.02.02.0-1.01.70.9-0.90.90.90.8-0.8-0.7-0.80.70.70.60.10.10.3-0.3-0.2-0.0
Total locomotion distance, NPP test32.244.069.8-8.47.7-7.7-7.77.76.97.2-7.2-7.4-6.5-7.3-6.46.7-6.76.26.2-6.2-6.27.2-6.5-6.96.8-6.7-5.7-6.66.66.56.6-6.5-6.4-6.4-6.0-5.7-5.65.6-4.3-4.5
Locomotion velocity, NPP test31.043.670.1-8.47.7-7.7-7.77.77.07.1-7.1-7.4-6.5-7.3-6.56.6-6.66.36.3-6.3-6.37.1-6.6-6.86.7-6.7-5.6-6.56.56.56.6-6.4-6.3-6.3-5.9-5.6-5.55.5-4.1-4.4
Intraocular pressure5.98.516.73.8-4.14.14.0-4.0-3.6-3.13.13.14.03.13.5-3.53.5-3.4-3.43.43.4-2.83.22.8-2.42.42.62.3-2.3-2.1-2.32.02.12.11.41.41.3-1.30.00.3
Delta distance traveled before/after self-admin0.40.51.6-0.40.9-0.9-0.90.90.90.8-0.8-0.6-1.3-0.6-0.91.0-1.00.80.8-0.8-0.80.5-0.6-0.50.4-0.4-0.9-0.30.30.30.3-0.3-0.3-0.30.60.20.1-0.10.30.1
Delta ambulatory time before/after self-admin0.60.72.2-0.61.1-1.1-1.11.11.21.0-1.0-0.8-1.5-0.8-1.11.2-1.21.11.1-1.1-1.10.7-0.9-0.70.7-0.7-0.6-0.60.60.60.6-0.5-0.5-0.50.4-0.0-0.10.10.1-0.2
Parametrial fat weight0.41.02.41.5-1.31.31.2-1.2-1.1-1.61.61.01.11.01.1-1.31.3-1.0-1.01.01.0-0.90.91.0-0.90.81.50.7-0.7-0.8-0.70.80.80.70.30.10.2-0.20.20.3
Pavlov. Cond. lever latency1.72.23.8-1.91.4-1.4-1.51.51.81.4-1.4-1.5-1.5-1.5-1.91.3-1.31.91.9-1.9-1.91.4-1.9-1.41.4-1.4-1.5-1.31.31.41.3-1.4-1.4-1.3-1.2-1.1-1.11.1-1.0-1.0
Pavlov. Cond. magazine entry latency0.20.30.90.4-0.00.00.0-0.0-0.5-0.20.2-0.20.6-0.20.9-0.30.3-0.9-0.90.90.90.20.6-0.30.3-0.30.3-0.40.40.40.4-0.4-0.4-0.5-0.7-0.6-0.60.6-0.8-0.7
Pavlov. Cond. change in total contacts0.10.10.60.30.2-0.2-0.10.1-0.1-0.00.00.2-0.00.20.2-0.00.0-0.2-0.20.20.2-0.20.30.4-0.30.30.40.4-0.3-0.4-0.30.40.50.50.70.60.6-0.60.80.6
Pavlov. Cond. index score0.70.92.61.3-0.70.70.8-0.8-1.3-0.90.90.71.20.71.6-0.90.9-1.6-1.61.61.6-0.71.50.7-0.60.61.00.6-0.6-0.6-0.60.50.60.50.40.30.3-0.30.20.2
Pavlov. Cond. latency score0.70.82.51.3-0.70.70.8-0.8-1.2-0.90.90.81.10.81.5-0.90.9-1.6-1.61.61.6-0.71.40.7-0.60.61.00.6-0.6-0.6-0.60.60.60.60.30.30.3-0.30.20.3
Pavlov. Cond. lever contacts0.81.01.91.4-0.70.70.8-0.8-1.1-0.80.81.00.91.01.3-0.70.7-1.3-1.31.31.3-1.01.31.0-1.01.00.90.9-0.9-1.0-0.91.01.01.00.90.80.9-0.90.90.9
Pavlov. Cond. magazine entry number0.30.31.2-0.80.3-0.3-0.40.40.80.6-0.6-0.1-0.8-0.1-1.10.6-0.61.11.1-1.1-1.10.0-0.9-0.0-0.00.1-0.80.1-0.1-0.1-0.10.20.10.20.30.40.5-0.50.60.5
Pavlov. Cond. intertrial magazine entries0.30.30.9-0.1-0.20.20.2-0.20.3-0.30.30.5-0.10.5-0.6-0.40.40.60.6-0.6-0.6-0.5-0.40.6-0.60.6-0.30.7-0.6-0.7-0.60.70.70.70.70.90.9-0.90.90.8
Pavlov. Cond. lever-magazine prob. diff.0.81.02.41.3-0.70.70.8-0.8-1.3-0.90.90.91.10.91.5-0.90.9-1.6-1.61.61.6-0.81.50.8-0.80.80.90.8-0.8-0.8-0.80.80.80.80.80.70.6-0.60.60.6
Pavlov. Cond. response bias0.10.20.80.6-0.10.10.2-0.2-0.6-0.30.30.10.50.10.8-0.20.2-0.9-0.90.90.9-0.10.80.1-0.10.10.60.0-0.0-0.1-0.00.10.10.10.1-0.0-0.10.1-0.0-0.1
Pavlov. Cond. lever latency0.70.95.2-1.00.8-0.8-0.70.70.30.7-0.70.1-0.50.2-0.20.9-0.90.20.2-0.2-0.2-0.40.20.5-0.70.7-1.20.8-0.8-1.0-0.81.01.01.01.31.51.5-1.52.32.0
Pavlov. Cond. magazine entry latency0.20.22.10.9-0.50.50.5-0.5-0.2-0.60.60.20.30.10.0-0.80.80.10.1-0.1-0.1-0.0-0.10.10.1-0.21.5-0.20.20.20.2-0.2-0.2-0.2-0.4-0.5-0.50.5-0.7-0.7
Pavlov. Cond. change in total contacts0.50.84.40.00.1-0.1-0.10.10.2-0.20.2-0.60.2-0.6-0.3-0.40.40.30.3-0.3-0.30.7-0.5-0.80.9-1.00.3-1.01.01.21.0-1.2-1.1-1.1-1.3-1.5-1.41.4-2.1-1.8
Pavlov. Cond. index score0.40.63.10.9-0.70.70.7-0.7-0.5-0.80.80.10.7-0.00.4-1.01.0-0.3-0.30.30.30.20.1-0.20.4-0.51.3-0.50.50.70.5-0.7-0.7-0.7-1.0-1.2-1.11.1-1.8-1.5
Pavlov. Cond. latency score0.40.52.51.0-0.70.70.7-0.7-0.5-0.80.80.10.70.10.4-0.90.9-0.4-0.40.40.40.10.1-0.10.3-0.41.4-0.50.50.60.4-0.6-0.6-0.6-0.9-1.0-1.01.0-1.6-1.4
Pavlov. Cond. lever contacts0.60.84.31.0-0.80.80.8-0.7-0.3-0.80.8-0.00.5-0.10.2-1.01.0-0.1-0.10.10.10.3-0.2-0.40.5-0.61.3-0.70.70.80.6-0.9-0.9-0.9-1.2-1.4-1.31.3-2.1-1.8
Pavlov. Cond. magazine entry number0.91.13.8-1.61.4-1.4-1.41.41.21.5-1.5-0.9-1.4-0.9-1.01.7-1.71.01.0-1.0-1.00.7-0.8-0.70.5-0.4-1.9-0.40.40.30.4-0.2-0.3-0.30.20.20.2-0.20.80.6
Pavlov. Cond. intertrial magazine entries0.30.41.50.1-0.30.30.1-0.1-0.2-0.10.10.5-0.10.60.50.2-0.2-0.5-0.50.50.5-0.70.60.4-0.80.8-1.20.8-0.8-0.8-0.90.80.60.60.81.00.9-0.91.01.1
Pavlov. Cond. lever-magazine prob. diff.0.40.63.00.9-0.70.70.6-0.6-0.4-0.70.70.10.6-0.00.3-1.01.0-0.3-0.30.30.30.20.0-0.20.4-0.41.2-0.50.50.60.5-0.7-0.7-0.7-1.0-1.1-1.11.1-1.7-1.5
Pavlov. Cond. response bias0.60.84.31.0-0.80.80.8-0.8-0.4-1.01.00.10.70.00.2-1.21.2-0.1-0.10.10.10.2-0.1-0.30.4-0.51.3-0.60.60.70.5-0.8-0.8-0.8-1.2-1.3-1.31.3-2.1-1.7
Time in closed arm before self-admin0.60.81.2-0.60.8-0.8-1.01.01.00.9-0.9-1.0-1.1-1.0-0.80.9-0.90.80.8-0.8-0.80.9-0.8-1.10.9-0.9-0.9-0.90.91.00.9-1.0-1.0-1.0-0.7-0.9-0.80.8-1.0-0.8
Time in closed arm after self-admin0.00.00.3-0.3-0.10.1-0.10.10.10.2-0.2-0.00.1-0.00.00.0-0.0-0.0-0.00.00.00.0-0.1-0.10.0-0.0-0.1-0.10.10.10.0-0.1-0.1-0.1-0.6-0.0-0.10.1-0.2-0.0
Time in open arm before self-admin0.10.10.20.1-0.10.10.2-0.2-0.2-0.20.20.20.20.20.2-0.30.3-0.2-0.20.20.2-0.30.20.2-0.30.3-0.20.3-0.3-0.3-0.30.40.30.30.30.30.2-0.20.40.5
Time in open arm after self-admin1.41.52.01.1-1.11.11.3-1.3-1.3-1.31.31.31.11.31.0-1.21.2-1.0-1.01.01.0-1.31.21.4-1.31.31.01.3-1.3-1.3-1.31.31.41.41.41.31.3-1.31.31.2
Bone: periosteal estimation0.30.72.8-0.30.1-0.1-0.10.10.30.2-0.20.5-0.40.6-0.40.4-0.40.40.4-0.4-0.4-0.70.00.7-0.80.8-0.91.0-1.0-1.0-1.01.01.01.11.71.61.5-1.51.61.5
Bone: periosteal perimeter0.10.20.8-0.20.3-0.3-0.20.20.50.3-0.30.0-0.70.1-0.70.2-0.20.70.7-0.7-0.7-0.1-0.40.2-0.20.2-0.20.3-0.2-0.3-0.20.30.30.30.90.50.4-0.40.60.6
Bone: post-yield work1.31.92.51.2-1.31.31.3-1.3-1.4-1.01.01.41.11.31.5-1.21.2-1.5-1.51.51.5-1.41.61.4-1.41.41.01.4-1.4-1.4-1.41.41.41.51.51.51.5-1.51.41.3
Progressive ratio test 1 active lever presses0.81.03.0-0.70.6-0.6-0.40.40.20.4-0.4-1.0-0.2-1.0-0.40.3-0.30.40.4-0.4-0.41.1-0.7-1.11.2-1.20.0-1.31.31.31.2-1.4-1.3-1.3-1.6-1.5-1.61.6-1.7-1.5
Progressive ratio test 1 breakpoint0.81.03.0-0.70.6-0.6-0.30.30.20.4-0.4-1.0-0.1-1.0-0.30.3-0.30.30.3-0.3-0.31.1-0.6-1.01.2-1.20.0-1.21.21.31.2-1.3-1.3-1.3-1.6-1.5-1.61.6-1.7-1.5
Progressive ratio test 1 inactive lever presses0.00.00.30.0-0.10.10.1-0.1-0.20.1-0.10.10.30.10.3-0.20.2-0.3-0.30.30.3-0.00.20.00.0-0.0-0.6-0.00.00.10.0-0.1-0.0-0.0-0.10.0-0.10.1-0.2-0.3
Progressive ratio test 2 active lever presses0.70.81.9-0.90.7-0.7-0.40.40.40.5-0.5-0.9-0.4-1.0-0.70.3-0.30.70.7-0.7-0.71.0-0.8-0.91.1-1.10.1-1.11.11.21.1-1.2-1.1-1.1-1.2-1.2-1.21.2-1.4-1.2
Progressive ratio test 2 breakpoint0.70.81.9-0.90.7-0.7-0.30.30.30.4-0.4-0.9-0.3-0.9-0.60.3-0.30.70.7-0.7-0.71.0-0.8-0.91.1-1.10.2-1.11.11.21.1-1.2-1.1-1.1-1.2-1.2-1.21.2-1.4-1.2
Progressive ratio test 2 inactive lever presses0.81.33.8-0.40.5-0.5-0.50.50.30.7-0.7-1.1-0.3-1.1-0.30.4-0.40.30.3-0.3-0.31.2-0.6-1.21.4-1.40.2-1.51.51.51.5-1.5-1.5-1.5-1.5-1.7-1.71.7-1.9-1.9
Incentive Sensitization - Responses0.10.10.4-0.40.4-0.4-0.30.30.40.3-0.3-0.3-0.5-0.3-0.60.1-0.10.60.6-0.6-0.60.3-0.5-0.20.3-0.3-0.1-0.20.20.30.3-0.3-0.2-0.20.1-0.1-0.10.1-0.1-0.1
Incentive Sensitization - Breakpoint0.20.20.5-0.60.5-0.5-0.40.40.50.4-0.4-0.4-0.6-0.5-0.70.3-0.30.70.7-0.7-0.70.5-0.6-0.40.5-0.5-0.0-0.40.40.50.5-0.4-0.4-0.4-0.1-0.3-0.30.3-0.2-0.3
Sum of active levers in priming session hrs 5-66.56.19.1-2.11.9-1.9-2.02.02.11.9-1.9-2.6-1.9-2.7-2.02.0-2.02.02.0-2.0-2.02.8-2.3-2.62.8-2.8-0.2-2.92.92.92.9-2.9-2.9-2.9-3.0-3.0-3.03.0-2.8-3.0
Progressive ratio0.91.53.3-0.90.7-0.7-1.01.00.90.9-0.9-1.2-0.8-1.3-0.60.9-0.90.60.6-0.6-0.61.3-0.9-1.61.4-1.4-0.8-1.41.41.51.3-1.5-1.6-1.7-1.5-1.4-1.61.6-1.8-1.8
Food seeking constrained by brief footshock2.63.15.5-1.61.8-1.8-2.02.01.71.9-1.9-2.0-1.8-2.0-1.32.1-2.11.21.2-1.2-1.21.9-1.3-2.21.9-1.9-2.4-1.81.81.91.8-1.9-2.0-2.0-1.2-1.7-1.51.5-1.5-1.7
Seeking ratio, punishment vs. effort0.50.71.9-0.91.2-1.2-1.21.21.11.2-1.2-0.8-1.3-0.7-1.11.2-1.21.11.1-1.1-1.10.6-0.9-0.60.4-0.3-1.4-0.30.30.20.3-0.2-0.2-0.20.2-0.10.3-0.30.60.5
Retroperitoneal fat weight0.20.72.3-1.01.2-1.2-1.51.51.21.5-1.5-0.8-1.2-0.8-0.80.9-0.90.80.8-0.8-0.80.6-0.6-0.80.5-0.5-1.0-0.40.40.40.4-0.4-0.5-0.50.20.10.1-0.10.40.2
Reaction time number correct1.83.410.11.9-2.42.42.6-2.6-2.5-2.52.51.82.51.72.2-2.02.0-2.1-2.12.12.1-1.61.91.8-1.31.33.21.3-1.3-1.3-1.21.21.31.40.50.80.9-0.90.40.4
Reaction time mean minus median0.10.32.2-0.20.4-0.4-0.60.60.31.0-1.0-0.5-0.5-0.50.30.5-0.5-0.3-0.30.30.30.30.2-0.70.3-0.3-1.5-0.40.30.40.3-0.4-0.6-0.6-0.2-0.4-0.30.3-0.4-0.3
Reaction time mean minus median AUC0.10.31.00.20.2-0.2-0.20.3-0.20.6-0.6-0.4-0.1-0.30.70.3-0.3-0.8-0.80.80.80.40.5-0.60.4-0.4-0.7-0.50.50.60.4-0.6-0.7-0.7-0.6-0.8-0.70.7-1.0-0.7
Reaction time num false alarms9.613.522.6-4.74.4-4.4-4.64.64.54.1-4.1-3.9-4.4-3.8-4.34.0-4.04.24.2-4.2-4.23.6-4.0-3.73.3-3.3-4.4-3.13.13.13.1-3.1-3.1-3.1-2.2-1.9-2.32.3-1.5-1.6
Reaction time num false alarms AUC6.710.518.0-4.23.8-3.8-4.04.04.03.6-3.6-3.4-3.9-3.4-3.83.5-3.53.83.8-3.8-3.83.1-3.6-3.32.9-2.9-3.9-2.72.72.72.7-2.7-2.7-2.7-1.8-1.6-2.02.0-1.3-1.4
Reaction time trials correct on left1.83.410.11.9-2.42.42.6-2.6-2.5-2.52.51.82.51.72.2-2.02.0-2.1-2.12.12.1-1.61.91.8-1.31.33.21.3-1.3-1.3-1.21.21.31.40.50.80.9-0.90.40.4
Reaction time trials on left1.83.49.81.9-2.42.42.6-2.6-2.5-2.52.51.82.51.72.2-2.02.0-2.1-2.12.12.1-1.51.91.8-1.31.33.11.3-1.3-1.2-1.21.21.31.30.50.80.8-0.80.40.4
Reaction time mean0.91.43.1-1.41.6-1.6-1.81.81.21.6-1.6-1.4-1.5-1.4-0.81.3-1.30.70.7-0.7-0.71.3-0.7-1.41.1-1.1-1.7-1.11.11.11.1-1.0-1.1-1.1-0.6-0.9-0.80.8-0.5-0.4
Reaction time mean AUC0.40.61.9-0.91.2-1.2-1.31.30.81.2-1.2-0.9-1.1-0.9-0.40.9-0.90.30.3-0.3-0.30.8-0.3-0.90.7-0.6-1.4-0.60.60.60.6-0.6-0.6-0.6-0.2-0.5-0.40.4-0.1-0.0
Median of all reaction times1.31.84.0-1.72.0-2.0-2.02.01.51.7-1.7-1.6-1.8-1.5-1.21.5-1.51.11.1-1.1-1.11.4-1.1-1.41.3-1.3-1.6-1.21.21.21.2-1.1-1.1-1.1-0.6-0.9-0.80.8-0.3-0.4
Reaction time omissions0.10.12.2-0.40.5-0.5-0.60.60.30.3-0.3-0.4-0.4-0.40.10.0-0.0-0.1-0.10.10.10.20.1-0.50.2-0.2-1.5-0.20.20.20.1-0.2-0.3-0.30.2-0.00.0-0.0-0.1-0.0
Reaction time false alarm rate9.913.621.7-4.54.4-4.4-4.74.64.64.3-4.3-3.8-4.6-3.8-4.44.0-4.04.44.4-4.4-4.43.5-4.1-3.73.2-3.2-4.5-3.03.03.03.0-2.9-3.0-3.0-1.9-1.8-2.22.2-1.3-1.5
Reaction time premature initiation rate0.10.20.50.4-0.30.30.3-0.3-0.4-0.70.70.40.20.30.4-0.50.5-0.4-0.40.40.4-0.40.50.4-0.30.3-0.10.4-0.4-0.4-0.40.40.40.40.60.50.4-0.40.30.4
Reaction time premature initiations0.91.63.91.4-1.51.51.6-1.6-1.7-2.02.01.21.51.21.6-1.51.5-1.6-1.61.61.6-1.11.51.2-0.90.91.40.9-0.9-0.9-0.90.80.90.90.70.70.6-0.60.30.4
Std. dev. reaction times0.10.34.1-0.10.2-0.2-0.50.50.00.6-0.6-0.2-0.3-0.10.70.2-0.2-0.8-0.80.80.80.00.7-0.5-0.00.0-2.00.0-0.10.0-0.1-0.0-0.2-0.30.2-0.10.0-0.0-0.10.2
Reaction time trials completed1.83.49.81.9-2.42.42.6-2.6-2.5-2.52.51.82.51.72.2-2.02.0-2.1-2.12.12.1-1.51.91.8-1.31.33.11.3-1.3-1.2-1.21.21.31.30.50.80.8-0.80.40.4
Reaction time trials AUC1.53.08.91.7-2.22.22.4-2.4-2.4-2.32.31.72.41.62.1-1.81.8-2.0-2.02.02.0-1.41.81.6-1.21.23.01.2-1.1-1.1-1.11.11.21.20.50.70.8-0.80.40.3
Run reversals in cocaine runway, females0.10.10.2-0.10.1-0.1-0.00.00.1-0.10.1-0.3-0.2-0.3-0.30.2-0.20.30.3-0.3-0.30.3-0.4-0.40.3-0.30.2-0.30.30.30.3-0.3-0.4-0.4-0.4-0.3-0.30.3-0.5-0.3
Run reversals in cocaine runway, males1.01.12.90.9-1.01.01.2-1.2-1.5-0.80.80.21.30.11.5-0.90.9-1.5-1.51.51.50.11.00.00.3-0.41.7-0.50.50.50.5-0.6-0.5-0.5-1.0-1.1-1.11.1-1.5-1.3
Latency to leave start box in cocaine runway3.74.313.3-3.02.7-2.7-2.92.92.82.8-2.8-1.8-3.0-1.7-2.62.8-2.82.52.5-2.5-2.51.3-2.2-1.60.9-0.9-3.6-0.80.80.70.7-0.6-0.8-0.8-0.20.20.3-0.31.10.9
Latency to leave start box in cocaine runway, F1.92.29.1-2.31.8-1.8-2.02.02.11.8-1.8-1.0-2.2-0.8-1.91.9-1.91.91.9-1.9-1.90.5-1.6-0.80.1-0.1-3.0-0.10.0-0.10.00.1-0.1-0.10.30.60.8-0.81.51.4
Latency to leave start box in cocaine runway, M5.24.98.5-2.72.8-2.8-2.82.82.62.9-2.9-2.3-2.8-2.3-2.42.9-2.92.42.4-2.4-2.42.1-2.2-2.12.0-2.0-2.4-1.81.81.81.8-1.8-1.8-1.7-1.2-1.0-1.11.1-0.5-0.9
Std. dev. time between licks in bursts2.33.15.7-1.82.1-2.1-2.22.22.32.1-2.1-1.8-2.4-1.8-2.22.0-2.02.22.2-2.2-2.21.6-2.0-1.71.5-1.5-1.6-1.41.41.41.4-1.4-1.4-1.4-0.7-0.8-0.90.9-0.4-0.7
Total sessions with >9 infusions10.012.214.8-3.83.5-3.5-3.43.43.23.1-3.1-3.8-2.9-3.8-3.03.3-3.33.03.0-3.0-3.03.8-3.3-3.83.8-3.8-2.4-3.83.83.83.8-3.8-3.8-3.8-3.8-3.7-3.73.7-3.4-3.4
Short access day 1 total inactive lever presses0.00.00.10.1-0.10.10.00.0-0.10.0-0.00.20.30.10.3-0.10.1-0.3-0.30.30.3-0.10.20.2-0.10.1-0.30.1-0.1-0.1-0.00.10.20.20.00.00.0-0.00.1-0.1
Short access day 10 total inactive lever presses1.74.08.81.7-1.41.41.3-1.3-1.3-1.11.12.11.02.11.3-1.21.2-1.3-1.31.31.3-2.21.72.2-2.32.30.92.4-2.4-2.5-2.32.52.52.52.92.72.9-2.93.02.7
Short access day 1 total infusions7.09.311.5-3.43.0-3.0-3.13.13.02.8-2.8-3.3-2.7-3.3-2.72.9-2.92.62.6-2.6-2.63.3-2.9-3.33.3-3.3-2.5-3.33.33.33.3-3.3-3.3-3.3-3.2-3.2-3.23.2-2.8-2.8
Short access day 10 total infusions2.12.63.7-1.71.5-1.5-1.31.31.11.5-1.5-1.8-1.2-1.8-1.11.5-1.51.11.1-1.1-1.11.8-1.3-1.81.9-1.9-1.0-1.91.91.91.9-1.9-1.9-1.9-1.8-1.9-1.91.9-1.8-1.8
Short access total infusions5.67.28.7-2.92.6-2.6-2.62.62.42.5-2.5-2.9-2.2-2.9-2.32.6-2.62.32.3-2.3-2.32.9-2.5-2.92.9-2.9-2.0-2.92.92.92.9-2.9-3.0-2.9-2.9-2.9-2.92.9-2.6-2.6
Short access day 1 locomotion1.01.22.8-1.71.2-1.2-1.11.11.11.1-1.1-1.2-0.9-1.2-1.21.1-1.11.21.2-1.2-1.21.2-1.2-1.01.1-1.1-1.2-1.11.11.11.1-1.0-1.0-1.0-0.9-0.9-0.90.9-0.7-0.7
Short access day 10 total locomotion0.20.50.70.6-0.70.70.8-0.8-0.8-0.60.60.70.70.60.8-0.80.8-0.8-0.80.80.8-0.60.80.6-0.60.60.50.6-0.6-0.6-0.60.50.60.60.80.70.8-0.80.40.4
Short access total locomotion1.61.92.9-1.71.4-1.4-1.31.31.11.3-1.3-1.6-1.1-1.6-1.11.2-1.21.11.1-1.1-1.11.5-1.2-1.61.5-1.5-1.1-1.51.51.61.5-1.6-1.6-1.6-1.4-1.4-1.41.4-1.4-1.3
One hour access (0.3 mA shock)3.23.77.8-1.41.3-1.3-1.01.01.01.1-1.1-2.0-1.1-2.1-1.31.1-1.11.31.3-1.3-1.32.2-1.6-2.22.3-2.40.2-2.42.42.52.4-2.5-2.5-2.5-2.6-2.6-2.62.6-2.8-2.7
Compulsive drug intake0.20.20.7-0.40.1-0.1-0.30.30.40.1-0.1-0.4-0.1-0.4-0.20.1-0.10.20.2-0.2-0.20.4-0.4-0.60.4-0.5-0.6-0.50.50.50.5-0.6-0.6-0.6-0.9-0.7-0.70.7-0.8-0.7
One hour access (shock baseline)1.32.04.5-0.90.9-0.9-0.50.50.40.6-0.6-1.4-0.6-1.5-0.80.7-0.70.80.8-0.8-0.81.6-1.1-1.51.8-1.80.7-1.81.81.91.8-1.9-1.8-1.8-1.8-2.0-2.02.0-2.1-2.1
Social response proportion0.10.20.60.8-0.60.60.5-0.5-0.50.2-0.20.30.40.30.7-0.40.4-0.7-0.70.70.7-0.20.50.1-0.10.10.40.1-0.1-0.1-0.10.10.00.0-0.2-0.1-0.10.1-0.1-0.2
Social responses0.20.20.90.8-0.60.60.5-0.5-0.70.1-0.10.10.60.10.9-0.20.2-0.9-0.90.90.9-0.00.70.00.1-0.10.3-0.20.20.20.2-0.2-0.2-0.2-0.3-0.3-0.30.3-0.5-0.6
Social time0.70.94.9-0.50.4-0.4-0.30.30.10.7-0.70.4-0.30.4-0.00.6-0.6-0.0-0.00.00.0-0.60.40.8-0.80.8-0.81.0-0.9-1.1-0.91.11.21.21.61.61.8-1.82.21.8
Soleus weight0.00.11.0-1.00.5-0.5-0.30.30.40.2-0.2-0.30.1-0.2-0.60.1-0.10.50.5-0.5-0.50.3-0.6-0.10.2-0.2-0.5-0.20.20.20.2-0.2-0.2-0.2-0.4-0.4-0.30.3-0.30.1
Bone: stiffness0.20.41.1-1.01.1-1.1-0.80.80.70.5-0.5-0.3-0.6-0.3-0.80.6-0.60.80.8-0.8-0.80.2-0.60.00.00.0-0.80.1-0.1-0.1-0.10.20.30.30.50.60.4-0.40.80.8
Tibialis anterior weight0.10.31.1-1.00.6-0.6-0.10.10.4-0.10.1-0.20.2-0.2-1.00.2-0.21.01.0-1.0-1.00.4-1.00.20.3-0.40.5-0.30.30.30.4-0.3-0.00.0-0.4-0.4-0.30.3-0.3-0.1
Time to tail flick, vehicle, before self-admin1.21.33.21.0-1.41.41.5-1.5-1.5-1.81.81.01.80.91.4-1.51.5-1.4-1.41.41.4-0.81.11.0-0.60.61.70.5-0.5-0.6-0.50.50.60.7-0.30.10.0-0.0-0.1-0.1
Time to tail flick, vehicle, after self-admin1.31.74.92.2-1.31.31.1-1.1-1.2-1.51.51.31.01.41.4-1.51.5-1.4-1.41.41.4-1.41.51.1-1.41.40.31.3-1.3-1.3-1.41.31.21.11.51.21.1-1.10.81.0
Time to tail flick, test, before self-admin1.21.32.01.4-1.11.11.1-1.1-1.1-0.90.91.20.91.21.2-1.01.0-1.2-1.21.21.2-1.21.21.1-1.21.21.01.2-1.2-1.2-1.21.21.11.11.01.31.1-1.11.01.1
Time to tail flick, test, after self-admin2.52.63.41.7-1.91.91.7-1.6-1.4-1.51.51.81.41.81.4-1.81.8-1.4-1.41.41.4-1.81.51.7-1.81.80.61.8-1.8-1.8-1.81.71.71.71.41.71.6-1.61.31.4
Delta time to tail flick, vehicle, before/after SA1.21.13.11.3-0.80.80.7-0.7-0.7-0.60.61.10.41.10.7-0.70.7-0.7-0.70.70.7-1.21.00.9-1.31.3-0.21.3-1.3-1.3-1.41.31.21.11.71.51.5-1.51.21.4
Delta time to tail flick, test, before/after SA0.10.10.5-0.70.3-0.3-0.30.30.50.3-0.3-0.3-0.2-0.3-0.50.3-0.30.50.5-0.5-0.50.3-0.4-0.10.3-0.3-0.5-0.30.30.30.3-0.3-0.2-0.2-0.3-0.3-0.10.1-0.1-0.2
Tibia length0.82.23.31.2-1.61.61.5-1.5-1.6-1.31.31.51.71.51.8-1.11.1-1.8-1.81.81.8-1.61.81.4-1.51.50.11.5-1.6-1.4-1.61.41.31.41.31.61.6-1.61.01.1
Ambulatory time before self-admin0.10.21.0-1.00.5-0.5-0.30.30.30.7-0.7-0.40.0-0.4-0.50.5-0.50.50.5-0.5-0.50.4-0.6-0.30.4-0.4-0.3-0.40.40.40.4-0.3-0.3-0.3-0.9-0.5-0.50.5-0.2-0.0
Ambulatory time after self-admin1.01.22.7-1.61.5-1.5-1.51.51.41.6-1.6-0.8-1.3-0.8-1.41.6-1.61.41.4-1.4-1.40.7-1.2-0.60.5-0.5-1.6-0.40.40.30.4-0.3-0.2-0.20.10.20.2-0.20.70.5
Bone: tissue strength0.50.51.6-0.3-0.00.00.4-0.4-0.9-0.20.20.40.70.40.9-0.20.2-1.0-1.01.01.0-0.40.90.8-0.50.50.40.6-0.5-0.7-0.40.70.80.90.30.80.7-0.71.31.1
Total heroin consumption0.30.40.6-0.50.6-0.6-0.70.70.60.6-0.6-0.7-0.7-0.7-0.40.6-0.60.40.4-0.4-0.40.7-0.5-0.70.6-0.6-0.1-0.70.70.60.7-0.6-0.7-0.7-0.7-0.8-0.70.7-0.5-0.6
Bone: trabecular number0.20.42.4-0.20.4-0.4-0.20.20.00.2-0.20.2-0.30.3-0.20.5-0.50.20.2-0.2-0.2-0.30.10.6-0.40.50.50.5-0.5-0.7-0.40.70.80.81.10.90.9-0.91.51.3
Bone: trabecular spacing1.21.62.61.5-1.61.61.5-1.5-1.5-1.31.31.41.51.31.6-1.41.4-1.6-1.61.61.6-1.31.51.1-1.21.20.81.1-1.1-1.1-1.21.11.01.00.90.90.9-0.90.40.5
Bone: trabecular thickness0.60.81.4-0.90.8-0.8-0.90.90.70.7-0.7-1.0-0.6-0.9-0.50.8-0.80.50.5-0.5-0.50.9-0.7-1.00.9-0.9-0.9-0.90.91.00.9-1.0-1.0-1.1-1.2-1.1-1.11.1-1.1-0.8
Bone: trabecular tissue density0.10.21.5-0.3-0.20.2-0.00.10.2-0.00.0-0.30.3-0.2-0.0-0.00.00.00.0-0.0-0.00.3-0.2-0.50.3-0.3-0.8-0.40.40.50.3-0.5-0.7-0.7-0.9-0.7-0.70.7-1.2-0.8
Water consumed over 24 hours1.21.62.90.8-1.01.01.0-1.0-0.9-1.01.01.31.01.40.8-0.60.6-0.8-0.80.80.8-1.41.01.4-1.51.5-0.11.5-1.5-1.6-1.51.61.51.51.41.61.6-1.61.61.7
Number of responses in last shaping day0.10.21.7-0.40.4-0.4-0.30.30.10.6-0.6-0.1-0.2-0.00.00.6-0.6-0.0-0.00.00.0-0.10.1-0.1-0.20.2-1.30.2-0.2-0.2-0.20.20.20.20.30.50.5-0.50.70.6